[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr4:25,052,785-27,725,689

Best TWAS P=8.97e-14 · Best GWAS P=1.33e-21 conditioned to 0.0626

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RBPJ 0.06 0.01 blup 397 0.03 9.9e-05 9.4 7.1 1.3e-12 0.77 0.01 0.99 FALSE
2 GTEx Esophagus Mucosa SMIM20 0.33 0.32 enet 5 0.33 2.0e-22 -5.2 5.3 1.2e-07 0.04 1.00 0.00 FALSE
3 GTEx Nerve Tibial SEL1L3 0.27 0.18 enet 35 0.20 8.1e-14 -4.9 6.4 1.4e-10 0.04 1.00 0.00 TRUE
4 METSIM Adipose SEL1L3 0.08 0.03 bslmm 520 0.04 1.5e-06 -5.1 6.1 1.3e-09 0.06 0.85 0.00 FALSE
5 METSIM Adipose STIM2 0.05 0.01 blup 431 0.01 1.1e-02 -3.3 7.1 1.3e-12 0.42 0.18 0.38 TRUE
6 ROSMAP Brain Pre-frontal Cortex RBPJ 0.10 0.02 bslmm 469 0.05 5.3e-07 9.0 7.5 9.0e-14 0.60 0.04 0.95 TRUE
7 The Cancer Genome Atlas Breast Invasive Carcinoma CCKAR 0.03 0.00 blup 63 0.01 4.8e-03 7.4 -5.1 3.0e-07 -0.61 0.01 0.07 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma C4orf52 0.11 0.08 lasso 4 0.05 5.8e-04 -5.1 5.3 1.2e-07 0.03 0.00 0.98 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C4orf52 0.12 0.12 enet 5 0.14 1.1e-15 -5.1 5.4 6.0e-08 0.04 0.00 1.00 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma RBPJ 0.08 0.00 blup 70 0.00 1.4e-01 9.4 6.9 5.3e-12 0.62 0.01 0.44 TRUE
11 The Cancer Genome Atlas Prostate Adenocarcinoma C4orf52 0.31 0.30 lasso 4 0.32 3.1e-34 -5.1 5.3 1.4e-07 0.05 0.01 0.99 FALSE