Hub : Genes

C1QTNF7

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1440 0.0290 4.1e-14 0.110 0.124 0.180 0.160 0.180 2.7e-13 6.5e-15 2.3e-21 4.7e-19 2.1e-21
2 GTEx Artery Aorta 0.2890 0.0720 1.3e-05 0.109 NA 0.048 NA 0.068 1.3e-06 NA 1.1e-03 NA 1.3e-04
3 GTEx Skin Sun Exposed Lower leg 0.1010 0.0340 6.5e-04 0.066 NA 0.015 NA 0.030 3.5e-06 NA 1.8e-02 NA 1.6e-03
4 METSIM Adipose 0.1037 0.0273 2.6e-09 0.054 0.075 0.070 0.072 0.068 1.4e-08 2.7e-11 1.3e-10 6.3e-11 2.3e-10
5 NTR Blood 0.1291 0.0211 0.0e+00 0.135 0.149 0.163 0.157 0.160 3.7e-41 8.7e-46 2.5e-50 2.7e-48 2.8e-49
6 TCGA Head and Neck Squamous Cell Carcinoma 0.0396 0.0198 3.7e-04 0.041 0.042 0.023 NA 0.033 2.0e-05 1.6e-05 1.0e-03 NA 1.2e-04
7 TCGA Lung Adenocarcinoma 0.0394 0.0203 4.1e-03 0.026 0.010 0.006 NA 0.011 4.4e-04 2.3e-02 5.1e-02 NA 1.5e-02
8 TCGA Pancreatic Adenocarcinoma 0.1380 0.0670 4.7e-03 0.005 -0.005 0.004 NA 0.007 1.8e-01 5.7e-01 2.2e-01 NA 1.6e-01
9 TCGA Prostate Adenocarcinoma 0.1032 0.0394 4.6e-05 0.012 0.038 0.025 NA 0.024 1.8e-02 6.3e-05 1.0e-03 NA 1.4e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.1 0.2 0.9 0.2 0.9 -0.4 -0.2 -0.1 0.8 0.0 -0.5 0.2
Bipolar Disorder or Schizophrenia 0.4 1.1 4.7 0.1 2.2 -1.1 -0.0 -0.4 -0.2 -0.9 -0.3 1.6
Depressed Affect (Nagel 2018) 3.7 7.7 15.7 -4.0 -0.7 -3.0 -3.3 -3.5 -2.6 -3.0 0.7 -2.3
Depression (Nagel 2018) 4.6 6.9 11.3 -3.3 -0.9 -2.5 -3.4 -2.9 -3.2 -2.5 2.6 -1.3
Intelligence (Savage-Jansen 2018) 1.3 4.1 9.2 1.3 -1.8 3.0 2.0 1.2 2.9 2.8 0.7 0.3
Neuroticism (Nagel 2018) 4.9 11.6 23.7 -4.9 -1.9 -3.2 -4.0 -4.2 -3.3 -3.5 0.9 -3.0
Schizophrenia (2018) 0.6 1.2 4.0 -0.0 2.0 -1.2 0.2 -0.4 -0.9 -1.2 0.1 1.8
Schizophrenia vs Biploar Disorder 0.2 0.3 1.0 -0.2 -1.0 0.0 -0.6 -0.3 -0.6 -0.7 0.2 -0.2
Worry (Nagel 2018) 1.6 3.3 5.7 -2.1 -1.3 -1.6 -2.3 -1.6 -1.9 -2.4 1.6 -1.3
Alzheimer’s Disease (in mother) 2.2 2.5 7.3 -1.1 2.5 -0.7 -1.0 -1.3 -1.5 -1.4 2.7 0.9
Alzheimer’s Disease (in father) 1.1 1.2 3.9 0.7 0.3 0.6 1.3 0.0 1.4 2.0 -1.2 -1.1
Alzheimer’s Disease (including proxy) 1.1 1.6 7.5 -0.8 2.7 -1.1 -0.1 -1.1 -1.3 -0.9 1.3 0.2
Crohns Disease (2017) 1.2 2.7 9.4 -3.0 -1.0 -0.2 -1.5 -3.1 -1.3 0.3 0.9 -0.6
Irritable Bowel Disease (IBD) 0.6 1.5 3.6 -1.5 -1.5 0.7 -0.3 -1.9 0.6 1.8 -0.5 -0.8
Ulcerative Colitis (UC) 1.1 2.0 5.0 1.3 -0.7 1.2 1.4 0.8 2.2 2.2 -1.3 -0.2
Major Depression (MDD) 5.4 6.6 14.8 -2.3 -0.8 -3.1 -2.3 -2.9 -2.7 -3.9 0.1 -2.8
Reaction Time 1.6 3.0 11.7 -0.3 1.2 -3.1 -1.4 -0.1 -3.4 -1.2 0.3 -0.9
Verbal and Numeric Reasoning (VNR) 1.5 3.6 10.0 0.2 -2.7 3.2 0.4 0.1 2.3 2.8 0.9 0.6
Breast Cancer 0.7 1.6 3.5 1.9 0.7 1.3 1.3 1.8 0.6 1.2 0.8 1.1
Ovarian Cancer 0.7 1.0 3.2 1.3 -0.7 -0.3 0.9 1.5 0.6 -0.2 -1.8 -0.1
Prostate Cancer 1.1 1.5 4.6 2.2 0.2 -0.5 1.2 2.0 -0.2 0.9 0.3 -1.5
Age at First Birth 2.7 3.9 9.4 0.7 -3.1 2.7 1.6 0.6 2.8 2.3 -1.1 -0.8
Bipolar Disorder (2011) 0.5 0.5 2.3 0.5 1.0 0.1 -0.0 0.3 0.3 0.3 0.4 1.5
Body Mass Index (BMI) (2010) 0.7 1.0 2.3 1.5 1.3 0.6 1.3 1.2 0.5 -0.2 0.0 1.0
Coronary Artery Disease (CAD) 1.5 1.8 4.5 -1.1 -0.0 -2.1 -1.3 -1.0 -2.1 -1.4 -0.3 -1.1
Crohns Disease (2012) 0.6 0.9 2.2 -1.1 0.7 -1.0 -0.8 -0.8 -1.5 -0.6 1.2 0.4
Mean Putamen Volume 0.8 1.0 3.3 -1.7 0.5 0.3 -1.1 -1.8 0.2 1.0 0.3 -0.1
Fasting Glucose 0.3 0.3 1.5 -0.7 -1.2 -0.1 0.2 -0.6 0.2 -0.2 -0.7 -0.4
HbA1C 0.9 1.0 4.2 -2.0 -0.3 -0.5 -0.6 -1.8 -0.2 -0.2 -0.9 -0.3
HDL Cholesterol 0.5 0.9 3.1 -0.4 0.3 -0.3 1.6 -0.5 0.9 0.8 -1.7 0.7
LDL Cholesterol 0.3 0.4 1.7 0.7 1.3 -0.5 0.2 0.4 0.4 -0.4 -0.8 0.3
Lupus 0.5 0.7 2.3 0.3 1.0 0.3 1.3 -0.2 -0.1 1.5 -1.1 0.2
Neuroticism (2016) 2.3 3.3 12.2 -3.2 -1.1 -0.4 -1.7 -3.5 -0.9 -0.7 1.0 -0.9
Primary Biliary Cirrhosis 2.3 3.3 6.5 0.8 -0.7 -1.8 -2.0 0.6 -2.3 -2.5 2.5 -1.7
Rheumatoid Arthritis 0.1 0.2 0.6 -0.0 -0.2 -0.2 0.1 -0.6 0.0 0.7 -0.8 0.0
Schizophrenia (2014) 0.4 0.8 2.1 -0.2 1.3 -0.7 -0.1 -0.8 -0.7 -1.3 0.1 1.5
Triglycerides 0.4 0.7 4.6 -0.2 2.1 0.3 0.8 -0.2 -0.1 0.3 -0.3 0.6
Type 2 Diabetes (T2D) (2012) 0.8 0.9 2.4 1.3 -0.3 1.2 -0.1 1.5 0.8 1.4 -0.1 -0.2
Ulcerative Colitis 1.1 1.6 4.4 0.0 -2.1 1.4 -0.2 0.1 1.8 1.8 -0.9 -0.5
Blood Eosinophil Count 0.2 1.3 4.5 -2.1 -0.8 -0.3 -1.2 -1.2 -0.0 -0.9 1.1 -1.0
Blood Platelet Count 0.0 0.4 1.6 -0.1 -0.0 -1.2 0.4 -0.2 -0.7 -0.8 0.4 -0.9
Blood Red Count 2.4 23.6 85.9 -8.4 -2.9 -1.9 -3.5 -9.3 -2.3 -2.8 -2.1 -3.7
Blood White Count 0.8 5.8 19.3 -1.7 -1.2 -2.6 -2.1 -2.1 -2.7 -4.4 0.7 -2.2
Heel T-Score 0.2 1.5 5.6 -0.1 1.5 0.9 0.9 -0.2 1.8 2.4 -0.1 0.8
BMI 0.2 0.9 1.9 1.0 1.1 -1.2 0.8 0.5 -0.1 -1.4 1.2 0.6
Height 0.3 5.5 21.6 -4.1 -1.8 0.5 0.6 -4.7 1.9 0.6 -1.8 -0.6
Waist Hip Ratio (WHR) 3.5 15.7 40.2 -1.9 -1.4 -6.3 -3.3 -2.1 -5.6 -5.3 -0.9 -4.5
Systolic Blood Pressure 0.5 2.3 9.1 0.0 0.5 -3.0 -0.6 0.9 -2.0 -2.3 -0.1 -0.8
Smoking Status 1.9 4.5 7.5 -2.6 0.2 -2.3 -2.0 -2.3 -2.6 -2.7 0.7 -2.0
Allergy or Eczema 0.3 0.9 1.9 1.2 0.2 0.7 1.0 1.4 0.8 0.9 0.8 1.2
Cardiovascular Disease 0.4 1.5 3.5 0.2 -1.9 -1.8 -0.4 0.3 -1.4 -1.8 -0.4 -1.0
Hypothyroidism (self reported) 0.5 1.2 4.0 0.9 -0.5 0.2 1.8 0.4 1.3 -0.2 -2.0 0.7
Respiratory disease 0.3 0.7 2.2 -1.3 0.7 -0.3 -0.2 -1.1 -0.6 0.1 1.5 -0.0
Type 2 Diabetes (T2D) (2018) 1.3 2.4 6.5 -1.5 -0.4 -2.1 -2.2 -1.3 -2.5 -1.4 -0.1 -0.0
Lung FEV1/FVC ratio 1.3 6.4 18.6 3.9 3.5 -0.4 2.2 4.3 1.1 0.6 -0.3 2.2
Lung FVC 0.8 4.3 12.9 1.9 -0.4 3.6 1.2 2.1 3.0 2.0 0.4 1.6
Neuroticism 3.6 8.7 16.1 -4.0 -1.6 -3.0 -3.3 -3.2 -2.6 -3.4 0.7 -3.2
Chronotype (morning person) 0.4 0.8 2.5 1.6 0.3 -0.2 -0.3 0.8 -1.6 -0.2 1.0 -0.8
Hair Pigment 0.0 0.2 0.6 0.1 0.4 -0.8 0.0 0.0 -0.3 0.2 0.1 -0.7
Tanning 0.1 1.3 2.9 -0.6 -1.4 -1.3 -0.7 -0.9 -1.3 -1.7 -0.2 -1.3
Hand grip strength (left) 0.2 0.5 1.6 -0.7 -0.2 1.0 -0.1 -0.8 0.6 -0.1 1.2 0.8
Number of treatments/medications taken 1.0 1.8 5.9 -2.0 -0.7 -1.0 -1.2 -2.4 -1.2 -1.1 0.3 -0.7
Average weekly spirits intake 0.8 1.0 2.5 -1.0 -1.0 -0.7 -0.7 -1.6 -1.0 -0.9 -0.2 -1.3
Sensitivity / hurt feelings 1.3 2.2 9.3 -3.0 -0.5 -1.1 -1.2 -2.2 -0.8 -1.3 -0.7 -0.3
Frequency of depressed mood in last 2 weeks 4.6 6.4 13.3 -3.4 -1.1 -2.6 -3.6 -2.6 -3.0 -2.6 1.3 -0.8
Hearing difficulty/problems: Yes 0.3 0.5 1.2 0.5 1.1 -0.5 0.5 0.8 -0.7 0.8 0.2 -0.7
Relative age of first facial hair 0.5 1.1 3.1 -0.6 0.3 1.6 -0.1 -0.3 0.2 1.1 1.5 1.8
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 2.4 -0.8 -0.4 -1.1 -0.7 -0.9 -1.4 -1.6 -0.2 -0.5
Ever used hormone-replacement therapy (HRT) 0.4 0.6 2.0 -0.6 1.1 -0.3 1.4 -0.7 0.8 -0.1 -0.6 -0.0
Ever had hysterectomy (womb removed) 0.4 0.5 1.9 0.7 0.2 -0.5 1.4 0.3 -0.2 -0.7 -0.9 -0.4
Systolic blood pressure, automated reading 0.1 0.4 1.5 0.0 -0.3 -1.2 0.0 0.4 -0.9 -0.7 0.5 -0.4
Eye problems/disorders: Diabetes related eye disease 1.0 1.2 2.8 -0.5 -1.7 -0.9 -1.0 -0.2 -0.8 0.4 -1.4 -1.6
Angina 0.8 1.1 5.6 -0.1 0.6 -0.0 0.8 -0.3 0.3 2.4 -0.9 -1.4
Medication for hormone replacement therapy 1.0 1.1 2.8 -1.5 -0.1 1.5 -0.0 -1.7 1.0 0.5 -0.5 1.2
Vitamin and mineral supplements 0.2 0.3 0.7 0.5 0.1 0.7 0.2 0.4 0.9 -0.7 0.1 0.6
Supplements: Zinc 0.7 0.7 1.6 -0.2 -1.2 -0.9 -0.4 -0.7 -1.2 -0.4 1.2 -0.7
Medication: Co-codamol 0.4 0.5 1.2 0.3 0.6 -1.0 1.1 -0.3 -0.3 -0.7 -1.1 0.2
Medication: Metformin 2.2 3.1 7.2 -1.6 -1.1 -2.7 -2.0 -1.2 -2.2 -2.0 -0.6 -1.6
Diabetes (father) 0.2 0.2 0.7 -0.6 -0.0 -0.1 -0.9 -0.4 0.1 0.0 0.8 0.0
Diabetes (mother) 0.1 0.2 0.8 -0.4 0.9 -0.2 -0.3 0.2 -0.3 -0.4 0.5 0.1
Severe depression (siblings) 0.2 0.2 1.1 -0.5 0.2 -0.2 0.2 -0.6 0.1 -0.2 -0.2 1.1
Pack years adult smoking proportion 2.7 4.1 8.7 -2.1 -2.3 -1.3 -2.0 -2.6 -1.8 -2.9 -0.7 -1.5
Impedance of leg (right) 0.6 2.8 7.9 -1.5 0.4 -2.3 -1.7 -0.6 -2.8 -1.7 -0.9 -1.5
Leg fat-free mass (left) 0.1 0.4 1.5 0.0 -0.8 0.6 0.7 -0.8 1.2 0.0 0.2 0.2
Trunk fat percentage 0.5 2.1 6.6 -1.5 0.2 -2.6 0.4 -2.0 -1.0 -1.9 -0.6 -1.2
Hand grip strength (right) 0.5 1.5 4.0 -1.2 -1.4 2.0 -0.3 -1.1 1.3 1.1 0.9 1.0
Townsend deprivation index at recruitment 1.0 1.4 3.8 -0.2 0.7 -1.9 -0.1 -0.6 -1.0 -1.1 -1.4 -2.0
Current tobacco smoking 2.1 3.4 7.8 -2.0 0.3 -2.8 -1.0 -1.7 -2.2 -2.2 -1.0 -2.1
Average weekly fortified wine intake 0.6 0.7 2.4 0.6 0.2 -0.3 -1.2 0.8 -1.0 -0.4 1.6 0.2
Maternal smoking around birth 1.6 2.3 6.0 -1.2 0.7 -2.2 -1.0 -1.0 -2.3 -2.4 0.1 -0.8
Fed-up feelings 2.5 4.6 8.2 -2.8 0.8 -2.8 -1.9 -2.5 -2.3 -2.9 -0.6 -1.4
Frequency of unenthusiasm / disinterest in last 2 weeks 4.4 5.9 10.4 -3.2 -0.2 -2.8 -2.4 -2.9 -3.1 -2.9 1.5 -0.9
Relative age voice broke 0.7 1.1 4.6 1.1 0.1 0.9 0.4 1.2 0.2 -0.1 1.2 2.1
Taking other prescription medications 1.0 1.6 5.3 -2.3 0.5 -1.1 -0.8 -2.1 -1.0 -0.8 0.8 -0.2
Age when periods started (menarche) 0.4 1.0 5.0 0.4 -0.8 -0.8 -0.6 1.3 -0.2 -2.2 0.3 0.3
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 0.8 -0.3 -0.5 0.3 0.6 -0.9 0.4 0.0 -0.6 -0.9
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.8 3.0 -0.5 1.7 -0.0 1.3 -0.5 0.3 0.6 -0.7 0.9
Tinnitus: Yes, but not now, but have in the past 0.5 0.5 0.9 0.4 -0.9 -0.4 1.0 0.6 0.8 -0.3 -0.9 -0.9
Qualifications: CSEs or equivalent 1.0 1.4 4.7 -1.9 -1.1 0.0 -1.0 -2.2 -0.9 -0.6 -0.2 -0.6
Serious illness, injury or assault to yourself 1.1 1.3 2.7 -1.4 0.3 -0.9 -0.7 -1.6 -1.6 -1.6 -0.3 -0.6
High blood pressure 0.6 1.7 4.9 -0.1 -0.8 -2.2 -0.8 -0.2 -1.9 -2.2 -0.0 -1.0
Hayfever, allergic rhinitis or eczema 0.6 1.4 3.3 0.8 0.8 0.3 1.1 1.1 1.6 0.9 -1.5 1.8
Multivitamins +/- minerals 0.3 0.4 1.1 -0.7 0.4 -1.0 -0.4 -0.4 -0.9 -0.1 0.5 0.1
Stomach or abdominal pain in last month 0.3 0.4 2.3 0.4 0.6 0.5 -0.1 -0.2 -0.2 -0.1 0.3 1.5
Supplements: Glucosamine 1.3 1.7 4.0 1.6 1.1 -0.4 2.0 1.7 0.9 1.2 -1.5 -0.1
Diverticular disease/diverticulitis (self-reported) 5.1 6.0 18.1 2.4 0.8 3.1 2.3 1.6 2.8 2.2 0.3 4.3
Medication: Atenolol 0.5 0.6 2.3 -0.3 0.9 -1.2 -0.3 -0.1 -1.5 -0.9 -0.4 -0.1
Medication: Levothyroxine sodium 1.1 1.8 4.6 1.5 -0.3 1.0 2.1 0.9 2.1 0.5 -1.4 1.1
Sitting height 0.7 4.8 17.1 -4.0 -1.6 -0.7 -1.3 -4.1 -0.7 -1.0 -1.4 -1.5
Chronic bronchitis/emphysema (father) 1.4 1.7 4.4 -1.8 0.0 -1.4 -1.0 -1.7 -2.1 -0.6 -0.7 -0.8
High blood pressure (mother) 0.4 0.6 3.0 -0.3 1.1 0.5 -1.7 0.3 -0.5 0.3 0.4 0.5
Body mass index (BMI) 0.1 0.3 0.9 -0.1 0.5 -0.9 0.4 -0.9 -0.1 -0.6 0.6 -0.2
Impedance of leg (left) 0.6 2.7 6.6 -2.0 0.5 -2.2 -1.6 -0.9 -2.6 -1.5 -1.0 -1.4
Leg predicted mass (left) 0.1 0.4 1.6 0.1 -0.8 0.7 0.8 -0.7 1.3 -0.0 0.3 0.3
Trunk fat mass 0.4 1.9 4.9 -1.6 -0.1 -2.2 0.2 -2.1 -0.8 -1.7 -0.2 -1.2
Waist circumference 0.3 1.1 4.5 -0.5 -0.1 -2.1 -0.2 -1.1 -1.0 -1.5 0.2 -0.7
Number of incorrect matches in round 0.3 0.5 1.9 0.4 0.3 -0.5 -0.6 0.5 -0.2 -1.2 1.4 -0.2
Past tobacco smoking 2.1 3.9 8.6 2.0 -0.5 1.4 2.9 1.4 2.8 1.9 -2.6 0.5
Alcohol usually taken with meals 1.0 1.6 4.3 -1.4 0.7 1.7 -0.9 -0.9 0.4 2.1 1.3 1.1
Nervous feelings 0.2 0.4 2.2 -0.9 -0.1 0.7 -0.2 -0.4 -0.1 0.2 1.5 0.5
Frequency of tenseness / restlessness in last 2 weeks 2.9 4.5 9.7 -2.1 1.6 -2.7 -2.2 -1.4 -2.9 -3.1 1.3 -0.6
Hearing difficulty/problems with background noise 0.6 0.9 3.2 -1.8 0.8 -0.6 -0.2 -1.7 -0.7 0.2 -0.8 -0.0
Hair/balding pattern: Pattern 2 0.6 0.8 2.7 0.2 -0.5 0.9 0.6 -0.6 1.6 1.3 -0.6 -0.4
Had menopause 1.0 1.3 4.0 0.5 -0.7 1.4 1.3 -0.1 2.0 1.3 -1.0 0.5
Had other major operations 0.9 1.1 2.3 -1.3 -0.4 -0.7 -0.8 -1.5 -1.2 -0.9 -0.8 -1.3
Forced vital capacity (FVC) 0.5 1.7 5.6 1.1 -1.5 2.4 0.1 1.0 1.9 0.6 0.3 1.2
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 0.9 -1.0 1.0 0.4 0.1 -0.9 0.1 0.5 0.0 0.3
Ever unenthusiastic/disinterested for a whole week 0.7 0.8 2.2 -0.9 1.1 -0.8 0.9 -0.6 0.9 0.9 -1.5 0.1
Qualifications: None of the above 3.1 6.6 16.0 -1.9 0.1 -3.3 -2.6 -1.4 -4.0 -3.8 1.4 -1.9
Financial difficulties in last 2 years 1.9 2.5 5.2 -1.4 1.4 -2.2 -2.1 -1.0 -2.3 -1.6 -0.4 -0.7
Mouth/teeth dental problems 0.4 0.6 1.5 1.2 1.0 0.4 0.4 1.1 0.2 0.3 1.1 0.6
Heart attack 0.7 0.8 2.9 -1.1 1.7 -0.1 -0.1 -1.0 -0.1 0.2 -1.4 -0.8
Allergy 0.2 0.4 1.6 -0.1 -0.7 0.0 -0.7 -0.1 -0.7 -0.5 0.8 -1.2
Pain all over the body in last month 0.9 0.9 2.7 -0.4 0.1 -1.6 0.1 0.2 -0.6 -1.6 -0.8 -1.4
Diabetes (self-reported) 1.5 2.4 5.8 -1.4 -1.4 -1.6 -2.2 -1.4 -2.4 -1.1 -0.3 -1.0
Hayfever/allergic rhinitis (self-reported) 1.6 2.2 6.5 1.2 2.0 0.6 1.7 1.2 1.5 1.0 -0.2 2.5
Medication: Ramipril 1.6 2.1 6.1 -0.6 1.8 -2.3 -0.8 -0.4 -1.6 -2.5 0.3 -0.2
Medication: Simvastatin 1.2 1.8 5.4 -0.9 0.7 -2.3 -0.6 -1.0 -1.8 -1.1 -0.9 -1.6
Fluid intelligence score 1.1 2.2 7.6 -0.1 -2.0 2.8 -0.7 0.1 1.8 2.0 0.1 0.6
Illnesses of siblings 0.7 0.9 2.1 1.4 1.1 -0.9 0.3 1.4 -0.9 0.5 0.1 -1.0
Neuroticism score 3.4 7.2 12.3 -3.5 -1.0 -3.1 -2.9 -2.8 -2.6 -3.5 0.7 -2.5
Weight 0.1 0.5 2.2 -0.9 -0.3 -0.9 0.2 -1.5 0.1 -0.8 0.3 -0.5
Impedance of arm (right) 0.1 0.7 2.3 -0.7 -0.6 -1.0 -0.3 -0.0 -1.1 -1.5 0.1 -0.7
Arm fat percentage (right) 0.2 0.6 1.9 -0.4 0.2 -1.4 0.7 -1.0 -0.3 -1.2 0.5 -0.4
Trunk fat-free mass 0.1 0.4 0.8 -0.5 -0.9 0.7 -0.0 -0.9 0.8 0.4 0.4 -0.6
Hip circumference 0.1 0.6 1.9 -0.0 0.1 0.5 1.3 -0.5 1.4 0.3 0.6 0.8
Time employed in main current job 1.2 1.4 3.8 0.1 -1.4 2.0 -0.3 -0.1 0.9 1.5 1.8 -0.4
Alcohol intake versus 10 years previously 0.6 0.9 2.5 0.4 1.4 0.8 -0.3 0.1 -1.5 -0.2 1.6 0.8
Father’s age at death 2.6 3.5 6.4 2.5 1.0 1.9 2.4 2.2 1.7 1.7 0.2 2.0
Worrier / anxious feelings 0.8 1.5 4.8 -0.9 -0.6 -1.1 -1.2 -0.4 -1.3 -2.2 1.1 -1.5
Frequency of tiredness / lethargy in last 2 weeks 2.5 4.1 10.3 -2.3 0.3 -2.5 -1.8 -2.2 -2.5 -3.2 -0.5 -0.6
Falls in the last year 0.2 0.3 1.2 -0.5 -0.3 -1.1 -0.2 -0.1 -0.6 -0.9 0.0 -0.4
Hair/balding pattern: Pattern 3 0.5 0.7 3.2 0.1 0.8 -0.3 1.0 0.5 -0.3 -0.1 -1.8 1.1
Number of live births 1.2 1.7 5.4 1.7 1.6 -0.2 2.3 1.6 1.0 0.6 0.3 0.2
Forced expiratory volume in 1-second (FEV1) 0.7 2.3 5.5 1.8 -0.8 2.4 0.2 1.8 2.0 1.0 0.5 1.6
Pulse rate 0.5 0.8 1.6 1.1 0.7 -1.2 1.3 0.4 0.5 -0.9 -1.0 0.2
Happiness 1.0 1.2 4.8 -1.1 -0.5 0.7 -1.7 -0.3 -0.0 0.9 2.2 0.7
Noisy workplace 0.7 0.8 2.1 -0.4 0.0 -1.3 -0.4 -0.6 -1.4 -0.6 -1.0 -1.3
Qualifications: A levels/AS levels or equivalent 1.9 4.2 9.9 2.4 -0.7 2.4 1.3 2.5 2.5 3.1 0.2 1.2
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 1.7 0.1 -0.9 -0.9 -1.2 -0.1 -1.3 -1.0 -0.0 -1.0
Mouth/teeth dental problems: Dentures 1.2 2.0 5.9 -1.1 0.5 -2.4 -0.3 -0.8 -2.0 -2.0 0.2 -1.3
Asthma 0.4 0.8 3.0 -1.6 -0.1 -0.5 -0.7 -1.7 -0.5 0.5 0.5 -0.3
Medication: Ibuprofen (e.g. Nurofen) 1.0 1.2 5.9 -0.4 -0.9 -1.5 -0.6 -0.4 -0.9 -0.8 0.5 -2.4
Medication: Cholesterol lowering 0.5 0.8 1.3 -1.0 -1.0 -0.7 -0.0 -1.1 -0.8 -0.4 -1.1 -1.1
Depression (self-reported) 2.1 2.5 5.8 -2.3 -0.0 -0.5 -2.1 -2.4 -1.6 -1.3 1.3 0.5
Medication: Lansoprazole 0.3 0.4 1.0 -0.2 -0.8 0.4 -1.0 -0.7 0.2 0.6 -0.7 0.0
Prospective memory result 0.6 0.7 1.6 0.6 1.0 -1.3 1.1 0.7 -0.3 -0.6 -0.3 -1.2
Lung cancer (father) 1.0 1.1 4.8 0.6 -0.6 -1.4 -0.7 -0.1 -1.0 -0.7 0.6 -2.2
Illnesses of mother 0.9 1.2 2.6 0.1 -1.6 0.1 1.6 -0.3 1.5 -0.4 -1.4 -0.8
Forced expiratory volume in 1-second (FEV1), Best measure 1.0 3.2 8.2 1.7 -1.0 2.9 1.0 1.6 2.5 1.4 -0.0 2.1
Pulse wave Arterial Stiffness index 2.8 3.2 8.0 -1.1 -1.9 -2.5 -0.7 -1.0 -1.2 -2.5 -0.9 -2.8
Impedance of arm (left) 0.2 0.8 1.8 -0.7 -0.6 -1.3 -0.3 0.1 -1.1 -1.3 -0.9 -0.7
Arm fat mass (right) 0.1 0.6 1.8 -0.7 -0.1 -1.2 0.4 -1.4 -0.2 -1.0 0.4 -0.4
Trunk predicted mass 0.1 0.4 0.9 -0.5 -0.9 0.7 0.0 -0.9 0.8 0.4 0.3 -0.5
Standing height 0.1 1.3 4.2 -2.1 -1.6 -0.1 -0.3 -1.8 0.5 -0.3 -0.7 -1.0
Length of working week for main job 1.0 1.1 2.1 -1.4 0.5 -1.2 -0.9 -1.4 -1.4 -0.8 -0.7 -0.7
Exposure to tobacco smoke at home 3.0 3.4 7.5 -1.4 -0.2 -2.7 -1.6 -1.7 -2.3 -2.2 0.5 -2.3
Breastfed as a baby 1.7 2.2 8.2 2.5 0.9 0.0 0.5 2.9 0.6 1.0 -1.5 0.5
Tense / ‘highly strung’ 4.2 6.9 13.7 -3.0 -0.1 -3.2 -2.7 -2.8 -3.7 -3.3 1.5 -1.0
Seen doctor (GP) for nerves, anxiety, tension or depression 3.4 5.2 16.2 -4.0 -1.6 -1.6 -2.5 -3.6 -1.4 -1.2 0.6 -1.7
Hair/balding pattern: Pattern 4 0.2 0.4 1.9 0.2 0.1 0.6 0.5 0.3 -0.6 1.0 1.4 -0.1
Birth weight of first child 2.9 5.2 13.1 2.6 1.8 1.5 2.5 2.0 2.5 1.5 -1.8 3.6
Peak expiratory flow (PEF) 0.4 0.9 2.9 1.7 0.5 0.4 0.1 1.7 0.7 1.0 0.6 0.1
Pulse wave reflection index 0.7 0.9 2.2 -1.2 -1.2 0.5 -1.2 -0.9 0.2 -0.4 1.5 -0.0
Ever highly irritable/argumentative for 2 days 2.8 3.3 13.4 -3.4 -0.2 -1.5 -0.6 -3.7 -0.8 -0.7 -0.8 -1.0
Loud music exposure frequency 0.6 0.7 1.8 -1.3 -0.5 -0.2 -0.6 -1.4 -1.1 -0.4 -0.7 -0.1
Qualifications: O levels/GCSEs or equivalent 1.7 2.7 6.5 1.3 -1.4 1.2 1.8 0.7 2.5 2.5 -1.5 -0.2
Mouth/teeth dental problems: Bleeding gums 0.8 1.1 3.1 -1.0 -1.8 -0.4 -0.6 -1.2 -0.4 0.1 -1.3 -1.4
Blood clot in the leg (DVT) 0.7 0.8 1.8 -0.9 0.7 -1.0 -0.9 -1.1 -1.4 -1.1 -0.2 0.4
Medication: Paracetamol 1.0 1.6 2.9 -1.6 -0.9 -0.9 -1.3 -1.7 -1.1 -1.2 0.8 -1.6
Headache pain in last month 0.5 0.8 1.8 -1.1 -0.3 -0.9 -0.8 -1.2 -0.3 -1.3 -0.5 -1.0
Medication for cholesterol, blood pressure or diabetes 0.6 0.9 2.2 0.9 0.3 1.2 0.0 1.2 1.5 1.3 0.1 0.9
Glaucoma (self-reported) 0.8 0.9 2.3 1.0 0.0 0.1 1.5 1.0 1.3 0.8 1.1 -0.9
Gout (self-reported) 1.3 1.8 4.5 -1.6 0.7 -0.9 -1.3 -1.4 -2.1 -1.2 1.4 -0.8
Hypothyroidism/myxoedema (self-reported) 1.1 2.2 6.6 1.7 -0.5 0.5 2.3 1.0 1.7 0.3 -2.6 0.9
Medication: Amlodipine 1.2 1.7 3.5 1.1 -0.7 -1.5 -0.6 1.6 -1.4 -0.4 1.9 -1.7
Medication: Ventolin 100micrograms inhaler 1.1 1.4 4.4 -0.5 0.7 -2.1 -0.2 -0.4 -1.7 -2.0 0.1 -0.2
Birth weight 0.5 1.2 3.6 1.9 0.3 0.5 0.4 1.4 0.6 0.7 1.9 0.3
Chronic bronchitis/emphysema (mother) 0.9 1.0 1.7 -1.3 -0.9 -1.0 -0.3 -1.0 -1.1 -0.6 -1.3 -1.1
High blood pressure (siblings) 0.8 1.2 3.8 -0.4 -0.8 1.8 -0.3 -0.4 1.4 -0.2 0.7 2.0
Forced vital capacity (FVC), Best measure 0.6 2.4 8.9 0.7 -1.9 3.0 0.5 0.5 2.1 1.0 0.3 1.6
Body fat percentage 0.5 2.0 6.4 -1.3 0.6 -2.5 0.4 -1.8 -1.1 -1.9 -0.2 -0.9
Leg fat percentage (right) 0.5 1.8 6.1 -0.6 1.2 -2.5 -0.2 -1.1 -1.5 -2.0 0.5 -0.8
Arm fat-free mass (right) 0.1 0.4 1.6 -0.7 -0.6 0.3 0.0 -1.3 0.8 0.3 -0.2 0.0
Exposure to tobacco smoke outside home 1.8 2.4 5.9 -1.2 0.4 -2.3 -1.1 -1.4 -2.4 -1.7 -1.1 -1.3
Comparative body size at age 10 0.2 0.5 3.3 0.6 -0.2 0.7 0.0 0.3 0.4 -0.3 1.8 -0.5
Number of full brothers 0.2 0.2 0.7 -0.4 -0.3 0.5 0.2 -0.9 0.2 -0.4 -0.4 0.4
Worry too long after embarrassment 2.4 4.0 11.0 -3.3 -1.4 -2.0 -2.1 -2.4 -0.5 -1.8 -0.1 -2.3
Seen a psychiatrist for nerves, anxiety, tension or depression 1.1 1.4 5.9 -2.4 -0.1 -0.7 -0.3 -1.9 -1.1 -0.7 -0.7 0.5
Wheeze or whistling in the chest in last year 1.1 1.9 4.0 -1.2 1.4 -1.3 -1.6 -1.2 -2.0 -1.1 1.7 0.1
Number of children fathered 0.3 0.3 1.7 -0.1 1.3 0.3 -0.4 -0.3 -0.3 -0.1 0.4 0.9
Reason for reducing amount of alcohol drunk: Health precaution 1.5 1.8 4.3 2.0 0.8 0.7 1.5 2.1 1.5 1.0 -1.1 0.1
Age at first live birth 0.8 1.3 4.7 1.0 -1.0 2.2 0.1 1.2 1.2 1.6 0.1 0.3
Pulse wave peak to peak time 3.0 3.5 9.5 1.0 1.9 2.7 0.8 0.9 1.3 2.5 0.8 3.1
Health satisfaction 0.3 0.4 2.2 0.2 -0.0 0.6 0.4 0.3 0.1 -0.2 0.7 1.5
Shortness of breath walking on level ground 2.6 3.1 7.3 -1.7 0.0 -2.6 -1.4 -1.9 -1.7 -2.7 -0.1 -1.6
Qualifications: College or University degree 3.2 10.1 23.4 3.2 0.5 4.1 2.7 3.0 4.3 4.8 -1.2 2.1
Eye problems/disorders: None of the above 0.6 0.7 4.1 -1.0 2.0 -0.3 0.6 -0.8 -0.4 -0.1 0.0 0.6
Mouth/teeth dental problems: Loose teeth 1.6 1.9 5.2 -0.2 0.4 1.8 1.7 -0.4 0.9 2.3 -1.8 0.9
Emphysema/chronic bronchitis 0.4 0.5 1.2 -0.7 0.2 0.6 0.9 -0.9 0.3 0.4 -1.1 0.7
Medication for pain relief, constipation, heartburn 1.5 2.5 4.6 1.3 0.1 1.9 1.6 1.2 1.9 1.9 -0.9 2.2
Neck or shoulder pain in last month 1.5 2.1 5.8 -1.7 -0.9 -1.7 -0.1 -2.4 -1.1 -1.6 -0.8 -1.2
Medication: Blood pressure 1.4 2.4 6.3 -1.3 0.4 -2.0 -0.6 -1.9 -2.5 -2.1 0.5 -0.7
Angina (self-reported) 0.8 1.1 5.7 0.0 0.6 0.1 1.0 -0.2 0.4 2.4 -1.1 -1.3
Migraine (self-reported) 1.9 2.4 5.0 -1.2 0.2 1.6 0.7 -1.8 2.2 1.5 -2.1 1.4
Medication: Ibuprofen 1.0 1.2 5.7 -0.6 -1.0 -1.3 -0.3 -0.9 -0.7 -0.8 0.4 -2.4
Medication: Allopurinol 1.3 1.7 3.3 -1.2 0.7 -1.3 -1.2 -0.9 -1.8 -1.7 1.6 -0.5
Medication: Omeprazole 0.8 0.9 2.7 0.3 1.1 -0.2 -0.7 0.3 -1.6 -1.4 1.0 0.8
Medication: Seretide 50 evohaler 1.3 1.5 3.9 -2.0 -1.1 -0.8 -0.8 -1.9 -0.5 -1.5 0.2 -1.1
Mean time to correctly identify matches 1.8 3.4 12.9 -0.6 1.8 -2.8 -1.7 -0.2 -3.6 -1.1 1.3 -0.5
Heart disease (mother) 0.4 0.5 1.0 0.2 -0.8 0.9 -0.8 0.3 -0.2 1.0 0.9 1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.3 0.8 0.8 0.9 -0.1 0.7 0.5 0.5 0.2 0.3 0.3
Whole body fat mass 0.3 1.4 3.6 -1.4 0.3 -1.9 0.2 -1.9 -0.8 -1.6 0.1 -0.7
Leg fat mass (right) 0.2 0.9 2.9 -0.7 0.8 -1.7 0.2 -1.3 -0.7 -1.3 0.4 -0.4
Arm predicted mass (right) 0.1 0.5 2.2 -0.9 -0.8 0.1 -0.1 -1.5 0.7 -0.0 -0.4 -0.2
Pulse rate, automated reading 0.7 2.3 6.3 2.5 0.9 0.6 1.8 1.4 2.0 0.3 -1.0 1.7
Alcohol intake frequency. 0.5 1.1 4.5 -1.2 -1.4 -0.4 -0.9 -2.1 -0.6 -0.4 -0.6 -0.7
Comparative height size at age 10 0.3 1.7 3.4 -1.2 -0.7 -1.3 1.9 -1.8 0.7 0.3 -1.8 -1.2
Number of full sisters 1.3 1.6 4.4 0.2 -0.0 -1.9 -1.1 0.3 -1.6 -2.1 -1.6 -0.3
Suffer from ‘nerves’ 0.5 0.8 2.3 -0.9 -0.3 -1.5 -0.4 -0.8 -0.8 -1.5 0.3 -0.8
Overall health rating 1.0 2.2 4.1 -1.6 -1.4 -1.6 -1.2 -2.0 -1.7 -1.8 -0.8 -0.3
Chest pain or discomfort 1.3 1.8 5.4 -1.6 -0.7 -1.6 -0.3 -2.3 -1.4 -1.0 -0.4 -1.5
Had major operations 1.1 1.2 3.5 -1.6 -0.7 0.2 -1.2 -1.4 -1.0 -1.9 0.1 -0.5
Age at last live birth 0.7 1.0 1.8 1.3 -0.1 0.4 1.3 1.3 1.0 0.8 -0.9 -1.0
Family relationship satisfaction 0.5 0.7 2.6 -0.9 0.3 -0.5 -1.2 -0.4 -0.8 -0.1 1.6 0.3
Leg pain on walking 1.2 1.6 5.7 -0.9 -0.0 -1.4 1.1 -0.8 -0.6 -0.7 -1.6 -2.4
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.4 2.2 -0.6 0.2 -1.5 -0.0 -0.7 -0.6 -0.5 -0.1 0.5
Commuting to job workplace: Car/motor vehicle 0.5 0.6 1.5 0.7 -0.9 1.2 0.1 0.6 1.1 0.7 -0.2 0.8
Illness, injury, bereavement, stress in last 2 years 2.1 2.5 5.5 1.2 -0.8 2.3 1.5 1.4 2.2 1.7 0.6 1.7
Medication: Aspirin 0.5 0.6 2.5 0.1 -0.3 -0.7 0.3 -0.3 -0.1 0.1 -1.5 -1.6
Supplements: Vitamin C 0.5 0.6 1.3 -1.0 -0.4 -0.5 -1.1 -1.1 -0.8 -0.4 0.7 -0.8
Knee pain experienced in last month 0.4 0.6 2.9 1.7 -0.6 -0.4 0.9 0.7 0.1 -0.4 -0.0 0.6
Hypertension (Self-reported) 0.8 2.3 5.6 -0.4 -0.8 -2.4 -1.5 -0.4 -2.2 -2.3 0.4 -1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.8 3.2 11.9 -0.1 -0.4 3.1 0.3 -0.5 2.5 0.8 0.2 3.4
Illnesses of father: Heart disease 0.4 0.6 2.0 0.7 1.1 0.3 -1.4 0.9 0.1 -0.3 0.2 0.6
Illnesses of siblings: Diabetes 1.2 1.5 4.1 -2.0 -1.8 -0.3 -0.9 -1.8 -0.3 -0.7 -1.1 -0.5
Smoking status: Previous 2.0 2.9 7.4 -1.8 0.2 -0.8 -2.5 -1.4 -2.2 -1.6 2.7 -0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.8 1.7 5.2 -2.3 -1.1 -0.6 -1.1 -2.1 -1.3 -0.9 -0.7 -0.3
Whole body fat-free mass 0.1 0.5 1.1 -0.4 -0.9 0.8 0.3 -1.0 1.1 0.3 0.3 -0.2
Leg fat-free mass (right) 0.1 0.7 2.7 -0.3 -1.0 1.0 0.8 -1.0 1.6 0.4 0.1 0.3
Arm fat percentage (left) 0.2 0.7 2.5 -0.3 0.3 -1.6 0.7 -0.9 -0.5 -1.3 0.2 -0.3
Average weekly red wine intake 0.3 0.4 1.0 0.3 -0.5 0.5 -0.9 1.0 0.0 -0.2 0.8 -0.6
Handedness (chirality/laterality): Left-handed 0.6 0.8 2.9 -0.0 -1.2 -0.7 0.3 0.4 -0.0 0.3 -1.7 -1.2
Mood swings 2.5 4.6 9.3 -3.0 -0.1 -1.1 -3.1 -2.5 -2.3 -2.1 2.2 -0.8
Loneliness, isolation 1.3 1.8 2.7 -1.3 -1.5 -1.5 -1.6 -1.1 -1.4 -1.6 0.8 -0.9
Long-standing illness, disability or infirmity 0.7 1.0 2.5 -0.6 -0.8 -1.3 -0.1 -1.2 -0.9 -1.1 -1.6 -0.7
Ever had bowel cancer screening 1.3 1.5 3.4 1.4 -0.1 1.4 1.1 0.9 1.9 1.2 -1.4 -0.7
Diabetes diagnosed by doctor 1.9 3.1 7.9 -1.0 -1.4 -2.1 -2.7 -0.7 -2.8 -1.6 0.1 -1.5
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 1.3 -0.7 0.1 0.2 -0.5 -0.8 1.1 -0.1 -1.1 -0.2
Friendships satisfaction 0.8 1.0 3.1 -0.7 0.7 0.8 -1.4 0.1 -0.6 0.9 1.8 0.9
Qualifications: nursing, teaching 1.1 1.8 4.4 1.1 -1.8 1.8 -0.2 0.8 1.6 2.1 0.7 -0.4
Commuting to job workplace: Walk 0.5 0.5 2.5 -1.6 -0.2 -0.2 0.3 -1.1 -0.3 -0.4 -0.5 -0.7
Eye problems/disorders: Cataract 0.5 0.6 2.3 1.5 -0.7 0.5 0.1 1.1 0.6 -0.1 -0.4 0.6
Mouth/teeth dental problems: Mouth ulcers 1.3 2.0 6.5 0.5 0.1 1.8 1.3 0.3 2.5 0.6 -1.7 1.9
Medication for cholesterol 0.6 0.9 2.4 1.5 0.9 0.6 1.1 1.5 0.5 0.6 0.6 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 0.5 0.2 -0.7 -0.2 -0.2 0.4 -0.7 -0.4 -0.6 -0.6
Back pain experienced in last month 0.5 0.7 2.0 -0.7 -1.3 -0.4 0.8 -0.9 0.2 -0.2 -1.4 -0.7
Mineral and other dietary supplements 0.5 0.7 1.9 -0.8 0.4 0.9 -1.4 -0.6 0.5 -0.5 0.7 1.0
Breast cancer (self-reported) 1.6 1.9 5.0 -0.6 -0.4 2.2 0.7 -1.0 1.5 1.5 0.8 2.2
Asthma (self-reported) 0.4 0.7 2.5 -1.5 0.0 -0.5 -0.7 -1.6 -0.5 0.3 0.7 -0.2
Osteoporosis (self-reported) 1.1 1.4 3.6 0.7 -1.1 1.4 0.2 1.1 1.9 1.0 -1.6 0.8
Osteoarthritis (self-reported) 0.9 1.1 4.3 1.8 -0.2 0.5 2.1 1.2 0.6 0.7 0.0 0.1
Medication: Aspirin 0.6 0.8 2.5 0.5 -0.3 -0.6 1.0 0.1 0.4 0.5 -1.6 -1.6
Medication: Gliclazide 2.1 2.3 8.3 0.6 1.9 -2.9 0.0 1.0 -2.5 -1.0 -0.2 -0.4
Illnesses of father: None of the above (group 1) 1.3 1.6 4.1 0.9 -1.7 0.0 1.9 0.9 1.2 0.7 -0.7 -2.0
Smoking status: Current 2.4 3.7 8.3 -2.0 0.7 -2.9 -1.3 -1.6 -2.4 -2.3 -1.2 -2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 3.0 1.3 -0.3 1.1 0.2 1.7 1.0 0.5 0.4 0.9
Whole body water mass 0.1 0.5 1.3 -0.4 -1.0 0.9 0.3 -1.1 1.1 0.3 0.4 -0.0
Leg predicted mass (right) 0.1 0.7 2.6 -0.2 -0.9 0.9 0.8 -0.9 1.6 0.3 0.2 0.3
Arm fat mass (left) 0.2 0.6 2.0 -0.8 -0.0 -1.2 0.4 -1.4 -0.2 -1.1 0.3 -0.3
Number of self-reported non-cancer illnesses 1.2 2.0 5.8 -2.1 -0.7 -1.4 -1.2 -2.4 -1.2 -1.1 -0.7 -1.0
Average weekly champagne plus white wine intake 3.5 4.8 9.3 1.3 1.9 2.5 2.4 1.4 3.0 1.9 -1.2 3.0
Miserableness 2.7 4.7 12.5 -3.5 0.3 -1.9 -2.6 -3.0 -1.5 -2.8 0.5 -0.5
Guilty feelings 1.4 2.1 4.9 -2.2 -0.0 -1.4 -1.2 -2.0 -1.8 -1.8 0.4 -0.2
Wears glasses or contact lenses 1.3 1.4 5.8 -0.7 -2.4 0.3 -0.9 -0.9 1.2 -0.7 -0.8 -1.5
Ever taken oral contraceptive pill 0.7 0.8 2.9 -0.3 -0.1 -1.4 -0.6 -0.1 -1.7 -0.6 -0.9 -0.6
Hearing aid user 0.9 1.0 4.5 -2.1 0.4 -0.1 0.1 -1.9 0.3 -0.2 -0.5 0.8
Mother’s age at death 1.9 2.4 6.2 1.4 2.5 1.4 0.8 1.5 0.3 1.1 1.6 2.1
Financial situation satisfaction 1.1 1.3 4.7 -2.2 -1.3 0.6 -1.1 -1.7 0.1 -0.0 0.1 -1.1
Tinnitus: Yes, now most or all of the time 0.6 0.7 2.8 0.9 -0.2 0.5 0.5 0.9 0.3 0.8 -1.0 -1.7
Commuting to job workplace: Public transport 0.9 1.1 4.4 -0.0 2.1 -0.6 -0.7 -0.2 -0.9 -0.0 1.6 0.8
Eye problems/disorders: Glaucoma 0.6 0.7 2.2 -0.1 -0.4 1.3 0.6 -0.0 1.5 0.7 1.3 0.3
Medication: Blood pressure 0.6 1.1 2.7 -0.4 -0.0 -1.1 -1.6 -0.4 -1.4 -1.5 0.9 0.6
Pain type(s) experienced in last month: Hip pain 1.7 2.1 6.3 -0.9 -0.2 -1.6 -0.4 -1.0 -2.1 -2.5 0.9 -1.7
Supplements: Fish oil (including cod liver oil) 0.8 1.0 2.8 0.3 -0.7 -1.5 0.3 -0.2 -1.3 -1.0 0.8 -1.7
High cholesterol (Self-reported) 0.5 1.0 2.8 -1.2 -1.4 -0.4 -0.5 -0.9 -0.0 0.4 -1.7 -1.0
Medication: Bendroflumethiazide 0.4 0.6 3.3 0.2 -0.6 -0.9 0.2 -0.2 0.0 -1.8 -0.2 0.9
Medication: Paracetamol 1.0 1.6 3.5 -1.5 -1.6 -0.3 -1.2 -1.9 -0.6 -1.0 0.7 -1.7
Medication: Lisinopril 1.9 2.5 6.3 -1.1 0.4 -1.8 -1.9 -1.3 -2.5 -2.4 0.8 -0.6
Medication: Atorvastatin 1.1 1.4 6.9 -1.1 -1.6 -0.2 -0.2 -0.6 0.3 1.0 -2.6 -0.6
Illnesses of father: High blood pressure 1.2 1.4 4.6 0.0 1.2 -0.1 -1.6 -0.4 -0.8 -1.1 1.6 2.1
Alcohol drinker status: Never 2.5 3.0 6.9 2.1 -0.8 0.7 1.7 1.9 2.6 2.2 -1.7 -0.9
Ever smoked 1.2 2.1 5.2 -1.1 -0.1 -0.8 -2.0 -0.5 -2.2 -1.5 2.3 -0.8
Basal metabolic rate 0.1 0.3 1.3 -0.5 -0.6 0.3 0.3 -1.1 0.8 0.0 0.3 -0.2
Leg fat percentage (left) 0.5 1.7 6.0 -0.8 1.1 -2.4 0.0 -1.2 -1.4 -1.8 0.4 -0.9
Arm fat-free mass (left) 0.1 0.6 1.8 -0.7 -0.6 0.9 0.2 -1.4 1.0 0.4 0.6 0.5
Number of operations (self-reported) 0.3 0.5 0.9 -0.7 0.1 0.4 -0.8 -0.8 -1.0 -0.9 0.0 -0.6
Average weekly beer plus cider intake 0.7 1.0 3.8 -0.3 0.2 -0.6 -1.0 -0.6 -1.2 -2.0 1.0 1.1
Irritability 4.8 8.0 19.5 -4.4 -1.4 -1.8 -3.2 -4.2 -2.2 -2.0 0.5 -3.3
Risk taking 1.4 2.0 6.9 -2.2 -0.4 -0.1 -0.6 -2.6 -0.1 0.8 -2.2 0.1
Ever had prostate specific antigen (PSA) test 2.8 3.2 7.4 -1.4 0.5 -2.7 -1.6 -1.2 -2.4 -2.5 0.4 -1.8
Fractured/broken bones in last 5 years 0.8 1.0 4.4 0.1 2.1 -0.4 1.0 0.4 -0.5 1.3 -1.0 -0.5
Age started oral contraceptive pill 1.7 2.1 4.5 0.8 -1.2 2.1 1.5 0.7 2.0 2.1 1.2 -0.3
Diastolic blood pressure, automated reading 0.7 2.0 6.0 0.9 0.3 2.4 1.4 0.6 0.7 1.3 1.1 2.4
Ever depressed for a whole week 0.3 0.4 0.9 -0.9 0.3 -1.0 -0.9 -0.4 0.0 -0.7 0.1 0.2
Unable to work because of sickness or disability 1.8 2.4 4.2 -2.1 -0.2 -1.5 -1.1 -2.0 -1.9 -1.3 -0.3 -1.9
Commuting to job workplace: Cycle 0.3 0.3 1.4 -0.2 -0.7 1.2 -0.1 0.2 0.7 0.5 0.5 -0.5
Myopia 0.2 0.2 0.9 -0.1 -0.2 -0.6 -0.7 0.1 -0.3 -0.4 -0.2 -0.9
Vascular/heart problems diagnosed by doctor 0.3 0.9 2.6 0.4 0.6 1.6 0.5 0.4 1.3 1.3 0.1 1.2
Cholesterol lowering medication 0.8 1.2 3.6 -0.7 0.1 -1.9 -1.1 -0.3 -1.1 -1.1 -1.4 -0.7
Medication: Omeprazole (e.g. Zanprol) 0.7 0.8 2.3 0.7 0.5 0.5 -0.5 0.7 -1.0 -0.9 1.5 1.2
Pain experienced in last month 1.0 1.7 3.8 1.1 0.8 1.9 0.1 1.5 1.1 1.9 0.7 1.6
Supplements: Calcium 0.9 1.0 5.3 -0.0 -0.6 -1.3 0.7 -0.1 -0.5 -0.7 -2.3 -0.2
Basal cell carcinoma (self-reported) 1.2 1.4 5.8 -0.8 -2.4 -0.2 -0.6 -0.9 -0.2 -0.1 0.7 -2.0
Heart attack/myocardial infarction (self-reported) 0.7 0.9 3.6 -1.0 1.9 -0.0 -0.0 -0.9 -0.0 0.2 -1.4 -0.6
Deep venous thrombosis (DVT) (self-reported) 0.6 0.7 2.0 -0.9 0.3 -0.8 -0.8 -1.2 -1.4 -0.9 0.3 0.2
Heart disease (siblings) 1.2 1.5 5.1 -1.2 -0.0 -1.4 -0.7 -1.2 -0.8 -2.2 -1.1 -0.9
Alcohol drinker status: Previous 1.6 1.9 5.0 -0.3 -0.0 -1.6 -1.5 -0.7 -2.2 -1.9 1.2 -1.3
Pack years of smoking 2.2 3.3 7.7 -1.7 -2.3 -1.1 -1.7 -2.3 -1.5 -2.8 -0.4 -1.4
Impedance of whole body 0.3 1.7 4.0 -1.3 -0.0 -2.0 -0.8 -0.4 -1.9 -1.6 -1.0 -1.1
Leg fat mass (left) 0.2 0.9 2.7 -0.7 0.8 -1.6 0.4 -1.3 -0.6 -1.2 0.4 -0.5
Arm predicted mass (left) 0.1 0.5 1.4 -0.5 -0.7 0.8 0.3 -1.2 1.2 0.4 0.4 0.3