Best TWAS P=3.93e-23 · Best GWAS P=3.39e-25 conditioned to 1.34e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | GALNT1 | 0.12 | 0.14 | lasso | 6 | 0.16 | 1.4e-08 | 9.6 | 9.9 | 3.9e-23 | 0.40 | 0.55 | 0.21 | TRUE |
| 2 | GTEx | Esophagus Mucosa | ZNF24 | 0.14 | 0.02 | enet | 15 | 0.02 | 1.5e-02 | 2.8 | 6.0 | 2.5e-09 | 0.02 | 0.42 | 0.02 | TRUE |
| 3 | METSIM | Adipose | RPRD1A | 0.12 | 0.09 | lasso | 3 | 0.09 | 3.8e-13 | 4.1 | 6.0 | 1.6e-09 | 0.13 | 0.98 | 0.02 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | GALNT1 | 0.03 | 0.02 | lasso | 2 | 0.01 | 3.8e-02 | 7.5 | 7.3 | 2.3e-13 | 0.24 | 0.03 | 0.36 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | INO80C | 0.07 | 0.01 | blup | 56 | 0.02 | 4.2e-03 | -4.4 | 8.0 | 1.4e-15 | 0.56 | 0.14 | 0.55 | TRUE |