Best TWAS P=2.28e-10 · Best GWAS P=7.61e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | RP11-665G4.1 | 0.13 | -0.01 | lasso | 6 | 0.00 | 3.9e-01 | -4.9 | -5.8 | 7.7e-09 | 0.77 | 0.03 | 0.87 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | RP11-665G4.1 | 0.21 | 0.00 | lasso | 6 | 0.03 | 1.5e-02 | -6.4 | -5.7 | 1.1e-08 | 0.71 | 0.03 | 0.82 | FALSE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | RP11-665G4.1 | 0.19 | 0.01 | lasso | 4 | 0.02 | 8.8e-02 | -5.1 | -5.8 | 5.4e-09 | 0.81 | 0.03 | 0.93 | FALSE |
| 4 | GTEx | Esophagus Muscularis | CC2D2A | 0.14 | 0.00 | lasso | 4 | 0.00 | 5.5e-01 | 4.1 | -6.1 | 1.2e-09 | 0.78 | 0.02 | 0.86 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | C1QTNF7 | 0.10 | 0.07 | lasso | 3 | 0.03 | 1.6e-03 | -6.5 | -6.3 | 2.3e-10 | 0.99 | 0.00 | 0.99 | TRUE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | C1QTNF7 | 0.04 | 0.04 | blup | 98 | 0.04 | 1.6e-05 | -4.9 | -5.6 | 2.4e-08 | 0.71 | 0.16 | 0.72 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Adenocarcinoma | C1QTNF7 | 0.04 | 0.03 | lasso | 3 | 0.01 | 1.5e-02 | 4.8 | -5.3 | 1.0e-07 | 0.68 | 0.04 | 0.41 | FALSE |