[Hub]/) : Traits : Height :

chr17:54,172,277-55,690,000

Best TWAS P=6.63e-41 · Best GWAS P=1.46e-72 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DGKE 0.16 0.15 lasso 12 0.16 1.6e-18 8.0 -13.4 6.6e-41 -0.83 0.33 0.67 TRUE
2 CommonMind Brain Pre-frontal Cortex TRIM25 0.18 0.07 bslmm 474 0.10 1.1e-12 2.6 -7.2 6.8e-13 -0.30 1.00 0.00 TRUE
3 GTEx Adipose Subcutaneous C17orf67 0.15 0.06 lasso 5 0.06 1.3e-05 7.7 -7.3 1.9e-13 -0.57 0.72 0.05 TRUE
4 GTEx Artery Tibial C17orf67 0.11 0.03 lasso 3 0.02 5.1e-03 7.7 -10.8 2.9e-27 -0.62 0.07 0.82 FALSE
5 GTEx Brain Cerebellum RP11-670E13.2 0.40 -0.01 enet 14 0.03 4.3e-02 17.5 9.6 5.6e-22 0.66 0.05 0.60 TRUE
6 GTEx Brain Hypothalamus RP11-670E13.2 0.52 0.14 lasso 10 0.21 9.1e-06 8.4 6.0 1.4e-09 0.41 0.40 0.05 TRUE
7 GTEx Cells EBV-transformed lymphocytes TRIM25 0.30 0.18 lasso 7 0.15 1.0e-05 8.0 7.3 2.4e-13 0.58 0.28 0.23 TRUE
8 GTEx Cells EBV-transformed lymphocytes DGKE 0.35 0.22 lasso 6 0.26 3.6e-09 8.0 7.6 4.1e-14 0.61 0.90 0.08 TRUE
9 GTEx Cells EBV-transformed lymphocytes RP11-670E13.2 0.48 0.18 lasso 10 0.20 4.5e-07 7.7 12.0 2.0e-33 0.79 0.09 0.89 FALSE
10 GTEx Skin Sun Exposed Lower leg C17orf67 0.18 0.08 lasso 5 0.08 2.0e-07 -3.4 -6.8 1.4e-11 -0.42 0.80 0.05 TRUE
11 GTEx Testis RP11-670E13.2 0.22 0.02 lasso 8 0.04 8.3e-03 2.9 9.0 2.8e-19 0.58 0.03 0.69 TRUE
12 GTEx Vagina RP11-670E13.2 0.38 0.00 enet 22 0.05 2.3e-02 5.7 7.3 2.6e-13 0.47 0.11 0.22 FALSE
13 METSIM Adipose DGKE 0.08 0.03 blup 461 0.03 2.7e-05 7.7 -8.7 3.6e-18 -0.47 0.84 0.10 TRUE
14 YFS Blood DGKE 0.02 0.00 blup 444 0.00 4.3e-02 7.7 -10.3 5.2e-25 -0.54 0.15 0.74 TRUE
15 The Cancer Genome Atlas Breast Invasive Carcinoma C17orf67 0.06 0.01 blup 57 0.02 1.2e-05 -3.4 -7.8 4.2e-15 -0.52 0.11 0.40 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma DGKE 0.06 0.00 blup 50 0.02 2.9e-03 2.7 6.0 1.7e-09 0.40 0.02 0.24 FALSE