[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr1:25,475,418-27,210,721

Best TWAS P=1.17e-11 · Best GWAS P=2.08e-08 conditioned to 0.0203

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adrenal Gland	MTFR1L	0.22	0.09	enet	16	0.10	1.9e-04	-3.9	-5.6	2.2e-08	0.69	0.22	0.74	FALSE
2	GTEx	Brain Cerebellum	SEPN1	0.36	0.23	lasso	12	0.26	3.3e-08	-4.3	-5.3	9.3e-08	0.62	0.23	0.70	FALSE
3	GTEx	Breast Mammary Tissue	MTFR1L	0.12	0.07	enet	14	0.04	3.0e-03	-5.3	6.2	5.3e-10	-0.88	0.03	0.95	FALSE
4	GTEx	Cells Transformed fibroblasts	RP1-125I3.2	0.06	0.04	enet	19	0.03	3.3e-03	-3.9	6.8	1.2e-11	-0.54	0.06	0.58	TRUE
5	GTEx	Colon Transverse	RP1-317E23.7	0.23	0.29	enet	15	0.32	1.0e-15	-5.3	5.3	1.4e-07	-0.96	0.02	0.98	FALSE
6	GTEx	Esophagus Gastroesophageal Junction	MTFR1L	0.09	0.13	lasso	3	0.11	1.2e-04	-5.4	5.2	2.1e-07	-0.90	0.03	0.93	FALSE
7	GTEx	Esophagus Mucosa	MTFR1L	0.25	0.17	enet	16	0.15	3.3e-10	-5.5	5.7	9.6e-09	-0.98	0.01	0.99	FALSE
8	GTEx	Esophagus Mucosa	RP1-317E23.7	0.21	0.20	enet	11	0.17	3.3e-11	-5.5	5.1	3.1e-07	-0.94	0.02	0.98	FALSE
9	GTEx	Heart Atrial Appendage	MTFR1L	0.20	0.28	enet	15	0.24	4.3e-11	-5.6	5.2	2.2e-07	-0.95	0.01	0.99	FALSE
10	GTEx	Heart Atrial Appendage	RP1-317E23.7	0.23	0.31	enet	15	0.25	1.6e-11	-5.6	5.4	6.3e-08	-0.96	0.01	0.99	FALSE
11	GTEx	Heart Left Ventricle	MTFR1L	0.41	0.37	enet	16	0.39	6.9e-22	-5.5	5.5	3.5e-08	-0.98	0.01	0.99	FALSE
12	GTEx	Heart Left Ventricle	RP1-317E23.7	0.32	0.29	enet	13	0.29	7.8e-16	-5.5	5.6	2.5e-08	-0.98	0.01	0.99	FALSE
13	GTEx	Muscle Skeletal	MTFR1L	0.25	0.28	lasso	9	0.31	1.3e-30	-5.5	5.4	6.6e-08	-0.98	0.01	0.99	FALSE
14	GTEx	Muscle Skeletal	RP1-317E23.7	0.22	0.22	lasso	10	0.26	3.9e-25	-5.5	5.2	2.5e-07	-0.96	0.01	0.99	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	CNKSR1	0.15	0.10	lasso	7	0.09	1.0e-05	-4.6	5.2	2.3e-07	-0.10	0.49	0.47	FALSE
16	GTEx	Skin Sun Exposed Lower leg	MTFR1L	0.12	0.05	enet	24	0.05	3.8e-05	-5.6	5.6	1.8e-08	-0.79	0.02	0.98	FALSE
17	GTEx	Stomach	MTFR1L	0.14	0.00	enet	17	0.01	1.5e-01	-3.2	5.5	3.6e-08	-0.30	0.06	0.24	FALSE
18	GTEx	Thyroid	MTFR1L	0.28	0.21	enet	19	0.23	1.3e-17	-5.5	5.3	1.0e-07	-0.98	0.01	0.98	FALSE
19	GTEx	Thyroid	RP1-317E23.7	0.23	0.25	lasso	4	0.22	1.0e-16	-5.5	5.4	7.8e-08	-0.98	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC646471	0.09	0.12	lasso	4	0.11	1.0e-06	-5.6	5.6	2.7e-08	-0.98	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Esophageal Carcinoma	LOC646471	0.13	0.09	enet	6	0.11	2.2e-04	-5.5	5.6	1.8e-08	-0.90	0.01	0.97	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LOC646471	0.10	0.11	blup	60	0.10	1.6e-11	-5.6	5.5	2.8e-08	-0.96	0.00	1.00	FALSE
23	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LOC646471	0.11	0.10	enet	5	0.09	7.4e-06	-5.6	5.5	2.9e-08	-0.99	0.00	0.99	FALSE
24	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	LOC646471	0.06	0.07	lasso	2	0.07	5.2e-04	-5.5	5.7	1.5e-08	-0.98	0.01	0.96	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	PAQR7	0.02	0.02	blup	58	0.01	2.1e-02	-5.6	5.8	7.9e-09	-0.93	0.02	0.84	FALSE
26	The Cancer Genome Atlas	Stomach Adenocarcinoma	LOC646471	0.12	0.14	blup	60	0.14	2.7e-10	-5.6	5.8	7.3e-09	-0.95	0.00	1.00	FALSE