Best TWAS P=1.7e-09 · Best GWAS P=6.25e-09 conditioned to 0.421
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CPSF4 | 0.06 | 0.06 | blup | 313 | 0.07 | 6.6e-09 | -5.8 | -6.0 | 1.7e-09 | 0.91 | 0.01 | 0.99 | TRUE |
| 2 | METSIM | Adipose | ARPC1A | 0.02 | 0.02 | blup | 308 | 0.02 | 1.6e-03 | -4.8 | -5.3 | 9.2e-08 | 0.85 | 0.06 | 0.90 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZKSCAN5 | 0.03 | 0.04 | lasso | 2 | 0.03 | 1.0e-04 | -5.8 | -5.8 | 6.2e-09 | 1.00 | 0.00 | 0.99 | FALSE |