[Hub]/) : Traits : Chronotype (morning person) :

chr12:111,385,296-113,517,494

Best TWAS P=4.59e-08 · Best GWAS P=5.29e-09 conditioned to 0.035

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Muscularis HECTD4 0.06 0.03 lasso 4 0.02 1.8e-02 -4.8 5.3 1.0e-07 -0.82 0.11 0.82 FALSE
2 GTEx Nerve Tibial HECTD4 0.05 0.01 enet 6 0.01 3.6e-02 -5.7 5.5 4.6e-08 -0.90 0.03 0.92 TRUE
3 GTEx Skin Sun Exposed Lower leg ALDH2 0.10 0.09 enet 13 0.13 6.7e-11 -4.8 5.3 1.1e-07 -0.86 0.06 0.94 FALSE
4 GTEx Testis BRAP 0.06 0.03 enet 13 0.01 8.7e-02 -4.8 -5.2 2.1e-07 0.79 0.12 0.73 FALSE