Hub : Genes

RAD51L1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Colon Adenocarcinoma 0.2240 0.0730 0.0016 0.061 0.049 0.055 NA 0.065 0.0002 0.00083 0.00039 NA 0.00012
2 TCGA Lung Adenocarcinoma 0.0427 0.0199 0.0060 -0.002 0.004 -0.002 NA -0.002 0.5700 0.09900 0.98000 NA 0.81000

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.4 0.6 0.9 -0.6 -0.9
Bipolar Disorder or Schizophrenia 0.0 0.1 0.2 0.0 -0.4
Depressed Affect (Nagel 2018) 0.5 1.0 1.9 -1.4 0.3
Depression (Nagel 2018) 0.0 0.0 0.0 -0.1 -0.2
Intelligence (Savage-Jansen 2018) 0.5 1.5 3.0 1.7 0.1
Neuroticism (Nagel 2018) 0.4 1.0 1.5 -1.2 0.7
Schizophrenia (2018) 0.1 0.2 0.3 0.5 0.3
Schizophrenia vs Biploar Disorder 2.1 2.8 5.4 2.3 0.4
Worry (Nagel 2018) 0.1 0.3 0.6 -0.8 0.0
Alzheimer’s Disease (in mother) 0.2 0.2 0.5 -0.7 -0.0
Alzheimer’s Disease (in father) 2.8 3.1 4.9 -1.1 2.2
Alzheimer’s Disease (including proxy) 1.1 1.6 2.2 -1.5 1.0
Crohns Disease (2017) 0.4 0.9 1.8 0.0 1.4
Irritable Bowel Disease (IBD) 0.1 0.3 0.4 -0.5 0.6
Ulcerative Colitis (UC) 0.3 0.6 1.3 -1.1 0.2
Major Depression (MDD) 0.9 1.1 1.6 1.3 0.8
Reaction Time 0.8 1.5 2.4 -0.8 1.5
Verbal and Numeric Reasoning (VNR) 1.0 2.4 3.3 1.8 -1.2
Breast Cancer 5.5 13.2 26.3 5.1 -0.1
Ovarian Cancer 0.1 0.1 0.2 0.1 -0.4
Prostate Cancer 3.4 4.8 9.2 0.6 -3.0
Age at First Birth 0.0 0.0 0.1 -0.2 0.0
Bipolar Disorder (2011) 2.3 2.2 4.3 -0.4 -2.1
Body Mass Index (BMI) (2010) 0.5 0.7 1.4 0.1 1.2
Coronary Artery Disease (CAD) 0.1 0.1 0.2 0.5 -0.1
Crohns Disease (2012) 0.0 0.0 0.0 -0.1 0.1
Mean Putamen Volume 1.0 1.1 2.1 1.4 0.4
Fasting Glucose 0.8 1.0 1.3 1.1 0.8
HbA1C 0.6 0.6 0.8 0.9 0.7
HDL Cholesterol 1.2 2.1 3.9 -2.0 0.5
LDL Cholesterol 2.6 4.1 7.5 0.9 2.7
Lupus 0.0 0.0 0.0 0.2 0.1
Neuroticism (2016) 0.5 0.7 0.9 1.0 0.7
Primary Biliary Cirrhosis 0.6 0.8 1.4 0.4 -1.2
Rheumatoid Arthritis 1.3 1.8 3.5 1.9 0.3
Schizophrenia (2014) 0.0 0.1 0.2 0.4 -0.2
Triglycerides 0.2 0.3 0.5 0.2 0.7
Type 2 Diabetes (T2D) (2012) 0.7 0.8 1.5 -1.2 -0.1
Ulcerative Colitis 0.3 0.5 0.7 -0.8 -0.6
Blood Eosinophil Count 0.4 3.0 3.1 1.8 -1.7
Blood Platelet Count 2.8 32.6 44.6 4.5 -6.7
Blood Red Count 1.9 18.5 34.8 1.5 5.9
Blood White Count 0.2 1.3 2.4 -0.5 1.6
Heel T-Score 0.4 3.0 3.1 1.8 -1.7
BMI 0.2 1.1 2.1 1.5 -0.4
Height 0.8 15.1 27.0 1.8 -5.2
Waist Hip Ratio (WHR) 1.2 5.3 8.8 1.3 -3.0
Systolic Blood Pressure 1.2 5.9 9.5 1.5 -3.1
Smoking Status 0.6 1.4 2.2 -0.8 1.5
Allergy or Eczema 0.2 0.6 0.8 -0.9 0.5
Cardiovascular Disease 1.0 3.4 5.2 2.3 -1.3
Hypothyroidism (self reported) 0.5 1.1 2.0 -0.4 -1.4
Respiratory disease 0.2 0.5 0.7 -0.6 0.8
Type 2 Diabetes (T2D) (2018) 0.3 0.6 0.8 0.6 -0.9
Lung FEV1/FVC ratio 0.7 3.3 6.6 0.1 -2.6
Lung FVC 0.7 3.7 7.3 2.7 -0.3
Neuroticism 0.9 2.1 4.2 -2.0 -0.0
Chronotype (morning person) 1.6 3.6 5.8 -1.2 2.4
Hair Pigment 0.3 8.1 14.3 -1.4 -3.8
Tanning 0.3 3.3 6.5 -2.5 -0.3
Hand grip strength (left) 2.1 5.6 10.2 1.0 -3.2
Number of treatments/medications taken 1.3 2.3 2.3 -1.5 -1.5
Average weekly spirits intake 1.1 1.3 2.3 0.6 1.5
Sensitivity / hurt feelings 0.6 1.1 1.7 -1.3 0.6
Frequency of depressed mood in last 2 weeks 0.7 1.0 1.6 -0.5 1.3
Hearing difficulty/problems: Yes 0.9 1.4 1.9 -0.9 1.4
Relative age of first facial hair 0.6 1.3 2.3 -1.5 0.4
Other serious medical condition/disability diagnosed by doctor 1.1 1.5 2.8 -0.4 -1.7
Ever used hormone-replacement therapy (HRT) 1.6 2.0 2.7 -1.6 1.2
Ever had hysterectomy (womb removed) 1.4 1.6 2.2 1.5 1.0
Systolic blood pressure, automated reading 1.4 4.0 7.9 -0.2 -2.8
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.4 0.6 -0.2
Angina 1.6 2.1 4.1 -0.0 2.0
Medication for hormone replacement therapy 0.9 1.0 1.4 -0.8 -1.2
Vitamin and mineral supplements 0.5 0.7 1.1 1.0 0.5
Supplements: Zinc 0.4 0.5 0.9 -0.2 0.9
Medication: Co-codamol 1.3 1.5 2.1 0.9 1.5
Medication: Metformin 0.1 0.1 0.2 0.3 0.4
Diabetes (father) 0.7 0.8 1.4 -0.6 -1.2
Diabetes (mother) 1.5 1.9 2.1 1.5 -1.3
Severe depression (siblings) 3.0 3.3 5.4 -2.3 -1.1
Pack years adult smoking proportion 0.5 0.8 1.5 0.1 1.2
Impedance of leg (right) 1.1 5.2 9.8 -0.8 3.1
Leg fat-free mass (left) 1.0 5.3 6.7 2.6 -2.0
Trunk fat percentage 0.1 0.6 1.2 1.1 -0.1
Hand grip strength (right) 1.4 3.8 6.9 0.8 -2.6
Townsend deprivation index at recruitment 0.6 0.9 1.8 -0.2 1.3
Current tobacco smoking 0.5 0.8 0.9 -0.8 0.9
Average weekly fortified wine intake 0.4 0.5 0.7 0.8 0.6
Maternal smoking around birth 0.2 0.4 0.7 -0.0 0.8
Fed-up feelings 1.0 1.8 3.7 -0.1 1.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.3 2.4 -0.3 1.6
Relative age voice broke 0.3 0.5 0.9 -0.2 -1.0
Taking other prescription medications 1.4 2.1 3.3 -1.8 -1.0
Age when periods started (menarche) 0.4 1.0 1.7 1.3 0.5
Bilateral oophorectomy (both ovaries removed) 1.4 1.6 2.1 1.4 1.1
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.9 1.2 0.8 -1.1
Tinnitus: Yes, but not now, but have in the past 0.4 0.5 0.6 0.8 0.6
Qualifications: CSEs or equivalent 0.2 0.3 0.6 0.1 -0.8
Serious illness, injury or assault to yourself 0.1 0.1 0.1 0.2 0.4
High blood pressure 2.1 5.8 9.8 1.3 -3.1
Hayfever, allergic rhinitis or eczema 0.2 0.4 0.5 -0.7 0.5
Multivitamins +/- minerals 0.7 0.9 1.3 -1.1 -0.7
Stomach or abdominal pain in last month 0.6 0.8 1.3 -0.5 1.1
Supplements: Glucosamine 0.6 0.8 1.0 0.8 -1.0
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 0.9 -1.0 0.0
Medication: Atenolol 2.3 2.9 5.7 0.2 -2.4
Medication: Levothyroxine sodium 0.5 0.8 1.6 -0.2 -1.2
Sitting height 1.2 8.8 10.2 2.7 -3.2
Chronic bronchitis/emphysema (father) 1.5 1.8 3.6 -0.0 -1.9
High blood pressure (mother) 2.2 3.1 6.1 -0.3 -2.5
Body mass index (BMI) 0.5 2.0 3.5 1.9 -0.7
Impedance of leg (left) 0.8 3.8 5.7 -1.4 2.4
Leg predicted mass (left) 1.0 5.5 7.1 2.7 -1.9
Trunk fat mass 0.4 1.6 2.4 1.5 -0.9
Waist circumference 0.9 3.2 5.7 2.4 -0.8
Number of incorrect matches in round 0.2 0.4 0.5 -0.7 -0.5
Past tobacco smoking 1.2 2.1 3.7 0.7 -1.9
Alcohol usually taken with meals 1.6 2.5 2.8 -1.7 -1.5
Nervous feelings 3.2 6.0 6.6 -2.6 2.3
Frequency of tenseness / restlessness in last 2 weeks 0.0 0.1 0.1 -0.4 -0.1
Hearing difficulty/problems with background noise 0.0 0.0 0.0 -0.2 0.2
Hair/balding pattern: Pattern 2 0.8 1.0 1.3 1.1 -0.8
Had menopause 0.2 0.3 0.5 -0.7 -0.2
Had other major operations 0.5 0.6 1.0 -1.0 -0.4
Forced vital capacity (FVC) 1.4 5.2 5.8 2.1 -2.4
Heel bone mineral density (BMD) T-score, automated (right) 0.8 1.9 2.6 1.6 -1.1
Ever unenthusiastic/disinterested for a whole week 1.6 1.9 3.3 1.8 0.7
Qualifications: None of the above 0.8 1.8 2.7 1.0 1.6
Financial difficulties in last 2 years 1.0 1.4 1.7 1.3 1.1
Mouth/teeth dental problems 1.3 2.0 2.5 1.6 1.2
Heart attack 1.1 1.4 1.5 -1.2 -1.1
Allergy 0.1 0.2 0.4 0.3 0.6
Pain all over the body in last month 0.1 0.2 0.3 -0.5 0.1
Diabetes (self-reported) 0.2 0.4 0.7 -0.8 -0.2
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 0.4 -0.6 0.6
Medication: Ramipril 0.8 1.1 2.1 -0.2 -1.4
Medication: Simvastatin 0.1 0.2 0.4 -0.6 0.1
Fluid intelligence score 1.4 2.8 4.2 1.2 -2.0
Illnesses of siblings 0.1 0.1 0.1 0.3 0.2
Neuroticism score 0.5 1.1 2.2 -1.5 -0.0
Weight 1.0 4.9 6.6 2.6 -1.8
Impedance of arm (right) 0.5 2.1 2.4 -1.4 1.5
Arm fat percentage (right) 0.1 0.6 1.1 1.1 -0.2
Trunk fat-free mass 0.8 4.6 6.1 1.8 -2.5
Hip circumference 0.4 1.8 3.3 1.8 0.5
Time employed in main current job 1.4 1.7 2.4 -0.9 -1.6
Alcohol intake versus 10 years previously 1.9 2.9 3.7 1.4 1.9
Father’s age at death 0.4 0.5 0.8 -0.9 0.5
Worrier / anxious feelings 0.1 0.2 0.3 0.1 0.6
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.3 2.1 -1.4 -0.7
Falls in the last year 0.7 1.0 1.9 -1.4 -0.0
Hair/balding pattern: Pattern 3 0.7 1.1 2.1 0.2 1.4
Number of live births 0.8 1.1 1.8 -1.4 0.6
Forced expiratory volume in 1-second (FEV1) 2.2 7.5 10.9 2.0 -3.3
Pulse rate 0.1 0.1 0.2 -0.5 0.3
Happiness 0.0 0.0 0.0 0.1 0.2
Noisy workplace 3.8 4.7 8.4 1.0 2.9
Qualifications: A levels/AS levels or equivalent 1.2 2.7 4.3 1.0 -2.1
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.5 0.6 0.7 -0.7
Mouth/teeth dental problems: Dentures 1.3 2.2 4.1 -0.6 -2.0
Asthma 1.4 2.8 5.3 0.5 2.3
Medication: Ibuprofen (e.g. Nurofen) 2.0 2.6 3.8 -1.2 1.9
Medication: Cholesterol lowering 0.2 0.4 0.5 -0.5 -0.7
Depression (self-reported) 0.5 0.6 1.3 -1.1 0.1
Medication: Lansoprazole 0.1 0.2 0.2 0.5 0.3
Prospective memory result 0.5 0.6 0.7 0.8 0.8
Lung cancer (father) 0.7 0.9 1.2 -0.8 -1.1
Illnesses of mother 0.4 0.5 0.7 -0.8 0.6
Forced expiratory volume in 1-second (FEV1), Best measure 2.2 7.0 9.1 3.0 -2.2
Pulse wave Arterial Stiffness index 0.5 0.5 0.9 0.4 1.0
Impedance of arm (left) 0.2 0.9 1.2 -0.8 1.1
Arm fat mass (right) 0.5 2.2 3.1 1.8 -1.1
Trunk predicted mass 0.7 4.2 5.5 1.7 -2.3
Standing height 0.6 5.8 9.4 1.5 -3.1
Length of working week for main job 2.3 2.6 4.5 0.8 -2.1
Exposure to tobacco smoke at home 0.3 0.3 0.5 -0.2 0.7
Breastfed as a baby 4.6 5.7 9.5 3.1 1.4
Tense / ‘highly strung’ 0.8 1.3 2.6 -1.6 -0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 1.8 2.7 4.0 -1.2 2.0
Hair/balding pattern: Pattern 4 0.9 2.2 4.3 -2.1 0.1
Birth weight of first child 0.3 0.5 0.6 0.8 -0.5
Peak expiratory flow (PEF) 0.6 1.3 1.7 1.0 -1.3
Pulse wave reflection index 0.1 0.1 0.1 -0.4 0.0
Ever highly irritable/argumentative for 2 days 0.4 0.5 0.6 0.6 0.8
Loud music exposure frequency 1.3 1.4 2.8 1.7 0.2
Qualifications: O levels/GCSEs or equivalent 1.5 2.5 4.9 2.2 -0.0
Mouth/teeth dental problems: Bleeding gums 1.0 1.2 2.1 -0.6 1.5
Blood clot in the leg (DVT) 2.8 3.6 7.1 -0.5 -2.7
Medication: Paracetamol 0.8 1.3 1.7 -1.3 -0.9
Headache pain in last month 1.5 2.5 4.5 -2.1 -0.8
Medication for cholesterol, blood pressure or diabetes 0.3 0.4 0.5 0.7 0.6
Glaucoma (self-reported) 0.2 0.2 0.3 0.5 -0.4
Gout (self-reported) 0.3 0.4 0.8 -0.9 -0.1
Hypothyroidism/myxoedema (self-reported) 0.9 1.8 3.1 -0.6 -1.8
Medication: Amlodipine 0.8 1.1 1.4 1.2 -0.8
Medication: Ventolin 100micrograms inhaler 2.4 3.1 6.3 -2.5 0.2
Birth weight 0.5 1.0 1.9 0.3 1.4
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.2 0.5 -0.2
High blood pressure (siblings) 0.1 0.2 0.4 0.1 -0.6
Forced vital capacity (FVC), Best measure 1.9 7.0 10.9 3.3 -1.8
Body fat percentage 0.2 0.8 1.6 1.3 0.2
Leg fat percentage (right) 0.5 2.0 2.8 1.7 1.1
Arm fat-free mass (right) 1.1 5.7 7.1 2.7 -2.1
Exposure to tobacco smoke outside home 1.1 1.5 2.7 1.7 0.5
Comparative body size at age 10 0.1 0.2 0.4 0.1 -0.7
Number of full brothers 0.2 0.2 0.4 -0.2 0.6
Worry too long after embarrassment 0.7 1.1 2.2 -1.5 0.2
Seen a psychiatrist for nerves, anxiety, tension or depression 1.9 2.5 4.2 -0.8 2.1
Wheeze or whistling in the chest in last year 0.4 0.7 0.9 -0.7 -0.9
Number of children fathered 0.1 0.1 0.2 -0.3 0.4
Reason for reducing amount of alcohol drunk: Health precaution 1.6 1.9 3.5 -0.6 1.9
Age at first live birth 0.0 0.1 0.1 0.3 0.2
Pulse wave peak to peak time 0.7 0.9 1.7 -0.1 -1.3
Health satisfaction 0.0 0.1 0.1 -0.3 0.1
Shortness of breath walking on level ground 0.2 0.3 0.4 -0.3 0.7
Qualifications: College or University degree 0.3 0.9 1.6 -0.5 -1.3
Eye problems/disorders: None of the above 2.2 2.5 4.1 2.0 -1.0
Mouth/teeth dental problems: Loose teeth 0.4 0.5 1.0 -1.0 0.1
Emphysema/chronic bronchitis 0.3 0.4 0.5 -0.5 -0.7
Medication for pain relief, constipation, heartburn 0.5 0.8 1.6 1.2 0.2
Neck or shoulder pain in last month 0.1 0.1 0.1 -0.3 0.3
Medication: Blood pressure 0.7 1.3 2.5 0.0 -1.6
Angina (self-reported) 1.7 2.2 4.3 -0.2 2.1
Migraine (self-reported) 0.1 0.2 0.2 0.4 -0.5
Medication: Ibuprofen 2.3 2.8 4.4 -1.1 2.1
Medication: Allopurinol 0.7 0.9 1.7 -1.3 -0.5
Medication: Omeprazole 1.9 2.2 4.0 -2.0 -0.7
Medication: Seretide 50 evohaler 0.8 0.9 1.4 -0.6 1.2
Mean time to correctly identify matches 1.4 2.6 2.9 -1.7 1.5
Heart disease (mother) 1.8 2.2 4.3 0.4 2.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.2 0.3 -0.6 -0.4
Whole body fat mass 0.5 1.9 3.1 1.8 -0.8
Leg fat mass (right) 0.6 2.3 4.4 2.1 -0.4
Arm predicted mass (right) 1.0 5.0 5.5 2.3 -2.1
Pulse rate, automated reading 0.3 0.9 1.4 -1.2 0.7
Alcohol intake frequency. 0.6 1.5 2.9 -0.3 1.7
Comparative height size at age 10 0.6 3.3 6.2 -0.6 -2.5
Number of full sisters 1.5 1.8 3.6 -0.1 1.9
Suffer from ‘nerves’ 0.6 1.0 1.3 -0.8 1.2
Overall health rating 0.2 0.3 0.6 -0.3 0.8
Chest pain or discomfort 0.2 0.3 0.6 -0.8 0.2
Had major operations 2.5 3.0 5.7 2.4 0.5
Age at last live birth 0.2 0.3 0.5 -0.7 -0.3
Family relationship satisfaction 1.3 1.6 3.3 1.8 -0.1
Leg pain on walking 0.9 1.2 2.3 -1.5 -0.3
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 0.4 0.6 -0.1
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.3 0.5 0.3
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 0.9 -0.4 -0.9
Medication: Aspirin 0.5 0.6 1.2 -0.0 -1.1
Supplements: Vitamin C 0.1 0.1 0.2 0.4 0.3
Knee pain experienced in last month 0.6 1.0 1.9 1.4 0.2
Hypertension (Self-reported) 1.7 4.7 7.7 1.3 -2.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.5 1.8 1.8 -1.4 -1.3
Illnesses of father: Heart disease 0.1 0.2 0.3 0.5 0.2
Illnesses of siblings: Diabetes 2.3 2.9 5.7 -0.0 -2.4
Smoking status: Previous 0.8 1.2 2.2 -0.4 1.5
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.2 2.4 1.6 -0.2
Whole body fat-free mass 0.9 5.3 5.8 2.2 -2.4
Leg fat-free mass (right) 1.2 6.5 6.7 2.5 -2.6
Arm fat percentage (left) 0.3 1.0 1.9 1.4 -0.4
Average weekly red wine intake 0.3 0.4 0.7 -0.3 -0.8
Handedness (chirality/laterality): Left-handed 0.8 0.9 1.6 -1.3 0.5
Mood swings 0.4 0.8 1.6 -1.3 0.2
Loneliness, isolation 0.1 0.2 0.3 -0.6 0.3
Long-standing illness, disability or infirmity 0.5 0.7 1.1 -1.0 -0.6
Ever had bowel cancer screening 4.0 4.7 7.3 -2.7 1.4
Diabetes diagnosed by doctor 0.1 0.2 0.3 0.3 0.5
Ever had stillbirth, spontaneous miscarriage or termination 5.1 5.4 10.1 -3.2 0.8
Friendships satisfaction 0.6 0.7 1.5 1.2 0.0
Qualifications: nursing, teaching 0.1 0.1 0.1 0.4 -0.4
Commuting to job workplace: Walk 0.1 0.1 0.1 0.3 0.3
Eye problems/disorders: Cataract 2.7 3.2 4.3 -2.1 1.4
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 0.7 -0.9 0.4
Medication for cholesterol 1.3 1.9 3.7 -1.9 0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.3 0.6 -0.1 -0.8
Back pain experienced in last month 0.4 0.6 1.2 -0.3 1.1
Mineral and other dietary supplements 0.2 0.3 0.6 0.8 -0.1
Breast cancer (self-reported) 1.3 1.6 2.2 -1.5 1.0
Asthma (self-reported) 1.0 1.9 3.8 0.0 1.9
Osteoporosis (self-reported) 0.3 0.3 0.6 0.8 0.2
Osteoarthritis (self-reported) 0.6 0.7 1.5 1.2 0.0
Medication: Aspirin 0.3 0.4 0.7 -0.0 -0.8
Medication: Gliclazide 0.3 0.3 0.5 0.4 0.7
Illnesses of father: None of the above (group 1) 1.1 1.4 1.8 -1.0 1.3
Smoking status: Current 0.7 1.1 1.4 -0.9 1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.3 2.7 5.3 0.4 -2.3
Whole body water mass 1.0 5.6 6.1 2.3 -2.5
Leg predicted mass (right) 1.2 6.5 7.2 2.4 -2.7
Arm fat mass (left) 0.6 2.6 3.9 2.0 -1.1
Number of self-reported non-cancer illnesses 0.1 0.1 0.2 0.4 -0.3
Average weekly champagne plus white wine intake 1.1 1.5 2.2 -0.9 -1.5
Miserableness 0.7 1.3 2.5 -0.3 1.6
Guilty feelings 0.0 0.1 0.1 -0.2 0.3
Wears glasses or contact lenses 2.5 2.9 4.8 -2.2 -1.0
Ever taken oral contraceptive pill 0.6 0.7 1.3 -0.1 -1.1
Hearing aid user 0.8 0.9 1.1 0.8 1.1
Mother’s age at death 1.1 1.4 1.6 1.1 -1.3
Financial situation satisfaction 3.6 4.5 4.9 2.0 2.2
Tinnitus: Yes, now most or all of the time 0.3 0.4 0.6 0.4 -0.8
Commuting to job workplace: Public transport 0.6 0.8 1.2 0.6 -1.1
Eye problems/disorders: Glaucoma 0.5 0.6 1.2 1.1 0.0
Medication: Blood pressure 1.8 3.5 4.3 2.1 -1.7
Pain type(s) experienced in last month: Hip pain 0.2 0.3 0.5 -0.1 0.7
Supplements: Fish oil (including cod liver oil) 0.9 1.2 2.1 -1.4 0.6
High cholesterol (Self-reported) 0.1 0.2 0.2 -0.3 -0.4
Medication: Bendroflumethiazide 0.5 0.8 1.6 0.3 -1.3
Medication: Paracetamol 1.9 2.9 4.2 -2.0 -1.3
Medication: Lisinopril 0.1 0.1 0.3 0.5 -0.0
Medication: Atorvastatin 0.7 0.8 1.4 1.2 -0.5
Illnesses of father: High blood pressure 3.7 4.5 8.9 0.4 -3.0
Alcohol drinker status: Never 0.1 0.1 0.2 -0.5 0.2
Ever smoked 0.6 1.0 1.7 -0.5 1.3
Basal metabolic rate 1.0 5.4 5.9 2.4 -2.2
Leg fat percentage (left) 0.3 1.1 1.7 1.3 0.6
Arm fat-free mass (left) 0.7 3.6 4.5 2.1 -1.7
Number of operations (self-reported) 0.5 0.7 0.8 0.8 0.9
Average weekly beer plus cider intake 0.3 0.4 0.8 0.9 0.3
Irritability 1.5 2.6 4.0 -2.0 -1.1
Risk taking 0.2 0.3 0.4 0.6 0.3
Ever had prostate specific antigen (PSA) test 0.5 0.6 1.2 0.2 1.1
Fractured/broken bones in last 5 years 1.8 2.4 4.7 2.2 -0.1
Age started oral contraceptive pill 0.0 0.0 0.0 -0.0 0.0
Diastolic blood pressure, automated reading 0.4 1.3 2.2 0.5 -1.5
Ever depressed for a whole week 0.8 1.0 2.0 1.4 0.3
Unable to work because of sickness or disability 1.3 1.7 3.5 -0.1 1.9
Commuting to job workplace: Cycle 1.0 1.2 2.5 1.6 -0.0
Myopia 2.2 3.2 4.1 1.5 -2.0
Vascular/heart problems diagnosed by doctor 1.6 4.5 7.3 -1.3 2.7
Cholesterol lowering medication 0.6 1.0 1.8 1.3 0.3
Medication: Omeprazole (e.g. Zanprol) 2.1 2.6 2.8 -1.7 -1.5
Pain experienced in last month 0.3 0.5 0.9 0.0 -1.0
Supplements: Calcium 0.2 0.3 0.5 0.7 0.3
Basal cell carcinoma (self-reported) 1.2 1.5 2.7 0.5 1.6
Heart attack/myocardial infarction (self-reported) 1.2 1.5 1.6 -1.2 -1.3
Deep venous thrombosis (DVT) (self-reported) 2.9 3.7 7.0 -0.6 -2.6
Heart disease (siblings) 1.6 2.0 2.9 -1.0 1.7
Alcohol drinker status: Previous 3.7 4.2 8.4 -0.2 2.9
Pack years of smoking 0.6 0.9 1.8 -0.0 1.3
Impedance of whole body 0.5 2.6 3.9 -1.2 2.0
Leg fat mass (left) 0.5 1.9 3.5 1.9 -0.6
Arm predicted mass (left) 0.9 4.6 5.9 2.4 -1.8