Hub : Genes

C21orf119

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0690 0.0240 2.5e-04 0.056 0.038 0.041 0.049 0.047 2.2e-07 1.8e-05 7.6e-06 1.2e-06 1.9e-06
2 GTEx Adipose Subcutaneous 0.0880 0.0390 5.2e-03 0.045 NA 0.026 NA 0.023 1.5e-04 NA 3.1e-03 NA 5.3e-03
3 GTEx Artery Tibial 0.0988 0.0372 2.1e-03 0.057 NA 0.010 NA 0.015 3.0e-05 NA 5.3e-02 NA 2.2e-02
4 GTEx Breast Mammary Tissue 0.2170 0.0690 3.1e-04 0.143 NA 0.063 NA 0.117 8.5e-08 NA 3.7e-04 NA 1.3e-06
5 GTEx Breast Mammary Tissue (Male) 0.2089 0.1319 9.0e-02 0.008 NA 0.010 NA -0.003 2.1e-01 NA 1.8e-01 NA 3.9e-01
6 GTEx Colon Transverse 0.2980 0.0730 3.4e-05 0.138 NA 0.081 NA 0.110 4.1e-07 NA 1.1e-04 NA 6.8e-06
7 GTEx Esophagus Gastroesophageal Junction 0.3230 0.0970 4.6e-04 -0.005 NA 0.034 NA 0.038 5.7e-01 NA 2.3e-02 NA 1.6e-02
8 GTEx Esophagus Mucosa 0.1650 0.0530 7.3e-05 0.087 NA 0.074 NA 0.075 2.0e-06 NA 1.1e-05 NA 9.4e-06
9 GTEx Esophagus Muscularis 0.1190 0.0430 9.5e-04 0.119 NA 0.108 NA 0.113 1.1e-07 NA 4.3e-07 NA 2.3e-07
10 GTEx Muscle Skeletal 0.0670 0.0316 7.2e-03 0.034 NA 0.007 NA 0.020 2.4e-04 NA 5.6e-02 NA 4.4e-03
11 GTEx Nerve Tibial 0.2383 0.0599 5.0e-06 0.120 NA 0.075 NA 0.096 8.0e-09 NA 5.5e-06 NA 2.9e-07
12 GTEx Pancreas 0.1170 0.0500 1.0e-02 0.111 NA 0.078 NA 0.106 2.0e-05 NA 3.3e-04 NA 3.2e-05
13 GTEx Skin Not Sun Exposed Suprapubic 0.1700 0.0680 7.4e-03 0.014 NA 0.019 NA 0.017 5.3e-02 NA 3.1e-02 NA 3.9e-02
14 GTEx Stomach 0.1740 0.0630 1.5e-03 0.111 NA 0.040 NA 0.082 5.8e-06 NA 5.1e-03 NA 9.6e-05
15 GTEx Testis 0.6310 0.0530 0.0e+00 0.651 NA 0.644 NA 0.669 2.8e-37 NA 1.5e-36 NA 5.0e-39
16 GTEx Thyroid 0.2600 0.0540 4.0e-11 0.268 NA 0.271 NA 0.262 1.3e-20 NA 6.8e-21 NA 4.2e-20
17 GTEx Whole Blood 0.0930 0.0410 9.5e-03 0.015 NA 0.041 NA 0.014 1.5e-02 NA 1.2e-04 NA 1.7e-02
18 TCGA Bladder Urothelial Carcinoma 0.0390 0.0240 6.7e-03 0.041 0.017 0.009 NA 0.028 2.2e-04 1.2e-02 5.5e-02 NA 1.7e-03
19 TCGA Breast Invasive Carcinoma 0.0541 0.0190 5.6e-17 0.108 0.091 0.104 NA 0.107 2.3e-21 3.7e-18 1.4e-20 NA 4.7e-21
20 TCGA Colon Adenocarcinoma 0.1870 0.0710 7.1e-08 0.075 0.139 0.143 NA 0.140 4.1e-05 2.1e-08 1.2e-08 NA 1.9e-08
21 TCGA Kidney Renal Clear Cell Carcinoma 0.1444 0.0688 6.8e-09 0.080 0.055 0.043 NA 0.061 2.5e-09 7.4e-07 1.2e-05 NA 2.1e-07
22 TCGA Kidney Renal Papillary Cell Carcinoma 0.0700 0.0380 1.7e-03 0.058 0.032 0.049 NA 0.045 2.9e-04 5.8e-03 8.9e-04 NA 1.3e-03
23 TCGA Lung Adenocarcinoma 0.0418 0.0188 4.8e-06 0.054 0.051 0.051 NA 0.051 6.3e-07 1.1e-06 1.1e-06 NA 1.2e-06
24 TCGA Lung Squamous Cell Carcinoma 0.0652 0.0280 2.2e-08 0.093 0.073 0.075 NA 0.081 9.3e-11 1.0e-08 6.7e-09 NA 1.9e-09
25 TCGA Ovarian Serous Cystadenocarcinoma 0.0770 0.0370 9.6e-05 0.050 0.050 0.051 NA 0.053 2.6e-04 2.7e-04 2.2e-04 NA 1.8e-04
26 TCGA Pancreatic Adenocarcinoma 0.1390 0.0650 4.9e-05 0.077 0.059 0.025 NA 0.043 3.9e-04 1.8e-03 3.1e-02 NA 6.8e-03
27 TCGA Prostate Adenocarcinoma 0.0684 0.0284 8.6e-08 0.085 0.070 0.063 NA 0.078 3.2e-09 7.5e-08 3.4e-07 NA 1.4e-08
28 TCGA Stomach Adenocarcinoma 0.0500 0.0270 7.2e-04 0.077 0.044 0.051 NA 0.068 3.4e-06 3.6e-04 1.3e-04 NA 1.2e-05
29 TCGA Thyroid Carcinoma 0.1510 0.0490 0.0e+00 0.216 0.225 0.218 NA 0.224 9.9e-21 1.2e-21 6.5e-21 NA 1.6e-21

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
Bipolar Disorder (2018) 0.1 0.1 0.7 -0.6 -0.1 -0.3 -0.5 -0.8 0.2 -0.8 -0.3 -0.2 -0.4 -0.1 -0.2 -0.0 0.0 0.2 0.0 0.1 -0.3 -0.3 0.0 -0.1 0.1 -0.1 -0.3 0.1 -0.2 -0.2 -0.3 -0.2
Bipolar Disorder or Schizophrenia 0.1 0.3 2.2 -0.9 -0.4 0.1 -0.7 -1.5 -0.1 -0.1 -0.4 -0.5 -0.6 -0.6 -0.4 -0.3 -0.2 0.3 -0.3 1.5 -0.3 -0.5 0.4 -0.2 -0.3 -0.3 -0.4 -0.3 -0.3 -0.3 -0.5 -0.2
Depressed Affect (Nagel 2018) 0.1 0.2 4.2 0.7 0.1 -0.3 0.1 0.3 -0.6 0.6 0.1 0.1 0.1 0.1 0.1 -2.1 0.1 -0.0 0.1 0.9 0.1 0.1 0.2 0.0 -0.1 0.1 0.2 0.0 0.2 0.1 0.2 0.0
Depression (Nagel 2018) 0.7 1.0 3.6 1.8 0.8 0.8 1.2 1.1 0.6 1.9 1.2 1.0 1.0 0.7 1.0 -0.2 1.1 -1.1 0.8 0.3 1.0 1.1 0.3 1.2 0.9 1.0 1.0 0.9 1.0 1.0 0.9 0.8
Intelligence (Savage-Jansen 2018) 0.1 0.2 1.0 -0.6 -0.4 -0.4 -0.3 -0.9 -1.0 0.3 -0.5 -0.5 -0.4 -0.5 -0.4 0.4 -0.3 0.3 -1.0 -0.3 -0.4 -0.5 -0.5 -0.2 -0.3 -0.4 -0.5 -0.3 -0.2 -0.3 -0.6 -0.3
Neuroticism (Nagel 2018) 0.1 0.3 3.4 0.1 -0.2 -0.7 -0.4 -0.8 -0.4 0.5 -0.1 -0.3 -0.5 -0.3 -0.3 -1.8 -0.4 0.4 -0.5 0.8 -0.3 -0.4 -0.4 -0.4 -0.5 -0.4 -0.2 -0.5 -0.2 -0.3 -0.2 -0.4
Schizophrenia (2018) 0.2 0.3 3.3 -0.7 -0.5 0.3 -0.5 -1.2 -0.3 0.5 -0.4 -0.5 -0.5 -0.7 -0.4 -0.4 -0.3 0.2 -0.4 1.8 -0.2 -0.4 0.7 -0.1 -0.4 -0.2 -0.2 -0.5 -0.2 -0.2 -0.4 -0.0
Schizophrenia vs Biploar Disorder 0.1 0.1 1.6 0.4 0.1 0.3 0.1 0.1 -0.1 1.0 -0.2 0.1 -0.0 -0.1 -0.1 -0.1 -0.2 0.1 -0.0 1.3 -0.2 0.0 0.3 -0.1 0.0 -0.1 0.1 -0.3 0.5 -0.2 -0.0 0.1
Worry (Nagel 2018) 0.1 0.1 1.0 0.3 0.1 0.0 -0.0 -1.0 0.7 0.8 0.4 0.0 -0.1 0.1 0.2 -0.9 0.3 -0.3 0.0 0.2 0.4 0.1 -0.0 0.3 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.2
Alzheimer’s Disease (in mother) 0.4 0.5 1.9 0.4 0.7 0.7 0.4 0.5 0.5 -0.1 0.6 0.6 0.5 0.8 0.6 1.4 0.7 -0.6 0.7 1.4 0.7 0.5 1.0 0.7 0.3 0.7 0.6 0.6 0.9 0.7 0.5 0.7
Alzheimer’s Disease (in father) 0.1 0.1 1.6 0.2 0.1 0.2 -0.1 -0.2 -0.0 -0.5 0.0 0.1 0.1 0.2 0.2 -0.9 0.2 -0.3 0.1 -0.5 0.2 0.2 1.3 0.1 0.3 0.1 0.3 -0.1 -0.1 0.2 0.1 0.6
Alzheimer’s Disease (including proxy) 0.3 0.5 2.6 0.4 0.7 0.6 0.3 0.2 0.4 -0.2 0.6 0.5 0.4 0.8 0.6 0.6 0.7 -0.6 0.7 1.0 0.8 0.5 1.6 0.5 0.4 0.6 0.8 0.5 0.8 0.7 0.5 0.9
Crohns Disease (2017) 0.9 2.0 4.2 -1.4 -1.3 -1.5 -1.2 -0.4 -1.1 -0.3 -1.6 -1.4 -1.4 -1.4 -1.5 -0.3 -1.6 1.6 -1.3 1.5 -1.5 -1.5 -2.0 -1.5 -1.6 -1.5 -1.5 -1.4 -1.1 -1.5 -1.5 -1.7
Irritable Bowel Disease (IBD) 0.5 1.1 7.2 -0.8 -0.7 -0.8 -0.7 0.5 -0.5 0.9 -1.2 -0.9 -0.8 -1.0 -1.0 -0.2 -1.2 1.2 -0.6 2.7 -1.1 -0.9 -1.4 -1.1 -1.0 -1.0 -1.0 -0.9 -0.4 -1.2 -0.9 -1.2
Ulcerative Colitis (UC) 0.2 0.4 4.3 0.3 0.5 0.5 0.4 1.5 0.5 1.5 -0.1 0.3 0.4 0.2 0.1 -0.1 -0.0 0.0 0.6 2.1 -0.1 0.3 0.3 0.1 0.2 0.2 0.3 0.3 0.7 -0.0 0.3 0.2
Major Depression (MDD) 0.5 0.6 1.5 1.1 0.9 0.4 0.7 0.4 0.6 1.2 0.6 0.8 0.7 0.9 0.8 0.7 0.8 -0.6 0.6 0.4 0.7 0.7 0.8 0.6 1.0 0.8 0.7 0.4 0.7 0.7 0.7 0.9
Reaction Time 0.0 0.1 0.7 -0.1 -0.0 -0.1 -0.1 0.1 0.2 -0.9 0.2 -0.0 -0.1 -0.0 0.0 -0.2 0.3 -0.1 0.1 -0.8 0.1 -0.1 -0.6 0.3 -0.2 0.1 -0.2 0.0 -0.3 0.1 -0.0 -0.2
Verbal and Numeric Reasoning (VNR) 0.0 0.1 1.2 0.1 0.0 -0.0 0.1 -1.1 -0.4 0.8 0.1 0.0 0.1 -0.0 0.1 -0.1 0.1 -0.2 -0.6 -0.5 0.2 0.1 0.4 0.2 0.0 0.1 0.2 0.1 0.2 0.2 0.1 0.2
Breast Cancer 0.3 0.7 2.8 -1.7 -0.5 -0.4 -0.6 0.1 -0.9 -1.2 -0.9 -0.7 -0.5 -0.8 -0.8 1.3 -0.9 1.0 0.2 0.5 -0.9 -0.7 -1.0 -1.0 -1.1 -0.9 -0.7 0.0 -1.1 -1.0 -0.6 -0.9
Ovarian Cancer 0.7 0.9 4.1 1.0 0.8 1.1 0.6 1.2 0.2 1.2 0.6 0.6 0.5 0.4 0.8 -0.9 0.9 -0.9 0.7 2.0 0.8 0.7 1.7 0.9 0.8 0.9 0.9 0.5 1.7 0.9 0.6 1.1
Prostate Cancer 0.1 0.1 0.8 -0.2 0.1 0.3 -0.0 0.2 0.1 -0.9 0.1 -0.0 0.1 0.1 0.1 0.4 0.2 -0.2 0.7 0.2 0.2 0.1 0.0 0.2 0.3 0.1 -0.1 0.1 0.5 0.2 -0.0 0.1
Age at First Birth 0.4 0.6 1.2 1.1 0.9 0.3 1.0 0.1 0.6 0.9 0.9 1.0 0.9 1.0 0.9 -1.0 0.8 -0.8 0.8 -0.3 0.9 0.7 0.3 0.9 0.7 0.8 0.7 0.9 0.9 0.8 0.7 0.6
Bipolar Disorder (2011) 0.2 0.2 0.5 0.2 0.4 0.7 0.4 0.6 0.0 -0.0 0.2 0.4 0.3 0.5 0.4 0.1 0.7 -0.5 0.7 0.6 0.5 0.4 -0.3 0.7 0.5 0.6 0.4 0.3 0.6 0.5 0.5 0.2
Body Mass Index (BMI) (2010) 0.9 1.3 5.9 0.7 1.0 0.9 1.1 0.9 1.7 1.2 1.1 1.0 1.2 0.8 0.9 2.4 0.9 -0.9 1.3 -1.5 0.8 1.1 1.2 0.8 0.8 0.9 1.1 1.4 0.7 0.9 1.0 1.0
Coronary Artery Disease (CAD) 0.9 1.1 2.2 -1.4 -0.8 -1.1 -1.5 -1.5 -0.8 -1.3 -1.1 -0.9 -1.3 -0.6 -1.1 -1.2 -1.1 0.9 -0.4 0.2 -1.3 -1.2 -0.2 -0.9 -0.7 -1.0 -1.2 -1.0 -0.9 -1.1 -1.3 -0.8
Crohns Disease (2012) 0.2 0.3 1.4 -0.8 -0.4 -0.6 -0.4 -0.8 -0.2 -0.1 -0.4 -0.5 -0.5 -0.4 -0.4 -0.1 -0.6 0.6 -0.4 1.2 -0.4 -0.5 -0.6 -0.6 -0.7 -0.5 -0.5 -0.2 -0.3 -0.5 -0.5 -0.7
Mean Putamen Volume 0.3 0.3 2.0 -1.0 -0.5 -0.5 -0.7 -1.4 -0.1 -1.4 -0.5 -0.5 -0.5 -0.4 -0.4 -0.8 -0.3 0.4 -0.4 -0.2 -0.4 -0.5 0.8 -0.3 -0.4 -0.4 -0.2 0.1 -0.3 -0.4 -0.5 -0.2
Fasting Glucose 0.2 0.2 2.9 -0.1 -0.2 -0.1 -0.6 -0.2 -0.4 -0.4 -0.5 -0.5 -0.4 -0.4 -0.5 0.2 -0.3 0.4 -0.3 1.7 -0.5 -0.4 0.2 -0.5 -0.6 -0.4 -0.3 -0.2 -0.1 -0.4 -0.5 -0.4
HbA1C 2.1 2.4 4.6 -1.2 -1.1 -1.4 -2.0 -2.2 -0.8 -1.8 -1.4 -1.1 -1.9 -0.8 -1.4 -2.0 -1.6 1.6 -1.6 0.6 -1.7 -1.4 -1.4 -1.6 -1.7 -1.4 -1.4 -2.0 -1.7 -1.7 -1.2 -1.7
HDL Cholesterol 0.3 0.6 1.2 0.6 0.6 1.1 0.5 1.1 0.6 -0.5 0.9 0.7 0.6 1.0 0.7 0.0 0.9 -0.8 0.8 -1.0 0.8 0.6 0.6 0.9 0.8 0.8 0.6 0.6 0.2 0.8 0.6 0.8
LDL Cholesterol 4.6 7.2 9.3 -2.7 -2.9 -2.8 -2.5 -2.1 -2.4 -2.3 -2.9 -2.8 -2.6 -2.6 -2.9 -1.4 -3.0 3.0 -2.5 -0.1 -3.0 -2.7 -2.8 -3.0 -3.0 -3.0 -2.9 -2.6 -2.9 -3.0 -2.8 -3.0
Lupus 0.4 0.5 2.4 -0.2 -1.0 -0.2 -0.8 -0.3 -1.1 -0.3 -0.6 -0.9 -0.8 -0.9 -0.7 -1.6 -0.2 0.3 -0.7 1.0 -0.5 -0.9 -0.0 -0.2 -0.6 -0.4 -0.8 -1.3 -0.3 -0.4 -1.0 -0.6
Neuroticism (2016) 4.1 5.9 8.5 -2.4 -2.6 -2.1 -2.6 -2.9 -2.1 -2.5 -2.5 -2.6 -2.6 -2.6 -2.5 -2.9 -2.4 2.4 -2.4 -0.4 -2.4 -2.5 -1.9 -2.5 -2.5 -2.5 -2.4 -2.2 -2.4 -2.4 -2.4 -2.4
Primary Biliary Cirrhosis 0.1 0.1 0.7 -0.1 0.3 0.4 0.2 0.3 0.5 -0.6 0.2 0.2 0.2 0.2 0.2 -0.7 0.1 -0.2 0.3 0.3 0.3 0.2 0.7 0.1 0.2 0.2 0.3 0.3 0.8 0.2 0.2 0.2
Rheumatoid Arthritis 0.4 0.5 3.2 -0.9 -0.4 -0.5 -0.7 -0.7 -0.9 0.2 -0.6 -0.6 -0.6 -0.8 -0.6 -1.2 -0.7 0.7 -0.5 1.8 -0.6 -0.5 -0.2 -0.8 -0.6 -0.6 -0.5 -0.5 -0.4 -0.6 -0.6 -0.5
Schizophrenia (2014) 0.4 0.9 6.9 -1.2 -0.9 -0.4 -1.2 -1.0 -0.6 0.3 -1.0 -1.0 -0.9 -1.2 -0.8 -0.9 -0.7 0.7 -0.5 2.6 -0.7 -0.9 1.0 -0.7 -0.8 -0.7 -0.7 -0.8 -0.3 -0.7 -0.9 -0.4
Triglycerides 0.5 0.8 2.8 -0.8 -0.8 -1.1 -0.6 -1.0 -0.6 -0.3 -0.8 -0.8 -0.8 -0.8 -0.8 0.0 -1.0 1.1 -0.4 -0.1 -0.8 -0.8 -1.7 -1.0 -1.1 -0.9 -1.0 -0.6 -0.5 -0.9 -0.8 -1.3
Type 2 Diabetes (T2D) (2012) 2.1 2.4 4.2 -1.9 -1.7 -1.1 -2.0 -1.2 -1.2 -1.4 -1.8 -1.8 -1.9 -1.6 -1.8 -0.8 -1.8 1.5 -1.0 0.8 -1.8 -1.8 -1.0 -1.3 -1.6 -1.7 -1.7 -1.7 -1.2 -1.7 -1.8 -1.6
Ulcerative Colitis 0.9 1.3 3.1 1.1 1.3 1.2 1.3 1.5 1.2 1.7 0.7 1.1 1.3 1.0 0.9 0.1 0.7 -0.8 1.5 1.8 0.8 1.2 1.0 0.8 1.0 0.9 1.2 1.1 1.5 0.8 1.1 1.0
Blood Eosinophil Count 0.2 1.9 6.1 1.0 1.2 0.8 1.3 1.7 1.9 1.4 1.2 1.2 1.3 1.2 1.2 2.5 1.2 -1.2 1.4 -2.1 1.2 1.2 1.2 1.2 1.2 1.1 1.3 1.7 0.9 1.2 1.2 1.4
Blood Platelet Count 0.1 0.6 1.4 -0.9 -0.8 -0.8 -0.9 -1.2 -1.1 0.9 -0.9 -0.9 -0.8 -0.8 -0.8 -0.1 -0.7 0.6 -0.7 0.5 -0.7 -0.8 -0.3 -0.8 -0.7 -0.8 -0.7 -0.7 -0.8 -0.7 -0.8 -0.6
Blood Red Count 0.0 0.1 0.6 0.1 0.1 -0.0 0.1 0.8 0.2 -0.7 -0.3 -0.0 -0.0 0.3 0.0 0.4 -0.1 0.0 0.3 0.7 0.1 -0.0 0.1 -0.1 0.0 -0.0 0.1 -0.2 0.3 0.0 -0.0 0.0
Blood White Count 0.3 2.4 5.1 -1.9 -1.5 -1.4 -1.4 -1.3 -1.5 -2.3 -1.9 -1.6 -1.6 -1.5 -1.7 -1.8 -1.5 1.5 -1.0 -0.4 -1.6 -1.6 -1.3 -1.4 -1.5 -1.6 -1.5 -1.4 -1.3 -1.6 -1.7 -1.5
Heel T-Score 0.6 4.4 6.2 2.3 2.3 2.2 1.8 2.4 1.8 1.6 1.9 2.1 2.1 2.2 2.1 1.9 2.5 -2.3 1.9 1.2 2.0 2.1 2.1 2.3 2.2 2.4 2.1 1.9 2.5 2.1 2.1 2.3
BMI 0.2 1.1 2.9 -0.6 -1.0 -1.0 -1.0 -0.3 -1.5 -0.5 -1.3 -1.1 -1.1 -1.4 -1.1 -1.7 -0.9 0.9 -1.2 -0.1 -1.1 -1.1 -1.0 -0.8 -0.9 -1.0 -1.0 -1.4 -0.4 -1.1 -1.1 -0.9
Height 0.4 8.3 35.3 1.6 2.3 2.6 2.8 2.1 2.6 2.4 2.8 2.7 2.7 3.1 2.8 2.2 3.1 -3.1 3.3 -5.9 2.8 2.8 1.2 3.1 3.3 2.7 2.6 3.4 1.4 2.9 2.7 2.8
Waist Hip Ratio (WHR) 0.8 3.7 6.9 -2.1 -2.1 -1.9 -1.8 -2.0 -1.7 -2.6 -1.7 -2.0 -1.9 -1.8 -1.8 -1.9 -1.7 1.7 -1.6 -2.5 -1.7 -1.9 -2.1 -1.7 -1.8 -1.9 -2.0 -1.5 -2.4 -1.7 -2.0 -1.9
Systolic Blood Pressure 0.3 1.6 9.8 0.4 0.9 1.1 0.9 2.1 0.7 -1.0 0.8 0.8 0.9 1.2 0.9 1.3 1.5 -1.3 2.0 -3.1 1.0 0.9 0.2 1.5 1.1 1.1 0.8 1.5 0.5 1.1 0.8 1.1
Smoking Status 0.1 0.3 1.3 0.7 0.4 0.3 0.4 1.0 1.2 -0.5 0.4 0.5 0.5 0.4 0.4 0.7 0.3 -0.4 1.0 0.3 0.4 0.4 1.1 0.2 0.6 0.4 0.6 0.1 0.6 0.4 0.4 0.6
Allergy or Eczema 0.1 0.3 3.6 0.3 0.2 0.3 0.0 0.5 -1.0 0.6 -0.0 0.0 0.0 0.1 0.0 -0.8 0.2 -0.2 0.4 1.9 0.1 0.0 0.5 0.2 0.2 0.2 0.2 -0.3 0.7 0.1 0.0 0.3
Cardiovascular Disease 0.4 1.3 3.2 1.1 1.0 1.0 1.0 0.7 0.5 0.4 1.1 1.0 1.0 1.1 1.1 0.6 1.4 -1.4 1.4 -1.8 1.3 1.1 1.1 1.5 1.0 1.2 1.2 1.0 1.1 1.3 1.0 1.3
Hypothyroidism (self reported) 0.2 0.4 3.5 0.3 0.5 0.0 0.3 0.6 0.0 -0.6 0.4 0.5 0.4 0.8 0.5 -0.4 0.5 -0.5 0.8 -1.9 0.5 0.5 0.7 0.5 0.7 0.4 0.5 0.8 0.4 0.5 0.4 0.7
Respiratory disease 0.0 0.1 0.5 -0.6 0.1 0.3 0.1 0.4 0.3 0.3 -0.0 0.1 0.1 0.0 -0.0 0.7 -0.2 0.1 0.6 -0.4 -0.1 0.0 0.1 -0.2 0.3 -0.1 -0.0 0.4 -0.3 -0.2 0.1 0.0
Type 2 Diabetes (T2D) (2018) 0.0 0.1 0.4 -0.6 -0.2 -0.3 -0.3 0.0 -0.2 -0.6 -0.1 -0.2 -0.2 -0.2 -0.2 0.3 -0.2 0.2 -0.2 -0.3 -0.1 -0.2 0.3 -0.3 -0.3 -0.2 -0.1 0.0 -0.4 -0.1 -0.2 -0.0
Lung FEV1/FVC ratio 0.1 0.6 4.6 1.5 0.5 0.4 0.5 0.6 -0.0 -0.3 0.0 0.4 0.5 0.2 0.4 0.0 0.5 -0.5 -0.4 2.2 0.4 0.4 1.3 0.6 0.5 0.6 0.6 -0.8 1.5 0.4 0.4 0.6
Lung FVC 1.2 6.3 9.0 3.0 2.9 1.9 2.6 1.8 1.7 1.5 2.7 2.7 2.7 2.8 2.7 1.1 2.6 -2.6 2.4 1.4 2.7 2.6 2.6 2.6 2.6 2.7 2.8 2.4 3.0 2.6 2.7 2.7
Neuroticism 0.3 0.6 4.1 -0.3 -0.9 -0.8 -0.8 -0.9 -1.0 0.3 -0.5 -0.9 -0.9 -0.9 -0.7 -2.0 -0.5 0.6 -0.6 0.3 -0.6 -0.8 -0.7 -0.5 -1.0 -0.7 -0.7 -0.8 -0.7 -0.6 -0.8 -0.8
Chronotype (morning person) 0.1 0.2 1.3 -0.4 -0.4 0.0 -0.5 -0.2 -0.2 -0.2 -0.3 -0.3 -0.4 -0.3 -0.4 0.9 -0.5 0.6 -0.8 -1.2 -0.5 -0.4 -0.2 -0.5 -0.4 -0.5 -0.3 -0.1 -0.9 -0.5 -0.4 -0.4
Hair Pigment 0.1 2.8 5.5 -1.3 -1.8 -1.3 -2.2 -1.5 -2.1 -1.2 -1.8 -1.8 -1.9 -2.0 -1.8 -1.3 -1.4 1.5 -2.1 2.2 -1.7 -1.7 0.5 -1.5 -1.4 -1.5 -1.5 -2.3 -0.7 -1.6 -1.8 -1.2
Tanning 0.1 1.2 2.7 1.1 1.2 0.6 1.0 1.2 0.5 0.9 1.3 1.2 1.1 0.9 1.1 1.5 1.2 -1.2 0.7 0.4 1.1 1.1 1.7 1.1 1.1 1.2 1.3 0.9 1.2 1.1 1.1 1.2
Hand grip strength (left) 0.4 1.1 2.9 0.2 1.1 0.7 1.0 0.3 1.4 1.0 1.1 1.0 1.1 0.7 1.0 1.6 1.1 -1.1 0.8 -1.7 1.0 1.1 0.5 1.0 1.1 1.0 1.1 1.5 0.6 1.0 1.2 1.1
Number of treatments/medications taken 0.2 0.3 1.2 0.4 0.3 0.7 0.3 0.5 0.5 -0.5 0.5 0.3 0.3 0.6 0.3 0.5 0.5 -0.5 0.9 -1.1 0.3 0.4 0.8 0.5 0.6 0.4 0.5 0.6 0.4 0.4 0.3 0.6
Average weekly spirits intake 0.4 0.5 4.9 -0.6 -0.7 -0.3 -0.6 -0.1 -1.1 -1.3 -0.7 -0.5 -0.6 -0.5 -0.6 0.0 -0.6 0.5 -0.7 -2.2 -0.6 -0.5 -0.1 -0.6 0.0 -0.7 -0.6 -0.3 -0.7 -0.6 -0.6 -0.3
Sensitivity / hurt feelings 1.0 1.8 3.2 -1.0 -1.4 -1.2 -1.5 -1.2 -1.5 -1.0 -1.2 -1.5 -1.5 -1.6 -1.4 -1.1 -1.2 1.2 -1.6 1.8 -1.3 -1.5 -0.9 -1.2 -1.3 -1.2 -1.4 -1.6 -0.8 -1.2 -1.5 -1.3
Frequency of depressed mood in last 2 weeks 0.2 0.2 2.3 0.7 -0.0 -0.6 0.0 -0.2 -0.5 1.1 -0.2 -0.1 -0.1 -0.2 -0.1 -1.1 -0.0 0.0 -0.2 1.5 -0.1 -0.1 0.3 0.0 -0.1 -0.0 0.1 -0.6 0.3 -0.1 -0.1 0.0
Hearing difficulty/problems: Yes 0.1 0.1 0.3 -0.5 -0.4 -0.1 -0.4 -0.5 -0.2 -0.4 -0.1 -0.3 -0.3 -0.6 -0.3 0.1 -0.2 0.2 -0.4 -0.5 -0.3 -0.2 -0.1 -0.3 -0.1 -0.2 -0.3 0.2 -0.4 -0.3 -0.2 -0.3
Relative age of first facial hair 0.9 1.9 3.2 1.4 1.4 1.4 1.7 0.7 1.3 0.2 1.4 1.5 1.5 1.5 1.5 -0.6 1.4 -1.4 1.8 -0.7 1.4 1.4 1.4 1.4 1.5 1.4 1.6 1.4 1.2 1.4 1.5 1.5
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 1.3 0.4 0.2 0.7 0.5 -0.0 -0.5 0.1 0.2 0.4 0.3 0.3 0.4 -1.1 0.7 -0.7 0.6 -0.1 0.5 0.4 0.6 0.8 0.8 0.6 0.4 0.4 0.6 0.5 0.3 0.8
Ever used hormone-replacement therapy (HRT) 0.1 0.2 0.7 0.7 0.2 0.1 0.3 0.8 -0.1 0.3 0.2 0.3 0.3 0.5 0.3 0.4 0.4 -0.3 0.6 0.4 0.3 0.2 0.8 0.4 0.3 0.4 0.3 0.1 0.3 0.3 0.2 0.4
Ever had hysterectomy (womb removed) 0.5 0.5 0.9 -0.8 -0.8 -0.5 -0.6 -0.1 -1.0 -0.2 -0.8 -0.7 -0.7 -0.6 -0.8 -0.2 -0.9 0.9 -0.7 -0.9 -0.9 -0.8 -0.5 -0.8 -0.8 -0.9 -0.7 -0.7 -0.9 -0.9 -0.7 -0.7
Systolic blood pressure, automated reading 0.6 1.8 5.1 1.0 1.2 1.3 1.1 2.3 1.2 -0.6 1.0 1.1 1.1 1.3 1.1 1.6 1.5 -1.4 1.8 -1.9 1.1 1.1 1.1 1.5 1.6 1.2 1.1 1.3 1.0 1.2 1.0 1.5
Eye problems/disorders: Diabetes related eye disease 0.7 0.8 1.9 -0.3 -1.0 -0.9 -0.7 -0.4 -1.1 -0.9 -1.1 -0.9 -0.9 -0.9 -0.9 -0.9 -0.7 0.8 -1.0 1.0 -0.9 -1.0 -1.0 -0.6 -0.8 -0.7 -0.9 -1.4 -0.5 -0.8 -0.9 -0.9
Angina 0.1 0.1 0.4 0.2 -0.3 0.1 -0.3 -0.6 -0.0 -0.0 -0.3 -0.3 -0.2 -0.3 -0.3 0.3 -0.2 0.3 -0.5 -0.5 -0.3 -0.2 0.3 -0.2 -0.4 -0.2 -0.2 -0.6 -0.4 -0.3 -0.3 -0.1
Medication for hormone replacement therapy 8.1 9.1 12.2 -3.3 -3.2 -2.7 -3.3 -2.9 -3.3 -2.7 -3.2 -3.1 -3.1 -3.0 -3.2 -2.0 -3.3 3.4 -2.7 1.2 -3.2 -3.2 -1.5 -3.5 -3.1 -3.2 -3.0 -3.1 -3.0 -3.3 -3.1 -3.1
Vitamin and mineral supplements 0.5 0.7 2.2 0.8 0.7 0.3 0.5 1.3 1.5 0.7 0.6 0.8 0.8 0.8 0.8 1.3 0.6 -0.7 0.8 -1.0 0.7 0.8 0.8 0.5 1.1 0.7 0.6 0.6 0.2 0.7 0.8 0.8
Supplements: Zinc 0.1 0.1 0.6 -0.2 -0.0 0.4 0.0 -0.2 0.3 0.1 0.1 -0.0 -0.0 0.2 -0.0 0.4 0.1 0.0 0.7 -0.8 0.0 -0.1 -0.3 0.1 -0.3 0.0 -0.0 0.1 -0.1 0.0 -0.1 -0.2
Medication: Co-codamol 0.2 0.3 2.2 0.1 0.4 0.5 0.2 0.8 0.1 1.1 0.2 0.3 0.3 0.5 0.2 1.1 0.5 -0.4 0.6 1.5 0.2 0.3 -0.0 0.5 0.3 0.5 0.2 0.2 0.5 0.3 0.3 0.3
Medication: Metformin 0.1 0.2 2.0 -0.1 0.3 0.4 0.2 0.0 0.4 0.2 0.5 0.3 0.3 0.1 0.4 1.4 0.3 -0.3 -0.0 0.0 0.4 0.3 0.5 0.2 0.2 0.3 0.3 0.4 0.2 0.4 0.3 0.4
Diabetes (father) 0.6 0.7 1.7 -0.9 -0.6 -0.7 -0.7 -0.4 -0.6 -0.1 -0.8 -0.6 -0.6 -0.6 -0.8 -1.2 -0.9 1.1 -0.8 0.6 -0.9 -0.7 -1.2 -1.0 -1.3 -0.8 -0.8 -0.4 -1.1 -0.9 -0.6 -1.2
Diabetes (mother) 0.3 0.4 2.3 1.0 0.5 0.9 1.0 1.5 0.4 -0.2 0.4 0.6 0.7 0.8 0.5 0.8 0.2 -0.4 0.5 -0.5 0.4 0.6 -0.7 0.4 0.3 0.4 0.6 -0.1 0.5 0.3 0.7 0.2
Severe depression (siblings) 0.1 0.1 0.8 0.1 -0.4 -0.2 -0.3 -0.4 0.0 -0.3 -0.2 -0.2 -0.3 -0.1 -0.2 -0.9 -0.1 0.2 -0.4 -0.0 -0.2 -0.3 0.3 -0.2 -0.1 -0.2 -0.2 -0.5 -0.1 -0.2 -0.3 -0.2
Pack years adult smoking proportion 0.7 1.0 3.2 -0.9 -0.9 -1.1 -1.1 -1.1 -0.8 -0.3 -0.9 -1.0 -1.0 -1.4 -0.9 -0.0 -1.0 1.0 -1.3 1.8 -0.9 -1.0 -0.6 -1.0 -0.9 -0.9 -1.1 -1.3 -0.7 -0.9 -1.1 -1.0
Impedance of leg (right) 0.2 1.2 19.4 -1.3 0.0 0.2 0.3 -0.4 0.6 -1.9 0.4 0.2 0.2 0.8 0.3 0.2 0.2 -0.2 1.2 -4.4 0.3 0.2 -0.8 0.2 0.4 -0.1 0.1 1.6 -1.3 0.3 0.3 0.1
Leg fat-free mass (left) 0.0 0.2 2.7 0.7 0.0 0.1 0.1 0.3 0.0 1.6 -0.0 0.1 -0.0 -0.4 0.1 -0.3 0.4 -0.4 -0.3 0.3 0.1 0.1 -0.0 0.4 0.3 0.3 0.1 -0.6 0.7 0.2 0.0 0.2
Trunk fat percentage 0.2 0.8 4.2 -0.3 -1.1 -0.9 -0.5 -0.3 -0.7 -0.6 -0.8 -0.8 -0.8 -0.7 -0.8 -1.8 -0.5 0.5 -0.8 -2.0 -0.8 -0.8 -1.3 -0.4 -0.2 -0.7 -0.9 -1.0 -0.7 -0.7 -0.9 -0.7
Hand grip strength (right) 0.0 0.1 1.8 -0.6 -0.1 -0.4 -0.2 -0.2 0.6 -0.0 0.1 -0.1 -0.1 -0.3 -0.1 0.4 0.0 -0.1 -0.1 -1.3 -0.0 0.0 0.3 0.0 0.0 -0.1 0.1 0.2 -0.2 0.0 0.0 0.2
Townsend deprivation index at recruitment 1.0 1.4 2.1 -1.2 -1.3 -1.3 -1.4 -0.4 -0.7 -1.2 -1.4 -1.3 -1.3 -1.0 -1.3 -1.3 -1.1 1.1 -1.1 1.5 -1.2 -1.3 -0.6 -1.1 -1.4 -1.0 -1.3 -1.3 -0.8 -1.2 -1.3 -1.2
Current tobacco smoking 0.6 0.9 3.2 1.5 0.9 1.2 0.9 0.8 1.0 0.4 0.7 0.9 1.0 0.7 0.9 -0.3 0.7 -0.8 0.8 1.3 0.8 1.0 1.8 0.7 0.9 0.9 1.1 0.2 1.3 0.8 1.0 1.1
Average weekly fortified wine intake 1.1 1.3 5.7 1.4 1.1 1.1 0.8 2.0 0.7 1.7 0.9 1.0 1.0 0.8 1.0 -0.4 0.9 -0.9 1.0 2.4 1.0 1.0 1.1 0.8 1.0 1.0 1.0 0.6 1.1 0.9 1.0 1.0
Maternal smoking around birth 1.9 2.7 4.3 -1.9 -1.7 -1.7 -1.6 -1.6 -1.5 -2.1 -1.6 -1.6 -1.6 -1.6 -1.7 -0.2 -1.9 1.8 -1.3 -1.0 -1.8 -1.6 -1.3 -1.9 -1.7 -1.8 -1.6 -1.4 -1.7 -1.8 -1.6 -1.7
Fed-up feelings 2.0 3.6 12.1 -1.4 -1.9 -2.2 -1.9 -2.0 -2.1 -1.8 -1.8 -1.9 -1.9 -2.0 -1.9 -3.5 -1.8 1.8 -2.0 0.7 -1.8 -1.9 -0.8 -1.8 -2.2 -1.8 -1.7 -1.9 -1.4 -1.8 -1.9 -1.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.0 2.6 1.6 1.1 0.7 1.2 1.0 0.5 0.6 1.1 1.1 1.1 1.0 1.1 -0.4 1.1 -1.1 1.0 0.2 1.0 1.0 0.8 1.2 1.1 1.1 1.1 0.8 1.3 1.1 1.1 1.0
Relative age voice broke 1.3 1.9 2.9 0.8 1.4 1.4 1.4 0.7 1.5 0.6 1.5 1.3 1.3 1.5 1.5 0.9 1.6 -1.5 1.7 -1.3 1.6 1.3 0.9 1.6 1.6 1.4 1.4 1.7 1.5 1.6 1.4 1.4
Taking other prescription medications 0.4 0.6 6.6 -0.1 0.3 0.8 0.3 1.1 0.5 -0.7 0.4 0.4 0.3 0.7 0.5 -0.4 0.7 -0.7 1.1 -2.6 0.5 0.4 1.0 0.7 0.9 0.5 0.5 0.8 0.2 0.6 0.4 0.7
Age when periods started (menarche) 0.6 1.4 2.7 -1.2 -1.3 -0.9 -1.0 -0.3 -1.3 -1.4 -1.3 -1.2 -1.1 -1.6 -1.3 -1.0 -1.6 1.5 -0.7 -0.6 -1.4 -1.1 -0.8 -1.5 -1.1 -1.4 -1.1 -0.9 -0.9 -1.5 -1.1 -1.2
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 3.1 -0.7 -0.9 -0.4 -0.5 0.5 -0.7 -0.6 -1.0 -0.6 -0.6 -0.4 -0.9 -0.9 -0.9 0.9 -0.2 -1.8 -1.0 -0.7 -0.8 -0.8 -0.6 -0.9 -0.7 -0.6 -1.1 -1.0 -0.7 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.9 2.0 1.3 0.9 1.0 0.7 1.4 0.5 0.8 0.9 0.9 0.8 0.8 1.0 1.1 1.1 -1.0 0.4 0.1 1.1 0.9 1.2 1.1 0.9 1.1 1.0 0.5 1.2 1.1 0.9 1.0
Tinnitus: Yes, but not now, but have in the past 0.8 0.8 1.6 -1.3 -0.9 -1.2 -0.9 0.1 -0.5 -1.1 -1.1 -0.8 -0.8 -0.8 -0.9 -0.7 -1.2 1.1 -0.5 -0.1 -1.0 -0.9 0.0 -1.2 -1.1 -1.0 -0.8 -0.5 -0.8 -1.1 -0.9 -1.0
Qualifications: CSEs or equivalent 0.1 0.1 1.0 0.9 0.1 0.2 0.4 -0.3 -0.1 1.0 0.5 0.3 0.2 0.3 0.3 -0.1 0.2 -0.3 -0.0 -0.2 0.4 0.3 -0.8 0.3 0.1 0.2 0.1 -0.1 -0.1 0.3 0.3 0.0
Serious illness, injury or assault to yourself 0.5 0.6 3.1 -0.6 -0.9 -0.6 -0.6 -0.4 -0.8 -0.4 -0.6 -0.7 -0.7 -0.5 -0.7 -0.8 -0.6 0.6 -0.5 -1.8 -0.7 -0.7 -0.7 -0.5 -0.8 -0.7 -0.6 -0.8 -1.4 -0.7 -0.7 -0.6
High blood pressure 0.0 0.1 0.6 0.4 0.1 0.1 0.1 -0.1 0.4 -0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.3 -0.3 0.5 -0.8 0.1 0.1 0.5 0.3 -0.0 0.2 0.2 0.1 0.1 0.2 0.1 0.2
Hayfever, allergic rhinitis or eczema 0.2 0.3 4.2 0.5 0.2 0.5 0.1 -0.2 -0.9 -0.0 0.1 0.1 0.0 0.3 0.2 -1.1 0.6 -0.4 0.2 2.1 0.3 0.1 0.6 0.6 0.4 0.4 0.2 -0.4 0.9 0.3 0.0 0.4
Multivitamins +/- minerals 0.6 0.7 1.8 -1.0 -0.7 -0.4 -0.6 -0.9 -1.4 -0.9 -0.7 -0.8 -0.8 -0.6 -0.8 -1.2 -0.9 0.9 -0.6 0.8 -0.8 -0.9 -0.7 -0.8 -1.3 -0.9 -0.7 -0.8 -0.6 -0.8 -0.8 -0.9
Stomach or abdominal pain in last month 4.4 5.4 9.0 -3.0 -2.7 -2.3 -2.8 -2.5 -2.0 -1.3 -2.4 -2.7 -2.7 -2.8 -2.6 -1.8 -2.3 2.3 -2.2 -0.3 -2.5 -2.6 -1.4 -2.3 -2.1 -2.5 -2.5 -2.0 -2.2 -2.4 -2.7 -2.2
Supplements: Glucosamine 0.1 0.2 4.4 0.2 -0.1 -0.1 -0.3 0.1 -0.3 0.1 0.1 -0.2 -0.2 0.1 -0.1 -0.4 0.1 0.0 -0.2 2.1 0.1 -0.3 0.2 -0.0 -0.3 0.0 -0.2 -0.5 0.1 0.1 -0.2 -0.1
Diverticular disease/diverticulitis (self-reported) 7.1 8.4 10.6 -2.5 -2.9 -3.0 -3.1 -2.8 -2.4 -1.1 -3.1 -3.1 -3.2 -3.2 -3.1 -2.6 -3.1 3.1 -3.1 2.8 -3.0 -3.2 -2.0 -3.1 -2.9 -3.0 -3.0 -3.3 -2.4 -3.1 -3.2 -2.8
Medication: Atenolol 0.6 0.8 2.5 0.9 0.6 1.1 0.7 1.1 1.3 0.5 0.9 0.8 0.8 0.8 0.8 0.7 0.9 -0.9 1.0 -1.6 0.8 0.9 1.0 0.9 0.6 0.8 0.9 1.0 0.7 0.8 0.8 0.8
Medication: Levothyroxine sodium 0.6 0.9 2.9 0.8 1.0 0.4 0.7 1.3 0.3 0.4 0.7 1.0 1.0 1.3 0.9 -0.2 0.9 -0.9 1.4 -0.9 0.8 1.0 1.7 0.8 1.1 0.9 1.0 1.3 0.8 0.8 1.0 1.2
Sitting height 0.2 1.7 3.5 -0.0 1.1 1.8 1.2 0.6 1.2 1.4 1.3 1.2 1.2 1.1 1.3 0.8 1.6 -1.5 1.6 -1.7 1.4 1.3 0.5 1.6 1.5 1.3 1.2 1.9 0.8 1.4 1.3 1.2
Chronic bronchitis/emphysema (father) 0.6 0.8 1.2 -1.1 -0.9 -0.6 -0.9 -0.7 -0.9 -0.3 -1.1 -1.0 -0.9 -1.1 -1.0 -0.7 -0.8 0.9 -0.5 1.1 -1.0 -1.0 -0.3 -0.9 -0.7 -0.9 -0.9 -0.7 -0.6 -1.0 -1.0 -0.8
High blood pressure (mother) 0.5 0.7 1.5 -1.0 -0.8 -0.8 -0.8 -0.9 -0.4 -1.2 -0.8 -0.8 -0.9 -0.6 -0.9 -0.8 -0.8 0.9 -0.5 -0.3 -0.9 -0.9 -1.2 -0.7 -1.0 -0.8 -0.9 -0.6 -0.6 -0.9 -0.9 -1.0
Body mass index (BMI) 0.4 1.6 3.7 -0.4 -1.4 -1.3 -1.2 -0.5 -1.5 -0.6 -1.5 -1.4 -1.4 -1.5 -1.4 -1.9 -1.1 1.1 -1.5 0.3 -1.4 -1.3 -1.1 -1.0 -0.9 -1.2 -1.4 -1.9 -0.5 -1.3 -1.5 -1.1
Impedance of leg (left) 0.4 1.8 22.3 -0.6 0.7 0.9 1.0 0.1 1.3 -1.4 1.1 0.9 0.9 1.4 0.9 0.6 0.8 -0.7 1.8 -4.7 1.0 0.9 -0.1 0.8 1.0 0.6 0.8 2.2 -0.8 0.9 1.0 0.8
Leg predicted mass (left) 0.0 0.2 2.7 0.6 0.0 0.1 0.1 0.3 0.1 1.6 -0.1 0.0 -0.0 -0.5 0.1 -0.2 0.4 -0.4 -0.4 0.3 0.1 0.1 0.0 0.5 0.3 0.3 0.1 -0.6 0.7 0.2 0.0 0.2
Trunk fat mass 0.2 0.7 3.7 -0.3 -1.0 -0.8 -0.4 -0.3 -0.7 -0.3 -0.7 -0.7 -0.8 -0.8 -0.7 -1.7 -0.5 0.4 -0.8 -1.9 -0.7 -0.7 -1.3 -0.3 -0.2 -0.6 -0.9 -0.9 -0.6 -0.6 -0.8 -0.6
Waist circumference 0.4 1.3 2.8 -0.8 -1.4 -1.1 -1.1 -0.5 -1.2 -0.8 -1.3 -1.3 -1.3 -1.4 -1.3 -1.7 -0.9 0.9 -1.2 -0.8 -1.2 -1.3 -1.3 -0.8 -0.8 -1.1 -1.3 -1.5 -0.8 -1.1 -1.4 -1.0
Number of incorrect matches in round 0.1 0.1 2.0 -0.1 -0.1 0.1 -0.2 0.4 0.1 0.3 -0.1 -0.1 -0.1 0.3 -0.0 -0.3 0.1 -0.2 0.4 -0.0 0.1 -0.1 1.4 0.1 0.4 0.0 0.2 -0.1 0.3 0.1 -0.1 0.5
Past tobacco smoking 0.1 0.2 1.9 -0.1 0.1 0.1 -0.1 -1.1 -0.7 0.5 -0.3 -0.1 -0.0 -0.3 -0.1 -0.8 -0.1 0.1 -1.0 1.4 -0.2 -0.1 0.4 -0.1 -0.2 -0.0 -0.0 -0.2 0.4 -0.1 -0.1 -0.1
Alcohol usually taken with meals 0.0 0.1 0.9 -0.2 0.0 -0.1 -0.2 -0.9 0.3 -0.3 0.1 -0.1 -0.1 0.1 -0.0 -0.4 -0.0 0.1 -0.1 0.2 -0.0 -0.1 -0.1 -0.1 0.1 -0.0 -0.2 0.3 -0.0 -0.0 -0.0 -0.2
Nervous feelings 0.4 0.8 2.3 0.4 0.9 0.8 0.6 0.3 0.9 1.5 0.9 0.7 0.7 0.6 0.9 0.8 0.9 -0.9 0.5 1.1 1.0 0.8 1.4 0.8 0.8 0.9 0.8 0.9 0.9 1.0 0.7 0.9
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.3 1.0 0.3 0.7 0.5 0.6 0.5 0.4 0.5 0.5 0.6 0.6 0.6 0.6 0.5 0.7 -0.7 1.0 0.8 0.5 0.5 0.3 0.7 0.5 0.7 0.5 0.6 0.7 0.6 0.5 0.3
Hearing difficulty/problems with background noise 0.4 0.6 2.9 -0.7 -1.0 -0.3 -0.9 -0.8 -1.0 -0.9 -0.6 -0.8 -0.8 -1.0 -0.8 -1.7 -0.5 0.5 -0.6 -1.4 -0.7 -0.7 -0.2 -0.5 -0.7 -0.6 -0.8 -0.3 -0.7 -0.7 -0.8 -0.7
Hair/balding pattern: Pattern 2 0.8 1.0 2.2 -0.9 -1.1 -0.1 -1.1 -1.3 -1.3 -0.9 -0.9 -1.0 -1.0 -1.2 -1.0 -1.5 -1.1 1.0 -0.7 1.0 -1.0 -1.0 -0.3 -1.1 -1.2 -1.0 -0.8 -1.0 -1.0 -1.0 -0.9 -1.0
Had menopause 1.3 1.6 3.4 1.9 1.3 1.1 1.3 1.3 1.4 1.2 1.2 1.3 1.3 1.4 1.2 0.5 1.2 -1.2 1.4 1.4 1.1 1.3 1.2 1.2 1.1 1.3 1.3 1.1 1.5 1.2 1.3 1.2
Had other major operations 0.4 0.5 5.9 0.4 0.2 0.8 0.7 0.2 0.3 -0.7 0.4 0.3 0.3 0.6 0.4 -0.5 0.6 -0.6 0.8 -2.4 0.5 0.4 0.2 0.7 0.9 0.4 0.6 0.6 0.3 0.5 0.4 0.7
Forced vital capacity (FVC) 1.1 4.4 5.9 1.7 2.3 1.9 2.4 1.3 1.6 2.0 2.3 2.3 2.2 2.2 2.4 1.1 2.3 -2.3 2.4 -0.5 2.4 2.3 1.3 2.4 2.1 2.3 2.2 2.4 2.2 2.4 2.3 2.1
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.2 1.0 0.3 0.4 0.6 0.2 1.0 -0.2 1.0 0.2 0.4 0.3 0.2 0.3 0.8 0.3 -0.3 0.1 -0.3 0.3 0.3 0.5 0.3 0.2 0.4 0.4 0.3 0.3 0.3 0.4 0.3
Ever unenthusiastic/disinterested for a whole week 0.8 0.9 1.6 -0.7 -1.0 -1.0 -1.0 -0.6 -1.0 -0.4 -1.0 -1.0 -1.0 -1.1 -1.1 -1.3 -1.1 1.1 -0.9 0.8 -1.1 -1.0 -0.5 -1.1 -0.9 -1.0 -0.9 -1.1 -0.5 -1.1 -1.0 -1.0
Qualifications: None of the above 1.5 3.3 8.9 2.4 1.7 1.9 1.9 3.0 2.0 1.0 1.8 1.9 1.8 2.1 1.8 1.2 1.8 -1.8 2.1 -1.8 1.7 1.8 1.1 1.8 1.9 1.8 1.7 1.4 1.1 1.8 1.7 1.9
Financial difficulties in last 2 years 0.7 0.9 3.0 -0.7 -1.0 -0.5 -0.8 -1.1 -1.2 -0.7 -1.0 -0.8 -0.8 -0.9 -0.9 -1.7 -1.0 1.0 -0.8 0.2 -1.0 -0.8 -0.8 -1.0 -1.1 -0.9 -0.9 -1.1 -0.8 -1.0 -0.8 -1.1
Mouth/teeth dental problems 7.9 12.1 15.7 -3.5 -3.6 -3.7 -4.0 -3.9 -3.2 -3.0 -3.6 -3.7 -3.7 -3.9 -3.7 -2.3 -3.6 3.6 -3.7 0.8 -3.6 -3.6 -2.6 -3.8 -3.2 -3.7 -3.7 -3.3 -3.6 -3.6 -3.6 -3.5
Heart attack 0.9 1.2 2.1 1.2 0.9 1.4 0.9 0.2 0.8 1.2 0.9 1.0 1.1 1.0 1.0 0.8 1.3 -1.2 0.8 -0.8 1.1 1.1 1.4 1.3 1.2 1.2 1.1 1.0 1.0 1.1 1.0 1.3
Allergy 0.0 0.1 0.9 -0.2 0.1 -0.2 -0.1 0.1 0.9 0.2 0.0 0.1 0.1 -0.0 0.1 1.0 -0.1 0.1 -0.2 -0.7 0.1 0.1 -0.1 -0.2 -0.2 -0.1 0.0 0.6 -0.4 -0.0 0.2 -0.1
Pain all over the body in last month 0.1 0.1 1.7 0.6 -0.1 0.1 0.3 -0.0 -0.5 0.9 0.0 0.0 0.0 0.2 -0.0 -1.3 0.1 -0.0 -0.1 0.2 -0.0 0.0 -0.2 0.2 0.0 -0.0 0.2 -0.4 -0.1 -0.0 0.0 0.1
Diabetes (self-reported) 0.2 0.4 0.6 -0.6 -0.7 -0.7 -0.7 -0.3 -0.7 -0.7 -0.5 -0.7 -0.6 -0.8 -0.6 0.6 -0.6 0.6 -0.8 0.4 -0.5 -0.7 0.0 -0.6 -0.6 -0.6 -0.6 -0.7 -0.7 -0.5 -0.7 -0.3
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 8.5 0.7 0.4 0.7 -0.1 -0.5 0.2 0.7 0.1 0.2 0.1 0.2 0.2 -0.2 0.2 -0.2 -0.0 2.9 0.3 0.2 1.3 0.1 0.2 0.3 0.4 -0.3 0.7 0.3 0.2 0.6
Medication: Ramipril 0.1 0.1 1.1 0.1 0.1 0.4 0.2 0.3 0.1 -0.2 -0.0 0.1 0.1 0.7 0.1 0.4 0.2 -0.0 0.5 -1.0 0.2 0.0 -1.0 0.3 -0.3 0.1 0.0 0.2 -0.7 0.2 0.1 -0.1
Medication: Simvastatin 0.7 1.0 3.7 1.1 1.1 0.6 1.1 1.4 0.7 0.7 1.1 1.0 1.0 0.9 1.0 1.9 0.9 -1.0 0.7 -0.6 1.0 0.9 0.7 1.0 1.1 1.0 1.0 0.9 1.2 1.0 0.9 1.0
Fluid intelligence score 0.1 0.2 1.1 -0.2 0.1 0.2 0.2 -1.1 -0.5 1.0 0.0 0.1 0.1 -0.1 0.1 0.2 0.1 -0.1 -0.7 -1.0 0.1 0.1 0.5 0.1 -0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.3
Illnesses of siblings 0.9 1.2 2.3 0.8 1.2 0.8 1.3 0.3 0.8 0.7 1.5 1.2 1.2 0.9 1.3 -0.1 1.1 -1.2 0.8 -0.4 1.4 1.2 0.8 1.2 1.2 1.2 1.2 1.2 1.4 1.3 1.3 1.1
Neuroticism score 1.1 2.3 7.1 -1.1 -1.5 -1.5 -1.6 -1.7 -1.5 -0.8 -1.4 -1.6 -1.6 -1.6 -1.6 -2.7 -1.4 1.4 -1.5 0.9 -1.5 -1.6 -1.0 -1.4 -1.5 -1.4 -1.5 -1.6 -1.1 -1.5 -1.6 -1.5
Weight 0.0 0.2 1.9 0.0 -0.5 -0.3 -0.2 0.0 -0.4 0.6 -0.5 -0.4 -0.4 -0.6 -0.4 -0.9 -0.1 0.0 -0.5 -1.4 -0.4 -0.3 -0.8 0.0 0.1 -0.2 -0.5 -0.7 0.0 -0.3 -0.5 -0.2
Impedance of arm (right) 0.0 0.2 1.6 0.1 0.2 0.1 0.5 -0.4 0.6 0.2 0.4 0.5 0.5 0.8 0.4 0.3 0.3 -0.3 0.5 -1.3 0.4 0.5 -0.1 0.3 0.6 0.3 0.4 0.5 -0.4 0.4 0.5 0.3
Arm fat percentage (right) 0.4 1.7 5.7 -0.4 -1.5 -1.6 -1.0 -0.7 -1.6 -0.9 -1.4 -1.3 -1.4 -1.3 -1.4 -2.4 -1.1 1.0 -1.4 -0.6 -1.4 -1.3 -1.5 -0.9 -0.7 -1.2 -1.4 -1.8 -0.8 -1.3 -1.4 -1.1
Trunk fat-free mass 0.2 1.3 3.3 1.0 1.1 1.1 1.1 1.0 1.2 1.8 1.0 1.0 1.0 0.7 1.1 0.8 1.4 -1.4 1.0 -0.8 1.1 1.1 0.9 1.4 1.2 1.2 1.1 0.9 1.4 1.2 1.0 1.2
Hip circumference 0.0 0.1 0.8 0.4 -0.1 0.1 0.1 0.1 -0.2 0.8 -0.2 -0.1 -0.1 -0.1 -0.1 -0.6 0.3 -0.3 -0.3 -0.9 -0.1 -0.0 -0.4 0.4 0.5 0.2 -0.1 -0.5 0.4 0.0 -0.1 0.2
Time employed in main current job 0.3 0.3 1.5 0.4 0.5 0.5 0.6 1.0 1.2 0.9 0.4 0.4 0.4 0.5 0.3 1.2 0.1 -0.2 0.7 0.3 0.3 0.4 0.1 0.1 0.5 0.2 0.4 0.6 0.6 0.2 0.4 0.2
Alcohol intake versus 10 years previously 0.4 0.6 0.9 -0.9 -0.7 -0.7 -0.8 0.7 -0.8 -0.9 -0.7 -0.7 -0.8 -0.7 -0.8 -0.0 -0.9 0.9 -0.2 -0.6 -0.8 -0.8 -0.7 -1.0 -0.8 -0.9 -0.8 -0.5 -0.9 -0.8 -0.7 -0.9
Father’s age at death 0.1 0.2 0.6 0.2 0.6 0.3 0.7 0.8 0.2 0.8 0.2 0.5 0.5 0.4 0.4 0.5 0.1 -0.1 0.6 0.3 0.3 0.4 -0.2 0.2 0.1 0.2 0.5 0.6 0.4 0.2 0.5 0.0
Worrier / anxious feelings 2.9 5.5 9.2 -2.0 -2.4 -2.6 -2.5 -2.7 -2.2 -1.5 -2.4 -2.5 -2.5 -2.2 -2.5 -3.0 -2.2 2.3 -2.6 1.5 -2.4 -2.5 -1.6 -2.3 -2.3 -2.3 -2.4 -2.5 -2.1 -2.4 -2.5 -2.2
Frequency of tiredness / lethargy in last 2 weeks 0.6 0.9 2.4 -0.9 -0.8 -0.6 -1.0 -0.9 -0.8 -0.0 -1.0 -0.9 -1.0 -1.2 -1.0 -1.4 -0.9 1.0 -0.6 1.5 -1.1 -1.0 -0.8 -1.0 -1.2 -0.9 -1.0 -0.7 -0.9 -1.0 -0.9 -1.1
Falls in the last year 0.5 0.7 1.9 0.8 0.8 1.0 0.9 1.4 0.8 0.7 0.8 0.8 0.8 1.1 0.7 0.3 0.6 -0.7 1.1 -0.3 0.7 0.8 0.6 0.7 1.0 0.7 0.8 0.7 0.7 0.7 0.7 1.1
Hair/balding pattern: Pattern 3 0.8 1.1 2.2 1.4 1.0 0.7 1.1 1.5 1.0 1.3 1.1 1.0 1.0 1.3 1.0 0.3 1.1 -1.1 0.5 -0.1 1.0 1.1 1.0 1.1 1.2 1.1 1.0 0.7 1.4 1.0 1.0 1.2
Number of live births 0.8 1.2 2.2 0.9 1.3 1.1 1.3 0.7 1.2 -0.5 1.1 1.2 1.3 1.2 1.1 0.8 1.1 -0.9 1.2 0.2 0.9 1.2 1.2 1.0 0.9 1.2 1.2 1.5 1.5 1.0 1.2 1.1
Forced expiratory volume in 1-second (FEV1) 0.8 2.6 3.9 1.6 1.8 1.5 1.8 1.0 0.9 1.5 1.7 1.7 1.7 1.7 1.8 0.9 1.9 -1.9 1.5 0.2 1.9 1.7 0.8 2.0 1.7 1.8 1.7 1.6 1.8 1.9 1.7 1.6
Pulse rate 0.2 0.4 5.0 0.1 0.4 0.2 0.4 0.1 -0.2 1.2 0.2 0.3 0.3 0.1 0.4 0.0 0.5 -0.5 0.0 2.2 0.6 0.4 0.9 0.5 0.5 0.5 0.5 0.1 0.9 0.5 0.4 0.7
Happiness 0.2 0.2 1.5 -0.1 -0.3 -0.9 -0.3 -0.9 0.0 0.3 -0.2 -0.3 -0.3 -0.5 -0.2 -0.9 -0.4 0.4 -0.1 1.2 -0.2 -0.3 0.6 -0.5 -0.5 -0.3 -0.1 -0.4 0.1 -0.3 -0.2 -0.3
Noisy workplace 0.6 0.7 2.8 -0.6 -1.0 -0.8 -0.7 -0.0 -0.6 -0.6 -0.9 -0.9 -0.8 -0.8 -0.9 0.1 -0.8 0.8 -0.9 -0.5 -0.9 -0.9 -1.7 -0.8 -0.8 -0.8 -1.1 -0.9 -1.0 -0.9 -0.9 -1.1
Qualifications: A levels/AS levels or equivalent 5.4 11.9 20.4 -3.8 -3.5 -3.6 -3.2 -4.5 -2.9 -2.8 -3.6 -3.6 -3.5 -3.3 -3.6 -2.2 -3.4 3.5 -3.6 -0.4 -3.6 -3.6 -4.5 -3.2 -3.9 -3.5 -3.7 -3.2 -3.2 -3.5 -3.5 -3.8
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 3.8 -0.2 0.5 0.2 0.4 -0.6 0.4 -0.6 0.5 0.5 0.4 0.8 0.5 0.4 0.4 -0.4 1.0 -1.9 0.5 0.5 -0.1 0.4 0.4 0.4 0.4 1.0 0.2 0.5 0.5 0.4
Mouth/teeth dental problems: Dentures 7.1 12.0 14.3 3.4 3.6 3.7 3.7 3.8 3.6 2.7 3.6 3.7 3.7 3.7 3.6 2.6 3.6 -3.5 3.5 0.2 3.5 3.6 3.2 3.6 3.1 3.7 3.7 3.5 3.7 3.5 3.6 3.4
Asthma 0.2 0.3 2.6 -0.9 -0.7 -0.2 -0.5 0.1 -0.3 -0.7 -0.5 -0.5 -0.5 -0.6 -0.6 -0.3 -0.5 0.5 0.3 -1.6 -0.6 -0.6 0.1 -0.5 -0.2 -0.6 -0.4 -0.2 -0.7 -0.6 -0.5 -0.4
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 1.7 0.3 0.6 0.6 0.4 1.3 0.3 0.5 0.7 0.6 0.6 0.7 0.7 0.9 1.1 -0.9 1.0 -0.1 0.9 0.6 1.0 1.0 0.6 0.9 0.7 0.8 0.7 0.9 0.6 0.8
Medication: Cholesterol lowering 0.1 0.2 3.2 -0.3 0.2 0.1 0.2 -0.2 0.0 -0.1 0.3 0.1 0.2 0.1 0.2 1.3 0.1 -0.2 0.0 -1.8 0.2 0.1 -0.6 0.2 0.3 0.1 -0.1 0.5 -0.0 0.2 0.0 0.1
Depression (self-reported) 0.4 0.5 1.5 0.1 0.6 1.2 0.6 0.3 0.4 0.3 0.4 0.6 0.6 0.9 0.6 -0.1 0.8 -0.7 0.5 0.4 0.6 0.6 1.2 0.8 0.6 0.8 0.7 0.5 1.2 0.7 0.6 0.7
Medication: Lansoprazole 0.4 0.4 2.2 0.3 0.5 1.3 0.2 0.3 0.2 -0.3 0.4 0.5 0.5 0.6 0.6 -0.6 0.8 -0.7 0.6 -0.5 0.6 0.5 1.5 0.6 0.6 0.7 0.7 0.8 0.5 0.6 0.5 0.8
Prospective memory result 0.1 0.1 1.1 -0.1 0.1 0.1 -0.1 0.4 0.5 0.8 -0.1 0.0 0.1 -0.2 -0.1 1.1 -0.4 0.3 0.2 1.0 -0.2 -0.0 0.4 -0.5 -0.1 -0.2 -0.1 0.1 -0.3 -0.2 -0.0 -0.1
Lung cancer (father) 3.1 3.7 6.7 -2.6 -1.9 -2.0 -1.9 -2.4 -1.2 -1.2 -2.1 -2.0 -2.0 -2.2 -2.1 -1.0 -2.0 2.1 -1.4 1.8 -2.1 -2.1 -1.6 -2.0 -2.1 -2.0 -2.0 -1.3 -1.4 -2.0 -2.0 -2.2
Illnesses of mother 0.7 0.8 1.9 0.6 0.8 0.8 0.8 0.7 0.8 1.4 1.0 0.9 0.9 0.6 1.0 0.7 1.0 -0.9 0.7 -1.2 1.0 0.9 0.8 0.9 0.9 0.9 0.9 1.2 0.3 1.0 1.0 0.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 3.0 4.4 1.9 1.9 1.6 1.9 1.2 1.4 1.3 1.8 1.8 1.8 1.8 2.0 1.0 2.0 -2.0 1.7 0.4 2.0 1.8 1.1 2.1 1.7 2.0 1.8 1.5 2.1 2.0 1.8 1.7
Pulse wave Arterial Stiffness index 0.1 0.1 1.5 -0.0 -0.1 0.3 0.2 1.2 -0.0 0.7 0.0 0.1 0.1 0.1 0.1 -0.4 0.2 -0.1 0.4 -0.8 0.1 -0.0 0.2 0.2 0.0 0.1 0.1 0.0 -0.2 0.1 -0.0 0.0
Impedance of arm (left) 0.0 0.2 3.0 -0.1 -0.1 -0.1 0.3 -0.7 0.2 -0.0 0.3 0.2 0.2 0.5 0.3 0.1 0.1 -0.2 0.2 -1.7 0.3 0.2 -0.4 0.1 0.4 0.1 0.1 0.3 -0.7 0.2 0.3 0.1
Arm fat mass (right) 0.3 1.3 3.8 -0.4 -1.3 -1.3 -1.0 -0.6 -1.3 -0.4 -1.3 -1.2 -1.3 -1.3 -1.3 -2.0 -0.9 0.9 -1.4 -0.4 -1.3 -1.2 -1.4 -0.8 -0.6 -1.0 -1.3 -1.7 -0.5 -1.2 -1.3 -1.0
Trunk predicted mass 0.2 1.3 3.6 1.1 1.1 1.2 1.1 1.1 1.2 1.9 1.1 1.1 1.0 0.7 1.1 0.9 1.4 -1.4 1.0 -0.7 1.1 1.1 0.9 1.4 1.3 1.2 1.1 0.9 1.4 1.2 1.0 1.2
Standing height 0.4 3.6 13.0 0.8 1.5 1.9 1.9 1.0 2.2 2.3 1.9 1.8 1.8 1.7 1.9 1.7 2.0 -2.0 2.1 -3.6 1.9 1.9 0.5 2.0 2.0 1.8 1.7 2.3 0.9 1.9 1.9 1.6
Length of working week for main job 0.1 0.2 1.9 -0.4 -0.1 0.2 -0.0 0.5 0.0 -1.4 -0.2 0.0 -0.0 -0.0 -0.0 -0.3 0.0 0.0 0.4 -1.1 -0.1 -0.0 -0.5 0.0 -0.2 -0.0 -0.1 0.2 -0.4 -0.1 0.0 -0.2
Exposure to tobacco smoke at home 0.3 0.3 0.8 0.9 0.4 0.6 0.6 0.5 0.5 0.7 0.5 0.5 0.5 0.3 0.6 -0.2 0.6 -0.7 0.5 -0.9 0.6 0.6 0.4 0.7 0.7 0.5 0.6 0.7 0.4 0.6 0.6 0.6
Breastfed as a baby 2.2 2.7 8.2 1.5 1.7 1.6 1.5 1.1 1.8 2.2 1.4 1.5 1.4 1.0 1.5 1.3 1.7 -1.7 1.4 2.2 1.5 1.4 2.0 1.7 1.7 1.8 1.5 1.4 2.9 1.6 1.3 1.6
Tense / ‘highly strung’ 0.1 0.1 0.7 0.5 0.1 0.1 -0.0 -0.5 0.8 0.0 0.2 0.0 -0.0 0.2 0.1 -0.6 0.2 -0.3 0.2 -0.8 0.2 0.1 -0.1 0.2 0.2 0.1 0.0 -0.2 -0.1 0.2 -0.0 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.6 2.3 -0.4 -0.8 -0.4 -0.7 -0.5 -1.3 0.1 -0.8 -0.8 -0.9 -0.9 -0.7 -1.5 -0.6 0.5 -0.9 1.2 -0.7 -0.8 -0.4 -0.5 -0.4 -0.6 -0.7 -0.9 0.1 -0.7 -0.8 -0.8
Hair/balding pattern: Pattern 4 0.2 0.5 1.7 -0.7 -0.4 -0.7 -0.5 -0.1 -0.3 -0.5 -0.8 -0.5 -0.5 -0.9 -0.6 0.5 -0.6 0.7 -0.6 -1.3 -0.7 -0.6 -1.1 -0.6 -0.8 -0.6 -0.7 -0.1 -0.9 -0.7 -0.6 -0.8
Birth weight of first child 0.3 0.5 1.5 -0.5 -0.6 -0.7 -0.7 -0.8 -0.4 -0.8 -0.7 -0.7 -0.6 -0.6 -0.6 -1.0 -0.3 0.5 -0.2 -1.2 -0.6 -0.7 -1.0 -0.3 -0.8 -0.5 -0.7 -0.5 -0.9 -0.5 -0.7 -0.7
Peak expiratory flow (PEF) 1.0 2.3 3.4 1.3 1.5 1.6 1.6 1.1 1.4 1.0 1.5 1.5 1.5 1.2 1.6 1.8 1.8 -1.7 1.3 -1.0 1.7 1.5 1.3 1.8 1.6 1.7 1.6 1.5 1.6 1.7 1.5 1.7
Pulse wave reflection index 0.5 0.7 2.1 0.9 0.6 0.7 0.7 1.5 1.0 0.2 0.7 0.7 0.7 0.8 0.7 0.8 0.7 -0.7 1.2 -1.3 0.7 0.6 1.2 0.7 0.6 0.7 0.8 0.5 0.4 0.7 0.7 0.9
Ever highly irritable/argumentative for 2 days 0.4 0.4 1.8 -0.4 -0.6 -0.8 -0.5 -0.7 -1.3 -0.9 -0.4 -0.5 -0.6 -0.5 -0.6 -1.2 -0.6 0.6 -0.3 -0.8 -0.7 -0.5 -0.6 -0.5 -0.3 -0.6 -0.6 -0.5 -0.3 -0.6 -0.6 -0.5
Loud music exposure frequency 5.7 6.2 8.3 -2.9 -2.7 -2.4 -2.4 -2.1 -2.7 -1.8 -2.7 -2.6 -2.6 -2.5 -2.8 -2.1 -2.8 2.7 -2.4 -0.5 -2.8 -2.6 -1.6 -2.7 -2.7 -2.8 -2.5 -2.1 -2.2 -2.8 -2.7 -2.4
Qualifications: O levels/GCSEs or equivalent 4.5 7.2 10.9 -2.4 -2.6 -2.9 -2.5 -3.3 -2.6 -1.8 -2.7 -2.7 -2.7 -2.8 -2.8 -1.3 -2.6 2.8 -3.2 2.1 -2.7 -2.7 -3.3 -2.5 -3.0 -2.6 -2.7 -2.8 -2.2 -2.7 -2.6 -3.0
Mouth/teeth dental problems: Bleeding gums 0.2 0.2 1.1 0.2 -0.3 -0.0 -0.3 -0.9 -0.9 0.1 -0.4 -0.3 -0.4 -0.2 -0.3 -1.1 -0.1 0.1 -0.9 -0.1 -0.2 -0.3 -0.6 0.0 0.0 -0.2 -0.3 -0.8 -0.1 -0.2 -0.3 -0.0
Blood clot in the leg (DVT) 2.4 3.1 4.8 1.9 1.9 1.9 2.1 1.5 2.2 1.3 1.8 1.9 1.9 1.5 1.8 1.3 1.8 -1.9 1.7 -0.5 1.7 2.0 1.2 1.9 1.9 1.8 1.9 1.7 1.9 1.7 1.9 2.0
Medication: Paracetamol 1.2 1.9 4.5 1.1 1.3 1.7 1.4 1.6 0.9 0.1 1.4 1.3 1.3 1.5 1.4 0.2 1.7 -1.5 2.1 -1.9 1.4 1.3 0.7 1.7 1.0 1.4 1.3 1.8 0.9 1.5 1.3 1.4
Headache pain in last month 0.5 0.8 1.3 -1.1 -1.1 -0.1 -1.1 0.2 -0.9 -0.6 -1.0 -1.1 -1.1 -0.7 -1.0 -1.1 -0.7 0.7 -0.4 -0.8 -1.0 -1.1 -0.8 -0.7 -0.8 -0.9 -1.1 -0.7 -0.8 -0.9 -1.2 -1.0
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 1.8 0.5 0.4 0.3 0.2 0.6 0.7 1.1 0.1 0.4 0.4 0.3 0.3 0.4 0.2 -0.1 0.4 1.3 0.2 0.4 0.7 0.1 0.2 0.3 0.4 0.1 0.4 0.2 0.4 0.4
Glaucoma (self-reported) 1.8 2.2 4.2 1.2 1.3 1.9 1.6 1.9 1.4 0.6 1.4 1.4 1.4 1.8 1.5 2.1 1.6 -1.6 1.7 -1.2 1.5 1.4 0.4 1.6 1.6 1.5 1.3 1.2 0.8 1.6 1.4 1.3
Gout (self-reported) 0.2 0.2 1.1 0.3 0.4 0.7 0.5 0.3 0.1 -0.7 0.5 0.4 0.4 0.5 0.4 0.4 0.4 -0.5 0.6 -1.0 0.4 0.4 0.3 0.5 0.7 0.4 0.4 0.4 0.5 0.4 0.4 0.5
Hypothyroidism/myxoedema (self-reported) 0.2 0.5 1.9 0.2 0.7 0.3 0.4 1.2 0.1 -0.3 0.6 0.6 0.5 0.8 0.6 0.0 0.6 -0.6 1.2 -1.4 0.5 0.6 0.9 0.5 0.8 0.5 0.6 1.1 0.4 0.6 0.6 0.8
Medication: Amlodipine 0.2 0.3 1.4 0.9 0.4 0.9 0.1 -0.2 0.2 0.9 0.5 0.4 0.4 0.2 0.4 0.8 0.6 -0.6 0.4 -0.3 0.5 0.5 1.2 0.5 0.6 0.5 0.5 0.4 0.5 0.5 0.4 0.6
Medication: Ventolin 100micrograms inhaler 0.8 1.0 6.1 -1.1 -0.9 -0.5 -0.9 -1.1 -0.7 -2.5 -0.9 -0.8 -0.8 -0.6 -0.9 -1.7 -1.0 1.0 -0.3 -1.7 -1.0 -0.8 -0.2 -1.1 -0.8 -1.0 -0.7 -0.5 -0.9 -1.0 -0.8 -0.7
Birth weight 1.6 3.4 4.9 1.7 2.0 1.8 2.2 2.2 2.0 1.9 1.9 1.9 2.0 2.0 1.9 1.2 1.8 -1.8 2.0 -0.9 1.8 2.0 0.8 1.8 1.7 1.8 1.9 2.1 1.8 1.8 2.0 1.7
Chronic bronchitis/emphysema (mother) 0.3 0.3 0.9 0.7 0.4 0.7 0.6 0.6 0.3 0.8 0.6 0.5 0.5 0.5 0.6 -0.6 0.7 -0.7 0.5 0.1 0.6 0.5 -0.2 0.7 0.7 0.7 0.3 0.4 1.0 0.7 0.4 0.2
High blood pressure (siblings) 0.5 0.7 1.4 -0.9 -0.8 -0.5 -0.9 -0.2 -0.3 -0.6 -1.2 -0.9 -0.9 -0.5 -1.0 -0.4 -0.8 0.9 -0.4 0.4 -1.0 -0.9 -0.9 -0.9 -0.9 -0.9 -0.9 -0.7 -1.2 -1.0 -0.9 -0.8
Forced vital capacity (FVC), Best measure 1.2 4.2 5.9 1.8 2.2 1.8 2.2 1.5 1.8 1.5 2.2 2.2 2.1 2.1 2.3 1.2 2.4 -2.3 2.3 0.0 2.4 2.1 1.4 2.4 2.0 2.3 2.2 2.2 2.4 2.4 2.1 2.0
Body fat percentage 0.4 1.4 5.1 -0.7 -1.4 -1.2 -0.9 -0.6 -1.3 -1.0 -1.2 -1.2 -1.2 -1.1 -1.2 -2.3 -0.9 0.8 -1.1 -2.0 -1.2 -1.1 -1.6 -0.8 -0.6 -1.1 -1.3 -1.3 -1.0 -1.1 -1.3 -1.0
Leg fat percentage (right) 0.7 2.6 6.2 -1.4 -1.8 -1.5 -1.3 -0.8 -1.6 -1.9 -1.6 -1.6 -1.7 -1.4 -1.6 -2.5 -1.4 1.3 -1.2 -2.5 -1.6 -1.6 -2.0 -1.2 -1.0 -1.6 -1.7 -1.4 -1.5 -1.5 -1.7 -1.4
Arm fat-free mass (right) 0.2 1.0 2.3 1.0 0.9 1.1 0.9 1.1 0.9 1.5 0.8 0.9 0.8 0.5 0.9 0.4 1.2 -1.2 0.8 -1.2 0.9 0.9 0.7 1.3 1.1 1.1 0.9 0.7 1.2 1.0 0.8 1.1
Exposure to tobacco smoke outside home 2.3 3.1 5.2 -2.1 -2.1 -1.7 -1.8 -1.2 -1.6 -2.1 -1.9 -1.8 -1.8 -1.8 -1.8 -0.6 -1.7 1.6 -1.3 -1.8 -1.8 -1.7 -1.8 -1.7 -1.6 -1.8 -1.9 -1.5 -2.3 -1.8 -1.8 -1.7
Comparative body size at age 10 0.1 0.3 1.5 0.5 -0.2 -0.5 -0.1 -0.6 -0.4 0.4 -0.1 -0.2 -0.2 -0.2 -0.3 1.0 -0.4 0.4 -0.8 1.1 -0.3 -0.2 -1.2 -0.4 -0.5 -0.2 -0.5 -1.0 -0.1 -0.3 -0.3 -0.6
Number of full brothers 0.1 0.1 1.0 0.1 0.1 0.1 0.1 1.0 -0.2 -0.2 0.1 0.2 0.2 0.0 0.1 -0.6 -0.0 0.1 0.4 0.1 0.1 0.2 0.4 -0.1 0.3 0.1 0.1 0.3 0.1 0.0 0.2 -0.1
Worry too long after embarrassment 0.1 0.2 2.4 0.3 0.0 0.4 -0.0 -0.6 -0.2 1.5 -0.0 -0.1 -0.1 -0.3 -0.1 -0.5 -0.2 0.2 -0.6 1.1 -0.2 -0.0 -0.7 -0.2 0.1 -0.2 -0.2 -0.1 -0.0 -0.2 -0.0 -0.2
Seen a psychiatrist for nerves, anxiety, tension or depression 1.7 2.2 5.2 2.0 1.4 1.7 1.3 1.3 0.9 1.2 1.5 1.4 1.3 1.3 1.6 -0.2 1.7 -1.7 1.0 0.5 1.7 1.4 2.3 1.7 1.2 1.7 1.7 1.0 2.1 1.7 1.4 1.5
Wheeze or whistling in the chest in last year 0.1 0.2 2.3 0.2 0.2 0.4 0.1 -0.3 0.6 -0.9 0.1 0.2 0.2 0.1 0.1 -0.3 0.1 -0.2 0.3 -0.3 0.1 0.2 1.5 0.1 0.4 0.2 0.4 0.2 0.7 0.1 0.2 0.5
Number of children fathered 2.0 2.2 5.6 1.6 1.4 1.4 1.2 1.5 1.5 2.4 1.5 1.4 1.3 1.3 1.5 0.6 1.6 -1.6 1.2 1.1 1.5 1.4 2.2 1.5 1.7 1.5 1.5 1.0 1.5 1.6 1.3 1.8
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.4 1.8 -1.2 -0.4 -0.2 -0.6 -1.1 -0.3 -1.4 -0.4 -0.6 -0.5 -0.5 -0.6 -0.1 -0.5 0.5 -0.3 0.9 -0.5 -0.5 -0.7 -0.6 -0.3 -0.6 -0.7 -0.3 -0.5 -0.5 -0.6 -0.6
Age at first live birth 1.2 2.1 8.2 -1.9 -1.4 -1.5 -1.6 -2.9 -1.1 -1.0 -1.2 -1.5 -1.5 -1.4 -1.4 -1.6 -1.4 1.4 -1.5 0.4 -1.3 -1.5 -0.9 -1.4 -1.5 -1.4 -1.4 -0.9 -1.2 -1.3 -1.4 -1.6
Pulse wave peak to peak time 0.1 0.1 1.1 0.2 0.3 -0.0 0.0 -1.0 0.2 -0.4 0.2 0.1 0.1 0.1 0.1 0.5 0.0 -0.1 -0.1 0.6 0.1 0.2 -0.0 0.0 0.2 0.1 0.2 0.2 0.3 0.1 0.2 0.2
Health satisfaction 0.5 0.6 2.2 -0.6 -0.9 -1.0 -0.7 -0.6 -0.8 -0.9 -0.7 -0.8 -0.8 -0.7 -0.8 -1.4 -0.7 0.7 -0.8 -1.5 -0.8 -0.8 -0.6 -0.6 -0.5 -0.8 -0.7 -0.6 -0.7 -0.8 -0.8 -0.7
Shortness of breath walking on level ground 0.1 0.2 0.7 0.2 0.3 0.1 0.1 0.6 0.6 0.4 0.2 0.3 0.3 0.3 0.3 0.3 0.4 -0.3 0.4 -0.3 0.3 0.3 0.9 0.3 0.4 0.4 0.4 0.3 0.7 0.3 0.3 0.4
Qualifications: College or University degree 1.2 3.7 9.0 -3.0 -1.8 -2.4 -1.9 -3.0 -1.5 -1.1 -1.9 -2.0 -2.0 -1.8 -2.0 -1.0 -1.9 2.0 -1.9 0.1 -2.0 -2.0 -1.9 -1.9 -2.0 -2.0 -2.0 -1.3 -1.5 -2.0 -2.0 -2.1
Eye problems/disorders: None of the above 0.3 0.4 2.2 0.3 0.8 0.1 0.4 0.5 0.2 1.3 0.6 0.7 0.7 0.4 0.6 0.8 0.1 -0.1 0.5 1.5 0.5 0.6 0.7 0.0 -0.2 0.4 0.6 0.8 0.3 0.4 0.7 0.2
Mouth/teeth dental problems: Loose teeth 0.3 0.3 5.0 0.5 0.2 0.2 0.6 1.0 0.1 -0.4 0.2 0.4 0.4 0.5 0.3 0.6 0.3 -0.2 0.3 -2.2 0.2 0.3 -0.2 0.4 0.4 0.2 0.3 0.3 -0.2 0.2 0.3 0.4
Emphysema/chronic bronchitis 0.2 0.3 1.1 0.2 -0.5 -0.2 -0.4 -0.3 -0.5 -1.1 -0.3 -0.5 -0.5 -0.4 -0.5 -0.6 -0.4 0.4 -0.8 0.6 -0.4 -0.5 0.3 -0.4 -0.4 -0.4 -0.3 -1.0 -0.1 -0.4 -0.5 -0.3
Medication for pain relief, constipation, heartburn 1.0 1.8 4.5 -1.1 -1.1 -1.6 -1.3 -1.6 -1.1 -0.1 -1.1 -1.2 -1.2 -1.3 -1.2 -0.6 -1.7 1.5 -2.0 2.1 -1.2 -1.2 -0.3 -1.7 -1.5 -1.4 -1.1 -1.5 -1.0 -1.4 -1.2 -1.3
Neck or shoulder pain in last month 0.6 0.8 2.4 -0.8 -1.1 0.0 -1.1 -1.2 -0.8 -1.5 -1.0 -1.0 -1.0 -1.1 -0.8 -1.3 -0.3 0.4 -0.8 -1.0 -0.6 -0.9 -0.9 -0.3 -0.6 -0.6 -1.0 -0.8 -0.9 -0.5 -1.0 -0.7
Medication: Blood pressure 0.2 0.4 1.7 0.7 0.5 0.8 0.6 0.2 0.4 -0.1 0.8 0.6 0.6 0.6 0.7 -0.1 0.8 -0.8 0.7 -1.3 0.7 0.6 0.4 0.8 0.5 0.7 0.6 0.7 0.2 0.7 0.6 0.6
Angina (self-reported) 0.1 0.1 0.4 0.2 -0.3 0.1 -0.3 -0.5 -0.1 -0.0 -0.3 -0.2 -0.2 -0.3 -0.3 0.2 -0.2 0.2 -0.4 -0.4 -0.3 -0.2 0.5 -0.2 -0.4 -0.2 -0.1 -0.6 -0.4 -0.2 -0.3 -0.0
Migraine (self-reported) 0.6 0.7 2.4 0.3 0.6 1.4 0.7 1.0 0.7 1.2 0.7 0.6 0.6 0.7 0.7 0.3 1.1 -1.0 0.9 -1.5 0.8 0.6 0.2 1.2 0.9 0.9 0.6 1.0 0.9 0.9 0.6 0.8
Medication: Ibuprofen 0.1 0.1 0.5 -0.3 -0.2 -0.4 -0.4 0.6 -0.4 -0.0 -0.1 -0.2 -0.2 -0.2 -0.1 0.1 0.3 -0.1 0.2 0.3 0.1 -0.2 0.7 0.2 0.0 0.1 -0.1 -0.0 0.1 0.1 -0.2 0.2
Medication: Allopurinol 1.0 1.3 2.1 1.0 1.3 1.2 1.3 0.4 0.8 0.3 1.2 1.2 1.2 1.2 1.2 1.0 1.2 -1.3 1.1 -0.8 1.1 1.3 0.9 1.2 1.5 1.2 1.2 1.3 1.4 1.1 1.2 1.3
Medication: Omeprazole 1.6 1.9 5.2 1.0 1.4 1.1 1.7 2.3 1.4 0.8 1.1 1.5 1.4 1.7 1.4 -0.6 1.4 -1.3 1.9 -0.5 1.2 1.4 0.7 1.4 1.6 1.4 1.4 1.7 1.6 1.3 1.4 1.2
Medication: Seretide 50 evohaler 0.2 0.2 0.4 -0.6 -0.6 -0.1 -0.3 0.6 -0.2 -0.1 -0.6 -0.5 -0.4 -0.4 -0.5 0.0 -0.6 0.6 0.1 0.1 -0.6 -0.5 0.2 -0.5 -0.5 -0.5 -0.3 -0.4 -0.2 -0.6 -0.5 -0.6
Mean time to correctly identify matches 0.3 0.5 0.9 0.7 0.7 0.8 0.6 1.0 0.8 -0.4 0.8 0.7 0.7 0.9 0.7 0.3 0.9 -0.8 0.8 -0.4 0.8 0.6 0.2 0.8 0.6 0.8 0.5 0.6 0.5 0.8 0.6 0.5
Heart disease (mother) 0.8 1.0 2.4 -0.4 -1.0 -0.7 -0.8 -0.7 -0.9 -0.7 -1.1 -1.1 -1.0 -0.9 -1.1 -1.5 -1.1 1.1 -0.6 0.8 -1.1 -1.0 -1.6 -1.0 -0.8 -1.1 -1.1 -1.4 -0.7 -1.1 -1.1 -1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.3 1.5 -0.2 -0.5 -0.3 -0.4 -0.3 -0.5 -1.2 -0.4 -0.5 -0.5 -0.4 -0.5 1.1 -0.4 0.5 -0.7 -0.1 -0.6 -0.5 -0.4 -0.4 -0.4 -0.4 -0.6 -0.9 -0.4 -0.5 -0.6 -0.5
Whole body fat mass 0.2 0.7 3.2 -0.2 -1.0 -0.9 -0.6 -0.4 -0.9 -0.3 -0.9 -0.9 -0.9 -0.9 -0.9 -1.8 -0.5 0.5 -0.9 -1.6 -0.8 -0.8 -1.1 -0.4 -0.3 -0.7 -0.9 -1.1 -0.5 -0.7 -1.0 -0.6
Leg fat mass (right) 0.4 1.5 4.2 -0.8 -1.5 -1.2 -1.1 -0.7 -1.3 -0.8 -1.3 -1.3 -1.4 -1.3 -1.3 -2.0 -1.0 0.9 -1.2 -1.8 -1.3 -1.2 -1.5 -0.9 -0.7 -1.2 -1.4 -1.4 -1.0 -1.2 -1.4 -1.0
Arm predicted mass (right) 0.2 1.0 2.8 1.1 0.9 1.1 0.9 1.1 0.9 1.7 0.9 0.8 0.8 0.4 0.9 0.4 1.2 -1.2 0.7 -0.9 0.9 0.9 0.6 1.3 1.0 1.1 0.9 0.6 1.2 1.0 0.8 1.0
Pulse rate, automated reading 0.1 0.4 3.1 -0.8 -0.5 -0.5 -0.6 -0.5 -0.6 -0.1 -0.8 -0.6 -0.6 -0.8 -0.5 0.1 -0.5 0.5 -0.4 1.8 -0.4 -0.5 0.1 -0.5 -0.2 -0.5 -0.5 -0.6 0.0 -0.4 -0.5 -0.3
Alcohol intake frequency. 0.0 0.1 2.2 0.5 -0.0 0.2 0.0 0.3 -0.0 -0.1 -0.1 0.1 0.1 0.1 0.0 -1.5 -0.1 0.1 -0.1 0.3 -0.0 0.0 0.2 -0.1 -0.4 0.0 0.1 -0.2 -0.3 -0.1 0.1 -0.0
Comparative height size at age 10 0.1 0.5 8.3 -0.0 0.3 0.5 0.5 0.3 0.9 1.1 0.3 0.5 0.5 0.4 0.5 0.3 0.4 -0.5 0.6 -2.9 0.5 0.5 -0.4 0.4 0.7 0.3 0.4 0.8 -0.4 0.4 0.5 0.2
Number of full sisters 0.2 0.2 1.1 0.2 0.2 0.7 0.3 0.7 1.1 0.1 0.6 0.3 0.3 0.3 0.4 0.7 0.5 -0.5 0.4 -0.5 0.5 0.3 0.6 0.5 0.5 0.5 0.3 0.4 0.3 0.5 0.3 0.4
Suffer from ‘nerves’ 0.6 0.9 3.3 0.6 1.0 1.4 0.8 1.1 0.5 1.8 1.1 0.9 0.8 0.7 1.0 0.3 1.1 -1.1 0.6 -0.2 1.0 0.9 0.7 1.1 0.9 1.0 0.8 1.1 0.9 1.0 0.8 0.9
Overall health rating 0.3 0.6 5.2 0.2 -0.9 -0.2 -0.7 -0.1 -1.1 -0.9 -0.9 -0.7 -0.7 -0.6 -0.8 -2.3 -0.6 0.6 -0.2 -0.4 -0.8 -0.6 0.1 -0.6 -0.7 -0.6 -0.5 -1.0 -0.8 -0.7 -0.7 -0.4
Chest pain or discomfort 1.7 2.4 4.1 -1.9 -1.6 -1.5 -1.5 -1.7 -0.5 -0.9 -1.7 -1.6 -1.6 -1.6 -1.7 0.6 -1.8 1.8 -1.4 -0.2 -1.8 -1.7 -1.3 -1.8 -2.0 -1.8 -1.6 -1.2 -1.4 -1.8 -1.6 -1.8
Had major operations 0.7 0.8 1.3 -1.0 -0.9 -0.5 -1.0 -0.4 -0.5 -0.7 -0.9 -1.0 -1.0 -0.9 -1.0 -1.1 -0.9 0.9 -0.9 -0.4 -1.1 -1.0 -1.0 -0.8 -0.9 -1.0 -1.0 -0.8 -0.7 -1.0 -1.1 -0.8
Age at last live birth 1.2 1.8 5.1 -1.8 -1.4 -1.0 -1.6 -2.2 -1.3 -2.3 -1.2 -1.5 -1.4 -1.3 -1.3 -1.1 -1.2 1.2 -1.3 0.7 -1.2 -1.4 -0.4 -1.3 -1.2 -1.2 -1.3 -1.0 -0.9 -1.2 -1.3 -1.2
Family relationship satisfaction 0.9 1.1 3.6 1.0 1.0 0.9 1.1 0.1 1.2 1.1 1.0 1.1 1.1 0.8 1.0 0.4 0.9 -1.0 1.1 0.1 1.0 1.1 1.9 0.9 1.1 1.0 1.3 1.1 1.7 1.0 1.1 1.3
Leg pain on walking 0.1 0.2 0.9 0.2 0.1 -0.1 0.2 0.6 -0.2 -0.6 0.2 0.1 0.1 0.4 0.2 -1.0 0.3 -0.4 0.4 -1.0 0.3 0.2 0.5 0.3 0.5 0.3 0.2 0.2 0.6 0.3 0.1 0.3
Qualifications: NVQ or HND or HNC or equivalent 0.0 0.1 0.3 -0.2 -0.0 -0.1 0.1 0.5 -0.5 -0.1 -0.2 -0.0 0.0 -0.1 -0.1 -0.5 -0.2 0.2 0.4 0.3 -0.2 0.0 0.2 -0.1 -0.2 -0.1 0.1 0.2 0.2 -0.2 0.0 -0.0
Commuting to job workplace: Car/motor vehicle 0.3 0.3 1.4 -0.2 -0.6 -0.4 -0.3 -0.9 -1.2 0.5 -0.6 -0.5 -0.5 -0.6 -0.5 -0.5 -0.4 0.4 -0.2 0.1 -0.5 -0.4 -1.1 -0.3 -0.2 -0.5 -0.6 -0.4 -0.2 -0.5 -0.5 -0.6
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 1.2 -0.6 -0.6 -1.1 -0.8 -0.1 -0.3 -0.7 -0.6 -0.7 -0.7 -0.9 -0.6 0.1 -0.4 0.4 -0.8 0.6 -0.5 -0.7 0.0 -0.4 -0.3 -0.5 -0.6 -0.5 -0.3 -0.5 -0.7 -0.3
Medication: Aspirin 0.1 0.2 2.1 0.1 0.1 0.1 0.2 0.2 0.1 -1.2 0.2 0.2 0.2 0.3 0.2 -0.2 0.5 -0.4 0.6 -1.4 0.1 0.2 -0.4 0.5 0.4 0.3 0.0 0.3 0.1 0.2 0.2 0.3
Supplements: Vitamin C 0.1 0.1 0.5 0.3 0.2 0.4 0.3 0.2 0.0 -0.3 0.3 0.2 0.3 0.3 0.3 0.4 0.5 -0.4 0.7 -0.3 0.3 0.3 0.3 0.6 0.3 0.4 0.3 0.3 0.4 0.4 0.3 0.3
Knee pain experienced in last month 0.1 0.2 1.8 0.5 -0.3 -0.5 -0.2 -1.4 -0.5 -0.4 -0.2 -0.2 -0.3 -0.1 -0.2 -0.1 -0.1 0.1 -0.4 -0.4 -0.2 -0.2 -0.2 -0.1 0.1 -0.1 -0.2 -0.7 -0.3 -0.1 -0.2 -0.2
Hypertension (Self-reported) 0.1 0.3 0.7 0.6 0.5 0.5 0.4 0.5 0.7 0.2 0.4 0.4 0.5 0.6 0.5 0.7 0.6 -0.6 0.9 -0.6 0.5 0.5 0.8 0.6 0.3 0.5 0.5 0.4 0.4 0.5 0.4 0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 1.0 0.6 0.5 0.7 0.5 0.5 0.8 -0.2 0.3 0.5 0.5 0.5 0.6 0.3 0.8 -0.7 0.6 -0.4 0.6 0.5 0.4 0.8 1.0 0.7 0.5 0.7 0.7 0.6 0.5 0.6
Illnesses of father: Heart disease 2.2 3.1 5.5 -1.5 -1.9 -1.4 -2.0 -1.3 -1.7 -1.2 -2.0 -2.0 -2.1 -1.8 -1.9 -1.6 -1.4 1.6 -1.9 1.3 -1.8 -2.1 -1.3 -1.5 -1.5 -1.7 -1.9 -2.4 -1.7 -1.7 -2.1 -1.6
Illnesses of siblings: Diabetes 1.9 2.3 3.4 -1.5 -1.5 -1.2 -1.5 -0.9 -1.1 -1.8 -1.5 -1.6 -1.6 -1.6 -1.6 -0.5 -1.6 1.6 -1.4 1.1 -1.5 -1.7 -1.8 -1.6 -1.8 -1.6 -1.7 -1.5 -1.8 -1.6 -1.6 -1.8
Smoking status: Previous 0.3 0.5 1.7 -0.7 -0.6 -1.1 -0.4 0.5 0.1 -1.0 -0.4 -0.6 -0.6 -0.4 -0.6 1.0 -0.6 0.6 0.3 -1.2 -0.6 -0.6 -1.3 -0.5 -0.5 -0.7 -0.7 -0.3 -1.0 -0.6 -0.6 -0.7
Forced expiratory volume in 1-second (FEV1), predicted 1.7 3.6 11.2 1.6 1.7 2.1 2.0 1.0 2.2 2.7 1.7 1.9 1.8 1.6 1.9 3.3 2.0 -2.0 1.3 -1.4 1.9 1.9 0.7 2.1 1.9 1.9 1.8 1.7 1.4 2.0 1.9 1.8
Whole body fat-free mass 0.2 0.9 3.4 1.1 0.9 0.9 0.9 0.9 0.9 1.9 0.8 0.8 0.8 0.4 0.9 0.5 1.2 -1.2 0.6 -0.5 0.9 0.9 0.8 1.2 1.0 1.1 0.9 0.5 1.3 1.0 0.8 1.0
Leg fat-free mass (right) 0.1 0.4 3.9 1.1 0.4 0.5 0.5 0.5 0.4 2.0 0.3 0.4 0.4 -0.1 0.5 0.1 0.7 -0.7 -0.1 0.3 0.5 0.5 0.5 0.8 0.6 0.7 0.5 -0.3 1.0 0.5 0.4 0.6
Arm fat percentage (left) 0.5 2.1 6.5 -0.5 -1.7 -1.7 -1.2 -0.9 -1.8 -1.0 -1.5 -1.5 -1.6 -1.5 -1.5 -2.5 -1.2 1.1 -1.7 -0.7 -1.5 -1.5 -1.7 -1.1 -0.8 -1.3 -1.6 -2.0 -0.9 -1.4 -1.6 -1.3
Average weekly red wine intake 0.1 0.2 2.0 0.3 0.1 0.5 0.1 -0.4 0.4 0.3 0.3 0.2 0.2 0.3 0.3 1.4 0.4 -0.4 0.1 -1.2 0.3 0.2 -0.1 0.4 0.3 0.3 0.2 0.0 -0.2 0.4 0.2 0.2
Handedness (chirality/laterality): Left-handed 1.3 1.6 2.4 0.9 1.2 1.6 1.4 1.4 1.2 0.2 1.4 1.3 1.3 1.4 1.3 0.5 1.5 -1.5 1.6 -0.4 1.3 1.3 0.6 1.5 1.3 1.4 1.3 1.5 1.1 1.4 1.3 1.2
Mood swings 0.8 1.4 5.1 -0.5 -1.1 -1.5 -1.1 -0.5 -1.2 -0.7 -1.2 -1.1 -1.2 -0.8 -1.2 -2.3 -1.4 1.3 -0.8 0.2 -1.4 -1.1 -1.0 -1.4 -1.3 -1.3 -1.1 -1.3 -1.3 -1.4 -1.1 -1.2
Loneliness, isolation 0.2 0.3 3.3 0.5 0.6 0.0 0.4 -0.3 -0.3 -0.1 0.5 0.5 0.5 0.3 0.5 -0.8 0.5 -0.5 0.3 1.8 0.6 0.4 0.6 0.5 0.1 0.6 0.5 0.5 0.9 0.5 0.4 0.3
Long-standing illness, disability or infirmity 1.1 1.7 3.2 -0.9 -1.4 -1.1 -1.2 -1.1 -1.8 -1.0 -1.7 -1.3 -1.3 -1.2 -1.5 -1.7 -1.5 1.4 -0.9 -0.6 -1.6 -1.2 -0.5 -1.5 -1.1 -1.5 -1.2 -1.5 -1.3 -1.6 -1.3 -0.9
Ever had bowel cancer screening 0.5 0.5 1.3 -0.5 -0.7 -0.8 -0.8 -0.5 -1.1 -0.9 -0.5 -0.7 -0.7 -0.8 -0.7 -1.0 -0.5 0.5 -0.5 -1.2 -0.7 -0.7 -0.8 -0.5 -0.7 -0.6 -0.9 -0.2 -0.9 -0.6 -0.8 -0.8
Diabetes diagnosed by doctor 0.2 0.4 0.9 -0.8 -0.8 -0.7 -0.8 -0.5 -0.9 -0.8 -0.5 -0.7 -0.7 -0.7 -0.6 0.3 -0.5 0.5 -0.8 0.3 -0.6 -0.7 -0.2 -0.5 -0.5 -0.5 -0.7 -0.7 -0.6 -0.5 -0.7 -0.4
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.5 0.1 0.1 -0.2 0.2 0.5 0.3 0.1 0.1 0.1 0.1 -0.0 0.1 0.4 0.1 -0.1 0.1 0.7 0.1 0.1 0.1 0.1 0.2 0.1 0.1 -0.3 0.4 0.1 0.1 0.1
Friendships satisfaction 0.3 0.3 2.2 -0.9 -0.3 -0.5 -0.4 -1.2 -0.4 0.4 -0.3 -0.4 -0.4 -0.7 -0.4 -0.1 -0.6 0.6 -0.3 1.5 -0.4 -0.4 0.5 -0.7 -0.5 -0.5 -0.2 -0.1 0.0 -0.5 -0.4 -0.3
Qualifications: nursing, teaching 1.2 1.8 2.5 -1.0 -1.4 -1.4 -1.5 -1.4 -1.4 -0.8 -1.6 -1.5 -1.4 -1.5 -1.5 -0.6 -1.3 1.3 -1.3 0.8 -1.5 -1.4 -1.1 -1.4 -1.5 -1.4 -1.5 -1.5 -1.4 -1.4 -1.4 -1.3
Commuting to job workplace: Walk 2.9 3.1 5.7 1.4 1.9 1.5 1.8 1.2 1.5 1.6 1.9 1.9 1.9 1.7 1.9 0.3 1.8 -1.8 1.8 0.3 1.9 1.8 2.4 1.8 1.8 1.9 2.0 2.0 1.9 1.9 1.9 2.0
Eye problems/disorders: Cataract 0.3 0.3 1.4 0.4 0.4 0.4 0.2 0.3 1.2 0.3 0.6 0.4 0.3 0.7 0.5 0.2 0.7 -0.6 0.5 -0.7 0.6 0.4 0.4 0.6 0.9 0.5 0.3 0.5 0.5 0.6 0.4 0.6
Mouth/teeth dental problems: Mouth ulcers 6.2 9.9 12.9 2.8 3.1 3.2 3.6 3.6 2.7 3.3 3.1 3.3 3.2 3.5 3.3 3.3 3.2 -3.2 3.6 -0.9 3.2 3.2 2.1 3.4 3.2 3.2 3.2 3.2 3.0 3.2 3.2 3.1
Medication for cholesterol 0.6 0.9 1.8 0.7 1.0 0.8 1.1 0.3 1.0 1.0 1.2 1.0 0.9 0.8 1.1 0.4 1.0 -1.0 0.5 -0.9 1.1 0.9 -0.3 1.1 1.0 1.0 0.8 1.4 0.7 1.1 1.0 0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.4 0.2 0.0 0.6 0.4 0.4 -0.0 0.2 0.3 0.2 0.1 0.1 0.1 -0.3 0.4 -0.2 0.3 -0.3 0.1 0.1 -0.5 0.5 0.2 0.3 0.1 0.3 0.4 0.2 0.1 -0.1
Back pain experienced in last month 1.2 1.7 3.1 -0.8 -1.5 -1.6 -1.7 -1.3 -1.3 -0.4 -1.6 -1.5 -1.5 -1.6 -1.3 -1.7 -1.2 1.1 -1.2 0.8 -1.1 -1.4 -0.4 -1.3 -1.2 -1.3 -1.4 -1.8 -1.2 -1.1 -1.5 -1.1
Mineral and other dietary supplements 1.7 2.2 3.4 -1.0 -1.6 -1.8 -1.3 -1.6 -1.6 -1.2 -1.7 -1.5 -1.5 -1.5 -1.6 -0.8 -1.5 1.4 -1.7 -1.5 -1.7 -1.4 -1.5 -1.4 -1.1 -1.6 -1.5 -1.9 -1.7 -1.6 -1.5 -1.2
Breast cancer (self-reported) 1.8 2.2 3.9 0.7 1.5 1.8 1.6 1.3 1.9 1.3 1.3 1.5 1.5 1.3 1.4 1.4 1.3 -1.3 1.5 -0.3 1.3 1.5 2.0 1.3 1.9 1.3 1.6 1.8 1.7 1.3 1.5 1.7
Asthma (self-reported) 0.1 0.2 2.9 -0.6 -0.5 0.1 -0.3 0.1 -0.1 -0.6 -0.3 -0.3 -0.4 -0.4 -0.4 -0.1 -0.3 0.3 0.4 -1.7 -0.4 -0.4 0.2 -0.3 -0.1 -0.4 -0.3 -0.1 -0.6 -0.3 -0.4 -0.2
Osteoporosis (self-reported) 2.1 2.6 4.5 -1.2 -1.6 -1.2 -1.5 -1.8 -1.3 -1.6 -1.6 -1.5 -1.6 -1.7 -1.5 -2.1 -1.9 1.8 -1.5 1.8 -1.5 -1.5 -1.2 -1.9 -1.8 -1.7 -1.5 -1.7 -1.4 -1.6 -1.5 -1.6
Osteoarthritis (self-reported) 0.5 0.6 2.1 -0.1 -0.9 -0.5 -0.8 -1.0 -1.5 -0.5 -0.9 -0.8 -0.8 -0.8 -0.8 -1.2 -0.5 0.6 -0.4 0.9 -0.7 -0.8 -0.2 -0.6 -0.9 -0.6 -0.7 -1.4 -0.6 -0.7 -0.8 -0.7
Medication: Aspirin 0.1 0.1 1.5 -0.3 -0.1 -0.1 -0.1 0.2 0.2 -1.2 -0.1 -0.1 -0.1 -0.0 -0.1 0.1 0.1 -0.1 0.4 -1.1 -0.1 -0.0 -0.5 0.2 0.2 0.0 -0.2 0.1 -0.1 -0.0 -0.1 0.0
Medication: Gliclazide 0.2 0.3 1.2 -0.3 0.6 0.6 0.3 -0.1 0.5 -0.5 0.6 0.5 0.5 0.3 0.6 0.5 0.4 -0.5 0.6 -0.5 0.6 0.6 0.7 0.3 0.4 0.4 0.5 1.1 0.1 0.5 0.6 0.5
Illnesses of father: None of the above (group 1) 2.2 2.7 3.9 1.7 1.8 1.1 1.9 1.6 1.7 1.1 2.0 1.8 1.9 1.8 1.8 1.7 1.4 -1.5 1.9 -1.3 1.7 1.8 0.9 1.4 1.5 1.6 1.7 1.9 1.2 1.6 1.9 1.5
Smoking status: Current 0.6 0.9 3.2 1.5 0.8 1.3 0.8 1.0 1.0 0.4 0.7 0.9 0.9 0.7 0.9 -0.4 0.7 -0.9 0.9 1.1 0.9 1.0 1.8 0.7 0.9 0.9 1.1 0.2 1.2 0.8 0.9 1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 3.1 6.6 8.7 2.8 2.9 2.3 2.7 2.5 1.6 1.7 2.5 2.7 2.7 2.6 2.8 2.0 2.9 -2.8 2.7 2.1 2.9 2.7 1.4 2.9 2.4 2.9 2.6 2.4 2.9 2.9 2.7 2.5
Whole body water mass 0.1 0.8 3.5 1.0 0.8 0.9 0.8 1.0 0.8 1.9 0.7 0.8 0.7 0.4 0.8 0.5 1.1 -1.1 0.6 -0.3 0.8 0.8 0.7 1.2 1.0 1.0 0.9 0.4 1.2 0.9 0.7 0.9
Leg predicted mass (right) 0.1 0.5 4.3 1.2 0.5 0.6 0.6 0.7 0.6 2.1 0.4 0.6 0.5 0.0 0.6 0.2 0.8 -0.9 0.0 0.3 0.6 0.6 0.5 0.9 0.7 0.8 0.6 -0.2 1.1 0.7 0.5 0.7
Arm fat mass (left) 0.3 1.1 3.6 -0.2 -1.3 -1.3 -0.9 -0.5 -1.2 -0.3 -1.2 -1.1 -1.2 -1.3 -1.2 -1.9 -0.8 0.7 -1.2 -0.6 -1.1 -1.1 -1.3 -0.7 -0.5 -0.9 -1.2 -1.6 -0.5 -1.0 -1.2 -0.9
Number of self-reported non-cancer illnesses 0.1 0.2 2.2 -0.3 -0.4 0.2 -0.4 0.4 -0.2 -1.5 -0.1 -0.3 -0.4 0.1 -0.2 -0.5 0.1 -0.1 0.3 -0.9 -0.1 -0.4 -0.3 0.1 -0.1 -0.1 -0.4 -0.3 -0.5 -0.0 -0.4 -0.1
Average weekly champagne plus white wine intake 0.1 0.1 1.2 0.2 -0.1 -0.1 -0.2 -1.1 0.7 0.7 0.0 -0.1 -0.1 -0.2 -0.1 0.1 -0.1 0.0 -0.2 0.1 -0.1 -0.0 0.5 -0.1 0.2 -0.0 0.0 -0.0 0.3 -0.1 -0.0 0.1
Miserableness 0.1 0.2 2.7 0.4 0.3 0.1 0.2 -0.3 -0.5 -0.1 0.2 0.2 0.1 0.3 0.2 -1.6 0.3 -0.3 0.1 0.2 0.2 0.2 0.5 0.3 0.3 0.3 0.3 -0.0 0.4 0.3 0.1 0.4
Guilty feelings 0.1 0.1 1.2 0.0 -0.3 -0.4 -0.2 0.1 -1.1 -0.1 -0.2 -0.3 -0.3 -0.4 -0.3 -0.4 -0.2 0.3 -0.1 0.4 -0.3 -0.3 -0.4 -0.2 -0.7 -0.3 -0.2 -0.2 -0.3 -0.3 -0.2 -0.5
Wears glasses or contact lenses 0.1 0.2 2.5 -0.1 -0.4 -0.2 -0.6 -0.2 -0.1 -1.6 -0.3 -0.4 -0.4 -0.1 -0.2 -0.3 -0.1 0.1 -0.4 0.1 -0.1 -0.4 0.5 -0.2 -0.2 -0.1 -0.3 -0.5 -0.1 -0.1 -0.4 -0.2
Ever taken oral contraceptive pill 1.1 1.2 2.2 -0.6 -1.0 -1.1 -1.2 -0.6 -0.7 -0.4 -0.9 -1.1 -1.0 -1.2 -1.1 -0.4 -1.3 1.3 -1.0 1.3 -1.1 -1.1 -1.0 -1.4 -1.3 -1.2 -1.1 -1.5 -1.1 -1.2 -1.1 -1.4
Hearing aid user 0.2 0.3 0.9 0.4 0.7 0.3 0.4 -0.3 0.5 0.4 0.7 0.6 0.5 0.5 0.6 0.7 0.4 -0.4 0.6 1.0 0.5 0.5 0.3 0.4 0.5 0.5 0.4 0.4 0.1 0.5 0.5 0.5
Mother’s age at death 3.9 4.9 7.9 2.1 2.3 2.4 2.3 2.8 1.8 1.6 2.4 2.3 2.3 2.5 2.4 2.1 2.3 -2.4 2.0 -0.5 2.4 2.3 1.9 2.3 2.1 2.3 2.3 2.1 2.1 2.4 2.3 2.4
Financial situation satisfaction 0.2 0.2 2.0 -0.5 -0.5 -0.3 -0.4 -0.3 -0.4 -0.3 -0.5 -0.4 -0.4 -0.5 -0.5 -1.4 -0.5 0.6 -0.4 -0.1 -0.5 -0.4 0.2 -0.5 -0.4 -0.4 -0.4 -0.5 -0.2 -0.5 -0.4 -0.4
Tinnitus: Yes, now most or all of the time 1.5 1.8 3.2 1.8 1.4 1.1 1.4 0.9 1.1 1.4 1.4 1.4 1.4 1.1 1.4 0.8 1.6 -1.6 1.0 0.8 1.5 1.4 0.7 1.6 1.6 1.6 1.3 0.9 1.5 1.5 1.4 1.1
Commuting to job workplace: Public transport 0.5 0.5 2.3 -1.5 -0.7 -0.5 -0.7 -0.7 0.2 -0.6 -0.9 -0.8 -0.8 -1.0 -0.7 0.4 -0.8 0.8 -0.9 -0.0 -0.7 -0.9 0.1 -0.8 -0.8 -0.8 -0.6 -0.2 -0.6 -0.7 -0.8 -0.7
Eye problems/disorders: Glaucoma 0.7 0.8 1.9 0.9 0.7 1.2 1.0 1.4 0.5 0.4 0.7 0.8 0.8 1.0 0.8 1.0 1.1 -1.0 0.9 -0.8 0.8 0.8 -0.1 1.2 1.3 0.9 0.7 0.5 0.6 0.9 0.7 0.8
Medication: Blood pressure 0.1 0.2 0.7 0.6 0.3 0.4 0.3 0.8 0.3 0.0 0.1 0.2 0.2 0.5 0.2 0.2 0.5 -0.4 0.8 -0.2 0.2 0.3 0.4 0.5 0.3 0.4 0.3 0.1 0.6 0.2 0.2 0.4
Pain type(s) experienced in last month: Hip pain 1.0 1.2 2.5 -1.3 -1.1 -0.9 -1.5 -0.9 -1.1 -1.6 -1.4 -1.2 -1.2 -1.3 -1.2 -0.0 -1.2 1.1 -0.5 0.5 -1.2 -1.2 -0.0 -1.3 -1.1 -1.2 -1.1 -0.9 -0.9 -1.2 -1.2 -0.9
Supplements: Fish oil (including cod liver oil) 1.8 2.3 4.1 1.1 1.6 1.9 1.6 0.7 1.8 1.0 2.0 1.7 1.7 1.5 1.7 0.7 1.6 -1.5 1.4 -0.1 1.8 1.6 1.4 1.5 1.4 1.6 1.6 2.0 1.4 1.7 1.7 1.3
High cholesterol (Self-reported) 0.7 1.3 4.5 1.4 1.3 1.1 1.3 1.4 0.8 0.8 1.2 1.1 1.2 1.0 1.1 2.1 1.0 -1.1 1.3 -1.1 1.0 1.2 -0.2 1.1 1.2 1.0 0.9 1.2 0.8 1.0 1.1 1.0
Medication: Bendroflumethiazide 0.2 0.4 1.4 0.8 0.5 0.2 0.6 1.2 0.2 0.1 0.6 0.4 0.5 0.8 0.5 0.1 0.6 -0.6 0.9 -0.6 0.5 0.5 0.6 0.7 0.6 0.5 0.6 0.6 0.7 0.6 0.5 0.7
Medication: Paracetamol 0.6 0.9 4.7 0.8 0.8 1.0 0.8 1.0 0.7 -0.2 0.9 0.8 0.8 1.0 0.9 0.2 1.1 -0.9 1.5 -2.2 0.8 0.8 1.0 1.1 0.6 0.9 1.0 1.2 0.3 0.9 0.8 1.1
Medication: Lisinopril 0.3 0.4 1.5 0.7 0.7 0.5 0.6 0.2 0.6 0.4 0.6 0.6 0.6 0.8 0.6 -0.6 0.6 -0.6 0.5 1.2 0.6 0.7 0.3 0.6 0.7 0.7 0.6 0.5 0.9 0.6 0.7 0.5
Medication: Atorvastatin 1.0 1.3 2.4 0.7 1.0 1.4 1.1 0.7 1.5 0.8 1.1 1.1 1.1 1.1 1.1 1.4 1.2 -1.2 1.5 -0.9 1.1 1.1 0.8 1.2 0.9 1.1 1.1 1.3 0.8 1.1 1.1 1.3
Illnesses of father: High blood pressure 1.3 1.6 3.8 -1.5 -1.4 -0.6 -1.4 -2.0 -1.0 -1.3 -1.4 -1.4 -1.4 -1.4 -1.4 -0.5 -1.0 1.1 -1.6 -0.0 -1.3 -1.3 -1.3 -1.0 -1.0 -1.2 -1.4 -1.4 -1.4 -1.2 -1.4 -1.2
Alcohol drinker status: Never 0.1 0.1 0.5 0.5 0.1 0.7 0.2 -0.2 -0.2 0.2 0.3 0.2 0.2 0.2 0.3 0.2 0.3 -0.3 0.0 0.4 0.3 0.2 0.5 0.3 0.3 0.3 0.3 -0.0 0.2 0.3 0.2 0.4
Ever smoked 0.3 0.6 4.0 0.2 0.4 0.7 0.6 1.3 1.0 0.1 0.8 0.6 0.5 0.7 0.6 0.9 0.5 -0.6 1.6 -2.0 0.7 0.6 -0.1 0.5 0.6 0.5 0.5 0.9 -0.1 0.6 0.6 0.5
Basal metabolic rate 0.1 0.4 2.4 0.7 0.4 0.5 0.5 0.7 0.5 1.6 0.4 0.5 0.4 0.1 0.5 0.1 0.8 -0.8 0.3 -0.7 0.5 0.5 0.3 0.9 0.8 0.7 0.5 0.1 0.9 0.6 0.4 0.6
Leg fat percentage (left) 0.3 1.1 7.2 -0.6 -1.1 -0.8 -0.6 -0.2 -1.0 -1.4 -0.9 -0.9 -0.9 -0.7 -1.0 -1.9 -0.7 0.7 -0.6 -2.7 -1.0 -0.9 -1.3 -0.6 -0.4 -0.9 -1.0 -0.8 -0.9 -0.9 -1.0 -0.7
Arm fat-free mass (left) 0.4 1.8 3.7 1.3 1.3 1.4 1.3 1.7 1.3 1.9 1.1 1.3 1.2 0.9 1.3 0.9 1.6 -1.5 1.2 -0.8 1.2 1.3 1.0 1.6 1.5 1.4 1.3 1.1 1.6 1.3 1.2 1.4
Number of operations (self-reported) 1.0 1.4 3.2 -1.8 -1.4 -0.7 -1.1 -0.3 -1.4 -1.3 -1.2 -1.3 -1.3 -1.3 -1.3 -1.5 -1.3 1.3 -0.7 -0.7 -1.3 -1.3 -0.7 -1.2 -1.0 -1.4 -1.2 -0.8 -1.0 -1.3 -1.4 -1.1
Average weekly beer plus cider intake 0.3 0.4 3.6 0.7 0.7 0.4 0.8 1.9 -0.1 1.0 0.4 0.7 0.7 0.5 0.5 0.9 0.2 -0.2 1.0 -0.1 0.4 0.6 -0.6 0.2 0.0 0.3 0.5 0.5 -0.1 0.3 0.7 0.4
Irritability 2.5 4.2 7.7 -2.3 -2.2 -2.2 -2.0 -2.8 -1.6 -1.6 -1.8 -2.2 -2.2 -2.2 -2.1 -2.2 -2.0 2.0 -2.3 -1.2 -2.0 -2.2 -1.5 -1.9 -2.1 -2.1 -2.0 -1.9 -1.9 -2.0 -2.2 -1.9
Risk taking 0.1 0.1 1.0 -0.9 -0.3 -0.5 0.1 -0.0 0.0 -0.4 -0.2 -0.2 -0.2 -0.0 -0.2 -0.2 0.1 -0.0 0.3 -1.0 -0.1 -0.2 -0.4 0.1 -0.3 -0.1 -0.1 0.2 0.2 -0.1 -0.2 -0.3
Ever had prostate specific antigen (PSA) test 0.3 0.4 1.2 0.2 0.6 0.1 0.4 0.3 0.4 0.2 0.8 0.6 0.6 0.8 0.7 -0.2 0.7 -0.6 0.7 0.1 0.7 0.6 1.1 0.5 0.8 0.7 0.6 1.0 0.6 0.7 0.6 0.6
Fractured/broken bones in last 5 years 0.2 0.3 1.4 -0.1 -0.4 -0.5 -0.3 -0.9 -0.7 -0.1 -0.7 -0.4 -0.4 -0.3 -0.5 0.1 -0.5 0.4 -0.7 -0.3 -0.5 -0.4 -1.2 -0.4 -0.5 -0.5 -0.5 -0.7 -1.0 -0.5 -0.5 -0.5
Age started oral contraceptive pill 1.8 2.3 6.7 1.5 1.5 1.5 1.2 0.6 1.3 1.1 1.6 1.4 1.5 1.3 1.5 0.5 1.7 -1.7 1.0 0.6 1.6 1.5 2.6 1.5 1.8 1.7 1.6 1.5 1.8 1.6 1.4 2.0
Diastolic blood pressure, automated reading 0.0 0.1 1.1 0.0 -0.0 -0.1 -0.1 0.7 0.7 -0.7 -0.3 -0.2 -0.1 0.1 -0.2 1.1 0.0 -0.1 0.3 -0.7 -0.2 -0.1 0.0 0.1 0.6 -0.1 -0.2 -0.2 0.2 -0.1 -0.2 0.2
Ever depressed for a whole week 0.1 0.1 2.3 -0.3 -0.1 -0.2 -0.2 -0.3 -0.5 -0.4 -0.1 -0.2 -0.3 -0.3 -0.2 -1.5 0.1 -0.1 0.2 0.5 -0.1 -0.2 0.5 0.1 0.3 -0.0 -0.1 0.0 0.7 -0.0 -0.2 0.1
Unable to work because of sickness or disability 0.3 0.4 2.8 -0.2 -0.6 -0.1 -0.4 -0.3 -0.5 -1.1 -0.5 -0.5 -0.5 -0.4 -0.5 -1.7 -0.7 0.6 -0.5 -0.5 -0.5 -0.4 -0.6 -0.7 -0.5 -0.6 -0.5 -0.5 -0.9 -0.6 -0.4 -0.6
Commuting to job workplace: Cycle 0.2 0.3 2.1 -0.6 -0.1 -0.7 -0.4 -1.4 -0.1 -1.2 -0.2 -0.3 -0.3 -0.3 -0.3 -0.9 -0.3 0.4 -0.8 -0.4 -0.4 -0.3 -0.3 -0.4 -0.6 -0.3 -0.3 -0.2 -0.4 -0.4 -0.3 -0.4
Myopia 0.4 0.5 1.5 -0.8 -0.9 -0.4 -0.7 -0.5 -0.7 0.5 -0.7 -0.7 -0.7 -0.6 -0.6 -1.2 -0.5 0.5 -0.7 -0.4 -0.5 -0.7 -1.1 -0.4 -0.9 -0.5 -0.8 -0.4 -0.7 -0.5 -0.7 -1.1
Vascular/heart problems diagnosed by doctor 0.0 0.1 0.4 -0.5 0.0 -0.0 0.0 0.3 -0.3 -0.0 -0.0 0.0 -0.0 -0.2 -0.0 -0.1 -0.2 0.2 -0.3 0.6 -0.1 -0.0 -0.5 -0.2 0.0 -0.1 -0.1 0.2 -0.1 -0.1 0.0 -0.2
Cholesterol lowering medication 0.7 1.1 4.6 1.3 1.0 0.7 1.1 2.1 0.8 0.5 0.8 1.0 1.0 1.0 0.9 1.0 1.0 -1.0 1.3 0.1 0.8 1.0 1.3 1.1 0.9 1.1 1.1 0.7 1.2 0.9 1.0 1.2
Medication: Omeprazole (e.g. Zanprol) 0.8 0.9 2.6 0.7 1.0 1.0 1.2 1.6 0.6 0.5 0.6 1.0 1.0 1.2 0.9 -1.1 0.9 -0.8 1.4 -0.2 0.8 1.0 0.2 1.0 1.3 0.9 0.9 1.2 1.1 0.8 1.0 0.7
Pain experienced in last month 0.3 0.5 2.1 0.4 0.8 0.5 1.0 0.6 0.6 0.1 0.8 0.8 0.8 0.8 0.8 1.5 0.4 -0.4 0.4 0.2 0.7 0.7 0.2 0.5 0.4 0.6 0.8 0.8 0.6 0.6 0.9 0.5
Supplements: Calcium 0.9 0.9 6.5 0.4 0.9 1.1 0.7 0.8 1.1 1.7 0.6 0.8 0.7 0.4 0.8 0.8 0.5 -0.6 1.2 2.6 0.8 0.7 0.8 0.5 0.7 0.7 0.7 1.1 1.6 0.7 0.7 0.6
Basal cell carcinoma (self-reported) 5.7 6.8 13.3 -2.5 -2.8 -2.3 -2.7 -1.9 -3.6 -2.3 -2.8 -2.8 -2.8 -2.9 -2.8 -2.0 -2.7 2.7 -2.6 0.8 -2.9 -2.8 -1.9 -2.7 -2.6 -2.7 -2.7 -2.7 -2.2 -2.8 -2.8 -2.6
Heart attack/myocardial infarction (self-reported) 0.9 1.2 1.8 1.2 1.0 1.4 1.0 0.2 0.8 1.2 0.9 1.0 1.1 1.0 1.1 0.9 1.3 -1.3 0.8 -0.9 1.1 1.1 1.3 1.3 1.2 1.2 1.1 1.0 1.1 1.1 1.1 1.3
Deep venous thrombosis (DVT) (self-reported) 1.4 1.8 2.8 1.6 1.4 1.3 1.6 1.0 1.7 0.8 1.3 1.4 1.4 1.0 1.4 0.7 1.3 -1.5 1.2 -0.3 1.2 1.5 1.1 1.4 1.5 1.4 1.5 1.1 1.5 1.3 1.4 1.7
Heart disease (siblings) 0.3 0.4 3.5 1.0 0.3 0.4 0.4 1.9 0.6 0.2 -0.0 0.3 0.4 0.6 0.1 1.0 0.4 -0.3 0.8 -0.3 -0.0 0.4 0.9 0.4 0.7 0.3 0.4 -0.1 0.7 0.1 0.3 0.8
Alcohol drinker status: Previous 0.1 0.1 0.3 -0.3 -0.2 -0.3 -0.1 0.1 0.1 0.5 -0.3 -0.2 -0.2 -0.3 -0.3 -0.1 -0.4 0.4 -0.4 0.3 -0.5 -0.2 -0.3 -0.4 -0.5 -0.3 -0.2 -0.1 -0.4 -0.4 -0.2 -0.3
Pack years of smoking 0.7 1.0 2.1 -1.0 -1.0 -1.2 -1.2 -1.1 -0.9 -0.5 -0.9 -1.0 -1.0 -1.5 -1.0 -0.0 -1.0 1.0 -1.3 1.4 -0.9 -1.0 -0.6 -1.0 -0.9 -1.0 -1.1 -1.2 -0.7 -0.9 -1.1 -1.0
Impedance of whole body 0.1 0.7 10.1 -0.5 0.2 0.4 0.6 -0.3 0.7 -0.9 0.6 0.5 0.5 1.0 0.6 0.2 0.4 -0.4 0.9 -3.2 0.6 0.5 -0.4 0.4 0.7 0.3 0.4 1.2 -0.8 0.6 0.6 0.4
Leg fat mass (left) 0.2 0.8 3.7 -0.4 -1.0 -0.8 -0.6 -0.3 -0.9 -0.6 -0.9 -0.9 -0.9 -0.9 -0.9 -1.8 -0.7 0.6 -0.8 -1.9 -0.9 -0.8 -1.2 -0.5 -0.3 -0.8 -0.9 -1.0 -0.6 -0.8 -0.9 -0.7
Arm predicted mass (left) 0.2 1.0 2.3 0.9 0.9 1.0 0.9 1.4 0.9 1.5 0.8 0.8 0.8 0.5 0.8 0.5 1.2 -1.2 0.9 -1.0 0.8 0.9 0.8 1.3 1.1 1.0 0.9 0.7 1.3 0.9 0.8 1.1