[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr15:73,604,139-76,589,495

Best TWAS P=2.39e-11 · Best GWAS P=2.63e-10 conditioned to 7.02e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex STOML1 0.14 0.13 lasso 6 0.13 5.4e-16 -5.7 -5.7 1.0e-08 0.16 0.18 0.82 FALSE
2 GTEx Adipose Subcutaneous STOML1 0.12 0.04 lasso 3 0.03 1.2e-03 -6.2 -5.8 5.8e-09 0.15 0.02 0.98 FALSE
3 GTEx Brain Cerebellum STOML1 0.20 0.19 enet 9 0.16 1.8e-05 -4.7 -5.7 1.5e-08 0.18 0.02 0.97 FALSE
4 GTEx Breast Mammary Tissue (Male) STOML1 0.21 -0.01 lasso 4 -0.01 5.4e-01 -6.0 -5.7 1.5e-08 0.20 0.03 0.32 FALSE
5 GTEx Colon Transverse CTD-2323K18.1 0.13 0.04 lasso 11 0.05 1.8e-03 -4.7 -5.2 2.6e-07 0.10 0.02 0.84 FALSE
6 GTEx Esophagus Mucosa STOML1 0.10 0.07 lasso 3 0.06 5.0e-05 -6.2 -5.9 3.4e-09 0.16 0.02 0.98 FALSE
7 GTEx Esophagus Muscularis STOML1 0.15 0.16 lasso 3 0.17 2.1e-10 -5.7 -5.5 3.9e-08 0.16 0.07 0.93 FALSE
8 GTEx Heart Left Ventricle STOML1 0.21 0.06 lasso 4 0.06 4.8e-04 -5.7 -5.4 8.3e-08 0.17 0.03 0.94 FALSE
9 GTEx Lung STOML1 0.14 0.10 lasso 4 0.12 1.5e-09 -5.7 -5.4 8.5e-08 0.17 0.04 0.96 FALSE
10 GTEx Nerve Tibial STOML1 0.18 0.15 enet 27 0.15 1.3e-10 -6.2 -5.9 2.8e-09 0.22 0.01 0.99 FALSE
11 GTEx Testis MAN2C1 0.25 0.26 lasso 4 0.28 1.1e-12 -4.7 -5.5 4.7e-08 0.08 0.02 0.96 FALSE
12 GTEx Whole Blood STOML1 0.14 0.07 lasso 5 0.06 5.8e-06 -5.6 -5.5 4.7e-08 0.19 0.06 0.94 FALSE
13 YFS Blood PML 0.05 0.05 lasso 6 0.05 3.8e-16 -6.0 -5.7 9.9e-09 0.21 0.03 0.97 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma STOML1 0.03 0.02 blup 62 0.02 1.9e-04 -5.2 -6.2 6.6e-10 0.26 0.03 0.97 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SNUPN 0.11 0.06 blup 38 0.06 3.9e-04 -4.6 -5.7 1.0e-08 0.11 0.00 0.82 TRUE
16 The Cancer Genome Atlas Brain Lower Grade Glioma STOML1 0.03 0.03 lasso 4 0.03 3.4e-04 -6.0 -6.0 1.7e-09 0.20 0.02 0.98 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma STOML1 0.02 0.01 blup 62 0.00 2.4e-01 -5.7 -6.7 2.4e-11 0.28 0.02 0.73 TRUE
18 The Cancer Genome Atlas Pancreatic Adenocarcinoma MAN2C1 0.08 0.02 blup 14 0.04 1.3e-02 -4.1 -5.2 2.4e-07 0.10 0.00 0.04 FALSE
19 The Cancer Genome Atlas Pancreatic Adenocarcinoma STOML1 0.12 0.08 lasso 6 0.08 2.4e-04 -5.7 -5.2 2.2e-07 0.10 0.02 0.64 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma MAN2C1 0.07 0.04 blup 15 0.05 6.6e-06 3.5 -5.3 1.3e-07 0.05 0.00 0.12 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma STOML1 0.07 0.05 lasso 7 0.04 1.9e-05 -6.0 -6.0 2.4e-09 0.18 0.02 0.98 FALSE
22 The Cancer Genome Atlas Thyroid Carcinoma MAN2C1 0.09 0.05 blup 13 0.06 3.1e-06 3.5 -5.7 1.0e-08 0.06 0.00 0.15 FALSE
23 The Cancer Genome Atlas Thyroid Carcinoma STOML1 0.09 0.09 blup 62 0.10 3.7e-10 -5.2 -6.5 1.0e-10 0.32 0.03 0.97 FALSE