TWAS hub - OPRL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1760	0.0640	5.2e-03	-0.003	NA	0.006	NA	0.007	8.7e-01	NA	9.8e-02	NA	8.4e-02
2	GTEx	Adipose Visceral Omentum	0.2830	0.1310	8.1e-03	0.030	NA	0.006	NA	0.041	1.1e-02	NA	1.4e-01	NA	3.3e-03
3	GTEx	Adrenal Gland	0.4772	0.0843	7.5e-07	0.286	NA	0.224	NA	0.178	7.8e-11	NA	1.5e-08	NA	5.5e-07
4	GTEx	Artery Aorta	0.2670	0.0620	5.9e-07	0.187	NA	0.159	NA	0.168	1.5e-10	NA	4.5e-09	NA	1.4e-09
5	GTEx	Artery Coronary	0.3660	0.1180	4.2e-03	0.180	NA	0.057	NA	0.133	1.1e-06	NA	5.6e-03	NA	3.1e-05
6	GTEx	Artery Tibial	0.0968	0.0417	7.0e-03	0.095	NA	0.042	NA	0.063	6.7e-08	NA	2.8e-04	NA	1.1e-05
7	GTEx	Brain Cerebellar Hemisphere	0.2700	0.0990	3.5e-03	0.141	NA	0.130	NA	0.168	1.8e-04	NA	3.4e-04	NA	4.5e-05
8	GTEx	Cells Transformed fibroblasts	0.2550	0.0510	1.1e-08	0.067	NA	0.116	NA	0.111	9.8e-06	NA	5.5e-09	NA	1.1e-08
9	GTEx	Esophagus Muscularis	0.1650	0.0540	1.7e-03	0.141	NA	0.097	NA	0.126	7.2e-09	NA	1.8e-06	NA	4.7e-08
10	GTEx	Heart Atrial Appendage	0.3650	0.1210	1.7e-03	0.045	NA	0.059	NA	0.081	4.4e-03	NA	1.2e-03	NA	1.7e-04
11	GTEx	Heart Left Ventricle	0.2052	0.0913	5.8e-03	0.003	NA	-0.004	NA	0.010	2.2e-01	NA	5.7e-01	NA	9.3e-02
12	GTEx	Nerve Tibial	0.2039	0.0504	3.2e-06	0.154	NA	0.137	NA	0.141	4.5e-11	NA	6.1e-10	NA	3.3e-10
13	GTEx	Pancreas	0.3890	0.0760	1.0e-06	0.272	NA	0.288	NA	0.315	6.7e-12	NA	1.3e-12	NA	6.9e-14
14	GTEx	Skin Sun Exposed Lower leg	0.1400	0.0380	1.7e-05	0.103	NA	0.095	NA	0.106	7.8e-09	NA	2.9e-08	NA	4.3e-09
15	GTEx	Stomach	0.3560	0.0710	1.2e-06	0.230	NA	0.193	NA	0.188	2.4e-11	NA	1.3e-09	NA	2.4e-09
16	GTEx	Thyroid	0.3400	0.0820	5.5e-06	0.053	NA	0.068	NA	0.092	6.7e-05	NA	7.0e-06	NA	1.7e-07
17	GTEx	Whole Blood	0.0860	0.0350	4.6e-03	0.059	NA	0.071	NA	0.052	4.2e-06	NA	4.3e-07	NA	1.5e-05
18	NTR	Blood	0.0665	0.0181	3.7e-07	0.019	0.029	0.026	0.029	0.024	6.4e-07	9.2e-10	6.2e-09	8.5e-10	1.8e-08
19	ROSMAP	Brain Pre-frontal Cortex	0.1448	0.0396	1.0e-06	0.092	0.059	0.076	0.060	0.082	6.3e-12	4.0e-08	4.9e-10	3.2e-08	1.2e-10
20	YFS	Blood	0.0714	0.0145	0.0e+00	0.070	0.073	0.086	0.080	0.087	6.7e-22	7.7e-23	1.2e-26	7.1e-25	5.0e-27
21	TCGA	Brain Lower Grade Glioma	0.0250	0.0137	7.1e-03	0.020	0.006	0.000	NA	0.008	2.3e-03	6.3e-02	3.2e-01	NA	3.5e-02
22	TCGA	Prostate Adenocarcinoma	0.0746	0.0275	3.8e-07	0.084	0.074	0.074	NA	0.081	4.3e-09	3.8e-08	3.3e-08	NA	7.8e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
High cholesterol (Self-reported)	14.8	26.2	48.8	-0.9	-1.1	-5.7	-6.2	0.3	-6.2	-6.0	-6.2	-6.0	0.3	-0.9	-6.1	-6.7	-6.9	-5.8	-2.3	7.0	3.2	-2.8	6.5	-6.0	-6.4
Cardiovascular Disease	13.8	45.5	84.0	-1.0	-2.2	-7.8	-9.2	0.7	-8.6	-7.6	-7.2	-8.3	-0.9	-1.1	-8.7	-8.8	-8.7	-8.2	-3.4	8.5	4.1	-2.7	8.0	-8.3	-7.5
Medication for cholesterol, blood pressure or diabetes	13.8	22.8	38.4	0.7	1.4	5.2	6.0	-0.9	5.8	5.7	5.7	5.7	0.0	1.0	5.7	6.2	6.1	5.8	2.4	-6.2	-2.9	2.5	-6.0	5.7	6.1
Medication: Cholesterol lowering	13.4	20.9	37.2	-0.5	-0.9	-4.7	-5.5	1.1	-5.6	-5.7	-5.2	-5.5	0.9	-0.7	-5.3	-6.1	-5.8	-4.8	-1.9	6.0	3.0	-3.7	5.8	-5.5	-5.7
Medication: Simvastatin	13.0	19.0	33.2	-0.6	-1.4	-4.7	-5.5	1.3	-5.7	-5.5	-4.3	-5.6	0.5	-0.7	-5.4	-5.8	-5.5	-4.7	-1.5	5.5	2.7	-3.3	5.3	-5.6	-5.1
Cholesterol lowering medication	12.5	18.4	33.3	-0.8	-0.3	-4.7	-5.2	0.1	-5.4	-5.1	-5.0	-5.2	0.1	-0.3	-5.1	-5.5	-5.7	-5.0	-1.2	5.8	3.0	-2.8	5.5	-5.2	-4.9
Medication: Aspirin	10.8	14.3	26.0	0.5	-0.9	-4.2	-4.3	-0.2	-4.4	-5.1	-3.8	-4.5	0.2	-1.6	-4.3	-4.7	-4.5	-4.0	-1.5	4.7	3.0	-4.2	4.9	-4.5	-4.9
Vascular/heart problems diagnosed by doctor	10.8	29.6	56.5	0.6	1.8	6.3	7.5	-0.0	6.8	6.3	6.0	6.7	1.5	1.7	7.0	6.7	6.7	7.3	2.6	-6.4	-3.4	2.5	-6.3	6.7	5.9
Medication: Aspirin	10.6	13.8	24.8	0.1	-0.9	-4.2	-4.2	-0.2	-4.4	-5.0	-3.8	-4.5	-0.1	-1.8	-4.3	-4.5	-4.4	-4.1	-1.6	4.5	3.0	-4.1	4.6	-4.5	-4.7
Angina	9.9	13.0	23.6	-0.8	0.5	-3.7	-4.6	-0.1	-4.4	-4.6	-4.0	-4.5	0.6	-0.7	-4.3	-4.5	-4.2	-4.6	-0.9	4.2	3.0	-2.2	4.5	-4.5	-4.9
Angina (self-reported)	9.7	12.7	23.4	-1.0	0.1	-3.8	-4.6	-0.1	-4.3	-4.5	-4.0	-4.4	0.3	-1.1	-4.3	-4.4	-4.1	-4.6	-1.1	4.2	3.1	-2.1	4.4	-4.4	-4.8
Ulcerative Colitis (UC)	8.5	16.0	26.5	2.2	1.2	3.9	4.9	0.4	5.1	4.5	4.4	5.1	0.2	1.1	5.0	5.1	5.0	4.2	1.6	-5.1	-3.8	2.5	-5.0	5.1	4.2
Number of self-reported non-cancer illnesses	8.5	14.7	24.2	-0.3	-1.7	-4.5	-4.2	-0.6	-4.6	-4.4	-4.0	-4.5	-0.2	-2.2	-4.5	-4.8	-4.9	-3.7	-2.3	4.8	4.8	-2.4	4.5	-4.5	-4.4
High blood pressure	8.0	22.2	46.5	-0.5	-1.4	-5.5	-6.8	0.4	-6.0	-5.2	-5.1	-5.9	-1.4	-1.4	-6.3	-5.7	-5.8	-6.6	-2.4	5.6	2.6	-1.5	5.2	-5.9	-4.9
Waist Hip Ratio (WHR)	7.9	35.6	63.9	-1.7	-1.5	-7.8	-7.0	-2.3	-7.3	-6.7	-6.7	-7.0	-2.5	-1.7	-6.8	-7.4	-8.0	-7.1	-2.5	7.9	5.2	-3.2	7.3	-7.0	-6.0
Systolic blood pressure, automated reading	7.9	22.9	46.4	-0.7	-1.0	-5.5	-6.8	-0.3	-6.4	-5.4	-4.7	-6.3	-1.1	-0.6	-6.5	-6.0	-6.0	-6.6	-1.2	5.5	2.3	-1.2	5.6	-6.3	-4.9
Systolic Blood Pressure	7.4	37.1	76.0	-1.0	-1.4	-6.8	-8.7	1.1	-8.0	-6.8	-6.4	-7.7	-1.1	0.6	-8.0	-8.1	-8.0	-7.8	-1.5	7.7	1.5	-2.2	7.4	-7.7	-6.4
Illnesses of father: Heart disease	7.4	10.3	18.3	-1.3	0.5	-3.5	-3.8	-0.3	-3.9	-3.6	-4.3	-3.8	0.3	0.1	-3.8	-4.1	-4.2	-4.2	-0.3	4.2	2.0	-1.6	4.2	-3.8	-3.9
Hypertension (Self-reported)	7.3	20.3	42.3	-0.2	-0.9	-5.3	-6.5	0.1	-5.7	-4.9	-4.9	-5.6	-1.3	-1.3	-6.0	-5.5	-5.7	-6.3	-2.1	5.4	2.8	-1.1	5.0	-5.6	-4.6
Medication: Ramipril	7.0	9.0	17.4	0.3	-1.7	-3.7	-3.9	-0.1	-3.9	-3.5	-3.3	-3.8	-2.2	-0.6	-3.6	-3.4	-3.5	-4.2	-1.2	3.3	2.3	-2.5	3.2	-3.8	-2.4
Rheumatoid Arthritis	6.8	9.3	15.6	3.2	0.8	3.1	3.3	0.0	3.8	3.6	3.4	3.7	-0.9	0.0	3.6	3.9	4.0	3.2	2.0	-3.9	-1.4	2.0	-3.8	3.7	3.5
Medication for cholesterol	6.7	10.1	17.2	-0.3	1.7	4.1	4.1	0.9	4.1	3.8	2.9	4.1	1.9	1.4	4.0	3.6	3.9	4.0	1.3	-3.6	-2.6	2.4	-3.4	4.1	2.9
Body Mass Index (BMI) (2010)	6.0	8.2	12.6	1.9	2.2	3.2	3.5	0.3	3.4	3.5	3.4	3.4	0.8	0.0	3.2	3.5	3.3	2.8	2.6	-3.4	-1.4	3.1	-3.2	3.2	3.0
Ovarian Cancer	5.9	7.8	18.4	-0.0	1.2	2.7	3.1	-1.4	3.4	3.4	2.5	3.3	-0.6	0.2	3.0	3.6	3.4	1.4	1.4	-3.5	-3.6	4.3	-3.4	3.3	2.7
Had other major operations	5.9	7.2	14.8	2.4	0.3	3.4	3.4	0.7	3.4	2.7	3.0	3.1	1.2	-0.4	3.3	3.4	3.8	3.6	0.6	-3.4	-0.6	0.5	-3.2	3.1	2.5
Birth weight of first child	5.9	10.8	20.5	0.6	-0.4	2.8	4.5	-1.4	4.2	4.0	3.9	4.1	-1.0	-0.5	4.4	4.0	4.0	3.7	-0.3	-4.2	-1.0	2.2	-4.3	4.1	4.0
Diabetes diagnosed by doctor	5.8	9.5	15.8	1.1	-2.7	-3.2	-3.1	1.4	-3.5	-3.8	-3.3	-3.4	-0.3	-2.5	-2.9	-3.4	-3.1	-2.6	-3.7	3.6	4.0	-3.6	3.3	-3.4	-2.9
Medication: Atorvastatin	5.6	6.9	14.0	-0.5	0.8	-2.8	-3.2	-0.9	-3.0	-2.9	-3.6	-2.8	0.4	0.1	-2.8	-3.4	-3.7	-3.4	-0.6	3.7	1.0	-1.3	3.6	-2.8	-3.5
Medication: Blood pressure	5.4	9.5	17.8	-0.3	-0.9	-3.4	-4.1	0.8	-3.6	-3.3	-4.1	-3.5	-0.5	-0.5	-3.6	-4.0	-4.0	-4.2	-1.7	3.9	1.8	-0.7	3.8	-3.5	-3.9
Medication: Blood pressure	5.2	9.9	20.1	-0.1	-1.4	-4.0	-4.5	-0.6	-4.0	-3.4	-3.0	-3.9	-1.5	-1.4	-4.2	-3.7	-4.1	-4.2	-1.7	3.6	2.6	-0.9	3.3	-3.9	-3.0
Heart attack	5.0	6.4	12.8	0.1	-0.4	-2.3	-3.4	0.3	-2.9	-3.6	-3.1	-3.1	-0.3	-0.3	-3.0	-3.0	-2.5	-3.0	-0.8	2.7	1.7	-3.3	2.9	-3.1	-3.4
LDL Cholesterol	4.9	7.7	14.0	-1.6	-0.4	-2.8	-3.7	0.1	-3.6	-3.3	-2.9	-3.5	-0.4	0.0	-3.5	-3.7	-3.5	-3.5	-0.6	3.5	0.5	-2.0	3.2	-3.7	-2.9
Heart attack/myocardial infarction (self-reported)	4.9	6.4	12.9	0.2	-0.4	-2.2	-3.4	0.5	-2.9	-3.6	-2.9	-3.1	-0.1	-0.2	-3.0	-3.0	-2.4	-2.9	-0.8	2.7	1.8	-3.4	2.9	-3.1	-3.3
Heart disease (mother)	4.6	5.6	11.2	-0.1	-1.9	-3.3	-3.0	-1.1	-2.8	-2.4	-2.4	-2.7	-2.0	-1.8	-2.8	-2.4	-2.8	-3.1	-1.8	2.7	1.8	-1.1	2.5	-2.7	-2.1
Type 2 Diabetes (T2D) (2018)	4.5	8.4	21.5	0.5	-2.2	-3.1	-2.7	1.4	-3.1	-3.4	-3.6	-3.0	-0.5	-2.0	-2.5	-3.3	-3.1	-2.6	-2.9	3.5	4.6	-2.8	3.4	-3.0	-2.9
Diabetes (mother)	4.5	5.7	12.5	0.0	0.7	-2.4	-2.5	-0.8	-3.1	-2.7	-2.0	-3.0	1.0	0.4	-2.8	-3.2	-3.5	-2.8	0.5	3.3	2.5	-0.3	2.9	-3.0	-3.0
Lung FVC	4.3	21.9	36.6	-0.8	4.9	6.0	5.3	0.5	5.0	5.4	4.9	4.8	2.4	4.5	4.6	5.5	5.5	3.9	5.0	-6.0	-3.6	3.2	-5.8	4.8	5.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.3	9.1	16.9	0.1	2.3	3.4	3.3	-1.5	3.4	4.1	3.1	3.5	0.2	2.1	3.0	3.4	3.1	2.4	3.1	-3.6	-2.5	3.6	-3.5	3.5	3.5
Medication: Lisinopril	4.3	5.5	10.7	0.3	1.0	-2.3	-3.0	-0.0	-3.2	-2.7	-2.3	-3.1	0.7	0.9	-3.1	-3.3	-3.1	-2.5	0.2	2.9	1.6	-1.4	2.6	-3.1	-2.4
Breast Cancer	4.2	10.0	18.8	-1.7	-0.1	-4.1	-3.9	-2.3	-4.2	-3.4	-2.7	-4.1	-0.8	-1.4	-4.3	-4.0	-4.2	-4.0	-0.9	3.9	1.2	-1.1	3.5	-4.1	-2.8
Irritable Bowel Disease (IBD)	4.1	9.8	18.9	1.8	0.2	2.4	4.3	0.3	4.2	3.5	2.8	4.2	-0.7	-0.5	4.3	4.1	3.9	3.1	-0.1	-4.1	-2.3	1.9	-4.0	4.2	3.1
Diabetes (self-reported)	3.9	6.0	10.6	0.5	-2.1	-2.4	-2.2	1.6	-2.7	-3.1	-3.0	-2.7	-0.0	-1.9	-2.1	-2.6	-2.2	-2.1	-2.9	2.9	3.0	-3.3	2.8	-2.7	-2.3
Back pain experienced in last month	3.9	5.7	13.3	1.7	1.2	3.3	2.5	1.6	2.7	2.3	3.0	2.4	0.9	1.3	2.3	3.2	3.6	2.7	1.4	-3.3	-1.2	0.8	-3.2	2.4	2.5
Breast cancer (self-reported)	3.9	4.6	12.3	2.5	0.1	3.5	2.5	2.6	2.4	1.4	2.0	2.1	2.2	1.8	2.5	2.4	3.1	2.7	1.4	-2.3	-1.0	-0.3	-1.5	2.1	1.2
Illnesses of father: None of the above (group 1)	3.8	4.8	8.9	-1.1	-1.2	2.6	2.4	0.5	2.6	2.2	2.7	2.5	0.1	-0.9	2.3	2.8	3.0	2.6	-1.0	-3.0	-1.8	0.5	-2.9	2.5	2.4
Illnesses of siblings	3.6	5.1	11.3	0.8	0.9	2.1	2.9	-0.2	2.6	2.5	2.8	2.5	0.4	1.2	2.6	2.6	2.7	3.4	1.2	-2.7	-2.2	1.1	-2.7	2.5	2.6
Medication: Gliclazide	3.6	4.1	7.8	0.1	-1.9	-2.3	-2.1	-0.2	-2.2	-2.2	-2.0	-1.9	-0.3	-2.0	-1.9	-2.6	-2.7	-1.6	-2.8	2.5	1.4	-2.5	2.4	-1.9	-1.7
Pain experienced in last month	3.6	6.0	14.6	-2.7	-1.3	-3.1	-2.2	-1.5	-2.8	-2.2	-3.1	-2.5	-0.7	-1.8	-2.1	-3.4	-3.8	-2.3	-1.9	3.6	-0.1	-1.1	3.2	-2.5	-2.2
Loud music exposure frequency	3.3	3.6	6.0	1.9	0.1	2.0	1.7	-0.0	2.3	2.4	2.1	2.3	-0.1	0.4	2.2	2.4	2.4	2.4	0.4	-2.4	-0.9	1.7	-2.3	2.3	2.2
Medication: Paracetamol	3.3	5.1	10.9	1.0	0.4	2.4	2.3	-0.5	2.7	2.5	2.9	2.5	-0.6	-0.3	2.4	3.1	3.1	1.7	0.7	-3.3	-2.6	1.3	-3.0	2.5	2.6
High blood pressure (siblings)	3.1	4.4	8.2	-0.9	-0.9	-2.2	-2.5	-0.9	-2.3	-2.1	-2.8	-2.2	-0.7	-1.8	-2.4	-2.5	-2.9	-2.9	-1.4	2.5	1.8	-0.9	2.5	-2.2	-2.3
Number of live births	3.0	4.2	8.3	1.3	0.6	-2.4	-2.8	-0.3	-2.8	-2.5	-1.0	-2.7	0.5	0.4	-2.9	-2.7	-2.7	-2.1	0.3	2.6	1.8	-1.0	2.3	-2.7	-2.0
Ever had stillbirth, spontaneous miscarriage or termination	2.9	3.1	7.2	1.1	0.7	-1.4	-1.8	1.2	-2.1	-2.1	-2.1	-2.0	0.6	1.7	-1.8	-2.4	-2.1	-1.4	0.9	2.7	0.6	-1.6	2.6	-2.0	-1.7
Impedance of whole body	2.8	14.4	29.9	-2.0	-0.8	-4.1	-3.0	0.7	-4.3	-4.7	-4.9	-4.0	0.2	-0.1	-3.7	-5.2	-5.2	-3.2	-0.4	5.4	3.4	-4.3	5.5	-4.0	-4.9
Happiness	2.7	3.3	6.9	0.9	1.2	2.2	1.4	2.0	1.7	1.8	2.6	1.6	0.8	1.8	1.3	2.1	2.4	1.9	1.2	-2.6	-1.0	0.8	-2.5	1.6	2.4
Tinnitus: Yes, now most or all of the time	2.7	3.2	5.5	-0.4	1.1	-1.3	-1.9	0.6	-2.1	-2.2	-1.9	-2.2	1.0	0.7	-2.2	-2.1	-1.9	-1.5	1.1	2.1	1.8	-1.7	2.3	-2.2	-2.3
Hypothyroidism (self reported)	2.6	6.0	14.0	1.7	0.7	-3.3	-2.2	-2.5	-2.7	-2.3	-2.7	-2.4	-1.2	-0.4	-2.1	-3.2	-3.7	-3.4	0.2	3.4	3.0	-0.9	2.8	-2.4	-2.0
Illness, injury, bereavement, stress in last 2 years	2.6	3.2	8.3	-0.9	0.4	1.4	1.2	-0.7	1.6	2.2	2.3	1.5	-1.1	0.4	0.9	2.3	1.9	0.3	1.2	-2.6	-2.9	2.7	-2.6	1.5	2.2
Medication: Metformin	2.5	3.5	8.9	1.4	-2.0	-2.0	-2.0	0.6	-2.0	-2.1	-1.5	-2.0	-0.0	-2.4	-1.7	-1.7	-1.7	-1.2	-3.0	1.8	2.3	-2.5	1.6	-2.0	-1.1
Forced expiratory volume in 1-second (FEV1)	2.5	8.4	15.5	-1.2	1.8	3.6	3.3	0.2	3.3	3.4	2.5	3.2	0.5	2.5	3.1	3.3	3.6	2.6	2.8	-3.6	-3.9	2.1	-3.1	3.2	3.2
Illnesses of mother	2.5	3.1	6.8	0.6	0.3	2.4	2.2	0.7	2.5	1.8	1.7	2.4	0.7	1.0	2.4	2.0	2.3	2.6	1.2	-2.0	-0.9	0.2	-1.6	2.4	1.2
Impedance of arm (left)	2.5	11.5	25.6	-1.2	-0.7	-3.5	-2.0	0.0	-3.6	-4.2	-4.6	-3.3	0.3	-0.4	-2.5	-4.7	-4.7	-2.2	-0.5	5.0	3.5	-4.9	5.1	-3.3	-4.3
Medication: Paracetamol	2.5	4.1	8.8	1.3	0.9	2.5	2.0	-0.1	2.3	2.2	2.7	2.1	-0.0	0.4	2.0	2.8	2.8	1.5	1.2	-3.0	-2.0	1.3	-2.6	2.1	2.4
Qualifications: NVQ or HND or HNC or equivalent	2.5	3.0	5.2	0.2	0.3	-2.3	-1.7	-1.6	-1.8	-2.1	-2.2	-1.8	-1.2	-0.4	-1.9	-2.0	-1.9	-2.3	-0.1	1.8	1.8	-1.7	2.2	-1.8	-2.0
Mouth/teeth dental problems: Mouth ulcers	2.5	3.9	7.2	1.1	-0.2	2.5	2.5	-0.5	2.7	2.2	2.1	2.6	0.5	-0.8	2.3	2.6	2.7	2.4	0.4	-2.3	-1.3	1.3	-2.1	2.6	1.8
HDL Cholesterol	2.3	3.9	6.8	0.7	-0.1	1.6	2.5	-2.0	2.6	2.3	2.1	2.5	-0.8	0.0	2.4	2.6	2.4	2.2	0.3	-2.3	-1.9	1.1	-2.1	2.6	2.0
Triglycerides	2.3	3.7	7.4	-0.3	-0.2	-1.8	-2.7	0.7	-2.5	-2.5	-1.7	-2.5	0.0	0.0	-2.5	-2.4	-2.2	-2.7	-0.7	2.2	0.9	-2.0	2.1	-2.6	-2.0
Medication: Atenolol	2.3	2.9	5.9	-0.5	-1.1	-1.7	-2.4	0.8	-1.9	-1.8	-2.0	-1.9	-0.7	-0.1	-2.0	-2.0	-2.0	-2.0	-1.6	2.2	-0.6	-0.0	2.0	-1.9	-2.4
Impedance of arm (right)	2.3	10.6	22.0	-1.6	-1.0	-3.5	-2.2	-0.1	-3.5	-4.0	-4.6	-3.3	-0.0	-0.9	-2.7	-4.4	-4.4	-2.6	-1.1	4.6	3.0	-4.2	4.7	-3.3	-4.1
Medication: Bendroflumethiazide	2.3	3.5	8.0	-0.7	-0.3	-2.2	-2.8	-0.7	-2.5	-2.1	-1.6	-2.5	-0.2	-1.1	-2.6	-2.1	-2.2	-2.7	-1.6	2.0	1.0	-0.1	1.7	-2.5	-1.8
Bipolar Disorder (2018)	2.2	3.4	7.5	0.8	0.4	2.1	2.6	1.1	2.4	1.9	1.6	2.3	1.2	-0.6	2.7	2.3	2.5	2.7	-0.4	-2.0	0.6	0.8	-1.8	2.3	1.7
Type 2 Diabetes (T2D) (2012)	2.2	2.6	7.4	-0.2	-1.1	-2.3	-2.1	0.5	0.0	-2.2	-2.3	0.0	-0.6	-1.0	-1.9	0.0	-2.2	-1.6	-1.4	2.3	2.7	-1.8	2.1	0.0	0.0
Gout (self-reported)	2.2	3.0	5.9	1.1	0.3	-2.0	-1.9	-0.7	-2.1	-1.8	-2.4	-1.9	-0.5	-0.1	-1.8	-2.2	-2.4	-2.1	-0.6	2.4	1.7	-1.0	2.0	-1.9	-1.8
Supplements: Vitamin C	2.2	2.6	5.2	-0.9	0.2	-1.8	-1.8	-0.3	-1.8	-2.1	-1.9	-1.8	-0.6	0.4	-2.1	-2.0	-1.9	-1.8	0.5	1.7	0.7	-2.3	2.0	-1.8	-1.9
Basal cell carcinoma (self-reported)	2.2	2.6	6.3	0.8	0.1	-1.4	-1.0	-0.4	-1.7	-2.1	-1.6	-1.7	0.6	0.3	-1.3	-2.2	-2.0	-1.0	0.3	2.4	2.5	-2.1	2.4	-1.7	-1.9
Impedance of leg (left)	2.1	10.2	19.3	-2.4	-0.5	-3.6	-3.1	0.9	-3.8	-3.8	-3.6	-3.6	0.3	-0.0	-3.7	-4.3	-4.4	-3.3	-0.3	4.3	2.6	-2.5	4.2	-3.6	-4.1
Age at First Birth	2.0	3.0	7.2	-2.7	-1.0	-1.1	-1.6	0.9	-2.0	-1.8	-2.2	-1.9	0.6	0.0	-1.8	-2.2	-2.0	-1.0	-1.3	2.4	1.4	-1.0	2.3	-1.9	-1.9
Ulcerative Colitis	2.0	2.9	6.2	2.5	1.0	1.7	2.3	0.7	0.0	2.0	2.1	0.0	0.3	1.2	2.4	2.1	2.1	1.8	1.1	-2.3	-1.8	1.3	-2.4	0.0	2.1
Forced vital capacity (FVC)	2.0	7.6	13.6	-1.1	1.8	3.7	3.3	0.7	3.1	3.1	2.3	3.0	0.9	2.5	3.1	3.1	3.5	2.5	2.7	-3.4	-3.6	1.0	-2.8	3.0	3.0
Peak expiratory flow (PEF)	2.0	4.7	9.9	0.4	0.3	2.6	2.5	1.0	2.6	2.5	1.9	2.6	0.4	1.5	2.4	2.4	2.6	2.8	1.4	-2.8	-3.1	1.3	-2.3	2.6	2.1
Long-standing illness, disability or infirmity	2.0	3.0	10.6	2.5	-0.8	-2.1	-1.4	-0.2	-1.9	-2.4	-0.9	-2.0	-0.5	-1.0	-1.4	-1.6	-1.5	-1.4	-0.9	1.6	3.3	-2.1	1.7	-2.0	-1.7
Eye problems/disorders: Glaucoma	2.0	2.3	6.7	-0.7	-0.4	-1.7	-1.3	-0.7	-1.8	-1.4	-1.7	-1.6	-0.4	-0.0	-1.6	-2.2	-2.6	-1.6	-0.3	2.5	1.4	0.1	2.1	-1.6	-1.8
Mean Putamen Volume	1.9	2.1	3.4	-1.5	-1.8	-1.8	-1.0	-0.8	-1.4	-1.5	-1.5	-1.3	-1.8	-1.3	-1.1	-1.7	-1.8	-1.2	-1.2	1.8	0.7	-1.1	1.6	-1.3	-1.8
Impedance of leg (right)	1.9	9.0	16.4	-2.6	-0.5	-3.3	-3.0	0.7	-3.6	-3.6	-3.3	-3.5	0.2	-0.0	-3.6	-4.1	-4.0	-3.3	-0.3	3.8	2.1	-2.2	3.9	-3.5	-3.9
Hip circumference	1.9	8.3	16.9	2.6	1.0	3.0	3.5	-0.8	3.5	3.1	3.1	3.3	0.0	-0.3	3.4	3.9	4.0	2.7	0.5	-4.1	-1.0	3.0	-3.6	3.3	2.9
BMI	1.8	10.7	24.2	3.5	1.7	3.8	3.2	0.3	3.8	3.8	3.5	3.5	0.7	1.1	3.3	4.2	4.3	2.8	1.7	-4.1	-2.2	4.9	-3.8	3.5	3.1
Prospective memory result	1.8	2.2	5.0	-0.4	0.4	1.8	1.7	0.6	1.7	1.6	2.2	1.5	0.8	0.3	1.3	1.9	1.9	1.3	1.1	-1.8	-1.5	1.8	-1.9	1.5	1.1
Length of working week for main job	1.8	2.0	3.4	0.8	0.8	1.3	1.4	0.3	1.7	1.8	1.5	1.7	0.2	0.8	1.6	1.8	1.6	1.6	1.4	-1.5	-1.2	1.3	-1.7	1.7	1.6
Illnesses of siblings: Diabetes	1.8	2.2	4.0	-0.2	-0.7	-1.7	-1.5	-0.2	-1.5	-1.7	-1.9	-1.4	-1.0	-1.1	-1.4	-1.6	-1.7	-2.0	-1.0	2.0	1.9	-1.5	1.9	-1.4	-1.4
Pain type(s) experienced in last month: Hip pain	1.8	2.3	4.9	2.2	1.2	1.6	1.6	0.5	1.8	1.5	1.6	1.5	0.6	0.5	1.6	2.0	2.2	1.0	1.4	-1.9	1.1	1.3	-1.8	1.5	1.0
Diastolic blood pressure, automated reading	1.8	5.5	15.9	-0.8	0.6	-2.2	-3.9	0.1	-3.2	-1.9	-1.0	-3.3	0.4	0.8	-4.0	-2.5	-2.7	-3.9	0.6	2.0	-0.7	2.4	1.9	-3.3	-1.9
Worrier / anxious feelings	1.7	3.2	9.7	0.4	1.0	-2.1	-0.7	-2.7	-1.6	-1.9	-2.2	-1.5	-1.2	-1.2	-1.2	-1.8	-2.2	-2.1	-0.0	1.8	3.1	-2.5	1.8	-1.5	-1.6
Birth weight	1.7	3.7	13.6	0.9	0.9	1.5	3.7	-1.9	2.5	2.0	1.3	2.6	-0.7	0.7	3.1	2.0	1.7	2.6	0.5	-2.2	-0.3	0.4	-2.0	2.6	1.6
Shortness of breath walking on level ground	1.7	2.0	4.7	0.8	-0.5	1.5	1.7	0.8	1.7	1.9	1.8	1.9	0.5	-1.0	1.9	1.5	1.2	2.2	-0.3	-1.4	0.8	1.0	-1.5	1.9	1.6
Ever had hysterectomy (womb removed)	1.6	1.8	11.0	-2.2	-1.7	-1.1	-0.6	-1.9	-0.3	-0.5	-1.1	-0.4	-2.0	-3.3	-0.5	0.0	-0.1	-1.5	-2.2	0.1	0.8	0.3	0.5	-0.4	-0.8
Alcohol drinker status: Never	1.6	1.9	4.8	-1.0	0.3	1.5	1.2	-0.0	1.4	1.7	1.6	1.5	0.2	0.2	1.1	1.7	1.5	1.0	0.0	-1.7	-2.2	1.9	-1.9	1.5	1.7
Fasting Glucose	1.5	1.8	3.2	0.3	-0.8	-1.7	-1.6	-0.3	-1.8	-1.7	-0.7	-1.8	-1.5	-0.6	-1.7	-1.6	-1.6	-1.5	-0.3	1.3	0.5	-1.8	1.0	-1.8	-0.8
Relative age voice broke	1.5	2.3	8.6	-0.9	0.0	-1.9	-2.2	-0.7	-2.1	-1.5	-0.9	-2.1	-1.4	-0.4	-2.4	-1.5	-1.6	-2.9	0.3	1.2	-0.2	-0.2	1.3	-2.1	-0.7
Exposure to tobacco smoke at home	1.5	1.6	3.4	1.2	0.5	1.4	1.2	-0.2	1.5	1.3	1.7	1.4	0.2	-0.3	1.3	1.8	1.7	1.1	-0.1	-1.7	-1.6	0.9	-1.8	1.4	1.2
Emphysema/chronic bronchitis	1.5	1.7	11.2	-0.8	0.5	1.9	0.8	3.3	0.7	0.8	1.5	0.6	2.6	1.4	0.4	1.0	1.3	1.5	0.5	-1.1	0.1	1.1	-1.0	0.6	0.3
Neck or shoulder pain in last month	1.5	2.2	5.4	1.8	0.3	1.8	1.3	0.2	1.5	1.4	2.1	1.3	-0.0	0.4	1.3	1.9	2.2	1.0	1.0	-2.3	-1.0	1.3	-2.1	1.3	1.7
Sensitivity / hurt feelings	1.4	2.4	12.0	-0.5	-1.0	-1.6	-0.9	-0.6	-1.1	-1.4	-1.9	-1.0	-0.2	-2.4	-0.8	-1.5	-1.6	-1.1	-2.3	1.7	3.5	-1.3	1.6	-1.0	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.5	8.1	-1.2	1.0	2.6	2.4	-0.7	2.4	2.5	2.0	2.3	-0.2	1.5	2.3	2.4	2.6	1.8	2.0	-2.8	-2.8	1.4	-2.4	2.3	2.4
Hypothyroidism/myxoedema (self-reported)	1.4	2.8	7.7	1.4	0.5	-2.3	-1.4	-2.1	-1.7	-1.4	-1.9	-1.6	-1.0	-0.9	-1.5	-1.9	-2.3	-2.8	-0.1	1.9	2.4	-0.2	1.5	-1.6	-1.3
Medication: Seretide 50 evohaler	1.4	1.7	3.5	1.1	1.0	1.2	1.6	-0.2	1.4	1.4	1.2	1.3	-0.6	1.1	1.3	1.8	1.7	0.9	1.3	-1.9	-0.3	1.1	-1.7	1.3	1.4
Loneliness, isolation	1.4	1.9	3.7	1.7	-0.4	-1.5	-1.5	0.4	-1.6	-1.9	-0.9	-1.6	0.0	-0.7	-1.5	-1.6	-1.5	-1.0	-0.3	1.7	1.9	-1.0	1.6	-1.6	-1.6
Ever depressed for a whole week	1.4	1.7	5.3	0.3	-0.4	-1.2	-1.2	-0.6	-1.5	-1.8	-0.9	-1.7	-0.4	-1.0	-1.5	-1.1	-0.9	-1.6	-0.6	1.0	2.0	-2.3	1.2	-1.7	-1.4
Supplements: Calcium	1.4	1.5	5.6	-0.3	-1.6	-0.8	-0.8	1.1	-0.8	-1.5	-1.8	-0.9	0.5	-0.4	-0.8	-1.4	-1.0	-0.5	-0.7	1.4	1.6	-1.5	1.8	-0.9	-2.4
Heart disease (siblings)	1.4	1.7	2.9	-0.9	-0.5	-1.0	-1.4	1.4	-1.6	-1.5	-1.4	-1.6	0.8	-0.1	-1.5	-1.7	-1.5	-1.3	-0.5	1.6	1.7	-0.8	1.3	-1.6	-1.4
Body mass index (BMI)	1.3	5.6	12.2	2.8	1.8	2.3	2.1	-1.5	2.6	2.5	2.9	2.3	-0.0	0.2	2.3	3.2	3.1	1.5	1.0	-3.3	-1.4	3.5	-3.1	2.3	2.3
Age at last live birth	1.3	1.8	7.9	0.9	1.0	0.1	-1.3	1.7	-1.4	-1.4	-0.7	-1.4	2.8	1.7	-1.3	-1.5	-1.0	0.3	0.8	1.4	0.3	-2.1	1.5	-1.4	-0.7
Wears glasses or contact lenses	1.3	1.5	4.5	-0.5	-1.6	-1.7	-1.1	-1.2	-0.9	-1.2	-1.1	-1.0	-1.9	-2.1	-0.9	-0.7	-0.8	-1.3	-1.8	0.7	0.7	-1.8	0.8	-1.0	-0.5
Illnesses of father: High blood pressure	1.3	1.7	3.4	1.7	1.5	-1.3	-1.3	-0.9	-1.5	-0.9	-0.9	-1.4	-0.4	1.4	-1.3	-1.7	-1.9	-1.2	1.8	1.6	0.8	0.2	1.4	-1.4	-0.6
Myopia	1.3	1.8	6.4	0.5	-0.6	2.2	1.6	2.5	1.2	1.1	0.9	1.2	1.3	1.8	1.7	0.7	1.3	2.3	0.3	-0.5	-1.4	0.2	-0.7	1.2	1.3
Vitamin and mineral supplements	1.2	1.6	4.0	-0.3	-1.2	-1.6	-1.1	-0.1	-1.7	-1.2	-1.2	-1.5	-0.4	-0.7	-1.2	-1.8	-2.0	-0.9	-1.2	1.7	1.0	0.0	1.5	-1.5	-1.2
Severe depression (siblings)	1.2	1.4	6.1	-0.2	-1.4	-1.3	-1.1	0.5	-1.2	-1.3	-0.7	-1.4	-1.6	-1.0	-1.4	-0.5	-0.2	-1.2	-1.3	0.4	2.5	-1.3	0.5	-1.4	-0.7
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	6.6	2.0	2.5	1.5	1.0	1.3	0.8	0.9	1.1	0.8	1.2	2.4	0.8	1.2	1.2	0.7	2.6	-1.4	-0.3	0.9	-1.3	0.8	1.1
Pulse rate	1.2	2.0	7.8	-0.1	2.5	1.1	0.5	-0.3	0.9	1.0	1.6	0.7	-0.2	2.3	0.4	1.3	1.3	-0.3	2.8	-1.5	-2.2	1.7	-1.3	0.7	1.3
Lung cancer (father)	1.2	1.4	3.8	-0.9	-0.0	1.5	1.1	-0.4	1.6	0.9	1.3	1.3	-0.6	0.2	1.1	1.7	1.9	1.0	0.6	-1.9	-1.3	0.1	-1.4	1.3	1.0
Wheeze or whistling in the chest in last year	1.2	2.2	6.2	2.4	-0.5	0.7	1.0	-0.7	1.5	1.3	2.5	1.3	-0.0	-1.6	1.1	1.9	1.9	1.3	-1.1	-2.3	0.0	0.9	-2.0	1.3	1.6
Chest pain or discomfort	1.2	1.7	6.6	1.9	-0.7	-1.0	-1.2	-0.1	-1.2	-1.8	-0.7	-1.3	0.4	-1.2	-1.0	-1.2	-0.9	-0.8	-0.6	1.0	2.6	-1.7	1.4	-1.3	-1.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	3.6	1.9	0.5	0.8	1.4	-1.3	1.4	1.3	1.2	1.3	0.4	-0.7	1.3	1.5	1.3	1.4	0.2	-1.2	0.7	1.1	-1.0	1.3	1.0
Commuting to job workplace: Walk	1.2	1.3	3.3	0.8	-0.2	-1.6	-0.7	-0.9	-1.1	-1.3	-1.6	-1.0	-0.1	-0.2	-0.8	-1.8	-1.8	-0.8	-0.4	1.6	0.3	-0.8	1.7	-1.0	-1.6
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	4.4	1.8	-0.4	0.7	1.8	-0.2	1.9	0.8	-0.5	1.8	-0.6	-0.3	2.1	1.4	1.6	1.3	-0.3	-1.1	0.1	-1.7	-0.6	1.8	0.3
Blood Eosinophil Count	1.1	8.8	16.5	0.8	-1.4	-3.7	-2.4	-0.4	-3.3	-3.6	-3.5	-3.1	-0.6	-1.9	-2.4	-3.7	-3.7	-1.6	-2.0	4.0	3.8	-4.1	3.8	-3.1	-2.9
Blood White Count	1.1	8.0	14.5	-0.3	-1.6	-3.3	-3.5	1.4	-3.1	-3.8	-3.1	-3.1	-0.1	-1.0	-2.9	-3.3	-3.1	-1.7	-1.2	3.6	2.5	-3.7	3.8	-3.1	-3.7
Allergy or Eczema	1.1	3.0	16.8	1.6	-0.6	-1.7	-0.5	0.5	-1.7	-2.0	-1.1	-1.5	1.0	-0.9	-0.9	-2.0	-2.0	0.1	-0.8	2.2	4.1	-2.8	2.0	-1.5	-1.2
Supplements: Zinc	1.1	1.2	3.5	-1.1	-0.4	-1.1	-1.3	-0.4	-0.9	-1.3	-1.3	-1.1	-1.6	0.1	-1.1	-0.9	-0.6	-1.9	0.3	1.0	-1.0	-0.7	1.2	-1.1	-1.5
Medication: Lansoprazole	1.1	1.2	10.0	0.9	-2.1	0.2	-0.1	-0.6	0.2	0.2	0.8	-0.1	0.3	-3.2	0.1	0.7	0.9	0.3	-2.7	-0.7	0.8	0.2	-0.4	-0.1	0.5
Breastfed as a baby	1.1	1.4	5.0	-0.5	-0.6	-1.4	-0.7	-0.3	-1.0	-1.1	-1.5	-0.8	0.4	-1.7	-0.8	-1.5	-1.6	-0.7	-1.5	1.5	2.2	-0.9	1.3	-0.8	-1.2
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	6.5	0.4	-0.6	-0.8	-0.4	0.3	-0.4	-1.6	-2.5	-0.3	0.1	-0.1	-0.2	-1.6	-1.1	-0.3	-0.8	2.0	1.9	-2.2	2.1	-0.3	-2.5
Forced vital capacity (FVC), Best measure	1.1	4.2	7.5	-1.0	1.2	2.7	2.5	-0.4	2.3	2.3	1.9	2.2	0.4	1.8	2.4	2.3	2.6	1.9	1.9	-2.6	-2.4	0.5	-2.2	2.2	2.4
Handedness (chirality/laterality): Left-handed	1.1	1.3	3.2	1.8	0.6	0.7	1.3	-1.4	1.5	1.3	0.7	1.5	-0.6	0.1	1.3	1.3	1.4	1.2	0.6	-1.4	-0.0	0.1	-1.3	1.5	1.3
Supplements: Fish oil (including cod liver oil)	1.1	1.5	2.9	1.1	1.1	0.6	0.7	-1.5	1.3	1.3	0.9	1.3	-1.7	0.8	0.8	1.5	1.2	0.2	1.1	-1.6	-0.9	1.3	-1.7	1.3	1.2
Irritability	1.1	1.9	5.7	1.3	0.0	1.0	2.4	-1.6	1.8	1.1	0.4	1.6	-1.8	-0.7	2.1	1.8	1.8	1.1	0.3	-1.7	0.9	-0.3	-1.2	1.6	1.0
Schizophrenia (2018)	1.0	2.2	5.0	-1.0	-0.4	-1.5	-1.3	-0.8	-1.8	-1.7	-1.7	-1.7	0.3	-1.2	-1.4	-1.7	-2.1	-1.6	-0.6	2.2	0.7	-0.9	2.1	-1.7	-1.7
Crohns Disease (2012)	1.0	1.6	4.5	0.0	0.0	0.8	2.1	0.8	1.8	1.0	0.6	1.7	-0.1	0.0	2.0	1.7	1.8	1.4	-0.5	-1.7	1.2	0.1	-1.4	1.7	0.5
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.5	-0.6	-0.9	-1.0	-1.4	1.6	-1.2	-1.1	-1.2	-1.2	0.5	-0.7	-1.1	-1.0	-0.8	-0.6	-1.3	1.1	1.0	-0.6	1.2	-1.2	-0.9
Taking other prescription medications	1.0	1.5	10.2	2.4	-0.5	-1.3	-0.1	-1.2	-0.8	-1.2	-0.8	-0.8	-0.6	-1.3	-0.5	-1.0	-1.3	-0.5	-0.8	1.2	3.2	-0.7	1.0	-0.8	-1.3
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	5.0	-0.4	-2.0	-0.9	-0.4	-2.0	0.1	-0.2	-1.1	-0.0	-2.0	-2.2	-0.2	0.2	0.1	-1.2	-1.6	-0.3	-0.1	0.5	0.5	-0.0	-1.0
Medication: Levothyroxine sodium	1.0	1.7	5.2	1.3	0.3	-1.7	-1.3	-1.9	-1.6	-1.0	-1.0	-1.5	-0.4	-0.5	-1.3	-1.6	-1.9	-2.3	-0.2	1.5	1.2	0.3	1.0	-1.5	-0.5
Mouth/teeth dental problems: Loose teeth	1.0	1.1	3.0	1.0	-0.2	-1.4	-1.0	-1.3	-1.2	-1.3	-1.1	-1.1	-0.1	-0.6	-0.9	-1.3	-1.4	-0.5	-1.0	1.2	0.1	-1.7	1.2	-1.1	-0.8
Mean time to correctly identify matches	1.0	1.9	4.2	-1.1	-0.9	-1.8	-1.5	-1.2	-1.7	-1.3	-1.5	-1.5	-0.8	-0.7	-1.5	-1.8	-2.0	-1.6	-0.9	1.8	0.6	-0.1	1.7	-1.5	-1.1
Smoking status: Previous	1.0	1.5	10.1	1.7	-0.4	-0.6	-0.5	0.5	-0.6	-1.5	-1.3	-0.7	0.4	-0.4	-0.8	-1.1	-0.6	-0.1	-1.5	1.0	3.2	-1.9	1.2	-0.7	-1.9
Mood swings	1.0	1.9	4.6	0.6	0.0	-1.6	-1.2	-0.9	-1.5	-2.0	-0.8	-1.7	-1.0	-0.9	-1.5	-1.3	-1.2	-1.7	0.1	1.3	1.5	-2.1	1.6	-1.7	-1.5
Reaction Time	0.9	1.6	3.9	-0.2	-0.3	-1.6	-1.6	-1.5	-1.8	-1.3	-0.7	-1.7	-0.1	-0.6	-1.6	-1.7	-2.0	-1.3	-0.2	1.7	0.2	-0.1	1.6	-1.7	-0.7
HbA1C	0.9	1.0	4.8	-1.0	-2.2	-1.1	-1.1	0.1	-0.7	-0.7	-1.2	-0.7	-1.8	-0.5	-0.9	-0.6	-0.8	-1.5	-1.1	0.8	0.2	-0.2	0.8	-0.7	-0.6
Leg fat-free mass (left)	0.9	4.6	8.1	2.1	-0.3	2.1	2.5	-0.9	2.5	2.4	2.3	2.4	-0.3	-0.8	2.8	2.7	2.9	2.5	-0.5	-2.8	-1.0	1.4	-2.5	2.4	2.8
Average weekly fortified wine intake	0.9	1.0	2.8	-0.4	0.1	-0.7	-1.7	0.3	-1.3	-1.0	-0.9	-1.3	0.3	0.9	-1.6	-1.1	-1.1	-1.0	-0.1	1.1	-1.0	0.3	1.1	-1.3	-1.4
Leg predicted mass (left)	0.9	4.6	8.1	2.1	-0.3	2.1	2.4	-0.9	2.5	2.5	2.3	2.4	-0.2	-0.7	2.8	2.7	2.8	2.6	-0.4	-2.7	-1.1	1.5	-2.5	2.4	2.8
Mouth/teeth dental problems	0.9	1.3	3.3	-1.8	-1.3	-1.5	-1.1	-0.2	-1.2	-1.0	-1.3	-1.1	-0.8	-1.3	-0.9	-1.4	-1.4	-1.1	-1.1	1.2	0.2	-1.1	1.3	-1.1	-0.8
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	7.2	0.8	0.5	-1.2	-0.8	-1.1	-1.2	-1.0	-0.5	-1.0	0.4	-0.6	-1.1	-1.4	-1.6	-0.6	-0.4	1.4	2.7	-0.9	1.0	-1.0	-0.7
Pulse wave Arterial Stiffness index	0.9	1.1	2.1	-0.7	-0.0	-1.0	-1.4	-0.2	-1.4	-1.2	-0.4	-1.4	0.6	-0.6	-1.4	-1.2	-1.3	-1.3	-0.4	1.4	0.5	-0.9	1.1	-1.4	-0.8
Blood clot in the leg (DVT)	0.9	1.2	3.8	1.6	-0.4	0.5	1.6	-0.1	1.7	0.7	-0.8	1.7	-0.7	-0.2	2.0	1.1	1.3	1.1	-0.4	-0.8	0.2	-1.4	-0.4	1.7	0.1
Medication: Amlodipine	0.9	1.3	4.0	0.2	0.7	-1.4	-1.0	-1.9	-0.8	-0.8	-1.7	-0.7	-1.4	-0.5	-0.7	-1.0	-1.3	-2.0	0.2	1.2	2.0	-0.2	1.2	-0.7	-0.8
Arm fat-free mass (right)	0.9	4.8	9.5	1.3	-0.7	2.1	1.9	-0.1	2.5	2.6	2.7	2.3	-0.3	-0.7	2.3	2.9	3.0	2.4	-0.5	-3.1	-1.5	2.3	-2.8	2.3	3.0
Osteoporosis (self-reported)	0.9	1.1	7.2	0.2	-0.3	0.9	1.0	2.4	0.4	-0.1	-0.8	0.4	1.8	0.8	0.8	-0.3	0.2	1.3	-0.3	0.4	2.7	-0.4	0.6	0.4	-1.4
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	1.8	0.9	0.5	1.0	0.7	-0.8	0.9	0.8	1.2	0.8	-0.5	0.1	0.7	1.4	1.3	0.7	0.9	-1.1	-1.2	-0.1	-1.1	0.8	1.0
Serious illness, injury or assault to yourself	0.8	1.0	2.3	0.6	0.0	-0.9	-0.9	-0.2	-1.2	-1.1	-0.8	-1.1	0.3	-0.2	-0.8	-1.5	-1.4	-0.9	-0.2	1.3	1.5	-1.1	1.3	-1.1	-1.0
Stomach or abdominal pain in last month	0.8	0.9	2.2	1.0	-1.5	0.9	0.8	-0.1	0.9	0.6	1.2	0.7	-0.3	-1.2	0.7	1.3	1.5	1.3	-0.4	-1.3	0.3	-1.0	-0.9	0.7	1.0
Past tobacco smoking	0.8	1.5	6.9	-1.0	0.4	0.7	0.4	-0.9	0.7	1.8	1.2	0.9	-0.5	0.6	0.8	1.1	0.4	0.1	1.7	-0.8	-2.6	2.3	-1.2	0.9	2.2
Trunk fat-free mass	0.8	4.5	8.7	0.6	-1.4	1.9	1.7	-0.3	2.4	2.6	2.3	2.4	-0.4	-1.6	2.4	2.7	2.8	2.4	-1.6	-2.8	-1.6	1.8	-2.6	2.4	3.0
Noisy workplace	0.8	1.0	2.9	0.4	-0.3	1.1	0.8	0.1	0.9	1.2	1.7	0.9	0.2	-0.4	0.9	1.3	1.3	1.1	0.3	-1.3	-1.2	1.1	-1.3	0.9	1.4
Asthma	0.8	1.6	9.8	2.5	0.4	-1.9	-0.8	-1.4	-1.0	-1.0	-0.5	-0.9	-0.9	-1.1	-0.7	-1.1	-1.5	-1.0	-0.2	1.0	3.1	-1.1	0.7	-0.9	-0.4
Trunk predicted mass	0.8	4.3	8.3	0.6	-1.4	1.9	1.7	-0.3	2.4	2.5	2.3	2.3	-0.3	-1.5	2.3	2.6	2.7	2.4	-1.6	-2.7	-1.6	1.7	-2.5	2.3	2.9
Medication: Ventolin 100micrograms inhaler	0.8	1.1	7.1	2.0	0.9	-0.7	-0.5	1.5	-0.8	-0.8	-0.3	-0.7	0.8	0.8	-0.6	-0.9	-0.9	-0.2	1.0	0.9	2.7	-0.3	0.7	-0.7	-0.8
Medication: Allopurinol	0.8	1.0	2.4	0.6	-0.4	-1.1	-0.6	-1.2	-0.9	-0.9	-1.5	-0.9	-0.4	-1.4	-0.7	-1.1	-1.2	-1.3	-1.4	1.0	0.9	-0.5	1.0	-0.9	-1.3
Arm predicted mass (right)	0.8	4.3	7.9	1.3	-0.8	2.0	1.8	-0.2	2.4	2.5	2.5	2.3	-0.3	-0.7	2.2	2.7	2.8	2.3	-0.7	-2.8	-1.4	2.2	-2.6	2.3	2.8
Whole body fat-free mass	0.8	4.6	8.6	1.3	-0.8	2.0	2.0	-0.6	2.5	2.6	2.3	2.4	-0.3	-1.2	2.6	2.8	2.9	2.5	-1.1	-2.8	-1.4	1.7	-2.6	2.4	2.9
Leg fat-free mass (right)	0.8	4.2	7.6	2.0	-0.4	1.9	2.3	-0.7	2.5	2.4	2.0	2.4	-0.3	-0.8	2.8	2.6	2.6	2.6	-0.6	-2.5	-1.1	1.2	-2.3	2.4	2.7
Mineral and other dietary supplements	0.8	1.1	3.7	-0.4	-0.0	-0.5	-1.1	1.4	-1.4	-1.1	-0.4	-1.3	1.9	-0.5	-1.1	-1.4	-1.2	-0.4	-0.6	1.5	0.3	-0.6	1.3	-1.3	-0.7
Whole body water mass	0.8	4.8	8.9	1.3	-0.9	2.1	2.0	-0.5	2.6	2.6	2.4	2.5	-0.3	-1.2	2.6	2.9	3.0	2.5	-1.1	-2.9	-1.5	1.7	-2.7	2.5	3.0
Leg predicted mass (right)	0.8	4.1	7.6	2.0	-0.4	1.9	2.3	-0.7	2.5	2.3	2.0	2.4	-0.3	-0.7	2.8	2.5	2.6	2.6	-0.6	-2.4	-1.1	1.2	-2.2	2.4	2.7
Basal metabolic rate	0.8	4.4	8.1	1.6	-0.5	2.0	2.1	-0.6	2.5	2.5	2.3	2.4	-0.3	-1.0	2.5	2.8	2.9	2.4	-0.8	-2.8	-1.3	1.9	-2.6	2.4	2.7
Unable to work because of sickness or disability	0.8	1.1	2.6	1.1	-0.1	-1.3	-1.4	-0.0	-1.4	-1.6	0.1	-1.6	-0.2	-0.6	-1.2	-0.8	-0.7	-0.7	0.3	1.1	1.1	-1.3	1.1	-1.6	-0.6
Arm predicted mass (left)	0.8	4.1	8.6	0.9	-0.7	2.0	1.6	0.0	2.3	2.4	2.4	2.1	-0.3	-0.8	2.0	2.8	2.9	2.1	-0.9	-2.9	-1.6	2.2	-2.6	2.1	2.8
Alzheimer’s Disease (in mother)	0.7	0.8	1.5	-0.1	0.9	0.7	1.2	-0.1	1.1	1.2	0.8	1.2	0.4	0.1	1.1	1.0	0.7	1.2	1.0	-1.0	0.7	0.6	-1.0	1.2	1.2
Crohns Disease (2017)	0.7	1.5	4.2	0.4	-0.6	-0.0	1.8	-0.2	1.6	0.9	0.2	1.6	-0.9	-2.1	1.8	1.4	1.2	0.8	-1.7	-1.4	0.5	0.3	-1.4	1.6	0.5
Hayfever, allergic rhinitis or eczema	0.7	1.6	10.8	1.0	0.6	-1.1	0.3	0.5	-1.0	-1.3	-0.7	-0.8	1.2	-0.2	-0.2	-1.8	-1.5	0.4	0.3	1.6	3.3	-2.1	1.5	-0.8	-0.9
Multivitamins +/- minerals	0.7	0.9	2.4	0.3	1.1	1.3	0.5	0.0	1.2	1.0	1.1	1.0	0.5	0.4	0.7	1.4	1.6	0.3	0.9	-1.4	-0.4	0.5	-1.2	1.0	1.1
High blood pressure (mother)	0.7	1.0	2.9	0.0	0.6	-0.7	-1.4	-0.3	-1.2	-0.9	-1.0	-1.3	-0.1	0.5	-1.3	-1.0	-0.9	-1.7	0.1	1.0	-1.7	-0.0	1.0	-1.3	-0.8
Depression (self-reported)	0.7	0.8	2.5	0.8	-0.3	-0.9	-0.5	-1.1	-1.0	-1.1	-0.8	-0.9	-0.5	-0.9	-0.5	-0.9	-1.1	-0.7	0.1	1.3	0.3	-1.6	1.2	-0.9	-0.4
Worry too long after embarrassment	0.7	1.1	6.0	0.2	-0.5	-1.1	-0.3	-2.4	-0.7	-0.6	-0.5	-0.7	-0.6	-2.3	-0.6	-0.7	-0.8	-0.7	-1.2	0.6	2.3	-0.7	0.5	-0.7	-0.3
Number of children fathered	0.7	0.8	3.6	0.1	-0.7	-1.4	-0.8	-1.9	-0.5	-0.4	-0.6	-0.6	-1.9	-1.5	-0.6	-0.3	-0.5	-1.1	-1.2	0.1	0.1	-0.3	0.1	-0.6	-0.1
Pulse rate, automated reading	0.7	2.4	5.4	-0.4	1.7	1.6	1.7	0.5	1.6	1.7	2.2	1.5	1.1	1.2	1.2	1.8	1.6	1.2	1.6	-1.9	-0.7	2.3	-1.8	1.5	1.5
Number of full sisters	0.7	0.9	2.9	-0.5	0.0	-1.0	-1.4	-0.9	-1.1	-1.2	-0.3	-1.2	-1.0	-0.8	-1.0	-0.7	-0.7	-1.7	-0.7	0.6	0.5	-1.1	0.5	-1.2	-0.6
Family relationship satisfaction	0.7	0.8	4.4	0.1	-0.7	-0.7	-1.3	2.1	-1.0	-0.9	-0.5	-0.9	0.0	0.2	-1.0	-1.0	-0.8	-0.4	-0.7	0.8	1.4	-0.7	0.9	-0.9	-0.7
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.6	0.4	-0.1	0.4	0.8	-1.9	0.8	0.9	1.6	0.8	-0.8	-0.4	0.8	1.2	0.9	1.0	0.6	-0.8	-0.5	0.4	-1.0	0.8	1.1
Qualifications: nursing, teaching	0.7	1.1	6.3	0.1	-1.4	-1.2	-0.8	-1.4	-0.6	-1.1	-1.0	-0.7	-1.1	-1.5	-0.8	-0.5	-0.3	-0.5	-1.1	0.5	0.0	-2.5	0.9	-0.7	-0.6
Asthma (self-reported)	0.7	1.5	8.6	2.4	0.6	-1.8	-0.7	-1.3	-1.0	-1.0	-0.4	-0.8	-0.8	-0.9	-0.7	-1.1	-1.5	-1.0	-0.1	0.9	2.9	-1.0	0.7	-0.8	-0.5
Arm fat-free mass (left)	0.7	3.6	7.7	0.8	-0.8	1.7	1.4	-0.2	2.1	2.3	2.2	1.9	-0.4	-1.1	1.9	2.6	2.8	1.9	-1.1	-2.8	-1.3	2.1	-2.5	1.9	2.6
Number of operations (self-reported)	0.7	1.1	5.5	1.8	-0.9	-0.1	1.0	-0.2	0.9	-0.2	-0.3	0.8	-0.8	-1.6	1.1	0.5	0.8	0.6	-0.8	-0.5	2.3	-2.0	-0.3	0.8	-0.3
Fractured/broken bones in last 5 years	0.7	0.9	3.0	0.9	-0.4	1.4	0.8	1.0	0.6	1.0	1.7	0.6	1.6	-0.1	0.5	0.9	1.0	1.6	-0.1	-0.9	-0.5	0.9	-0.8	0.6	1.1
Alzheimer’s Disease (including proxy)	0.6	0.8	1.8	0.0	1.3	0.9	0.7	-0.0	0.8	1.0	1.3	0.8	0.8	0.6	0.7	1.0	0.9	1.1	1.3	-1.3	-0.1	0.5	-1.2	0.8	1.3
Verbal and Numeric Reasoning (VNR)	0.6	1.4	7.3	0.5	-0.9	-1.0	-0.5	-0.8	-0.4	-1.5	-2.2	-0.5	-0.5	-1.2	-0.1	-0.8	-0.7	-1.1	-1.8	1.2	1.1	-2.7	1.6	-0.5	-1.2
Hearing difficulty/problems: Yes	0.6	0.8	3.6	0.3	-0.8	1.2	0.6	1.8	1.0	0.5	1.1	1.0	0.8	0.1	0.7	0.9	1.1	1.9	0.0	-0.9	0.2	-0.4	-0.8	1.0	0.0
Relative age of first facial hair	0.6	1.3	3.8	-0.7	0.4	-1.2	-1.6	-0.7	-1.5	-1.1	-0.4	-1.7	-0.6	0.0	-1.8	-0.8	-0.8	-2.0	0.9	0.8	-1.2	-0.6	1.0	-1.7	-0.1
Diabetes (father)	0.6	0.8	2.8	0.5	-0.8	0.3	0.9	0.3	0.8	1.2	0.7	1.0	-0.1	-1.2	1.0	0.5	0.2	0.8	-1.0	-0.5	1.3	1.7	-0.8	1.0	0.8
Hand grip strength (right)	0.6	1.7	5.6	-1.7	-0.7	-1.6	-2.2	-0.5	-1.4	-0.8	-0.9	-1.4	-2.3	-0.1	-1.8	-1.1	-1.1	-2.4	-0.1	0.5	-1.0	0.1	0.7	-1.4	-0.6
Supplements: Glucosamine	0.6	0.8	3.7	-1.4	-0.6	0.3	0.8	-0.9	0.9	0.8	0.3	0.8	-1.9	-0.5	0.6	1.3	1.0	-0.0	-0.4	-1.3	-0.5	0.9	-1.1	0.8	0.5
Number of incorrect matches in round	0.6	1.0	2.4	-0.3	0.0	1.5	0.7	1.1	1.1	1.0	1.3	1.0	0.5	0.6	0.7	1.4	1.5	1.2	0.9	-1.2	-0.5	0.6	-1.1	1.0	1.0
Hearing difficulty/problems with background noise	0.6	0.9	5.2	0.5	0.3	1.2	0.9	2.3	1.0	0.4	0.8	0.9	0.8	0.6	0.8	0.8	1.1	1.2	1.0	-0.6	1.2	0.2	-0.6	0.9	-0.1
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	3.6	1.9	-0.7	0.3	0.5	0.4	0.5	0.0	1.3	0.2	0.2	-1.6	0.5	0.8	1.0	0.5	-0.7	-0.9	1.3	-0.7	-0.8	0.2	-0.1
Allergy	0.6	1.4	14.7	-2.1	-0.4	0.6	-1.0	-0.5	0.2	0.7	0.3	0.0	-1.1	0.8	-0.6	0.9	0.7	-0.9	0.2	-0.8	-3.8	2.1	-0.6	0.0	0.5
Neuroticism score	0.6	1.3	9.3	1.7	0.5	-0.9	-0.1	-1.7	-0.7	-1.1	-0.6	-0.8	-0.7	-0.9	-0.6	-0.7	-0.8	-0.9	0.4	0.7	3.0	-1.5	0.8	-0.8	-1.0
Falls in the last year	0.6	0.8	3.2	1.0	-0.5	-0.1	-0.9	1.8	-1.0	-1.1	-0.2	-1.1	1.5	0.1	-0.9	-0.8	-0.4	-0.5	-0.6	0.6	1.4	-0.3	0.7	-1.1	-1.0
Hair/balding pattern: Pattern 3	0.6	0.9	1.8	0.3	-0.9	1.0	1.2	0.4	1.3	1.0	0.8	1.3	-0.0	0.1	1.3	1.1	1.1	1.1	-0.7	-0.9	0.2	0.6	-1.1	1.3	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	5.0	-0.1	1.9	0.9	0.9	-0.1	0.4	0.6	0.6	0.4	0.2	2.2	0.2	0.5	0.5	0.0	2.0	-0.7	0.4	0.4	-0.5	0.4	0.7
Glaucoma (self-reported)	0.6	0.8	2.3	-1.5	-1.3	-0.3	0.5	-0.2	0.1	0.1	-1.1	0.4	-0.1	-0.4	0.3	-0.9	-1.2	0.4	-1.3	1.2	1.5	1.1	0.8	0.4	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.7	-1.1	-1.6	0.3	0.9	-0.1	0.9	1.0	0.4	1.0	-1.4	-0.7	0.9	0.7	0.6	0.5	-0.7	-0.5	-1.0	0.1	-0.8	1.0	0.9
Migraine (self-reported)	0.6	0.7	2.2	0.3	0.6	-0.1	-0.8	1.2	-1.0	-0.5	-0.1	-0.8	0.9	1.5	-1.0	-1.1	-1.1	-0.3	0.6	1.1	1.3	0.3	0.7	-0.8	-0.6
Medication: Ibuprofen	0.6	0.7	2.9	-0.6	1.4	1.0	0.8	0.1	0.5	0.8	1.0	0.4	0.1	1.7	0.4	0.9	0.9	-0.1	1.5	-1.0	-0.4	0.7	-0.9	0.4	0.9
Comparative height size at age 10	0.6	3.0	7.2	-1.6	-2.7	-2.1	-1.1	-0.5	-1.6	-1.6	-2.4	-1.5	-1.1	-1.7	-1.1	-1.7	-1.7	-1.2	-2.6	1.7	1.6	-1.6	2.0	-1.5	-1.7
Suffer from ‘nerves’	0.6	0.9	2.8	1.7	1.2	1.0	1.1	0.8	0.6	0.6	1.1	0.7	1.5	1.2	0.7	0.2	0.2	1.1	1.7	-0.1	1.1	0.5	-0.4	0.7	0.1
Knee pain experienced in last month	0.6	1.0	3.1	0.3	-0.4	1.1	1.0	0.2	1.0	0.8	1.1	0.8	-0.5	-0.1	0.8	1.5	1.8	0.9	-0.4	-1.7	0.5	0.1	-1.6	0.8	1.4
Miserableness	0.6	1.0	4.4	0.4	0.3	-0.5	-0.7	0.1	-1.1	-1.4	-0.7	-1.2	0.3	-0.2	-0.9	-1.0	-0.7	-0.5	0.3	0.9	2.1	-1.8	1.1	-1.2	-1.1
Commuting to job workplace: Public transport	0.6	0.7	3.5	-0.3	-1.4	-0.8	-1.0	0.3	-0.7	-0.5	-1.1	-0.6	-0.2	-1.5	-0.6	-0.9	-0.9	-0.6	-1.9	0.9	0.3	0.0	0.8	-0.6	-0.4
Alcohol drinker status: Previous	0.6	0.7	4.8	-0.1	-0.0	-0.6	-0.4	1.2	-0.5	-0.7	-1.0	-0.5	0.8	-0.0	-0.4	-0.9	-0.7	-0.6	-0.3	1.2	2.2	0.0	0.9	-0.5	-1.1
Neuroticism (Nagel 2018)	0.5	1.2	11.4	0.5	0.2	-0.9	-0.4	-0.5	-0.8	-1.1	-1.0	-0.9	-0.4	-1.1	-0.8	-0.7	-0.8	-1.2	0.1	0.8	3.4	-0.9	0.9	-0.9	-1.2
Worry (Nagel 2018)	0.5	1.0	5.7	1.1	1.7	-0.5	0.1	-0.8	-0.6	-0.9	-0.7	-0.5	0.3	0.7	-0.5	-0.7	-0.9	-0.8	1.8	0.8	2.4	-1.3	0.8	-0.5	-1.0
Primary Biliary Cirrhosis	0.5	0.7	5.6	1.3	1.2	-0.0	-0.3	1.7	-0.4	-0.5	-0.2	-0.3	0.5	2.4	-0.3	-0.4	-0.2	0.3	1.1	0.5	-0.4	-0.7	0.1	-0.3	-0.5
Blood Platelet Count	0.5	6.0	12.5	2.6	-0.6	-3.1	-2.9	-0.2	-2.3	-3.1	-3.5	-2.2	-1.9	0.0	-2.0	-2.6	-2.9	-2.3	-1.1	3.3	1.4	-2.8	3.2	-2.2	-3.0
Height	0.5	10.3	20.0	-3.2	-4.5	-3.4	-2.1	-0.2	-3.2	-3.5	-4.0	-3.0	-1.3	-3.4	-2.3	-3.5	-3.3	-2.0	-3.8	3.6	2.8	-4.5	4.0	-3.0	-2.7
Lung FEV1/FVC ratio	0.5	2.5	12.3	-2.1	-0.5	1.6	0.9	0.9	1.4	2.1	1.2	1.4	-0.3	0.0	0.6	1.7	1.7	0.8	-0.0	-1.9	-2.1	3.5	-2.0	1.4	1.3
Number of treatments/medications taken	0.5	1.0	4.5	1.4	-0.6	-1.1	-0.6	-0.2	-0.8	-1.0	-0.8	-0.8	-0.6	-1.4	-0.8	-0.7	-0.8	-0.9	-0.8	1.0	2.1	0.0	0.8	-0.8	-1.3
Qualifications: CSEs or equivalent	0.5	0.6	1.9	0.2	0.3	-1.1	-1.4	-1.3	-0.6	-0.5	-0.7	-0.7	-0.9	-0.5	-1.1	-0.4	-0.6	-1.1	0.2	0.6	-0.6	0.6	0.8	-0.7	-0.8
Pain all over the body in last month	0.5	0.6	2.8	-0.6	-0.8	-0.3	0.2	-1.5	0.4	0.6	0.7	0.3	-1.6	-0.7	-0.0	0.8	0.3	-0.4	-0.4	-0.8	-0.4	1.7	-0.6	0.3	0.2
Weight	0.5	2.4	4.5	1.9	0.2	1.3	1.7	-1.1	1.8	1.7	1.7	1.6	-0.2	-0.8	1.9	2.1	2.1	1.5	-0.3	-2.1	-0.5	1.9	-1.8	1.6	1.7
Arm fat mass (right)	0.5	2.0	4.9	2.2	0.8	1.1	1.5	-1.5	1.5	1.3	1.7	1.3	-0.3	-0.6	1.5	1.9	1.8	0.8	0.1	-2.0	-0.2	2.0	-1.7	1.3	1.2
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.6	0.6	0.6	0.9	0.3	0.4	0.6	0.7	1.0	0.6	-0.2	1.6	0.4	0.8	0.9	0.8	1.1	-0.7	-0.5	0.3	-0.8	0.6	1.0
Age at first live birth	0.5	0.9	6.4	-0.0	1.0	0.5	-0.2	1.0	-0.5	-0.8	-0.9	-0.5	2.5	0.9	-0.4	-0.8	-0.5	0.5	0.7	0.9	0.3	-1.9	1.3	-0.5	-0.6
Pulse wave peak to peak time	0.5	0.6	1.3	0.6	-0.2	0.6	1.0	0.2	1.1	0.9	0.1	1.1	-0.6	0.4	1.1	0.8	0.9	1.1	0.2	-1.0	-0.2	0.7	-0.7	1.1	0.4
Had major operations	0.5	0.6	4.2	-0.3	-1.4	0.2	0.5	0.4	0.5	-0.5	-0.5	0.4	-0.1	-1.4	0.6	0.3	0.6	0.3	-1.2	0.1	1.2	-2.0	0.3	0.4	-0.5
Average weekly red wine intake	0.5	0.7	4.0	-1.4	-0.4	-0.5	-0.4	-0.7	-0.5	-0.5	-1.6	-0.5	-2.0	-0.0	-0.4	-0.2	-0.2	-1.9	-0.5	0.4	0.2	-0.2	0.6	-0.5	-0.3
Friendships satisfaction	0.5	0.7	1.7	1.2	0.5	0.7	0.0	0.7	0.6	0.8	1.2	0.6	-0.6	0.6	0.2	1.0	0.9	0.6	1.0	-1.3	-0.4	-0.0	-1.1	0.6	1.2
Guilty feelings	0.5	0.8	4.6	0.2	-1.0	-0.6	-0.8	-0.4	-0.7	-0.9	-0.6	-0.7	-0.2	-1.3	-0.9	-0.7	-0.7	-0.7	-1.1	0.9	2.1	-0.6	0.9	-0.7	-1.1
Ever smoked	0.5	0.8	3.2	-0.1	-0.3	-0.5	-0.2	0.5	-0.6	-1.3	-0.7	-0.8	0.6	-1.1	-0.8	-0.7	-0.2	-0.2	-1.7	0.2	1.6	-1.5	0.6	-0.8	-1.8
Risk taking	0.5	0.7	5.0	1.8	0.3	0.6	-0.0	2.2	0.0	0.1	0.8	0.1	1.4	1.3	0.1	0.0	0.2	0.9	0.8	-0.0	0.2	-1.1	-0.2	0.1	0.6
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.4	0.6	-0.1	0.4	1.0	-1.2	1.0	0.9	0.7	0.9	-0.6	-0.9	0.8	1.0	0.7	0.6	-0.0	-0.9	0.2	0.9	-0.8	0.9	0.4
Leg fat mass (left)	0.5	2.0	6.3	2.3	1.3	1.1	1.3	-1.3	1.4	1.3	1.9	1.2	0.1	-0.3	1.2	1.8	1.7	0.6	0.4	-1.9	0.2	2.5	-1.8	1.2	1.2
Prostate Cancer	0.4	0.6	4.6	-2.2	-1.2	-0.7	-0.1	-0.8	0.1	-0.2	-0.9	0.1	-1.6	-0.8	0.2	-0.1	-0.1	-0.3	-0.7	0.1	0.7	-0.3	0.4	0.1	-0.2
Respiratory disease	0.4	0.8	8.3	1.7	-0.4	-0.7	-0.5	0.0	-0.6	-0.9	0.2	-0.6	0.1	-0.9	-0.5	-0.5	-0.5	-0.2	-0.7	0.3	2.9	-1.4	0.3	-0.6	-0.3
Chronotype (morning person)	0.4	1.0	6.8	2.6	2.6	-0.1	0.6	-0.6	0.2	0.2	0.3	0.3	0.5	1.4	0.4	-0.0	-0.4	0.4	1.9	0.1	1.4	0.2	-0.1	0.3	0.4
Hair Pigment	0.4	12.7	24.3	0.6	1.2	4.4	3.8	2.1	4.1	4.2	4.6	3.9	1.2	1.4	3.5	4.5	4.8	3.8	1.2	-4.9	-2.1	3.9	-4.7	3.9	3.8
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.7	1.3	1.2	0.5	0.7	0.7	0.5	0.3	0.8	0.6	1.2	0.9	0.7	0.3	0.2	1.1	0.9	0.0	0.2	0.1	-0.3	0.6	0.3
Medication for hormone replacement therapy	0.4	0.4	2.7	0.7	0.7	0.4	0.2	-0.2	-0.0	-0.1	0.9	-0.2	-0.5	0.8	-0.1	0.6	0.7	0.1	1.7	-0.8	0.4	-1.2	-0.5	-0.2	0.7
Pack years adult smoking proportion	0.4	0.6	3.2	-0.4	-0.7	0.1	0.2	-0.6	0.7	0.9	0.4	0.7	-0.2	-1.4	0.6	0.5	0.4	0.0	-0.9	-0.6	-1.8	1.8	-0.6	0.7	0.5
Current tobacco smoking	0.4	0.7	2.7	-0.6	0.3	0.7	0.8	1.7	0.5	0.6	0.7	0.6	0.3	1.2	0.8	0.4	0.5	0.5	0.3	-1.1	-1.6	0.6	-1.0	0.6	0.6
Fed-up feelings	0.4	0.8	2.6	1.6	0.3	0.7	0.8	-0.2	1.1	0.9	1.2	1.0	-0.4	0.2	0.9	1.1	1.0	0.5	0.8	-1.1	0.3	1.4	-0.9	1.0	0.3
Age when periods started (menarche)	0.4	1.0	5.5	-2.4	-2.0	-0.8	-1.2	0.0	-0.7	-0.3	-0.8	-0.5	-1.3	-1.2	-0.8	-0.8	-1.0	-0.6	-0.5	1.0	-1.1	-0.4	1.1	-0.5	0.2
Hair/balding pattern: Pattern 2	0.4	0.5	1.3	1.1	-0.2	0.6	0.9	0.5	0.7	0.7	0.8	0.6	-0.4	-0.2	0.8	0.9	1.1	0.7	-0.6	-0.9	0.5	0.5	-1.0	0.6	0.6
Qualifications: None of the above	0.4	0.9	5.1	-0.3	0.2	0.6	0.1	0.1	0.3	1.1	2.0	0.2	-0.3	0.2	0.2	1.0	0.6	0.2	0.7	-1.2	-1.1	2.3	-1.6	0.2	1.4
Fluid intelligence score	0.4	0.8	3.1	0.7	0.1	-0.7	-0.7	-0.4	-0.5	-1.1	-1.8	-0.5	0.4	-0.2	-0.3	-0.9	-0.7	-0.9	-1.0	1.1	0.6	-1.7	1.4	-0.5	-1.0
Alcohol intake versus 10 years previously	0.4	0.6	3.3	-0.1	0.6	0.8	-0.1	1.0	0.1	0.7	1.5	-0.0	0.5	0.7	-0.3	0.7	0.7	0.5	1.0	-0.8	-0.2	1.8	-0.9	-0.0	0.6
Qualifications: A levels/AS levels or equivalent	0.4	1.0	3.7	0.1	-0.8	-0.5	-0.8	1.2	-0.4	-1.2	-1.5	-0.4	0.5	-0.5	-0.6	-1.1	-0.6	-0.3	-1.2	1.0	0.7	-1.8	1.2	-0.4	-1.9
Mouth/teeth dental problems: Dentures	0.4	0.6	1.6	0.7	0.7	0.2	0.7	-1.1	0.9	0.6	0.9	0.8	-0.4	-0.2	0.5	1.1	1.0	0.3	0.0	-1.3	0.1	1.1	-1.2	0.8	0.4
Standing height	0.4	4.1	11.8	-1.9	-3.4	-2.1	-0.9	0.2	-1.6	-1.7	-2.6	-1.3	-0.6	-2.6	-0.8	-2.2	-2.1	-0.0	-3.0	2.3	1.9	-3.1	2.6	-1.3	-1.2
Chronic bronchitis/emphysema (mother)	0.4	0.5	4.6	2.1	0.2	-0.4	-0.4	-0.4	-0.6	-0.4	-0.1	-0.7	-0.2	0.2	-0.3	-0.1	-0.3	-0.8	-0.1	0.3	1.6	-0.0	0.3	-0.7	0.4
Exposure to tobacco smoke outside home	0.4	0.6	2.9	1.6	-0.1	-0.0	-0.1	-1.7	0.6	0.5	0.7	0.5	-1.2	-0.7	0.3	1.0	0.7	-0.4	-0.1	-0.8	-0.6	0.5	-0.5	0.5	0.8
Comparative body size at age 10	0.4	1.1	7.5	0.6	2.7	0.5	0.7	-0.3	0.2	0.2	-0.4	0.2	0.9	2.3	0.2	0.1	-0.1	0.1	2.0	0.0	-1.0	1.4	0.1	0.2	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	3.6	1.4	-0.0	-0.8	0.3	-1.9	-0.0	-0.5	-0.3	0.0	-0.7	-1.1	0.1	-0.3	-0.5	0.2	0.0	0.7	0.5	-1.1	0.7	0.0	-0.6
Leg fat mass (right)	0.4	1.7	6.0	2.1	1.3	1.0	1.2	-1.5	1.2	1.2	1.7	1.0	0.1	-0.4	1.0	1.7	1.6	0.4	0.4	-1.9	0.1	2.5	-1.6	1.0	1.0
Alcohol intake frequency.	0.4	1.0	3.6	0.9	1.6	1.5	0.9	0.7	0.6	0.8	1.1	0.6	1.9	0.7	0.7	1.0	0.9	1.0	1.7	-0.3	0.8	1.1	-0.5	0.6	0.6
Leg pain on walking	0.4	0.5	2.8	-0.3	-1.5	-0.5	-0.6	-0.3	-0.0	-0.2	-0.1	-0.1	-1.3	-1.4	-0.2	0.2	0.4	-0.3	-1.7	-0.1	0.3	-0.5	-0.2	-0.1	0.1
Arm fat mass (left)	0.4	1.7	5.7	2.4	0.9	1.2	1.4	-1.1	1.4	1.1	1.6	1.1	0.2	-0.3	1.4	1.7	1.7	0.9	0.3	-1.8	-0.1	1.9	-1.5	1.1	1.1
Financial situation satisfaction	0.4	0.5	2.3	-1.5	-1.0	0.1	-0.9	1.0	-0.6	-0.1	0.1	-0.6	-0.2	-0.2	-0.8	-0.0	0.1	-0.8	-1.0	-0.4	-1.1	-0.9	-0.1	-0.6	0.7
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.5	-0.0	-1.6	0.0	0.4	0.3	0.4	-0.2	-0.1	0.3	-1.5	-1.1	0.4	0.4	0.6	0.3	-1.0	-0.3	0.6	-1.5	-0.2	0.3	-0.1
Depressed Affect (Nagel 2018)	0.3	0.6	3.4	1.4	0.5	-0.7	-0.6	-0.4	-0.8	-1.0	0.0	-0.9	-0.1	-0.6	-0.8	-0.5	-0.6	-1.0	0.6	0.5	1.8	-0.2	0.5	-0.9	-1.0
Heel T-Score	0.3	2.2	12.7	1.1	0.7	-0.4	-2.0	0.0	-1.5	-2.0	0.1	-1.8	0.5	1.8	-1.7	-0.9	-0.4	-0.9	1.2	0.3	-2.2	-3.6	0.8	-1.8	-0.8
Neuroticism	0.3	0.7	8.3	0.3	0.3	-0.4	-0.2	-0.9	-0.6	-0.8	-0.3	-0.7	-0.2	-0.8	-0.6	-0.6	-0.6	-0.9	0.2	0.4	2.9	-0.7	0.5	-0.7	-0.8
Hand grip strength (left)	0.3	0.8	2.8	-1.3	-0.1	-1.1	-1.5	-0.7	-0.8	-0.3	-0.6	-0.9	-1.3	-0.1	-1.2	-0.6	-0.6	-1.7	-0.1	0.0	-1.6	0.6	0.3	-0.9	-0.3
Average weekly spirits intake	0.3	0.4	3.7	-0.7	-0.7	-0.6	0.1	-0.9	0.1	0.3	-0.2	0.1	-1.9	-0.4	0.1	0.4	0.1	-0.4	-0.8	-0.4	-0.4	0.4	-0.5	0.1	0.5
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.7	1.3	0.2	-0.2	0.3	0.3	0.0	-0.6	-0.3	0.0	0.6	0.1	0.2	-0.4	-0.2	0.8	-0.1	0.5	1.3	-1.1	0.7	0.0	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	2.5	1.3	0.6	0.6	-0.1	1.2	-0.2	-0.3	0.8	-0.2	1.6	0.3	0.1	-0.1	0.2	0.5	0.6	0.4	0.1	0.1	0.1	-0.2	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	6.3	1.5	1.1	0.5	-0.0	-0.5	0.3	0.0	1.2	0.1	0.5	0.3	0.1	0.6	0.7	0.0	0.8	-1.0	-2.5	-0.8	-0.9	0.1	0.6
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	2.1	-1.3	-0.7	0.4	-0.5	0.4	-0.3	-0.0	-0.3	-0.3	1.4	-0.7	-0.5	-0.1	-0.2	0.2	-1.0	0.3	0.9	-0.3	0.5	-0.3	0.2
Chronic bronchitis/emphysema (father)	0.3	0.3	2.9	1.6	0.1	-0.1	-0.0	-0.2	-0.1	-0.5	-0.0	-0.2	0.0	-0.4	-0.0	0.0	-0.0	-0.0	-0.2	0.1	1.7	-0.6	0.2	-0.2	-0.3
Alcohol usually taken with meals	0.3	0.5	3.5	-0.6	1.2	0.0	0.1	0.4	-0.2	-0.4	-0.2	-0.3	0.2	1.5	-0.4	-0.4	-0.3	-0.7	1.9	0.4	0.4	-0.1	0.4	-0.3	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	5.9	1.6	1.0	0.6	-0.3	0.1	0.1	-0.0	1.4	0.0	1.0	0.3	-0.1	0.4	0.6	0.2	0.5	-0.8	-2.4	-1.0	-0.9	0.0	0.8
Time employed in main current job	0.3	0.4	2.6	-0.5	-0.1	0.0	0.1	-1.6	0.0	0.9	0.3	0.1	-0.6	-0.7	0.1	0.5	0.1	0.2	-0.3	-0.4	-0.7	0.7	-0.6	0.1	1.4
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	2.0	1.2	-0.0	0.0	-0.5	1.4	-0.8	-0.7	-0.1	-0.8	1.2	0.3	-0.6	-0.7	-0.4	-0.3	-0.1	0.7	0.5	-0.2	0.6	-0.8	-0.5
Tense / ‘highly strung’	0.3	0.4	3.0	0.9	0.6	0.3	0.3	0.8	-0.2	-0.2	0.4	-0.2	0.4	0.9	-0.2	-0.1	-0.1	0.6	1.3	-0.3	1.7	-0.9	-0.1	-0.2	0.4
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.1	-0.4	-0.3	0.8	0.2	-0.0	0.3	0.6	0.8	0.2	-0.4	-0.2	0.0	0.7	0.7	0.1	0.1	-1.1	-0.7	0.7	-0.9	0.2	0.8
Leg fat percentage (right)	0.3	1.0	7.3	1.8	1.9	0.4	0.5	-1.1	0.4	0.5	1.1	0.2	0.1	0.3	0.1	0.9	0.7	-0.6	1.0	-1.1	0.8	2.7	-1.0	0.2	-0.0
Number of full brothers	0.3	0.4	1.6	1.3	-0.9	0.4	0.3	0.7	0.5	0.2	0.2	0.5	-0.8	0.1	0.6	0.5	0.7	0.4	-0.8	-0.7	0.7	-1.1	-0.7	0.5	0.7
Health satisfaction	0.3	0.4	1.5	1.2	0.7	0.6	0.7	0.7	0.5	0.2	1.1	0.4	0.4	0.3	0.5	0.6	0.7	0.6	0.4	-0.9	0.7	-0.2	-0.7	0.4	0.2
Eye problems/disorders: None of the above	0.3	0.4	2.0	-0.7	0.5	0.5	0.0	0.3	0.0	0.5	0.6	0.1	-0.1	1.3	0.0	0.2	0.2	-0.1	0.9	-0.4	-1.0	1.4	-0.4	0.1	0.4
Medication: Omeprazole	0.3	0.4	1.2	0.7	0.1	0.2	1.1	-1.0	1.0	0.6	0.2	1.0	-0.7	-0.1	0.9	0.5	0.4	1.0	0.2	-0.4	0.1	0.0	-0.2	1.0	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	3.8	0.1	-0.3	-0.7	0.3	-0.9	0.3	0.2	-0.5	0.4	-1.9	-0.1	0.6	-0.1	-0.4	-0.2	-0.3	0.3	0.3	0.9	0.1	0.4	-0.2
Overall health rating	0.3	0.5	4.2	2.0	0.6	0.3	-0.2	1.1	-0.5	-0.5	0.9	-0.6	1.9	-0.1	-0.3	-0.3	-0.1	0.2	0.1	0.2	0.0	0.3	0.1	-0.6	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.2	0.6	-1.1	-0.1	0.8	-1.5	0.6	0.6	0.7	0.6	-0.4	-1.4	1.0	0.5	0.4	0.8	-0.5	-0.4	0.1	-0.4	-0.3	0.6	1.0
Arm fat percentage (left)	0.3	1.0	7.4	2.7	1.7	0.6	1.0	-1.3	0.7	0.4	1.0	0.5	0.4	0.2	0.9	0.9	0.8	0.2	0.9	-0.9	0.6	1.3	-0.7	0.5	0.3
Eye problems/disorders: Cataract	0.3	0.3	2.4	0.8	-0.5	-0.6	-0.1	-0.9	-0.0	-0.4	0.2	-0.1	-0.4	-1.6	-0.1	0.2	-0.0	0.1	-0.7	-0.0	0.2	-1.2	0.0	-0.1	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.1	-0.2	-1.0	-0.6	-0.6	0.3	-0.6	-0.6	-0.2	-0.6	0.2	-0.5	-0.7	-0.9	-0.7	-0.4	-0.2	0.7	-0.3	-0.1	0.8	-0.6	-0.9
Osteoarthritis (self-reported)	0.3	0.4	2.4	-1.3	-1.3	0.1	0.3	-0.3	0.2	0.3	0.5	0.2	-0.1	-0.7	0.1	0.1	0.1	0.1	-1.0	-0.3	0.7	1.5	-0.3	0.2	-0.2
Smoking status: Current	0.3	0.5	2.3	-1.0	0.2	0.5	0.6	1.5	0.4	0.5	0.3	0.5	-0.0	1.2	0.6	0.3	0.3	0.2	0.3	-0.9	-1.5	0.4	-0.8	0.5	0.6
Average weekly champagne plus white wine intake	0.3	0.4	2.6	-1.0	0.2	0.4	0.2	1.3	-0.3	0.3	-0.2	-0.2	0.7	1.6	-0.1	-0.5	-0.4	0.2	0.6	0.1	0.4	0.8	-0.1	-0.2	0.3
Ever taken oral contraceptive pill	0.3	0.3	1.3	-0.3	0.9	0.3	-0.2	0.7	-0.6	0.1	0.7	-0.6	0.2	0.7	-0.7	-0.1	-0.2	-0.8	1.1	0.1	0.2	1.1	-0.2	-0.6	0.5
Hearing aid user	0.3	0.4	1.1	0.6	-0.3	-0.6	-0.3	-0.1	-0.4	-0.8	-0.8	-0.4	-0.5	-0.6	-0.3	-0.5	-0.5	-0.8	-0.4	0.5	1.0	-0.9	0.5	-0.4	-1.1
Leg fat percentage (left)	0.3	1.0	7.0	1.9	1.8	0.3	0.5	-0.9	0.5	0.5	1.1	0.3	0.1	0.3	0.2	0.9	0.7	-0.4	0.9	-1.0	1.0	2.6	-0.9	0.3	0.1
Age started oral contraceptive pill	0.3	0.4	1.8	-1.3	-0.9	0.1	-0.6	1.1	-0.4	-0.2	-0.3	-0.4	0.8	-0.9	-0.6	-0.1	-0.1	-0.2	-0.9	0.3	1.0	-0.7	0.2	-0.4	0.2
Pack years of smoking	0.3	0.5	2.8	-0.7	-0.6	-0.1	0.1	-0.7	0.4	0.6	0.1	0.4	-0.1	-1.4	0.3	0.3	0.2	-0.3	-0.9	-0.4	-1.4	1.7	-0.4	0.4	0.3
Depression (Nagel 2018)	0.2	0.3	1.1	0.9	0.6	0.1	-0.0	1.0	-0.1	-0.2	-0.2	-0.0	1.1	0.3	0.1	-0.5	-0.5	0.2	0.1	0.9	1.0	0.7	0.2	-0.0	-0.7
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.6	0.5	-0.1	0.6	1.1	0.3	1.2	0.3	-0.6	1.2	0.1	-0.2	1.5	0.8	1.0	0.7	-1.2	-0.4	0.3	-1.6	-0.2	1.2	0.8
Schizophrenia vs Biploar Disorder	0.2	0.3	0.8	0.9	0.0	-0.8	-0.6	0.0	0.0	-0.6	-0.8	0.0	-0.6	0.0	-0.5	0.0	-0.9	-0.9	-0.1	0.7	0.1	-0.9	0.6	0.0	-0.2
Alzheimer’s Disease (in father)	0.2	0.2	0.8	0.1	0.3	0.6	-0.2	0.4	0.2	0.2	0.6	0.1	0.5	0.5	-0.2	0.4	0.6	0.4	0.3	-0.7	-0.9	0.3	-0.5	0.1	0.2
Lupus	0.2	0.3	1.7	-0.5	-0.6	-0.1	0.1	-1.1	0.1	0.2	0.3	0.0	-0.7	-1.3	0.2	0.2	0.2	0.1	-0.7	-0.3	-0.9	0.0	-0.3	0.0	0.7
Smoking Status	0.2	0.6	4.0	0.6	0.0	-0.6	0.1	0.9	-0.2	-0.8	-1.3	-0.2	-0.4	0.3	-0.0	-0.6	-0.4	-0.7	-1.0	0.3	2.0	-0.9	0.4	-0.2	-1.1
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.4	-1.2	-0.5	0.4	-0.2	0.7	-0.3	0.0	0.8	-0.4	-0.2	0.0	-0.5	0.3	0.4	0.0	-0.1	-0.5	0.6	0.3	-0.5	-0.4	0.4
Townsend deprivation index at recruitment	0.2	0.2	1.0	0.0	-0.2	0.1	-0.8	1.0	-0.4	-0.4	0.2	-0.7	0.1	-0.2	-0.5	0.2	0.5	-0.4	-0.6	-0.4	-0.8	0.1	-0.1	-0.7	0.3
Maternal smoking around birth	0.2	0.3	1.9	0.4	-0.3	-0.6	-0.4	-0.9	-0.1	0.2	0.2	-0.1	-1.4	-0.2	-0.2	0.2	-0.2	-0.8	-0.5	-0.3	0.5	1.1	-0.5	-0.1	0.5
Sitting height	0.2	1.3	5.9	-2.1	-2.4	-0.2	0.2	0.7	-0.3	-0.3	-1.1	-0.2	0.1	-2.3	0.2	-0.4	-0.2	0.6	-2.0	0.4	0.4	-2.2	0.8	-0.2	0.2
Waist circumference	0.2	0.9	4.8	1.8	0.4	-1.1	-0.6	-2.2	-0.5	-0.4	0.1	-0.6	-0.8	-1.2	-0.4	-0.2	-0.3	-0.9	-0.7	0.1	1.4	1.5	0.2	-0.6	-0.3
Nervous feelings	0.2	0.4	2.5	1.2	0.9	0.3	0.1	-0.2	-0.0	-0.4	0.1	-0.1	0.1	-0.2	-0.1	0.1	0.2	-0.5	1.2	-0.1	1.6	-1.1	0.1	-0.1	-0.1
Had menopause	0.2	0.2	1.6	0.7	0.2	-0.1	0.4	-0.6	0.3	-0.1	-0.2	0.2	-0.2	-0.5	0.3	0.3	0.2	0.3	0.1	-0.2	1.3	-0.7	-0.0	0.2	-0.1
Financial difficulties in last 2 years	0.2	0.3	1.0	0.2	-0.4	-0.7	-0.4	-0.5	-0.4	-0.4	-0.3	-0.4	-0.5	-0.4	-0.3	-0.5	-0.4	-0.6	-0.9	0.6	1.0	0.4	0.4	-0.4	-0.5
Arm fat percentage (right)	0.2	0.8	4.5	2.1	1.3	0.4	0.8	-1.5	0.6	0.4	0.9	0.4	0.1	-0.3	0.6	0.9	0.8	-0.1	0.4	-1.0	0.3	1.6	-0.8	0.4	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	1.1	-0.2	-0.8	-0.2	-0.1	0.3	0.1	-0.3	-0.7	0.1	0.1	-0.8	0.4	-0.2	-0.0	0.1	-1.0	0.7	0.0	-0.9	0.4	0.1	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.4	1.1	-0.3	-0.4	-0.7	-0.2	-0.5	-0.6	0.3	-0.6	-0.3	-1.2	-0.5	-0.3	-0.1	-0.6	-0.0	0.1	0.9	-0.8	0.2	-0.6	0.1
Hair/balding pattern: Pattern 4	0.2	0.5	2.5	-1.6	-0.7	0.4	0.5	-0.4	0.5	0.6	0.3	0.5	-0.5	-1.5	0.5	0.7	0.5	0.3	-0.4	-0.7	-0.8	0.0	-0.6	0.5	0.7
Pulse wave reflection index	0.2	0.3	1.8	-0.1	-1.0	-0.1	-0.6	-0.4	-0.5	-0.0	0.2	-0.4	0.4	-1.3	-0.6	-0.2	-0.3	-0.1	-1.3	0.5	0.2	-0.1	0.1	-0.4	0.2
Headache pain in last month	0.2	0.4	2.1	1.2	1.0	0.5	0.4	-0.2	0.6	0.3	0.1	0.6	-0.4	0.9	0.5	0.6	0.6	0.2	1.5	-0.5	0.5	-0.7	-0.2	0.6	0.3
Whole body fat mass	0.2	0.9	4.6	2.1	0.8	0.4	0.9	-1.3	0.8	0.6	1.0	0.6	-0.1	-0.4	0.8	1.1	1.1	0.3	0.3	-1.2	0.6	1.7	-0.9	0.6	0.4
Ever had bowel cancer screening	0.2	0.3	1.4	0.2	-0.8	-0.2	-0.1	0.8	0.1	-0.3	-1.2	0.1	-1.0	0.3	0.0	-0.1	-0.0	-0.4	-0.3	0.2	1.1	-0.6	0.5	0.1	-0.2
Mother’s age at death	0.2	0.3	1.5	-1.0	-1.2	-0.7	0.0	0.2	-0.3	-0.2	-0.5	-0.2	-0.6	-0.9	-0.1	-0.2	-0.2	0.5	-0.7	0.4	0.0	-1.0	0.4	-0.2	0.0
Average weekly beer plus cider intake	0.2	0.3	1.9	-0.2	-1.1	-0.2	0.1	0.6	0.3	-0.3	-0.3	0.2	-0.2	-0.6	0.1	0.1	0.3	0.7	-1.4	-0.1	-0.7	-0.4	0.1	0.2	-1.0
Commuting to job workplace: Cycle	0.2	0.3	2.7	-0.3	0.0	0.5	-0.0	1.6	-0.1	0.0	-0.6	-0.0	1.1	-0.1	-0.1	-0.4	-0.3	0.0	-0.2	0.4	0.3	0.6	0.5	-0.0	-0.6
Bipolar Disorder or Schizophrenia	0.1	0.2	0.7	-0.2	0.5	0.2	0.6	0.4	0.1	-0.1	-0.6	0.1	0.8	-0.4	0.6	0.1	-0.0	0.3	-0.1	0.5	0.8	-0.2	0.5	0.1	-0.2
Coronary Artery Disease (CAD)	0.1	0.1	1.1	0.0	0.0	0.1	0.0	0.5	0.0	0.2	0.5	0.0	0.0	0.0	0.0	0.0	-0.3	0.0	0.9	0.2	-1.0	0.0	-0.2	0.0	0.0
Neuroticism (2016)	0.1	0.2	1.7	0.2	0.9	0.1	0.1	-0.1	-0.1	0.1	0.4	-0.1	0.3	-0.1	-0.3	0.1	0.0	-0.7	0.3	-0.3	1.3	0.2	-0.3	-0.1	0.4
Blood Red Count	0.1	1.4	6.1	1.8	-1.3	-1.4	-1.2	0.1	-0.8	-0.8	-0.2	-0.8	-2.5	0.2	-0.5	-0.8	-1.1	-1.2	0.9	1.4	1.9	1.5	1.1	-0.8	-1.0
Medication: Co-codamol	0.1	0.1	0.8	0.2	0.9	0.5	0.3	0.2	0.1	0.0	-0.1	0.1	0.5	0.6	0.2	0.2	0.3	-0.7	0.3	-0.2	-0.0	0.5	-0.1	0.1	-0.0
Trunk fat percentage	0.1	0.5	4.1	2.0	1.1	-0.4	0.5	-1.3	-0.1	-0.5	-0.2	-0.3	-0.0	-0.3	0.1	0.0	-0.1	-0.5	0.6	0.0	1.4	0.7	0.3	-0.3	-0.7
Trunk fat mass	0.1	0.6	4.8	2.2	0.8	0.1	0.9	-1.4	0.5	0.2	0.5	0.3	-0.1	-0.6	0.7	0.7	0.6	0.2	0.2	-0.7	1.0	1.2	-0.4	0.3	0.1
Body fat percentage	0.1	0.6	4.3	2.1	1.3	-0.1	0.5	-1.3	0.1	-0.1	0.3	-0.1	-0.0	-0.1	0.2	0.4	0.3	-0.4	0.6	-0.5	1.2	1.4	-0.2	-0.1	-0.5
Qualifications: College or University degree	0.1	0.3	2.5	-0.3	-0.7	0.6	0.7	0.9	0.4	0.1	-0.3	0.5	0.5	0.3	0.6	0.2	0.4	0.9	0.0	-0.0	-0.3	-1.6	0.2	0.5	0.2
Medication for pain relief, constipation, heartburn	0.1	0.2	0.9	-1.0	-0.4	-0.0	0.4	0.0	0.5	0.5	-0.4	0.6	-0.4	0.1	0.9	0.1	-0.0	0.9	0.2	0.2	-0.4	-0.1	0.0	0.6	0.5
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.1	0.7	0.3	-0.0	0.1	0.3	0.2	-0.1	-0.3	0.1	-0.1	0.8	-0.7	0.2	0.1	-0.1	0.2	-0.1	0.3	0.4	-0.5	0.3	-0.1	-0.0
Tanning	0.0	0.6	1.3	-0.7	1.1	-0.8	-0.9	0.0	-0.8	-0.5	-0.9	-0.8	-0.6	0.6	-1.0	-0.9	-0.8	-1.1	1.0	0.6	0.7	0.2	0.6	-0.8	-0.4
Father’s age at death	0.0	0.1	0.3	-0.6	0.0	0.0	0.3	0.4	0.1	0.0	0.5	0.1	0.4	-0.1	-0.1	0.0	0.0	0.3	0.1	-0.0	0.1	0.3	-0.2	0.1	-0.0

Hub : Genes

OPRL1

Models

Trait associations