[Hub]/) : Traits : Neuroticism : ← →

chr3:48,702,606-51,043,528

Best TWAS P=1.7e-09 · Best GWAS P=4.11e-07 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Brain Frontal Cortex BA9	GPX1	0.16	0.06	lasso	6	0.15	7.9e-05	4.1	6.0	1.7e-09	-0.01	0.05	0.61	TRUE
8	GTEx	Nerve Tibial	U73166.2	0.07	0.03	lasso	3	0.03	2.8e-03	5.0	-5.1	2.9e-07	-0.96	0.01	0.97	TRUE
6	GTEx	Lung	GPX1	0.04	0.02	enet	13	0.04	5.7e-04	-4.0	5.6	1.6e-08	0.00	0.06	0.39	FALSE
5	GTEx	Esophagus Muscularis	GPX1	0.13	0.05	lasso	14	0.06	1.1e-04	-4.2	5.5	3.3e-08	-0.04	0.10	0.75	FALSE
2	GTEx	Brain Caudate basal ganglia	RBM6	0.20	0.14	enet	16	0.11	5.5e-04	-4.3	-5.5	3.8e-08	-0.29	0.36	0.36	FALSE
3	GTEx	Brain Cerebellum	GPX1	0.31	0.09	enet	19	0.23	2.0e-07	-4.2	5.5	4.5e-08	-0.04	0.10	0.74	FALSE
1	GTEx	Adipose Subcutaneous	TCTA	0.05	0.01	enet	10	0.01	5.8e-02	4.3	-5.2	2.1e-07	0.07	0.06	0.39	FALSE
7	GTEx	Nerve Tibial	HYAL1	0.08	0.06	enet	14	0.05	3.6e-04	3.6	5.2	2.5e-07	0.60	0.06	0.78	FALSE