TWAS hub - TRIAP1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.0890	0.0410	8.5e-03	-0.005	NA	0.011	NA	-0.001	7.3e-01	NA	8.5e-02	NA	3.4e-01
2	GTEx	Esophagus Gastroesophageal Junction	0.2070	0.0780	1.9e-03	0.059	NA	-0.001	NA	0.030	3.6e-03	NA	3.5e-01	NA	2.9e-02
3	GTEx	Esophagus Mucosa	0.0790	0.0330	2.9e-03	0.076	NA	0.042	NA	0.042	9.3e-06	NA	8.5e-04	NA	8.3e-04
4	GTEx	Lung	0.1221	0.0487	9.8e-04	-0.003	NA	0.055	NA	-0.003	7.2e-01	NA	4.5e-05	NA	7.9e-01
5	GTEx	Muscle Skeletal	0.0705	0.0258	4.7e-04	0.068	NA	0.051	NA	0.062	3.4e-07	NA	8.2e-06	NA	1.0e-06
6	GTEx	Skin Not Sun Exposed Suprapubic	0.0960	0.0410	4.4e-03	0.094	NA	0.086	NA	0.073	7.5e-06	NA	1.8e-05	NA	7.5e-05
7	GTEx	Skin Sun Exposed Lower leg	0.0690	0.0290	4.0e-03	0.070	NA	0.057	NA	0.069	2.1e-06	NA	1.8e-05	NA	2.4e-06
8	TCGA	Breast Invasive Carcinoma	0.0196	0.0093	2.7e-04	0.025	0.023	0.021	NA	0.024	5.3e-06	1.2e-05	3.2e-05	NA	9.2e-06
9	TCGA	Head and Neck Squamous Cell Carcinoma	0.0635	0.0237	2.7e-07	0.068	0.073	0.075	NA	0.074	4.7e-08	1.4e-08	7.6e-09	NA	1.1e-08
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0327	0.0196	9.2e-03	0.010	0.006	0.006	NA	0.010	2.3e-02	6.6e-02	5.5e-02	NA	2.2e-02
11	TCGA	Lung Adenocarcinoma	0.0391	0.0205	1.4e-03	0.024	0.020	0.013	NA	0.009	6.4e-04	1.8e-03	9.3e-03	NA	2.5e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	2	3	4	5	6	7	8	9	10	11
Diabetes (mother)	9.8	12.5	17.5	-3.3	-4.0	-1.9	-4.2	-4.0	-4.2	-4.0	-3.5	-4.1	-3.2
Smoking Status	8.7	20.7	28.5	-4.6	-5.2	-2.3	-5.1	-5.2	-5.3	-5.2	-4.7	-5.3	-3.9
Average weekly beer plus cider intake	7.2	10.4	21.8	-3.2	-3.6	-0.9	-3.5	-3.5	-3.6	-3.6	-4.7	-3.5	-2.7
Current tobacco smoking	6.6	10.8	16.0	-3.2	-3.8	-0.9	-3.7	-3.7	-3.8	-3.7	-4.0	-3.8	-2.7
Chronotype (morning person)	6.4	14.8	26.2	-4.9	-3.9	-3.4	-3.9	-3.9	-3.6	-3.9	-3.6	-3.7	-5.1
Gout (self-reported)	6.3	8.6	11.5	-3.4	-3.0	-3.3	-3.0	-3.0	-3.0	-3.0	-2.8	-3.0	-3.4
Diabetes diagnosed by doctor	5.7	9.4	12.9	-3.2	-3.4	-2.2	-3.5	-3.3	-3.6	-3.3	-3.1	-3.5	-2.9
Fractured/broken bones in last 5 years	5.3	6.9	10.0	-2.5	-3.1	-0.1	-3.1	-3.1	-2.9	-3.2	-2.9	-3.0	-2.2
Wheeze or whistling in the chest in last year	5.1	9.1	16.3	-3.0	-3.3	-1.8	-3.2	-3.2	-3.5	-3.3	-4.0	-3.4	-2.4
Smoking status: Current	5.0	8.0	11.9	-2.7	-3.2	-0.6	-3.2	-3.2	-3.4	-3.2	-3.5	-3.3	-2.2
Diabetes (self-reported)	4.9	7.5	9.6	-2.9	-2.9	-2.6	-3.1	-2.8	-3.1	-2.9	-2.8	-3.0	-2.8
Medication: Gliclazide	4.7	5.4	7.5	-2.3	-2.6	-1.2	-2.7	-2.5	-2.7	-2.6	-2.3	-2.7	-2.2
Unable to work because of sickness or disability	4.5	5.9	7.9	-2.8	-2.8	-1.0	-2.6	-2.6	-2.8	-2.7	-2.4	-2.7	-2.5
Tinnitus: Yes, but not now, but have in the past	4.3	4.6	6.3	-2.3	-2.5	-1.0	-2.5	-2.4	-2.4	-2.4	-2.2	-2.4	-2.0
Pack years adult smoking proportion	3.5	5.3	8.5	-2.2	-2.3	-2.9	-2.4	-2.3	-2.5	-2.4	-2.5	-2.4	-2.1
Hypothyroidism (self reported)	3.4	7.7	11.9	2.7	3.3	1.7	3.4	3.5	2.9	3.2	2.0	3.2	2.7
Medication: Metformin	3.4	4.8	7.1	-2.3	-2.4	-1.4	-2.5	-2.5	-2.7	-2.5	-2.4	-2.5	-1.5
Primary Biliary Cirrhosis	3.3	4.7	6.8	-2.6	-2.5	-0.8	-2.6	-2.5	-2.2	-2.4	-1.6	-2.3	-2.5
Heel bone mineral density (BMD) T-score, automated (left)	3.3	7.5	19.3	2.6	2.6	4.4	2.6	2.7	2.8	2.6	2.7	2.7	2.6
Medication: Simvastatin	3.3	4.8	8.6	-2.3	-2.3	-2.9	-2.4	-2.4	-2.4	-2.3	-1.9	-2.3	-1.6
Headache pain in last month	3.2	5.5	8.9	-2.0	-2.7	0.1	-2.6	-2.7	-3.0	-2.7	-2.8	-2.8	-1.8
Pack years of smoking	3.2	4.6	9.0	-2.2	-2.1	-3.0	-2.2	-2.1	-2.3	-2.2	-2.2	-2.2	-1.9
Alcohol intake frequency.	2.9	6.7	10.7	3.1	2.9	-1.2	2.9	2.7	2.7	2.9	2.0	2.9	3.3
Lung cancer (father)	2.8	3.3	5.3	1.7	2.1	0.7	2.1	2.3	2.0	2.2	2.1	2.1	1.2
Deep venous thrombosis (DVT) (self-reported)	2.7	3.4	6.5	2.2	1.9	0.4	2.0	1.8	1.9	2.0	2.0	2.0	2.5
Alcohol usually taken with meals	2.5	4.0	10.9	1.6	2.2	-0.0	2.0	1.9	2.1	2.2	3.3	2.1	2.0
Hypothyroidism/myxoedema (self-reported)	2.4	4.6	7.2	2.0	2.5	0.9	2.6	2.7	2.3	2.6	1.5	2.5	2.3
Body Mass Index (BMI) (2010)	2.3	3.1	6.1	-1.9	-1.9	-0.2	-2.0	-1.9	-1.8	-1.9	-2.5	-1.9	-1.7
Type 2 Diabetes (T2D) (2018)	2.3	4.2	6.0	-2.1	-2.2	-2.0	-2.4	-2.1	-2.3	-2.2	-1.9	-2.2	-2.0
Blood clot in the leg (DVT)	2.3	2.9	5.4	2.0	1.8	0.8	1.9	1.7	1.6	1.9	1.7	1.8	2.3
Age at first live birth	2.3	4.0	9.5	2.6	1.9	1.1	1.9	1.9	2.0	2.0	3.1	1.9	1.9
Emphysema/chronic bronchitis	2.3	2.6	4.3	-1.8	-1.6	-2.1	-1.6	-1.6	-1.5	-1.6	-2.0	-1.5	-1.7
Mineral and other dietary supplements	2.3	3.1	4.9	1.9	2.0	0.6	2.0	2.2	2.1	2.0	1.8	2.1	1.0
Pain type(s) experienced in last month: Hip pain	2.3	2.9	4.5	-1.8	-1.7	-1.0	-1.9	-1.7	-1.9	-1.8	-1.9	-1.8	-2.1
Average weekly fortified wine intake	2.2	2.6	6.1	1.6	1.7	0.8	1.7	1.7	1.5	1.7	2.5	1.6	1.8
Loud music exposure frequency	2.2	2.4	3.2	-1.6	-1.7	-1.7	-1.8	-1.7	-1.6	-1.6	-1.2	-1.6	-1.7
Supplements: Fish oil (including cod liver oil)	2.2	2.8	4.2	-1.9	-1.9	-0.6	-1.8	-2.1	-2.0	-1.9	-1.9	-1.9	-1.0
Sensitivity / hurt feelings	2.1	3.6	5.9	1.8	2.4	0.1	2.4	2.4	2.2	2.4	1.0	2.4	1.5
Long-standing illness, disability or infirmity	2.1	3.2	5.3	-1.8	-2.0	-0.8	-2.0	-2.0	-2.3	-2.0	-1.8	-2.2	-1.2
Mouth/teeth dental problems: Mouth ulcers	2.1	3.4	4.6	2.1	2.0	1.4	1.9	2.0	1.8	1.9	2.0	1.9	2.1
Major Depression (MDD)	2.0	2.4	3.8	-1.4	-1.7	-1.5	-1.6	-1.6	-1.7	-1.8	-1.3	-1.9	-1.4
Townsend deprivation index at recruitment	2.0	2.9	4.0	-1.8	-1.9	-0.5	-1.9	-1.9	-1.6	-1.9	-2.0	-1.8	-1.9
Shortness of breath walking on level ground	2.0	2.4	5.8	-1.6	-1.4	-2.4	-1.3	-1.3	-1.5	-1.4	-2.2	-1.4	-1.5
Medication: Allopurinol	2.0	2.7	3.9	-1.8	-1.6	-2.0	-1.6	-1.5	-1.6	-1.6	-1.7	-1.6	-1.9
Ever had prostate specific antigen (PSA) test	2.0	2.3	3.0	1.6	1.7	0.7	1.6	1.7	1.7	1.7	1.6	1.7	1.5
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.2	12.1	1.9	1.8	3.5	1.9	2.0	2.1	1.9	2.3	1.9	1.8
Birth weight	1.9	4.0	7.3	-2.7	-2.1	-1.6	-2.1	-2.3	-2.0	-2.1	-1.7	-2.0	-2.2
Chest pain or discomfort	1.9	2.8	11.5	-1.6	-1.4	-3.4	-1.3	-1.6	-1.2	-1.4	-1.8	-1.3	-1.4
Past tobacco smoking	1.8	3.3	4.9	1.5	2.1	1.1	2.1	2.0	2.2	2.1	2.2	2.2	1.1
Falls in the last year	1.8	2.5	7.3	-1.6	-1.3	-2.7	-1.5	-1.4	-1.5	-1.4	-1.9	-1.3	-1.3
Number of live births	1.8	2.6	4.2	-1.9	-1.9	0.2	-1.8	-1.9	-1.8	-1.8	-2.1	-1.7	-1.0
Intelligence (Savage-Jansen 2018)	1.7	5.1	16.2	-2.6	-2.1	-4.0	-2.2	-2.4	-1.9	-2.0	-0.4	-2.1	-2.4
Verbal and Numeric Reasoning (VNR)	1.7	4.2	7.6	-2.5	-2.1	-1.8	-2.3	-2.2	-2.1	-2.1	-1.0	-2.2	-2.8
Angina	1.7	2.2	3.1	-1.8	-1.6	-1.2	-1.5	-1.7	-1.5	-1.6	-1.6	-1.5	-1.6
Impedance of arm (right)	1.7	7.9	12.7	3.0	3.2	1.7	3.4	3.2	3.6	3.3	0.9	3.5	2.4
Depression (self-reported)	1.7	2.0	2.8	-1.6	-1.5	-1.3	-1.5	-1.4	-1.6	-1.5	-1.1	-1.6	-1.7
Tense / ‘highly strung’	1.7	2.9	5.2	1.3	2.2	-0.1	2.2	2.3	2.1	2.1	1.1	2.2	0.3
Ever smoked	1.7	2.9	4.4	-1.3	-2.0	0.3	-2.0	-1.9	-2.0	-2.1	-2.1	-2.1	-1.3
Height	1.6	30.2	49.0	4.2	6.5	4.1	6.7	7.0	6.4	6.5	4.9	6.6	3.3
Chronic bronchitis/emphysema (father)	1.6	1.9	3.3	1.3	1.6	0.8	1.5	1.8	1.5	1.7	1.2	1.6	1.0
Impedance of arm (left)	1.6	7.3	12.4	2.8	3.2	1.0	3.3	3.2	3.5	3.2	1.2	3.5	2.0
Angina (self-reported)	1.6	2.1	3.0	-1.7	-1.6	-1.1	-1.5	-1.7	-1.5	-1.6	-1.6	-1.5	-1.5
Ever had bowel cancer screening	1.6	1.8	2.9	-1.7	-1.4	-0.5	-1.4	-1.5	-1.7	-1.4	-1.5	-1.5	-1.0
Cholesterol lowering medication	1.6	2.3	3.5	-1.9	-1.5	-0.3	-1.8	-1.6	-1.8	-1.6	-1.4	-1.7	-1.8
Medication: Co-codamol	1.5	1.8	3.7	1.9	1.4	0.1	1.4	1.4	1.2	1.4	1.2	1.3	1.9
Neck or shoulder pain in last month	1.5	2.2	4.3	-0.9	-1.6	-1.9	-1.6	-1.5	-1.5	-1.6	-2.1	-1.6	-0.8
Comparative height size at age 10	1.5	8.3	13.6	2.4	3.3	1.8	3.5	3.7	3.5	3.3	3.1	3.4	1.3
Back pain experienced in last month	1.5	2.2	4.0	-1.4	-1.6	-2.0	-1.6	-1.6	-1.4	-1.5	-1.5	-1.5	-1.6
Wears glasses or contact lenses	1.5	1.7	3.8	0.6	1.4	-0.6	1.5	1.3	1.7	1.6	1.9	1.6	0.6
Systolic Blood Pressure	1.4	6.8	9.3	3.0	2.9	1.1	2.8	2.9	2.9	2.9	2.7	2.9	2.6
Qualifications: CSEs or equivalent	1.4	1.8	6.5	1.7	1.2	2.5	1.1	1.2	1.0	1.2	-0.3	1.1	1.6
Breastfed as a baby	1.4	1.8	3.2	-1.1	-1.7	-0.3	-1.7	-1.8	-1.8	-1.7	-0.7	-1.8	0.1
Medication for pain relief, constipation, heartburn	1.4	2.4	5.2	1.4	1.8	0.6	1.7	1.6	1.8	1.7	2.3	1.7	1.0
Forced expiratory volume in 1-second (FEV1), predicted	1.4	3.0	4.2	1.9	2.0	0.2	2.0	2.1	2.0	2.0	1.5	2.0	1.6
Ever taken oral contraceptive pill	1.4	1.6	2.5	-0.9	-1.5	-0.7	-1.5	-1.6	-1.4	-1.5	-1.3	-1.5	-1.0
Commuting to job workplace: Public transport	1.4	1.6	3.7	-1.6	-1.1	-1.9	-1.3	-1.3	-1.1	-1.1	-1.0	-1.1	-1.6
Hearing difficulty/problems: Yes	1.3	2.0	4.7	-1.9	-1.2	-1.5	-1.2	-1.1	-1.4	-1.2	-1.5	-1.3	-2.2
Relative age of first facial hair	1.3	2.7	4.7	2.2	1.9	1.4	1.8	2.1	1.7	2.0	0.3	1.9	1.2
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	2.6	-1.1	-1.4	-1.0	-1.5	-1.3	-1.3	-1.4	-1.6	-1.3	-1.6
Medication: Lisinopril	1.3	1.7	2.5	1.4	1.5	0.4	1.5	1.5	1.6	1.6	1.4	1.5	1.1
Number of operations (self-reported)	1.3	2.0	5.7	-1.2	-1.4	-2.4	-1.4	-1.4	-1.4	-1.5	-1.2	-1.5	-1.1
Serious illness, injury or assault to yourself	1.2	1.4	4.6	-1.1	-1.2	-2.1	-1.1	-1.2	-0.9	-1.2	-0.7	-1.1	-1.3
Health satisfaction	1.2	1.5	2.8	-1.3	-1.2	-1.5	-1.1	-1.3	-1.3	-1.2	-1.7	-1.3	-0.9
Worry (Nagel 2018)	1.1	2.2	4.3	1.1	1.8	0.1	1.9	1.9	2.0	1.8	0.7	2.1	0.7
Waist Hip Ratio (WHR)	1.1	5.1	7.3	-2.5	-2.4	-2.0	-2.5	-2.5	-2.4	-2.4	-2.7	-2.4	-1.9
Respiratory disease	1.1	2.5	3.9	-1.8	-1.7	-0.7	-1.7	-1.8	-2.0	-1.7	-1.7	-1.8	-1.2
Lung FVC	1.1	5.4	12.4	-3.3	-2.1	-3.3	-1.9	-2.4	-1.9	-2.1	-0.7	-2.0	-3.5
Average weekly spirits intake	1.1	1.3	2.2	-1.2	-1.3	-1.5	-1.3	-1.3	-1.3	-1.3	-1.0	-1.3	-0.3
Standing height	1.1	10.9	18.0	2.2	4.0	1.6	4.1	4.2	4.0	3.9	3.3	4.1	1.5
Medication: Ibuprofen	1.1	1.4	2.5	-1.0	-1.3	1.0	-1.3	-1.3	-1.2	-1.3	-1.6	-1.3	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	2.1	1.4	1.3	1.4	1.2	1.3	1.3	1.2	0.5	1.3	0.8
Overall health rating	1.1	2.4	6.6	-1.6	-1.1	-2.6	-1.2	-1.2	-1.3	-1.2	-2.5	-1.1	-1.7
BMI	1.0	5.8	10.6	-2.4	-2.5	-1.9	-2.5	-2.6	-3.2	-2.6	-2.6	-3.0	-1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	2.3	1.3	1.4	0.5	1.4	1.5	1.3	1.4	0.5	1.4	0.5
Had other major operations	1.0	1.3	2.4	-1.4	-1.2	-1.1	-1.1	-1.0	-1.1	-1.2	-1.1	-1.1	-1.6
Mouth/teeth dental problems: Bleeding gums	1.0	1.2	3.7	-1.4	-0.8	-1.9	-0.9	-0.7	-1.0	-0.8	-0.8	-0.8	-1.8
Smoking status: Previous	1.0	1.5	2.1	-1.1	-1.4	-1.1	-1.4	-1.4	-1.4	-1.4	-1.4	-1.4	-0.7
Number of self-reported non-cancer illnesses	1.0	1.8	6.7	-1.2	-1.1	-2.6	-1.1	-1.1	-1.3	-1.1	-1.6	-1.2	-0.7
Alzheimer’s Disease (including proxy)	0.9	1.4	2.9	-1.2	-1.2	-0.3	-1.2	-1.4	-1.6	-1.3	-1.2	-1.7	-0.5
Type 2 Diabetes (T2D) (2012)	0.9	1.1	1.6	1.2	1.0	1.1	0.9	1.1	1.1	1.2	1.1	0.9	1.3
Heel T-Score	0.9	6.8	30.5	2.8	2.0	5.5	2.0	2.1	1.9	2.0	1.9	1.9	3.1
Body mass index (BMI)	0.9	4.0	7.7	-1.8	-2.1	-1.9	-2.2	-2.2	-2.8	-2.2	-2.0	-2.5	-0.6
Fluid intelligence score	0.9	1.8	5.2	-1.7	-1.3	-1.4	-1.4	-1.4	-1.1	-1.3	-0.5	-1.2	-2.3
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	1.9	-0.8	-1.3	0.5	-1.2	-1.3	-1.3	-1.3	-1.4	-1.3	-0.5
Medication: Cholesterol lowering	0.9	1.4	8.1	-0.7	-0.9	-2.9	-1.0	-1.0	-1.1	-0.9	-1.0	-1.0	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	3.8	-1.0	-1.0	-1.5	-1.0	-0.7	-1.2	-1.0	-1.9	-1.0	-1.6
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	4.2	1.4	1.1	-0.1	1.1	1.0	1.5	1.0	2.0	1.2	1.1
Hearing aid user	0.9	1.1	2.5	-1.0	-1.1	-1.6	-0.9	-1.1	-1.3	-1.0	-0.8	-1.2	-0.2
High cholesterol (Self-reported)	0.9	1.6	2.5	-1.1	-1.4	-1.6	-1.4	-1.4	-1.4	-1.3	-0.9	-1.4	-1.2
Schizophrenia (2018)	0.8	1.6	2.4	-1.1	-1.6	-0.8	-1.5	-1.4	-1.2	-1.5	-1.6	-1.3	-1.3
Triglycerides	0.8	1.4	2.1	1.4	1.3	1.3	1.2	1.2	1.3	1.2	0.5	1.3	1.3
Blood White Count	0.8	5.6	8.9	3.0	2.8	0.3	2.7	2.5	2.5	2.7	1.6	2.7	2.9
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	1.5	0.8	0.9	-0.7	1.0	0.9	1.2	1.0	1.2	1.1	1.0
Nervous feelings	0.8	1.5	2.7	1.2	1.5	-0.2	1.5	1.5	1.6	1.5	0.2	1.6	0.9
Alcohol intake versus 10 years previously	0.8	1.2	4.0	-1.2	-0.9	-2.0	-0.8	-0.9	-1.0	-0.9	-1.3	-0.9	-0.9
Father’s age at death	0.8	1.0	2.6	-1.6	-1.0	1.1	-1.0	-0.9	-1.0	-1.0	-0.4	-1.0	-1.4
Medication: Lansoprazole	0.8	0.9	2.6	1.1	1.0	1.6	0.9	1.2	0.7	1.0	0.9	0.8	0.5
Pulse wave reflection index	0.8	1.0	2.8	-1.7	-1.0	0.8	-1.0	-0.9	-1.1	-1.0	-0.6	-1.1	-1.1
Number of full brothers	0.8	1.0	2.2	-1.1	-0.9	1.2	-0.8	-1.0	-0.8	-1.0	-1.5	-0.9	-1.3
Worry too long after embarrassment	0.8	1.4	5.2	-1.3	-0.8	1.2	-0.8	-0.6	-1.0	-0.8	-2.3	-0.8	-1.9
Family relationship satisfaction	0.8	0.9	1.2	1.1	1.1	1.0	1.0	1.1	0.9	1.1	0.8	1.0	1.1
Osteoporosis (self-reported)	0.8	1.0	4.2	0.8	0.8	-2.1	0.8	0.5	0.8	0.8	1.1	0.8	1.2
Ever depressed for a whole week	0.8	1.0	3.4	-0.9	-1.0	-1.8	-1.1	-1.0	-0.7	-0.9	-0.7	-0.8	-0.9
Supplements: Calcium	0.8	0.8	3.5	-1.1	-0.7	-1.9	-0.7	-0.9	-0.8	-0.7	-0.3	-0.7	-1.0
Impedance of whole body	0.8	4.2	9.1	1.8	2.4	0.8	2.5	2.5	3.0	2.4	0.8	2.8	0.6
Allergy or Eczema	0.7	1.9	3.6	-1.5	-1.3	1.7	-1.3	-1.2	-1.7	-1.2	-1.9	-1.4	-0.8
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	4.9	-0.7	-0.5	-2.2	-0.6	-0.6	-0.7	-0.5	-0.8	-0.6	-0.8
Illnesses of siblings	0.7	0.9	1.5	1.1	0.9	1.1	0.8	0.9	1.1	0.9	1.2	0.9	1.2
Medication: Omeprazole	0.7	0.8	1.9	-1.0	-1.0	-0.7	-0.9	-0.8	-0.6	-1.0	-1.4	-0.8	-1.1
Heart disease (mother)	0.7	0.8	1.8	-1.2	-0.9	-0.0	-0.9	-0.9	-1.1	-0.9	-0.6	-1.0	-1.4
Had major operations	0.7	0.9	6.0	-0.5	-0.6	-2.4	-0.6	-0.6	-0.6	-0.7	-0.6	-0.6	-0.8
Medication: Bendroflumethiazide	0.7	1.0	1.6	0.8	1.1	-1.2	1.1	1.2	1.1	1.2	1.0	1.1	0.7
Alcohol drinker status: Never	0.7	0.8	1.3	1.1	0.9	-0.9	1.1	0.8	1.1	1.0	0.7	1.0	0.8
Fasting Glucose	0.6	0.7	5.3	-0.5	0.2	-2.3	-0.0	0.2	0.0	0.1	0.2	0.1	-1.6
LDL Cholesterol	0.6	1.0	3.0	1.2	0.9	-1.7	0.8	0.9	0.9	0.8	1.1	0.9	1.1
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	3.7	-1.1	-0.8	-1.9	-0.8	-0.7	-0.6	-0.8	-0.4	-0.7	-0.8
Supplements: Glucosamine	0.6	0.8	1.6	-0.6	-1.1	0.1	-1.1	-1.3	-1.2	-1.1	-0.6	-1.2	0.6
Number of incorrect matches in round	0.6	0.9	1.8	1.4	1.1	0.9	1.0	1.1	0.9	1.1	0.4	1.0	1.1
Medication: Ramipril	0.6	0.7	1.6	-1.0	-0.9	-1.1	-0.6	-0.8	-0.7	-0.8	-1.3	-0.8	-0.8
Medication: Paracetamol	0.6	1.1	1.9	-0.8	-1.2	-0.1	-1.2	-1.1	-1.2	-1.2	-1.4	-1.2	-0.9
Medication: Amlodipine	0.6	0.9	1.5	-1.0	-1.1	-0.3	-1.1	-1.2	-1.0	-1.2	-0.8	-1.1	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	4.7	-0.9	-0.4	-2.2	-0.4	-0.3	-0.5	-0.5	-0.9	-0.5	-1.2
Number of children fathered	0.6	0.7	4.9	0.1	0.5	2.2	0.7	0.7	0.5	0.5	0.4	0.6	-0.0
Supplements: Vitamin C	0.6	0.7	1.1	0.6	1.0	-0.6	1.1	0.9	0.8	0.9	0.9	0.9	0.5
Illnesses of siblings: Diabetes	0.6	0.8	1.8	-1.2	-0.9	0.5	-0.8	-0.9	-0.9	-0.9	-0.6	-0.9	-1.3
Osteoarthritis (self-reported)	0.6	0.8	4.1	-1.1	-0.5	-2.0	-0.4	-0.4	-0.6	-0.4	-0.8	-0.5	-1.0
Basal cell carcinoma (self-reported)	0.6	0.8	1.3	0.6	0.9	-1.0	1.2	0.9	1.1	0.9	0.9	1.0	0.4
Bipolar Disorder or Schizophrenia	0.5	1.3	1.9	-0.9	-1.3	-1.3	-1.4	-1.2	-1.3	-1.4	-0.6	-1.4	-0.5
Neuroticism (2016)	0.5	0.8	1.4	1.0	1.1	-0.3	1.1	1.2	0.8	1.1	0.1	1.0	0.9
Neuroticism	0.5	1.2	2.5	0.3	1.5	-0.3	1.4	1.6	1.3	1.5	0.0	1.5	-0.4
Systolic blood pressure, automated reading	0.5	1.4	2.0	1.3	1.3	1.4	1.2	1.3	1.0	1.3	0.9	1.2	1.3
Hayfever, allergic rhinitis or eczema	0.5	1.1	3.3	-0.8	-0.9	1.8	-0.9	-0.8	-1.2	-0.9	-1.7	-1.0	-0.2
Stomach or abdominal pain in last month	0.5	0.6	3.9	-0.4	-0.6	-2.0	-0.5	-0.4	-0.7	-0.5	-0.8	-0.6	-0.3
High blood pressure (mother)	0.5	0.6	1.2	1.0	1.0	-0.2	0.9	1.0	1.1	0.9	0.7	1.0	0.0
Waist circumference	0.5	1.8	4.4	-1.4	-1.2	-2.1	-1.2	-1.3	-1.8	-1.2	-1.4	-1.5	-0.2
Hair/balding pattern: Pattern 2	0.5	0.7	4.1	-0.5	-0.2	-2.0	-0.4	-0.2	-0.1	-0.3	-0.6	-0.1	-1.5
Exposure to tobacco smoke at home	0.5	0.6	1.6	0.5	0.8	-1.3	0.9	0.6	0.7	0.8	0.1	0.8	0.8
Pulse wave peak to peak time	0.5	0.5	0.8	0.8	0.8	0.8	0.8	0.7	0.8	0.8	0.9	0.8	0.2
Medication: Seretide 50 evohaler	0.5	0.5	1.8	-0.4	-0.6	-0.7	-0.7	-0.7	-0.9	-0.7	-1.3	-0.8	-0.4
Pulse rate, automated reading	0.5	1.7	4.2	-0.8	-1.3	-2.0	-1.4	-1.5	-1.6	-1.2	-1.3	-1.4	-0.3
Number of full sisters	0.5	0.6	2.0	-1.0	-0.8	-1.4	-0.6	-0.7	-0.7	-0.8	-0.5	-0.7	-0.5
Average weekly red wine intake	0.5	0.7	3.5	0.4	0.7	1.1	0.8	0.8	0.6	0.7	1.9	0.5	0.2
Friendships satisfaction	0.5	0.6	1.5	0.6	0.9	0.2	0.9	1.1	0.8	0.9	1.2	0.8	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	2.9	-1.7	-0.8	-1.2	-0.9	-1.1	-0.8	-0.8	-0.1	-0.8	-1.7
Pain experienced in last month	0.5	0.8	2.5	0.5	0.9	0.5	1.0	0.8	0.9	0.9	1.6	0.9	0.6
Schizophrenia vs Biploar Disorder	0.4	0.5	3.5	-0.2	0.1	1.9	0.2	0.1	0.2	0.2	-1.1	0.3	-0.5
Reaction Time	0.4	0.8	2.1	1.3	0.8	-0.9	0.9	0.9	0.6	0.9	0.7	0.7	1.5
Age at First Birth	0.4	0.6	4.8	0.7	0.4	2.2	0.4	0.4	0.1	0.3	0.3	0.3	0.7
Coronary Artery Disease (CAD)	0.4	0.5	2.0	0.6	0.6	1.4	0.5	0.5	0.8	0.6	0.2	0.8	0.3
HbA1C	0.4	0.5	4.3	-0.4	-0.4	-2.1	-0.3	-0.4	-0.2	-0.4	-0.1	-0.3	-0.4
Schizophrenia (2014)	0.4	1.0	1.4	-0.9	-1.2	-0.5	-1.2	-1.0	-1.1	-1.1	-1.1	-1.1	-0.9
Lung FEV1/FVC ratio	0.4	1.8	14.2	-0.0	-0.6	3.8	-0.6	-0.5	-1.0	-0.6	-1.5	-0.8	0.4
Hand grip strength (left)	0.4	1.0	6.4	1.2	0.7	2.5	0.7	0.8	0.5	0.7	0.5	0.6	0.5
Frequency of depressed mood in last 2 weeks	0.4	0.5	3.3	-0.5	-0.4	-1.8	-0.5	-0.4	-0.6	-0.4	-0.6	-0.5	-0.8
Medication: Levothyroxine sodium	0.4	0.6	1.5	0.7	0.8	0.4	0.9	0.9	0.7	0.9	0.5	0.8	1.2
Hearing difficulty/problems with background noise	0.4	0.6	2.4	-1.0	-0.3	-1.4	-0.3	-0.3	-0.4	-0.4	-1.0	-0.3	-1.5
Qualifications: None of the above	0.4	0.9	5.4	-0.6	-0.6	0.8	-0.6	-0.7	-0.9	-0.6	-2.3	-0.7	-0.3
Mouth/teeth dental problems	0.4	0.6	1.1	1.0	0.7	0.8	0.8	0.7	0.8	0.7	0.9	0.7	0.8
Neuroticism score	0.4	0.7	1.6	0.5	1.2	0.1	1.1	1.3	1.0	1.1	-0.5	1.1	-0.2
Worrier / anxious feelings	0.4	0.8	1.5	0.9	1.1	0.3	1.1	1.2	1.1	1.1	-0.0	1.2	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	1.1	0.8	1.0	-0.8	0.9	1.0	0.9	1.0	-0.0	1.0	0.3
Mouth/teeth dental problems: Dentures	0.4	0.7	1.2	-0.7	-1.1	0.1	-1.1	-1.0	-1.0	-1.0	-1.0	-1.0	-0.2
Prospective memory result	0.4	0.4	0.7	0.7	0.8	0.5	0.7	0.7	0.8	0.8	0.0	0.8	0.7
Leg fat percentage (right)	0.4	1.3	2.4	-1.2	-1.0	-1.4	-1.0	-1.0	-1.3	-1.1	-1.6	-1.2	-0.7
Comparative body size at age 10	0.4	1.2	11.9	-0.3	0.0	-3.5	-0.0	-0.3	0.1	-0.1	0.9	-0.0	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.0	0.5	0.6	0.5	0.7	0.6	0.9	0.6	1.0	0.7	0.5
Eye problems/disorders: None of the above	0.4	0.4	1.4	-0.3	-0.7	-1.2	-0.7	-0.9	-0.6	-0.7	-0.1	-0.7	-0.4
Age at last live birth	0.4	0.7	2.4	1.2	0.6	0.6	0.6	0.6	0.8	0.6	1.5	0.6	0.8
Illness, injury, bereavement, stress in last 2 years	0.4	0.4	2.9	-0.6	-0.3	1.7	-0.3	-0.3	-0.6	-0.3	-0.7	-0.4	-0.4
Leg fat percentage (left)	0.4	1.3	2.9	-1.3	-1.0	-1.7	-1.1	-1.0	-1.4	-1.1	-1.5	-1.2	-0.6
Commuting to job workplace: Cycle	0.4	0.5	1.1	-0.3	-1.0	0.5	-1.0	-0.9	-0.8	-1.0	-0.0	-1.0	-0.1
Heart disease (siblings)	0.4	0.5	1.1	-0.6	-0.6	-0.7	-0.7	-0.7	-0.9	-0.7	-1.0	-0.8	-0.4
Bipolar Disorder (2011)	0.3	0.2	0.9	-0.8	-0.4	-1.0	-0.3	-0.2	-0.4	-0.4	0.3	-0.4	-0.5
Mean Putamen Volume	0.3	0.3	0.9	0.1	0.4	-0.1	0.5	0.4	1.0	0.4	0.6	0.7	-0.8
HDL Cholesterol	0.3	0.5	2.3	-0.2	-0.6	-1.5	-0.6	-0.6	-0.7	-0.5	0.5	-0.8	-0.2
Rheumatoid Arthritis	0.3	0.4	0.8	-0.1	0.8	-0.3	0.9	0.8	0.7	0.8	-0.2	0.8	-0.2
Number of treatments/medications taken	0.3	0.5	1.1	0.7	0.8	-0.5	0.8	0.7	0.7	0.8	0.4	0.8	1.1
Impedance of leg (right)	0.3	1.6	4.6	0.5	1.3	0.9	1.4	1.5	2.1	1.3	0.5	1.8	-1.2
Taking other prescription medications	0.3	0.5	5.1	-0.2	-0.0	-2.3	-0.0	-0.0	-0.3	-0.0	-0.2	-0.2	0.3
Impedance of leg (left)	0.3	1.6	4.3	0.3	1.3	0.5	1.4	1.5	2.1	1.3	0.5	1.7	-1.3
Had menopause	0.3	0.3	1.5	-1.2	-0.2	-0.8	-0.1	-0.2	-0.5	-0.2	-0.3	-0.3	-1.0
Allergy	0.3	0.8	3.1	0.6	0.7	-0.8	0.8	0.7	1.2	0.7	1.8	0.9	-0.0
Pain all over the body in last month	0.3	0.3	1.3	-0.6	-0.5	0.0	-0.6	-0.5	-0.1	-0.4	-0.7	-0.3	-1.1
Pulse rate	0.3	0.5	0.9	-0.5	-0.6	-1.0	-0.7	-0.7	-0.8	-0.6	-0.9	-0.7	-0.3
Peak expiratory flow (PEF)	0.3	0.7	7.5	0.0	0.1	2.7	0.1	0.4	-0.1	0.1	0.0	0.0	-0.4
High blood pressure (siblings)	0.3	0.4	1.6	-0.4	-0.5	0.6	-0.6	-0.5	-0.8	-0.5	-1.3	-0.6	-0.5
Exposure to tobacco smoke outside home	0.3	0.5	3.0	-0.3	-0.4	-1.7	-0.3	-0.5	-0.3	-0.4	-1.0	-0.4	-0.1
Leg fat mass (right)	0.3	1.2	2.1	-1.3	-1.0	-1.3	-1.0	-1.0	-1.4	-1.1	-1.3	-1.2	-0.6
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.9	0.8	0.6	-0.3	0.7	0.6	0.8	0.6	0.5	0.7	1.0
Mood swings	0.3	0.5	1.7	0.5	0.8	-1.3	0.7	0.9	0.5	0.8	-0.3	0.7	0.1
Medication for cholesterol	0.3	0.4	1.4	0.9	0.4	-0.4	0.5	0.4	0.8	0.5	1.2	0.6	0.6
Arm fat mass (left)	0.3	1.0	2.3	-1.0	-0.8	-1.5	-0.9	-0.9	-1.4	-0.9	-1.4	-1.1	0.1
Irritability	0.3	0.4	1.0	0.4	0.8	1.0	0.7	1.0	0.7	0.7	0.1	0.8	-0.4
Risk taking	0.3	0.4	0.9	-0.4	-0.8	0.0	-0.5	-0.8	-0.9	-0.8	-1.0	-0.8	0.1
Myopia	0.3	0.4	0.7	0.5	0.7	-0.6	0.7	0.7	0.7	0.7	0.5	0.7	0.8
Vascular/heart problems diagnosed by doctor	0.3	0.8	3.4	0.7	0.8	1.8	0.7	0.7	0.8	0.8	1.0	0.8	0.7
Leg fat mass (left)	0.3	1.2	2.2	-1.3	-0.9	-1.5	-1.0	-0.9	-1.5	-1.0	-1.2	-1.2	-0.5
Bipolar Disorder (2018)	0.2	0.4	1.5	-0.2	-0.2	-1.2	-0.4	-0.3	-0.5	-0.3	0.9	-0.5	0.8
Depressed Affect (Nagel 2018)	0.2	0.4	1.7	-0.8	0.1	-1.3	-0.0	0.3	-0.3	0.0	-0.9	0.0	-1.0
Depression (Nagel 2018)	0.2	0.3	0.7	0.4	0.7	-0.4	0.7	0.8	0.6	0.7	0.2	0.7	-0.2
Crohns Disease (2017)	0.2	0.5	2.2	-0.8	-0.6	-1.5	-0.5	-0.6	-0.5	-0.6	0.2	-0.5	-1.1
Ovarian Cancer	0.2	0.2	1.0	0.7	0.2	0.4	0.3	0.2	-0.2	0.3	-0.8	0.1	1.0
Blood Eosinophil Count	0.2	1.4	4.0	0.7	1.3	-2.0	1.4	1.0	1.3	1.2	-0.1	1.3	1.1
Blood Platelet Count	0.2	2.5	6.5	2.0	1.6	0.2	1.6	1.3	1.8	1.6	1.5	1.7	2.5
Hair Pigment	0.2	5.5	8.8	-2.2	-2.6	-2.6	-2.5	-3.0	-2.5	-2.5	-2.6	-2.5	-0.7
Tanning	0.2	2.7	4.8	-1.9	-1.8	0.4	-1.7	-1.6	-1.8	-1.7	-1.5	-1.8	-2.2
Ever had hysterectomy (womb removed)	0.2	0.2	0.6	0.1	-0.5	-0.2	-0.6	-0.6	-0.5	-0.4	-0.7	-0.4	0.8
Medication for hormone replacement therapy	0.2	0.2	0.9	0.1	-0.0	0.8	0.0	-0.2	-0.4	-0.1	-0.6	-0.3	0.9
Age when periods started (menarche)	0.2	0.5	4.5	-0.7	0.2	-2.1	0.2	0.1	0.2	0.3	0.3	0.3	-0.8
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.7	0.8	0.5	0.2	0.4	0.3	0.4	0.4	0.4	0.4	0.8
High blood pressure	0.2	0.6	3.0	-0.5	-0.7	-1.7	-0.6	-0.6	-0.6	-0.7	-0.9	-0.6	-0.5
Forced vital capacity (FVC)	0.2	0.9	2.9	-0.3	0.7	-1.7	0.9	0.7	1.0	0.8	1.3	0.9	-0.8
Financial difficulties in last 2 years	0.2	0.2	0.5	-0.3	-0.6	0.7	-0.4	-0.5	-0.6	-0.5	-0.4	-0.6	0.2
Arm fat percentage (right)	0.2	0.8	3.3	-0.3	-0.6	-1.1	-0.6	-0.6	-1.1	-0.6	-1.8	-0.8	0.8
Hair/balding pattern: Pattern 3	0.2	0.3	1.8	0.4	0.1	1.0	0.1	0.0	-0.0	0.1	0.8	0.0	1.4
Noisy workplace	0.2	0.3	1.0	-0.2	-0.5	0.1	-0.2	-0.4	-0.6	-0.4	-1.0	-0.5	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.8	0.4	-0.2	-0.6	-0.2	-0.3	0.1	-0.2	0.9	-0.1	0.8
Illnesses of mother	0.2	0.2	1.8	-0.5	-0.3	1.3	-0.2	-0.3	-0.2	-0.3	-0.3	-0.2	0.0
Pulse wave Arterial Stiffness index	0.2	0.2	0.5	-0.5	-0.4	-0.7	-0.4	-0.3	-0.4	-0.4	-0.5	-0.4	-0.0
Arm fat mass (right)	0.2	1.0	2.3	-0.9	-0.8	-1.2	-0.8	-0.9	-1.5	-0.9	-1.5	-1.1	0.3
Hair/balding pattern: Pattern 4	0.2	0.6	2.3	0.1	0.6	-1.3	0.6	0.4	0.5	0.6	1.5	0.5	0.7
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.4	-0.2	-0.5	-0.6	-0.5	-0.4	-0.6	-0.5	-0.7	-0.5	-0.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.3	-0.9	-0.5	1.1	-0.5	-0.5	-0.4	-0.5	-0.2	-0.5	-1.0
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.9	0.3	0.5	-1.0	0.5	0.4	0.2	0.3	0.2	0.3	0.3
Forced vital capacity (FVC), Best measure	0.2	0.6	2.4	-0.9	0.3	-1.6	0.5	0.2	0.6	0.3	1.0	0.5	-1.4
Body fat percentage	0.2	0.7	2.6	-0.8	-0.5	-1.4	-0.5	-0.5	-0.9	-0.6	-1.6	-0.7	0.1
Qualifications: College or University degree	0.2	0.7	2.0	-0.5	-0.8	-0.9	-0.9	-0.9	-0.6	-0.9	1.4	-0.8	-0.6
Mouth/teeth dental problems: Loose teeth	0.2	0.3	1.7	-0.6	-0.2	-1.3	-0.4	-0.3	-0.4	-0.3	-0.4	-0.3	-0.5
Medication: Blood pressure	0.2	0.4	0.9	0.9	0.5	-0.7	0.5	0.6	0.5	0.6	0.4	0.5	1.0
Mean time to correctly identify matches	0.2	0.5	2.0	0.6	0.3	-1.4	0.4	0.3	-0.0	0.4	0.3	0.2	1.4
Whole body fat mass	0.2	0.8	2.1	-1.1	-0.6	-1.4	-0.7	-0.6	-1.2	-0.7	-1.4	-0.9	-0.1
Arm predicted mass (right)	0.2	0.9	2.2	-1.5	-0.8	-0.8	-0.9	-0.7	-1.2	-0.9	0.2	-1.1	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.9	0.2	0.4	-1.0	0.7	0.5	0.5	0.5	-0.4	0.5	0.2
Knee pain experienced in last month	0.2	0.3	1.0	-0.5	-0.4	-0.2	-0.5	-0.5	-0.6	-0.5	-1.0	-0.5	-0.3
Arm fat percentage (left)	0.2	0.9	2.6	-0.5	-0.6	-1.4	-0.7	-0.7	-1.2	-0.7	-1.6	-0.9	0.6
Breast cancer (self-reported)	0.2	0.2	0.9	-0.5	-0.3	-0.9	-0.4	-0.3	-0.3	-0.3	0.2	-0.3	-0.9
Average weekly champagne plus white wine intake	0.2	0.2	0.5	-0.4	-0.4	-0.3	-0.6	-0.7	-0.6	-0.5	0.2	-0.6	-0.2
Guilty feelings	0.2	0.4	1.1	-0.6	-0.6	0.2	-0.5	-0.6	-0.8	-0.7	-1.1	-0.7	-0.0
Financial situation satisfaction	0.2	0.2	0.6	0.4	-0.3	0.5	-0.1	-0.2	-0.3	-0.2	-0.8	-0.3	0.8
Tinnitus: Yes, now most or all of the time	0.2	0.3	2.3	0.2	0.1	1.5	0.1	0.0	-0.1	0.1	-0.1	0.0	0.6
Eye problems/disorders: Glaucoma	0.2	0.2	2.0	-0.1	-0.1	1.4	-0.1	-0.0	-0.1	-0.0	0.0	-0.1	0.4
Medication: Paracetamol	0.2	0.3	0.7	-0.4	-0.5	0.4	-0.6	-0.4	-0.5	-0.5	-0.8	-0.5	-0.6
Medication: Atorvastatin	0.2	0.2	0.8	-0.3	-0.2	0.7	-0.3	-0.0	-0.4	-0.2	-0.9	-0.3	-0.8
Diastolic blood pressure, automated reading	0.2	0.5	3.3	0.2	-0.3	1.8	-0.4	-0.2	-0.7	-0.4	-1.0	-0.5	0.2
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.7	-0.5	-0.4	-0.3	-0.4	-0.2	-0.1	-0.4	-0.9	-0.2	-0.7
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.5	0.1	0.6	0.4	0.7	0.6	0.3	0.6	0.0	0.5	0.1
Alcohol drinker status: Previous	0.2	0.2	0.4	0.5	0.4	-0.5	0.3	0.3	0.4	0.4	0.6	0.4	0.5
Arm predicted mass (left)	0.2	0.8	2.1	-1.4	-0.8	-0.9	-0.8	-0.7	-1.1	-0.9	-0.1	-1.0	-1.0
Neuroticism (Nagel 2018)	0.1	0.4	0.8	0.0	0.6	-0.3	0.8	0.9	0.6	0.6	-0.8	0.7	-0.5
Alzheimer’s Disease (in mother)	0.1	0.1	0.4	-0.2	-0.3	-0.1	-0.3	-0.4	-0.7	-0.3	0.0	-0.5	0.2
Irritable Bowel Disease (IBD)	0.1	0.3	0.5	-0.4	-0.7	-0.2	-0.5	-0.6	-0.4	-0.7	0.4	-0.6	-0.6
Ulcerative Colitis (UC)	0.1	0.2	0.7	-0.0	-0.6	0.8	-0.4	-0.5	-0.1	-0.6	0.5	-0.4	-0.0
Crohns Disease (2012)	0.1	0.2	1.1	-0.3	0.3	-1.1	0.4	0.4	0.4	0.3	0.5	0.3	-0.3
Lupus	0.1	0.1	0.6	-0.3	-0.1	-0.8	-0.1	-0.1	0.1	-0.0	0.4	0.0	-0.5
Ulcerative Colitis	0.1	0.2	0.5	0.5	0.1	0.4	0.3	0.2	0.7	0.2	0.5	0.4	0.6
Blood Red Count	0.1	0.8	5.2	1.3	0.5	0.8	0.6	0.5	-0.3	0.4	-0.4	0.0	2.3
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.3	-0.5	-0.1	0.5	-0.1	-0.2	-0.3	-0.2	-0.5	-0.2	-0.0
Supplements: Zinc	0.1	0.1	0.3	0.3	-0.3	-0.1	-0.1	-0.3	-0.0	-0.3	0.3	-0.2	0.5
Diabetes (father)	0.1	0.2	0.5	0.0	-0.3	0.6	-0.3	-0.3	-0.5	-0.3	-0.7	-0.4	0.4
Severe depression (siblings)	0.1	0.1	0.3	0.2	0.4	0.4	0.3	0.4	0.4	0.4	0.5	0.4	0.1
Trunk fat percentage	0.1	0.4	2.1	-0.4	0.0	-1.3	-0.0	-0.0	-0.5	-0.1	-1.4	-0.2	0.4
Hand grip strength (right)	0.1	0.2	1.6	0.3	0.0	1.3	-0.0	0.1	-0.3	-0.0	-0.0	-0.1	-0.4
Maternal smoking around birth	0.1	0.2	1.4	0.0	0.3	1.2	0.4	0.3	0.1	0.3	-0.4	0.3	-0.3
Fed-up feelings	0.1	0.3	1.4	-0.4	0.1	-0.8	-0.1	0.2	-0.4	0.0	-1.2	-0.1	-0.7
Relative age voice broke	0.1	0.2	0.4	0.5	0.5	0.5	0.4	0.5	0.4	0.6	-0.3	0.5	0.7
Multivitamins +/- minerals	0.1	0.2	0.8	0.1	-0.2	0.8	-0.2	-0.3	-0.2	-0.1	0.1	-0.2	0.9
Medication: Atenolol	0.1	0.2	1.1	0.5	-0.1	1.1	0.0	-0.0	0.1	-0.0	0.1	-0.0	0.6
Trunk fat mass	0.1	0.3	1.6	-0.5	0.0	-1.3	0.0	0.0	-0.5	-0.1	-1.0	-0.2	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.4	0.5	0.6	-0.6	0.5	0.6	0.5	0.6	0.2	0.6	-0.2
Heart attack	0.1	0.1	0.3	-0.1	0.4	0.2	0.6	0.5	0.2	0.4	-0.0	0.3	-0.1
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.5	0.6	0.5	0.3	0.7	0.6	0.2	0.5	-0.1	0.4	0.2
Weight	0.1	0.2	1.0	-0.7	-0.2	-1.0	-0.2	-0.1	-0.8	-0.3	-0.4	-0.5	0.1
Hip circumference	0.1	0.5	2.8	0.1	0.7	-1.7	0.6	0.6	0.1	0.5	0.6	0.3	0.6
Time employed in main current job	0.1	0.1	0.6	0.3	0.1	0.8	0.1	0.1	0.2	0.2	0.3	0.2	0.8
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	0.9	-0.1	0.6	-0.5	0.7	0.6	0.7	0.6	1.0	0.7	-0.5
Happiness	0.1	0.1	0.4	0.2	0.4	0.6	0.3	0.4	0.4	0.4	-0.2	0.4	-0.1
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.0	-0.4	-0.3	-0.5	-0.3	-0.3	-0.2	-0.4	1.0	-0.3	-0.4
Asthma	0.1	0.3	1.1	-0.3	-0.4	0.5	-0.3	-0.4	-0.8	-0.4	-1.0	-0.5	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.9	-0.6	0.3	-0.1	0.4	0.2	0.4	0.3	0.8	0.4	-1.0
Length of working week for main job	0.1	0.1	1.1	-0.1	-0.2	-1.1	-0.3	-0.2	-0.3	-0.2	-0.3	-0.3	-0.2
Birth weight of first child	0.1	0.2	0.9	0.0	0.3	-1.0	0.4	0.2	0.8	0.3	0.1	0.6	-0.3
Glaucoma (self-reported)	0.1	0.2	0.5	-0.5	-0.4	0.7	-0.5	-0.4	-0.4	-0.4	-0.3	-0.4	-0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.9	0.4	0.1	0.6	0.1	0.1	-0.4	0.1	-1.0	-0.1	0.6
Arm fat-free mass (right)	0.1	0.6	1.9	-1.4	-0.6	-1.0	-0.6	-0.5	-1.0	-0.7	0.4	-0.8	-1.0
Migraine (self-reported)	0.1	0.2	0.6	0.1	-0.4	0.7	-0.4	-0.5	-0.4	-0.4	0.0	-0.4	0.0
Leg pain on walking	0.1	0.1	0.5	-0.1	0.3	-0.4	0.2	0.3	0.2	0.3	-0.7	0.3	-0.1
Hypertension (Self-reported)	0.1	0.3	2.1	-0.2	-0.4	-1.4	-0.4	-0.4	-0.4	-0.5	-0.4	-0.4	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.5	0.3	-0.1	0.6	-0.1	0.0	-0.1	-0.2	-0.5	-0.1	0.7
Loneliness, isolation	0.1	0.1	0.9	0.1	0.2	0.9	0.3	0.5	-0.1	0.2	-0.4	0.1	0.1
Qualifications: nursing, teaching	0.1	0.2	2.2	0.2	-0.1	-0.2	-0.1	-0.1	-0.1	-0.2	1.5	-0.2	0.4
Commuting to job workplace: Walk	0.1	0.1	0.5	-0.0	-0.1	-0.2	-0.1	-0.1	0.0	-0.1	-0.3	-0.0	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.3	-0.0	0.4	-0.5	0.5	0.4	0.2	0.4	0.2	0.3	0.3
Asthma (self-reported)	0.1	0.3	1.0	-0.2	-0.4	0.4	-0.3	-0.5	-0.8	-0.4	-1.0	-0.6	0.3
Illnesses of father: None of the above (group 1)	0.1	0.1	0.5	0.2	0.3	-0.7	0.3	0.2	0.2	0.3	0.6	0.2	0.4
Miserableness	0.1	0.2	0.5	0.0	0.5	-0.7	0.3	0.6	0.1	0.4	-0.5	0.3	-0.5
Mother’s age at death	0.1	0.1	0.7	0.1	-0.3	-0.1	-0.3	-0.4	-0.4	-0.3	0.2	-0.3	0.8
Medication: Blood pressure	0.1	0.2	1.3	-0.7	-0.3	-1.1	-0.1	-0.2	-0.4	-0.3	-0.5	-0.3	-0.2
Illnesses of father: High blood pressure	0.1	0.1	0.4	0.2	-0.1	-0.2	-0.2	-0.2	0.1	-0.2	-0.7	-0.0	-0.1
Arm fat-free mass (left)	0.1	0.5	1.6	-1.3	-0.5	-0.9	-0.6	-0.5	-1.0	-0.7	0.0	-0.8	-0.9
Age started oral contraceptive pill	0.1	0.2	0.5	-0.1	0.6	0.3	0.7	0.5	0.2	0.6	-0.1	0.4	0.3
Alzheimer’s Disease (in father)	0.0	0.1	0.3	-0.2	-0.0	0.5	0.0	0.1	-0.1	-0.0	-0.5	-0.1	-0.1
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cardiovascular Disease	0.0	0.0	0.1	0.3	-0.1	-0.2	-0.1	0.0	-0.0	-0.1	0.3	-0.1	0.3
Vitamin and mineral supplements	0.0	0.0	0.3	-0.1	0.0	0.1	0.0	0.1	0.2	0.0	0.0	0.1	-0.6
Leg fat-free mass (left)	0.0	0.1	0.6	-0.0	0.1	-0.6	0.1	0.1	-0.4	0.0	0.2	-0.2	0.8
Sitting height	0.0	0.3	2.0	-0.8	0.1	1.4	0.1	0.2	0.1	0.1	0.2	0.1	-0.8
Leg predicted mass (left)	0.0	0.1	0.8	-0.0	0.2	-0.6	0.1	0.2	-0.4	0.1	0.2	-0.2	0.9
Trunk fat-free mass	0.0	0.1	1.0	-0.4	0.2	0.0	0.1	0.3	-0.2	0.1	1.0	-0.1	-0.1
Trunk predicted mass	0.0	0.1	1.0	-0.4	0.1	-0.0	0.1	0.2	-0.2	0.1	1.0	-0.1	-0.1
Suffer from ‘nerves’	0.0	0.1	0.2	-0.4	0.2	-0.2	0.2	0.2	0.3	0.2	-0.2	0.2	-0.4
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.1	-0.3	-0.1	-0.3	0.1	-0.0	-0.3	-0.0	-0.4	-0.1	0.3
Medication: Aspirin	0.0	0.1	0.3	-0.5	-0.2	0.0	-0.1	-0.1	-0.4	-0.2	-0.2	-0.3	-0.2
Illnesses of father: Heart disease	0.0	0.0	0.2	-0.2	0.1	0.4	0.1	0.0	0.1	0.1	0.0	0.1	-0.4
Whole body fat-free mass	0.0	0.1	0.3	-0.4	0.0	-0.4	-0.0	0.1	-0.5	-0.1	0.5	-0.3	0.1
Leg fat-free mass (right)	0.0	0.1	0.8	0.0	0.2	-0.6	0.2	0.2	-0.4	0.1	0.3	-0.1	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.1	0.1	-0.1	-0.3	0.2	-0.4	-0.3	-0.3	-0.2	0.0	-0.3	0.2
Eye problems/disorders: Cataract	0.0	0.0	0.2	-0.3	-0.0	0.3	-0.0	0.1	-0.2	-0.1	-0.3	-0.2	-0.4
Medication: Aspirin	0.0	0.0	0.1	-0.4	-0.1	0.4	-0.0	0.0	-0.3	-0.0	-0.2	-0.1	-0.1
Whole body water mass	0.0	0.1	0.4	-0.4	0.0	-0.4	-0.0	0.1	-0.5	-0.1	0.6	-0.3	0.1
Leg predicted mass (right)	0.0	0.1	0.9	0.0	0.2	-0.6	0.2	0.2	-0.4	0.1	0.3	-0.1	0.9
Basal metabolic rate	0.0	0.1	0.2	-0.4	0.1	-0.5	0.0	0.1	-0.4	-0.0	0.4	-0.2	0.2

Hub : Genes

TRIAP1

Models

Trait associations