[Hub]/) : Traits : Chronotype (morning person) :

chr9:131,169,528-132,569,553

Best TWAS P=7.9e-10 · Best GWAS P=5.24e-10 conditioned to 0.00393

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum CRAT 0.35 0.27 lasso 8 0.27 1.1e-08 4.9 -5.2 2.2e-07 -0.42 0.72 0.27 FALSE
2 GTEx Cells Transformed fibroblasts RP11-247A12.1 0.07 0.04 enet 8 0.04 5.0e-04 5.3 -5.1 2.7e-07 -0.39 0.25 0.51 FALSE
3 GTEx Heart Left Ventricle RP11-247A12.1 0.14 0.11 lasso 5 0.13 1.7e-07 5.0 -5.3 9.5e-08 -0.38 0.70 0.22 FALSE
4 GTEx Stomach CRAT 0.26 0.10 lasso 7 0.08 1.6e-04 4.9 -5.2 1.5e-07 -0.41 0.49 0.29 FALSE
5 The Cancer Genome Atlas Glioblastoma Multiforme PPP2R4 0.16 0.04 blup 42 0.08 2.3e-03 4.7 -6.2 7.9e-10 -0.66 0.02 0.69 TRUE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma IER5L 0.02 0.03 lasso 2 0.02 1.1e-03 5.5 -5.5 3.5e-08 -0.44 0.06 0.50 FALSE
7 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PPP2R4 0.06 0.05 blup 41 0.08 3.7e-05 5.0 -5.3 1.4e-07 -0.55 0.32 0.45 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma CRAT 0.03 0.04 blup 31 0.03 1.6e-04 5.0 -5.2 2.2e-07 -0.40 0.01 0.98 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma PPP2R4 0.03 0.01 blup 40 0.03 2.9e-04 4.9 -5.7 9.7e-09 -0.64 0.04 0.90 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma PPP2R4 0.07 0.04 blup 45 0.03 1.8e-02 5.3 -5.6 1.7e-08 -0.51 0.04 0.26 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma CRAT 0.02 0.02 blup 31 0.02 4.5e-03 4.8 -5.1 2.7e-07 -0.43 0.02 0.82 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma CRAT 0.07 0.06 blup 29 0.08 3.1e-06 4.9 -5.3 1.4e-07 -0.45 0.02 0.97 FALSE