Best TWAS P=6.78e-08 · Best GWAS P=2.7e-07 conditioned to 0.116
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | DMWD | 0.11 | 0.13 | lasso | 2 | 0.16 | 7.3e-09 | -4.4 | -5.1 | 2.9e-07 | -0.75 | 0.04 | 0.94 | TRUE |
2 | GTEx | Skin Sun Exposed Lower leg | SNRPD2 | 0.25 | 0.17 | lasso | 5 | 0.17 | 6.5e-14 | 5.0 | -5.4 | 6.8e-08 | -0.26 | 0.01 | 0.99 | TRUE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | SNRPD2 | 0.04 | 0.03 | enet | 7 | 0.03 | 2.6e-04 | 4.9 | -5.3 | 1.1e-07 | -0.25 | 0.00 | 0.98 | FALSE |