Best TWAS P=3.22e-14 · Best GWAS P=2.29e-11 conditioned to 0.399
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | DNAH17 | 0.04 | 0.01 | blup | 99 | 0.02 | 1.2e-05 | 1.7 | 5.3 | 1.1e-07 | -0.35 | 0.64 | 0.04 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PGS1 | 0.04 | 0.03 | blup | 67 | 0.04 | 1.8e-08 | 4.4 | 6.3 | 2.9e-10 | -0.51 | 0.79 | 0.19 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PGS1 | 0.08 | 0.06 | enet | 15 | 0.08 | 8.8e-10 | -6.3 | 7.0 | 3.0e-12 | -0.80 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | DNAH17 | 0.14 | 0.04 | blup | 99 | 0.04 | 1.2e-02 | -6.6 | 6.5 | 5.7e-11 | -0.66 | 0.01 | 0.71 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PGS1 | 0.08 | 0.01 | blup | 68 | 0.04 | 5.6e-05 | -6.5 | 7.6 | 3.2e-14 | -0.82 | 0.02 | 0.97 | TRUE |