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Chronotype (morning person)
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chr12:111,385,296-113,517,494
Best TWAS P=4.59e-08 · Best GWAS P=5.29e-09 conditioned to 0.035
111.5M
112M
112.5M
113M
113.5M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Nerve Tibial
HECTD4
0.05
0.01
enet
6
0.01
3.6e-02
-5.7
5.5
4.6e-08
-0.90
0.03
0.92
TRUE
1
GTEx
Esophagus Muscularis
HECTD4
0.06
0.03
lasso
4
0.02
1.8e-02
-4.8
5.3
1.0e-07
-0.82
0.11
0.82
FALSE
3
GTEx
Skin Sun Exposed Lower leg
ALDH2
0.10
0.09
enet
13
0.13
6.7e-11
-4.8
5.3
1.1e-07
-0.86
0.06
0.94
FALSE
4
GTEx
Testis
BRAP
0.06
0.03
enet
13
0.01
8.7e-02
-4.8
-5.2
2.1e-07
0.79
0.12
0.73
FALSE