TWAS hub - LINC00493

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.12700	0.0440	1.9e-04	0.050	NA	0.057	NA	0.042	6.5e-05	NA	2.0e-05	NA	2.3e-04
2	GTEx	Artery Aorta	0.18900	0.0680	3.3e-04	0.013	NA	0.074	NA	0.056	6.4e-02	NA	6.6e-05	NA	5.0e-04
3	GTEx	Artery Tibial	0.17540	0.0415	8.5e-11	0.115	NA	0.167	NA	0.176	2.7e-09	NA	4.2e-13	NA	8.7e-14
4	GTEx	Brain Cortex	0.35000	0.0930	1.0e-06	0.219	NA	0.070	NA	0.119	1.1e-06	NA	5.6e-03	NA	3.7e-04
5	GTEx	Breast Mammary Tissue (Male)	0.00974	0.0599	4.5e-01	0.013	NA	-0.011	NA	-0.013	1.6e-01	NA	7.2e-01	NA	8.9e-01
6	GTEx	Cells Transformed fibroblasts	0.17300	0.0480	1.8e-06	0.060	NA	0.081	NA	0.083	2.6e-05	NA	1.2e-06	NA	8.5e-07
7	GTEx	Esophagus Gastroesophageal Junction	0.49000	0.1110	2.7e-04	-0.007	NA	-0.003	NA	-0.006	6.7e-01	NA	4.2e-01	NA	6.3e-01
8	GTEx	Esophagus Muscularis	0.09400	0.0390	5.3e-03	0.033	NA	0.031	NA	0.019	4.0e-03	NA	5.1e-03	NA	2.5e-02
9	GTEx	Lung	0.07370	0.0267	3.9e-04	0.025	NA	0.007	NA	0.015	4.9e-03	NA	9.0e-02	NA	2.3e-02
10	GTEx	Muscle Skeletal	0.09840	0.0359	1.2e-04	0.029	NA	0.047	NA	0.048	7.4e-04	NA	2.1e-05	NA	1.7e-05
11	GTEx	Nerve Tibial	0.16480	0.0511	1.5e-05	0.024	NA	0.055	NA	0.047	8.0e-03	NA	8.9e-05	NA	2.8e-04
12	GTEx	Testis	0.11100	0.0450	1.6e-03	0.046	NA	0.024	NA	0.033	4.3e-03	NA	3.0e-02	NA	1.3e-02
13	GTEx	Whole Blood	0.17400	0.0480	2.7e-08	0.109	NA	0.090	NA	0.108	3.3e-10	NA	1.1e-08	NA	4.0e-10
14	ROSMAP	Brain Pre-frontal Cortex	0.19020	0.0340	0.0e+00	0.224	0.253	0.273	0.264	0.280	2.6e-28	2.7e-32	4.0e-35	8.9e-34	3.8e-36

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	6	7	8	9	10	11	12	13	14
Other serious medical condition/disability diagnosed by doctor	4.3	5.6	11.3	2.1	2.6	3.2	3.2	2.2	0.6	3.4	3.1	2.3	2.0	1.1	1.1	2.9
Average weekly fortified wine intake	3.9	4.6	11.4	2.0	1.7	2.2	2.5	2.5	2.8	1.7	0.6	2.5	3.4	2.6	0.2	2.2
Frequency of tenseness / restlessness in last 2 weeks	3.5	5.5	12.6	2.4	1.4	2.2	2.1	3.3	3.5	1.6	1.0	3.2	2.7	3.1	-0.8	2.1
Tense / ‘highly strung’	3.4	5.6	23.7	1.7	1.5	1.9	2.5	3.2	2.2	0.4	0.6	2.7	3.0	4.9	-0.5	2.7
Number of treatments/medications taken	3.3	6.0	10.3	2.7	2.2	2.8	2.6	2.6	1.6	2.7	2.4	2.7	3.2	3.1	0.1	2.6
Ever had prostate specific antigen (PSA) test	3.1	3.6	12.3	1.2	2.2	2.0	1.8	2.3	1.0	1.4	1.6	2.0	2.5	3.5	-0.2	1.9
Age when periods started (menarche)	2.9	6.9	16.4	-1.8	-2.3	-4.0	-3.1	-1.8	0.5	-3.8	-3.8	-2.7	-2.5	-0.7	-1.4	-3.6
HDL Cholesterol	2.8	4.7	8.8	-2.6	-1.6	-2.7	-2.3	-2.6	-1.8	-3.0	-2.4	-2.5	-2.2	-2.0	-0.2	-2.0
Suffer from ‘nerves’	2.8	4.4	21.0	2.1	-0.2	1.3	1.1	3.0	2.1	1.2	0.2	2.8	2.5	4.6	-1.5	1.6
Severe depression (siblings)	2.7	3.1	7.2	2.6	0.7	1.5	1.4	2.6	1.4	1.2	0.3	2.2	2.7	2.4	-1.1	1.5
Medication: Lisinopril	2.7	3.5	5.1	2.2	2.1	2.3	2.2	2.1	2.1	1.9	1.7	1.9	1.8	1.8	0.2	2.2
Worrier / anxious feelings	2.6	4.9	23.7	1.8	0.9	1.5	1.3	2.6	4.0	0.6	0.7	2.0	2.3	4.9	-1.4	1.5
Medication: Blood pressure	2.5	4.7	11.5	1.4	2.9	3.4	2.8	1.3	-0.5	2.8	3.2	1.8	1.8	0.3	1.1	2.9
Worry (Nagel 2018)	2.4	5.0	27.1	1.6	0.8	1.4	2.0	2.7	2.7	0.3	0.3	2.0	3.0	5.2	-1.0	2.3
Maternal smoking around birth	2.4	3.4	11.0	0.7	-0.4	-2.2	-2.6	0.2	-0.8	0.3	-3.1	0.9	-1.2	-2.2	-2.8	-3.3
Taking other prescription medications	2.4	3.7	5.5	1.9	2.3	2.2	2.0	2.1	0.8	2.3	2.0	2.2	2.3	2.3	0.4	2.0
Medication: Atenolol	2.3	2.9	7.9	0.7	2.8	2.2	2.7	0.6	0.1	1.1	2.6	0.4	1.2	0.7	1.6	2.7
Number of full brothers	2.3	2.9	9.1	-1.7	-1.0	-2.0	-1.7	-2.1	-1.5	-1.0	-1.5	-1.9	-1.4	-3.0	-0.8	-2.0
Number of self-reported non-cancer illnesses	2.3	4.1	11.6	1.0	2.2	2.7	2.9	0.9	1.0	1.5	3.4	1.1	2.1	1.8	1.3	2.9
Fractured/broken bones in last 5 years	2.3	3.0	8.1	1.8	0.8	1.3	0.9	2.3	1.3	2.3	0.7	2.6	2.9	1.9	-1.8	0.9
Heart attack/myocardial infarction (self-reported)	2.3	2.9	8.3	2.0	2.9	2.1	2.0	1.8	1.1	2.4	1.2	1.9	1.8	0.1	-0.1	1.2
Age at First Birth	2.2	3.2	17.6	1.2	-0.4	1.1	1.1	2.1	3.4	0.3	0.2	1.5	1.3	4.2	-0.1	1.9
Eye problems/disorders: Diabetes related eye disease	2.2	2.4	5.0	-1.0	-1.8	-2.2	-2.0	-1.5	-0.7	-1.0	-1.6	-1.3	-2.0	-1.7	-0.8	-2.2
Pulse wave Arterial Stiffness index	2.2	2.6	5.3	1.7	2.1	2.1	2.3	1.2	1.0	1.4	1.9	1.3	1.8	0.7	0.7	2.3
Illnesses of father: High blood pressure	2.1	2.6	9.5	1.7	0.7	1.5	1.5	2.0	1.3	1.7	0.2	1.7	2.3	3.1	-0.4	1.4
Had other major operations	2.0	2.4	4.8	1.8	1.5	2.2	1.6	1.4	1.0	1.3	1.8	1.4	1.6	1.7	1.0	2.1
Heart attack	2.0	2.5	7.2	1.8	2.7	2.0	2.0	1.7	0.9	2.3	1.2	1.7	1.6	0.2	-0.0	1.1
Pulse wave peak to peak time	2.0	2.3	4.6	-1.7	-2.1	-2.0	-2.1	-1.1	-0.6	-1.3	-1.9	-1.2	-1.7	-0.4	-0.7	-2.1
Age at last live birth	1.9	2.8	21.9	0.9	-0.8	0.5	0.1	2.3	2.3	-0.4	-0.1	1.5	0.7	4.7	-0.9	1.0
Irritability	1.9	3.2	11.6	0.9	0.8	2.0	2.3	2.1	1.8	0.3	1.4	1.3	2.0	3.4	0.5	2.7
Cardiovascular Disease	1.8	5.9	14.0	1.6	3.3	3.4	3.6	1.1	1.2	3.1	3.7	1.0	1.7	0.7	1.8	3.3
Relative age of first facial hair	1.8	3.7	11.2	2.2	-0.5	-2.3	-2.4	0.4	-1.0	0.3	-2.4	0.4	-1.2	-2.2	-3.3	-3.4
Qualifications: CSEs or equivalent	1.8	2.4	6.3	0.4	-1.8	-1.6	-2.3	-0.4	-1.1	0.7	-2.2	0.1	-0.7	-2.3	-1.9	-2.5
Ever highly irritable/argumentative for 2 days	1.8	2.2	4.6	1.9	1.1	1.9	1.4	2.1	0.3	1.3	0.4	2.1	2.1	1.3	-0.4	1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	5.3	1.8	0.2	0.8	0.1	2.3	1.7	0.8	-0.7	1.9	1.2	2.3	-1.8	0.0
Vascular/heart problems diagnosed by doctor	1.8	5.0	11.5	-1.4	-2.7	-3.4	-3.1	-1.6	-0.0	-2.8	-3.3	-1.4	-1.7	-0.6	-1.9	-3.1
Neuroticism (Nagel 2018)	1.7	4.1	21.7	1.2	0.8	1.5	1.8	2.5	2.4	0.6	0.7	2.0	2.5	4.7	-0.6	2.1
Ulcerative Colitis	1.7	2.5	7.9	-2.7	-1.9	-1.5	-0.5	-2.3	-1.0	-2.8	-0.2	-2.3	-1.5	0.1	0.6	-0.1
Neuroticism	1.7	4.1	28.1	0.9	0.1	0.8	0.9	2.7	2.4	0.1	-0.6	2.0	2.3	5.3	-1.8	1.3
Supplements: Glucosamine	1.7	2.3	5.6	2.1	0.7	1.1	0.4	2.4	2.2	0.9	0.2	2.0	2.2	2.0	-1.1	0.7
Medication: Lansoprazole	1.7	1.9	3.7	1.3	1.4	1.6	1.1	1.5	-0.3	1.9	1.3	1.9	1.8	1.8	-1.0	0.8
Ever had bowel cancer screening	1.7	2.0	4.7	0.9	1.6	1.7	2.0	1.3	0.1	2.2	1.7	1.2	1.0	1.4	0.2	2.0
Pain type(s) experienced in last month: Hip pain	1.7	2.2	6.7	-0.1	1.2	1.9	2.4	-0.0	-0.6	1.5	2.6	-0.0	1.1	0.1	1.9	2.4
Alcohol drinker status: Never	1.7	2.1	4.5	1.0	1.6	2.1	1.9	0.9	0.9	1.9	1.9	1.5	1.2	0.5	0.9	2.0
Diabetes (father)	1.6	2.0	5.2	-0.1	-1.6	-2.0	-2.3	-0.1	-1.1	-0.7	-2.2	-0.6	-0.7	1.3	-1.8	-2.1
High blood pressure	1.6	4.3	11.6	0.6	2.5	3.1	3.1	0.8	-0.5	2.2	3.4	0.7	1.1	0.3	2.5	3.1
Fluid intelligence score	1.6	3.4	7.0	0.8	2.2	2.6	2.5	1.3	1.8	0.6	2.4	1.0	1.8	2.0	1.5	2.6
Comparative body size at age 10	1.6	4.4	10.6	0.9	2.8	3.1	3.2	0.5	-0.5	2.0	3.0	1.2	2.3	-0.0	1.8	3.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.1	8.9	1.9	0.1	0.7	1.0	1.8	0.3	0.1	0.1	2.0	2.4	3.0	-1.4	0.8
Medication for cholesterol	1.6	2.5	8.0	-1.1	-2.0	-2.1	-1.9	-0.5	0.5	-2.6	-2.8	-0.8	-1.2	0.2	-0.7	-1.8
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.5	8.4	-2.6	-0.1	-0.5	1.3	-2.9	-0.2	-1.7	1.8	-2.5	-1.9	-2.4	2.8	1.0
Serious illness, injury or assault to yourself	1.5	1.8	4.2	1.2	2.0	1.7	2.1	1.4	-0.6	1.7	1.0	1.1	1.4	0.0	0.7	1.5
Hypothyroidism/myxoedema (self-reported)	1.5	3.0	5.4	1.2	1.6	2.1	1.6	1.9	0.3	2.3	2.3	2.3	1.9	2.1	-0.4	1.8
Medication for pain relief, constipation, heartburn	1.5	2.6	5.5	-2.1	-1.4	-1.8	-1.7	-2.0	-0.6	-1.1	-0.9	-2.1	-2.3	-2.1	-0.2	-1.6
Commuting to job workplace: Walk	1.5	1.7	5.8	0.1	-1.3	-1.5	-1.6	0.5	1.6	-1.7	-2.4	-0.4	-0.7	0.1	-1.1	-1.9
Medication: Paracetamol	1.5	2.3	5.7	2.0	1.3	2.0	1.9	1.4	0.2	1.6	1.5	1.6	2.4	1.2	0.3	1.6
Mean Putamen Volume	1.4	1.7	3.1	-1.5	-1.7	-1.8	-1.6	-1.2	0.0	-1.8	-1.5	-1.3	-1.3	0.1	-0.4	-1.4
Chronotype (morning person)	1.4	3.3	7.6	1.8	2.4	2.7	2.3	1.0	0.2	2.4	2.5	0.8	1.2	1.0	1.2	2.6
Sensitivity / hurt feelings	1.4	2.5	11.6	1.2	-0.6	0.1	-0.4	1.9	2.5	0.5	-1.0	1.9	1.6	3.4	-1.8	-0.0
High blood pressure (mother)	1.4	2.0	7.3	-0.4	0.6	1.9	1.9	0.3	1.1	-0.3	2.6	0.5	1.3	1.2	1.2	2.7
Hearing difficulty/problems with background noise	1.4	2.2	6.6	1.9	1.5	1.4	1.1	2.4	-0.8	2.0	0.1	2.6	1.8	0.6	-0.8	0.9
Headache pain in last month	1.4	2.4	6.7	0.5	2.3	2.3	2.6	0.8	0.3	1.3	1.5	1.1	1.8	0.7	1.2	2.3
Medication: Ibuprofen	1.4	1.6	7.3	-0.0	-1.8	-1.3	-1.3	0.6	1.1	-0.8	-1.4	0.5	0.5	2.7	-1.7	-1.0
Hypertension (Self-reported)	1.4	3.9	10.2	0.4	2.6	3.0	2.8	0.5	-0.2	2.4	3.2	0.6	0.7	-0.1	2.4	3.0
Average weekly beer plus cider intake	1.4	2.0	4.9	-0.4	-1.9	-1.5	-2.1	-0.2	-0.7	-0.2	-1.8	0.1	-1.3	-2.2	-1.6	-2.2
Medication: Co-codamol	1.3	1.6	3.5	1.1	1.0	1.6	1.3	1.3	0.5	1.2	1.3	1.9	1.8	1.4	-0.4	1.3
Relative age voice broke	1.3	1.9	4.7	-0.4	-0.4	-2.1	-1.4	-0.9	-1.5	-1.0	-1.9	-1.1	-1.5	-2.2	-0.7	-2.1
Neuroticism score	1.3	2.8	15.5	0.9	-0.1	0.5	0.6	2.4	2.3	-0.5	-0.8	1.8	1.8	3.9	-1.7	0.9
Hair/balding pattern: Pattern 4	1.3	3.2	6.8	2.5	1.8	2.4	1.6	2.5	1.0	1.9	1.5	2.6	1.8	1.2	-0.7	1.5
Commuting to job workplace: Car/motor vehicle	1.3	1.5	4.2	0.2	1.3	1.9	1.7	-0.2	-0.1	1.1	2.1	0.2	0.2	-1.1	1.6	1.8
Supplements: Vitamin C	1.3	1.5	3.8	1.9	1.1	1.0	1.2	1.3	1.0	1.8	0.2	1.2	2.0	1.2	-1.0	0.6
Guilty feelings	1.3	1.9	6.3	1.6	0.8	0.7	-0.3	2.5	0.9	0.6	-1.2	2.4	1.6	1.3	-2.0	-0.3
Eye problems/disorders: Glaucoma	1.3	1.6	4.0	-0.8	1.2	1.3	1.6	-0.7	-2.0	0.5	1.6	-0.4	1.1	-0.6	2.0	1.7
Ever depressed for a whole week	1.3	1.6	7.8	1.5	-0.2	0.8	1.0	1.4	-0.1	0.3	-0.1	1.4	2.2	2.8	-1.2	0.9
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	4.4	0.4	0.9	1.7	1.9	0.5	0.2	0.3	2.0	0.6	1.4	0.8	1.7	2.1
Lung FEV1/FVC ratio	1.2	6.0	14.7	1.9	3.8	3.3	3.3	1.9	2.4	2.5	2.5	2.2	2.2	1.4	1.2	2.9
Prospective memory result	1.2	1.5	7.0	-0.4	-0.6	-1.1	-1.0	-1.0	-2.1	0.4	-0.9	-0.8	-1.1	-2.7	-0.5	-1.6
Breastfed as a baby	1.2	1.5	4.5	1.4	1.3	1.4	1.1	1.4	0.5	2.1	1.6	0.8	1.3	1.2	-0.4	1.2
Neck or shoulder pain in last month	1.2	1.7	4.6	1.4	0.3	0.8	0.5	1.9	1.4	0.3	-0.9	2.0	2.0	2.1	-1.2	0.7
Ever taken oral contraceptive pill	1.2	1.3	3.9	-1.4	-1.1	-1.4	-1.3	-1.4	0.6	-2.0	-0.9	-1.3	-1.4	-0.7	0.1	-0.8
Crohns Disease (2012)	1.1	1.8	5.4	-0.1	1.2	1.9	2.1	-0.0	0.1	0.3	1.8	0.7	1.6	1.3	1.4	2.3
Heel T-Score	1.1	8.4	27.2	-4.0	-1.1	-2.2	-1.1	-4.6	-2.0	-2.3	-0.4	-4.2	-3.6	-5.2	1.9	-1.5
Stomach or abdominal pain in last month	1.1	1.3	4.3	1.3	0.5	0.9	0.6	1.8	0.6	0.9	0.3	1.8	1.5	2.1	-0.7	0.6
Medication: Levothyroxine sodium	1.1	1.8	4.8	0.7	1.6	1.7	1.4	1.1	-0.7	2.2	1.8	1.5	1.6	0.8	-0.1	1.4
Nervous feelings	1.1	2.0	13.5	0.4	-0.8	0.4	1.2	1.6	2.1	-0.8	-0.3	0.7	1.2	3.7	-0.5	1.5
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.4	6.2	-2.3	-1.1	-1.1	0.3	-2.5	-0.4	-2.1	0.8	-2.4	-1.8	-1.9	1.7	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	9.2	0.9	-0.4	0.6	0.6	1.4	1.8	0.0	0.1	1.5	1.8	3.0	-1.0	0.9
Knee pain experienced in last month	1.1	1.8	6.8	1.2	-0.9	0.1	-0.2	1.9	1.4	0.7	-0.7	1.9	1.5	2.6	-1.8	-0.1
Mineral and other dietary supplements	1.1	1.4	3.4	-1.6	-1.6	-0.9	-1.0	-1.4	-1.9	-0.4	0.1	-1.1	-1.3	-1.8	0.8	-0.7
Supplements: Calcium	1.1	1.2	4.8	0.6	0.7	1.0	1.4	0.9	1.9	0.2	0.3	0.5	1.3	2.2	0.1	1.2
Ulcerative Colitis (UC)	1.0	2.0	5.8	-2.2	-1.3	-0.9	0.3	-2.1	-0.9	-2.4	0.5	-2.3	-1.0	0.4	1.4	0.5
Major Depression (MDD)	1.0	1.3	6.4	0.8	-0.5	0.4	0.1	1.3	-0.6	0.5	-0.7	1.4	1.3	2.5	-1.8	0.5
Hypothyroidism (self reported)	1.0	2.3	5.0	0.4	1.4	2.1	1.6	1.3	0.8	1.5	2.2	1.5	1.6	2.1	0.5	2.1
Frequency of depressed mood in last 2 weeks	1.0	1.4	5.8	1.2	1.2	0.9	0.9	1.9	1.3	0.7	-0.4	2.4	1.4	0.8	-0.9	0.8
Hair/balding pattern: Pattern 2	1.0	1.3	4.6	-1.5	-1.3	-1.0	-0.5	-1.6	0.1	-2.2	-0.9	-1.8	-0.7	0.1	1.1	-0.5
Length of working week for main job	1.0	1.1	2.9	-0.7	-1.2	-1.7	-1.4	-0.8	-0.3	-0.8	-0.9	-1.1	-1.5	-1.0	-0.7	-1.3
Medication: Paracetamol	1.0	1.6	4.9	1.9	1.5	1.6	1.4	1.1	0.4	1.2	1.1	1.3	2.2	0.5	0.2	1.1
Gout (self-reported)	1.0	1.4	7.2	-1.3	-0.2	-0.2	-0.2	-1.2	-2.7	0.6	0.9	-0.7	-0.9	-2.3	1.1	-0.5
Birth weight	1.0	2.2	6.6	0.5	1.4	1.7	2.6	-0.3	-0.1	1.6	2.6	-0.1	1.1	-0.5	2.1	2.0
Shortness of breath walking on level ground	1.0	1.2	3.4	1.5	1.0	-0.3	-0.5	1.2	0.0	1.6	-0.6	1.2	0.7	-1.2	-1.8	-1.3
Medication: Omeprazole	1.0	1.2	3.0	0.7	0.7	1.4	1.5	0.7	0.3	0.1	1.6	0.8	1.6	1.0	1.1	1.7
Medication: Aspirin	1.0	1.4	4.6	1.6	0.8	1.0	0.7	2.1	0.1	0.7	-0.5	1.9	1.0	1.9	-0.6	0.7
Long-standing illness, disability or infirmity	1.0	1.5	4.1	1.6	0.2	0.9	0.9	2.0	0.9	1.4	0.3	1.8	1.9	1.5	-0.7	1.0
Diastolic blood pressure, automated reading	1.0	3.2	8.0	1.1	2.8	2.7	2.1	1.0	-1.0	2.3	2.5	1.0	0.6	-1.1	1.6	2.1
Alcohol drinker status: Previous	1.0	1.1	4.8	0.2	-1.7	-1.1	-1.7	0.4	-0.5	-1.2	-2.2	-0.0	-0.4	0.6	-0.4	-1.1
Vitamin and mineral supplements	0.9	1.3	2.5	-1.1	-1.2	-1.5	-1.6	-0.8	-1.4	-1.0	-0.9	-0.9	-1.3	-1.1	-0.5	-1.6
Pulse wave reflection index	0.9	1.1	3.2	1.1	1.6	1.4	1.0	1.0	1.1	0.8	0.8	1.1	1.8	0.1	0.2	1.1
Age at first live birth	0.9	1.6	9.8	-0.0	-1.7	-0.6	-0.8	1.1	1.8	-1.5	-0.7	0.6	-0.5	3.1	-0.8	0.1
Heart disease (mother)	0.9	1.1	2.9	1.1	-0.9	-0.3	-0.7	1.7	1.3	-0.0	-1.7	1.1	1.4	-0.1	-1.5	-0.8
Alcohol intake frequency.	0.9	2.1	7.2	0.2	1.3	1.9	2.1	-0.1	0.1	0.6	1.8	0.2	1.0	2.1	1.9	2.7
Friendships satisfaction	0.9	1.1	3.8	-0.6	-1.7	-1.1	-0.7	0.2	-0.0	-1.3	-1.4	0.4	0.2	1.9	-1.9	-0.3
Wears glasses or contact lenses	0.9	1.1	3.6	1.9	0.4	1.2	0.5	1.4	-1.1	1.5	0.8	1.6	0.6	0.6	-0.4	0.5
Commuting to job workplace: Public transport	0.9	1.1	2.8	1.7	1.0	0.4	0.2	1.6	0.7	0.9	-0.5	1.5	1.3	1.4	-1.0	0.0
Cholesterol lowering medication	0.9	1.3	4.3	1.1	1.0	1.5	1.3	0.6	0.3	2.1	1.9	1.0	1.1	0.5	-0.4	1.0
Breast Cancer	0.8	1.9	5.4	0.3	-1.1	-1.7	-2.3	0.1	-1.2	0.0	-2.3	0.1	-1.2	-1.1	-1.5	-2.2
Ovarian Cancer	0.8	1.1	3.4	0.7	-1.3	-0.9	-1.3	1.1	0.0	0.3	-1.4	0.7	0.4	1.4	-1.8	-1.2
Systolic Blood Pressure	0.8	4.2	12.2	0.4	2.5	3.3	3.0	1.2	1.5	1.3	2.9	0.8	1.6	0.7	1.8	3.5
Hearing difficulty/problems: Yes	0.8	1.3	4.0	1.7	1.3	1.0	1.0	1.3	-0.9	2.0	0.4	1.8	0.9	0.3	-0.4	0.6
Systolic blood pressure, automated reading	0.8	2.3	6.3	0.3	1.9	2.5	2.1	0.7	-0.4	1.5	2.1	0.5	0.5	-0.5	1.8	2.5
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	5.2	0.1	-0.5	0.5	1.0	0.6	1.7	-0.0	0.7	0.2	0.5	2.3	-0.4	1.3
Chronic bronchitis/emphysema (father)	0.8	0.9	4.5	0.5	-0.2	-0.4	-1.3	0.4	0.0	0.6	-0.9	1.0	-0.6	-1.4	-2.1	-1.4
Time employed in main current job	0.8	0.9	3.1	1.1	0.7	0.8	0.9	1.0	-0.3	1.1	0.2	1.8	1.3	0.9	-1.0	0.5
Illnesses of mother	0.8	0.9	3.8	-0.4	0.1	-0.6	-0.3	-1.4	-1.0	0.5	0.6	-1.1	-2.0	-1.4	1.3	-0.6
Glaucoma (self-reported)	0.8	0.9	2.3	-0.3	1.5	1.1	1.2	0.0	-1.5	0.5	0.9	0.5	1.4	-0.5	0.9	1.2
Medication: Ventolin 100micrograms inhaler	0.8	1.0	2.6	-0.4	1.6	1.0	1.4	-0.6	-1.4	-0.3	1.3	-0.5	0.3	-1.0	1.6	0.9
Health satisfaction	0.8	1.1	3.7	-0.6	-1.9	-1.6	-1.1	0.0	-0.7	-1.2	-1.4	-0.0	-0.5	0.8	-1.1	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	3.3	0.4	1.0	1.2	1.8	0.1	0.4	-0.1	1.0	0.4	1.1	1.5	0.3	1.4
Illnesses of father: Heart disease	0.8	1.1	3.1	1.8	-0.1	0.6	0.0	1.4	1.0	1.2	-0.4	1.2	1.4	1.1	-1.6	-0.2
Eye problems/disorders: Cataract	0.8	0.9	3.0	0.9	0.3	0.8	0.5	1.4	0.2	1.7	0.5	1.7	1.5	0.4	-1.0	0.3
Hearing aid user	0.8	0.9	4.1	0.6	0.9	1.1	1.0	-0.0	-2.0	1.6	0.8	0.5	0.6	-1.2	0.4	0.6
Supplements: Fish oil (including cod liver oil)	0.8	1.1	3.4	1.8	1.4	1.1	0.9	1.3	1.6	0.6	0.0	1.1	1.0	0.7	-0.2	0.7
High cholesterol (Self-reported)	0.8	1.3	4.9	0.8	0.9	1.4	1.5	0.6	0.6	2.2	2.1	0.6	0.8	0.7	0.4	1.2
Unable to work because of sickness or disability	0.8	1.0	2.8	1.4	0.9	0.9	0.9	1.3	1.5	0.8	-0.2	1.3	1.7	0.3	-0.6	0.7
Prostate Cancer	0.7	1.0	3.1	-0.9	1.1	0.3	0.7	-0.8	1.6	0.4	0.6	-0.6	-1.1	-1.7	1.6	0.5
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.4	0.9	-1.4	-0.8	-1.1	0.3	-1.5	-0.3	-0.5	0.5	0.1	1.0	-1.3	-1.2
Supplements: Zinc	0.7	0.8	3.3	0.6	0.1	-0.6	-0.5	0.7	1.1	-0.7	-1.4	0.4	1.0	1.8	-1.1	-0.6
Diabetes (mother)	0.7	0.8	2.2	-0.4	-0.8	-1.1	-1.2	0.0	1.5	-1.1	-1.3	-0.2	-0.1	-0.4	-1.4	-1.0
Alcohol usually taken with meals	0.7	1.1	4.4	-0.4	2.1	1.0	1.2	-0.4	-0.5	-0.7	0.8	0.0	0.5	0.1	1.9	1.6
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	3.7	1.3	0.8	0.8	0.7	1.6	0.7	0.3	-0.3	1.5	1.9	1.1	-0.8	0.7
Loud music exposure frequency	0.7	0.8	1.6	0.9	0.7	0.9	1.1	0.8	-1.0	1.0	0.9	0.3	1.0	1.3	0.3	1.0
Chronic bronchitis/emphysema (mother)	0.7	0.8	5.2	-1.0	-0.6	-0.5	-0.3	-0.8	-2.3	0.1	0.1	-0.2	0.3	-1.9	-0.1	-0.6
Exposure to tobacco smoke outside home	0.7	1.0	3.3	0.8	-1.5	-0.9	-0.9	0.8	0.5	-0.2	-1.8	0.5	0.8	-0.7	-1.3	-1.2
Worry too long after embarrassment	0.7	1.2	7.1	0.4	-0.5	-0.0	-0.2	1.0	2.7	-1.0	-0.2	0.5	0.2	2.5	-0.7	0.4
Medication: Allopurinol	0.7	1.0	6.7	-0.7	-0.9	-0.7	-1.1	-0.3	-2.6	0.7	-0.3	0.3	-1.0	-0.9	-0.5	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.7	-1.0	0.4	-0.9	-0.8	-1.2	-0.6	-1.1	-0.7	-1.0	-0.3	-1.6	-0.1	-1.2
Tinnitus: Yes, now most or all of the time	0.7	0.8	4.2	0.7	1.3	1.0	0.8	0.8	-1.0	0.4	-0.2	0.9	2.0	-0.1	0.2	0.7
Pain experienced in last month	0.7	1.2	4.9	-0.5	-0.5	-0.7	-0.8	-1.5	-1.4	-0.5	0.2	-1.3	-1.6	-2.2	0.7	-0.7
Crohns Disease (2017)	0.6	1.3	3.8	0.2	1.3	1.6	1.7	0.1	-0.6	0.2	1.7	0.8	1.9	0.8	0.7	1.6
Irritable Bowel Disease (IBD)	0.6	1.3	3.1	-1.2	0.1	0.7	1.5	-1.2	-0.9	-1.4	1.8	-0.9	0.7	0.7	1.6	1.7
Verbal and Numeric Reasoning (VNR)	0.6	1.5	4.6	-1.7	-0.0	-0.5	0.1	-1.7	-1.2	-1.8	0.3	-2.1	-0.7	-1.3	1.8	0.3
Smoking Status	0.6	1.4	4.5	1.0	-0.1	-1.5	-1.6	0.5	-0.5	0.2	-2.1	0.2	-0.9	-1.0	-1.6	-2.1
Townsend deprivation index at recruitment	0.6	0.9	2.7	-0.1	0.7	0.8	1.6	-0.9	-1.4	-0.0	1.1	-0.2	-0.1	-1.5	1.3	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.7	2.1	0.4	0.9	0.6	0.9	0.9	1.2	-0.2	-0.1	1.4	0.8	1.3	-0.7	1.0
Multivitamins +/- minerals	0.6	0.7	1.4	0.7	0.8	1.1	1.0	0.7	0.4	1.0	0.7	0.9	1.2	1.1	0.4	1.1
Past tobacco smoking	0.6	1.1	3.7	0.4	0.0	1.6	1.4	0.1	0.9	0.3	1.9	0.5	1.2	0.6	1.1	1.8
Had menopause	0.6	0.7	2.0	1.1	0.4	0.9	0.8	1.1	0.4	0.5	0.2	1.4	0.9	1.2	-0.5	0.9
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.5	-0.6	-1.2	-1.0	-0.7	-0.7	0.9	-1.6	-0.1	-1.1	-0.7	1.4	-0.3	-0.2
Father’s age at death	0.6	0.8	4.4	0.9	-0.3	-0.5	-0.8	1.1	-1.1	0.1	-1.0	0.5	0.3	2.1	-0.7	-0.7
Falls in the last year	0.6	0.8	3.8	0.3	0.1	0.5	0.9	1.0	2.0	0.1	0.5	1.1	0.3	1.6	-0.7	0.7
Hair/balding pattern: Pattern 3	0.6	0.8	3.0	-1.3	-0.2	-1.2	-0.5	-1.2	-0.1	-1.1	-0.3	-1.7	-1.5	-0.0	-0.0	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	3.9	0.2	-0.6	-0.9	-0.9	0.5	0.8	-0.4	-1.0	0.5	0.7	2.0	-1.1	-0.8
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.2	0.6	-0.6	-0.7	-0.8	0.1	-1.5	-0.4	-1.2	0.1	-0.9	-1.1	-1.1	-1.1
Medication: Blood pressure	0.6	1.0	3.9	0.3	0.6	0.9	1.3	0.8	1.5	0.6	1.1	0.3	0.1	2.0	0.9	1.3
Migraine (self-reported)	0.6	0.8	3.8	-1.1	-0.2	-0.2	-0.4	-0.9	-1.4	-1.9	0.1	-0.8	-0.8	-0.0	1.1	0.3
Medication: Aspirin	0.6	0.8	3.3	1.2	0.4	0.6	0.4	1.4	-0.5	0.5	-0.5	1.4	0.4	1.8	-0.5	0.5
Mother’s age at death	0.6	0.8	1.9	-1.1	0.1	0.1	0.3	-1.4	-1.2	-1.2	0.7	-1.0	-0.6	-0.8	1.2	0.7
Ever smoked	0.6	1.0	3.4	-0.7	-0.7	-1.6	-1.4	-0.3	-0.5	-0.3	-1.9	-0.7	-1.5	-0.4	-0.5	-1.3
Heart disease (siblings)	0.6	0.7	3.1	0.4	-0.4	-0.6	-0.7	0.4	-0.6	0.1	-1.7	0.6	0.8	0.6	-1.8	-1.0
Depression (Nagel 2018)	0.5	0.8	2.3	0.6	0.6	0.2	0.5	1.3	1.2	0.4	-0.5	1.5	1.1	1.4	-0.8	0.6
Neuroticism (2016)	0.5	0.7	4.4	0.1	0.0	0.5	0.7	1.0	0.3	-0.2	-0.2	0.4	1.1	2.1	0.8	0.9
Triglycerides	0.5	0.9	3.8	1.4	-0.2	0.6	0.1	1.5	0.8	1.1	0.3	1.0	0.4	1.9	-0.8	0.4
Angina	0.5	0.6	1.9	0.1	1.4	1.3	1.2	0.2	0.5	-0.0	1.0	0.4	0.6	0.2	0.6	1.3
Medication for hormone replacement therapy	0.5	0.6	2.2	-0.3	0.9	0.1	0.6	-0.5	-0.6	-0.0	0.8	-1.0	0.0	-1.4	1.5	0.3
Fed-up feelings	0.5	0.9	3.3	-1.6	-1.1	-0.9	-0.6	-0.5	-0.2	-1.8	-1.1	-0.5	-1.2	0.8	-0.5	-0.4
Number of incorrect matches in round	0.5	0.9	5.6	0.9	-0.1	0.6	0.8	0.1	-2.4	1.6	0.7	0.8	0.7	0.9	-0.6	0.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	3.3	0.7	-0.4	0.4	1.0	0.5	-1.0	-0.1	-0.2	0.2	1.8	1.4	-0.5	0.7
Qualifications: None of the above	0.5	1.1	2.5	0.5	1.5	1.2	1.6	0.1	-1.0	0.6	1.5	0.2	0.2	-1.1	1.3	1.4
Mouth/teeth dental problems	0.5	0.8	3.4	-1.8	-1.0	-0.4	-0.0	-1.5	0.6	-1.3	0.4	-0.8	-0.2	1.2	0.5	0.3
Pain all over the body in last month	0.5	0.5	1.7	0.2	-0.6	-0.5	-1.1	0.9	0.5	0.1	-1.3	0.5	0.2	0.5	-1.2	-0.9
Mouth/teeth dental problems: Dentures	0.5	0.9	4.3	2.1	0.4	0.4	-0.3	1.7	-0.4	0.8	-0.9	1.2	0.9	-0.1	-0.8	-0.4
Lung cancer (father)	0.5	0.6	5.2	0.0	-0.2	0.1	-0.1	-0.2	-1.0	1.1	-0.2	0.1	-0.7	-2.3	-0.6	-0.6
Wheeze or whistling in the chest in last year	0.5	0.9	2.3	-0.3	-1.4	-1.4	-1.1	-0.3	-0.9	-0.4	-1.5	-0.2	-0.6	-1.0	-0.8	-1.2
Angina (self-reported)	0.5	0.6	2.0	0.2	1.4	1.3	1.2	0.6	0.5	0.2	0.8	0.7	0.7	0.3	0.3	1.1
Medication: Seretide 50 evohaler	0.5	0.6	2.7	0.6	-0.5	-0.9	-1.0	0.5	0.3	-0.1	-0.8	0.3	0.2	-0.1	-1.6	-1.4
Comparative height size at age 10	0.5	2.8	7.1	0.1	1.9	2.3	2.7	0.3	0.8	1.8	2.4	0.7	1.5	0.9	1.8	2.6
Mood swings	0.5	0.9	2.4	0.3	0.8	1.2	1.1	1.4	0.4	0.2	0.1	1.5	1.1	1.6	-0.7	1.1
Qualifications: nursing, teaching	0.5	0.8	3.4	0.8	0.9	1.2	0.6	0.7	1.8	0.3	0.9	0.5	0.7	1.4	0.8	0.7
Asthma (self-reported)	0.5	1.0	2.7	-0.2	0.9	1.6	1.5	-0.3	-0.4	0.3	1.5	0.3	1.6	-0.3	1.0	1.4
Illnesses of father: None of the above (group 1)	0.5	0.6	1.3	-1.1	-0.3	-0.3	-0.1	-1.1	-1.1	-1.2	0.5	-0.9	-0.8	-0.3	1.0	0.3
Financial situation satisfaction	0.5	0.6	2.1	0.3	0.7	0.6	0.9	0.1	0.1	-0.8	1.1	0.5	1.2	1.4	-0.0	0.9
Alzheimer’s Disease (in father)	0.4	0.4	1.0	-0.5	-0.5	-0.8	-0.6	-0.0	0.8	-1.0	-0.9	0.3	0.4	-0.6	-0.7	-1.0
Body Mass Index (BMI) (2010)	0.4	0.6	4.3	0.9	-0.2	0.4	0.1	0.9	-0.6	0.8	0.3	0.7	0.4	2.1	-0.6	0.1
Coronary Artery Disease (CAD)	0.4	0.5	4.8	-0.1	0.0	0.4	0.5	-0.2	0.6	-0.6	0.2	-0.5	0.3	2.2	-0.1	0.5
Current tobacco smoking	0.4	0.7	2.1	0.2	-0.9	-0.8	-1.1	-0.0	1.0	-0.2	-1.0	-0.1	-1.1	-1.5	-0.2	-1.1
Body mass index (BMI)	0.4	1.6	6.4	0.8	1.1	0.6	0.1	0.3	-2.4	2.1	0.7	1.2	0.3	-2.5	-0.7	-0.4
Waist circumference	0.4	1.6	7.4	1.1	1.5	0.8	0.3	0.8	-1.6	2.7	0.9	1.5	0.3	-2.1	-0.5	-0.1
Medication: Ramipril	0.4	0.5	1.5	1.2	1.0	0.5	0.6	0.9	-0.1	0.7	-0.1	0.6	1.1	0.9	-0.2	0.2
Medication: Simvastatin	0.4	0.6	2.7	0.9	0.2	0.7	0.5	0.6	-0.2	1.6	1.4	0.2	0.4	0.8	0.1	0.5
Arm fat percentage (right)	0.4	1.5	10.3	0.4	0.4	0.4	-0.2	-0.2	-2.4	1.7	0.8	0.9	0.1	-3.2	-0.2	-0.4
Hip circumference	0.4	1.8	5.9	1.6	1.5	0.9	-0.1	1.5	-1.2	2.4	0.5	1.9	1.5	-0.8	-1.6	-0.4
Happiness	0.4	0.5	1.4	-0.5	-0.7	0.4	0.9	0.5	0.1	-0.9	0.7	0.6	0.7	1.1	0.3	1.2
Asthma	0.4	0.8	2.3	-0.1	0.9	1.4	1.3	-0.2	-0.8	0.2	1.2	0.3	1.5	-0.6	0.9	1.1
Blood clot in the leg (DVT)	0.4	0.5	2.0	0.5	-0.1	-0.1	-0.8	0.2	-1.4	0.2	-0.4	0.9	0.4	-1.1	-1.3	-0.7
Medication: Amlodipine	0.4	0.5	2.3	-0.1	1.1	0.7	0.7	-0.1	-0.8	1.5	1.2	0.1	0.1	0.2	0.3	0.6
Number of children fathered	0.4	0.4	1.5	0.8	1.0	0.3	0.0	0.6	0.3	1.2	0.8	0.2	0.0	1.0	-0.7	-0.1
Emphysema/chronic bronchitis	0.4	0.5	2.1	-0.7	-1.5	-1.0	-0.5	-0.5	-0.5	-0.8	-0.8	-0.2	-0.6	-0.9	-0.2	-0.4
Family relationship satisfaction	0.4	0.5	1.6	0.2	0.2	0.0	0.0	0.8	-0.3	-0.7	-0.9	1.2	1.2	1.0	-1.3	0.2
Illnesses of siblings: Diabetes	0.4	0.5	3.8	-0.2	0.3	-0.4	0.4	-0.0	0.3	-0.5	-0.5	-0.3	1.2	1.9	-0.8	-0.1
Smoking status: Previous	0.4	0.7	1.7	-0.7	0.1	-1.2	-0.8	-0.1	-1.3	-0.7	-1.3	-0.6	-0.7	0.4	-0.7	-1.1
Arm fat percentage (left)	0.4	1.5	9.1	0.6	0.7	0.6	0.0	0.0	-2.1	1.8	0.8	1.1	0.3	-3.0	-0.3	-0.2
Loneliness, isolation	0.4	0.6	2.2	0.4	0.1	0.1	0.4	0.9	1.0	-0.4	-0.7	1.1	0.3	1.5	-1.3	0.4
Back pain experienced in last month	0.4	0.5	3.7	0.2	-0.7	-0.2	-0.2	0.4	1.9	-0.3	-0.6	1.0	0.0	0.7	-1.2	-0.2
Medication: Gliclazide	0.4	0.4	0.9	0.7	1.0	-0.3	0.0	0.9	0.1	0.9	-0.8	0.5	0.4	-0.4	-0.9	-0.8
Smoking status: Current	0.4	0.7	1.8	0.6	-0.7	-0.8	-1.1	0.1	1.1	0.1	-1.0	0.2	-1.1	-1.4	-0.5	-1.1
Average weekly champagne plus white wine intake	0.4	0.6	3.4	0.8	-0.7	-0.4	-0.4	1.0	1.9	-0.6	-0.9	0.7	0.6	0.3	-0.7	-0.5
Medication: Bendroflumethiazide	0.4	0.5	1.6	0.7	1.0	0.9	0.4	0.9	1.3	0.8	0.3	0.8	-0.8	0.6	0.2	0.6
Number of operations (self-reported)	0.4	0.5	1.3	-0.8	0.4	0.7	0.8	-0.9	0.1	-0.1	1.0	-0.6	-0.6	-1.0	1.1	1.0
Risk taking	0.4	0.5	2.5	0.1	1.4	0.1	0.1	0.7	1.3	0.3	-0.4	0.6	-0.2	-1.6	-0.6	-0.2
Age started oral contraceptive pill	0.4	0.6	1.1	1.0	-0.9	-0.1	-0.2	1.0	0.3	0.7	-0.9	0.8	0.7	1.0	-1.1	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.5	0.3	-0.2	-0.2	-0.9	0.2	-1.6	-0.2	-0.5	0.8	0.5	-0.9	-1.3	-0.7
Bipolar Disorder (2018)	0.3	0.4	4.3	0.1	-0.8	0.1	0.2	0.2	2.1	-0.7	0.1	0.4	-0.0	-0.1	-0.2	0.5
Depressed Affect (Nagel 2018)	0.3	0.6	4.6	-0.2	0.3	0.4	0.6	0.8	0.7	0.0	0.0	0.8	0.7	2.1	-0.8	0.7
Schizophrenia (2018)	0.3	0.7	4.5	0.4	2.1	0.6	0.7	0.2	0.5	0.6	-0.1	0.7	1.5	-0.7	-0.7	0.2
Alzheimer’s Disease (in mother)	0.3	0.4	0.8	0.6	-0.1	0.3	0.3	0.5	-0.8	-0.6	-0.8	0.9	0.6	0.8	-0.8	0.3
Alzheimer’s Disease (including proxy)	0.3	0.4	1.2	0.1	0.2	0.8	1.0	0.2	0.2	-0.4	0.2	1.0	1.1	0.1	0.2	1.0
LDL Cholesterol	0.3	0.5	2.1	0.4	0.7	-0.0	-0.6	-0.1	-0.0	0.9	-0.1	0.7	-0.6	-1.5	-0.8	-1.0
Lupus	0.3	0.4	1.1	0.7	-0.2	0.9	1.0	0.3	-0.5	0.1	0.4	0.7	0.9	-0.5	0.2	1.0
Blood Platelet Count	0.3	3.8	10.2	0.5	3.2	2.1	3.0	-0.5	-0.4	1.0	3.1	-0.1	1.2	-1.5	2.8	2.5
Blood Red Count	0.3	3.0	12.4	0.5	-2.2	-1.4	-2.4	1.1	-0.0	-0.2	-1.7	0.7	0.5	2.8	-3.5	-2.0
BMI	0.3	2.0	7.6	0.6	2.2	1.5	1.1	0.1	-1.6	2.8	2.2	1.0	0.1	-1.6	0.5	0.7
Ever had hysterectomy (womb removed)	0.3	0.3	1.2	0.8	0.4	0.4	0.2	0.6	-0.3	0.9	-0.7	1.1	0.5	0.2	-0.8	0.1
Medication: Metformin	0.3	0.4	2.2	0.8	1.5	0.1	0.1	0.5	-0.6	1.2	-0.1	0.3	0.5	0.1	-0.5	-0.3
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.7	-0.5	-0.5	-0.4	-0.7	-0.1	-0.4	0.2	-1.3	0.1	-0.8	-0.6	-0.4	-0.3
Sitting height	0.3	1.9	4.5	1.8	0.3	1.0	0.4	2.1	1.8	2.0	-0.4	1.6	1.9	1.8	-1.2	0.3
Forced vital capacity (FVC)	0.3	1.1	4.7	-2.2	-0.6	-0.4	-0.1	-1.6	-0.3	-1.6	0.1	-1.9	0.4	-0.1	0.7	0.2
Alcohol intake versus 10 years previously	0.3	0.5	1.1	-0.8	-1.0	-0.8	-0.7	-0.9	-0.4	-0.3	0.3	-0.8	-1.1	1.0	-0.4	-0.4
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	3.8	-2.0	-0.2	-0.4	0.0	-1.5	-0.1	-1.6	0.3	-1.9	0.4	0.1	0.4	0.3
Pulse rate	0.3	0.4	3.4	-0.4	0.8	-0.4	-0.1	-0.8	-1.8	0.1	0.1	-0.9	-0.5	-0.2	0.2	-0.2
Arm fat mass (right)	0.3	1.3	6.5	0.5	1.1	0.8	0.3	0.1	-1.8	1.9	1.0	0.9	0.2	-2.6	0.0	0.0
Standing height	0.3	2.6	8.0	0.6	1.2	1.6	2.0	1.0	2.8	0.8	1.2	0.2	1.8	2.7	1.4	2.2
Exposure to tobacco smoke at home	0.3	0.3	1.0	0.4	-0.2	0.6	0.6	0.0	0.6	0.8	0.2	0.1	-0.5	0.5	0.8	1.0
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	2.2	-0.9	-0.6	-0.5	-0.7	-1.2	-0.4	-1.1	-0.5	-0.5	-0.4	-1.5	0.2	-0.5
High blood pressure (siblings)	0.3	0.4	1.6	0.7	0.2	0.3	0.3	1.0	0.6	0.6	-0.2	0.8	1.3	1.0	-0.8	0.3
Body fat percentage	0.3	1.1	6.1	0.7	0.9	0.7	0.2	0.4	-1.5	1.6	0.9	1.2	0.5	-2.5	-0.2	-0.0
Leg fat percentage (right)	0.3	1.1	4.2	1.1	0.3	0.3	-0.3	0.7	-1.5	1.8	0.2	1.6	0.3	-2.0	-1.1	-0.5
Arm fat-free mass (right)	0.3	1.4	4.3	0.5	1.8	1.5	1.7	0.3	0.6	2.1	1.6	0.2	0.6	0.4	1.0	1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.0	-1.0	-0.7	0.0	0.2	-0.3	0.7	-0.7	0.6	-0.7	-0.5	0.1	0.6	0.8
Qualifications: College or University degree	0.3	0.9	2.5	0.4	1.3	0.7	0.8	1.0	1.6	-0.8	0.9	-0.0	1.2	1.3	0.9	0.9
Eye problems/disorders: None of the above	0.3	0.3	2.1	0.2	0.2	-0.1	-0.3	-0.4	0.3	-1.4	0.1	-0.6	-0.6	-0.7	0.5	-0.0
Mean time to correctly identify matches	0.3	0.6	1.9	0.3	1.1	1.0	1.4	0.2	1.0	0.0	0.4	0.3	0.9	0.5	1.0	1.3
Whole body fat mass	0.3	1.1	4.5	0.8	1.0	0.8	0.4	0.4	-1.3	2.0	1.0	1.1	0.5	-2.1	-0.0	0.1
Leg fat mass (right)	0.3	1.1	4.3	1.0	1.0	0.7	0.2	0.6	-1.6	2.1	0.7	1.3	0.3	-1.8	-0.4	0.0
Arm predicted mass (right)	0.3	1.4	4.3	0.5	2.0	1.4	1.7	0.3	0.5	2.1	1.6	0.2	0.5	0.3	1.1	1.4
Overall health rating	0.3	0.7	1.8	0.0	0.7	1.1	1.2	0.3	0.5	0.5	1.2	0.9	0.3	-1.0	1.1	1.4
Leg pain on walking	0.3	0.4	2.0	0.9	0.1	0.3	-0.1	0.8	1.4	0.7	-0.1	0.6	0.8	0.2	-0.9	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.5	0.0	-0.7	-0.7	-1.1	-0.0	0.0	-0.6	-1.2	-0.1	-0.7	-0.1	-0.6	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.8	-1.0	-0.5	-0.7	-0.3	-0.6	0.8	-1.7	-0.5	-1.3	-0.5	0.5	0.9	0.1
Diabetes diagnosed by doctor	0.3	0.5	2.7	-0.1	0.6	-0.8	-0.7	0.1	-1.6	0.4	-0.7	-0.1	0.1	-0.5	-0.8	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.0	-0.7	-0.6	0.1	0.5	-0.5	-0.9	-0.9	-0.4	-0.1	-0.3	-0.2	1.0	0.7
Arm fat mass (left)	0.3	1.3	6.4	0.5	1.0	0.7	0.3	0.1	-1.9	2.0	0.9	0.9	0.3	-2.5	-0.0	0.0
Leg fat percentage (left)	0.3	1.0	4.3	0.9	0.7	0.7	0.1	0.6	-1.3	1.7	0.5	1.4	0.5	-2.1	-0.7	-0.0
Commuting to job workplace: Cycle	0.3	0.3	1.3	-1.1	0.0	-0.5	0.0	-1.1	0.3	-0.4	0.2	-1.1	-0.3	0.1	0.6	-0.3
Basal cell carcinoma (self-reported)	0.3	0.4	1.0	-0.2	-0.7	-0.7	-1.0	-0.2	0.3	-0.6	-1.0	-0.7	-0.4	0.1	-0.8	-0.7
Leg fat mass (left)	0.3	1.1	3.9	0.8	1.2	0.8	0.4	0.4	-1.6	1.9	0.8	1.1	0.3	-2.0	-0.1	0.2
Bipolar Disorder or Schizophrenia	0.2	0.6	2.9	0.4	1.2	0.5	0.6	0.3	1.7	0.0	-0.0	0.8	1.2	-0.6	-0.7	0.5
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.7	-0.8	1.0	0.6	0.9	-0.7	0.4	-0.6	1.0	-0.9	-0.1	-1.3	1.3	0.9
Schizophrenia vs Biploar Disorder	0.2	0.3	2.4	-0.6	-0.4	-0.2	-0.4	-0.2	-1.5	0.0	-0.0	-0.0	-0.1	-0.6	0.4	-0.4
Reaction Time	0.2	0.3	0.8	0.5	0.8	0.7	0.8	0.2	0.6	-0.0	-0.0	0.2	0.9	-0.0	0.7	0.8
Bipolar Disorder (2011)	0.2	0.1	0.7	0.5	0.4	0.5	0.2	0.2	0.8	-0.1	0.0	0.6	0.2	-0.1	-0.4	0.4
Fasting Glucose	0.2	0.3	0.9	-0.5	0.9	0.2	0.7	-0.7	0.5	-0.3	0.7	-0.5	-0.1	-0.2	0.3	0.6
HbA1C	0.2	0.2	1.5	-0.3	0.1	0.1	0.4	-0.5	0.5	-1.2	0.2	-0.1	0.4	0.4	0.1	0.1
Primary Biliary Cirrhosis	0.2	0.3	2.2	-0.6	-1.5	0.1	0.2	0.1	-0.4	0.1	-0.4	0.5	0.2	1.0	0.3	0.5
Rheumatoid Arthritis	0.2	0.3	1.1	-0.3	-0.7	0.3	0.6	-0.2	1.0	0.6	0.8	-0.2	-0.5	0.2	1.1	0.5
Schizophrenia (2014)	0.2	0.4	1.6	0.0	1.2	0.6	0.7	0.0	0.3	0.2	0.5	0.6	0.9	-1.0	-0.3	0.4
Blood Eosinophil Count	0.2	1.6	6.1	-1.3	-1.7	-1.5	-1.3	-1.1	1.1	-1.1	-1.1	-1.1	-0.8	-2.5	0.0	-1.4
Height	0.2	3.2	7.7	1.0	1.3	1.9	2.6	1.1	2.8	0.6	1.4	-0.2	1.2	2.7	2.2	2.7
Waist Hip Ratio (WHR)	0.2	0.8	4.5	-0.5	-0.1	-0.2	0.4	-1.0	-0.3	0.3	0.4	-0.8	-1.4	-2.1	1.5	0.4
Allergy or Eczema	0.2	0.6	3.1	0.4	-1.2	-0.4	-0.5	0.2	1.0	-1.1	-0.3	0.0	-0.4	1.8	-0.5	0.2
Respiratory disease	0.2	0.4	1.0	0.3	0.2	1.0	0.8	0.2	-0.6	0.6	0.7	0.8	0.9	-0.8	-0.2	0.6
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.6	-0.1	0.5	-0.8	-0.5	-0.2	-1.3	0.3	-0.9	-0.3	-0.4	0.1	-0.5	-1.0
Lung FVC	0.2	0.9	3.5	-1.9	-1.0	-0.8	-0.6	-1.1	-0.5	-1.9	-0.8	-1.2	-0.1	-0.6	-0.3	-0.5
Hand grip strength (left)	0.2	0.6	2.9	-1.7	-0.3	-0.7	-0.4	-1.2	-0.4	-1.0	-0.5	-1.0	-0.9	-0.3	0.4	-0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.4	-0.3	-0.0	-0.2	0.5	-0.3	-1.2	-0.5	-0.2	-0.5	-0.0	-0.0	0.9	0.3
Pack years adult smoking proportion	0.2	0.2	1.1	0.3	-0.5	-0.4	-0.3	0.3	-0.1	1.0	-0.3	0.2	-0.3	-1.1	-0.3	-0.3
Impedance of leg (right)	0.2	0.7	2.6	-0.5	-1.6	-0.6	-0.6	0.0	1.5	-1.6	-0.7	-0.1	-0.5	1.1	0.1	-0.2
Trunk fat percentage	0.2	1.0	4.5	0.7	0.9	0.8	0.5	0.4	-1.3	1.5	1.0	1.2	0.7	-2.1	-0.1	0.2
Hand grip strength (right)	0.2	0.6	1.8	-1.4	-0.4	-0.9	-0.5	-1.1	-0.1	-0.9	-0.4	-1.3	-1.0	-0.2	0.3	-0.5
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.8	-0.2	-0.9	-0.2	-0.1	-0.5	1.4	-1.3	0.2	-0.4	-0.6	1.2	0.2	0.6
Leg predicted mass (left)	0.2	0.8	3.9	0.9	1.4	0.9	0.9	0.4	-0.6	2.0	1.1	0.4	0.8	-0.3	0.4	0.6
Trunk fat mass	0.2	1.1	3.7	0.8	1.2	1.0	0.7	0.4	-1.0	1.9	1.2	1.1	0.8	-1.8	0.1	0.4
Financial difficulties in last 2 years	0.2	0.3	1.1	-0.6	0.4	0.3	0.9	-1.0	-0.5	-0.4	-0.0	-0.5	0.2	-0.6	0.1	0.6
Illnesses of siblings	0.2	0.3	1.3	-0.3	0.0	-0.1	-0.2	-0.5	-0.2	-0.6	0.4	-0.7	-1.0	-0.9	1.1	0.1
Weight	0.2	1.1	4.6	0.8	1.4	1.0	0.7	0.5	-1.0	2.1	1.1	0.9	0.8	-1.4	-0.0	0.4
Trunk fat-free mass	0.2	0.9	4.0	0.2	1.3	1.0	1.2	0.0	0.5	2.0	1.3	-0.2	0.5	0.2	1.0	1.0
Number of live births	0.2	0.3	1.2	-1.1	-0.2	-0.2	-0.3	-0.7	-1.0	-0.5	-0.3	-0.8	-0.3	-0.8	0.1	-0.4
Noisy workplace	0.2	0.2	0.7	0.4	-0.7	-0.3	-0.3	0.5	-0.8	0.7	-0.7	0.4	0.3	0.2	-0.5	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	1.2	0.1	-1.1	-0.0	0.0	0.3	1.0	-0.0	-0.3	0.0	0.4	0.8	-0.5	-0.1
Medication: Cholesterol lowering	0.2	0.4	2.1	0.6	0.3	0.3	0.5	1.1	0.2	0.9	-0.1	0.3	0.4	1.4	0.1	0.3
Depression (self-reported)	0.2	0.2	1.8	-0.6	-0.3	0.0	0.1	-0.3	0.4	-1.3	-0.2	0.0	0.2	0.6	0.5	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	4.0	-2.0	-0.1	-0.3	-0.1	-1.2	0.2	-1.5	0.2	-1.4	0.0	-0.2	0.5	0.2
Trunk predicted mass	0.2	1.0	4.2	0.2	1.4	1.1	1.3	0.1	0.5	2.1	1.3	-0.1	0.5	0.3	1.0	1.0
Peak expiratory flow (PEF)	0.2	0.4	1.8	-0.2	-0.3	-0.9	-0.5	-0.7	-0.1	-1.3	-0.5	-1.1	0.5	0.3	-0.6	-0.7
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.9	0.1	0.7	0.7	0.4	0.4	-0.5	0.9	0.6	0.2	0.5	-0.2	0.7	0.5
Forced vital capacity (FVC), Best measure	0.2	0.9	4.5	-2.1	-0.8	-0.6	-0.7	-1.2	-0.4	-1.6	-0.3	-1.5	-0.2	-0.1	0.3	-0.2
Number of full sisters	0.2	0.2	1.3	0.3	0.1	0.2	0.7	0.3	0.2	1.1	0.4	0.3	0.6	-0.6	-0.3	0.1
Had major operations	0.2	0.2	0.8	-0.4	0.7	0.0	0.3	-0.5	0.4	-0.1	-0.4	-0.5	-0.8	-0.9	0.3	-0.0
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.1	-0.3	-0.3	-0.7	-1.0	0.3	-0.1	-0.4	-0.2	-0.0	-0.3	0.8	-0.3	-0.3
Leg fat-free mass (right)	0.2	0.9	3.2	0.7	1.6	1.1	1.1	0.2	-0.5	1.8	1.2	0.2	0.9	-0.4	0.6	0.8
Average weekly red wine intake	0.2	0.4	1.1	-0.6	-0.5	-0.8	-1.0	0.2	0.1	-0.6	-1.0	0.4	-0.5	0.4	-0.7	-0.6
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.1	-0.4	-0.0	0.6	0.7	-0.0	0.3	0.8	1.0	-0.1	-0.3	0.5	0.4	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.7	-1.3	-0.3	0.1	0.2	-0.7	0.2	-1.3	0.7	-0.7	0.5	0.2	1.1	0.5
Whole body water mass	0.2	0.9	3.8	0.4	1.5	1.0	1.2	0.0	-0.1	1.9	1.3	-0.1	0.5	-0.1	0.9	0.9
Leg predicted mass (right)	0.2	0.8	2.9	0.6	1.6	1.0	1.1	0.1	-0.5	1.7	1.2	0.1	0.8	-0.4	0.7	0.8
Miserableness	0.2	0.3	1.5	-0.4	-0.4	-0.1	0.2	0.3	0.3	-1.0	-0.6	0.1	-0.2	1.2	-0.5	0.4
Medication: Atorvastatin	0.2	0.2	0.9	-0.0	0.8	0.0	0.2	0.2	1.0	0.9	-0.3	0.2	-0.2	0.0	-0.5	-0.2
Arm fat-free mass (left)	0.2	1.2	4.1	0.3	1.6	1.4	1.5	0.2	0.0	2.0	1.7	0.2	0.3	-0.3	1.1	1.3
Myopia	0.2	0.3	1.0	0.4	1.0	0.2	0.1	0.3	0.6	-0.1	0.4	0.1	0.8	0.8	-0.7	-0.2
Pack years of smoking	0.2	0.3	2.0	0.5	-0.5	-0.2	-0.1	0.6	-0.2	1.4	-0.1	0.4	0.2	-1.0	-0.4	-0.2
Arm predicted mass (left)	0.2	1.0	3.7	0.2	1.5	1.3	1.3	0.1	-0.0	1.9	1.4	0.2	0.3	-0.4	1.0	1.0
Blood White Count	0.1	0.9	9.1	0.5	0.1	-0.4	-0.3	0.2	-0.4	1.3	-0.2	0.1	-0.7	-3.0	-0.2	-0.9
Average weekly spirits intake	0.1	0.1	0.4	-0.6	-0.6	-0.1	0.1	0.1	0.6	0.2	0.1	0.4	0.3	0.2	0.3	0.2
Leg fat-free mass (left)	0.1	0.7	3.4	0.7	1.4	0.8	0.8	0.3	-0.7	1.9	1.0	0.3	0.7	-0.4	0.4	0.5
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.7	0.1	-0.8	0.3	-0.2	0.2	-0.4	-0.4	-0.0	0.1	0.0	-0.2	0.6	0.2
Impedance of leg (left)	0.1	0.7	3.0	-0.8	-1.1	-0.1	-0.0	-0.1	1.7	-1.7	-0.4	-0.2	-0.1	1.0	0.7	0.5
Allergy	0.1	0.2	1.3	0.6	0.8	0.1	0.2	0.5	-0.3	1.2	0.0	-0.1	0.1	-0.2	0.4	-0.2
Diabetes (self-reported)	0.1	0.2	0.7	-0.5	-0.1	-0.8	-0.4	-0.3	-0.8	-0.1	-0.6	-0.6	-0.2	0.2	-0.2	-0.8
Impedance of arm (right)	0.1	0.5	2.4	-0.6	-1.4	-0.8	-0.9	-0.3	0.3	-1.6	-0.7	-0.2	0.1	-0.4	0.1	-0.5
Impedance of arm (left)	0.1	0.3	2.1	-0.2	-1.0	-0.5	-0.6	-0.0	0.7	-1.4	-0.7	0.0	0.4	0.1	-0.0	-0.2
Birth weight of first child	0.1	0.3	1.7	-0.4	-1.3	-0.2	-0.3	-0.2	-0.5	-0.1	-0.1	-0.2	0.0	0.2	1.0	0.2
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	1.0	-0.2	-0.5	-0.1	-0.4	-0.0	-0.3	1.0	0.7	-0.2	-0.4	0.1	-0.2	-0.2
Chest pain or discomfort	0.1	0.2	1.0	-1.0	-0.9	-0.3	-0.1	-0.2	0.3	-0.4	-0.3	-0.6	0.1	0.4	0.1	-0.1
Whole body fat-free mass	0.1	0.8	3.7	0.4	1.4	1.0	1.2	0.1	0.1	1.9	1.2	-0.0	0.6	-0.0	0.9	0.9
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.7	0.0	0.6	-0.5	0.1	-0.1	0.8	-0.5	-0.1	-0.8	-0.5	-0.1	0.8	0.1
Breast cancer (self-reported)	0.1	0.1	0.8	0.1	0.3	-0.3	0.1	0.1	0.9	-0.2	-0.1	0.2	-0.4	0.0	0.4	-0.1
Osteoporosis (self-reported)	0.1	0.1	0.5	-0.1	-0.1	-0.2	0.2	-0.2	-0.4	-0.5	-0.2	-0.5	0.5	0.7	0.1	0.1
Osteoarthritis (self-reported)	0.1	0.2	0.9	0.2	0.9	0.2	0.1	0.1	0.6	0.0	0.3	0.1	0.8	0.4	0.1	0.1
Basal metabolic rate	0.1	0.8	3.8	0.5	1.4	1.0	1.0	0.1	-0.2	2.0	1.2	0.2	0.6	-0.5	0.6	0.7
Impedance of whole body	0.1	0.5	2.5	-0.2	-0.9	0.2	0.2	0.3	1.6	-1.3	0.1	0.2	0.5	1.0	0.5	0.7
Hair Pigment	0.0	1.1	4.8	0.3	-1.0	-1.1	-1.6	-0.0	-2.2	-0.3	-1.1	-0.2	-0.4	-0.1	-0.9	-1.7
Tanning	0.0	0.2	1.5	-0.2	1.2	0.6	0.4	-0.0	0.2	0.6	0.8	0.3	0.0	-0.1	0.2	-0.1
Qualifications: A levels/AS levels or equivalent	0.0	0.1	0.4	-0.6	0.1	0.0	0.2	-0.0	0.1	-0.1	0.0	-0.1	0.0	0.2	0.6	0.3
Pulse rate, automated reading	0.0	0.1	0.5	-0.2	0.4	-0.3	-0.5	0.1	-0.7	-0.2	-0.3	-0.4	-0.3	-0.0	0.2	-0.4

Hub : Genes

LINC00493

Models

Trait associations