Best TWAS P=5.75e-15 · Best GWAS P=6.3e-16 conditioned to 2.96e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells EBV-transformed lymphocytes | TAF4B | 0.21 | 0.00 | lasso | 11 | 0.00 | 0.36500 | 7.3 | 7.6 | 2.4e-14 | 0.79 | 0.04 | 0.87 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SS18 | 0.03 | 0.02 | enet | 4 | 0.02 | 0.00015 | -7.0 | 7.2 | 7.6e-13 | 0.19 | 0.13 | 0.77 | TRUE |
3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | SS18 | 0.06 | 0.06 | blup | 42 | 0.04 | 0.00461 | 6.1 | 7.8 | 5.7e-15 | 0.59 | 0.02 | 0.55 | TRUE |