Best TWAS P=1.31e-18 · Best GWAS P=1.14e-25 conditioned to 4.33e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | ALG10 | 0.06 | 0.04 | lasso | 6 | 0.02 | 3.5e-02 | 6.2 | -5.3 | 1.4e-07 | 0.50 | 0.60 | 0.04 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | ALG10 | 0.05 | 0.04 | lasso | 2 | 0.04 | 5.6e-04 | 6.9 | -7.6 | 3.9e-14 | 0.69 | 0.87 | 0.03 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | SYT10 | 0.18 | 0.04 | enet | 25 | 0.12 | 1.4e-14 | -4.8 | 6.0 | 2.4e-09 | -0.49 | 1.00 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ALG10 | 0.02 | 0.02 | enet | 3 | 0.02 | 8.0e-05 | 7.1 | -5.8 | 5.0e-09 | 0.51 | 0.40 | 0.05 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ALG10 | 0.07 | 0.07 | blup | 26 | 0.07 | 1.1e-08 | 7.1 | -5.6 | 1.7e-08 | 0.48 | 1.00 | 0.00 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | ALG10 | 0.11 | 0.06 | enet | 8 | 0.08 | 4.1e-05 | 7.1 | -5.3 | 1.0e-07 | 0.45 | 0.24 | 0.09 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ALG10 | 0.06 | 0.04 | blup | 26 | 0.05 | 3.0e-06 | 7.1 | -8.8 | 1.3e-18 | 0.80 | 0.02 | 0.97 | TRUE |
| 8 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | ALG10 | 0.12 | -0.01 | blup | 26 | 0.02 | 8.9e-02 | 7.2 | -8.1 | 7.8e-16 | 0.73 | 0.02 | 0.28 | FALSE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | ALG10 | 0.13 | 0.04 | lasso | 1 | 0.04 | 1.4e-04 | 7.1 | -7.1 | 1.4e-12 | 0.62 | 0.43 | 0.09 | FALSE |