Best TWAS P=2.58e-17 · Best GWAS P=8.79e-24 conditioned to 0.008
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | 7.7 | 6.9 | 7.2e-12 | -0.39 | 0.84 | 0.05 | FALSE |
| 2 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | 7.5 | -7.8 | 8.8e-15 | 0.60 | 0.32 | 0.11 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | -8.4 | 8.5 | 2.6e-17 | -0.85 | 0.12 | 0.82 | TRUE |