Best TWAS P=5.02e-08 · Best GWAS P=4.28e-09 conditioned to 0.00108
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | CYB561 | 0.07 | 0.04 | enet | 21 | 0.06 | 4.7e-04 | 4.9 | -5.3 | 1.2e-07 | -0.62 | 0.10 | 0.42 | FALSE |
2 | GTEx | Brain Nucleus accumbens basal ganglia | CYB561 | 0.42 | 0.39 | enet | 28 | 0.36 | 1.9e-10 | 4.9 | -5.3 | 1.2e-07 | -0.67 | 0.39 | 0.61 | FALSE |
3 | GTEx | Brain Putamen basal ganglia | CYB561 | 0.30 | 0.28 | enet | 21 | 0.27 | 4.1e-07 | 4.8 | -5.5 | 5.0e-08 | -0.60 | 0.34 | 0.62 | TRUE |
4 | GTEx | Colon Transverse | TANC2 | 0.11 | 0.05 | enet | 20 | 0.06 | 1.1e-03 | 5.9 | -5.2 | 2.2e-07 | -0.75 | 0.02 | 0.86 | FALSE |
5 | GTEx | Muscle Skeletal | TANC2 | 0.08 | 0.05 | lasso | 3 | 0.02 | 3.7e-03 | 5.2 | 5.2 | 2.2e-07 | 0.89 | 0.02 | 0.97 | FALSE |