Best TWAS P=1.94e-10 · Best GWAS P=9.55e-12 conditioned to 0.000581
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | TLR4 | 0.13 | 0.14 | lasso | 2 | 0.13 | 9.8e-12 | 5.7 | -5.7 | 1.3e-08 | -0.61 | 0.72 | 0.28 | FALSE |
| 2 | NTR | Blood | TLR4 | 0.07 | 0.09 | lasso | 4 | 0.09 | 1.1e-26 | 5.8 | -6.4 | 1.9e-10 | -0.67 | 0.66 | 0.34 | TRUE |
| 3 | YFS | Blood | TLR4 | 0.55 | 0.23 | bslmm | 565 | 0.39 | 9.2e-136 | 5.8 | -6.0 | 2.6e-09 | -0.47 | 0.66 | 0.34 | FALSE |