Best TWAS P=5.96e-20 · Best GWAS P=9.94e-24 conditioned to 0.00019
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | EPHX2 | 0.17 | 0.08 | lasso | 6 | 0.07 | 3.1e-06 | -4.3 | -6.4 | 1.2e-10 | 0.60 | 0.30 | 0.68 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | EPHX2 | 0.09 | 0.00 | blup | 124 | 0.02 | 1.6e-02 | -9.8 | -5.3 | 1.1e-07 | 0.48 | 0.03 | 0.67 | FALSE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | EPHX2 | 0.15 | 0.12 | lasso | 7 | 0.12 | 2.0e-04 | -9.8 | -8.2 | 3.1e-16 | 0.77 | 0.05 | 0.79 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CLU | 0.04 | 0.00 | blup | 66 | 0.01 | 1.1e-02 | -7.6 | 9.1 | 6.0e-20 | -0.63 | 0.01 | 0.60 | TRUE |