Best TWAS P=1.69e-15 · Best GWAS P=3.67e-17 conditioned to 0.0879
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | ORC4 | 0.12 | 0.00 | lasso | 4 | 0.00 | 0.23200 | 7.9 | -7.9 | 2.1e-15 | -0.89 | 0.04 | 0.33 | TRUE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ORC4L | 0.07 | 0.04 | blup | 37 | 0.03 | 0.00061 | -5.7 | 7.1 | 9.5e-13 | 0.69 | 0.05 | 0.35 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ORC4L | 0.06 | 0.01 | blup | 37 | 0.03 | 0.00016 | 8.1 | 8.0 | 1.7e-15 | 0.84 | 0.01 | 0.97 | TRUE |