Best TWAS P=7.85e-14 · Best GWAS P=5.02e-14 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | CTTNBP2 | 0.12 | 0.08 | lasso | 7 | 0.09 | 6.0e-07 | -7.5 | -7.1 | 1.0e-12 | 0.92 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Nerve Tibial | NAA38 | 0.13 | 0.14 | lasso | 11 | 0.10 | 2.9e-07 | -5.1 | 5.2 | 2.6e-07 | -0.19 | 1.00 | 0.00 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | CTTNBP2 | 0.14 | 0.10 | lasso | 2 | 0.08 | 2.4e-07 | -7.5 | -7.5 | 7.9e-14 | 1.00 | 0.00 | 1.00 | TRUE |
| 4 | GTEx | Testis | CTTNBP2 | 0.19 | 0.10 | lasso | 2 | 0.07 | 7.0e-04 | -5.2 | -5.5 | 4.3e-08 | 0.56 | 0.13 | 0.15 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CTTNBP2 | 0.03 | 0.01 | blup | 90 | 0.01 | 1.0e-02 | -6.6 | -6.2 | 6.2e-10 | 0.66 | 0.06 | 0.74 | FALSE |