Best TWAS P=3.19e-09 · Best GWAS P=1.46e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | UBE2Z | 0.18 | 0.00 | lasso | 5 | 0.01 | 3.0e-02 | 2.4 | -5.6 | 2.6e-08 | 0.37 | 0.07 | 0.12 | FALSE |
2 | GTEx | Cells Transformed fibroblasts | ZNF652 | 0.14 | 0.14 | lasso | 3 | 0.15 | 1.2e-11 | -6.0 | -5.9 | 4.2e-09 | 0.93 | 0.00 | 1.00 | FALSE |
3 | YFS | Blood | ZNF652 | 0.02 | 0.02 | lasso | 4 | 0.02 | 1.3e-07 | -6.0 | -5.9 | 3.2e-09 | 0.97 | 0.00 | 1.00 | TRUE |