TWAS hub - LOC388789

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Glioblastoma Multiforme	0.2520	0.1280	3.6e-03	0.109	0.034	0.067	NA	0.072	0.00035	3.4e-02	4.5e-03	NA	0.00340
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0396	0.0207	3.3e-03	0.005	0.018	0.011	NA	0.009	0.08900	3.2e-03	2.1e-02	NA	0.03100
3	TCGA	Brain Lower Grade Glioma	0.0871	0.0399	6.4e-05	0.013	0.034	0.034	NA	0.030	0.01100	8.4e-05	9.1e-05	NA	0.00021

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Tense / ‘highly strung’	8.1	13.5	22.8	4.8	3.5	2.3
Ever had prostate specific antigen (PSA) test	7.7	8.8	9.5	3.0	2.9	3.1
Worrier / anxious feelings	7.5	14.1	24.3	4.9	2.8	3.2
Suffer from ‘nerves’	7.1	11.1	20.2	4.5	2.3	2.8
Worry (Nagel 2018)	6.8	14.3	27.4	5.2	2.9	2.6
Age at First Birth	6.6	9.6	19.1	4.4	2.8	1.4
Illnesses of father: High blood pressure	6.0	7.4	10.1	3.2	2.5	2.4
Neuroticism (Nagel 2018)	5.8	13.7	25.0	5.0	3.0	2.7
Neuroticism	5.8	14.1	29.7	5.5	2.4	2.6
Age at last live birth	5.6	8.1	18.6	4.3	1.8	1.5
Irritability	5.2	8.7	12.6	3.5	3.1	2.0
Number of full brothers	5.1	6.5	7.6	-2.7	-2.8	-2.1
Frequency of tenseness / restlessness in last 2 weeks	4.9	7.7	8.2	2.9	2.7	2.8
Number of treatments/medications taken	4.8	8.7	9.2	2.8	3.0	3.0
Severe depression (siblings)	4.6	5.2	7.3	2.7	1.8	2.3
Sensitivity / hurt feelings	4.1	7.1	14.1	3.8	1.3	2.3
Average weekly fortified wine intake	4.1	4.8	5.6	1.9	2.4	2.2
Neuroticism score	4.0	8.4	17.8	4.2	1.8	2.0
Other serious medical condition/disability diagnosed by doctor	3.9	5.1	8.4	0.9	2.9	2.4
Ever had stillbirth, spontaneous miscarriage or termination	3.8	4.1	6.7	2.6	1.0	2.1
HDL Cholesterol	3.7	6.1	8.8	-1.8	-2.5	-3.0
Medication: Lansoprazole	3.7	4.2	8.3	1.6	1.3	2.9
Age when periods started (menarche)	3.5	8.5	13.2	-0.4	-3.6	-3.5
Taking other prescription medications	3.3	5.1	7.2	1.9	2.7	2.1
Prospective memory result	3.3	4.1	7.0	-2.7	-1.8	-1.4
Medication: Ibuprofen	3.1	3.7	10.0	3.2	-0.3	1.0
Qualifications: CSEs or equivalent	3.0	3.9	7.2	-2.0	-2.7	-0.9
Nervous feelings	3.0	5.6	12.7	3.6	1.7	1.2
Relative age voice broke	2.9	4.5	6.7	-2.1	-2.6	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	2.9	4.4	9.0	3.0	1.4	1.5
Eye problems/disorders: Diabetes related eye disease	2.8	3.1	4.2	-1.3	-2.0	-1.9
Had other major operations	2.8	3.4	4.8	1.6	2.2	1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	2.8	3.7	7.2	2.7	1.3	1.5
Relative age of first facial hair	2.7	5.5	11.7	-2.0	-3.4	-0.8
Maternal smoking around birth	2.6	3.7	8.7	-1.5	-2.9	-0.5
Medication for pain relief, constipation, heartburn	2.6	4.5	5.4	-1.9	-2.2	-2.3
Fractured/broken bones in last 5 years	2.6	3.4	6.2	1.6	1.2	2.5
Medication: Co-codamol	2.5	2.9	4.5	1.2	1.6	2.1
Hypothyroidism/myxoedema (self-reported)	2.5	4.8	7.0	1.7	2.2	2.6
Number of self-reported non-cancer illnesses	2.5	4.4	7.7	1.6	2.8	1.7
Diverticular disease/diverticulitis (self-reported)	2.4	2.8	6.6	2.6	1.0	0.9
Fluid intelligence score	2.4	5.0	9.0	1.8	3.0	1.6
Medication: Lisinopril	2.4	3.1	4.8	1.4	2.2	1.6
Ever depressed for a whole week	2.4	2.9	5.4	2.3	1.1	1.5
Coronary Artery Disease (CAD)	2.3	2.7	5.8	2.4	1.3	0.8
Stomach or abdominal pain in last month	2.2	2.8	4.6	1.6	1.2	2.1
Medication: Blood pressure	2.2	4.2	8.4	0.2	2.9	2.0
Average weekly beer plus cider intake	2.2	3.2	5.9	-1.7	-2.4	-0.9
Supplements: Calcium	2.2	2.4	4.0	2.0	1.5	1.0
Knee pain experienced in last month	2.1	3.2	7.2	2.7	0.5	1.5
Pain experienced in last month	2.1	3.5	4.8	-2.2	-1.1	-2.1
Hypothyroidism (self reported)	2.0	4.6	6.1	2.0	2.5	1.9
Supplements: Glucosamine	2.0	2.6	3.8	2.0	1.1	1.7
Worry too long after embarrassment	2.0	3.3	8.6	2.9	0.9	0.7
Heel T-Score	1.9	14.8	20.8	-4.6	-3.1	-3.8
Chronotype (morning person)	1.9	4.4	7.7	1.3	2.8	2.0
Lung cancer (father)	1.9	2.2	5.2	-2.3	-1.1	0.3
Ever highly irritable/argumentative for 2 days	1.9	2.3	2.9	1.2	1.7	1.6
Alcohol intake frequency.	1.9	4.4	7.5	1.9	2.7	1.5
Alcohol drinker status: Never	1.9	2.3	4.6	0.3	2.1	1.5
Major Depression (MDD)	1.8	2.2	4.2	2.1	0.8	1.4
Medication: Atenolol	1.8	2.3	5.2	0.3	2.3	1.2
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.3	6.1	2.5	-0.1	0.9
Headache pain in last month	1.8	3.1	5.8	0.2	2.4	1.8
Age at first live birth	1.8	3.1	9.1	3.0	0.5	-0.2
Ever had bowel cancer screening	1.8	2.1	2.8	1.2	1.7	1.5
Medication: Paracetamol	1.8	2.7	3.4	1.2	1.9	1.8
Pulse wave Arterial Stiffness index	1.7	2.0	3.8	0.7	2.0	1.3
Vascular/heart problems diagnosed by doctor	1.7	4.6	10.2	-0.3	-3.2	-1.9
Diabetes (father)	1.6	2.0	5.1	2.3	-0.9	0.1
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.5	5.6	-2.2	-0.2	-2.4
Length of working week for main job	1.6	1.8	3.1	-0.7	-1.7	-1.3
Neck or shoulder pain in last month	1.6	2.3	4.0	2.0	1.0	1.4
Medication: Aspirin	1.6	2.1	3.1	1.2	1.3	1.8
Prostate Cancer	1.5	2.0	4.9	-2.2	0.3	-1.1
Neuroticism (2016)	1.5	2.1	4.2	2.1	1.4	0.2
Supplements: Zinc	1.5	1.7	4.5	2.1	0.2	0.7
Breastfed as a baby	1.5	1.9	3.1	1.0	1.2	1.8
Gout (self-reported)	1.5	2.1	5.0	-2.2	-0.9	-0.6
Chronic bronchitis/emphysema (mother)	1.5	1.7	3.5	-1.9	-1.2	-0.3
Mood swings	1.5	2.7	3.0	1.6	1.5	1.7
Heart attack/myocardial infarction (self-reported)	1.5	2.0	3.6	-0.6	1.4	1.9
Triglycerides	1.4	2.3	3.7	1.9	1.0	1.5
High blood pressure	1.4	4.0	10.1	0.2	3.2	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	2.4	0.8	1.3	1.5
Mineral and other dietary supplements	1.4	1.9	3.0	-1.7	-1.1	-1.2
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	3.3	0.5	1.8	1.2
Depressed Affect (Nagel 2018)	1.3	2.7	5.7	2.4	1.0	1.2
Crohns Disease (2012)	1.3	2.0	4.5	0.8	2.1	1.0
Lung FEV1/FVC ratio	1.3	6.5	12.3	1.4	3.5	2.3
Townsend deprivation index at recruitment	1.3	1.9	5.3	-2.3	-0.1	-0.6
High blood pressure (mother)	1.3	1.8	3.9	1.1	2.0	0.6
Heart attack	1.3	1.7	3.2	-0.5	1.3	1.8
Medication: Blood pressure	1.3	2.3	3.0	1.6	1.7	1.1
Qualifications: nursing, teaching	1.3	1.9	2.7	1.4	1.7	1.1
Body Mass Index (BMI) (2010)	1.2	1.6	3.2	1.8	0.7	1.0
Cardiovascular Disease	1.2	4.1	9.6	0.3	3.1	1.6
Serious illness, injury or assault to yourself	1.2	1.4	2.7	-0.1	1.6	1.3
Hearing difficulty/problems with background noise	1.2	2.0	4.8	0.4	1.0	2.2
Arm fat percentage (right)	1.2	4.7	11.4	-3.4	-1.6	-0.4
Time employed in main current job	1.2	1.4	2.4	1.0	0.9	1.6
Father’s age at death	1.2	1.6	3.7	1.9	0.2	1.0
Pulse wave peak to peak time	1.2	1.5	3.0	-0.4	-1.7	-1.1
Hypertension (Self-reported)	1.2	3.4	8.6	-0.2	2.9	1.2
Medication: Aspirin	1.2	1.5	2.6	1.0	0.9	1.6
Ulcerative Colitis	1.1	1.6	4.4	0.2	-0.6	-2.1
Systolic Blood Pressure	1.1	5.3	12.7	1.0	3.6	1.5
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.5	4.6	-1.5	-0.8	-2.1
Hair/balding pattern: Pattern 4	1.1	2.7	3.3	1.2	1.8	1.8
Comparative body size at age 10	1.1	3.0	5.7	-0.8	2.4	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.4	1.9	-1.4	-1.4	-0.6
Commuting to job workplace: Car/motor vehicle	1.1	1.2	2.1	-0.8	1.4	1.0
Arm fat percentage (left)	1.1	4.2	10.6	-3.3	-1.4	-0.3
Guilty feelings	1.1	1.7	3.0	1.2	0.8	1.7
Hearing aid user	1.1	1.2	3.2	-1.8	0.3	0.6
Mother’s age at death	1.1	1.4	2.4	-1.2	-0.4	-1.6
Financial situation satisfaction	1.1	1.4	2.0	1.4	1.0	1.0
Mean Putamen Volume	1.0	1.1	1.9	0.2	-1.2	-1.4
Smoking Status	1.0	2.4	5.8	-1.1	-2.4	-0.5
Happiness	1.0	1.2	2.1	1.4	1.2	-0.0
Illnesses of mother	1.0	1.3	2.4	-1.5	-0.5	-1.1
Loud music exposure frequency	1.0	1.1	1.6	1.3	1.2	0.4
Medication: Omeprazole	1.0	1.1	1.8	0.5	1.3	1.2
Friendships satisfaction	1.0	1.2	3.5	1.9	-0.4	-0.1
Eye problems/disorders: Cataract	1.0	1.1	3.0	0.3	0.5	1.7
Wears glasses or contact lenses	1.0	1.2	2.2	0.5	1.0	1.5
Ulcerative Colitis (UC)	0.9	1.6	4.8	0.4	0.1	-2.2
Vitamin and mineral supplements	0.9	1.2	1.6	-0.5	-1.3	-1.3
Medication: Levothyroxine sodium	0.9	1.6	2.4	0.5	1.4	1.6
Long-standing illness, disability or infirmity	0.9	1.4	2.2	1.2	0.9	1.5
Pain type(s) experienced in last month: Hip pain	0.9	1.1	2.9	0.1	1.7	0.6
Verbal and Numeric Reasoning (VNR)	0.8	1.8	3.6	-1.4	-0.3	-1.9
Systolic blood pressure, automated reading	0.8	2.4	5.7	-0.3	2.4	1.1
Current tobacco smoking	0.8	1.3	2.2	-1.2	-1.5	-0.6
Multivitamins +/- minerals	0.8	1.0	1.7	0.6	1.0	1.3
Medication: Paracetamol	0.8	1.3	2.2	0.5	1.3	1.5
Shortness of breath walking on level ground	0.8	1.0	1.5	-1.1	-1.2	0.4
Illnesses of siblings: Diabetes	0.8	1.0	2.6	1.6	-0.2	0.6
Medication for cholesterol	0.8	1.2	2.6	-0.0	-1.6	-1.1
Smoking status: Current	0.8	1.3	2.5	-1.1	-1.6	-0.5
Supplements: Fish oil (including cod liver oil)	0.8	1.0	1.2	0.9	1.0	1.1
Alzheimer’s Disease (in mother)	0.7	0.8	1.3	1.1	0.6	0.8
Breast Cancer	0.7	1.8	3.5	-1.0	-1.9	-0.9
Medication for hormone replacement therapy	0.7	0.8	1.7	-1.3	0.0	-0.8
Body mass index (BMI)	0.7	2.8	7.1	-2.7	-1.1	0.4
Past tobacco smoking	0.7	1.4	2.5	0.8	1.6	1.0
Had menopause	0.7	0.8	1.0	0.9	0.8	1.0
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.4	1.6	-0.3	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	1.5	1.2	0.8	1.2
Falls in the last year	0.7	0.9	1.6	1.3	0.6	0.9
Arm fat mass (right)	0.7	2.8	7.8	-2.8	-0.8	-0.0
Pulse wave reflection index	0.7	0.8	1.3	0.3	1.1	1.1
Body fat percentage	0.7	2.7	7.1	-2.7	-1.0	-0.3
Exposure to tobacco smoke outside home	0.7	0.9	1.8	-0.8	-1.4	-0.5
Medication: Allopurinol	0.7	0.9	1.4	-1.2	-1.1	-0.3
Arm fat mass (left)	0.7	2.8	7.6	-2.8	-0.8	-0.0
Eye problems/disorders: Glaucoma	0.7	0.8	1.7	-1.3	0.9	-0.2
Depression (Nagel 2018)	0.6	0.9	2.2	1.5	0.6	0.3
Hearing difficulty/problems: Yes	0.6	0.9	2.1	-0.1	0.8	1.5
Chronic bronchitis/emphysema (father)	0.6	0.7	1.3	-1.1	-0.9	0.3
Waist circumference	0.6	2.0	5.3	-2.3	-0.7	0.6
Alcohol usually taken with meals	0.6	1.0	2.8	0.1	1.7	0.1
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.1	1.0	0.5	0.9
Financial difficulties in last 2 years	0.6	0.8	1.7	-1.3	-0.4	-0.6
Wheeze or whistling in the chest in last year	0.6	1.0	2.3	-0.7	-1.5	-0.5
Health satisfaction	0.6	0.7	1.5	0.5	-1.2	-0.7
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.3	-0.8	-1.1	-0.3
Emphysema/chronic bronchitis	0.6	0.7	0.8	-0.8	-0.9	-0.7
Comparative height size at age 10	0.6	3.2	7.5	0.7	2.7	1.3
Illnesses of father: Heart disease	0.6	0.8	1.9	1.4	0.3	0.7
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.1	0.8	1.0	0.6
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	2.6	-0.2	-0.1	-1.6
Medication: Bendroflumethiazide	0.6	1.0	1.5	0.8	1.2	0.9
Diastolic blood pressure, automated reading	0.6	1.8	3.6	-1.1	1.9	0.8
Unable to work because of sickness or disability	0.6	0.8	1.6	0.4	0.7	1.3
Alcohol drinker status: Previous	0.6	0.6	1.6	1.3	-0.4	-0.4
Schizophrenia vs Biploar Disorder	0.5	0.6	1.0	-1.0	-0.4	-0.9
LDL Cholesterol	0.5	0.8	1.8	-1.3	-0.8	0.2
Frequency of depressed mood in last 2 weeks	0.5	0.6	1.0	0.7	1.0	0.6
Trunk fat percentage	0.5	2.1	5.5	-2.3	-0.8	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	0.9	0.9	0.7	0.9
Standing height	0.5	4.9	7.6	2.5	2.8	0.9
Blood clot in the leg (DVT)	0.5	0.6	1.0	-0.9	-1.0	0.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.0	-1.0	-0.7	-0.9
Birth weight	0.5	1.1	2.3	-0.9	1.5	-0.4
High blood pressure (siblings)	0.5	0.7	1.5	1.2	0.4	0.6
Leg fat percentage (right)	0.5	1.7	4.0	-2.0	-1.1	0.0
Mean time to correctly identify matches	0.5	0.9	2.5	0.5	1.6	0.0
Whole body fat mass	0.5	1.9	5.4	-2.3	-0.6	-0.1
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.8	1.3	0.1	0.2
Supplements: Vitamin C	0.5	0.6	0.9	0.7	0.8	0.9
Loneliness, isolation	0.5	0.7	1.8	1.3	0.4	0.3
Commuting to job workplace: Walk	0.5	0.6	1.4	0.1	-1.2	-0.6
Back pain experienced in last month	0.5	0.7	1.3	0.8	-0.1	1.2
Commuting to job workplace: Public transport	0.5	0.6	1.2	1.1	0.5	0.6
Ever smoked	0.5	1.0	1.5	-0.5	-1.2	-1.0
Age started oral contraceptive pill	0.5	0.6	1.1	0.8	0.3	1.0
Cholesterol lowering medication	0.5	0.8	1.2	0.6	0.8	1.1
Alzheimer’s Disease (in father)	0.4	0.4	0.6	-0.2	-0.7	-0.8
Crohns Disease (2017)	0.4	0.8	1.5	0.1	1.2	1.0
Ovarian Cancer	0.4	0.6	0.9	1.0	-0.7	0.6
Blood Eosinophil Count	0.4	3.1	3.9	-2.0	-1.7	-1.6
Blood Red Count	0.4	4.1	9.2	3.0	-1.0	1.4
Blood White Count	0.4	2.9	6.9	-2.6	-1.3	-0.4
Waist Hip Ratio (WHR)	0.4	1.6	3.3	-1.8	-0.6	-1.1
Allergy or Eczema	0.4	1.1	3.0	1.7	0.2	0.4
Diabetes (mother)	0.4	0.5	0.9	0.3	-1.0	-0.7
Sitting height	0.4	3.0	4.8	2.2	1.3	1.6
Qualifications: None of the above	0.4	0.9	2.3	-1.5	0.5	0.0
Number of live births	0.4	0.6	1.3	-1.2	-0.4	-0.5
Mouth/teeth dental problems: Dentures	0.4	0.6	1.9	0.1	-0.0	1.4
Depression (self-reported)	0.4	0.5	0.9	1.0	0.7	0.0
Exposure to tobacco smoke at home	0.4	0.5	1.2	0.4	1.1	-0.1
Medication: Ventolin 100micrograms inhaler	0.4	0.6	1.0	-1.0	0.8	0.0
Number of children fathered	0.4	0.4	0.6	0.8	0.3	0.8
Qualifications: College or University degree	0.4	1.2	2.3	1.2	1.5	0.3
Number of full sisters	0.4	0.5	0.9	-0.9	-0.6	0.5
Family relationship satisfaction	0.4	0.5	1.3	1.1	0.4	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	1.8	0.7	0.1	-1.3
Asthma (self-reported)	0.4	0.7	1.8	-0.1	1.4	0.6
Ever taken oral contraceptive pill	0.4	0.5	0.8	-0.2	-0.9	-0.8
Leg fat percentage (left)	0.4	1.6	4.2	-2.1	-0.7	0.0
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	0.9	-0.7	-1.0	0.3
Leg fat mass (left)	0.4	1.5	4.3	-2.1	-0.5	0.0
Alzheimer’s Disease (including proxy)	0.3	0.5	1.0	0.4	1.0	0.4
Irritable Bowel Disease (IBD)	0.3	0.7	1.3	0.3	1.1	-0.8
Fasting Glucose	0.3	0.3	0.8	-0.9	0.3	-0.4
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.7	0.8	-0.6	0.3
BMI	0.3	1.5	3.6	-1.9	0.2	0.9
Height	0.3	6.1	10.1	2.8	3.2	0.6
Ever had hysterectomy (womb removed)	0.3	0.3	0.8	0.2	0.3	0.9
Angina	0.3	0.4	1.0	-0.1	1.0	0.5
Fed-up feelings	0.3	0.6	1.8	1.4	-0.3	0.1
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.9	1.4	0.4	-0.1
Trunk fat mass	0.3	1.4	4.2	-2.0	-0.4	0.1
Pain all over the body in last month	0.3	0.3	0.5	0.7	-0.5	0.3
Medication: Ramipril	0.3	0.4	0.6	0.5	0.7	0.8
Alcohol intake versus 10 years previously	0.3	0.4	0.7	0.9	-0.5	-0.5
Hair/balding pattern: Pattern 3	0.3	0.4	0.6	-0.1	-0.8	-0.8
Asthma	0.3	0.6	1.1	-0.5	1.1	0.6
Medication: Cholesterol lowering	0.3	0.5	1.0	1.0	0.6	0.3
Glaucoma (self-reported)	0.3	0.4	0.8	-0.9	0.6	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.9	0.9	0.5	-0.3
Eye problems/disorders: None of the above	0.3	0.3	0.6	-0.4	-0.3	-0.8
Angina (self-reported)	0.3	0.4	0.8	-0.1	0.9	0.6
Medication: Seretide 50 evohaler	0.3	0.4	1.1	0.2	-1.1	0.1
Leg fat mass (right)	0.3	1.3	3.7	-1.9	-0.6	0.1
Overall health rating	0.3	0.7	1.5	-1.2	0.7	0.1
Had major operations	0.3	0.4	0.9	-1.0	-0.4	-0.3
Smoking status: Previous	0.3	0.4	0.6	0.1	-0.8	-0.7
Diabetes diagnosed by doctor	0.3	0.4	1.0	-0.5	-1.0	-0.1
Illnesses of father: None of the above (group 1)	0.3	0.4	0.6	-0.8	-0.6	-0.5
Miserableness	0.3	0.5	1.4	1.2	0.2	0.3
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.6	-0.4	0.8	0.4
High cholesterol (Self-reported)	0.3	0.5	0.8	0.3	0.9	0.7
Risk taking	0.3	0.5	0.7	-0.8	-0.4	-0.7
Basal cell carcinoma (self-reported)	0.3	0.3	0.4	0.5	-0.4	-0.7
Heart disease (siblings)	0.3	0.3	0.8	0.3	-0.9	0.4
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.5	-1.2	0.4	-0.6
Schizophrenia (2018)	0.2	0.4	0.8	-0.9	-0.3	-0.5
Reaction Time	0.2	0.4	1.1	0.0	1.0	-0.3
HbA1C	0.2	0.3	0.4	-0.6	0.6	0.0
Primary Biliary Cirrhosis	0.2	0.3	0.6	0.8	0.5	0.3
Rheumatoid Arthritis	0.2	0.3	0.9	0.1	0.4	-0.9
Schizophrenia (2014)	0.2	0.4	1.0	-1.0	-0.2	-0.3
Blood Platelet Count	0.2	2.2	3.3	-1.8	1.6	-0.7
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.5	-0.1	0.3	-0.7
Pack years adult smoking proportion	0.2	0.3	0.8	-0.4	-0.9	-0.2
Impedance of leg (right)	0.2	0.9	1.8	1.3	0.1	-1.0
Impedance of leg (left)	0.2	0.9	1.5	1.2	0.7	-0.9
Hair/balding pattern: Pattern 2	0.2	0.2	0.4	0.6	-0.2	-0.5
Mouth/teeth dental problems	0.2	0.3	0.7	0.9	0.2	-0.4
Illnesses of siblings	0.2	0.3	0.7	-0.8	0.2	-0.4
Weight	0.2	0.9	2.4	-1.6	-0.0	0.4
Hip circumference	0.2	0.8	1.5	-0.9	-0.3	1.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	0.9	0.4	0.2	0.9
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.6	0.2	0.8	0.2
Arm fat-free mass (right)	0.2	1.1	2.6	0.1	1.6	0.8
Migraine (self-reported)	0.2	0.3	0.9	0.0	0.2	-0.9
Arm predicted mass (right)	0.2	1.0	2.5	0.1	1.6	0.7
Leg pain on walking	0.2	0.3	0.7	-0.4	-0.3	0.8
Breast cancer (self-reported)	0.2	0.2	0.5	-0.2	-0.3	-0.7
Osteoporosis (self-reported)	0.2	0.2	0.4	0.6	0.5	0.2
Osteoarthritis (self-reported)	0.2	0.2	0.5	0.4	0.2	0.7
Medication: Gliclazide	0.2	0.2	0.4	-0.7	-0.4	-0.1
Number of operations (self-reported)	0.2	0.3	0.7	-0.9	0.4	-0.1
Commuting to job workplace: Cycle	0.2	0.2	0.5	0.1	-0.1	-0.7
Pack years of smoking	0.2	0.2	0.5	-0.4	-0.7	0.1
Bipolar Disorder (2018)	0.1	0.1	0.1	0.4	0.3	-0.2
Bipolar Disorder or Schizophrenia	0.1	0.2	0.2	-0.5	-0.0	-0.5
Bipolar Disorder (2011)	0.1	0.1	0.1	0.3	0.2	-0.0
Lupus	0.1	0.2	0.3	-0.4	0.3	0.6
Respiratory disease	0.1	0.3	0.7	-0.8	0.2	0.5
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.5	-0.3	-0.7	-0.3
Lung FVC	0.1	0.6	0.8	-0.7	-0.9	-0.7
Hand grip strength (right)	0.1	0.3	0.7	0.0	-0.5	-0.8
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.1	-0.2	0.3	0.1
Leg predicted mass (left)	0.1	0.3	0.3	-0.5	0.6	0.5
Number of incorrect matches in round	0.1	0.2	0.4	0.4	0.2	0.7
Forced vital capacity (FVC)	0.1	0.4	1.0	0.3	-0.0	-1.0
Diabetes (self-reported)	0.1	0.2	0.5	-0.0	-0.7	-0.3
Medication: Simvastatin	0.1	0.2	0.3	0.5	0.3	0.5
Impedance of arm (right)	0.1	0.7	1.2	-0.3	-0.8	-1.1
Trunk fat-free mass	0.1	0.6	1.6	0.0	1.3	0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.7	0.5	0.0	-0.8
Pulse rate	0.1	0.2	0.4	-0.2	-0.2	-0.6
Noisy workplace	0.1	0.1	0.3	0.3	-0.1	0.5
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.3	0.1	0.6	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.2	0.5	0.0	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.0	0.4	0.1	-1.0
Impedance of arm (left)	0.1	0.4	0.7	0.1	-0.6	-0.9
Trunk predicted mass	0.1	0.7	1.8	0.0	1.4	0.6
Birth weight of first child	0.1	0.2	0.5	0.0	0.1	-0.7
Peak expiratory flow (PEF)	0.1	0.3	0.6	0.5	-0.8	-0.3
Medication: Amlodipine	0.1	0.2	0.3	-0.1	0.5	0.6
Forced vital capacity (FVC), Best measure	0.1	0.5	1.3	0.4	-0.2	-1.1
Heart disease (mother)	0.1	0.2	0.4	0.2	-0.7	-0.1
Pulse rate, automated reading	0.1	0.2	0.5	0.2	0.0	-0.7
Chest pain or discomfort	0.1	0.1	0.2	0.2	-0.0	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	0.2	-0.4	0.2
Whole body fat-free mass	0.1	0.5	1.1	-0.2	1.1	0.5
Leg fat-free mass (right)	0.1	0.4	0.5	-0.7	0.7	0.5
Average weekly red wine intake	0.1	0.2	0.3	0.6	-0.2	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.2	-0.3	0.4	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.5	0.7	0.4	-0.2
Whole body water mass	0.1	0.4	1.0	-0.4	1.0	0.4
Leg predicted mass (right)	0.1	0.3	0.5	-0.7	0.7	0.4
Average weekly champagne plus white wine intake	0.1	0.1	0.1	0.3	-0.2	0.3
Basal metabolic rate	0.1	0.4	0.5	-0.7	0.7	0.4
Arm fat-free mass (left)	0.1	0.7	1.7	-0.5	1.3	0.5
Myopia	0.1	0.1	0.3	0.6	-0.1	0.2
Impedance of whole body	0.1	0.5	1.0	1.0	0.5	-0.5
Arm predicted mass (left)	0.1	0.6	1.1	-0.7	1.1	0.4
Hair Pigment	0.0	0.2	0.4	0.0	-0.6	0.3
Tanning	0.0	0.1	0.3	-0.1	0.3	0.6
Hand grip strength (left)	0.0	0.1	0.2	-0.1	-0.2	-0.5
Average weekly spirits intake	0.0	0.1	0.1	0.2	0.0	-0.4
Medication: Metformin	0.0	0.0	0.1	-0.3	-0.1	0.1
Leg fat-free mass (left)	0.0	0.2	0.4	-0.7	0.4	0.4
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.1	-0.2	-0.3	0.0
Allergy	0.0	0.1	0.2	-0.5	-0.0	-0.0
Medication: Atorvastatin	0.0	0.0	0.1	0.2	-0.1	-0.0

Hub : Genes

LOC388789

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Trait associations