Best TWAS P=7.8e-12 · Best GWAS P=1.78e-11 conditioned to 0.23
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SUDS3 | 0.08 | 0.04 | blup | 472 | 0.08 | 4.5e-10 | -2.3 | -5.4 | 6.9e-08 | -0.83 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Artery Tibial | SUDS3 | 0.12 | 0.11 | lasso | 4 | 0.09 | 1.3e-07 | 6.7 | 6.7 | 1.8e-11 | 0.97 | 0.02 | 0.98 | FALSE |
| 3 | METSIM | Adipose | SUDS3 | 0.05 | 0.05 | lasso | 6 | 0.05 | 2.2e-07 | 6.7 | 5.5 | 3.6e-08 | 0.86 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SUDS3 | 0.07 | 0.00 | blup | 63 | 0.03 | 1.1e-04 | 6.4 | 5.7 | 1.6e-08 | 0.77 | 0.02 | 0.93 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | TAOK3 | 0.02 | 0.01 | blup | 107 | 0.00 | 1.2e-01 | 6.7 | 5.3 | 9.4e-08 | 0.86 | 0.02 | 0.72 | FALSE |
| 6 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | TAOK3 | 0.04 | 0.02 | blup | 109 | 0.03 | 5.7e-03 | 6.3 | 6.8 | 7.8e-12 | 0.91 | 0.03 | 0.68 | TRUE |