TWAS hub - NAP1L5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1140	0.0410	1.9e-04	0.108	NA	0.087	NA	0.093	4.1e-09	NA	1.3e-07	NA	5.3e-08
2	GTEx	Adipose Visceral Omentum	0.2030	0.0710	6.6e-04	0.017	NA	0.032	NA	0.047	4.4e-02	NA	8.4e-03	NA	1.9e-03
3	GTEx	Artery Aorta	0.1160	0.0510	9.7e-03	0.020	NA	0.000	NA	0.002	2.8e-02	NA	3.2e-01	NA	2.3e-01
4	GTEx	Artery Tibial	0.1079	0.0423	2.1e-03	0.069	NA	0.047	NA	0.054	4.3e-06	NA	1.4e-04	NA	4.7e-05
5	GTEx	Esophagus Muscularis	0.0900	0.0460	6.9e-03	0.002	NA	-0.004	NA	-0.004	2.2e-01	NA	6.7e-01	NA	6.8e-01
6	GTEx	Heart Atrial Appendage	0.2290	0.0730	1.5e-03	0.008	NA	0.017	NA	0.025	1.3e-01	NA	5.4e-02	NA	2.5e-02
7	GTEx	Lung	0.1533	0.0529	1.3e-03	0.033	NA	0.053	NA	0.036	1.4e-03	NA	6.0e-05	NA	9.4e-04
8	GTEx	Nerve Tibial	0.1153	0.0520	7.5e-03	0.057	NA	0.116	NA	0.066	7.3e-05	NA	1.4e-08	NA	2.0e-05
9	GTEx	Skin Sun Exposed Lower leg	0.0880	0.0380	3.4e-03	0.051	NA	0.077	NA	0.062	4.4e-05	NA	6.0e-07	NA	7.7e-06
10	METSIM	Adipose	0.0372	0.0170	4.1e-03	0.000	0.011	0.000	0.013	0.004	3.1e-01	7.5e-03	2.6e-01	4.2e-03	8.1e-02
11	ROSMAP	Brain Pre-frontal Cortex	0.1165	0.0355	7.5e-05	0.031	0.043	0.030	0.042	0.031	7.1e-05	2.8e-06	9.1e-05	3.2e-06	5.6e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	6	7	8	9	10	11
Waist Hip Ratio (WHR)	4.5	20.2	56.7	5.1	4.4	4.8	4.6	4.8	3.5	7.5	5.3	1.4	3.4
Average weekly champagne plus white wine intake	4.3	5.9	10.5	-3.0	-2.7	-3.2	-3.2	-2.4	-2.0	-1.5	-3.0	-1.7	-2.0
Lung FEV1/FVC ratio	4.0	20.4	60.1	-4.3	-4.2	-4.6	-5.0	-0.6	-2.3	-3.9	-2.8	7.3	-7.8
Leg pain on walking	4.0	5.0	9.4	2.6	1.3	2.5	2.6	2.2	2.0	0.7	3.1	2.6	2.9
Risk taking	3.7	5.5	12.4	2.8	1.3	3.1	2.7	2.1	2.4	2.1	2.3	3.5	1.4
Type 2 Diabetes (T2D) (2018)	3.6	6.7	13.0	2.8	2.0	2.8	2.7	3.2	3.0	3.5	3.6	0.8	1.4
Hayfever/allergic rhinitis (self-reported)	3.5	4.7	9.7	-3.0	-1.6	-3.1	-3.1	-1.5	-1.7	-0.9	-2.8	-1.8	-2.1
Diabetes diagnosed by doctor	3.5	5.8	12.9	2.9	1.1	3.1	2.6	2.4	2.7	3.0	3.6	0.3	1.7
Mouth/teeth dental problems: Loose teeth	3.0	3.5	9.4	-2.3	0.0	-2.2	-1.9	-1.2	-1.7	-2.2	-2.4	-3.1	-1.1
Myopia	3.0	4.4	9.1	2.8	2.1	3.0	2.7	1.1	2.0	1.7	2.3	-0.3	2.4
Birth weight	2.8	6.2	11.5	-3.0	-2.2	-3.4	-3.2	-1.1	-2.3	-2.6	-2.8	0.2	-3.2
Medication: Atorvastatin	2.8	3.5	15.1	1.2	0.4	1.5	1.2	3.9	1.7	3.0	2.3	0.8	0.3
Bipolar Disorder (2011)	2.6	2.5	4.3	2.0	1.5	1.7	2.0	1.4	0.0	1.4	2.1	1.5	2.0
Medication: Metformin	2.6	3.7	7.2	2.1	-0.4	2.4	2.0	2.2	2.7	2.6	2.3	1.2	1.0
Reason for reducing amount of alcohol drunk: Health precaution	2.5	2.9	6.3	-2.5	-0.3	-2.2	-2.3	0.2	-0.8	-1.8	-2.0	-1.6	-2.3
Wears glasses or contact lenses	2.5	2.9	5.3	2.0	2.3	1.8	1.8	1.1	1.6	2.1	2.2	1.5	1.0
Vascular/heart problems diagnosed by doctor	2.3	6.2	11.2	-2.6	-1.3	-2.7	-3.1	-3.1	-2.5	-3.4	-3.3	-0.7	-2.1
Loud music exposure frequency	2.2	2.4	5.4	1.8	0.7	2.1	2.1	0.8	1.2	1.3	2.3	1.7	1.6
Shortness of breath walking on level ground	2.2	2.6	10.6	1.9	0.8	2.1	2.2	0.8	1.3	-0.3	1.0	-0.8	3.3
Medication for cholesterol	2.2	3.3	6.2	-1.8	-1.5	-2.0	-2.1	-2.3	-2.5	-2.2	-2.0	-1.3	-0.4
Guilty feelings	2.2	3.3	7.5	-2.3	-1.9	-2.4	-2.7	-1.2	-1.6	-1.9	-1.6	-0.6	-1.9
Diabetes (self-reported)	2.1	3.3	7.1	2.3	0.4	2.4	2.1	1.6	2.0	2.0	2.7	0.5	1.8
Gout (self-reported)	2.1	2.9	12.7	1.2	-1.0	1.7	1.7	0.2	0.7	3.6	-0.8	1.8	2.6
Ever had bowel cancer screening	2.1	2.4	4.9	1.9	1.1	2.2	1.8	1.1	1.4	1.4	2.0	1.4	1.5
Reaction Time	2.0	3.8	9.1	2.8	1.1	2.9	3.0	0.6	2.2	1.3	1.8	1.1	1.9
Bilateral oophorectomy (both ovaries removed)	2.0	2.3	4.6	1.6	1.0	1.5	1.6	2.1	1.8	2.0	1.6	1.2	1.3
Eye problems/disorders: Cataract	2.0	2.3	4.8	1.6	1.6	1.8	1.8	1.8	1.4	2.2	1.4	0.9	0.7
Number of full sisters	1.9	2.4	5.8	-1.3	-2.4	-1.5	-1.4	-1.5	-1.9	-1.1	-2.0	-1.7	0.3
Emphysema/chronic bronchitis	1.8	2.0	10.6	-0.7	-0.2	-1.4	-0.7	-0.8	-2.4	-0.6	-0.4	-3.3	1.3
High blood pressure	1.7	4.6	10.2	2.1	1.0	2.1	2.5	3.2	2.1	3.0	2.8	0.4	1.5
Exposure to tobacco smoke outside home	1.7	2.3	4.8	2.1	1.6	2.2	2.1	1.4	1.4	1.3	1.3	1.3	0.8
Hypertension (Self-reported)	1.7	4.6	9.2	2.3	0.9	2.2	2.6	2.8	1.8	2.9	3.0	0.1	2.0
Back pain experienced in last month	1.7	2.5	8.4	-0.2	0.5	-0.5	-0.5	-2.3	-2.0	-2.7	-1.2	-2.9	-0.2
Mother’s age at death	1.7	2.2	5.2	-1.9	-2.2	-1.4	-1.9	-1.2	-0.9	-1.2	-2.3	-0.9	-0.7
Taking other prescription medications	1.6	2.4	4.8	2.0	0.4	1.8	2.1	1.0	1.4	2.0	1.7	0.2	2.2
High blood pressure (mother)	1.6	2.3	8.4	0.7	0.4	1.1	1.3	2.9	2.2	2.3	1.5	-0.1	0.9
Pulse wave peak to peak time	1.6	1.9	3.8	-1.9	-2.0	-1.8	-1.6	1.9	-0.1	-0.3	-1.4	-0.1	-1.4
Ovarian Cancer	1.5	1.9	6.2	-1.7	-1.0	-1.4	-1.5	-0.8	-1.0	-0.8	-2.5	-1.3	-1.6
Chronotype (morning person)	1.5	3.5	8.8	2.4	2.2	2.5	3.0	0.2	2.4	1.1	2.2	0.3	1.4
Medication for hormone replacement therapy	1.5	1.7	5.9	1.6	2.4	1.4	1.5	-0.1	1.6	-0.1	0.9	1.4	0.7
Birth weight of first child	1.5	2.8	16.7	-1.2	-0.0	-1.4	-1.9	0.8	0.1	-0.1	-0.3	2.5	-4.1
Comparative body size at age 10	1.5	4.2	10.6	3.0	2.6	3.1	3.3	1.0	1.1	0.9	2.2	0.1	1.6
Osteoarthritis (self-reported)	1.5	2.0	5.4	-1.3	-0.4	-1.6	-1.3	-1.6	-2.2	-2.3	-1.3	-0.3	-1.1
Medication: Blood pressure	1.5	2.8	10.3	1.2	1.4	1.2	1.7	3.2	0.9	2.7	2.0	0.8	0.1
Major Depression (MDD)	1.4	1.7	4.1	2.0	0.6	1.8	2.0	-0.7	0.5	-0.0	1.6	0.0	2.0
Neuroticism	1.4	3.4	6.8	-2.5	-1.2	-2.5	-2.6	1.0	-1.9	-1.5	-1.7	-0.2	-2.6
Impedance of arm (right)	1.4	6.5	14.3	-3.2	-2.5	-3.3	-3.0	-2.5	-2.1	-3.8	-2.8	0.3	-1.6
Pulse wave Arterial Stiffness index	1.4	1.7	3.7	1.8	1.9	1.6	1.5	-1.9	-0.1	0.2	1.2	-0.2	1.1
Impedance of arm (left)	1.4	6.5	14.5	-3.2	-2.2	-3.2	-3.0	-2.8	-1.9	-3.8	-2.9	-0.0	-1.7
Wheeze or whistling in the chest in last year	1.4	2.4	5.8	2.3	0.7	2.0	1.8	0.9	0.9	1.7	1.7	-0.0	2.4
Medication: Allopurinol	1.4	1.9	7.5	0.8	-0.3	1.7	1.5	-0.0	0.8	2.7	-0.5	1.9	1.6
Medication: Gliclazide	1.3	1.4	3.8	1.2	0.8	1.6	1.3	1.1	1.2	1.9	1.7	0.4	-0.1
Impedance of whole body	1.3	6.6	11.9	-3.1	-2.5	-3.1	-2.9	-2.8	-2.1	-3.4	-3.3	-0.6	-1.5
Worry (Nagel 2018)	1.2	2.6	5.7	-2.2	-1.9	-2.1	-2.4	-0.1	-1.5	-0.9	-1.8	-0.1	-1.9
Maternal smoking around birth	1.2	1.8	6.4	1.8	0.7	1.5	1.8	0.8	0.6	0.2	1.4	1.0	2.5
Falls in the last year	1.2	1.6	3.1	1.8	1.1	1.5	1.7	-1.4	0.7	-1.0	1.5	1.3	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.5	5.4	-1.1	-1.0	-0.9	-1.0	-2.3	-1.1	-1.0	-1.5	-0.7	-1.1
Friendships satisfaction	1.2	1.5	4.2	-1.0	0.7	-0.9	-0.8	-0.3	-1.7	-1.9	-1.6	-2.1	-0.7
Neuroticism (Nagel 2018)	1.1	2.5	5.7	-2.2	-1.1	-2.2	-2.4	0.5	-1.8	-0.9	-1.7	-0.1	-2.0
Hayfever, allergic rhinitis or eczema	1.1	2.4	6.4	-2.5	-1.1	-2.5	-2.5	0.7	0.2	-0.3	-1.8	0.7	-1.6
Had other major operations	1.1	1.3	3.1	1.4	0.9	1.8	1.6	0.6	1.1	0.8	1.5	0.4	1.1
Length of working week for main job	1.1	1.3	3.2	1.6	0.9	1.8	1.5	-0.9	0.7	0.9	1.6	0.6	0.6
High blood pressure (siblings)	1.1	1.5	3.2	1.3	0.7	1.5	1.4	1.6	1.8	1.8	0.9	-0.1	1.0
Eye problems/disorders: None of the above	1.1	1.3	3.4	-1.4	-1.2	-1.8	-1.8	-1.1	-1.1	-0.7	-0.4	-0.4	-0.9
Mean time to correctly identify matches	1.1	2.2	5.3	2.1	0.2	2.2	2.3	0.4	1.5	1.5	1.2	0.9	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	3.7	-0.9	-1.9	-1.0	-1.0	-1.8	-1.5	-1.0	-0.3	-1.0	0.2
Medication: Lisinopril	1.1	1.4	2.9	1.3	1.1	1.7	1.3	1.1	1.6	1.0	1.0	-0.3	1.5
Crohns Disease (2017)	1.0	2.3	4.7	1.9	2.2	2.0	2.1	0.2	1.1	1.9	1.6	1.1	-0.0
Crohns Disease (2012)	1.0	1.7	3.3	1.6	1.8	1.7	1.8	0.7	0.6	1.2	1.7	1.2	-0.0
Fed-up feelings	1.0	1.7	5.4	-1.6	-1.0	-1.8	-1.7	0.1	-2.3	-1.5	-1.2	-0.5	-0.1
Alcohol intake versus 10 years previously	1.0	1.5	3.0	1.2	0.5	1.3	1.6	1.4	1.7	1.2	1.3	0.9	1.4
Worrier / anxious feelings	1.0	1.8	4.8	-2.2	-1.1	-1.9	-2.0	-1.1	-1.0	-1.3	-1.5	0.2	-0.7
Number of full brothers	1.0	1.3	3.1	-1.6	-0.8	-1.2	-1.5	-0.7	-0.4	-1.0	-1.8	-1.4	0.7
Had major operations	1.0	1.1	3.1	1.8	1.4	1.2	1.7	0.4	0.2	0.8	0.9	0.8	1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	6.1	0.8	2.5	0.9	0.6	0.4	0.4	-0.0	0.8	1.0	-1.2
Eye problems/disorders: Glaucoma	1.0	1.2	3.5	1.6	0.5	1.7	1.9	1.4	0.5	0.7	0.3	-0.5	0.9
Ever depressed for a whole week	1.0	1.3	3.5	1.6	1.9	1.2	1.5	0.8	0.8	0.7	0.9	0.4	1.3
Sensitivity / hurt feelings	0.9	1.6	2.9	-1.7	-1.3	-1.7	-1.5	0.4	-1.2	-1.3	-1.5	0.9	-1.1
Pack years adult smoking proportion	0.9	1.3	3.1	1.4	1.7	1.4	1.3	0.8	0.7	0.5	0.9	-1.2	1.8
Medication: Atenolol	0.9	1.1	3.6	0.8	1.7	0.5	0.8	0.9	0.2	1.9	1.4	-1.1	-0.4
Impedance of leg (left)	0.9	4.4	9.0	-2.7	-2.3	-2.8	-2.6	-1.8	-1.9	-1.9	-3.0	-0.5	-1.5
Nervous feelings	0.9	1.7	2.8	-1.5	-1.5	-1.5	-1.5	-0.7	-1.5	-1.5	-1.7	0.4	-1.2
Pain all over the body in last month	0.9	1.0	2.0	1.4	0.4	1.2	1.1	0.7	1.2	0.7	0.7	1.4	1.0
Lung cancer (father)	0.9	1.0	5.5	0.6	1.3	0.4	0.8	2.3	0.9	-0.0	1.1	0.9	0.4
Pulse wave reflection index	0.9	1.1	6.4	1.1	0.9	0.8	0.7	-2.5	-0.6	-0.6	0.2	-0.6	1.3
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	2.4	-1.5	-0.3	-1.2	-1.4	-0.7	-0.9	-1.5	-1.6	-0.6	-1.3
Glaucoma (self-reported)	0.9	1.1	2.6	1.5	1.4	1.6	1.5	1.2	0.6	0.8	0.2	-0.3	0.8
Pain type(s) experienced in last month: Hip pain	0.9	1.1	2.7	0.9	1.2	1.0	0.9	1.4	1.2	1.0	1.6	0.2	-0.8
Ulcerative Colitis	0.8	1.2	2.7	1.0	1.0	0.9	1.0	1.6	1.4	1.5	1.0	-1.0	0.7
Number of treatments/medications taken	0.8	1.4	3.0	1.4	-0.4	1.5	1.7	1.3	0.6	1.2	1.5	-0.2	1.5
Ever had hysterectomy (womb removed)	0.8	0.9	2.0	1.4	1.3	0.7	0.9	0.2	0.5	1.4	1.4	0.6	0.4
Waist circumference	0.8	2.8	8.0	1.9	2.8	2.0	1.8	0.5	1.6	0.5	2.7	0.8	1.2
Past tobacco smoking	0.8	1.4	5.4	-1.1	-1.4	-1.0	-1.1	-2.3	-0.4	-1.9	-0.9	-0.5	-0.3
Ever unenthusiastic/disinterested for a whole week	0.8	0.9	1.7	1.3	1.3	0.9	1.2	1.3	1.1	0.3	0.8	0.7	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	2.1	-1.2	-1.2	-1.1	-1.4	-0.8	-1.4	-1.3	-1.3	-0.8	-1.1
Headache pain in last month	0.8	1.4	5.6	1.3	0.9	1.4	1.5	1.0	0.5	-0.5	1.2	-0.6	2.4
Chronic bronchitis/emphysema (mother)	0.8	1.0	2.9	1.0	0.0	1.2	0.9	1.0	1.0	1.2	1.0	0.1	1.7
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	3.9	-0.4	0.0	-0.2	0.1	-1.9	-1.2	-0.4	-0.7	-2.0	-1.1
Handedness (chirality/laterality): Left-handed	0.8	0.9	4.7	0.8	2.2	1.0	1.2	0.4	0.9	-0.2	1.0	0.5	0.2
Illnesses of father: None of the above (group 1)	0.8	1.0	2.3	-1.4	-0.4	-1.5	-1.5	-0.1	-0.6	-0.4	-1.4	-0.7	-1.2
Basal cell carcinoma (self-reported)	0.8	1.0	5.2	0.8	0.8	1.1	0.7	-1.3	0.6	0.5	0.6	2.3	-0.3
Pack years of smoking	0.8	1.2	2.7	1.3	1.5	1.3	1.3	1.0	0.7	0.4	0.9	-0.9	1.7
Irritable Bowel Disease (IBD)	0.7	1.6	3.8	1.5	1.3	1.4	1.6	0.6	1.6	2.0	1.4	-0.0	0.4
Mean Putamen Volume	0.7	0.8	3.1	-0.2	0.6	-0.2	-0.4	1.3	0.9	1.3	0.3	1.8	-0.6
Rheumatoid Arthritis	0.7	0.9	4.5	-0.0	0.4	0.0	0.2	-1.6	-1.4	-2.1	-0.0	-0.6	-0.6
Triglycerides	0.7	1.2	2.9	1.7	0.7	1.4	1.2	-0.4	0.3	1.4	1.5	-1.0	1.1
Cardiovascular Disease	0.7	2.3	6.7	1.2	0.4	1.3	1.7	1.1	1.4	1.9	2.0	-1.3	2.6
Diabetes (mother)	0.7	0.9	3.8	-1.3	0.2	-1.2	-1.2	0.8	0.2	-0.1	-1.9	-0.6	-0.2
Trunk fat percentage	0.7	2.9	19.0	-1.2	-0.3	-0.9	-0.9	-3.0	-0.9	-4.4	-0.2	0.1	0.6
Qualifications: CSEs or equivalent	0.7	0.9	4.5	-0.4	-0.3	-0.0	-0.3	-2.1	-0.7	-0.2	-0.7	-1.9	-0.0
Body fat percentage	0.7	2.9	18.7	-1.2	-0.3	-1.0	-1.0	-3.0	-0.9	-4.3	-0.2	0.3	0.4
Number of children fathered	0.7	0.8	1.9	1.1	-0.5	1.0	1.1	0.3	0.9	0.7	1.4	1.2	0.9
Knee pain experienced in last month	0.7	1.0	5.2	-0.1	1.8	-0.3	0.0	-1.0	-1.2	-2.3	0.2	0.5	0.4
Breast cancer (self-reported)	0.7	0.8	1.4	1.1	1.0	1.1	1.0	0.2	1.1	0.4	1.2	1.1	1.0
Ever taken oral contraceptive pill	0.7	0.8	3.1	0.1	0.4	0.3	0.2	1.8	1.2	1.3	1.4	0.6	0.6
Irritability	0.7	1.3	4.1	-2.0	-1.1	-1.4	-1.7	1.1	-0.2	-0.9	-1.1	0.6	-0.1
Unable to work because of sickness or disability	0.7	0.9	2.5	-0.7	-0.8	-0.9	-0.6	-1.6	-1.0	-0.5	-1.1	-1.6	-0.5
Smoking Status	0.6	1.4	3.4	1.7	0.7	1.6	1.5	0.7	-0.5	1.5	0.8	-0.9	1.9
Average weekly spirits intake	0.6	0.8	2.2	1.5	0.7	1.1	1.2	0.4	0.2	-0.3	1.0	0.5	1.3
Ever used hormone-replacement therapy (HRT)	0.6	0.8	7.0	0.2	-0.2	-0.2	-0.2	1.2	0.0	-0.0	0.4	2.6	-0.5
Vitamin and mineral supplements	0.6	0.8	2.1	0.5	1.0	1.2	0.8	-0.3	1.5	1.1	-0.4	-0.4	1.4
Impedance of leg (right)	0.6	2.7	5.8	-2.2	-1.8	-2.4	-2.2	-1.1	-1.4	-1.4	-2.4	-0.2	-0.8
Average weekly fortified wine intake	0.6	0.7	3.1	-0.4	-0.9	-0.1	-0.4	-1.8	-0.7	0.0	-0.3	-1.3	-0.8
Serious illness, injury or assault to yourself	0.6	0.7	1.8	1.2	1.0	1.0	1.1	-0.4	0.5	-0.1	0.7	0.3	1.3
Multivitamins +/- minerals	0.6	0.8	2.8	-0.5	-1.2	-1.2	-0.8	0.5	-1.0	-0.6	0.5	0.7	-1.7
Chronic bronchitis/emphysema (father)	0.6	0.7	4.0	0.6	0.9	0.7	0.8	-0.5	0.0	0.3	0.3	-1.0	2.0
Heart attack	0.6	0.7	2.8	0.5	-0.1	0.5	0.9	0.9	0.7	0.7	1.3	0.6	1.7
Medication: Simvastatin	0.6	0.9	4.4	0.6	0.2	0.9	1.0	-0.2	0.4	0.6	0.1	-1.5	2.1
Illnesses of siblings	0.6	0.8	2.1	-0.8	-0.1	-0.8	-0.8	-1.4	-1.2	-1.1	-0.7	0.5	-1.1
Neuroticism score	0.6	1.3	3.0	-1.6	-0.8	-1.5	-1.7	0.5	-1.1	-1.0	-1.0	0.7	-1.4
Mouth/teeth dental problems: Dentures	0.6	1.0	4.0	0.9	0.4	0.8	0.9	-0.1	0.9	0.9	2.0	0.7	1.5
Breastfed as a baby	0.6	0.8	2.2	1.5	0.4	1.3	1.2	-0.3	-0.6	1.0	0.8	0.5	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	2.6	-0.8	-0.0	-0.8	-0.6	1.6	0.4	-0.3	-0.9	-1.2	-1.1
Neck or shoulder pain in last month	0.6	0.9	3.5	0.5	1.9	0.6	0.5	1.9	0.4	0.1	0.1	0.6	-1.2
Medication: Omeprazole	0.6	0.7	1.8	1.3	0.9	1.3	1.3	0.1	-0.5	0.4	0.8	-0.1	1.1
Alcohol intake frequency.	0.6	1.4	2.7	1.4	1.1	1.3	1.6	0.3	1.4	0.8	1.3	1.6	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	2.9	1.4	1.7	1.4	1.4	-0.4	1.4	0.7	1.1	0.5	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.6	-0.6	-0.9	-0.4	-0.5	-1.2	-0.8	-0.3	-1.2	-1.3	-1.0
Mineral and other dietary supplements	0.6	0.8	1.9	1.0	1.4	1.3	1.2	-0.5	1.0	0.4	0.4	0.7	0.6
Tinnitus: Yes, now most or all of the time	0.6	0.6	3.8	-0.2	-0.4	-0.1	-0.4	1.9	0.9	0.6	0.9	0.3	-0.9
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.5	-0.9	-0.8	-1.0	-0.9	0.2	-1.6	-0.8	-0.4	-1.4	-0.8
Pain experienced in last month	0.6	1.1	5.1	-1.3	-2.3	-1.2	-1.1	0.2	-0.4	1.0	-0.6	-0.0	-0.6
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.7	0.6	0.1	0.6	0.9	0.8	0.8	0.8	1.4	0.6	1.6
Alcohol drinker status: Previous	0.6	0.7	1.9	1.1	1.3	1.3	1.4	-0.3	0.3	-0.0	0.5	0.8	0.8
Alzheimer’s Disease (in father)	0.5	0.5	2.4	-0.1	1.6	-0.3	-0.0	0.4	-0.1	-0.9	0.4	0.0	-1.5
Age at First Birth	0.5	0.7	2.0	-0.1	0.2	-0.2	-0.5	1.4	0.7	1.3	-0.3	1.0	-1.3
Body Mass Index (BMI) (2010)	0.5	0.7	4.5	-0.1	-0.8	-0.2	-1.0	-1.1	-0.8	-2.1	0.3	0.2	0.4
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.0	0.0	-0.1	-0.0	-0.0	1.4	-0.4	1.4	0.4	-1.1	-1.0
Blood White Count	0.5	3.5	8.5	1.8	1.7	2.1	2.3	0.9	0.5	1.8	1.8	-2.4	2.9
Supplements: Zinc	0.5	0.5	1.8	0.2	-0.4	0.1	0.2	-1.2	-1.1	-1.3	-0.5	-0.3	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	4.5	0.7	0.3	0.8	0.7	0.9	0.3	0.3	0.9	2.1	-0.1
Stomach or abdominal pain in last month	0.5	0.6	2.5	-0.6	-0.5	-0.9	-0.6	0.2	-1.6	-1.2	-0.5	0.3	-1.1
Hearing difficulty/problems with background noise	0.5	0.8	3.0	0.0	0.9	0.2	0.1	1.7	1.0	1.4	1.3	0.2	-0.6
Hair/balding pattern: Pattern 2	0.5	0.6	2.2	-0.1	1.5	-0.2	0.4	1.0	-0.1	0.9	-0.6	0.9	-1.0
Had menopause	0.5	0.7	3.7	0.9	1.1	0.8	0.3	0.1	-0.5	-0.5	0.6	1.9	-0.1
Financial difficulties in last 2 years	0.5	0.6	2.5	1.1	0.3	0.9	0.7	0.1	-0.6	-0.3	1.2	1.6	0.3
Arm fat percentage (right)	0.5	1.8	12.6	-0.6	0.4	-0.3	-0.4	-2.3	-0.5	-3.6	0.5	0.8	0.4
Trunk fat-free mass	0.5	3.0	7.2	2.0	2.7	1.9	1.8	1.6	1.5	2.0	2.2	0.4	-0.9
Hair/balding pattern: Pattern 3	0.5	0.8	2.0	1.2	0.6	1.2	1.3	-0.0	0.2	0.8	1.1	-0.0	1.4
Noisy workplace	0.5	0.6	3.2	0.3	-0.0	0.3	0.5	-0.0	0.9	0.9	0.8	1.8	0.9
Medication: Cholesterol lowering	0.5	0.7	2.6	0.9	-0.8	0.6	0.8	0.7	0.1	0.2	1.0	-1.1	1.6
Depression (self-reported)	0.5	0.6	2.9	-0.5	-1.7	-0.9	-0.9	0.4	0.0	-0.3	-0.7	0.2	-0.9
Trunk predicted mass	0.5	3.1	7.5	2.0	2.7	1.9	1.8	1.7	1.5	2.0	2.3	0.5	-0.8
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	3.6	-1.1	0.8	-0.9	-1.0	-0.2	-0.1	-0.5	-0.9	0.7	-1.9
Arm fat-free mass (right)	0.5	2.3	5.5	2.0	2.4	1.8	1.8	1.0	1.3	1.6	2.1	-0.1	-0.3
Worry too long after embarrassment	0.5	0.8	1.7	-1.2	-0.9	-1.1	-1.2	0.6	-0.6	-0.3	-1.1	0.4	-1.3
Heart disease (mother)	0.5	0.6	1.6	0.6	0.9	0.4	0.7	0.8	0.5	1.3	1.1	0.8	0.5
Illnesses of father: Heart disease	0.5	0.7	2.5	0.6	-0.9	0.5	0.3	-1.6	-1.5	-0.9	0.4	0.5	-0.1
Arm fat percentage (left)	0.5	1.9	13.8	-0.7	0.6	-0.4	-0.5	-2.4	-0.3	-3.7	0.5	0.7	0.3
Long-standing illness, disability or infirmity	0.5	0.8	2.2	0.2	1.3	0.4	0.4	1.3	1.4	1.5	0.9	0.3	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	1.9	-1.1	-1.4	-1.2	-1.0	0.7	-0.2	0.9	-0.3	1.4	-1.4
Financial situation satisfaction	0.5	0.6	1.7	0.4	1.1	0.5	0.5	1.3	0.2	0.6	0.6	1.2	-0.8
Medication: Bendroflumethiazide	0.5	0.8	2.9	0.6	-0.2	0.9	0.9	1.7	0.5	0.7	1.0	0.2	1.3
Alcohol drinker status: Never	0.5	0.6	1.0	-0.9	-0.8	-1.0	-0.9	-1.0	-0.7	-0.7	-0.8	0.3	-0.8
Ever smoked	0.5	0.8	3.3	0.8	0.6	0.8	0.8	1.6	0.2	1.8	0.4	0.4	0.3
Arm predicted mass (left)	0.5	2.7	6.1	2.0	2.5	2.0	2.0	1.3	1.4	1.6	2.3	0.4	-0.2
Bipolar Disorder (2018)	0.4	0.7	2.9	0.9	0.6	0.7	1.1	0.7	0.3	0.4	0.7	-0.1	1.7
Depressed Affect (Nagel 2018)	0.4	0.7	1.8	-1.1	-0.1	-1.3	-1.3	0.7	-1.3	-0.5	-0.6	-0.0	-0.8
Ulcerative Colitis (UC)	0.4	0.8	2.1	0.7	0.2	0.3	0.8	1.1	1.4	1.4	0.9	-1.0	0.5
Breast Cancer	0.4	0.9	2.5	-0.5	-0.7	-0.6	-0.2	1.2	1.6	1.3	-1.0	0.3	1.3
Coronary Artery Disease (CAD)	0.4	0.5	1.0	0.5	-0.3	0.5	1.0	0.6	-0.1	1.0	0.7	0.8	1.0
Fasting Glucose	0.4	0.4	2.0	0.1	0.5	-0.1	0.0	0.1	0.7	-0.6	0.1	1.3	-1.4
Lupus	0.4	0.6	3.6	0.9	1.9	0.8	0.9	0.3	-0.1	-0.1	0.9	-0.2	0.1
Neuroticism (2016)	0.4	0.5	3.8	-0.0	0.0	-0.0	-0.4	-0.4	-0.9	-0.6	0.7	0.4	-1.9
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.3	-0.6	-0.2	-0.7	-0.7	-0.4	-1.5	-0.9	-1.0	0.8	-0.9
Hearing difficulty/problems: Yes	0.4	0.6	3.1	0.3	0.2	-0.0	0.0	1.2	0.2	-0.2	1.8	1.4	-0.4
Angina	0.4	0.5	1.5	-1.1	-0.2	-1.1	-0.8	-0.3	0.4	0.3	-0.5	-1.2	0.5
Diabetes (father)	0.4	0.5	1.2	0.9	0.0	0.8	0.7	0.6	0.5	1.0	1.1	0.7	0.4
Leg fat-free mass (left)	0.4	1.9	5.3	1.7	2.3	1.7	1.7	-0.0	1.3	-0.0	2.2	0.4	0.2
Current tobacco smoking	0.4	0.6	2.9	0.7	-0.3	0.3	0.4	0.3	-1.1	-0.1	0.4	-1.1	1.7
Trunk fat mass	0.4	1.7	12.4	-0.5	0.5	-0.4	-0.4	-2.3	-0.4	-3.5	0.4	0.2	0.3
Alcohol usually taken with meals	0.4	0.6	4.6	0.5	0.9	0.1	0.2	-2.1	0.1	-0.4	0.6	0.4	-0.8
Allergy	0.4	0.9	2.9	1.5	-0.1	1.7	1.6	-0.2	-0.2	0.6	1.2	-0.2	0.5
Hip circumference	0.4	1.9	12.7	-1.3	0.2	-0.9	-0.9	-1.8	-0.5	-3.6	-0.5	-0.3	-0.8
Illnesses of mother	0.4	0.5	1.9	0.4	-0.4	-0.0	-0.0	-1.4	-1.2	-1.0	0.1	-0.0	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	7.2	-1.3	-0.2	-1.2	-1.3	0.6	-0.1	0.2	-1.0	0.6	-2.7
Exposure to tobacco smoke at home	0.4	0.5	1.8	0.7	1.1	0.6	0.6	-0.4	-0.1	0.1	0.1	1.3	0.9
Tense / ‘highly strung’	0.4	0.7	1.9	-1.1	-1.0	-1.0	-1.2	0.4	-0.7	0.3	-0.8	-0.0	-1.4
Blood clot in the leg (DVT)	0.4	0.5	1.9	0.5	0.6	0.8	0.6	0.3	1.4	1.2	0.3	0.6	-0.4
Medication: Paracetamol	0.4	0.7	2.9	-0.8	-0.2	-0.8	-0.7	-0.8	-0.9	-1.7	-0.4	-1.0	0.2
Leg fat percentage (right)	0.4	1.3	8.1	-0.3	0.4	-0.1	-0.2	-1.7	-0.1	-2.9	0.8	0.9	1.2
Health satisfaction	0.4	0.5	1.4	0.7	0.1	1.2	1.1	-0.4	0.5	-0.9	0.1	0.5	0.8
Medication for pain relief, constipation, heartburn	0.4	0.6	1.7	-0.8	-1.0	-1.1	-1.0	-0.1	-0.3	-0.3	-1.3	0.5	-1.0
Medication: Ibuprofen	0.4	0.5	1.3	-0.9	0.3	-0.8	-0.7	-0.7	-0.5	-0.1	-1.1	-0.8	-0.6
Arm predicted mass (right)	0.4	1.8	4.0	1.7	2.0	1.5	1.6	0.9	1.2	1.5	1.9	0.1	-0.4
Age at last live birth	0.4	0.7	5.1	-0.2	0.2	-0.2	-0.1	2.2	0.9	0.3	1.0	0.2	-0.3
Supplements: Vitamin C	0.4	0.5	1.5	1.1	1.2	0.6	1.0	0.1	0.2	-0.0	0.9	-0.0	0.3
Smoking status: Previous	0.4	0.5	1.5	0.8	0.7	0.8	0.8	1.2	0.1	1.2	0.5	0.6	-0.0
Whole body fat-free mass	0.4	2.3	6.4	1.9	2.5	1.8	1.8	0.9	1.3	1.2	2.2	0.4	-0.6
Loneliness, isolation	0.4	0.6	1.4	-1.1	-0.6	-0.9	-1.0	-0.0	-0.8	-0.6	-1.2	-0.7	0.1
Qualifications: nursing, teaching	0.4	0.6	1.4	1.0	1.0	1.0	1.1	-0.0	0.8	0.8	0.2	-0.4	1.2
Smoking status: Current	0.4	0.6	2.4	0.6	-0.1	0.3	0.4	0.7	-1.0	0.0	0.2	-1.5	1.6
Whole body water mass	0.4	2.2	5.7	1.9	2.4	1.8	1.7	0.9	1.3	1.2	2.1	0.4	-0.5
Hearing aid user	0.4	0.4	1.3	-0.5	-0.9	-0.6	-0.5	-1.0	-1.1	-0.4	0.4	0.6	-0.0
Commuting to job workplace: Public transport	0.4	0.5	2.1	-0.2	0.6	0.1	-0.3	-0.8	-0.5	-1.4	0.2	-0.5	-1.5
High cholesterol (Self-reported)	0.4	0.7	3.2	-0.5	-1.0	-0.4	-0.2	0.1	-0.3	0.7	-0.4	-1.6	1.8
Illnesses of father: High blood pressure	0.4	0.5	1.6	-0.1	-0.2	0.5	0.2	0.3	1.3	1.1	0.5	1.1	-0.7
Leg fat percentage (left)	0.4	1.4	9.3	-0.5	0.3	-0.2	-0.4	-2.1	-0.3	-3.0	0.5	0.8	0.8
Arm fat-free mass (left)	0.4	2.3	4.8	2.0	2.2	1.9	2.0	1.0	1.2	1.4	2.1	0.4	-0.2
Fractured/broken bones in last 5 years	0.4	0.5	1.8	0.7	0.8	0.6	0.3	0.7	0.7	0.7	0.7	1.3	0.0
Age started oral contraceptive pill	0.4	0.5	3.7	-0.2	-0.2	-0.1	0.1	0.3	1.0	-0.6	-0.2	1.9	-0.4
Cholesterol lowering medication	0.4	0.7	3.3	-0.2	-0.2	0.5	0.3	1.1	1.3	1.8	-0.1	-0.8	0.2
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.5	0.6	0.0	0.5	0.6	-0.8	-1.2	-0.5	0.3	-0.5	1.2
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	2.3	0.5	0.3	0.7	0.5	0.1	1.5	1.3	0.3	0.8	-0.2
Heart disease (siblings)	0.4	0.4	0.8	0.4	-0.8	0.8	0.3	0.8	0.8	0.8	0.6	0.9	0.5
Intelligence (Savage-Jansen 2018)	0.3	0.8	2.4	-0.7	-1.6	-1.2	-0.9	1.0	-0.9	-0.8	-0.2	-0.4	-1.3
Alzheimer’s Disease (in mother)	0.3	0.3	0.9	0.1	0.4	0.3	0.0	-1.0	-0.6	-0.5	-0.7	-0.9	0.5
Alzheimer’s Disease (including proxy)	0.3	0.5	2.7	0.8	1.6	0.8	0.8	-0.1	-0.0	-0.2	0.6	-0.4	0.1
HbA1C	0.3	0.4	1.2	-1.1	-0.7	-0.9	-0.4	0.2	0.3	0.1	-0.7	0.7	-0.4
Blood Eosinophil Count	0.3	2.4	6.9	0.9	-1.2	1.1	1.6	2.4	1.4	2.2	0.2	-1.0	2.6
Blood Red Count	0.3	2.7	9.4	1.4	1.0	1.7	2.0	-0.0	1.1	2.6	0.5	-3.1	1.6
Heel T-Score	0.3	2.3	12.7	1.6	1.8	1.5	1.5	0.1	0.2	-0.5	0.9	3.6	0.8
BMI	0.3	1.7	5.5	0.8	0.9	1.2	1.2	-0.3	1.3	-1.0	2.3	1.5	1.9
Systolic Blood Pressure	0.3	1.3	6.2	0.3	0.3	0.5	0.2	1.6	-0.0	2.5	1.3	-1.2	-1.2
Lung FVC	0.3	1.6	12.0	-0.5	0.8	-0.1	-0.2	0.4	-0.1	1.9	-1.0	-3.5	0.1
Medication: Co-codamol	0.3	0.3	0.9	-0.5	0.5	-0.3	-0.1	-0.3	-0.8	-0.9	-1.0	-0.6	0.4
Severe depression (siblings)	0.3	0.3	2.3	-0.2	-0.6	-0.4	-0.2	-0.0	-0.5	-0.1	-0.7	-1.5	0.1
Hand grip strength (right)	0.3	0.7	1.4	1.2	1.0	0.9	1.0	1.2	0.8	1.0	0.7	-0.3	0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	2.1	0.4	1.4	0.7	0.3	0.1	0.5	0.0	-0.0	0.7	0.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.0	0.7	-0.2	0.8	0.6	-0.7	0.5	1.0	0.5	-0.0	0.6
Medication: Levothyroxine sodium	0.3	0.4	1.3	0.4	1.1	0.6	0.9	0.8	0.3	0.8	0.0	-0.8	0.1
Body mass index (BMI)	0.3	1.3	2.7	0.9	1.6	1.2	1.1	-0.8	0.7	-1.6	1.7	0.8	1.4
Leg predicted mass (left)	0.3	1.8	4.8	1.7	2.2	1.7	1.7	0.1	1.3	0.0	2.2	0.5	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	2.1	-0.5	0.3	-0.7	-0.6	-0.1	-1.1	-1.3	-0.9	1.4	-0.4
Fluid intelligence score	0.3	0.6	2.3	0.8	0.5	0.4	0.5	1.5	0.6	0.5	1.4	0.5	-0.2
Father’s age at death	0.3	0.5	2.3	-0.4	1.5	-0.3	-0.5	0.7	0.1	0.2	-0.9	-0.1	-1.1
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	6.6	-1.0	0.2	-0.9	-0.9	0.8	0.4	0.9	-0.6	0.5	-2.6
Pulse rate	0.3	0.5	2.5	-0.3	-0.3	-0.5	-0.3	-0.7	-1.6	-1.2	-0.2	0.7	-0.5
Happiness	0.3	0.4	1.6	-0.2	1.2	-0.1	-0.1	0.5	0.6	0.4	-0.6	0.2	-1.3
Qualifications: A levels/AS levels or equivalent	0.3	0.7	4.0	-0.3	1.0	0.1	-0.1	0.8	1.2	-0.0	-0.2	0.9	-2.0
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	2.1	0.0	0.5	-0.0	0.1	-0.2	-0.3	0.1	-0.4	1.5	-0.9
Arm fat mass (right)	0.3	1.1	7.8	-0.3	0.9	-0.0	-0.2	-1.5	-0.1	-2.8	0.6	0.6	-0.0
Hair/balding pattern: Pattern 4	0.3	0.6	1.5	-1.2	-1.2	-1.1	-1.0	0.2	0.3	0.3	0.2	-0.3	-1.2
Peak expiratory flow (PEF)	0.3	0.8	2.9	-0.5	-0.4	-0.6	-0.6	0.6	0.3	1.2	0.4	1.7	-1.5
Ever highly irritable/argumentative for 2 days	0.3	0.3	2.7	-0.2	-0.1	-0.0	-0.2	0.6	-0.3	-0.3	-0.2	-1.6	0.6
Age at first live birth	0.3	0.6	1.5	-1.1	-0.2	-1.1	-1.2	1.2	0.1	-0.2	-0.1	-0.3	-0.9
Medication: Blood pressure	0.3	0.6	2.9	0.7	-0.4	0.7	0.8	-0.3	-0.2	0.1	0.7	-1.0	1.7
Medication: Seretide 50 evohaler	0.3	0.3	1.3	0.7	-0.1	0.2	0.4	0.1	0.1	-0.0	0.9	-0.5	1.1
Whole body fat mass	0.3	1.5	10.7	-0.4	0.7	-0.2	-0.3	-2.0	-0.1	-3.3	0.6	0.3	0.2
Leg fat mass (right)	0.3	1.2	7.0	0.2	0.8	0.3	0.2	-1.6	0.2	-2.6	1.2	0.7	0.9
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.8	0.6	-0.2	0.4	0.5	-1.2	0.0	-0.3	0.3	0.3	1.3
Medication: Aspirin	0.3	0.4	1.2	0.4	0.1	0.9	0.8	0.6	0.5	0.4	0.7	-0.5	1.1
Leg fat-free mass (right)	0.3	1.6	4.4	1.6	2.1	1.6	1.6	-0.1	1.0	-0.0	1.9	0.2	-0.2
Average weekly red wine intake	0.3	0.4	1.5	0.5	1.2	0.3	0.2	-0.4	-0.2	-1.0	0.4	0.2	-1.2
Leg predicted mass (right)	0.3	1.5	4.2	1.6	2.0	1.6	1.6	-0.3	0.9	-0.1	1.9	0.2	-0.2
Arm fat mass (left)	0.3	1.1	7.7	-0.2	1.0	-0.0	-0.1	-1.5	-0.0	-2.8	0.7	0.6	-0.1
Number of self-reported non-cancer illnesses	0.3	0.5	2.1	0.5	0.0	0.3	0.8	0.9	0.7	1.1	0.4	-0.2	1.5
Medication: Paracetamol	0.3	0.5	2.1	-0.9	-0.6	-0.7	-0.7	-0.2	-0.5	-1.4	-0.5	-0.3	-0.0
Basal metabolic rate	0.3	1.7	5.7	1.6	2.4	1.6	1.6	0.3	1.1	0.4	2.0	0.4	-0.4
Average weekly beer plus cider intake	0.3	0.4	1.2	-0.3	-0.8	-0.1	-0.8	1.1	0.7	1.1	0.1	-0.6	0.1
Diastolic blood pressure, automated reading	0.3	1.1	2.0	1.4	1.2	1.3	1.2	-1.4	-0.9	0.1	1.2	-0.4	0.9
Leg fat mass (left)	0.3	1.2	7.7	0.1	0.7	0.2	0.1	-1.9	0.1	-2.8	1.0	0.7	0.7
Depression (Nagel 2018)	0.2	0.4	1.9	0.0	-0.1	0.0	0.1	0.4	-1.1	-0.1	-0.2	1.4	-0.8
Schizophrenia (2018)	0.2	0.5	1.8	-0.4	-1.3	-0.4	-0.3	-0.5	-0.6	-0.9	-1.2	-0.7	0.1
HDL Cholesterol	0.2	0.3	0.7	-0.7	-0.0	-0.7	-0.5	0.3	-0.6	-0.5	-0.6	0.6	-0.8
LDL Cholesterol	0.2	0.3	2.0	-0.1	0.0	-0.2	-0.2	-0.2	-0.1	0.6	-0.5	-0.4	-1.4
Allergy or Eczema	0.2	0.5	1.6	-1.2	-0.4	-1.2	-1.2	0.4	-0.1	-0.2	-0.9	-0.0	-0.1
Respiratory disease	0.2	0.5	2.0	0.6	1.1	0.1	0.6	0.7	-0.6	-0.4	0.1	0.6	1.4
Hand grip strength (left)	0.2	0.5	1.2	1.1	0.9	0.7	0.8	0.4	0.1	0.7	0.8	-0.5	0.5
Relative age of first facial hair	0.2	0.4	1.2	-0.6	-0.8	-0.5	-0.6	0.1	0.6	-0.1	-1.0	1.1	-0.7
Systolic blood pressure, automated reading	0.2	0.6	2.7	0.8	0.4	0.5	0.3	0.1	-1.0	1.1	1.6	-0.8	-0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.9	-0.4	-0.0	-0.2	-0.2	-0.4	-0.1	-0.9	-0.6	-0.0	-0.9
Relative age voice broke	0.2	0.3	1.3	-0.5	-1.1	-0.5	-0.8	-0.3	-0.2	0.1	-0.4	0.4	-0.3
Age when periods started (menarche)	0.2	0.6	1.4	-0.7	0.6	-1.1	-0.7	0.3	-0.4	-0.5	-1.0	1.0	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	3.3	-0.1	0.7	-0.2	-0.2	-0.0	-0.3	-0.6	-0.2	1.8	-0.3
Supplements: Glucosamine	0.2	0.3	0.8	-0.3	-0.7	-0.6	-0.7	0.9	0.4	0.6	0.5	0.3	-0.3
Forced vital capacity (FVC)	0.2	0.8	3.0	-0.4	1.0	-0.1	-0.1	0.8	0.8	1.7	-0.3	-1.7	-1.1
Qualifications: None of the above	0.2	0.5	1.4	0.7	0.3	0.6	0.5	0.6	1.1	0.5	0.7	0.6	1.2
Mouth/teeth dental problems	0.2	0.4	1.0	0.8	-0.8	0.6	0.6	0.6	0.6	1.0	0.0	0.6	0.3
Weight	0.2	1.2	4.2	0.9	2.1	1.1	1.0	-0.9	0.7	-1.4	1.6	0.6	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.2	1.4	0.3	0.5	0.4	0.3	1.2	0.1	-0.7	0.1	0.5	0.2
Number of live births	0.2	0.3	1.2	0.2	-0.0	0.1	-0.2	0.6	0.7	0.9	1.1	0.5	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.8	-0.5	0.7	-0.2	-0.3	-0.1	0.1	0.5	-0.7	-0.9	0.0
Prospective memory result	0.2	0.2	0.9	0.2	-0.1	0.2	-0.0	-1.0	0.6	0.1	0.6	0.6	-0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.8	0.6	0.6	0.7	0.9	0.4	0.3	0.7	0.4	-0.5	0.4
Medication: Amlodipine	0.2	0.2	0.8	-0.2	0.7	0.2	0.5	0.8	-0.2	-0.0	-0.3	-0.9	0.2
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.0	0.6	0.3	0.5	0.3	0.4	-0.5	0.1	0.8	-0.0	1.0
Forced vital capacity (FVC), Best measure	0.2	0.6	2.1	-0.1	1.1	-0.0	0.0	0.9	0.8	1.4	-0.0	-1.2	-1.0
Angina (self-reported)	0.2	0.3	1.2	-0.7	0.0	-0.7	-0.4	-0.1	0.6	0.5	-0.2	-1.1	0.7
Migraine (self-reported)	0.2	0.2	1.1	-0.1	-1.1	0.4	-0.1	0.2	0.7	0.5	-0.5	0.4	0.3
Pulse rate, automated reading	0.2	0.8	3.3	0.6	0.4	0.2	0.4	-0.3	-1.1	-1.8	0.7	-1.4	0.8
Comparative height size at age 10	0.2	0.9	6.0	0.0	1.5	-0.5	-0.3	0.0	-0.7	0.0	0.5	-0.5	-2.5
Overall health rating	0.2	0.4	1.0	-1.0	-0.7	-1.0	-1.0	-0.3	-0.1	-0.2	-0.6	-0.6	-0.2
Chest pain or discomfort	0.2	0.3	1.7	0.5	0.6	0.1	0.8	0.3	-0.4	-0.4	-0.1	-0.2	1.3
Family relationship satisfaction	0.2	0.3	1.2	0.2	0.4	0.5	0.3	-0.2	-0.7	0.3	-1.1	-0.9	-0.0
Illnesses of siblings: Diabetes	0.2	0.3	0.9	0.4	0.6	0.5	0.5	-0.0	0.1	0.5	0.1	-0.8	0.9
Commuting to job workplace: Walk	0.2	0.2	0.7	0.0	-0.0	0.4	-0.1	0.6	0.8	0.1	0.4	0.3	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	1.1	0.1	1.0	0.5	0.3	-1.0	-0.3	-1.1	0.1	-0.9	-0.2
Miserableness	0.2	0.3	1.6	0.2	0.9	0.0	-0.1	0.6	0.0	0.0	0.2	1.3	-0.5
Number of operations (self-reported)	0.2	0.3	0.8	0.4	0.9	0.5	0.5	-0.9	-0.3	-0.9	0.1	-0.1	0.4
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.7	0.6	0.4	0.3	0.4	0.0	-0.3	-0.4	0.8	0.8	0.6
Commuting to job workplace: Cycle	0.2	0.2	0.6	-0.5	-0.7	-0.5	-0.4	0.6	0.0	0.3	-0.8	0.6	-0.2
Supplements: Calcium	0.2	0.2	0.8	-0.3	-0.9	-0.2	-0.2	0.5	0.1	0.6	-0.1	-0.2	0.9
Bipolar Disorder or Schizophrenia	0.1	0.3	1.3	0.3	-0.6	0.2	0.4	0.0	-0.2	-0.2	-0.5	-0.6	1.2
Schizophrenia vs Biploar Disorder	0.1	0.2	0.5	-0.5	-0.7	-0.2	-0.2	-0.4	0.1	0.3	-0.7	-0.0	-0.4
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.7	-0.0	-0.8	-0.4	-0.0	1.3	0.0	-0.3	0.4	0.5	0.1
Prostate Cancer	0.1	0.2	0.6	-0.2	-0.7	-0.6	-0.6	0.3	0.0	-0.3	-0.0	0.6	0.1
Primary Biliary Cirrhosis	0.1	0.1	0.6	-0.1	0.1	-0.0	-0.1	-0.5	0.2	0.0	0.6	0.8	-0.3
Schizophrenia (2014)	0.1	0.3	1.2	-0.4	-0.8	-0.7	-0.3	-0.2	-0.6	-0.4	-1.1	-0.3	0.0
Blood Platelet Count	0.1	0.7	2.1	-1.2	-0.6	-1.3	-0.9	0.1	-0.2	-1.5	-0.4	-0.6	0.6
Height	0.1	2.3	13.3	0.7	1.9	0.4	0.3	1.6	1.6	1.4	0.4	0.9	-3.6
Hypothyroidism (self reported)	0.1	0.2	1.5	-0.4	0.4	-0.0	0.0	0.1	0.2	-0.1	-0.1	-1.2	0.2
Hair Pigment	0.1	1.7	8.0	1.3	0.3	1.2	1.2	0.7	0.8	1.9	2.8	1.0	0.8
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.5	0.3	-0.1	0.5	0.4	-0.7	-0.7	-0.3	0.3	0.5	-0.2
Townsend deprivation index at recruitment	0.1	0.1	0.6	0.2	-0.8	0.0	0.1	-0.6	0.2	-0.1	-0.0	-0.3	-0.1
Sitting height	0.1	0.5	2.7	0.4	0.8	0.2	0.5	0.6	1.1	0.5	0.3	-0.1	-1.6
Number of incorrect matches in round	0.1	0.1	0.3	-0.4	0.0	-0.4	-0.4	0.1	0.2	0.1	-0.4	-0.5	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.9	0.4	0.9	0.2	0.2	0.5	-0.2	-0.1	0.1	0.2	-0.6
Medication: Ramipril	0.1	0.1	0.6	0.0	-0.3	0.0	0.4	0.4	-0.8	-0.2	-0.2	-0.4	-0.5
Time employed in main current job	0.1	0.1	0.4	-0.3	-0.2	0.2	-0.2	-0.3	0.6	0.3	0.1	-0.5	0.5
Asthma	0.1	0.3	1.5	-0.1	0.1	-0.5	-0.3	0.1	0.2	-1.0	-0.3	1.2	0.3
Medication: Lansoprazole	0.1	0.1	0.4	-0.3	-0.1	-0.3	-0.1	-0.4	0.4	-0.6	0.2	-0.1	-0.4
Standing height	0.1	0.9	6.9	0.4	1.7	0.2	0.3	0.2	0.3	0.3	0.4	-0.2	-2.6
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.4	-0.4	-0.5	-0.1	-0.2	-0.6	0.1	0.2	0.0	0.5	-0.4
Qualifications: College or University degree	0.1	0.4	2.1	-0.0	0.4	-0.1	-0.2	0.9	0.9	0.4	0.2	0.7	-1.5
Suffer from ‘nerves’	0.1	0.2	0.7	-0.1	-0.3	-0.1	-0.3	-0.4	-0.9	-0.5	0.3	0.9	-0.5
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.6	-0.2	-0.4	-0.2	0.1	-0.2	0.2	-0.6	-0.8	-0.4	0.3
Mood swings	0.1	0.1	0.4	-0.4	-0.2	-0.2	-0.7	-0.1	-0.2	0.4	0.1	0.4	-0.6
Asthma (self-reported)	0.1	0.2	1.6	0.2	0.3	-0.2	-0.1	0.1	0.1	-0.8	-0.2	1.3	0.5
Osteoporosis (self-reported)	0.1	0.2	0.4	-0.2	-0.6	-0.6	-0.6	0.2	-0.5	0.2	-0.5	-0.5	0.1
Medication: Aspirin	0.1	0.2	0.8	0.0	-0.2	0.3	0.4	0.2	0.2	0.0	0.3	-0.9	0.9
Tanning	0.0	0.2	1.3	0.2	-0.2	0.2	0.2	-0.4	-0.1	-0.4	-0.0	-0.2	1.1

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