Best TWAS P=2.29e-08 · Best GWAS P=1.84e-07 conditioned to 0.824
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ARHGEF26 | 0.10 | 0.06 | enet | 8 | 0.07 | 2.2e-06 | -4.8 | 5.3 | 1.1e-07 | -0.95 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Pancreas | ARHGEF26 | 0.26 | 0.26 | lasso | 5 | 0.28 | 3.2e-12 | -5.1 | 5.6 | 2.3e-08 | -0.95 | 0.01 | 0.99 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | ARHGEF26 | 0.13 | 0.11 | lasso | 4 | 0.07 | 6.8e-05 | -5.1 | 5.3 | 1.3e-07 | -0.93 | 0.02 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SGEF | 0.04 | 0.04 | enet | 12 | 0.04 | 1.1e-05 | -4.6 | 5.2 | 1.7e-07 | -0.90 | 0.04 | 0.93 | FALSE |