TWAS hub - RAD51L1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Colon Adenocarcinoma	0.2240	0.0730	0.0016	0.061	0.049	0.055	NA	0.065	0.0002	0.00083	0.00039	NA	0.00012
2	TCGA	Lung Adenocarcinoma	0.0427	0.0199	0.0060	-0.002	0.004	-0.002	NA	-0.002	0.5700	0.09900	0.98000	NA	0.81000

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Breast Cancer	5.5	13.2	26.3	5.1	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	5.1	5.4	10.1	-3.2	0.8
Breastfed as a baby	4.6	5.7	9.5	3.1	1.4
Ever had bowel cancer screening	4.0	4.7	7.3	-2.7	1.4
Noisy workplace	3.8	4.7	8.4	1.0	2.9
Illnesses of father: High blood pressure	3.7	4.5	8.9	0.4	-3.0
Alcohol drinker status: Previous	3.7	4.2	8.4	-0.2	2.9
Financial situation satisfaction	3.6	4.5	4.9	2.0	2.2
Prostate Cancer	3.4	4.8	9.2	0.6	-3.0
Nervous feelings	3.2	6.0	6.6	-2.6	2.3
Severe depression (siblings)	3.0	3.3	5.4	-2.3	-1.1
Deep venous thrombosis (DVT) (self-reported)	2.9	3.7	7.0	-0.6	-2.6
Alzheimer’s Disease (in father)	2.8	3.1	4.9	-1.1	2.2
Blood Platelet Count	2.8	32.6	44.6	4.5	-6.7
Blood clot in the leg (DVT)	2.8	3.6	7.1	-0.5	-2.7
Eye problems/disorders: Cataract	2.7	3.2	4.3	-2.1	1.4
LDL Cholesterol	2.6	4.1	7.5	0.9	2.7
Had major operations	2.5	3.0	5.7	2.4	0.5
Wears glasses or contact lenses	2.5	2.9	4.8	-2.2	-1.0
Medication: Ventolin 100micrograms inhaler	2.4	3.1	6.3	-2.5	0.2
Bipolar Disorder (2011)	2.3	2.2	4.3	-0.4	-2.1
Medication: Atenolol	2.3	2.9	5.7	0.2	-2.4
Length of working week for main job	2.3	2.6	4.5	0.8	-2.1
Medication: Ibuprofen	2.3	2.8	4.4	-1.1	2.1
Illnesses of siblings: Diabetes	2.3	2.9	5.7	-0.0	-2.4
High blood pressure (mother)	2.2	3.1	6.1	-0.3	-2.5
Forced expiratory volume in 1-second (FEV1)	2.2	7.5	10.9	2.0	-3.3
Forced expiratory volume in 1-second (FEV1), Best measure	2.2	7.0	9.1	3.0	-2.2
Eye problems/disorders: None of the above	2.2	2.5	4.1	2.0	-1.0
Myopia	2.2	3.2	4.1	1.5	-2.0
Schizophrenia vs Biploar Disorder	2.1	2.8	5.4	2.3	0.4
Hand grip strength (left)	2.1	5.6	10.2	1.0	-3.2
High blood pressure	2.1	5.8	9.8	1.3	-3.1
Medication: Omeprazole (e.g. Zanprol)	2.1	2.6	2.8	-1.7	-1.5
Medication: Ibuprofen (e.g. Nurofen)	2.0	2.6	3.8	-1.2	1.9
Blood Red Count	1.9	18.5	34.8	1.5	5.9
Alcohol intake versus 10 years previously	1.9	2.9	3.7	1.4	1.9
Forced vital capacity (FVC), Best measure	1.9	7.0	10.9	3.3	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	4.2	-0.8	2.1
Medication: Omeprazole	1.9	2.2	4.0	-2.0	-0.7
Medication: Paracetamol	1.9	2.9	4.2	-2.0	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.7	4.0	-1.2	2.0
Heart disease (mother)	1.8	2.2	4.3	0.4	2.1
Medication: Blood pressure	1.8	3.5	4.3	2.1	-1.7
Fractured/broken bones in last 5 years	1.8	2.4	4.7	2.2	-0.1
Angina (self-reported)	1.7	2.2	4.3	-0.2	2.1
Hypertension (Self-reported)	1.7	4.7	7.7	1.3	-2.8
Chronotype (morning person)	1.6	3.6	5.8	-1.2	2.4
Ever used hormone-replacement therapy (HRT)	1.6	2.0	2.7	-1.6	1.2
Angina	1.6	2.1	4.1	-0.0	2.0
Alcohol usually taken with meals	1.6	2.5	2.8	-1.7	-1.5
Ever unenthusiastic/disinterested for a whole week	1.6	1.9	3.3	1.8	0.7
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.9	3.5	-0.6	1.9
Vascular/heart problems diagnosed by doctor	1.6	4.5	7.3	-1.3	2.7
Heart disease (siblings)	1.6	2.0	2.9	-1.0	1.7
Diabetes (mother)	1.5	1.9	2.1	1.5	-1.3
Chronic bronchitis/emphysema (father)	1.5	1.8	3.6	-0.0	-1.9
Qualifications: O levels/GCSEs or equivalent	1.5	2.5	4.9	2.2	-0.0
Headache pain in last month	1.5	2.5	4.5	-2.1	-0.8
Number of full sisters	1.5	1.8	3.6	-0.1	1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	1.8	-1.4	-1.3
Irritability	1.5	2.6	4.0	-2.0	-1.1
Ever had hysterectomy (womb removed)	1.4	1.6	2.2	1.5	1.0
Systolic blood pressure, automated reading	1.4	4.0	7.9	-0.2	-2.8
Hand grip strength (right)	1.4	3.8	6.9	0.8	-2.6
Taking other prescription medications	1.4	2.1	3.3	-1.8	-1.0
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	2.1	1.4	1.1
Forced vital capacity (FVC)	1.4	5.2	5.8	2.1	-2.4
Fluid intelligence score	1.4	2.8	4.2	1.2	-2.0
Time employed in main current job	1.4	1.7	2.4	-0.9	-1.6
Asthma	1.4	2.8	5.3	0.5	2.3
Mean time to correctly identify matches	1.4	2.6	2.9	-1.7	1.5
Rheumatoid Arthritis	1.3	1.8	3.5	1.9	0.3
Number of treatments/medications taken	1.3	2.3	2.3	-1.5	-1.5
Medication: Co-codamol	1.3	1.5	2.1	0.9	1.5
Mouth/teeth dental problems	1.3	2.0	2.5	1.6	1.2
Mouth/teeth dental problems: Dentures	1.3	2.2	4.1	-0.6	-2.0
Loud music exposure frequency	1.3	1.4	2.8	1.7	0.2
Family relationship satisfaction	1.3	1.6	3.3	1.8	-0.1
Medication for cholesterol	1.3	1.9	3.7	-1.9	0.4
Breast cancer (self-reported)	1.3	1.6	2.2	-1.5	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	5.3	0.4	-2.3
Unable to work because of sickness or disability	1.3	1.7	3.5	-0.1	1.9
HDL Cholesterol	1.2	2.1	3.9	-2.0	0.5
Waist Hip Ratio (WHR)	1.2	5.3	8.8	1.3	-3.0
Systolic Blood Pressure	1.2	5.9	9.5	1.5	-3.1
Sitting height	1.2	8.8	10.2	2.7	-3.2
Past tobacco smoking	1.2	2.1	3.7	0.7	-1.9
Qualifications: A levels/AS levels or equivalent	1.2	2.7	4.3	1.0	-2.1
Leg fat-free mass (right)	1.2	6.5	6.7	2.5	-2.6
Leg predicted mass (right)	1.2	6.5	7.2	2.4	-2.7
Basal cell carcinoma (self-reported)	1.2	1.5	2.7	0.5	1.6
Heart attack/myocardial infarction (self-reported)	1.2	1.5	1.6	-1.2	-1.3
Alzheimer’s Disease (including proxy)	1.1	1.6	2.2	-1.5	1.0
Average weekly spirits intake	1.1	1.3	2.3	0.6	1.5
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	2.8	-0.4	-1.7
Impedance of leg (right)	1.1	5.2	9.8	-0.8	3.1
Heart attack	1.1	1.4	1.5	-1.2	-1.1
Arm fat-free mass (right)	1.1	5.7	7.1	2.7	-2.1
Exposure to tobacco smoke outside home	1.1	1.5	2.7	1.7	0.5
Illnesses of father: None of the above (group 1)	1.1	1.4	1.8	-1.0	1.3
Average weekly champagne plus white wine intake	1.1	1.5	2.2	-0.9	-1.5
Mother’s age at death	1.1	1.4	1.6	1.1	-1.3
Verbal and Numeric Reasoning (VNR)	1.0	2.4	3.3	1.8	-1.2
Mean Putamen Volume	1.0	1.1	2.1	1.4	0.4
Cardiovascular Disease	1.0	3.4	5.2	2.3	-1.3
Leg fat-free mass (left)	1.0	5.3	6.7	2.6	-2.0
Fed-up feelings	1.0	1.8	3.7	-0.1	1.9
Leg predicted mass (left)	1.0	5.5	7.1	2.7	-1.9
Financial difficulties in last 2 years	1.0	1.4	1.7	1.3	1.1
Weight	1.0	4.9	6.6	2.6	-1.8
Mouth/teeth dental problems: Bleeding gums	1.0	1.2	2.1	-0.6	1.5
Arm predicted mass (right)	1.0	5.0	5.5	2.3	-2.1
Asthma (self-reported)	1.0	1.9	3.8	0.0	1.9
Whole body water mass	1.0	5.6	6.1	2.3	-2.5
Basal metabolic rate	1.0	5.4	5.9	2.4	-2.2
Commuting to job workplace: Cycle	1.0	1.2	2.5	1.6	-0.0
Major Depression (MDD)	0.9	1.1	1.6	1.3	0.8
Neuroticism	0.9	2.1	4.2	-2.0	-0.0
Hearing difficulty/problems: Yes	0.9	1.4	1.9	-0.9	1.4
Medication for hormone replacement therapy	0.9	1.0	1.4	-0.8	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.3	2.4	-0.3	1.6
Waist circumference	0.9	3.2	5.7	2.4	-0.8
Hair/balding pattern: Pattern 4	0.9	2.2	4.3	-2.1	0.1
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	3.1	-0.6	-1.8
Leg pain on walking	0.9	1.2	2.3	-1.5	-0.3
Whole body fat-free mass	0.9	5.3	5.8	2.2	-2.4
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.1	-1.4	0.6
Arm predicted mass (left)	0.9	4.6	5.9	2.4	-1.8
Reaction Time	0.8	1.5	2.4	-0.8	1.5
Fasting Glucose	0.8	1.0	1.3	1.1	0.8
Height	0.8	15.1	27.0	1.8	-5.2
Impedance of leg (left)	0.8	3.8	5.7	-1.4	2.4
Hair/balding pattern: Pattern 2	0.8	1.0	1.3	1.1	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	2.6	1.6	-1.1
Qualifications: None of the above	0.8	1.8	2.7	1.0	1.6
Medication: Ramipril	0.8	1.1	2.1	-0.2	-1.4
Trunk fat-free mass	0.8	4.6	6.1	1.8	-2.5
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	2.1	-1.4	-0.7
Number of live births	0.8	1.1	1.8	-1.4	0.6
Tense / ‘highly strung’	0.8	1.3	2.6	-1.6	-0.3
Medication: Paracetamol	0.8	1.3	1.7	-1.3	-0.9
Medication: Amlodipine	0.8	1.1	1.4	1.2	-0.8
Medication: Seretide 50 evohaler	0.8	0.9	1.4	-0.6	1.2
Smoking status: Previous	0.8	1.2	2.2	-0.4	1.5
Handedness (chirality/laterality): Left-handed	0.8	0.9	1.6	-1.3	0.5
Hearing aid user	0.8	0.9	1.1	0.8	1.1
Ever depressed for a whole week	0.8	1.0	2.0	1.4	0.3
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.5	-1.2	-0.1
Lung FEV1/FVC ratio	0.7	3.3	6.6	0.1	-2.6
Lung FVC	0.7	3.7	7.3	2.7	-0.3
Frequency of depressed mood in last 2 weeks	0.7	1.0	1.6	-0.5	1.3
Diabetes (father)	0.7	0.8	1.4	-0.6	-1.2
Multivitamins +/- minerals	0.7	0.9	1.3	-1.1	-0.7
Falls in the last year	0.7	1.0	1.9	-1.4	-0.0
Hair/balding pattern: Pattern 3	0.7	1.1	2.1	0.2	1.4
Lung cancer (father)	0.7	0.9	1.2	-0.8	-1.1
Trunk predicted mass	0.7	4.2	5.5	1.7	-2.3
Worry too long after embarrassment	0.7	1.1	2.2	-1.5	0.2
Pulse wave peak to peak time	0.7	0.9	1.7	-0.1	-1.3
Medication: Blood pressure	0.7	1.3	2.5	0.0	-1.6
Medication: Allopurinol	0.7	0.9	1.7	-1.3	-0.5
Smoking status: Current	0.7	1.1	1.4	-0.9	1.2
Miserableness	0.7	1.3	2.5	-0.3	1.6
Medication: Atorvastatin	0.7	0.8	1.4	1.2	-0.5
Arm fat-free mass (left)	0.7	3.6	4.5	2.1	-1.7
HbA1C	0.6	0.6	0.8	0.9	0.7
Primary Biliary Cirrhosis	0.6	0.8	1.4	0.4	-1.2
Smoking Status	0.6	1.4	2.2	-0.8	1.5
Sensitivity / hurt feelings	0.6	1.1	1.7	-1.3	0.6
Relative age of first facial hair	0.6	1.3	2.3	-1.5	0.4
Townsend deprivation index at recruitment	0.6	0.9	1.8	-0.2	1.3
Stomach or abdominal pain in last month	0.6	0.8	1.3	-0.5	1.1
Supplements: Glucosamine	0.6	0.8	1.0	0.8	-1.0
Standing height	0.6	5.8	9.4	1.5	-3.1
Peak expiratory flow (PEF)	0.6	1.3	1.7	1.0	-1.3
Leg fat mass (right)	0.6	2.3	4.4	2.1	-0.4
Alcohol intake frequency.	0.6	1.5	2.9	-0.3	1.7
Comparative height size at age 10	0.6	3.3	6.2	-0.6	-2.5
Suffer from ‘nerves’	0.6	1.0	1.3	-0.8	1.2
Knee pain experienced in last month	0.6	1.0	1.9	1.4	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	2.4	1.6	-0.2
Friendships satisfaction	0.6	0.7	1.5	1.2	0.0
Osteoarthritis (self-reported)	0.6	0.7	1.5	1.2	0.0
Arm fat mass (left)	0.6	2.6	3.9	2.0	-1.1
Ever taken oral contraceptive pill	0.6	0.7	1.3	-0.1	-1.1
Commuting to job workplace: Public transport	0.6	0.8	1.2	0.6	-1.1
Ever smoked	0.6	1.0	1.7	-0.5	1.3
Cholesterol lowering medication	0.6	1.0	1.8	1.3	0.3
Pack years of smoking	0.6	0.9	1.8	-0.0	1.3
Depressed Affect (Nagel 2018)	0.5	1.0	1.9	-1.4	0.3
Intelligence (Savage-Jansen 2018)	0.5	1.5	3.0	1.7	0.1
Body Mass Index (BMI) (2010)	0.5	0.7	1.4	0.1	1.2
Neuroticism (2016)	0.5	0.7	0.9	1.0	0.7
Hypothyroidism (self reported)	0.5	1.1	2.0	-0.4	-1.4
Vitamin and mineral supplements	0.5	0.7	1.1	1.0	0.5
Pack years adult smoking proportion	0.5	0.8	1.5	0.1	1.2
Current tobacco smoking	0.5	0.8	0.9	-0.8	0.9
Medication: Levothyroxine sodium	0.5	0.8	1.6	-0.2	-1.2
Body mass index (BMI)	0.5	2.0	3.5	1.9	-0.7
Had other major operations	0.5	0.6	1.0	-1.0	-0.4
Neuroticism score	0.5	1.1	2.2	-1.5	-0.0
Impedance of arm (right)	0.5	2.1	2.4	-1.4	1.5
Depression (self-reported)	0.5	0.6	1.3	-1.1	0.1
Prospective memory result	0.5	0.6	0.7	0.8	0.8
Pulse wave Arterial Stiffness index	0.5	0.5	0.9	0.4	1.0
Arm fat mass (right)	0.5	2.2	3.1	1.8	-1.1
Birth weight	0.5	1.0	1.9	0.3	1.4
Leg fat percentage (right)	0.5	2.0	2.8	1.7	1.1
Medication for pain relief, constipation, heartburn	0.5	0.8	1.6	1.2	0.2
Whole body fat mass	0.5	1.9	3.1	1.8	-0.8
Medication: Aspirin	0.5	0.6	1.2	-0.0	-1.1
Long-standing illness, disability or infirmity	0.5	0.7	1.1	-1.0	-0.6
Eye problems/disorders: Glaucoma	0.5	0.6	1.2	1.1	0.0
Medication: Bendroflumethiazide	0.5	0.8	1.6	0.3	-1.3
Number of operations (self-reported)	0.5	0.7	0.8	0.8	0.9
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.2	0.2	1.1
Impedance of whole body	0.5	2.6	3.9	-1.2	2.0
Leg fat mass (left)	0.5	1.9	3.5	1.9	-0.6
Bipolar Disorder (2018)	0.4	0.6	0.9	-0.6	-0.9
Neuroticism (Nagel 2018)	0.4	1.0	1.5	-1.2	0.7
Crohns Disease (2017)	0.4	0.9	1.8	0.0	1.4
Blood Eosinophil Count	0.4	3.0	3.1	1.8	-1.7
Heel T-Score	0.4	3.0	3.1	1.8	-1.7
Supplements: Zinc	0.4	0.5	0.9	-0.2	0.9
Average weekly fortified wine intake	0.4	0.5	0.7	0.8	0.6
Age when periods started (menarche)	0.4	1.0	1.7	1.3	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	1.2	0.8	-1.1
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	0.6	0.8	0.6
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	0.9	-1.0	0.0
Trunk fat mass	0.4	1.6	2.4	1.5	-0.9
Hip circumference	0.4	1.8	3.3	1.8	0.5
Father’s age at death	0.4	0.5	0.8	-0.9	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	0.6	0.7	-0.7
Illnesses of mother	0.4	0.5	0.7	-0.8	0.6
Ever highly irritable/argumentative for 2 days	0.4	0.5	0.6	0.6	0.8
Wheeze or whistling in the chest in last year	0.4	0.7	0.9	-0.7	-0.9
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.0	-1.0	0.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	0.9	-0.4	-0.9
Mood swings	0.4	0.8	1.6	-1.3	0.2
Back pain experienced in last month	0.4	0.6	1.2	-0.3	1.1
Diastolic blood pressure, automated reading	0.4	1.3	2.2	0.5	-1.5
Ulcerative Colitis (UC)	0.3	0.6	1.3	-1.1	0.2
Ulcerative Colitis	0.3	0.5	0.7	-0.8	-0.6
Type 2 Diabetes (T2D) (2018)	0.3	0.6	0.8	0.6	-0.9
Hair Pigment	0.3	8.1	14.3	-1.4	-3.8
Tanning	0.3	3.3	6.5	-2.5	-0.3
Relative age voice broke	0.3	0.5	0.9	-0.2	-1.0
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.4	-0.6	0.6
Exposure to tobacco smoke at home	0.3	0.3	0.5	-0.2	0.7
Birth weight of first child	0.3	0.5	0.6	0.8	-0.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	0.5	0.7	0.6
Gout (self-reported)	0.3	0.4	0.8	-0.9	-0.1
Qualifications: College or University degree	0.3	0.9	1.6	-0.5	-1.3
Emphysema/chronic bronchitis	0.3	0.4	0.5	-0.5	-0.7
Pulse rate, automated reading	0.3	0.9	1.4	-1.2	0.7
Arm fat percentage (left)	0.3	1.0	1.9	1.4	-0.4
Average weekly red wine intake	0.3	0.4	0.7	-0.3	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	0.7	-0.9	0.4
Osteoporosis (self-reported)	0.3	0.3	0.6	0.8	0.2
Medication: Aspirin	0.3	0.4	0.7	-0.0	-0.8
Medication: Gliclazide	0.3	0.3	0.5	0.4	0.7
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.6	0.4	-0.8
Leg fat percentage (left)	0.3	1.1	1.7	1.3	0.6
Average weekly beer plus cider intake	0.3	0.4	0.8	0.9	0.3
Pain experienced in last month	0.3	0.5	0.9	0.0	-1.0
Alzheimer’s Disease (in mother)	0.2	0.2	0.5	-0.7	-0.0
Triglycerides	0.2	0.3	0.5	0.2	0.7
Blood White Count	0.2	1.3	2.4	-0.5	1.6
BMI	0.2	1.1	2.1	1.5	-0.4
Allergy or Eczema	0.2	0.6	0.8	-0.9	0.5
Respiratory disease	0.2	0.5	0.7	-0.6	0.8
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.4	0.6	-0.2
Maternal smoking around birth	0.2	0.4	0.7	-0.0	0.8
Qualifications: CSEs or equivalent	0.2	0.3	0.6	0.1	-0.8
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.5	-0.7	0.5
Number of incorrect matches in round	0.2	0.4	0.5	-0.7	-0.5
Had menopause	0.2	0.3	0.5	-0.7	-0.2
Diabetes (self-reported)	0.2	0.4	0.7	-0.8	-0.2
Medication: Cholesterol lowering	0.2	0.4	0.5	-0.5	-0.7
Impedance of arm (left)	0.2	0.9	1.2	-0.8	1.1
Glaucoma (self-reported)	0.2	0.2	0.3	0.5	-0.4
Body fat percentage	0.2	0.8	1.6	1.3	0.2
Number of full brothers	0.2	0.2	0.4	-0.2	0.6
Shortness of breath walking on level ground	0.2	0.3	0.4	-0.3	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.3	-0.6	-0.4
Overall health rating	0.2	0.3	0.6	-0.3	0.8
Chest pain or discomfort	0.2	0.3	0.6	-0.8	0.2
Age at last live birth	0.2	0.3	0.5	-0.7	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.4	0.6	-0.1
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.3	0.5	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.6	-0.1	-0.8
Mineral and other dietary supplements	0.2	0.3	0.6	0.8	-0.1
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.5	-0.1	0.7
Risk taking	0.2	0.3	0.4	0.6	0.3
Supplements: Calcium	0.2	0.3	0.5	0.7	0.3
Schizophrenia (2018)	0.1	0.2	0.3	0.5	0.3
Worry (Nagel 2018)	0.1	0.3	0.6	-0.8	0.0
Irritable Bowel Disease (IBD)	0.1	0.3	0.4	-0.5	0.6
Ovarian Cancer	0.1	0.1	0.2	0.1	-0.4
Coronary Artery Disease (CAD)	0.1	0.1	0.2	0.5	-0.1
Medication: Metformin	0.1	0.1	0.2	0.3	0.4
Trunk fat percentage	0.1	0.6	1.2	1.1	-0.1
Serious illness, injury or assault to yourself	0.1	0.1	0.1	0.2	0.4
Allergy	0.1	0.2	0.4	0.3	0.6
Pain all over the body in last month	0.1	0.2	0.3	-0.5	0.1
Medication: Simvastatin	0.1	0.2	0.4	-0.6	0.1
Illnesses of siblings	0.1	0.1	0.1	0.3	0.2
Arm fat percentage (right)	0.1	0.6	1.1	1.1	-0.2
Worrier / anxious feelings	0.1	0.2	0.3	0.1	0.6
Pulse rate	0.1	0.1	0.2	-0.5	0.3
Medication: Lansoprazole	0.1	0.2	0.2	0.5	0.3
Pulse wave reflection index	0.1	0.1	0.1	-0.4	0.0
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	0.5	-0.2
High blood pressure (siblings)	0.1	0.2	0.4	0.1	-0.6
Comparative body size at age 10	0.1	0.2	0.4	0.1	-0.7
Number of children fathered	0.1	0.1	0.2	-0.3	0.4
Neck or shoulder pain in last month	0.1	0.1	0.1	-0.3	0.3
Migraine (self-reported)	0.1	0.2	0.2	0.4	-0.5
Supplements: Vitamin C	0.1	0.1	0.2	0.4	0.3
Illnesses of father: Heart disease	0.1	0.2	0.3	0.5	0.2
Loneliness, isolation	0.1	0.2	0.3	-0.6	0.3
Diabetes diagnosed by doctor	0.1	0.2	0.3	0.3	0.5
Qualifications: nursing, teaching	0.1	0.1	0.1	0.4	-0.4
Commuting to job workplace: Walk	0.1	0.1	0.1	0.3	0.3
Number of self-reported non-cancer illnesses	0.1	0.1	0.2	0.4	-0.3
High cholesterol (Self-reported)	0.1	0.2	0.2	-0.3	-0.4
Medication: Lisinopril	0.1	0.1	0.3	0.5	-0.0
Alcohol drinker status: Never	0.1	0.1	0.2	-0.5	0.2
Bipolar Disorder or Schizophrenia	0.0	0.1	0.2	0.0	-0.4
Depression (Nagel 2018)	0.0	0.0	0.0	-0.1	-0.2
Age at First Birth	0.0	0.0	0.1	-0.2	0.0
Crohns Disease (2012)	0.0	0.0	0.0	-0.1	0.1
Lupus	0.0	0.0	0.0	0.2	0.1
Schizophrenia (2014)	0.0	0.1	0.2	0.4	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.1	0.1	-0.4	-0.1
Hearing difficulty/problems with background noise	0.0	0.0	0.0	-0.2	0.2
Happiness	0.0	0.0	0.0	0.1	0.2
Age at first live birth	0.0	0.1	0.1	0.3	0.2
Health satisfaction	0.0	0.1	0.1	-0.3	0.1
Guilty feelings	0.0	0.1	0.1	-0.2	0.3
Age started oral contraceptive pill	0.0	0.0	0.0	-0.0	0.0

Hub : Genes

RAD51L1

Models

Trait associations