Hub : Genes

HYAL1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.0950 0.0510 5.3e-03 0.058 NA 0.049 NA 0.052 1.5e-05 NA 6.6e-05 NA 4.3e-05
2 GTEx Esophagus Gastroesophageal Junction 0.2950 0.1020 2.5e-03 0.134 NA 0.068 NA 0.098 1.5e-05 NA 1.8e-03 NA 2.1e-04
3 GTEx Esophagus Muscularis 0.1050 0.0470 7.0e-04 0.077 NA 0.027 NA 0.054 1.9e-05 NA 8.8e-03 NA 3.3e-04
4 GTEx Heart Atrial Appendage 0.2320 0.0830 3.4e-04 0.097 NA 0.133 NA 0.104 4.2e-05 NA 1.5e-06 NA 2.2e-05
5 GTEx Heart Left Ventricle 0.2294 0.0741 1.9e-05 0.032 NA 0.121 NA 0.081 8.2e-03 NA 5.8e-07 NA 4.4e-05
6 GTEx Muscle Skeletal 0.0838 0.0376 8.6e-04 0.075 NA 0.048 NA 0.064 7.5e-08 NA 1.6e-05 NA 7.6e-07
7 GTEx Nerve Tibial 0.0797 0.0458 1.4e-03 0.056 NA 0.045 NA 0.043 8.5e-05 NA 3.6e-04 NA 4.9e-04
8 GTEx Skin Sun Exposed Lower leg 0.0830 0.0440 5.7e-03 0.037 NA 0.029 NA 0.039 5.0e-04 NA 1.6e-03 NA 3.5e-04
9 METSIM Adipose 0.0668 0.0265 1.1e-04 0.036 0.028 0.031 0.026 0.028 3.2e-06 3.6e-05 1.5e-05 6.8e-05 4.4e-05
10 ROSMAP Brain Pre-frontal Cortex 0.1019 0.0429 9.5e-06 0.041 0.037 0.013 0.037 0.022 5.1e-06 1.3e-05 8.1e-03 1.4e-05 7.4e-04
11 TCGA Brain Lower Grade Glioma 0.1015 0.0639 2.5e-06 0.056 0.052 0.050 NA 0.053 5.1e-07 1.4e-06 2.2e-06 NA 1.2e-06
12 TCGA Prostate Adenocarcinoma 0.0431 0.0243 7.2e-04 0.003 0.012 0.004 NA 0.005 1.4e-01 1.8e-02 1.2e-01 NA 7.8e-02
13 TCGA Skin Cutaneous Melanoma 0.2630 0.1300 9.2e-03 0.018 0.008 0.008 NA 0.043 1.1e-01 1.9e-01 1.9e-01 NA 2.6e-02
14 TCGA Thyroid Carcinoma 0.0830 0.0510 4.8e-04 -0.001 0.035 0.043 NA 0.036 4.6e-01 2.2e-04 4.6e-05 NA 1.7e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 1.3 2.1 8.4 1.4 1.4 1.3 2.2 -0.6 1.0 2.9 -0.8 1.6 0.9 0.0 -1.0 -0.6 -1.9
Bipolar Disorder or Schizophrenia 0.6 1.3 4.4 1.0 0.9 0.9 1.9 -0.8 1.0 1.5 -1.5 0.8 0.4 0.0 -0.8 -0.7 -2.1
Depressed Affect (Nagel 2018) 2.9 6.0 24.7 2.7 2.8 2.9 1.6 -0.2 3.0 5.0 -2.6 2.4 0.7 2.7 2.1 0.7 -0.3
Depression (Nagel 2018) 9.5 14.2 20.4 4.4 4.5 4.5 4.2 2.6 4.5 3.9 -4.2 4.1 3.4 4.3 3.3 0.8 1.6
Intelligence (Savage-Jansen 2018) 1.2 3.6 40.6 -0.6 -0.8 -0.7 -0.7 0.5 -0.7 -6.4 0.7 -0.2 -0.0 -0.9 1.1 1.6 1.4
Neuroticism (Nagel 2018) 7.8 18.3 30.0 5.1 5.2 5.3 3.4 2.2 5.5 4.9 -4.9 4.7 3.0 5.1 4.4 1.5 1.5
Schizophrenia (2018) 0.1 0.3 1.4 0.1 -0.0 0.2 0.7 -0.6 0.4 -0.5 -1.1 -0.1 -0.2 0.0 -0.3 -0.5 -1.2
Schizophrenia vs Biploar Disorder 1.3 1.7 14.4 -0.9 -1.2 -1.1 -1.4 -0.4 -1.1 -3.8 -0.0 -1.3 -0.4 0.0 -0.3 -0.2 -0.0
Worry (Nagel 2018) 13.3 28.1 41.0 6.1 6.2 6.3 5.0 4.8 6.4 4.4 -5.8 6.0 5.0 6.2 5.0 1.1 3.0
Alzheimer’s Disease (in mother) 0.4 0.5 2.6 0.2 0.4 0.1 0.8 0.6 -0.2 1.1 0.1 0.6 0.4 -0.3 -1.0 -0.7 -1.6
Alzheimer’s Disease (in father) 0.0 0.0 0.3 -0.2 -0.1 -0.1 0.1 0.1 0.1 0.3 0.0 0.3 0.6 0.0 -0.0 0.2 -0.2
Alzheimer’s Disease (including proxy) 0.2 0.4 1.4 0.0 0.1 0.0 0.7 0.1 -0.1 1.0 0.2 0.6 0.7 -0.2 -0.9 -0.6 -1.2
Crohns Disease (2017) 2.3 5.1 16.5 -2.1 -2.1 -2.2 -2.0 -2.6 -2.3 -4.1 2.0 -1.9 -1.9 -2.7 -1.6 -0.7 -1.8
Irritable Bowel Disease (IBD) 1.5 3.6 25.9 -1.7 -1.6 -1.7 -1.4 -0.5 -1.8 -5.1 1.9 -1.1 -0.3 -2.2 -0.4 0.7 0.1
Ulcerative Colitis (UC) 1.2 2.2 20.2 -1.0 -0.9 -0.9 -0.7 1.3 -0.9 -4.5 1.2 -0.1 0.5 -1.1 0.2 0.8 1.3
Major Depression (MDD) 0.1 0.2 1.8 0.0 0.0 1.4 0.4 -0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0
Reaction Time 0.7 1.4 7.5 -0.5 -0.4 -0.6 -1.7 -1.9 -0.8 -1.4 0.3 -0.6 -2.7 -1.1 -0.1 0.2 -0.7
Verbal and Numeric Reasoning (VNR) 1.6 3.9 28.0 -1.6 -1.8 -1.7 -2.1 -0.4 -1.7 -5.3 1.6 -1.3 -1.1 -1.8 0.0 1.3 0.6
Breast Cancer 2.2 5.4 11.0 -2.4 -2.3 -2.4 -2.7 -2.5 -2.4 -3.3 2.5 -2.2 -2.0 -2.4 -2.1 -1.0 -1.4
Ovarian Cancer 0.1 0.2 0.8 -0.2 -0.2 -0.3 -0.5 -0.2 -0.3 -0.5 0.4 -0.5 -0.7 -0.2 0.2 0.1 0.9
Prostate Cancer 2.3 3.2 8.8 1.9 1.9 1.9 2.2 1.2 1.8 3.0 -1.6 1.7 0.9 1.9 1.6 1.1 1.3
Age at First Birth 2.4 3.5 23.6 -0.2 -0.1 0.0 1.3 3.0 0.3 -4.9 -0.6 0.4 2.5 0.0 1.2 0.0 2.4
Bipolar Disorder (2011) 0.2 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 -1.6 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 1.4 1.9 6.5 -1.2 -1.1 -1.1 -1.3 -2.5 -1.1 1.5 1.0 -0.8 -2.1 0.0 -1.4 0.0 -1.7
Coronary Artery Disease (CAD) 0.8 0.9 2.0 -0.9 -0.9 -0.9 -1.4 -1.4 -0.9 1.4 0.8 -1.2 -1.3 0.0 0.0 0.0 0.0
Crohns Disease (2012) 1.5 2.5 12.5 -1.4 -1.5 -1.5 -1.2 -1.0 -1.7 -3.5 1.6 -1.1 -1.1 0.0 -1.9 -0.9 -0.7
Mean Putamen Volume 3.7 4.3 8.5 2.6 2.4 2.5 2.9 1.4 2.5 1.2 -2.4 2.1 1.9 2.5 0.8 -1.5 0.1
Fasting Glucose 1.0 1.2 6.6 0.5 0.3 0.4 -0.2 0.5 0.5 -0.2 -0.7 -0.1 0.4 0.0 2.0 1.9 2.6
HbA1C 1.1 1.2 6.3 -1.0 -1.0 -1.0 -0.4 2.5 -1.1 -1.1 1.0 -0.5 1.6 0.0 0.3 0.0 1.3
HDL Cholesterol 1.1 1.9 9.7 -1.0 -1.2 -1.2 -1.8 -1.0 -1.1 -3.1 1.0 -1.4 -1.3 0.0 -1.4 0.0 -0.5
LDL Cholesterol 1.1 1.8 3.9 -1.4 -1.6 -1.5 -1.7 -2.0 -1.5 -1.4 1.3 -1.9 -1.3 0.0 -0.7 0.0 -0.3
Lupus 1.5 2.2 10.0 -1.3 -1.2 -1.2 0.9 -0.8 -1.1 1.2 0.3 -1.0 0.2 -0.9 -2.8 -1.7 -3.2
Neuroticism (2016) 6.4 9.3 16.6 3.6 3.8 3.8 2.3 1.8 3.6 3.1 -4.1 3.1 2.7 3.5 3.3 0.0 1.2
Primary Biliary Cirrhosis 0.2 0.3 1.4 -0.2 -0.4 -0.2 0.5 0.1 0.1 -0.8 -0.1 -0.3 0.5 0.3 0.5 0.8 1.2
Rheumatoid Arthritis 0.3 0.4 1.0 0.7 0.7 0.7 0.4 0.5 0.6 -0.1 -0.6 1.0 0.1 0.6 0.2 -0.7 0.6
Schizophrenia (2014) 0.2 0.4 2.3 0.1 0.1 0.2 0.9 -0.8 0.3 -0.2 -0.8 0.0 -0.3 0.0 -0.5 0.0 -1.5
Triglycerides 0.3 0.5 0.9 -0.9 -0.9 -0.9 0.0 0.4 -0.9 -0.6 0.8 -0.9 1.0 0.0 -0.6 0.0 -0.4
Type 2 Diabetes (T2D) (2012) 0.2 0.3 1.0 -0.7 -0.6 -0.7 -0.5 0.6 -0.7 0.1 0.1 -0.3 1.0 0.0 0.0 0.0 -0.3
Ulcerative Colitis 1.6 2.3 16.3 -1.3 -1.2 -1.2 -1.9 0.1 -1.2 -4.0 1.6 -0.5 -0.7 0.0 -0.2 0.8 1.3
Blood Eosinophil Count 1.5 11.2 40.9 2.1 2.2 2.2 6.4 3.8 2.1 5.9 -2.2 2.3 5.7 2.1 -0.4 -0.5 -1.4
Blood Platelet Count 2.2 25.4 38.4 -5.9 -5.7 -5.9 -5.6 -5.3 -6.0 -1.8 6.1 -5.3 -6.0 -6.2 -3.2 0.5 -2.3
Blood Red Count 1.6 15.3 58.8 3.2 3.7 3.6 3.8 7.7 3.5 2.0 -3.1 3.2 6.4 3.8 2.3 0.0 2.7
Blood White Count 0.3 2.6 23.0 -0.6 -0.1 -0.3 -0.2 1.0 -0.5 4.8 0.5 -0.8 0.8 -0.4 1.1 2.6 1.3
Heel T-Score 0.5 4.2 20.8 0.9 1.4 1.4 -0.1 3.2 1.4 2.6 -1.2 0.7 4.6 1.9 1.4 1.1 2.4
BMI 2.7 15.6 40.8 -3.5 -3.1 -3.2 -4.3 -5.8 -3.2 6.4 2.5 -3.1 -5.2 -3.6 -2.2 0.4 -4.7
Height 1.9 35.8 166.4 4.9 4.5 4.6 9.2 9.6 4.4 2.6 -3.7 4.3 12.9 4.5 2.1 -0.9 2.8
Waist Hip Ratio (WHR) 6.1 27.6 49.4 5.5 5.6 5.7 6.1 7.0 5.8 3.6 -4.8 5.8 6.9 5.8 3.6 0.5 2.7
Systolic Blood Pressure 0.2 0.8 4.2 -0.5 -0.3 -0.3 0.1 1.9 -0.1 0.7 0.2 -0.4 2.0 0.2 -0.9 -0.0 -1.2
Smoking Status 3.9 9.4 26.5 -3.1 -3.0 -3.0 -2.3 -5.2 -3.0 1.4 3.2 -2.8 -4.5 -3.4 -1.6 1.1 -2.9
Allergy or Eczema 0.9 2.3 6.5 1.4 1.4 1.5 2.6 1.1 1.8 0.2 -1.6 1.2 2.2 2.0 0.8 -0.6 1.3
Cardiovascular Disease 0.2 0.6 2.4 -1.2 -0.8 -0.8 -1.6 0.4 -0.6 0.3 0.6 -0.9 0.3 -0.6 -0.1 0.7 -0.5
Hypothyroidism (self reported) 0.1 0.3 1.0 -0.0 0.4 0.3 -0.2 -0.1 0.4 1.0 -0.5 -0.1 -0.7 0.4 -0.4 -0.9 -0.9
Respiratory disease 1.6 3.5 15.7 1.3 1.4 1.4 2.4 0.4 1.6 4.0 -1.3 1.9 0.6 1.3 -0.8 -2.3 -2.4
Type 2 Diabetes (T2D) (2018) 0.8 1.4 10.6 0.5 0.7 0.7 1.0 0.7 0.6 3.2 -0.8 0.9 1.2 0.6 0.1 0.9 -1.5
Lung FEV1/FVC ratio 0.9 4.5 12.2 1.8 1.8 1.7 2.9 2.4 1.6 1.3 -2.3 1.5 2.8 1.6 2.1 3.5 1.2
Lung FVC 2.8 14.3 25.8 -3.8 -4.1 -4.2 -4.0 -2.3 -4.2 -4.5 3.8 -3.1 -5.1 -4.4 -3.5 -1.3 -3.2
Neuroticism 6.6 15.8 26.6 4.6 4.7 4.8 3.1 2.2 5.0 5.2 -4.9 4.4 3.0 4.6 3.9 1.2 0.8
Chronotype (morning person) 9.3 21.4 45.2 -5.3 -5.5 -5.3 -6.7 -3.4 -5.1 -6.5 5.0 -4.6 -3.3 -5.0 -1.8 1.1 1.0
Hair Pigment 0.1 3.3 14.1 -1.4 -1.3 -1.3 -0.6 -1.6 -1.4 0.7 1.1 -1.2 -1.4 -1.6 -2.8 -2.6 -3.8
Tanning 0.2 1.8 5.1 -1.8 -1.6 -1.5 -1.9 -2.3 -1.1 0.6 1.0 -1.7 -1.4 -1.0 -0.8 -0.1 -0.4
Hand grip strength (left) 1.0 2.7 4.8 -2.1 -2.1 -2.2 -1.6 -0.7 -2.2 -0.0 2.1 -2.2 0.5 -2.0 -1.7 -0.4 -0.3
Number of treatments/medications taken 1.5 2.8 22.7 1.0 1.3 1.3 1.0 1.2 1.6 4.8 -1.3 1.4 0.5 1.4 1.0 0.4 -0.4
Average weekly spirits intake 3.0 3.7 6.5 2.6 2.4 2.3 1.7 0.9 2.2 2.5 -2.2 1.7 1.8 2.3 1.3 -0.4 1.1
Sensitivity / hurt feelings 3.1 5.4 8.2 2.8 2.9 2.9 1.9 1.1 2.8 2.2 -2.8 2.5 2.0 2.4 2.7 1.5 0.7
Frequency of depressed mood in last 2 weeks 12.4 17.4 24.5 4.9 4.9 5.0 4.4 2.5 4.9 4.7 -4.8 4.5 3.0 4.7 4.1 1.6 2.1
Hearing difficulty/problems: Yes 0.2 0.4 1.9 0.5 0.4 0.5 -0.0 -0.6 0.8 0.2 -0.3 0.5 -0.2 0.5 1.4 0.8 0.1
Relative age of first facial hair 2.7 5.5 18.9 2.1 2.1 2.1 3.8 -0.7 2.1 4.3 -1.8 1.8 3.2 1.9 0.1 -0.1 -2.3
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 2.8 1.5 1.3 1.4 0.9 1.3 1.4 0.4 -1.0 1.7 -0.0 1.3 0.3 -1.0 -0.4
Ever used hormone-replacement therapy (HRT) 0.5 0.6 2.7 -0.8 -0.7 -0.6 0.0 -0.9 -0.5 1.6 0.7 -0.4 -1.0 -0.3 -1.1 0.0 -0.4
Ever had hysterectomy (womb removed) 1.1 1.2 6.0 0.4 0.5 0.5 1.0 -1.3 0.5 2.5 -0.6 0.1 -1.2 0.5 -1.1 -1.3 -1.6
Systolic blood pressure, automated reading 0.9 2.6 4.8 -2.1 -2.0 -2.0 -2.1 -0.8 -1.7 -0.1 1.7 -2.2 -0.9 -1.6 -1.4 0.6 -1.4
Eye problems/disorders: Diabetes related eye disease 3.4 3.7 6.5 1.9 2.2 2.1 2.0 2.3 2.0 1.1 -1.5 2.5 2.2 1.7 2.3 1.3 1.3
Angina 0.5 0.7 3.3 0.3 0.3 0.3 -0.3 0.1 0.5 0.4 -0.0 0.5 0.0 0.5 1.6 1.5 1.8
Medication for hormone replacement therapy 1.2 1.3 4.3 -1.2 -0.9 -0.9 0.1 -0.5 -0.7 1.4 0.6 -1.2 -0.6 -0.5 -2.1 -1.6 -1.7
Vitamin and mineral supplements 1.1 1.5 4.7 -1.3 -1.2 -1.3 -2.2 -1.0 -1.4 -0.3 1.4 -1.1 -1.4 -1.4 -0.2 1.2 0.0
Supplements: Zinc 0.8 0.8 4.4 -0.8 -0.7 -0.7 -0.4 -0.3 -0.5 -0.8 0.4 -0.1 -0.6 -0.5 -1.5 -2.1 -1.0
Medication: Co-codamol 1.2 1.4 9.5 -0.1 -0.1 -0.0 -0.7 -1.9 0.0 3.1 -0.0 -0.4 -2.0 -0.1 -0.5 -0.3 -1.4
Medication: Metformin 0.4 0.6 1.3 -1.0 -0.8 -0.8 -0.6 -0.2 -0.8 0.9 0.7 -0.5 0.5 -0.9 -0.2 1.1 -0.9
Diabetes (father) 1.4 1.7 4.2 1.0 1.2 1.2 1.6 1.5 1.2 2.0 -1.0 1.8 1.2 1.2 1.1 1.2 0.2
Diabetes (mother) 0.5 0.6 2.3 0.5 0.6 0.7 0.7 0.6 0.8 1.0 -0.8 0.4 1.5 0.7 1.0 0.8 0.4
Severe depression (siblings) 5.7 6.4 10.5 3.0 3.0 3.0 3.2 1.6 2.9 1.9 -3.0 2.9 2.9 2.8 0.6 -1.6 -0.9
Pack years adult smoking proportion 4.8 7.3 19.1 -2.9 -2.7 -2.8 -3.5 -2.4 -3.0 -0.8 2.6 -2.5 -4.4 -3.4 -1.5 -0.5 -2.1
Impedance of leg (right) 11.4 55.0 104.0 7.9 8.0 8.0 8.4 9.0 8.0 -0.4 -7.2 6.7 10.2 8.5 6.3 1.1 7.1
Leg fat-free mass (left) 1.7 9.1 19.3 -3.0 -2.8 -2.9 -2.4 -3.1 -2.9 4.3 2.7 -2.6 -2.4 -3.2 -2.9 -0.8 -4.4
Trunk fat percentage 0.8 3.3 23.2 1.5 1.8 1.8 0.9 0.6 1.7 4.8 -1.7 1.0 1.3 1.6 1.5 0.5 -0.0
Hand grip strength (right) 1.0 2.8 5.3 -2.0 -2.0 -2.0 -1.1 -0.6 -2.0 1.4 1.9 -2.2 0.8 -1.7 -2.3 -0.8 -1.1
Townsend deprivation index at recruitment 1.2 1.7 5.0 -1.0 -1.1 -1.1 -2.0 -1.7 -1.2 0.3 0.9 -1.6 -2.2 -1.2 0.4 1.3 -0.2
Current tobacco smoking 0.7 1.2 4.5 -0.6 -0.5 -0.7 -0.7 -1.5 -0.8 1.9 0.9 -0.7 -2.1 -1.0 0.1 1.1 -0.4
Average weekly fortified wine intake 0.3 0.4 1.2 -0.6 -0.6 -0.5 -0.4 -0.1 -0.3 0.7 0.4 -0.6 -0.3 -0.2 -1.1 -1.1 -0.6
Maternal smoking around birth 4.2 6.0 12.0 -3.0 -2.6 -2.7 -2.1 -2.2 -2.7 1.3 2.3 -1.9 -2.6 -2.8 -2.7 -0.3 -3.5
Fed-up feelings 2.8 5.2 21.9 2.2 2.3 2.4 0.9 0.0 2.4 4.7 -2.3 1.7 0.7 2.2 3.0 1.9 1.4
Frequency of unenthusiasm / disinterest in last 2 weeks 8.2 10.9 18.8 4.0 4.0 4.0 3.0 1.7 4.0 4.3 -3.7 3.4 2.7 3.8 3.0 0.8 0.8
Relative age voice broke 0.7 1.0 4.0 0.5 0.5 0.6 2.0 -1.0 0.6 1.8 -0.6 0.4 1.5 0.5 0.6 1.0 -0.6
Taking other prescription medications 4.5 6.9 34.7 2.3 2.6 2.7 2.7 1.4 2.8 5.9 -2.4 2.3 2.0 2.6 1.8 0.9 -0.4
Age when periods started (menarche) 1.1 2.7 22.6 0.1 0.1 0.2 2.6 -1.2 0.4 4.8 -0.1 -0.3 1.0 0.4 -1.0 0.2 -2.3
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 6.0 0.1 0.3 0.2 0.3 -1.0 0.2 2.5 -0.5 0.2 -0.8 0.0 -0.1 0.5 -1.5
Heel bone mineral density (BMD) T-score, automated (left) 0.9 1.9 8.1 0.8 1.1 1.1 0.9 2.2 1.0 2.2 -1.0 0.7 2.9 1.3 -0.3 -0.9 -0.5
Tinnitus: Yes, but not now, but have in the past 4.4 4.7 8.1 2.2 2.2 2.4 2.2 1.7 2.6 2.8 -2.3 2.3 2.6 2.6 1.3 -0.7 0.9
Qualifications: CSEs or equivalent 0.6 0.8 7.1 0.4 0.3 0.3 0.3 -1.1 0.4 2.7 -0.4 -0.5 0.2 0.5 -0.5 -0.1 -1.1
Serious illness, injury or assault to yourself 0.2 0.2 0.8 -0.3 -0.3 -0.2 -0.6 -0.7 0.1 -0.5 -0.1 0.0 -0.3 0.1 -0.4 -0.9 -0.5
High blood pressure 0.6 1.7 4.1 -2.0 -1.7 -1.7 -1.3 -0.4 -1.5 -0.7 1.5 -1.5 0.0 -1.3 -1.5 -0.0 -1.2
Hayfever, allergic rhinitis or eczema 3.0 6.5 12.1 2.6 2.8 2.9 3.5 2.3 3.1 0.9 -2.8 2.4 3.2 3.2 1.2 -1.7 1.3
Multivitamins +/- minerals 0.2 0.3 1.6 0.6 0.4 0.5 1.3 0.4 0.5 0.5 -0.7 0.3 0.8 0.5 0.2 -0.3 0.1
Stomach or abdominal pain in last month 3.4 4.2 7.2 2.2 2.4 2.5 1.5 1.7 2.7 2.6 -2.4 2.0 1.0 2.5 2.2 0.3 1.1
Supplements: Glucosamine 0.2 0.2 0.7 -0.4 -0.4 -0.4 -0.0 0.4 -0.3 -0.4 0.3 -0.5 0.8 -0.2 -0.6 -0.8 -0.2
Diverticular disease/diverticulitis (self-reported) 1.5 1.8 3.7 1.5 1.4 1.4 1.1 1.4 1.3 0.7 -1.0 1.3 0.7 1.4 1.9 1.1 1.9
Medication: Atenolol 0.2 0.2 2.4 0.1 0.2 0.1 0.5 0.4 -0.1 1.5 0.1 0.1 0.1 0.1 -0.5 0.0 -0.4
Medication: Levothyroxine sodium 0.2 0.3 0.9 0.4 0.7 0.6 0.6 0.2 0.5 0.9 -0.7 0.6 -0.2 0.6 -0.0 0.1 -0.7
Sitting height 0.2 1.7 7.7 -1.3 -1.3 -1.3 0.5 1.8 -1.3 -0.3 1.5 -1.4 2.8 -1.1 -0.7 0.0 0.7
Chronic bronchitis/emphysema (father) 1.8 2.2 7.0 1.2 1.4 1.4 0.9 -0.6 1.5 2.6 -1.2 1.1 0.7 1.2 2.2 2.0 0.9
High blood pressure (mother) 0.1 0.1 0.7 -0.1 -0.2 -0.1 -0.8 0.0 0.3 -0.3 -0.2 -0.2 -0.2 0.2 0.1 0.1 -0.1
Body mass index (BMI) 3.2 13.5 34.6 -3.1 -2.7 -2.8 -4.2 -5.1 -2.9 5.9 2.5 -2.7 -5.2 -3.3 -2.1 0.3 -4.7
Impedance of leg (left) 11.3 55.0 104.0 7.9 7.8 7.9 8.1 9.3 7.9 -0.9 -7.1 6.7 10.2 8.4 6.5 1.3 7.5
Leg predicted mass (left) 1.8 9.4 20.1 -3.1 -2.9 -3.0 -2.4 -3.2 -3.0 4.3 2.8 -2.7 -2.4 -3.3 -3.0 -0.8 -4.5
Trunk fat mass 0.6 2.7 31.8 0.5 0.9 0.8 0.4 -0.2 0.7 5.6 -0.7 0.3 0.7 0.5 0.5 0.3 -1.4
Waist circumference 0.8 2.8 30.0 -0.7 -0.3 -0.3 -0.5 -1.1 -0.3 5.5 0.4 -0.3 -0.9 -0.6 -0.2 0.7 -2.4
Number of incorrect matches in round 2.9 4.8 6.8 -2.1 -2.2 -2.3 -2.6 -2.4 -2.4 -2.2 2.0 -2.4 -2.5 -2.3 -2.1 -1.6 -0.8
Past tobacco smoking 4.2 7.7 23.3 3.0 2.9 2.9 1.6 4.8 2.8 0.3 -2.6 2.6 3.6 3.2 1.8 -0.6 2.8
Alcohol usually taken with meals 0.6 0.9 3.1 0.1 0.0 0.2 0.7 1.1 0.4 -1.8 -0.4 0.1 1.7 0.5 -1.0 -1.8 -0.5
Nervous feelings 10.8 20.2 27.4 5.1 5.2 5.2 4.6 4.4 5.2 3.5 -4.7 5.0 5.1 5.1 4.0 1.2 2.3
Frequency of tenseness / restlessness in last 2 weeks 5.9 9.2 22.7 3.4 3.4 3.5 2.2 1.2 3.5 4.8 -3.1 2.7 1.4 3.3 3.7 2.7 1.7
Hearing difficulty/problems with background noise 0.6 1.0 1.7 -1.1 -1.1 -1.1 -0.8 -0.9 -1.1 -1.0 1.3 -0.8 -0.9 -1.3 0.3 1.2 0.3
Hair/balding pattern: Pattern 2 1.4 1.8 7.7 1.5 1.6 1.5 1.4 -0.0 1.3 2.8 -1.2 1.4 0.1 1.0 0.1 -0.6 -1.5
Had menopause 2.3 2.9 8.1 -1.8 -2.0 -1.9 -1.7 -1.4 -1.6 -0.7 1.6 -1.4 -2.8 -1.6 -2.0 -0.8 -1.6
Had other major operations 2.1 2.5 11.1 0.8 0.9 1.0 1.0 -0.9 1.2 3.3 -1.3 0.7 -0.9 1.0 -1.3 -2.4 -2.8
Forced vital capacity (FVC) 0.3 1.3 3.8 0.1 -0.2 -0.2 0.8 1.8 -0.4 -1.7 0.6 0.5 1.5 -0.4 -1.6 -2.0 -1.3
Heel bone mineral density (BMD) T-score, automated (right) 2.0 4.6 13.9 1.8 2.1 2.0 1.7 3.7 2.0 2.3 -1.8 1.8 3.7 2.5 0.5 -0.2 0.7
Ever unenthusiastic/disinterested for a whole week 8.9 10.9 25.4 3.9 4.0 3.9 4.0 0.8 3.8 5.0 -3.6 3.6 1.9 3.5 2.6 0.8 -0.2
Qualifications: None of the above 1.3 2.7 21.8 -0.5 -0.4 -0.4 -0.2 -2.6 -0.4 4.7 0.7 -0.5 -1.2 -0.6 0.1 1.8 -1.5
Financial difficulties in last 2 years 2.4 3.3 10.3 1.4 1.5 1.5 0.8 0.9 1.7 2.0 -1.4 0.8 1.2 1.6 3.2 3.0 2.2
Mouth/teeth dental problems 1.2 1.8 9.1 0.7 0.6 0.5 0.2 2.1 0.4 -2.0 -0.3 0.7 1.1 0.7 1.2 1.7 3.0
Heart attack 1.3 1.7 3.8 -1.4 -1.3 -1.3 -1.8 -1.8 -1.0 1.2 1.3 -1.1 -1.9 -1.0 -0.9 0.1 -1.1
Allergy 3.2 7.4 17.3 -2.5 -2.7 -2.8 -4.2 -2.3 -3.0 -3.0 2.9 -2.7 -2.6 -3.0 0.2 3.0 1.0
Pain all over the body in last month 0.8 0.9 6.3 0.4 0.6 0.5 0.0 -0.8 0.4 2.5 -0.4 0.6 -0.5 0.4 1.0 1.5 0.4
Diabetes (self-reported) 0.5 0.7 6.5 0.1 0.3 0.2 0.2 0.6 0.1 2.6 -0.2 0.5 0.5 0.1 0.1 1.1 -1.1
Hayfever/allergic rhinitis (self-reported) 2.2 3.0 10.6 1.2 1.5 1.5 2.1 2.4 1.8 0.7 -1.3 1.5 3.2 1.8 1.3 0.3 1.4
Medication: Ramipril 1.1 1.4 6.5 -0.8 -0.7 -0.7 -0.8 -1.1 -0.6 0.5 0.7 -0.0 -1.7 -0.7 -1.7 -1.6 -2.6
Medication: Simvastatin 2.8 4.1 7.0 -2.5 -2.3 -2.4 -2.6 -1.5 -2.4 -1.2 2.1 -2.1 -2.3 -2.3 -1.6 -0.2 -1.0
Fluid intelligence score 1.0 2.0 20.5 -0.8 -1.0 -0.9 -0.8 -0.3 -0.9 -4.5 1.0 -0.7 -0.1 -1.0 0.4 1.0 0.7
Illnesses of siblings 2.9 4.1 7.8 -2.4 -2.5 -2.6 -1.2 -0.8 -2.8 -2.4 2.5 -2.3 -1.1 -2.7 -1.7 0.4 -0.2
Neuroticism score 10.5 21.9 33.7 5.3 5.4 5.6 3.9 2.4 5.8 5.8 -5.4 5.0 3.8 5.4 5.0 2.0 1.8
Weight 1.1 5.6 38.7 -1.7 -1.3 -1.4 -1.3 -2.1 -1.4 6.2 1.3 -1.4 -1.2 -1.8 -1.5 -0.1 -3.7
Impedance of arm (right) 8.4 39.0 72.9 6.5 6.2 6.3 6.8 8.0 6.2 -4.0 -5.8 5.3 8.5 6.9 4.8 -0.2 7.5
Arm fat percentage (right) 0.6 2.5 25.6 0.1 0.4 0.3 -0.9 -1.7 0.2 5.1 -0.4 -0.0 -1.6 0.0 0.4 0.5 -1.5
Trunk fat-free mass 1.3 7.6 18.5 -2.9 -2.7 -2.8 -1.5 -2.4 -2.6 4.3 2.7 -2.4 -1.4 -3.1 -2.6 -0.4 -4.3
Hip circumference 1.7 7.5 15.2 -2.8 -2.5 -2.5 -2.8 -3.9 -2.4 3.6 2.2 -2.6 -3.4 -2.7 -1.4 0.6 -3.3
Time employed in main current job 1.8 2.1 5.6 -1.2 -1.1 -1.2 -2.4 -1.9 -1.3 -1.6 1.1 -1.1 -2.4 -1.2 -1.1 -0.3 -0.6
Alcohol intake versus 10 years previously 3.0 4.4 26.1 1.8 2.0 2.0 2.1 0.4 2.1 5.1 -1.7 1.2 1.9 2.1 1.3 1.2 -0.3
Father’s age at death 1.6 2.1 6.5 -1.9 -1.9 -1.8 -0.7 -0.6 -1.4 -2.5 1.3 -1.1 -0.8 -1.4 -1.6 -0.8 -1.0
Worrier / anxious feelings 11.2 21.2 28.4 5.2 5.3 5.3 3.6 4.4 5.2 3.6 -4.7 4.7 4.2 5.1 5.2 2.5 4.5
Frequency of tiredness / lethargy in last 2 weeks 3.0 4.8 10.8 2.7 2.8 2.8 2.3 0.3 2.8 3.3 -2.7 1.9 0.2 2.6 1.5 -0.7 -0.2
Falls in the last year 1.6 2.2 7.2 -1.3 -1.3 -1.2 -0.8 -1.8 -1.1 0.8 0.9 -0.7 -2.1 -1.2 -1.9 -1.4 -2.7
Hair/balding pattern: Pattern 3 0.7 1.0 5.3 -0.6 -0.6 -0.6 -0.2 1.1 -0.7 -2.1 0.8 -0.7 0.7 -0.3 0.0 0.4 2.3
Number of live births 1.5 2.2 7.7 -1.0 -1.1 -1.0 -1.1 -2.3 -0.7 2.7 0.5 -0.7 -1.5 -0.9 -1.2 -0.3 -2.8
Forced expiratory volume in 1-second (FEV1) 0.5 1.8 6.2 1.1 0.9 0.8 1.8 2.5 0.6 -1.1 -0.4 1.4 2.4 0.7 -0.9 -1.1 -1.0
Pulse rate 4.5 7.6 28.4 2.3 2.6 2.4 1.9 5.3 2.2 0.7 -1.7 2.4 4.2 2.5 2.2 1.0 3.6
Happiness 3.0 3.6 6.5 2.2 2.2 2.3 1.9 0.9 2.3 0.7 -2.4 1.9 1.7 2.0 2.5 1.4 0.8
Noisy workplace 1.1 1.4 10.0 0.6 0.9 0.9 0.3 -0.6 1.1 3.2 -1.1 0.9 -0.6 0.8 1.2 1.0 -0.8
Qualifications: A levels/AS levels or equivalent 1.4 3.1 39.8 -0.8 -0.7 -0.7 -0.6 0.2 -0.5 -6.3 0.3 -0.2 -0.1 -0.7 0.2 -0.7 0.8
Serious illness, injury or assault of a close relative in last 2 years 3.4 3.9 7.0 -2.0 -2.1 -2.1 -1.8 -2.6 -2.0 -0.4 1.9 -2.4 -2.4 -2.0 -2.1 -0.8 -1.7
Mouth/teeth dental problems: Dentures 1.3 2.2 11.2 -1.2 -1.0 -1.1 -0.8 -2.0 -1.0 3.3 1.1 -1.2 -2.0 -1.3 0.1 1.0 -1.0
Asthma 2.1 4.1 14.3 1.6 1.6 1.7 2.9 0.8 1.9 3.8 -2.0 1.6 1.0 1.7 -0.7 -2.5 -2.3
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.1 3.5 -0.7 -0.7 -0.7 -1.3 -1.4 -0.6 1.1 0.6 -0.9 -1.2 -0.6 -1.4 -0.6 -1.9
Medication: Cholesterol lowering 2.3 3.6 6.8 -2.6 -2.3 -2.4 -2.0 -1.4 -2.4 -0.6 2.4 -2.1 -1.7 -2.3 -1.3 0.6 -0.5
Depression (self-reported) 1.4 1.6 4.6 1.3 1.4 1.5 0.8 -0.6 1.7 2.1 -1.7 1.1 -0.9 1.5 0.5 -0.8 -0.7
Medication: Lansoprazole 1.0 1.1 5.0 1.0 1.2 1.2 -0.1 -0.2 1.2 2.2 -0.9 0.7 -0.0 1.2 1.1 0.9 0.6
Prospective memory result 1.6 1.9 5.2 1.5 1.7 1.6 1.0 1.0 1.6 2.3 -1.3 1.4 0.6 1.5 1.3 0.2 1.1
Lung cancer (father) 0.7 0.8 5.7 -0.1 -0.0 -0.0 -0.2 -0.7 0.0 1.8 -0.1 -0.0 -0.5 -0.2 1.4 2.4 0.1
Illnesses of mother 0.2 0.2 0.9 -0.1 -0.1 -0.3 0.2 -0.4 -0.5 -0.7 0.5 -0.2 -0.9 -0.4 -0.5 -0.4 0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 1.1 3.6 0.1 -0.1 -0.2 1.0 1.9 -0.5 -1.8 0.6 0.6 1.3 -0.4 -1.4 -0.8 -1.4
Pulse wave Arterial Stiffness index 0.1 0.2 0.8 0.3 0.1 0.0 0.2 0.1 -0.2 0.6 0.4 0.1 0.6 -0.2 -0.1 0.9 -0.7
Impedance of arm (left) 6.9 32.2 63.0 5.8 5.5 5.6 6.2 7.5 5.5 -4.1 -5.2 4.7 7.9 6.2 4.1 -0.4 6.7
Arm fat mass (right) 1.0 4.1 36.5 -0.9 -0.5 -0.6 -1.5 -2.2 -0.7 6.0 0.6 -0.8 -1.9 -0.9 -0.6 0.3 -2.6
Trunk predicted mass 1.3 7.5 17.4 -2.9 -2.8 -2.8 -1.5 -2.3 -2.7 4.2 2.8 -2.4 -1.4 -3.2 -2.5 -0.3 -4.1
Standing height 1.4 13.8 69.1 2.6 2.5 2.6 5.9 6.1 2.8 1.6 -2.0 2.4 8.3 2.8 1.0 -0.8 1.4
Length of working week for main job 1.7 1.9 7.2 -0.9 -0.9 -0.9 -2.7 -1.3 -0.8 -0.6 0.8 -1.0 -2.5 -1.1 -0.6 -0.9 -1.8
Exposure to tobacco smoke at home 1.3 1.5 4.8 -1.2 -1.0 -0.9 -0.4 -1.7 -0.7 2.2 0.9 -0.8 -1.6 -0.9 -0.4 1.0 -1.6
Breastfed as a baby 4.7 5.8 9.8 -3.0 -3.1 -3.1 -1.3 -1.6 -2.9 -2.8 3.1 -2.5 -1.9 -2.9 -2.3 -0.3 -0.5
Tense / ‘highly strung’ 9.9 16.4 25.2 4.8 5.0 5.0 3.8 3.3 5.0 3.9 -4.3 4.7 3.6 4.8 3.4 0.5 1.7
Seen doctor (GP) for nerves, anxiety, tension or depression 2.9 4.4 13.1 2.3 2.5 2.5 2.0 0.5 2.6 3.6 -2.4 2.1 0.9 2.4 1.8 0.2 0.3
Hair/balding pattern: Pattern 4 1.3 3.1 5.0 -2.0 -2.1 -2.0 -2.2 -1.9 -2.0 -1.0 1.6 -2.2 -1.0 -1.8 -1.7 -0.5 -1.6
Birth weight of first child 2.2 3.9 6.3 -2.0 -2.2 -2.1 -1.4 -2.1 -2.0 -1.3 2.1 -1.1 -2.4 -2.2 -2.3 -1.3 -2.5
Peak expiratory flow (PEF) 1.2 2.9 6.2 -1.6 -1.8 -1.8 -1.3 -0.2 -2.0 -2.0 1.7 -1.4 -0.3 -1.8 -2.5 -1.3 -2.3
Pulse wave reflection index 3.0 3.7 11.9 -1.6 -1.8 -1.8 -1.4 -3.5 -1.8 0.5 1.5 -1.4 -2.7 -2.1 -1.3 0.4 -2.8
Ever highly irritable/argumentative for 2 days 8.3 9.9 30.6 3.2 3.3 3.5 3.4 0.1 3.7 5.5 -3.2 2.7 1.4 3.2 3.7 2.2 0.9
Loud music exposure frequency 1.9 2.0 7.3 1.1 1.4 1.3 0.8 1.2 1.2 0.3 -1.0 1.4 0.9 1.0 2.4 2.7 1.4
Qualifications: O levels/GCSEs or equivalent 1.7 2.7 4.6 1.7 1.7 1.8 1.6 2.2 1.8 -1.1 -1.8 1.7 1.4 1.8 1.6 0.1 1.7
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 3.6 0.5 0.3 0.4 0.5 -0.9 0.4 -0.3 -0.5 0.2 0.2 0.3 -0.7 -1.1 -1.9
Blood clot in the leg (DVT) 0.8 1.1 3.4 0.6 0.8 0.7 1.4 1.3 0.7 1.8 -0.6 1.3 0.4 0.8 0.9 1.5 0.7
Medication: Paracetamol 0.7 1.2 8.3 0.8 0.9 0.8 0.3 -0.5 0.7 2.9 -0.5 1.1 -1.4 0.4 1.2 1.0 0.1
Headache pain in last month 0.5 0.9 4.0 1.1 1.1 1.1 0.5 0.3 1.0 2.0 -1.0 0.9 -0.0 0.9 0.9 0.2 0.2
Medication for cholesterol, blood pressure or diabetes 1.9 3.1 5.8 2.4 2.0 2.1 2.0 1.5 2.1 -0.5 -2.1 1.9 1.7 2.0 1.3 -0.5 1.1
Glaucoma (self-reported) 1.0 1.2 3.3 1.2 1.1 1.0 -0.1 0.8 0.8 -1.0 -0.7 0.4 1.3 0.8 1.6 1.3 1.8
Gout (self-reported) 0.4 0.5 1.0 1.0 0.9 0.8 -0.1 0.5 0.5 1.0 -0.6 0.5 0.8 0.4 0.9 0.6 0.3
Hypothyroidism/myxoedema (self-reported) 0.2 0.3 1.5 -0.3 0.1 0.1 -0.5 -0.4 0.1 0.8 -0.3 -0.1 -1.2 0.1 -0.4 -0.7 -0.9
Medication: Amlodipine 1.5 2.1 3.7 -1.6 -1.6 -1.7 -1.9 -1.4 -1.8 -1.1 1.6 -1.7 -1.5 -1.8 -0.4 0.7 -0.2
Medication: Ventolin 100micrograms inhaler 0.7 0.8 8.2 -0.1 0.2 0.2 0.8 0.3 0.5 2.9 -0.4 0.2 1.1 0.4 -0.1 -0.2 -1.0
Birth weight 2.1 4.6 6.7 -2.5 -2.6 -2.5 -2.1 -1.6 -2.5 -1.3 2.4 -2.1 -2.3 -2.6 -2.2 -0.9 -1.6
Chronic bronchitis/emphysema (mother) 1.0 1.1 8.1 -0.5 -0.2 -0.2 0.2 -0.9 0.0 2.8 -0.3 -0.2 -1.0 0.1 -1.1 -0.6 -1.9
High blood pressure (siblings) 1.5 2.1 6.5 1.6 1.6 1.6 1.1 0.5 1.7 2.5 -1.6 1.5 1.4 1.5 0.6 -0.5 -0.9
Forced vital capacity (FVC), Best measure 0.4 1.4 4.6 -0.4 -0.6 -0.7 0.6 1.7 -0.8 -2.2 1.0 0.1 1.1 -0.8 -1.7 -1.5 -1.2
Body fat percentage 0.7 2.9 28.5 1.0 1.4 1.4 0.3 -0.2 1.3 5.3 -1.3 0.7 0.3 1.1 1.1 0.5 -0.8
Leg fat percentage (right) 0.9 3.3 36.0 0.6 1.1 1.0 -0.2 -1.0 0.9 6.0 -0.9 0.4 -0.5 0.7 0.8 0.7 -1.7
Arm fat-free mass (right) 1.8 9.1 25.3 -3.0 -2.8 -2.8 -2.1 -2.9 -2.7 5.0 2.7 -2.5 -1.9 -3.2 -2.7 -0.6 -4.7
Exposure to tobacco smoke outside home 2.0 2.6 8.1 -0.6 -0.6 -0.7 -1.4 -2.7 -1.0 2.8 0.8 -0.8 -2.7 -1.3 -0.6 0.5 -2.5
Comparative body size at age 10 7.0 19.2 39.7 -4.7 -4.9 -4.8 -4.4 -6.3 -4.6 -0.3 4.2 -3.9 -5.8 -5.0 -3.5 -0.0 -4.2
Number of full brothers 0.9 1.1 6.8 0.6 0.5 0.6 0.7 -1.5 0.7 2.6 -0.7 0.6 -1.4 0.3 0.8 0.4 -0.9
Worry too long after embarrassment 3.0 5.0 10.9 2.5 2.4 2.5 1.3 0.8 2.5 -0.2 -2.4 2.5 2.4 2.2 3.3 2.5 1.7
Seen a psychiatrist for nerves, anxiety, tension or depression 4.1 5.4 11.7 2.5 2.8 2.8 2.2 1.1 3.0 3.4 -2.9 2.4 1.0 2.8 1.4 -1.1 -0.3
Wheeze or whistling in the chest in last year 2.4 4.4 25.2 1.4 1.6 1.8 1.8 0.9 2.0 5.0 -2.0 1.4 1.5 1.9 -0.3 -2.4 -1.5
Number of children fathered 0.7 0.7 7.4 0.2 0.2 0.2 0.5 -1.0 0.1 2.7 0.2 -0.4 -0.2 0.2 -0.4 0.4 -1.0
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 1.9 0.4 0.5 0.5 0.6 0.6 0.6 -1.3 -0.8 0.6 0.8 0.5 0.1 -1.4 -0.2
Age at first live birth 2.0 3.6 30.0 -0.2 -0.3 -0.2 0.9 2.1 0.0 -5.5 0.2 0.7 2.6 0.2 0.7 0.1 2.6
Pulse wave peak to peak time 0.2 0.2 0.9 -0.1 0.1 0.2 0.1 0.3 0.4 -0.6 -0.5 0.0 -0.0 0.5 0.3 -0.8 1.0
Health satisfaction 4.5 5.9 10.8 2.6 2.9 2.9 2.5 2.5 2.9 3.3 -2.6 2.5 2.4 2.7 1.6 -0.2 -0.1
Shortness of breath walking on level ground 1.2 1.4 7.9 1.0 1.2 1.1 1.3 0.6 1.1 2.8 -0.8 0.8 -0.1 1.1 -0.3 -0.9 -1.0
Qualifications: College or University degree 1.9 5.8 68.1 0.1 0.0 0.1 -0.9 2.4 0.1 -8.2 -0.1 0.7 0.8 0.2 0.2 -1.4 2.0
Eye problems/disorders: None of the above 4.0 4.6 8.9 -2.6 -2.8 -2.7 -1.8 -2.2 -2.5 -1.7 2.1 -3.0 -2.4 -2.4 -1.3 -0.3 0.2
Mouth/teeth dental problems: Loose teeth 0.5 0.6 2.3 -0.6 -0.7 -0.6 -1.1 -0.9 -0.5 0.8 0.4 -0.6 -0.9 -0.9 -0.2 -0.4 -1.5
Emphysema/chronic bronchitis 1.6 1.8 6.7 -1.1 -1.3 -1.2 -1.5 -1.2 -1.1 -0.2 1.1 -0.7 -1.0 -1.3 -1.7 -1.5 -2.6
Medication for pain relief, constipation, heartburn 0.4 0.7 2.9 0.2 0.2 0.3 1.2 0.7 0.3 -1.6 -0.2 0.0 1.7 0.7 -0.2 -0.4 1.0
Neck or shoulder pain in last month 0.6 0.8 7.9 -0.2 -0.1 -0.0 0.5 -0.8 0.2 2.8 -0.2 -0.2 0.2 0.1 0.4 0.8 -1.2
Medication: Blood pressure 1.0 1.8 3.2 -1.8 -1.5 -1.5 -1.4 -1.3 -1.3 0.7 1.4 -1.1 -1.4 -1.2 -1.5 -0.2 -1.6
Angina (self-reported) 0.5 0.6 2.9 -0.2 -0.2 -0.2 -1.0 -0.3 -0.0 -0.1 0.5 -0.1 -0.6 -0.0 1.3 1.5 1.7
Migraine (self-reported) 0.3 0.3 1.2 0.7 0.6 0.6 0.6 -0.1 0.4 1.1 -0.6 0.6 0.5 0.2 0.6 0.4 -0.5
Medication: Ibuprofen 1.5 1.8 6.1 -1.0 -1.0 -1.0 -1.5 -2.2 -0.8 0.7 0.7 -1.3 -1.6 -0.9 -1.4 -0.7 -2.5
Medication: Allopurinol 0.6 0.8 1.5 1.2 1.2 1.1 0.1 0.9 0.9 0.9 -1.1 1.1 0.9 0.8 0.7 0.1 -0.0
Medication: Omeprazole 1.2 1.4 9.5 0.7 0.8 0.9 1.1 0.2 1.0 3.1 -1.0 1.0 -0.4 0.9 -0.1 -0.6 -1.6
Medication: Seretide 50 evohaler 0.6 0.7 5.9 0.3 0.7 0.6 0.6 -0.2 0.6 2.4 -0.4 0.7 0.2 0.4 -0.0 -0.6 -1.1
Mean time to correctly identify matches 1.9 3.5 13.1 -1.5 -1.5 -1.6 -2.5 -2.2 -1.7 -2.4 1.5 -1.4 -3.6 -1.9 -0.9 0.1 -0.9
Heart disease (mother) 0.4 0.5 1.1 -0.6 -0.8 -0.7 -1.0 -1.0 -0.5 -0.9 0.4 -0.9 -0.7 -0.6 0.3 0.5 0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 1.9 -0.7 -0.8 -0.8 -0.8 -0.7 -0.7 -1.4 0.5 -0.5 -0.7 -0.7 -0.9 -0.3 -1.4
Whole body fat mass 0.8 3.2 38.2 -0.3 0.2 0.1 -0.4 -1.1 0.1 6.2 -0.1 -0.3 -0.4 -0.2 0.1 0.4 -2.1
Leg fat mass (right) 1.1 4.2 42.4 -0.7 -0.2 -0.3 -1.0 -1.9 -0.3 6.5 0.3 -0.7 -1.0 -0.6 -0.3 0.6 -2.8
Arm predicted mass (right) 1.4 7.4 30.8 -2.5 -2.2 -2.3 -1.8 -2.6 -2.2 5.5 2.3 -2.0 -1.5 -2.7 -2.1 -0.2 -4.2
Pulse rate, automated reading 3.9 12.6 51.0 2.8 3.4 3.1 2.1 7.1 2.8 2.6 -2.3 2.8 5.7 3.1 2.8 0.8 3.9
Alcohol intake frequency. 1.2 2.7 23.7 0.7 0.9 0.9 0.6 0.9 1.0 4.9 -1.0 0.5 1.7 1.1 1.2 1.8 0.2
Comparative height size at age 10 0.5 2.8 14.2 1.0 0.9 0.8 2.3 3.8 0.5 -1.3 -0.2 1.1 3.3 0.6 0.3 -0.5 1.7
Number of full sisters 1.1 1.3 7.7 0.6 0.6 0.5 0.2 -1.3 0.3 2.8 -0.5 0.2 -1.1 0.0 0.7 1.5 -1.8
Suffer from ‘nerves’ 3.5 5.4 8.4 2.7 2.8 2.8 1.9 2.2 2.9 1.8 -2.7 2.9 1.7 2.6 2.5 -0.0 1.3
Overall health rating 4.4 9.5 45.7 3.2 3.4 3.4 2.4 1.0 3.4 6.8 -3.1 2.4 1.4 3.2 2.6 0.9 0.1
Chest pain or discomfort 1.0 1.5 8.8 1.1 1.1 1.1 0.9 0.2 1.1 3.0 -1.1 0.6 0.6 1.1 -0.1 -1.4 -0.8
Had major operations 2.3 2.6 7.8 1.6 1.5 1.5 1.7 -0.3 1.5 2.8 -1.1 1.9 1.2 1.2 2.1 2.2 0.4
Age at last live birth 2.2 3.1 30.6 -0.9 -1.0 -0.9 -0.0 2.0 -0.6 -5.5 0.7 -0.0 1.2 -0.6 -0.0 -1.0 1.8
Family relationship satisfaction 2.7 3.4 5.7 2.1 2.1 2.2 2.1 0.8 2.4 1.9 -2.2 1.6 1.8 2.3 1.8 0.5 0.4
Leg pain on walking 1.1 1.4 13.3 -0.2 -0.1 -0.1 0.0 -0.5 -0.2 3.6 0.2 -0.7 -0.9 0.0 -0.8 0.8 -1.7
Qualifications: NVQ or HND or HNC or equivalent 1.5 1.8 8.7 1.5 1.5 1.4 0.7 0.5 1.4 3.0 -1.7 1.1 1.0 1.4 0.6 -0.5 -0.4
Commuting to job workplace: Car/motor vehicle 1.0 1.1 4.4 -0.5 -0.5 -0.5 -0.4 -1.9 -0.5 2.1 0.5 -1.2 -0.7 -0.6 -0.4 0.7 -1.7
Illness, injury, bereavement, stress in last 2 years 0.1 0.2 0.6 0.6 0.6 0.5 0.3 0.2 0.4 -0.3 -0.5 0.8 -0.3 0.4 0.2 -0.0 0.0
Medication: Aspirin 1.2 1.5 3.1 -1.6 -1.8 -1.7 -1.5 -0.0 -1.5 -1.2 1.4 -1.5 -0.4 -1.5 -0.5 0.5 0.0
Supplements: Vitamin C 0.2 0.2 0.8 -0.2 -0.3 -0.1 0.5 0.6 0.1 -0.6 -0.2 -0.5 0.9 0.1 -0.2 -0.7 0.4
Knee pain experienced in last month 1.1 1.7 10.9 -0.5 -0.4 -0.3 0.1 -1.4 -0.0 3.3 -0.0 -0.7 -1.2 -0.1 -1.1 -1.0 -2.6
Hypertension (Self-reported) 0.4 1.2 3.2 -1.8 -1.4 -1.4 -1.3 -0.2 -1.2 -0.7 1.1 -1.1 -0.2 -1.0 -1.1 -0.0 -1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.2 1.4 5.2 1.0 1.1 1.2 1.2 1.6 1.3 2.3 -1.2 0.9 1.1 1.4 0.6 0.3 0.3
Illnesses of father: Heart disease 0.4 0.6 1.1 -1.1 -0.9 -0.9 -0.8 -0.9 -0.7 -0.1 0.7 -0.6 -0.5 -0.7 -0.9 -0.5 -0.8
Illnesses of siblings: Diabetes 4.9 6.0 13.8 2.3 2.6 2.6 2.7 1.3 2.7 3.7 -2.3 2.5 1.9 2.5 2.9 2.1 1.3
Smoking status: Previous 6.7 10.0 24.9 -3.5 -3.5 -3.5 -2.0 -5.0 -3.4 -1.0 3.1 -3.1 -3.4 -3.6 -2.6 -0.2 -3.3
Forced expiratory volume in 1-second (FEV1), predicted 2.6 5.3 13.0 2.3 2.3 2.3 3.6 2.9 2.2 1.9 -2.0 2.2 3.6 2.1 0.3 -1.5 -0.6
Whole body fat-free mass 1.5 8.6 20.8 -3.0 -2.8 -2.8 -2.0 -2.8 -2.8 4.6 2.8 -2.5 -1.8 -3.2 -2.7 -0.6 -4.5
Leg fat-free mass (right) 1.8 9.5 18.3 -3.2 -3.1 -3.1 -2.7 -3.0 -3.2 3.7 3.0 -2.8 -2.6 -3.5 -3.0 -0.9 -4.3
Arm fat percentage (left) 0.7 2.6 24.6 -0.2 0.2 0.1 -1.2 -1.9 0.0 5.0 -0.2 -0.3 -1.7 -0.2 0.1 0.3 -1.8
Average weekly red wine intake 3.3 4.8 13.3 -2.4 -2.3 -2.4 -1.9 -0.3 -2.5 -3.6 2.1 -2.0 -1.1 -2.4 -2.5 -2.1 -1.0
Handedness (chirality/laterality): Left-handed 0.2 0.3 1.0 0.3 0.0 0.0 -0.6 0.6 -0.1 -1.0 0.2 0.4 1.0 -0.0 0.1 0.5 0.9
Mood swings 4.9 8.8 27.4 3.2 3.4 3.5 1.7 0.3 3.7 5.2 -3.3 2.8 1.2 3.3 3.4 1.7 0.4
Loneliness, isolation 1.7 2.3 9.9 1.5 1.5 1.6 1.6 0.7 1.7 3.1 -1.8 1.1 1.4 1.5 0.9 -0.1 -0.5
Long-standing illness, disability or infirmity 0.9 1.4 8.5 0.5 0.5 0.5 0.3 -0.0 0.6 2.7 -0.6 0.8 -0.6 0.2 -0.6 -1.1 -2.9
Ever had bowel cancer screening 1.3 1.5 9.7 -1.1 -1.3 -1.2 -0.8 0.2 -1.1 -3.1 0.9 -1.1 0.1 -0.9 -0.9 -1.3 0.5
Diabetes diagnosed by doctor 0.4 0.6 4.7 -0.0 0.2 0.1 0.2 0.5 0.1 2.2 -0.2 0.4 0.7 0.0 -0.0 0.8 -1.4
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 1.0 -0.5 -0.6 -0.4 -1.0 -0.6 -0.1 0.1 0.2 -0.4 -0.0 -0.5 0.7 1.0 -0.1
Friendships satisfaction 5.4 6.7 9.2 3.0 3.0 3.0 2.9 2.0 3.0 -0.2 -2.9 2.6 2.8 2.9 3.0 0.9 2.2
Qualifications: nursing, teaching 0.7 1.2 10.0 -0.9 -0.7 -0.7 -0.5 -0.7 -0.6 -3.2 0.6 -0.2 -1.0 -0.6 -0.6 -1.1 -0.1
Commuting to job workplace: Walk 0.8 0.9 5.7 -0.1 -0.4 -0.5 -1.2 1.1 -0.6 -2.4 0.6 0.1 -0.6 -0.6 -0.2 -1.1 0.9
Eye problems/disorders: Cataract 0.2 0.3 1.4 0.4 0.5 0.4 0.2 0.5 0.2 0.2 0.0 0.9 0.1 0.2 -0.5 -0.4 -1.2
Mouth/teeth dental problems: Mouth ulcers 0.8 1.2 5.5 0.2 0.2 0.3 1.4 -0.5 0.5 1.5 -0.7 0.1 0.6 0.4 -1.2 -2.1 -2.4
Medication for cholesterol 0.2 0.3 0.8 0.6 0.4 0.4 0.2 -0.9 0.2 -0.9 -0.2 0.3 -0.4 0.0 0.9 0.5 0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.2 2.7 1.5 1.4 1.3 0.6 0.6 1.2 1.6 -1.0 0.6 0.9 1.0 1.4 0.8 0.5
Back pain experienced in last month 0.5 0.7 4.1 0.8 0.8 0.8 -0.0 0.6 0.8 2.0 -1.0 -0.2 -0.0 0.9 -0.1 -1.0 -0.3
Mineral and other dietary supplements 0.5 0.7 1.8 1.1 1.1 1.1 0.6 0.8 0.9 0.6 -1.0 1.3 0.0 0.8 0.8 0.3 0.3
Breast cancer (self-reported) 1.6 2.0 4.0 -1.3 -1.4 -1.6 -1.2 -1.7 -1.8 0.6 1.6 -1.4 -2.0 -1.8 -1.0 0.7 -0.7
Asthma (self-reported) 2.1 4.2 14.9 1.5 1.6 1.6 2.9 0.6 1.8 3.9 -2.0 1.6 0.9 1.7 -1.0 -2.8 -2.5
Osteoporosis (self-reported) 0.8 1.0 3.8 -0.6 -0.7 -0.6 -0.8 -2.0 -0.4 0.3 0.5 -0.4 -1.8 -0.5 -0.9 -1.1 -1.1
Osteoarthritis (self-reported) 1.2 1.5 9.6 1.1 1.2 1.2 0.6 0.5 1.2 3.1 -1.0 0.9 0.4 1.3 -0.0 -0.8 -0.9
Medication: Aspirin 1.1 1.4 2.9 -1.6 -1.7 -1.6 -1.6 -0.2 -1.4 -1.2 1.3 -1.3 -0.2 -1.5 -0.4 0.4 -0.0
Medication: Gliclazide 1.3 1.5 3.6 1.3 1.4 1.5 0.9 0.5 1.7 1.9 -1.6 1.0 0.7 1.5 0.9 -0.3 -0.2
Illnesses of father: None of the above (group 1) 0.2 0.2 1.4 0.7 0.5 0.4 0.1 -0.4 0.2 0.3 -0.2 0.4 -1.2 0.2 0.3 0.2 -0.2
Smoking status: Current 0.4 0.7 4.0 -0.2 -0.1 -0.2 -0.3 -1.1 -0.3 2.0 0.4 -0.3 -1.5 -0.5 0.4 1.0 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.6 1.2 5.5 -0.8 -1.0 -1.1 -1.4 0.1 -1.3 -2.4 1.1 -0.3 -0.4 -1.2 -1.0 -0.1 -0.6
Whole body water mass 1.5 8.6 21.6 -2.9 -2.7 -2.8 -2.0 -2.8 -2.7 4.7 2.7 -2.4 -1.9 -3.2 -2.7 -0.6 -4.5
Leg predicted mass (right) 1.9 9.9 18.3 -3.3 -3.2 -3.2 -2.7 -3.1 -3.3 3.6 3.1 -2.8 -2.6 -3.6 -3.1 -0.9 -4.3
Arm fat mass (left) 1.1 4.4 36.0 -1.0 -0.6 -0.7 -1.5 -2.4 -0.8 6.0 0.6 -0.9 -2.0 -1.0 -0.7 0.1 -3.0
Number of self-reported non-cancer illnesses 3.1 5.5 16.0 2.1 2.5 2.5 2.3 2.4 2.7 4.0 -2.3 2.5 2.2 2.6 1.3 -0.1 -0.0
Average weekly champagne plus white wine intake 0.3 0.4 3.0 0.0 -0.1 0.1 -0.0 -0.8 0.3 -1.7 -0.4 -0.1 -0.4 0.2 -0.1 -1.3 -0.4
Miserableness 5.5 9.5 37.7 3.5 3.6 3.6 1.6 -0.6 3.6 6.1 -3.5 3.2 0.9 3.2 2.5 0.7 -0.9
Guilty feelings 1.1 1.7 8.8 1.4 1.2 1.3 0.4 -1.4 1.4 3.0 -1.4 0.9 -0.3 1.1 1.2 0.8 -0.5
Wears glasses or contact lenses 0.3 0.4 3.2 -0.5 -0.5 -0.4 0.2 -0.8 -0.2 0.5 0.3 -0.3 -0.0 -0.2 0.6 1.8 0.5
Ever taken oral contraceptive pill 2.3 2.6 12.2 -1.2 -1.1 -1.1 -1.3 -3.5 -1.0 0.5 0.8 -1.5 -1.9 -0.9 -1.9 -1.1 -2.3
Hearing aid user 0.2 0.2 1.1 0.3 0.3 0.3 0.5 0.4 0.2 0.6 -0.3 0.2 -0.4 0.1 0.7 1.1 0.3
Mother’s age at death 1.3 1.7 5.1 0.9 1.0 1.1 1.2 2.3 1.2 -0.9 -1.1 1.7 1.9 1.2 1.0 -0.0 1.3
Financial situation satisfaction 1.0 1.3 6.4 0.8 1.0 1.0 1.1 0.2 1.2 2.5 -1.1 0.5 1.5 1.0 0.6 0.1 -1.1
Tinnitus: Yes, now most or all of the time 0.3 0.4 3.1 -0.2 -0.2 -0.2 0.3 1.8 -0.5 -0.3 0.1 0.1 0.2 -0.1 -0.8 -0.7 0.6
Commuting to job workplace: Public transport 0.8 0.9 4.6 -0.9 -0.8 -0.8 -1.1 0.5 -0.7 -2.1 1.1 -0.3 -1.0 -0.8 0.3 0.5 1.1
Eye problems/disorders: Glaucoma 2.2 2.6 4.1 2.0 2.0 2.0 0.6 1.7 1.9 0.6 -1.6 1.4 1.6 1.8 1.9 0.9 1.6
Medication: Blood pressure 0.1 0.2 1.2 -0.4 -0.3 -0.3 -0.4 1.1 -0.2 -0.3 0.1 -0.1 0.7 -0.1 -0.6 -0.5 -0.7
Pain type(s) experienced in last month: Hip pain 1.5 1.8 7.2 -1.0 -1.0 -0.9 -0.2 -1.0 -0.7 1.9 0.7 -1.2 -1.2 -0.7 -2.1 -1.5 -2.7
Supplements: Fish oil (including cod liver oil) 1.5 2.0 4.5 -1.8 -1.8 -1.8 -1.5 -0.5 -1.6 -1.8 1.5 -2.1 0.0 -1.3 -0.6 0.5 0.8
High cholesterol (Self-reported) 3.7 6.6 15.7 -3.3 -3.0 -3.1 -4.0 -1.2 -3.0 -2.4 2.7 -3.0 -2.1 -2.9 -0.8 1.2 0.6
Medication: Bendroflumethiazide 1.0 1.5 4.1 -1.8 -1.6 -1.5 -2.0 -0.4 -1.2 -0.5 1.1 -1.5 -0.9 -1.1 -0.0 0.6 0.5
Medication: Paracetamol 0.9 1.4 9.5 0.9 1.0 1.0 0.2 -0.6 0.9 3.1 -0.6 1.0 -1.6 0.7 1.1 0.6 -0.1
Medication: Lisinopril 0.1 0.2 0.8 0.1 0.1 0.1 -0.2 0.9 0.1 0.3 0.4 0.2 0.8 0.4 -0.5 0.3 0.2
Medication: Atorvastatin 1.4 1.7 4.1 -2.0 -1.7 -1.7 -1.1 -0.7 -1.6 -0.0 1.5 -0.9 -0.7 -1.6 -0.3 1.8 -0.4
Illnesses of father: High blood pressure 1.0 1.3 6.8 0.8 0.9 0.9 1.4 1.3 1.1 -0.0 -1.0 1.0 2.6 1.2 0.1 0.0 -0.6
Alcohol drinker status: Never 0.1 0.2 0.7 0.1 0.2 0.1 -0.3 0.8 0.1 -0.1 -0.2 0.3 0.9 0.1 0.4 0.4 0.2
Ever smoked 2.2 3.9 15.2 -1.8 -1.7 -1.7 -0.9 -3.9 -1.8 0.2 1.6 -1.7 -3.0 -2.1 -1.3 0.2 -2.4
Basal metabolic rate 1.3 7.0 28.4 -2.4 -2.2 -2.2 -1.6 -2.4 -2.2 5.3 2.2 -2.0 -1.5 -2.6 -2.2 -0.5 -4.3
Leg fat percentage (left) 0.8 2.9 32.9 0.3 0.8 0.7 -0.6 -1.0 0.6 5.7 -0.6 0.2 -0.8 0.4 0.8 0.9 -1.5
Arm fat-free mass (left) 1.4 7.0 31.5 -2.4 -2.1 -2.2 -1.6 -2.4 -2.1 5.6 2.1 -1.9 -1.6 -2.6 -2.0 -0.1 -4.1
Number of operations (self-reported) 1.9 2.9 19.9 1.1 1.1 1.2 1.2 -1.9 1.3 4.5 -1.1 1.1 -1.1 1.0 0.3 0.2 -2.1
Average weekly beer plus cider intake 1.9 2.8 25.0 0.9 1.3 1.1 1.3 -1.2 0.9 5.0 -0.7 1.0 -0.1 0.8 -0.0 0.5 -1.9
Irritability 1.2 2.1 5.8 1.6 1.6 1.6 0.2 0.2 1.6 1.8 -1.2 1.5 -0.4 1.2 2.4 2.0 0.6
Risk taking 0.3 0.4 3.2 -0.2 -0.3 -0.2 1.0 0.3 -0.1 1.8 0.0 -0.4 0.4 0.0 0.1 0.8 0.1
Ever had prostate specific antigen (PSA) test 1.2 1.4 2.9 1.2 1.0 1.2 1.5 0.8 1.4 0.3 -1.5 1.2 1.5 1.5 -0.0 -1.7 -0.3
Fractured/broken bones in last 5 years 0.6 0.8 2.8 -0.9 -0.9 -0.9 -0.3 -0.9 -0.8 -0.7 0.7 -0.7 -1.7 -0.9 -0.6 -0.1 -1.1
Age started oral contraceptive pill 0.7 0.9 5.3 -0.7 -0.7 -0.7 0.0 1.5 -0.5 -2.3 0.7 -0.0 -0.7 -0.4 -0.7 -0.9 1.1
Diastolic blood pressure, automated reading 0.4 1.3 8.5 -0.0 0.3 0.3 -0.5 1.5 0.3 2.9 -0.3 -0.2 1.5 0.4 -1.0 -0.4 -1.7
Ever depressed for a whole week 3.7 4.6 12.8 2.1 2.1 2.2 2.7 -0.6 2.5 3.6 -2.2 1.7 1.0 2.2 2.2 2.1 0.1
Unable to work because of sickness or disability 0.6 0.8 3.1 1.0 1.1 1.0 0.7 0.1 0.8 1.1 -0.8 1.8 -0.8 0.6 0.7 0.1 -0.4
Commuting to job workplace: Cycle 0.3 0.4 1.8 0.1 -0.1 -0.0 -0.2 0.7 0.0 -1.2 0.1 0.8 0.7 0.2 0.5 0.9 1.3
Myopia 0.5 0.7 2.8 0.4 0.4 0.4 1.3 -1.7 0.5 -0.1 -0.6 0.3 -0.2 0.5 -0.8 -1.6 -1.1
Vascular/heart problems diagnosed by doctor 0.5 1.4 3.4 1.9 1.5 1.5 1.5 0.6 1.3 0.2 -1.3 1.2 0.1 1.2 0.9 -0.5 1.2
Cholesterol lowering medication 0.6 0.8 3.2 -0.9 -0.9 -0.8 -1.8 -0.7 -0.5 0.5 0.4 -0.6 -1.4 -0.7 0.7 1.5 -0.0
Medication: Omeprazole (e.g. Zanprol) 0.8 0.9 6.3 0.6 0.8 0.8 0.7 -0.2 0.9 2.5 -0.9 0.9 -0.7 0.8 0.5 -0.1 -0.8
Pain experienced in last month 0.8 1.4 14.3 0.2 0.2 0.1 0.6 1.3 -0.1 -3.8 0.3 0.6 0.7 -0.0 -0.1 -0.4 1.3
Supplements: Calcium 0.2 0.2 0.9 -0.3 -0.4 -0.3 -0.2 -0.8 -0.3 -1.0 0.4 -0.6 -0.4 -0.2 -0.3 0.0 0.4
Basal cell carcinoma (self-reported) 1.3 1.5 8.6 -1.2 -1.3 -1.3 -0.8 -0.1 -1.4 -2.9 1.3 -0.9 -0.1 -1.4 -0.5 0.5 0.4
Heart attack/myocardial infarction (self-reported) 1.3 1.7 4.0 -1.5 -1.4 -1.3 -1.9 -1.7 -1.1 1.0 1.4 -1.2 -2.0 -1.1 -0.8 0.0 -1.1
Deep venous thrombosis (DVT) (self-reported) 1.0 1.3 3.2 0.7 0.8 0.8 1.4 1.5 0.7 1.8 -0.6 1.3 0.3 0.7 1.2 1.8 0.9
Heart disease (siblings) 1.0 1.3 5.7 0.6 0.5 0.6 -0.6 -0.1 0.9 0.0 -0.6 0.3 -0.2 1.0 2.2 1.9 2.4
Alcohol drinker status: Previous 4.5 5.2 14.3 -2.5 -2.4 -2.3 -2.6 -3.4 -2.2 -0.1 2.2 -1.9 -3.8 -2.3 -1.3 0.6 -1.4
Pack years of smoking 5.8 8.6 18.9 -3.4 -3.2 -3.2 -3.6 -2.4 -3.3 -1.2 3.0 -2.8 -4.4 -3.7 -1.7 -0.4 -2.2
Impedance of whole body 10.1 51.3 102.0 7.4 7.3 7.4 7.9 9.4 7.3 -3.0 -6.6 6.2 10.1 7.9 5.8 0.5 8.0
Leg fat mass (left) 1.1 4.3 42.0 -0.8 -0.3 -0.4 -1.2 -1.9 -0.4 6.5 0.4 -0.8 -1.2 -0.7 -0.4 0.6 -2.9
Arm predicted mass (left) 1.4 7.2 32.8 -2.5 -2.1 -2.2 -1.6 -2.5 -2.1 5.7 2.2 -1.9 -1.7 -2.6 -2.0 -0.0 -4.2