Best TWAS P=3.82e-08 · Best GWAS P=4.3e-08 conditioned to 0.242
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | MLLT10 | 0.06 | 0.02 | lasso | 4 | 0.03 | 0.0008 | 4.7 | -5.3 | 1.2e-07 | -0.88 | 0.09 | 0.90 | FALSE |
2 | GTEx | Skin Sun Exposed Lower leg | CASC10 | 0.08 | 0.02 | lasso | 5 | 0.01 | 0.0614 | 5.3 | 5.5 | 3.8e-08 | 0.91 | 0.04 | 0.91 | TRUE |