Best TWAS P=4.79e-14 · Best GWAS P=1.52e-39 conditioned to 4.59e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | NAP1L5 | 0.11 | 0.11 | lasso | 3 | 0.09 | 5.3e-08 | 5.23 | 5.1 | 2.9e-07 | 0.28 | 0.99 | 0.01 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | FAM13A | 0.12 | 0.00 | enet | 7 | 0.01 | 6.9e-02 | 0.38 | 6.1 | 9.1e-10 | 0.58 | 0.18 | 0.35 | TRUE |
| 3 | GTEx | Nerve Tibial | NAP1L5 | 0.12 | 0.06 | enet | 15 | 0.12 | 1.4e-08 | 2.70 | 7.5 | 5.2e-14 | 0.36 | 0.37 | 0.48 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | NAP1L5 | 0.09 | 0.05 | enet | 5 | 0.08 | 6.0e-07 | 5.23 | 5.3 | 1.5e-07 | 0.26 | 0.77 | 0.12 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | FAM13A | 0.06 | 0.00 | blup | 220 | 0.02 | 2.4e-03 | -2.26 | 7.5 | 4.8e-14 | 0.14 | 0.09 | 0.04 | TRUE |