Hub : Genes

C1QTNF7

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1440	0.0290	4.1e-14	0.110	0.124	0.180	0.160	0.180	2.7e-13	6.5e-15	2.3e-21	4.7e-19	2.1e-21
2	GTEx	Artery Aorta	0.2890	0.0720	1.3e-05	0.109	NA	0.048	NA	0.068	1.3e-06	NA	1.1e-03	NA	1.3e-04
3	GTEx	Skin Sun Exposed Lower leg	0.1010	0.0340	6.5e-04	0.066	NA	0.015	NA	0.030	3.5e-06	NA	1.8e-02	NA	1.6e-03
4	METSIM	Adipose	0.1037	0.0273	2.6e-09	0.054	0.075	0.070	0.072	0.068	1.4e-08	2.7e-11	1.3e-10	6.3e-11	2.3e-10
5	NTR	Blood	0.1291	0.0211	0.0e+00	0.135	0.149	0.163	0.157	0.160	3.7e-41	8.7e-46	2.5e-50	2.7e-48	2.8e-49
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0396	0.0198	3.7e-04	0.041	0.042	0.023	NA	0.033	2.0e-05	1.6e-05	1.0e-03	NA	1.2e-04
7	TCGA	Lung Adenocarcinoma	0.0394	0.0203	4.1e-03	0.026	0.010	0.006	NA	0.011	4.4e-04	2.3e-02	5.1e-02	NA	1.5e-02
8	TCGA	Pancreatic Adenocarcinoma	0.1380	0.0670	4.7e-03	0.005	-0.005	0.004	NA	0.007	1.8e-01	5.7e-01	2.2e-01	NA	1.6e-01
9	TCGA	Prostate Adenocarcinoma	0.1032	0.0394	4.6e-05	0.012	0.038	0.025	NA	0.024	1.8e-02	6.3e-05	1.0e-03	NA	1.4e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.1	0.2	0.9	0.2	0.9	-0.4	-0.2	-0.1	0.8	0.0	-0.5	0.2
Bipolar Disorder or Schizophrenia	0.4	1.1	4.7	0.1	2.2	-1.1	-0.0	-0.4	-0.2	-0.9	-0.3	1.6
Depressed Affect (Nagel 2018)	3.7	7.7	15.7	-4.0	-0.7	-3.0	-3.3	-3.5	-2.6	-3.0	0.7	-2.3
Depression (Nagel 2018)	4.6	6.9	11.3	-3.3	-0.9	-2.5	-3.4	-2.9	-3.2	-2.5	2.6	-1.3
Intelligence (Savage-Jansen 2018)	1.3	4.1	9.2	1.3	-1.8	3.0	2.0	1.2	2.9	2.8	0.7	0.3
Neuroticism (Nagel 2018)	4.9	11.6	23.7	-4.9	-1.9	-3.2	-4.0	-4.2	-3.3	-3.5	0.9	-3.0
Schizophrenia (2018)	0.6	1.2	4.0	-0.0	2.0	-1.2	0.2	-0.4	-0.9	-1.2	0.1	1.8
Schizophrenia vs Biploar Disorder	0.2	0.3	1.0	-0.2	-1.0	0.0	-0.6	-0.3	-0.6	-0.7	0.2	-0.2
Worry (Nagel 2018)	1.6	3.3	5.7	-2.1	-1.3	-1.6	-2.3	-1.6	-1.9	-2.4	1.6	-1.3
Alzheimer’s Disease (in mother)	2.2	2.5	7.3	-1.1	2.5	-0.7	-1.0	-1.3	-1.5	-1.4	2.7	0.9
Alzheimer’s Disease (in father)	1.1	1.2	3.9	0.7	0.3	0.6	1.3	0.0	1.4	2.0	-1.2	-1.1
Alzheimer’s Disease (including proxy)	1.1	1.6	7.5	-0.8	2.7	-1.1	-0.1	-1.1	-1.3	-0.9	1.3	0.2
Crohns Disease (2017)	1.2	2.7	9.4	-3.0	-1.0	-0.2	-1.5	-3.1	-1.3	0.3	0.9	-0.6
Irritable Bowel Disease (IBD)	0.6	1.5	3.6	-1.5	-1.5	0.7	-0.3	-1.9	0.6	1.8	-0.5	-0.8
Ulcerative Colitis (UC)	1.1	2.0	5.0	1.3	-0.7	1.2	1.4	0.8	2.2	2.2	-1.3	-0.2
Major Depression (MDD)	5.4	6.6	14.8	-2.3	-0.8	-3.1	-2.3	-2.9	-2.7	-3.9	0.1	-2.8
Reaction Time	1.6	3.0	11.7	-0.3	1.2	-3.1	-1.4	-0.1	-3.4	-1.2	0.3	-0.9
Verbal and Numeric Reasoning (VNR)	1.5	3.6	10.0	0.2	-2.7	3.2	0.4	0.1	2.3	2.8	0.9	0.6
Breast Cancer	0.7	1.6	3.5	1.9	0.7	1.3	1.3	1.8	0.6	1.2	0.8	1.1
Ovarian Cancer	0.7	1.0	3.2	1.3	-0.7	-0.3	0.9	1.5	0.6	-0.2	-1.8	-0.1
Prostate Cancer	1.1	1.5	4.6	2.2	0.2	-0.5	1.2	2.0	-0.2	0.9	0.3	-1.5
Age at First Birth	2.7	3.9	9.4	0.7	-3.1	2.7	1.6	0.6	2.8	2.3	-1.1	-0.8
Bipolar Disorder (2011)	0.5	0.5	2.3	0.5	1.0	0.1	-0.0	0.3	0.3	0.3	0.4	1.5
Body Mass Index (BMI) (2010)	0.7	1.0	2.3	1.5	1.3	0.6	1.3	1.2	0.5	-0.2	0.0	1.0
Coronary Artery Disease (CAD)	1.5	1.8	4.5	-1.1	-0.0	-2.1	-1.3	-1.0	-2.1	-1.4	-0.3	-1.1
Crohns Disease (2012)	0.6	0.9	2.2	-1.1	0.7	-1.0	-0.8	-0.8	-1.5	-0.6	1.2	0.4
Mean Putamen Volume	0.8	1.0	3.3	-1.7	0.5	0.3	-1.1	-1.8	0.2	1.0	0.3	-0.1
Fasting Glucose	0.3	0.3	1.5	-0.7	-1.2	-0.1	0.2	-0.6	0.2	-0.2	-0.7	-0.4
HbA1C	0.9	1.0	4.2	-2.0	-0.3	-0.5	-0.6	-1.8	-0.2	-0.2	-0.9	-0.3
HDL Cholesterol	0.5	0.9	3.1	-0.4	0.3	-0.3	1.6	-0.5	0.9	0.8	-1.7	0.7
LDL Cholesterol	0.3	0.4	1.7	0.7	1.3	-0.5	0.2	0.4	0.4	-0.4	-0.8	0.3
Lupus	0.5	0.7	2.3	0.3	1.0	0.3	1.3	-0.2	-0.1	1.5	-1.1	0.2
Neuroticism (2016)	2.3	3.3	12.2	-3.2	-1.1	-0.4	-1.7	-3.5	-0.9	-0.7	1.0	-0.9
Primary Biliary Cirrhosis	2.3	3.3	6.5	0.8	-0.7	-1.8	-2.0	0.6	-2.3	-2.5	2.5	-1.7
Rheumatoid Arthritis	0.1	0.2	0.6	-0.0	-0.2	-0.2	0.1	-0.6	0.0	0.7	-0.8	0.0
Schizophrenia (2014)	0.4	0.8	2.1	-0.2	1.3	-0.7	-0.1	-0.8	-0.7	-1.3	0.1	1.5
Triglycerides	0.4	0.7	4.6	-0.2	2.1	0.3	0.8	-0.2	-0.1	0.3	-0.3	0.6
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.4	1.3	-0.3	1.2	-0.1	1.5	0.8	1.4	-0.1	-0.2
Ulcerative Colitis	1.1	1.6	4.4	0.0	-2.1	1.4	-0.2	0.1	1.8	1.8	-0.9	-0.5
Blood Eosinophil Count	0.2	1.3	4.5	-2.1	-0.8	-0.3	-1.2	-1.2	-0.0	-0.9	1.1	-1.0
Blood Platelet Count	0.0	0.4	1.6	-0.1	-0.0	-1.2	0.4	-0.2	-0.7	-0.8	0.4	-0.9
Blood Red Count	2.4	23.6	85.9	-8.4	-2.9	-1.9	-3.5	-9.3	-2.3	-2.8	-2.1	-3.7
Blood White Count	0.8	5.8	19.3	-1.7	-1.2	-2.6	-2.1	-2.1	-2.7	-4.4	0.7	-2.2
Heel T-Score	0.2	1.5	5.6	-0.1	1.5	0.9	0.9	-0.2	1.8	2.4	-0.1	0.8
BMI	0.2	0.9	1.9	1.0	1.1	-1.2	0.8	0.5	-0.1	-1.4	1.2	0.6
Height	0.3	5.5	21.6	-4.1	-1.8	0.5	0.6	-4.7	1.9	0.6	-1.8	-0.6
Waist Hip Ratio (WHR)	3.5	15.7	40.2	-1.9	-1.4	-6.3	-3.3	-2.1	-5.6	-5.3	-0.9	-4.5
Systolic Blood Pressure	0.5	2.3	9.1	0.0	0.5	-3.0	-0.6	0.9	-2.0	-2.3	-0.1	-0.8
Smoking Status	1.9	4.5	7.5	-2.6	0.2	-2.3	-2.0	-2.3	-2.6	-2.7	0.7	-2.0
Allergy or Eczema	0.3	0.9	1.9	1.2	0.2	0.7	1.0	1.4	0.8	0.9	0.8	1.2
Cardiovascular Disease	0.4	1.5	3.5	0.2	-1.9	-1.8	-0.4	0.3	-1.4	-1.8	-0.4	-1.0
Hypothyroidism (self reported)	0.5	1.2	4.0	0.9	-0.5	0.2	1.8	0.4	1.3	-0.2	-2.0	0.7
Respiratory disease	0.3	0.7	2.2	-1.3	0.7	-0.3	-0.2	-1.1	-0.6	0.1	1.5	-0.0
Type 2 Diabetes (T2D) (2018)	1.3	2.4	6.5	-1.5	-0.4	-2.1	-2.2	-1.3	-2.5	-1.4	-0.1	-0.0
Lung FEV1/FVC ratio	1.3	6.4	18.6	3.9	3.5	-0.4	2.2	4.3	1.1	0.6	-0.3	2.2
Lung FVC	0.8	4.3	12.9	1.9	-0.4	3.6	1.2	2.1	3.0	2.0	0.4	1.6
Neuroticism	3.6	8.7	16.1	-4.0	-1.6	-3.0	-3.3	-3.2	-2.6	-3.4	0.7	-3.2
Chronotype (morning person)	0.4	0.8	2.5	1.6	0.3	-0.2	-0.3	0.8	-1.6	-0.2	1.0	-0.8
Hair Pigment	0.0	0.2	0.6	0.1	0.4	-0.8	0.0	0.0	-0.3	0.2	0.1	-0.7
Tanning	0.1	1.3	2.9	-0.6	-1.4	-1.3	-0.7	-0.9	-1.3	-1.7	-0.2	-1.3
Hand grip strength (left)	0.2	0.5	1.6	-0.7	-0.2	1.0	-0.1	-0.8	0.6	-0.1	1.2	0.8
Number of treatments/medications taken	1.0	1.8	5.9	-2.0	-0.7	-1.0	-1.2	-2.4	-1.2	-1.1	0.3	-0.7
Average weekly spirits intake	0.8	1.0	2.5	-1.0	-1.0	-0.7	-0.7	-1.6	-1.0	-0.9	-0.2	-1.3
Sensitivity / hurt feelings	1.3	2.2	9.3	-3.0	-0.5	-1.1	-1.2	-2.2	-0.8	-1.3	-0.7	-0.3
Frequency of depressed mood in last 2 weeks	4.6	6.4	13.3	-3.4	-1.1	-2.6	-3.6	-2.6	-3.0	-2.6	1.3	-0.8
Hearing difficulty/problems: Yes	0.3	0.5	1.2	0.5	1.1	-0.5	0.5	0.8	-0.7	0.8	0.2	-0.7
Relative age of first facial hair	0.5	1.1	3.1	-0.6	0.3	1.6	-0.1	-0.3	0.2	1.1	1.5	1.8
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.4	-0.8	-0.4	-1.1	-0.7	-0.9	-1.4	-1.6	-0.2	-0.5
Ever used hormone-replacement therapy (HRT)	0.4	0.6	2.0	-0.6	1.1	-0.3	1.4	-0.7	0.8	-0.1	-0.6	-0.0
Ever had hysterectomy (womb removed)	0.4	0.5	1.9	0.7	0.2	-0.5	1.4	0.3	-0.2	-0.7	-0.9	-0.4
Systolic blood pressure, automated reading	0.1	0.4	1.5	0.0	-0.3	-1.2	0.0	0.4	-0.9	-0.7	0.5	-0.4
Eye problems/disorders: Diabetes related eye disease	1.0	1.2	2.8	-0.5	-1.7	-0.9	-1.0	-0.2	-0.8	0.4	-1.4	-1.6
Angina	0.8	1.1	5.6	-0.1	0.6	-0.0	0.8	-0.3	0.3	2.4	-0.9	-1.4
Medication for hormone replacement therapy	1.0	1.1	2.8	-1.5	-0.1	1.5	-0.0	-1.7	1.0	0.5	-0.5	1.2
Vitamin and mineral supplements	0.2	0.3	0.7	0.5	0.1	0.7	0.2	0.4	0.9	-0.7	0.1	0.6
Supplements: Zinc	0.7	0.7	1.6	-0.2	-1.2	-0.9	-0.4	-0.7	-1.2	-0.4	1.2	-0.7
Medication: Co-codamol	0.4	0.5	1.2	0.3	0.6	-1.0	1.1	-0.3	-0.3	-0.7	-1.1	0.2
Medication: Metformin	2.2	3.1	7.2	-1.6	-1.1	-2.7	-2.0	-1.2	-2.2	-2.0	-0.6	-1.6
Diabetes (father)	0.2	0.2	0.7	-0.6	-0.0	-0.1	-0.9	-0.4	0.1	0.0	0.8	0.0
Diabetes (mother)	0.1	0.2	0.8	-0.4	0.9	-0.2	-0.3	0.2	-0.3	-0.4	0.5	0.1
Severe depression (siblings)	0.2	0.2	1.1	-0.5	0.2	-0.2	0.2	-0.6	0.1	-0.2	-0.2	1.1
Pack years adult smoking proportion	2.7	4.1	8.7	-2.1	-2.3	-1.3	-2.0	-2.6	-1.8	-2.9	-0.7	-1.5
Impedance of leg (right)	0.6	2.8	7.9	-1.5	0.4	-2.3	-1.7	-0.6	-2.8	-1.7	-0.9	-1.5
Leg fat-free mass (left)	0.1	0.4	1.5	0.0	-0.8	0.6	0.7	-0.8	1.2	0.0	0.2	0.2
Trunk fat percentage	0.5	2.1	6.6	-1.5	0.2	-2.6	0.4	-2.0	-1.0	-1.9	-0.6	-1.2
Hand grip strength (right)	0.5	1.5	4.0	-1.2	-1.4	2.0	-0.3	-1.1	1.3	1.1	0.9	1.0
Townsend deprivation index at recruitment	1.0	1.4	3.8	-0.2	0.7	-1.9	-0.1	-0.6	-1.0	-1.1	-1.4	-2.0
Current tobacco smoking	2.1	3.4	7.8	-2.0	0.3	-2.8	-1.0	-1.7	-2.2	-2.2	-1.0	-2.1
Average weekly fortified wine intake	0.6	0.7	2.4	0.6	0.2	-0.3	-1.2	0.8	-1.0	-0.4	1.6	0.2
Maternal smoking around birth	1.6	2.3	6.0	-1.2	0.7	-2.2	-1.0	-1.0	-2.3	-2.4	0.1	-0.8
Fed-up feelings	2.5	4.6	8.2	-2.8	0.8	-2.8	-1.9	-2.5	-2.3	-2.9	-0.6	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	4.4	5.9	10.4	-3.2	-0.2	-2.8	-2.4	-2.9	-3.1	-2.9	1.5	-0.9
Relative age voice broke	0.7	1.1	4.6	1.1	0.1	0.9	0.4	1.2	0.2	-0.1	1.2	2.1
Taking other prescription medications	1.0	1.6	5.3	-2.3	0.5	-1.1	-0.8	-2.1	-1.0	-0.8	0.8	-0.2
Age when periods started (menarche)	0.4	1.0	5.0	0.4	-0.8	-0.8	-0.6	1.3	-0.2	-2.2	0.3	0.3
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.8	-0.3	-0.5	0.3	0.6	-0.9	0.4	0.0	-0.6	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	3.0	-0.5	1.7	-0.0	1.3	-0.5	0.3	0.6	-0.7	0.9
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.9	0.4	-0.9	-0.4	1.0	0.6	0.8	-0.3	-0.9	-0.9
Qualifications: CSEs or equivalent	1.0	1.4	4.7	-1.9	-1.1	0.0	-1.0	-2.2	-0.9	-0.6	-0.2	-0.6
Serious illness, injury or assault to yourself	1.1	1.3	2.7	-1.4	0.3	-0.9	-0.7	-1.6	-1.6	-1.6	-0.3	-0.6
High blood pressure	0.6	1.7	4.9	-0.1	-0.8	-2.2	-0.8	-0.2	-1.9	-2.2	-0.0	-1.0
Hayfever, allergic rhinitis or eczema	0.6	1.4	3.3	0.8	0.8	0.3	1.1	1.1	1.6	0.9	-1.5	1.8
Multivitamins +/- minerals	0.3	0.4	1.1	-0.7	0.4	-1.0	-0.4	-0.4	-0.9	-0.1	0.5	0.1
Stomach or abdominal pain in last month	0.3	0.4	2.3	0.4	0.6	0.5	-0.1	-0.2	-0.2	-0.1	0.3	1.5
Supplements: Glucosamine	1.3	1.7	4.0	1.6	1.1	-0.4	2.0	1.7	0.9	1.2	-1.5	-0.1
Diverticular disease/diverticulitis (self-reported)	5.1	6.0	18.1	2.4	0.8	3.1	2.3	1.6	2.8	2.2	0.3	4.3
Medication: Atenolol	0.5	0.6	2.3	-0.3	0.9	-1.2	-0.3	-0.1	-1.5	-0.9	-0.4	-0.1
Medication: Levothyroxine sodium	1.1	1.8	4.6	1.5	-0.3	1.0	2.1	0.9	2.1	0.5	-1.4	1.1
Sitting height	0.7	4.8	17.1	-4.0	-1.6	-0.7	-1.3	-4.1	-0.7	-1.0	-1.4	-1.5
Chronic bronchitis/emphysema (father)	1.4	1.7	4.4	-1.8	0.0	-1.4	-1.0	-1.7	-2.1	-0.6	-0.7	-0.8
High blood pressure (mother)	0.4	0.6	3.0	-0.3	1.1	0.5	-1.7	0.3	-0.5	0.3	0.4	0.5
Body mass index (BMI)	0.1	0.3	0.9	-0.1	0.5	-0.9	0.4	-0.9	-0.1	-0.6	0.6	-0.2
Impedance of leg (left)	0.6	2.7	6.6	-2.0	0.5	-2.2	-1.6	-0.9	-2.6	-1.5	-1.0	-1.4
Leg predicted mass (left)	0.1	0.4	1.6	0.1	-0.8	0.7	0.8	-0.7	1.3	-0.0	0.3	0.3
Trunk fat mass	0.4	1.9	4.9	-1.6	-0.1	-2.2	0.2	-2.1	-0.8	-1.7	-0.2	-1.2
Waist circumference	0.3	1.1	4.5	-0.5	-0.1	-2.1	-0.2	-1.1	-1.0	-1.5	0.2	-0.7
Number of incorrect matches in round	0.3	0.5	1.9	0.4	0.3	-0.5	-0.6	0.5	-0.2	-1.2	1.4	-0.2
Past tobacco smoking	2.1	3.9	8.6	2.0	-0.5	1.4	2.9	1.4	2.8	1.9	-2.6	0.5
Alcohol usually taken with meals	1.0	1.6	4.3	-1.4	0.7	1.7	-0.9	-0.9	0.4	2.1	1.3	1.1
Nervous feelings	0.2	0.4	2.2	-0.9	-0.1	0.7	-0.2	-0.4	-0.1	0.2	1.5	0.5
Frequency of tenseness / restlessness in last 2 weeks	2.9	4.5	9.7	-2.1	1.6	-2.7	-2.2	-1.4	-2.9	-3.1	1.3	-0.6
Hearing difficulty/problems with background noise	0.6	0.9	3.2	-1.8	0.8	-0.6	-0.2	-1.7	-0.7	0.2	-0.8	-0.0
Hair/balding pattern: Pattern 2	0.6	0.8	2.7	0.2	-0.5	0.9	0.6	-0.6	1.6	1.3	-0.6	-0.4
Had menopause	1.0	1.3	4.0	0.5	-0.7	1.4	1.3	-0.1	2.0	1.3	-1.0	0.5
Had other major operations	0.9	1.1	2.3	-1.3	-0.4	-0.7	-0.8	-1.5	-1.2	-0.9	-0.8	-1.3
Forced vital capacity (FVC)	0.5	1.7	5.6	1.1	-1.5	2.4	0.1	1.0	1.9	0.6	0.3	1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.9	-1.0	1.0	0.4	0.1	-0.9	0.1	0.5	0.0	0.3
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	2.2	-0.9	1.1	-0.8	0.9	-0.6	0.9	0.9	-1.5	0.1
Qualifications: None of the above	3.1	6.6	16.0	-1.9	0.1	-3.3	-2.6	-1.4	-4.0	-3.8	1.4	-1.9
Financial difficulties in last 2 years	1.9	2.5	5.2	-1.4	1.4	-2.2	-2.1	-1.0	-2.3	-1.6	-0.4	-0.7
Mouth/teeth dental problems	0.4	0.6	1.5	1.2	1.0	0.4	0.4	1.1	0.2	0.3	1.1	0.6
Heart attack	0.7	0.8	2.9	-1.1	1.7	-0.1	-0.1	-1.0	-0.1	0.2	-1.4	-0.8
Allergy	0.2	0.4	1.6	-0.1	-0.7	0.0	-0.7	-0.1	-0.7	-0.5	0.8	-1.2
Pain all over the body in last month	0.9	0.9	2.7	-0.4	0.1	-1.6	0.1	0.2	-0.6	-1.6	-0.8	-1.4
Diabetes (self-reported)	1.5	2.4	5.8	-1.4	-1.4	-1.6	-2.2	-1.4	-2.4	-1.1	-0.3	-1.0
Hayfever/allergic rhinitis (self-reported)	1.6	2.2	6.5	1.2	2.0	0.6	1.7	1.2	1.5	1.0	-0.2	2.5
Medication: Ramipril	1.6	2.1	6.1	-0.6	1.8	-2.3	-0.8	-0.4	-1.6	-2.5	0.3	-0.2
Medication: Simvastatin	1.2	1.8	5.4	-0.9	0.7	-2.3	-0.6	-1.0	-1.8	-1.1	-0.9	-1.6
Fluid intelligence score	1.1	2.2	7.6	-0.1	-2.0	2.8	-0.7	0.1	1.8	2.0	0.1	0.6
Illnesses of siblings	0.7	0.9	2.1	1.4	1.1	-0.9	0.3	1.4	-0.9	0.5	0.1	-1.0
Neuroticism score	3.4	7.2	12.3	-3.5	-1.0	-3.1	-2.9	-2.8	-2.6	-3.5	0.7	-2.5
Weight	0.1	0.5	2.2	-0.9	-0.3	-0.9	0.2	-1.5	0.1	-0.8	0.3	-0.5
Impedance of arm (right)	0.1	0.7	2.3	-0.7	-0.6	-1.0	-0.3	-0.0	-1.1	-1.5	0.1	-0.7
Arm fat percentage (right)	0.2	0.6	1.9	-0.4	0.2	-1.4	0.7	-1.0	-0.3	-1.2	0.5	-0.4
Trunk fat-free mass	0.1	0.4	0.8	-0.5	-0.9	0.7	-0.0	-0.9	0.8	0.4	0.4	-0.6
Hip circumference	0.1	0.6	1.9	-0.0	0.1	0.5	1.3	-0.5	1.4	0.3	0.6	0.8
Time employed in main current job	1.2	1.4	3.8	0.1	-1.4	2.0	-0.3	-0.1	0.9	1.5	1.8	-0.4
Alcohol intake versus 10 years previously	0.6	0.9	2.5	0.4	1.4	0.8	-0.3	0.1	-1.5	-0.2	1.6	0.8
Father’s age at death	2.6	3.5	6.4	2.5	1.0	1.9	2.4	2.2	1.7	1.7	0.2	2.0
Worrier / anxious feelings	0.8	1.5	4.8	-0.9	-0.6	-1.1	-1.2	-0.4	-1.3	-2.2	1.1	-1.5
Frequency of tiredness / lethargy in last 2 weeks	2.5	4.1	10.3	-2.3	0.3	-2.5	-1.8	-2.2	-2.5	-3.2	-0.5	-0.6
Falls in the last year	0.2	0.3	1.2	-0.5	-0.3	-1.1	-0.2	-0.1	-0.6	-0.9	0.0	-0.4
Hair/balding pattern: Pattern 3	0.5	0.7	3.2	0.1	0.8	-0.3	1.0	0.5	-0.3	-0.1	-1.8	1.1
Number of live births	1.2	1.7	5.4	1.7	1.6	-0.2	2.3	1.6	1.0	0.6	0.3	0.2
Forced expiratory volume in 1-second (FEV1)	0.7	2.3	5.5	1.8	-0.8	2.4	0.2	1.8	2.0	1.0	0.5	1.6
Pulse rate	0.5	0.8	1.6	1.1	0.7	-1.2	1.3	0.4	0.5	-0.9	-1.0	0.2
Happiness	1.0	1.2	4.8	-1.1	-0.5	0.7	-1.7	-0.3	-0.0	0.9	2.2	0.7
Noisy workplace	0.7	0.8	2.1	-0.4	0.0	-1.3	-0.4	-0.6	-1.4	-0.6	-1.0	-1.3
Qualifications: A levels/AS levels or equivalent	1.9	4.2	9.9	2.4	-0.7	2.4	1.3	2.5	2.5	3.1	0.2	1.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.7	0.1	-0.9	-0.9	-1.2	-0.1	-1.3	-1.0	-0.0	-1.0
Mouth/teeth dental problems: Dentures	1.2	2.0	5.9	-1.1	0.5	-2.4	-0.3	-0.8	-2.0	-2.0	0.2	-1.3
Asthma	0.4	0.8	3.0	-1.6	-0.1	-0.5	-0.7	-1.7	-0.5	0.5	0.5	-0.3
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.2	5.9	-0.4	-0.9	-1.5	-0.6	-0.4	-0.9	-0.8	0.5	-2.4
Medication: Cholesterol lowering	0.5	0.8	1.3	-1.0	-1.0	-0.7	-0.0	-1.1	-0.8	-0.4	-1.1	-1.1
Depression (self-reported)	2.1	2.5	5.8	-2.3	-0.0	-0.5	-2.1	-2.4	-1.6	-1.3	1.3	0.5
Medication: Lansoprazole	0.3	0.4	1.0	-0.2	-0.8	0.4	-1.0	-0.7	0.2	0.6	-0.7	0.0
Prospective memory result	0.6	0.7	1.6	0.6	1.0	-1.3	1.1	0.7	-0.3	-0.6	-0.3	-1.2
Lung cancer (father)	1.0	1.1	4.8	0.6	-0.6	-1.4	-0.7	-0.1	-1.0	-0.7	0.6	-2.2
Illnesses of mother	0.9	1.2	2.6	0.1	-1.6	0.1	1.6	-0.3	1.5	-0.4	-1.4	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.2	8.2	1.7	-1.0	2.9	1.0	1.6	2.5	1.4	-0.0	2.1
Pulse wave Arterial Stiffness index	2.8	3.2	8.0	-1.1	-1.9	-2.5	-0.7	-1.0	-1.2	-2.5	-0.9	-2.8
Impedance of arm (left)	0.2	0.8	1.8	-0.7	-0.6	-1.3	-0.3	0.1	-1.1	-1.3	-0.9	-0.7
Arm fat mass (right)	0.1	0.6	1.8	-0.7	-0.1	-1.2	0.4	-1.4	-0.2	-1.0	0.4	-0.4
Trunk predicted mass	0.1	0.4	0.9	-0.5	-0.9	0.7	0.0	-0.9	0.8	0.4	0.3	-0.5
Standing height	0.1	1.3	4.2	-2.1	-1.6	-0.1	-0.3	-1.8	0.5	-0.3	-0.7	-1.0
Length of working week for main job	1.0	1.1	2.1	-1.4	0.5	-1.2	-0.9	-1.4	-1.4	-0.8	-0.7	-0.7
Exposure to tobacco smoke at home	3.0	3.4	7.5	-1.4	-0.2	-2.7	-1.6	-1.7	-2.3	-2.2	0.5	-2.3
Breastfed as a baby	1.7	2.2	8.2	2.5	0.9	0.0	0.5	2.9	0.6	1.0	-1.5	0.5
Tense / ‘highly strung’	4.2	6.9	13.7	-3.0	-0.1	-3.2	-2.7	-2.8	-3.7	-3.3	1.5	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	3.4	5.2	16.2	-4.0	-1.6	-1.6	-2.5	-3.6	-1.4	-1.2	0.6	-1.7
Hair/balding pattern: Pattern 4	0.2	0.4	1.9	0.2	0.1	0.6	0.5	0.3	-0.6	1.0	1.4	-0.1
Birth weight of first child	2.9	5.2	13.1	2.6	1.8	1.5	2.5	2.0	2.5	1.5	-1.8	3.6
Peak expiratory flow (PEF)	0.4	0.9	2.9	1.7	0.5	0.4	0.1	1.7	0.7	1.0	0.6	0.1
Pulse wave reflection index	0.7	0.9	2.2	-1.2	-1.2	0.5	-1.2	-0.9	0.2	-0.4	1.5	-0.0
Ever highly irritable/argumentative for 2 days	2.8	3.3	13.4	-3.4	-0.2	-1.5	-0.6	-3.7	-0.8	-0.7	-0.8	-1.0
Loud music exposure frequency	0.6	0.7	1.8	-1.3	-0.5	-0.2	-0.6	-1.4	-1.1	-0.4	-0.7	-0.1
Qualifications: O levels/GCSEs or equivalent	1.7	2.7	6.5	1.3	-1.4	1.2	1.8	0.7	2.5	2.5	-1.5	-0.2
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	3.1	-1.0	-1.8	-0.4	-0.6	-1.2	-0.4	0.1	-1.3	-1.4
Blood clot in the leg (DVT)	0.7	0.8	1.8	-0.9	0.7	-1.0	-0.9	-1.1	-1.4	-1.1	-0.2	0.4
Medication: Paracetamol	1.0	1.6	2.9	-1.6	-0.9	-0.9	-1.3	-1.7	-1.1	-1.2	0.8	-1.6
Headache pain in last month	0.5	0.8	1.8	-1.1	-0.3	-0.9	-0.8	-1.2	-0.3	-1.3	-0.5	-1.0
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	2.2	0.9	0.3	1.2	0.0	1.2	1.5	1.3	0.1	0.9
Glaucoma (self-reported)	0.8	0.9	2.3	1.0	0.0	0.1	1.5	1.0	1.3	0.8	1.1	-0.9
Gout (self-reported)	1.3	1.8	4.5	-1.6	0.7	-0.9	-1.3	-1.4	-2.1	-1.2	1.4	-0.8
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	6.6	1.7	-0.5	0.5	2.3	1.0	1.7	0.3	-2.6	0.9
Medication: Amlodipine	1.2	1.7	3.5	1.1	-0.7	-1.5	-0.6	1.6	-1.4	-0.4	1.9	-1.7
Medication: Ventolin 100micrograms inhaler	1.1	1.4	4.4	-0.5	0.7	-2.1	-0.2	-0.4	-1.7	-2.0	0.1	-0.2
Birth weight	0.5	1.2	3.6	1.9	0.3	0.5	0.4	1.4	0.6	0.7	1.9	0.3
Chronic bronchitis/emphysema (mother)	0.9	1.0	1.7	-1.3	-0.9	-1.0	-0.3	-1.0	-1.1	-0.6	-1.3	-1.1
High blood pressure (siblings)	0.8	1.2	3.8	-0.4	-0.8	1.8	-0.3	-0.4	1.4	-0.2	0.7	2.0
Forced vital capacity (FVC), Best measure	0.6	2.4	8.9	0.7	-1.9	3.0	0.5	0.5	2.1	1.0	0.3	1.6
Body fat percentage	0.5	2.0	6.4	-1.3	0.6	-2.5	0.4	-1.8	-1.1	-1.9	-0.2	-0.9
Leg fat percentage (right)	0.5	1.8	6.1	-0.6	1.2	-2.5	-0.2	-1.1	-1.5	-2.0	0.5	-0.8
Arm fat-free mass (right)	0.1	0.4	1.6	-0.7	-0.6	0.3	0.0	-1.3	0.8	0.3	-0.2	0.0
Exposure to tobacco smoke outside home	1.8	2.4	5.9	-1.2	0.4	-2.3	-1.1	-1.4	-2.4	-1.7	-1.1	-1.3
Comparative body size at age 10	0.2	0.5	3.3	0.6	-0.2	0.7	0.0	0.3	0.4	-0.3	1.8	-0.5
Number of full brothers	0.2	0.2	0.7	-0.4	-0.3	0.5	0.2	-0.9	0.2	-0.4	-0.4	0.4
Worry too long after embarrassment	2.4	4.0	11.0	-3.3	-1.4	-2.0	-2.1	-2.4	-0.5	-1.8	-0.1	-2.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	5.9	-2.4	-0.1	-0.7	-0.3	-1.9	-1.1	-0.7	-0.7	0.5
Wheeze or whistling in the chest in last year	1.1	1.9	4.0	-1.2	1.4	-1.3	-1.6	-1.2	-2.0	-1.1	1.7	0.1
Number of children fathered	0.3	0.3	1.7	-0.1	1.3	0.3	-0.4	-0.3	-0.3	-0.1	0.4	0.9
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.8	4.3	2.0	0.8	0.7	1.5	2.1	1.5	1.0	-1.1	0.1
Age at first live birth	0.8	1.3	4.7	1.0	-1.0	2.2	0.1	1.2	1.2	1.6	0.1	0.3
Pulse wave peak to peak time	3.0	3.5	9.5	1.0	1.9	2.7	0.8	0.9	1.3	2.5	0.8	3.1
Health satisfaction	0.3	0.4	2.2	0.2	-0.0	0.6	0.4	0.3	0.1	-0.2	0.7	1.5
Shortness of breath walking on level ground	2.6	3.1	7.3	-1.7	0.0	-2.6	-1.4	-1.9	-1.7	-2.7	-0.1	-1.6
Qualifications: College or University degree	3.2	10.1	23.4	3.2	0.5	4.1	2.7	3.0	4.3	4.8	-1.2	2.1
Eye problems/disorders: None of the above	0.6	0.7	4.1	-1.0	2.0	-0.3	0.6	-0.8	-0.4	-0.1	0.0	0.6
Mouth/teeth dental problems: Loose teeth	1.6	1.9	5.2	-0.2	0.4	1.8	1.7	-0.4	0.9	2.3	-1.8	0.9
Emphysema/chronic bronchitis	0.4	0.5	1.2	-0.7	0.2	0.6	0.9	-0.9	0.3	0.4	-1.1	0.7
Medication for pain relief, constipation, heartburn	1.5	2.5	4.6	1.3	0.1	1.9	1.6	1.2	1.9	1.9	-0.9	2.2
Neck or shoulder pain in last month	1.5	2.1	5.8	-1.7	-0.9	-1.7	-0.1	-2.4	-1.1	-1.6	-0.8	-1.2
Medication: Blood pressure	1.4	2.4	6.3	-1.3	0.4	-2.0	-0.6	-1.9	-2.5	-2.1	0.5	-0.7
Angina (self-reported)	0.8	1.1	5.7	0.0	0.6	0.1	1.0	-0.2	0.4	2.4	-1.1	-1.3
Migraine (self-reported)	1.9	2.4	5.0	-1.2	0.2	1.6	0.7	-1.8	2.2	1.5	-2.1	1.4
Medication: Ibuprofen	1.0	1.2	5.7	-0.6	-1.0	-1.3	-0.3	-0.9	-0.7	-0.8	0.4	-2.4
Medication: Allopurinol	1.3	1.7	3.3	-1.2	0.7	-1.3	-1.2	-0.9	-1.8	-1.7	1.6	-0.5
Medication: Omeprazole	0.8	0.9	2.7	0.3	1.1	-0.2	-0.7	0.3	-1.6	-1.4	1.0	0.8
Medication: Seretide 50 evohaler	1.3	1.5	3.9	-2.0	-1.1	-0.8	-0.8	-1.9	-0.5	-1.5	0.2	-1.1
Mean time to correctly identify matches	1.8	3.4	12.9	-0.6	1.8	-2.8	-1.7	-0.2	-3.6	-1.1	1.3	-0.5
Heart disease (mother)	0.4	0.5	1.0	0.2	-0.8	0.9	-0.8	0.3	-0.2	1.0	0.9	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	0.8	0.8	0.9	-0.1	0.7	0.5	0.5	0.2	0.3	0.3
Whole body fat mass	0.3	1.4	3.6	-1.4	0.3	-1.9	0.2	-1.9	-0.8	-1.6	0.1	-0.7
Leg fat mass (right)	0.2	0.9	2.9	-0.7	0.8	-1.7	0.2	-1.3	-0.7	-1.3	0.4	-0.4
Arm predicted mass (right)	0.1	0.5	2.2	-0.9	-0.8	0.1	-0.1	-1.5	0.7	-0.0	-0.4	-0.2
Pulse rate, automated reading	0.7	2.3	6.3	2.5	0.9	0.6	1.8	1.4	2.0	0.3	-1.0	1.7
Alcohol intake frequency.	0.5	1.1	4.5	-1.2	-1.4	-0.4	-0.9	-2.1	-0.6	-0.4	-0.6	-0.7
Comparative height size at age 10	0.3	1.7	3.4	-1.2	-0.7	-1.3	1.9	-1.8	0.7	0.3	-1.8	-1.2
Number of full sisters	1.3	1.6	4.4	0.2	-0.0	-1.9	-1.1	0.3	-1.6	-2.1	-1.6	-0.3
Suffer from ‘nerves’	0.5	0.8	2.3	-0.9	-0.3	-1.5	-0.4	-0.8	-0.8	-1.5	0.3	-0.8
Overall health rating	1.0	2.2	4.1	-1.6	-1.4	-1.6	-1.2	-2.0	-1.7	-1.8	-0.8	-0.3
Chest pain or discomfort	1.3	1.8	5.4	-1.6	-0.7	-1.6	-0.3	-2.3	-1.4	-1.0	-0.4	-1.5
Had major operations	1.1	1.2	3.5	-1.6	-0.7	0.2	-1.2	-1.4	-1.0	-1.9	0.1	-0.5
Age at last live birth	0.7	1.0	1.8	1.3	-0.1	0.4	1.3	1.3	1.0	0.8	-0.9	-1.0
Family relationship satisfaction	0.5	0.7	2.6	-0.9	0.3	-0.5	-1.2	-0.4	-0.8	-0.1	1.6	0.3
Leg pain on walking	1.2	1.6	5.7	-0.9	-0.0	-1.4	1.1	-0.8	-0.6	-0.7	-1.6	-2.4
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	2.2	-0.6	0.2	-1.5	-0.0	-0.7	-0.6	-0.5	-0.1	0.5
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.5	0.7	-0.9	1.2	0.1	0.6	1.1	0.7	-0.2	0.8
Illness, injury, bereavement, stress in last 2 years	2.1	2.5	5.5	1.2	-0.8	2.3	1.5	1.4	2.2	1.7	0.6	1.7
Medication: Aspirin	0.5	0.6	2.5	0.1	-0.3	-0.7	0.3	-0.3	-0.1	0.1	-1.5	-1.6
Supplements: Vitamin C	0.5	0.6	1.3	-1.0	-0.4	-0.5	-1.1	-1.1	-0.8	-0.4	0.7	-0.8
Knee pain experienced in last month	0.4	0.6	2.9	1.7	-0.6	-0.4	0.9	0.7	0.1	-0.4	-0.0	0.6
Hypertension (Self-reported)	0.8	2.3	5.6	-0.4	-0.8	-2.4	-1.5	-0.4	-2.2	-2.3	0.4	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.8	3.2	11.9	-0.1	-0.4	3.1	0.3	-0.5	2.5	0.8	0.2	3.4
Illnesses of father: Heart disease	0.4	0.6	2.0	0.7	1.1	0.3	-1.4	0.9	0.1	-0.3	0.2	0.6
Illnesses of siblings: Diabetes	1.2	1.5	4.1	-2.0	-1.8	-0.3	-0.9	-1.8	-0.3	-0.7	-1.1	-0.5
Smoking status: Previous	2.0	2.9	7.4	-1.8	0.2	-0.8	-2.5	-1.4	-2.2	-1.6	2.7	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	5.2	-2.3	-1.1	-0.6	-1.1	-2.1	-1.3	-0.9	-0.7	-0.3
Whole body fat-free mass	0.1	0.5	1.1	-0.4	-0.9	0.8	0.3	-1.0	1.1	0.3	0.3	-0.2
Leg fat-free mass (right)	0.1	0.7	2.7	-0.3	-1.0	1.0	0.8	-1.0	1.6	0.4	0.1	0.3
Arm fat percentage (left)	0.2	0.7	2.5	-0.3	0.3	-1.6	0.7	-0.9	-0.5	-1.3	0.2	-0.3
Average weekly red wine intake	0.3	0.4	1.0	0.3	-0.5	0.5	-0.9	1.0	0.0	-0.2	0.8	-0.6
Handedness (chirality/laterality): Left-handed	0.6	0.8	2.9	-0.0	-1.2	-0.7	0.3	0.4	-0.0	0.3	-1.7	-1.2
Mood swings	2.5	4.6	9.3	-3.0	-0.1	-1.1	-3.1	-2.5	-2.3	-2.1	2.2	-0.8
Loneliness, isolation	1.3	1.8	2.7	-1.3	-1.5	-1.5	-1.6	-1.1	-1.4	-1.6	0.8	-0.9
Long-standing illness, disability or infirmity	0.7	1.0	2.5	-0.6	-0.8	-1.3	-0.1	-1.2	-0.9	-1.1	-1.6	-0.7
Ever had bowel cancer screening	1.3	1.5	3.4	1.4	-0.1	1.4	1.1	0.9	1.9	1.2	-1.4	-0.7
Diabetes diagnosed by doctor	1.9	3.1	7.9	-1.0	-1.4	-2.1	-2.7	-0.7	-2.8	-1.6	0.1	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.3	-0.7	0.1	0.2	-0.5	-0.8	1.1	-0.1	-1.1	-0.2
Friendships satisfaction	0.8	1.0	3.1	-0.7	0.7	0.8	-1.4	0.1	-0.6	0.9	1.8	0.9
Qualifications: nursing, teaching	1.1	1.8	4.4	1.1	-1.8	1.8	-0.2	0.8	1.6	2.1	0.7	-0.4
Commuting to job workplace: Walk	0.5	0.5	2.5	-1.6	-0.2	-0.2	0.3	-1.1	-0.3	-0.4	-0.5	-0.7
Eye problems/disorders: Cataract	0.5	0.6	2.3	1.5	-0.7	0.5	0.1	1.1	0.6	-0.1	-0.4	0.6
Mouth/teeth dental problems: Mouth ulcers	1.3	2.0	6.5	0.5	0.1	1.8	1.3	0.3	2.5	0.6	-1.7	1.9
Medication for cholesterol	0.6	0.9	2.4	1.5	0.9	0.6	1.1	1.5	0.5	0.6	0.6	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.5	0.2	-0.7	-0.2	-0.2	0.4	-0.7	-0.4	-0.6	-0.6
Back pain experienced in last month	0.5	0.7	2.0	-0.7	-1.3	-0.4	0.8	-0.9	0.2	-0.2	-1.4	-0.7
Mineral and other dietary supplements	0.5	0.7	1.9	-0.8	0.4	0.9	-1.4	-0.6	0.5	-0.5	0.7	1.0
Breast cancer (self-reported)	1.6	1.9	5.0	-0.6	-0.4	2.2	0.7	-1.0	1.5	1.5	0.8	2.2
Asthma (self-reported)	0.4	0.7	2.5	-1.5	0.0	-0.5	-0.7	-1.6	-0.5	0.3	0.7	-0.2
Osteoporosis (self-reported)	1.1	1.4	3.6	0.7	-1.1	1.4	0.2	1.1	1.9	1.0	-1.6	0.8
Osteoarthritis (self-reported)	0.9	1.1	4.3	1.8	-0.2	0.5	2.1	1.2	0.6	0.7	0.0	0.1
Medication: Aspirin	0.6	0.8	2.5	0.5	-0.3	-0.6	1.0	0.1	0.4	0.5	-1.6	-1.6
Medication: Gliclazide	2.1	2.3	8.3	0.6	1.9	-2.9	0.0	1.0	-2.5	-1.0	-0.2	-0.4
Illnesses of father: None of the above (group 1)	1.3	1.6	4.1	0.9	-1.7	0.0	1.9	0.9	1.2	0.7	-0.7	-2.0
Smoking status: Current	2.4	3.7	8.3	-2.0	0.7	-2.9	-1.3	-1.6	-2.4	-2.3	-1.2	-2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	3.0	1.3	-0.3	1.1	0.2	1.7	1.0	0.5	0.4	0.9
Whole body water mass	0.1	0.5	1.3	-0.4	-1.0	0.9	0.3	-1.1	1.1	0.3	0.4	-0.0
Leg predicted mass (right)	0.1	0.7	2.6	-0.2	-0.9	0.9	0.8	-0.9	1.6	0.3	0.2	0.3
Arm fat mass (left)	0.2	0.6	2.0	-0.8	-0.0	-1.2	0.4	-1.4	-0.2	-1.1	0.3	-0.3
Number of self-reported non-cancer illnesses	1.2	2.0	5.8	-2.1	-0.7	-1.4	-1.2	-2.4	-1.2	-1.1	-0.7	-1.0
Average weekly champagne plus white wine intake	3.5	4.8	9.3	1.3	1.9	2.5	2.4	1.4	3.0	1.9	-1.2	3.0
Miserableness	2.7	4.7	12.5	-3.5	0.3	-1.9	-2.6	-3.0	-1.5	-2.8	0.5	-0.5
Guilty feelings	1.4	2.1	4.9	-2.2	-0.0	-1.4	-1.2	-2.0	-1.8	-1.8	0.4	-0.2
Wears glasses or contact lenses	1.3	1.4	5.8	-0.7	-2.4	0.3	-0.9	-0.9	1.2	-0.7	-0.8	-1.5
Ever taken oral contraceptive pill	0.7	0.8	2.9	-0.3	-0.1	-1.4	-0.6	-0.1	-1.7	-0.6	-0.9	-0.6
Hearing aid user	0.9	1.0	4.5	-2.1	0.4	-0.1	0.1	-1.9	0.3	-0.2	-0.5	0.8
Mother’s age at death	1.9	2.4	6.2	1.4	2.5	1.4	0.8	1.5	0.3	1.1	1.6	2.1
Financial situation satisfaction	1.1	1.3	4.7	-2.2	-1.3	0.6	-1.1	-1.7	0.1	-0.0	0.1	-1.1
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.8	0.9	-0.2	0.5	0.5	0.9	0.3	0.8	-1.0	-1.7
Commuting to job workplace: Public transport	0.9	1.1	4.4	-0.0	2.1	-0.6	-0.7	-0.2	-0.9	-0.0	1.6	0.8
Eye problems/disorders: Glaucoma	0.6	0.7	2.2	-0.1	-0.4	1.3	0.6	-0.0	1.5	0.7	1.3	0.3
Medication: Blood pressure	0.6	1.1	2.7	-0.4	-0.0	-1.1	-1.6	-0.4	-1.4	-1.5	0.9	0.6
Pain type(s) experienced in last month: Hip pain	1.7	2.1	6.3	-0.9	-0.2	-1.6	-0.4	-1.0	-2.1	-2.5	0.9	-1.7
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.8	0.3	-0.7	-1.5	0.3	-0.2	-1.3	-1.0	0.8	-1.7
High cholesterol (Self-reported)	0.5	1.0	2.8	-1.2	-1.4	-0.4	-0.5	-0.9	-0.0	0.4	-1.7	-1.0
Medication: Bendroflumethiazide	0.4	0.6	3.3	0.2	-0.6	-0.9	0.2	-0.2	0.0	-1.8	-0.2	0.9
Medication: Paracetamol	1.0	1.6	3.5	-1.5	-1.6	-0.3	-1.2	-1.9	-0.6	-1.0	0.7	-1.7
Medication: Lisinopril	1.9	2.5	6.3	-1.1	0.4	-1.8	-1.9	-1.3	-2.5	-2.4	0.8	-0.6
Medication: Atorvastatin	1.1	1.4	6.9	-1.1	-1.6	-0.2	-0.2	-0.6	0.3	1.0	-2.6	-0.6
Illnesses of father: High blood pressure	1.2	1.4	4.6	0.0	1.2	-0.1	-1.6	-0.4	-0.8	-1.1	1.6	2.1
Alcohol drinker status: Never	2.5	3.0	6.9	2.1	-0.8	0.7	1.7	1.9	2.6	2.2	-1.7	-0.9
Ever smoked	1.2	2.1	5.2	-1.1	-0.1	-0.8	-2.0	-0.5	-2.2	-1.5	2.3	-0.8
Basal metabolic rate	0.1	0.3	1.3	-0.5	-0.6	0.3	0.3	-1.1	0.8	0.0	0.3	-0.2
Leg fat percentage (left)	0.5	1.7	6.0	-0.8	1.1	-2.4	0.0	-1.2	-1.4	-1.8	0.4	-0.9
Arm fat-free mass (left)	0.1	0.6	1.8	-0.7	-0.6	0.9	0.2	-1.4	1.0	0.4	0.6	0.5
Number of operations (self-reported)	0.3	0.5	0.9	-0.7	0.1	0.4	-0.8	-0.8	-1.0	-0.9	0.0	-0.6
Average weekly beer plus cider intake	0.7	1.0	3.8	-0.3	0.2	-0.6	-1.0	-0.6	-1.2	-2.0	1.0	1.1
Irritability	4.8	8.0	19.5	-4.4	-1.4	-1.8	-3.2	-4.2	-2.2	-2.0	0.5	-3.3
Risk taking	1.4	2.0	6.9	-2.2	-0.4	-0.1	-0.6	-2.6	-0.1	0.8	-2.2	0.1
Ever had prostate specific antigen (PSA) test	2.8	3.2	7.4	-1.4	0.5	-2.7	-1.6	-1.2	-2.4	-2.5	0.4	-1.8
Fractured/broken bones in last 5 years	0.8	1.0	4.4	0.1	2.1	-0.4	1.0	0.4	-0.5	1.3	-1.0	-0.5
Age started oral contraceptive pill	1.7	2.1	4.5	0.8	-1.2	2.1	1.5	0.7	2.0	2.1	1.2	-0.3
Diastolic blood pressure, automated reading	0.7	2.0	6.0	0.9	0.3	2.4	1.4	0.6	0.7	1.3	1.1	2.4
Ever depressed for a whole week	0.3	0.4	0.9	-0.9	0.3	-1.0	-0.9	-0.4	0.0	-0.7	0.1	0.2
Unable to work because of sickness or disability	1.8	2.4	4.2	-2.1	-0.2	-1.5	-1.1	-2.0	-1.9	-1.3	-0.3	-1.9
Commuting to job workplace: Cycle	0.3	0.3	1.4	-0.2	-0.7	1.2	-0.1	0.2	0.7	0.5	0.5	-0.5
Myopia	0.2	0.2	0.9	-0.1	-0.2	-0.6	-0.7	0.1	-0.3	-0.4	-0.2	-0.9
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.6	0.4	0.6	1.6	0.5	0.4	1.3	1.3	0.1	1.2
Cholesterol lowering medication	0.8	1.2	3.6	-0.7	0.1	-1.9	-1.1	-0.3	-1.1	-1.1	-1.4	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	2.3	0.7	0.5	0.5	-0.5	0.7	-1.0	-0.9	1.5	1.2
Pain experienced in last month	1.0	1.7	3.8	1.1	0.8	1.9	0.1	1.5	1.1	1.9	0.7	1.6
Supplements: Calcium	0.9	1.0	5.3	-0.0	-0.6	-1.3	0.7	-0.1	-0.5	-0.7	-2.3	-0.2
Basal cell carcinoma (self-reported)	1.2	1.4	5.8	-0.8	-2.4	-0.2	-0.6	-0.9	-0.2	-0.1	0.7	-2.0
Heart attack/myocardial infarction (self-reported)	0.7	0.9	3.6	-1.0	1.9	-0.0	-0.0	-0.9	-0.0	0.2	-1.4	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	2.0	-0.9	0.3	-0.8	-0.8	-1.2	-1.4	-0.9	0.3	0.2
Heart disease (siblings)	1.2	1.5	5.1	-1.2	-0.0	-1.4	-0.7	-1.2	-0.8	-2.2	-1.1	-0.9
Alcohol drinker status: Previous	1.6	1.9	5.0	-0.3	-0.0	-1.6	-1.5	-0.7	-2.2	-1.9	1.2	-1.3
Pack years of smoking	2.2	3.3	7.7	-1.7	-2.3	-1.1	-1.7	-2.3	-1.5	-2.8	-0.4	-1.4
Impedance of whole body	0.3	1.7	4.0	-1.3	-0.0	-2.0	-0.8	-0.4	-1.9	-1.6	-1.0	-1.1
Leg fat mass (left)	0.2	0.9	2.7	-0.7	0.8	-1.6	0.4	-1.3	-0.6	-1.2	0.4	-0.5
Arm predicted mass (left)	0.1	0.5	1.4	-0.5	-0.7	0.8	0.3	-1.2	1.2	0.4	0.4	0.3