Best TWAS P=2.64e-08 · Best GWAS P=2.19e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Nucleus accumbens basal ganglia | UBE2G1 | 0.18 | 0.05 | lasso | 3 | 0.02 | 0.074 | 5.4 | -5.3 | 1.1e-07 | -0.95 | 0.04 | 0.82 | FALSE |
2 | GTEx | Breast Mammary Tissue (Female) | ZZEF1 | 0.11 | -0.01 | lasso | 2 | 0.00 | 0.462 | 5.6 | 5.6 | 2.6e-08 | 0.99 | 0.04 | 0.51 | TRUE |