TWAS hub - SYT10

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.365	0.0540	0.0e+00	0.140	0.272	0.275	0.283	0.275	1.2e-16	3.6e-33	1.8e-33	1.4e-34	1.6e-33
2	ROSMAP	Brain Pre-frontal Cortex	0.180	0.0438	1.1e-11	0.036	0.105	0.115	0.108	0.113	1.8e-05	2.3e-13	1.4e-14	8.7e-14	2.5e-14

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Chronotype (morning person)	13.1	30.3	35.6	5.0	6.0
Illnesses of father: High blood pressure	10.5	13.0	13.9	3.5	3.7
Medication: Ventolin 100micrograms inhaler	9.9	12.6	13.1	3.6	3.5
Pulse rate, automated reading	7.9	25.4	41.1	3.1	6.4
Worrier / anxious feelings	6.6	12.5	17.5	4.2	2.7
Lupus	6.2	9.3	11.2	-3.4	-2.7
Depression (self-reported)	5.4	6.5	8.6	-2.9	-2.1
Pulse rate	5.2	8.8	14.3	1.8	3.8
Chronic bronchitis/emphysema (mother)	5.1	5.9	6.2	-2.5	-2.4
Hearing difficulty/problems: Yes	4.7	7.2	10.4	3.2	2.0
Worry too long after embarrassment	4.7	8.0	10.8	3.3	2.3
Illnesses of father: None of the above (group 1)	4.5	5.5	6.1	-2.2	-2.5
Medication for hormone replacement therapy	3.7	4.2	4.7	1.9	2.2
Medication for pain relief, constipation, heartburn	3.5	5.9	7.1	-2.7	-2.2
Ever used hormone-replacement therapy (HRT)	3.4	4.3	4.6	2.0	2.2
Sensitivity / hurt feelings	3.3	5.7	7.8	2.8	1.9
Father’s age at death	3.2	4.3	5.3	-1.8	-2.3
Birth weight of first child	3.2	5.9	6.4	-2.3	-2.5
Medication: Lisinopril	3.2	4.2	4.5	2.1	2.0
Handedness (chirality/laterality): Left-handed	3.1	3.7	4.2	2.0	1.8
Medication: Lansoprazole	3.0	3.4	3.5	1.8	1.9
Alcohol intake versus 10 years previously	2.9	4.3	5.2	-2.3	-1.8
Had major operations	2.9	3.4	4.0	-1.7	-2.0
Hair/balding pattern: Pattern 3	2.8	4.2	4.5	-2.1	-1.9
Worry (Nagel 2018)	2.7	5.7	9.1	3.0	1.5
Number of treatments/medications taken	2.7	4.8	4.9	2.1	2.2
Alcohol intake frequency.	2.6	6.1	6.6	-2.6	-2.4
Neuroticism	2.5	5.9	8.8	3.0	1.7
Asthma	2.5	4.9	5.8	2.4	2.0
Number of children fathered	2.5	2.8	3.1	-1.8	-1.6
Alcohol drinker status: Never	2.5	3.0	3.6	-1.6	-1.9
Nervous feelings	2.4	4.5	7.1	2.7	1.4
Medication: Ibuprofen	2.4	2.8	4.5	1.1	2.1
Medication: Omeprazole (e.g. Zanprol)	2.4	2.9	3.8	2.0	1.4
Mouth/teeth dental problems: Loose teeth	2.2	2.6	3.0	1.7	1.5
Medication: Aspirin	2.2	2.9	5.1	2.3	0.9
Asthma (self-reported)	2.2	4.4	5.4	2.3	1.8
Wears glasses or contact lenses	2.2	2.6	2.9	-1.5	-1.7
Supplements: Fish oil (including cod liver oil)	2.2	2.9	3.0	1.7	1.7
Average weekly champagne plus white wine intake	2.1	2.8	3.0	1.6	1.7
Risk taking	2.1	3.0	3.1	-1.8	-1.7
Maternal smoking around birth	2.0	2.9	3.4	1.8	1.6
Frequency of depressed mood in last 2 weeks	1.9	2.6	3.7	-1.2	-1.9
Medication: Omeprazole	1.9	2.3	2.6	1.4	1.6
Diastolic blood pressure, automated reading	1.9	6.0	7.8	2.0	2.8
Medication: Co-codamol	1.8	2.1	3.0	1.7	1.1
Medication: Atenolol	1.8	2.2	2.9	1.7	1.2
Number of full brothers	1.8	2.3	2.4	-1.6	-1.4
Emphysema/chronic bronchitis	1.8	2.0	2.7	1.6	1.2
Medication: Seretide 50 evohaler	1.8	2.0	3.3	1.8	0.8
Bipolar Disorder (2011)	1.7	1.7	2.3	-1.5	-1.1
High blood pressure (mother)	1.7	2.4	3.2	1.8	1.3
Mother’s age at death	1.7	2.2	2.6	-1.6	-1.3
Depression (Nagel 2018)	1.6	2.4	2.8	-1.4	-1.7
Primary Biliary Cirrhosis	1.6	2.3	2.9	-1.3	-1.7
Systolic Blood Pressure	1.6	7.9	9.9	3.1	2.5
Fasting Glucose	1.5	1.8	2.5	1.1	1.6
Neuroticism (2016)	1.5	2.2	4.1	-0.6	-2.0
Cardiovascular Disease	1.5	5.0	8.0	2.8	1.4
Neuroticism score	1.5	3.0	4.2	2.1	1.3
Breastfed as a baby	1.5	1.9	2.0	-1.4	-1.3
Pulse wave reflection index	1.5	1.9	2.8	-1.0	-1.7
Headache pain in last month	1.5	2.7	3.5	-1.4	-1.9
Medication: Allopurinol	1.5	2.0	3.7	0.5	1.9
Miserableness	1.5	2.6	3.3	-1.4	-1.8
Medication: Ramipril	1.4	1.7	3.1	1.8	0.6
Health satisfaction	1.4	1.8	2.4	-1.6	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	2.9	3.3	-1.6	-1.8
Heart attack/myocardial infarction (self-reported)	1.4	1.8	3.0	1.7	0.7
Heart attack	1.3	1.7	3.0	1.7	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	2.0	-1.4	-1.2
Medication: Aspirin	1.3	1.7	3.3	1.8	0.3
Medication: Paracetamol	1.3	2.0	2.1	1.4	1.5
Schizophrenia (2018)	1.2	2.5	3.0	-1.7	-1.4
Ulcerative Colitis	1.2	1.7	2.1	-1.1	-1.5
Medication: Paracetamol	1.2	2.0	2.3	1.5	1.3
Medication for cholesterol	1.2	1.9	2.4	-1.5	-1.2
Breast cancer (self-reported)	1.2	1.5	2.5	-1.6	-0.7
Cholesterol lowering medication	1.2	1.7	2.9	1.7	0.8
Blood White Count	1.1	7.9	9.0	3.0	2.6
Prospective memory result	1.1	1.4	1.6	1.3	1.1
Medication: Gliclazide	1.1	1.2	1.6	-1.3	-0.9
Lung FEV1/FVC ratio	1.0	5.3	5.3	2.3	2.3
Had menopause	1.0	1.2	1.6	-1.3	-0.9
Shortness of breath walking on level ground	1.0	1.2	1.7	0.8	1.3
Angina (self-reported)	1.0	1.3	2.6	1.6	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.1	1.4	-0.9	-1.2
Loneliness, isolation	1.0	1.4	2.4	-0.7	-1.5
Commuting to job workplace: Public transport	1.0	1.1	1.6	0.8	1.3
Pain experienced in last month	1.0	1.7	2.3	-1.0	-1.5
Supplements: Zinc	0.9	1.0	1.4	-0.7	-1.2
Diabetes (mother)	0.9	1.2	2.1	1.4	0.6
Taking other prescription medications	0.9	1.4	1.9	1.4	0.9
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	1.8	0.6	1.3
Past tobacco smoking	0.9	1.6	2.8	-0.6	-1.7
Medication: Simvastatin	0.9	1.3	2.2	1.5	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.1	1.9	0.5	1.4
Glaucoma (self-reported)	0.8	0.9	1.2	-0.8	-1.1
Migraine (self-reported)	0.8	1.0	1.9	-1.4	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	1.0	1.0	1.0
Mineral and other dietary supplements	0.8	1.1	1.2	-1.0	-1.1
Eye problems/disorders: Glaucoma	0.8	1.0	1.0	-1.0	-1.0
Mean Putamen Volume	0.7	0.8	1.2	-1.1	-0.7
Respiratory disease	0.7	1.5	2.3	1.5	0.8
Angina	0.7	1.0	1.9	1.4	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	1.1	-1.0	-0.9
Age when periods started (menarche)	0.7	1.8	2.7	-1.6	-0.9
Medication: Levothyroxine sodium	0.7	1.2	1.4	-1.0	-1.2
Hair/balding pattern: Pattern 2	0.7	0.9	1.1	0.8	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.6	1.2	-0.3
Medication: Blood pressure	0.7	1.2	1.9	1.4	0.6
Mean time to correctly identify matches	0.7	1.3	1.6	-1.3	-1.0
Overall health rating	0.7	1.5	2.2	-0.9	-1.5
Hypertension (Self-reported)	0.7	1.9	2.8	1.7	1.1
Qualifications: nursing, teaching	0.7	1.1	1.3	-1.1	-1.0
Guilty feelings	0.7	1.1	1.6	1.3	0.8
High cholesterol (Self-reported)	0.7	1.2	2.3	1.5	0.3
Vascular/heart problems diagnosed by doctor	0.7	2.0	3.6	-1.9	-0.7
Heart disease (siblings)	0.7	0.9	1.8	1.3	0.0
Bipolar Disorder (2018)	0.6	0.9	1.5	0.6	1.2
Neuroticism (Nagel 2018)	0.6	1.5	2.8	1.7	0.5
Age at First Birth	0.6	0.8	1.3	-0.5	-1.2
BMI	0.6	3.6	6.3	2.5	0.9
Qualifications: CSEs or equivalent	0.6	0.8	1.4	0.4	1.2
High blood pressure	0.6	1.8	2.6	1.6	1.0
Allergy	0.6	1.3	1.6	-1.3	-1.0
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	1.0	-1.0	-0.8
Lung cancer (father)	0.6	0.7	1.2	1.1	0.3
Gout (self-reported)	0.6	0.8	1.5	0.1	1.2
Leg pain on walking	0.6	0.8	1.0	1.0	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	0.6	-0.8	-0.8
Eye problems/disorders: Cataract	0.6	0.7	0.9	0.7	0.9
Financial situation satisfaction	0.6	0.7	1.3	1.1	0.2
Medication: Blood pressure	0.6	1.1	1.2	1.0	1.1
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.0	0.6	-1.0
Irritable Bowel Disease (IBD)	0.5	1.3	1.4	-1.1	-1.2
Verbal and Numeric Reasoning (VNR)	0.5	1.3	2.4	-1.5	-0.5
Schizophrenia (2014)	0.5	1.1	1.4	-1.2	-0.9
Diabetes (father)	0.5	0.6	1.2	1.1	-0.1
Severe depression (siblings)	0.5	0.6	0.7	0.8	-0.7
Stomach or abdominal pain in last month	0.5	0.6	1.2	-1.1	0.1
Hearing difficulty/problems with background noise	0.5	0.7	1.2	1.1	0.5
Time employed in main current job	0.5	0.6	0.9	-0.5	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	1.3	1.1	0.6
Forced vital capacity (FVC), Best measure	0.5	1.9	3.0	-1.7	-0.9
Exposure to tobacco smoke outside home	0.5	0.6	0.7	-0.8	-0.8
Number of full sisters	0.5	0.7	0.7	-0.8	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	0.9	-0.6	-1.0
Illnesses of siblings: Diabetes	0.5	0.6	1.2	1.1	0.3
Average weekly red wine intake	0.5	0.8	0.9	1.0	0.8
Ever had bowel cancer screening	0.5	0.6	1.1	-0.2	-1.1
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.2	1.1	-0.1
Alzheimer’s Disease (in father)	0.4	0.5	0.9	0.9	-0.2
Crohns Disease (2017)	0.4	0.9	1.1	-0.9	-1.0
Body Mass Index (BMI) (2010)	0.4	0.6	0.9	0.5	1.0
Relative age of first facial hair	0.4	0.8	1.5	-1.2	-0.4
Relative age voice broke	0.4	0.6	1.1	-1.0	-0.3
Waist circumference	0.4	1.3	2.4	1.5	0.5
Qualifications: None of the above	0.4	0.9	1.5	-1.2	-0.5
Illnesses of siblings	0.4	0.5	1.0	-1.0	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	0.8	-0.9	-0.7
Happiness	0.4	0.5	0.5	-0.7	-0.7
Tense / ‘highly strung’	0.4	0.7	1.2	1.1	0.5
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	0.9	0.9	0.3
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.2	-1.1	-0.3
Suffer from ‘nerves’	0.4	0.7	1.3	1.1	0.3
Osteoporosis (self-reported)	0.4	0.4	0.5	-0.7	-0.6
Blood Red Count	0.3	2.5	3.6	1.9	1.2
Waist Hip Ratio (WHR)	0.3	1.5	1.7	1.3	1.1
Systolic blood pressure, automated reading	0.3	0.7	1.2	1.1	0.5
Hand grip strength (right)	0.3	0.8	1.7	-1.3	0.0
Average weekly fortified wine intake	0.3	0.4	0.8	-0.2	0.9
Alcohol usually taken with meals	0.3	0.4	0.8	0.3	0.9
Forced vital capacity (FVC)	0.3	1.0	1.8	-1.3	-0.4
Mouth/teeth dental problems	0.3	0.4	0.8	-0.9	-0.2
Falls in the last year	0.3	0.4	0.7	-0.9	-0.3
Pulse wave Arterial Stiffness index	0.3	0.3	0.4	-0.6	-0.5
Length of working week for main job	0.3	0.4	0.7	-0.0	0.9
Medication: Amlodipine	0.3	0.4	0.6	0.8	0.4
Age at first live birth	0.3	0.6	0.9	-0.9	-0.6
Heart disease (mother)	0.3	0.3	0.5	-0.4	-0.7
Smoking status: Previous	0.3	0.4	0.8	0.1	0.9
Friendships satisfaction	0.3	0.4	0.7	-0.2	0.9
Ever smoked	0.3	0.5	0.7	-0.5	0.9
Leg fat percentage (left)	0.3	1.0	1.9	1.4	0.2
Commuting to job workplace: Cycle	0.3	0.4	0.6	-0.4	-0.8
Leg fat mass (left)	0.3	1.0	1.9	1.4	0.3
Bipolar Disorder or Schizophrenia	0.2	0.5	1.0	-1.0	-0.3
Depressed Affect (Nagel 2018)	0.2	0.4	0.4	-0.5	-0.7
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.4	-1.2	-0.3
Ulcerative Colitis (UC)	0.2	0.3	0.4	-0.6	-0.6
Ovarian Cancer	0.2	0.3	0.4	0.4	0.6
HbA1C	0.2	0.2	0.3	-0.3	0.5
LDL Cholesterol	0.2	0.3	0.5	0.7	-0.2
Blood Platelet Count	0.2	2.0	2.9	1.1	1.7
Height	0.2	4.3	5.4	-2.3	-1.8
Smoking Status	0.2	0.5	0.9	0.2	0.9
Hypothyroidism (self reported)	0.2	0.5	0.6	-0.8	-0.6
Type 2 Diabetes (T2D) (2018)	0.2	0.3	0.4	-0.6	-0.5
Lung FVC	0.2	1.2	1.5	-1.0	-1.2
Tanning	0.2	2.2	4.0	-0.7	-2.0
Average weekly spirits intake	0.2	0.2	0.4	-0.1	-0.7
Impedance of leg (right)	0.2	1.1	1.3	-1.2	-1.0
Townsend deprivation index at recruitment	0.2	0.2	0.3	-0.6	-0.4
Chronic bronchitis/emphysema (father)	0.2	0.2	0.3	-0.3	0.5
Body mass index (BMI)	0.2	1.0	1.9	1.4	0.3
Diabetes (self-reported)	0.2	0.4	0.5	0.5	0.7
Arm fat percentage (right)	0.2	0.7	1.5	1.2	0.1
Number of live births	0.2	0.2	0.3	-0.4	-0.6
Qualifications: A levels/AS levels or equivalent	0.2	0.5	0.7	0.8	0.5
Medication: Cholesterol lowering	0.2	0.3	0.7	0.8	-0.2
Illnesses of mother	0.2	0.3	0.3	-0.5	-0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	1.2	-1.1	-0.5
Arm fat mass (right)	0.2	0.6	1.3	1.1	0.2
Standing height	0.2	1.9	2.9	-1.7	-1.0
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.5	-0.7	-0.3
High blood pressure (siblings)	0.2	0.3	0.6	-0.0	-0.8
Body fat percentage	0.2	0.9	1.7	1.3	-0.0
Leg fat percentage (right)	0.2	0.7	1.4	1.2	0.2
Eye problems/disorders: None of the above	0.2	0.3	0.4	-0.6	-0.4
Leg fat mass (right)	0.2	0.8	1.6	1.3	0.2
Comparative height size at age 10	0.2	0.9	1.7	0.4	1.3
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.4	0.6	-0.3
Supplements: Vitamin C	0.2	0.3	0.5	0.7	-0.3
Arm fat percentage (left)	0.2	0.7	1.4	1.2	0.2
Commuting to job workplace: Walk	0.2	0.2	0.4	-0.7	0.0
Mouth/teeth dental problems: Mouth ulcers	0.2	0.2	0.4	0.6	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.4	-0.6	0.1
Arm fat mass (left)	0.2	0.6	1.2	1.1	0.1
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.5	0.3	0.7
Medication: Bendroflumethiazide	0.2	0.3	0.4	-0.4	-0.6
Number of operations (self-reported)	0.2	0.3	0.4	-0.4	-0.6
Average weekly beer plus cider intake	0.2	0.3	0.3	-0.5	0.6
Myopia	0.2	0.3	0.4	-0.7	-0.3
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	-0.3	0.4
Reaction Time	0.1	0.2	0.3	-0.5	-0.3
Coronary Artery Disease (CAD)	0.1	0.1	0.1	-0.3	-0.1
HDL Cholesterol	0.1	0.2	0.4	-0.2	-0.7
Triglycerides	0.1	0.2	0.3	0.6	0.2
Blood Eosinophil Count	0.1	0.5	0.5	0.7	0.7
Hand grip strength (left)	0.1	0.2	0.3	-0.5	0.5
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.2	-0.0	0.5
Ever had hysterectomy (womb removed)	0.1	0.1	0.2	0.4	0.1
Medication: Metformin	0.1	0.1	0.1	0.4	0.1
Trunk fat percentage	0.1	0.5	1.0	1.0	-0.3
Current tobacco smoking	0.1	0.2	0.4	-0.6	-0.0
Fed-up feelings	0.1	0.1	0.1	0.3	0.4
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.2	0.2	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.1	0.1	-0.3	-0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.1	0.3	0.1
Serious illness, injury or assault to yourself	0.1	0.1	0.1	-0.3	-0.3
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.3	0.1	0.5
Impedance of leg (left)	0.1	0.6	0.6	-0.8	-0.8
Trunk fat mass	0.1	0.4	0.8	0.9	-0.3
Number of incorrect matches in round	0.1	0.2	0.3	-0.2	0.5
Impedance of arm (right)	0.1	0.4	0.5	-0.7	-0.6
Trunk fat-free mass	0.1	0.3	0.4	-0.6	-0.5
Noisy workplace	0.1	0.2	0.2	-0.5	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.1	-0.3	0.2
Impedance of arm (left)	0.1	0.3	0.5	-0.7	-0.4
Trunk predicted mass	0.1	0.4	0.5	-0.7	-0.5
Exposure to tobacco smoke at home	0.1	0.1	0.1	-0.3	0.3
Hair/balding pattern: Pattern 4	0.1	0.3	0.4	0.6	-0.5
Peak expiratory flow (PEF)	0.1	0.3	0.4	0.3	0.6
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.2	-0.1	0.4
Blood clot in the leg (DVT)	0.1	0.1	0.2	0.4	-0.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.3	-0.2	-0.5
Birth weight	0.1	0.1	0.3	-0.5	0.2
Comparative body size at age 10	0.1	0.2	0.2	0.3	-0.5
Wheeze or whistling in the chest in last year	0.1	0.1	0.2	0.2	0.4
Pulse wave peak to peak time	0.1	0.1	0.1	0.3	0.2
Qualifications: College or University degree	0.1	0.2	0.3	0.6	0.1
Neck or shoulder pain in last month	0.1	0.2	0.2	0.5	0.4
Whole body fat mass	0.1	0.5	1.0	1.0	-0.1
Chest pain or discomfort	0.1	0.1	0.2	0.4	0.1
Family relationship satisfaction	0.1	0.1	0.1	-0.2	0.3
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.1	-0.4	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.2	0.3	0.4
Leg fat-free mass (right)	0.1	0.3	0.5	0.7	0.4
Long-standing illness, disability or infirmity	0.1	0.1	0.2	-0.4	-0.1
Back pain experienced in last month	0.1	0.2	0.2	-0.3	0.5
Osteoarthritis (self-reported)	0.1	0.1	0.2	0.2	0.4
Smoking status: Current	0.1	0.1	0.2	-0.5	0.1
Leg predicted mass (right)	0.1	0.4	0.5	0.7	0.4
Number of self-reported non-cancer illnesses	0.1	0.2	0.3	0.6	0.3
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.1	-0.4
Hearing aid user	0.1	0.1	0.2	0.5	-0.2
Medication: Atorvastatin	0.1	0.1	0.2	-0.0	-0.4
Irritability	0.1	0.2	0.3	-0.3	-0.6
Fractured/broken bones in last 5 years	0.1	0.2	0.2	-0.4	0.4
Age started oral contraceptive pill	0.1	0.2	0.3	0.1	-0.6
Supplements: Calcium	0.1	0.1	0.2	-0.5	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	0.4	-0.3
Impedance of whole body	0.1	0.4	0.5	-0.7	-0.6
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	-0.1	-0.1
Alzheimer’s Disease (including proxy)	0.0	0.1	0.1	-0.2	-0.3
Major Depression (MDD)	0.0	0.0	0.0	0.0	-0.2
Breast Cancer	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.1	0.1	-0.3	-0.2
Rheumatoid Arthritis	0.0	0.0	0.0	-0.1	0.1
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.2	0.0
Heel T-Score	0.0	0.1	0.2	0.3	0.4
Allergy or Eczema	0.0	0.0	0.0	-0.1	-0.0
Hair Pigment	0.0	0.0	0.1	-0.2	0.2
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.1	0.3	0.0
Vitamin and mineral supplements	0.0	0.0	0.0	0.1	0.2
Pack years adult smoking proportion	0.0	0.0	0.1	0.3	-0.1
Leg fat-free mass (left)	0.0	0.1	0.2	0.4	0.1
Multivitamins +/- minerals	0.0	0.0	0.0	-0.0	0.0
Supplements: Glucosamine	0.0	0.0	0.0	0.1	-0.1
Sitting height	0.0	0.3	0.4	-0.6	-0.4
Leg predicted mass (left)	0.0	0.1	0.2	0.4	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.0	0.0	-0.1	-0.2
Had other major operations	0.0	0.1	0.1	-0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.1	-0.4	-0.1
Ever unenthusiastic/disinterested for a whole week	0.0	0.0	0.0	-0.2	-0.2
Financial difficulties in last 2 years	0.0	0.0	0.0	0.1	0.1
Pain all over the body in last month	0.0	0.0	0.0	0.2	-0.0
Fluid intelligence score	0.0	0.1	0.1	-0.3	0.2
Weight	0.0	0.2	0.4	0.6	-0.1
Hip circumference	0.0	0.1	0.3	0.5	-0.1
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.1	-0.3	0.1
Mouth/teeth dental problems: Dentures	0.0	0.0	0.0	-0.1	0.2
Loud music exposure frequency	0.0	0.0	0.0	0.1	-0.1
Arm fat-free mass (right)	0.0	0.1	0.1	-0.1	-0.3
Arm predicted mass (right)	0.0	0.0	0.0	-0.0	-0.1
Age at last live birth	0.0	0.0	0.1	0.3	0.1
Knee pain experienced in last month	0.0	0.1	0.1	0.3	0.1
Illnesses of father: Heart disease	0.0	0.0	0.1	0.3	-0.1
Whole body fat-free mass	0.0	0.0	0.0	-0.0	-0.2
Mood swings	0.0	0.0	0.0	0.2	0.1
Diabetes diagnosed by doctor	0.0	0.0	0.0	0.1	0.1
Whole body water mass	0.0	0.0	0.0	0.0	-0.1
Basal metabolic rate	0.0	0.0	0.0	0.1	-0.2
Arm fat-free mass (left)	0.0	0.2	0.4	-0.2	-0.6
Ever depressed for a whole week	0.0	0.0	0.1	0.1	-0.3
Unable to work because of sickness or disability	0.0	0.0	0.0	0.2	0.0
Basal cell carcinoma (self-reported)	0.0	0.1	0.1	0.0	0.3
Alcohol drinker status: Previous	0.0	0.0	0.0	0.2	0.2
Pack years of smoking	0.0	0.0	0.1	0.3	0.0
Arm predicted mass (left)	0.0	0.1	0.1	-0.0	-0.4

Hub : Genes

SYT10

Models

Trait associations