TWAS hub - MTFR1L

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adrenal Gland	0.223	0.0722	3.0e-05	0.088	NA	0.100	NA	0.096	4.6e-04	NA	1.9e-04	NA	2.6e-04
2	GTEx	Artery Aorta	0.104	0.0470	3.2e-03	0.076	NA	0.051	NA	0.060	5.7e-05	NA	8.4e-04	NA	3.0e-04
3	GTEx	Artery Tibial	0.142	0.0429	1.4e-06	0.129	NA	0.101	NA	0.123	2.6e-10	NA	2.5e-08	NA	7.8e-10
4	GTEx	Breast Mammary Tissue	0.117	0.0480	3.7e-04	0.075	NA	0.043	NA	0.016	1.1e-04	NA	3.0e-03	NA	5.1e-02
5	GTEx	Breast Mammary Tissue (Male)	0.113	0.0662	4.3e-02	-0.003	NA	-0.006	NA	-0.013	3.7e-01	NA	4.6e-01	NA	9.4e-01
6	GTEx	Breast Mammary Tissue (Female)	0.106	0.0698	6.8e-02	-0.010	NA	0.006	NA	0.006	9.8e-01	NA	2.0e-01	NA	2.1e-01
7	GTEx	Cells EBV-transformed lymphocytes	0.132	0.0620	9.1e-03	0.149	NA	0.113	NA	0.149	1.5e-05	NA	1.6e-04	NA	1.4e-05
8	GTEx	Colon Transverse	0.210	0.0520	1.1e-09	0.294	NA	0.271	NA	0.267	2.0e-14	NA	2.8e-13	NA	4.8e-13
9	GTEx	Esophagus Gastroesophageal Junction	0.093	0.0430	5.0e-03	0.133	NA	0.094	NA	0.106	1.6e-05	NA	2.8e-04	NA	1.2e-04
10	GTEx	Esophagus Mucosa	0.253	0.0750	1.1e-09	0.167	NA	0.150	NA	0.049	2.6e-11	NA	3.3e-10	NA	3.2e-04
11	GTEx	Esophagus Muscularis	0.237	0.0610	7.1e-10	0.203	NA	0.198	NA	0.143	1.9e-12	NA	3.7e-12	NA	4.9e-09
12	GTEx	Heart Atrial Appendage	0.205	0.0590	1.6e-07	0.279	NA	0.239	NA	0.048	5.7e-13	NA	4.3e-11	NA	3.4e-03
13	GTEx	Heart Left Ventricle	0.410	0.0746	5.6e-17	0.370	NA	0.388	NA	-0.002	1.1e-20	NA	6.9e-22	NA	4.3e-01
14	GTEx	Muscle Skeletal	0.251	0.0482	0.0e+00	0.284	NA	0.303	NA	0.307	5.4e-28	NA	3.5e-30	NA	1.3e-30
15	GTEx	Skin Sun Exposed Lower leg	0.118	0.0470	8.8e-05	0.046	NA	0.052	NA	0.039	9.9e-05	NA	3.8e-05	NA	3.4e-04
16	GTEx	Stomach	0.144	0.0800	8.6e-03	0.002	NA	0.006	NA	0.004	2.5e-01	NA	1.5e-01	NA	2.1e-01
17	GTEx	Testis	0.607	0.0670	0.0e+00	0.505	NA	0.584	NA	0.572	1.7e-25	NA	2.5e-31	NA	2.2e-30
18	GTEx	Thyroid	0.278	0.0610	1.1e-15	0.209	NA	0.231	NA	0.218	6.1e-16	NA	1.3e-17	NA	1.3e-16
19	ROSMAP	Brain Pre-frontal Cortex	0.233	0.0419	0.0e+00	0.246	0.26	0.289	0.287	0.299	2.7e-31	2.8e-33	1.7e-37	4e-37	7.4e-39

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	7	8	9	10	11	12	13	14	15	16	17	18	19
HbA1C	5.1	5.6	10.0	-2.6	-2.5	-2.6	2.9	2.0	1.4	2.5	2.4	3.1	2.5	3.2	2.7	2.8	2.1	1.7	1.6	2.8	-1.5
Waist Hip Ratio (WHR)	5.1	22.9	38.6	-5.6	-4.2	-4.2	6.2	2.7	3.1	5.1	5.2	5.7	5.1	5.2	5.5	5.4	5.6	5.5	4.0	5.3	-2.6
Vitamin and mineral supplements	5.0	6.8	15.9	-0.7	-0.0	-0.0	3.0	2.1	4.0	3.2	2.5	3.2	3.2	2.7	3.2	3.4	2.0	2.5	3.7	2.9	1.1
Multivitamins +/- minerals	4.8	6.1	13.1	0.8	-0.2	-0.2	-3.2	-1.6	-3.6	-2.9	-2.8	-3.0	-3.2	-2.4	-3.0	-3.1	-2.3	-1.9	-3.5	-2.8	-1.2
Neck or shoulder pain in last month	4.7	6.7	11.5	-2.5	-2.4	-2.3	2.8	1.2	2.4	3.2	2.6	3.3	2.9	2.8	3.3	3.2	3.4	0.7	2.1	3.3	-1.2
Asthma (self-reported)	4.7	9.4	15.4	3.6	3.7	3.8	-3.1	-0.1	-2.2	-3.7	-3.0	-3.7	-3.1	-3.9	-3.7	-3.6	-3.1	-1.1	-1.9	-3.7	2.5
Supplements: Vitamin C	4.5	5.4	11.3	1.2	0.7	0.7	-3.4	-3.1	-2.6	-2.6	-2.6	-2.7	-2.7	-2.6	-2.6	-2.7	-1.5	-2.4	-2.9	-2.6	-0.2
Unable to work because of sickness or disability	4.3	5.6	9.6	-3.1	-1.5	-1.5	3.0	1.9	1.9	2.4	2.9	2.8	2.9	2.4	2.5	2.7	2.7	2.7	2.1	2.9	-0.8
Chronic bronchitis/emphysema (mother)	4.2	4.9	12.9	-0.8	0.0	-0.0	3.4	3.6	3.1	2.1	2.3	2.3	2.4	1.9	2.2	2.4	1.5	2.2	3.2	2.1	0.9
Hearing difficulty/problems: Yes	3.8	5.9	11.1	-1.0	0.3	0.2	2.8	-0.8	3.2	2.9	2.8	2.9	3.1	2.4	2.9	2.9	3.1	1.9	3.3	2.8	1.4
Blood Red Count	3.7	35.4	59.4	-5.7	-5.3	-5.2	6.6	1.7	4.6	7.5	6.7	7.7	7.0	6.7	7.5	7.4	7.4	2.4	5.3	7.4	-2.7
Mouth/teeth dental problems	3.7	5.8	9.5	1.6	1.1	1.1	-3.0	-2.5	-2.7	-2.8	-3.1	-3.0	-3.1	-3.0	-3.0	-3.0	-1.6	-0.7	-2.6	-3.1	0.0
Supplements: Fish oil (including cod liver oil)	3.7	4.9	12.9	0.3	0.1	0.0	-2.7	-1.4	-3.6	-2.5	-2.6	-2.8	-2.8	-2.5	-2.5	-2.8	-1.9	-1.4	-3.1	-2.4	-1.1
Coronary Artery Disease (CAD)	3.6	4.3	8.2	-1.7	-1.1	-1.0	2.9	2.3	2.2	2.3	2.5	2.5	2.6	2.8	2.3	2.6	1.6	0.6	2.4	2.3	0.0
Asthma	3.6	7.2	12.7	3.2	3.5	3.6	-2.5	0.1	-1.9	-3.2	-2.6	-3.2	-2.6	-3.4	-3.2	-3.0	-2.5	-0.9	-1.4	-3.2	2.5
Mineral and other dietary supplements	3.2	4.3	10.2	0.7	0.4	0.4	2.6	2.1	3.2	2.2	2.1	2.3	2.3	2.0	2.1	2.3	2.1	2.5	3.2	2.0	1.3
High cholesterol (Self-reported)	3.1	5.5	25.8	-0.6	0.3	0.2	2.7	5.1	3.3	1.9	2.6	1.9	2.1	2.8	1.9	1.9	1.1	3.1	3.2	2.0	1.1
Ever had prostate specific antigen (PSA) test	3.1	3.5	12.1	-1.5	-2.4	-2.4	-1.8	-1.8	-3.5	-1.0	-1.5	-1.1	-1.9	-1.5	-1.0	-1.4	-0.2	-1.1	-3.0	-1.1	-3.1
Falls in the last year	3.0	4.1	10.0	-1.7	-2.3	-2.4	2.3	0.7	1.8	2.1	2.2	2.4	2.1	2.2	2.3	2.2	3.2	0.4	1.2	2.4	-1.7
Ever taken oral contraceptive pill	3.0	3.4	6.4	-2.5	-2.1	-2.1	2.1	0.4	1.5	1.9	1.8	2.0	1.5	1.6	1.8	1.7	2.5	2.3	1.6	1.9	-1.6
Heart disease (mother)	2.9	3.5	6.1	-1.5	-1.2	-1.3	2.5	1.8	1.6	2.1	2.5	2.1	2.2	2.5	2.2	2.1	2.1	0.7	1.8	2.3	-0.6
Worrier / anxious feelings	2.7	5.1	9.9	1.1	0.2	0.2	-2.7	-1.2	-3.0	-2.9	-3.1	-2.6	-2.9	-2.5	-2.8	-2.7	-1.8	-1.6	-3.0	-2.8	-1.0
Exposure to tobacco smoke at home	2.7	3.0	7.3	0.4	0.7	0.8	2.3	2.7	2.4	1.6	2.2	1.6	2.1	1.8	1.6	1.7	1.1	0.9	2.6	1.6	1.6
Diabetes (mother)	2.6	3.3	7.4	-1.5	-0.8	-0.8	2.7	0.6	1.7	1.9	2.6	1.8	2.1	2.1	1.8	2.0	2.3	2.3	2.2	2.0	0.0
Trunk fat percentage	2.6	10.3	19.6	-2.7	-2.5	-2.4	3.3	0.7	2.0	4.4	3.7	4.2	3.9	4.1	4.2	4.1	3.8	0.4	3.4	4.1	-1.0
Fed-up feelings	2.5	4.5	11.1	1.7	1.9	1.9	2.3	2.2	2.6	1.7	1.8	1.6	2.2	2.0	1.7	1.9	2.7	2.3	3.3	1.6	2.8
Alcohol usually taken with meals	2.5	4.0	8.5	0.7	-0.1	-0.1	-2.8	-2.4	-2.0	-2.2	-2.3	-2.3	-2.4	-2.3	-2.3	-2.3	-1.7	-1.9	-2.9	-2.1	-1.0
Pulse rate, automated reading	2.5	8.1	18.0	-1.1	0.2	0.2	4.0	2.9	4.0	3.1	2.9	3.1	3.4	2.9	3.2	3.2	2.2	3.0	4.2	3.3	1.5
Medication: Metformin	2.4	3.3	8.8	-1.0	0.5	0.5	2.5	1.3	2.2	1.8	1.9	1.8	2.1	1.8	1.8	1.8	1.8	2.7	3.0	1.8	1.2
Frequency of tiredness / lethargy in last 2 weeks	2.4	3.9	8.8	0.1	1.4	1.4	2.1	1.6	3.0	1.8	2.1	1.9	2.3	1.7	2.0	2.1	1.6	2.4	3.0	1.8	2.4
Body fat percentage	2.4	9.5	18.7	-2.5	-2.1	-2.1	3.2	1.1	1.9	4.3	3.5	4.1	3.8	3.9	4.1	4.0	3.5	0.4	3.5	3.9	-0.7
Illness, injury, bereavement, stress in last 2 years	2.4	2.9	6.0	-1.6	-1.0	-1.0	2.4	1.1	1.3	2.1	2.1	1.9	2.0	1.7	1.8	1.9	2.5	1.3	2.0	2.0	-0.4
Mother’s age at death	2.4	3.0	8.6	-1.4	-2.1	-2.0	-1.9	-1.6	-1.8	-1.4	-1.6	-1.5	-1.9	-1.5	-1.3	-1.6	-1.3	-1.4	-2.9	-1.1	-2.6
Type 2 Diabetes (T2D) (2018)	2.3	4.3	12.0	-1.5	0.1	0.1	2.9	2.2	2.1	2.1	1.8	2.2	2.2	1.9	2.1	2.2	2.1	3.5	3.1	2.1	0.9
Hair/balding pattern: Pattern 2	2.3	2.9	8.2	2.7	2.9	2.9	-0.7	2.3	0.3	-1.6	-0.9	-1.8	-1.2	-1.0	-1.5	-1.5	-1.7	0.4	0.5	-1.8	2.5
Number of live births	2.3	3.2	6.1	-1.8	-1.2	-1.1	2.5	2.0	2.4	1.7	1.9	2.1	2.0	1.5	2.0	2.0	1.9	1.4	1.8	2.2	-0.5
Qualifications: College or University degree	2.3	7.1	14.0	0.6	-0.2	-0.2	-3.4	-2.2	-3.7	-3.1	-3.6	-2.9	-3.6	-3.3	-3.0	-3.4	-1.3	-1.3	-3.7	-3.1	-1.6
Major Depression (MDD)	2.2	2.7	14.1	0.7	-0.0	-0.1	-1.7	-3.8	-1.7	-1.8	-1.8	-1.5	-1.9	-1.5	-1.8	-1.7	-1.3	-0.3	-2.1	-1.6	-0.7
Impedance of arm (right)	2.2	10.3	22.3	-2.7	-1.5	-1.4	4.7	3.8	3.1	3.5	3.8	3.8	3.9	4.0	3.7	3.7	3.2	1.3	3.5	3.8	-0.1
Leg fat percentage (right)	2.2	7.9	16.5	-1.4	-1.1	-1.1	2.8	2.3	2.2	4.1	3.0	3.8	3.6	3.7	3.8	3.7	2.6	-0.3	3.8	3.5	0.4
Diabetes diagnosed by doctor	2.2	3.6	11.0	-0.9	0.2	0.2	2.6	1.6	2.1	2.0	1.6	2.0	2.0	1.9	2.0	1.9	1.9	3.3	3.0	1.9	0.9
Average weekly beer plus cider intake	2.2	3.2	7.7	0.1	0.1	0.1	2.1	2.8	2.1	1.9	1.9	2.0	2.1	2.3	1.8	1.9	1.1	1.7	2.6	1.8	1.1
Eye problems/disorders: Diabetes related eye disease	2.1	2.4	8.0	0.2	1.2	1.2	1.7	0.7	1.8	2.0	1.1	1.6	1.8	1.4	1.7	1.7	1.2	1.0	2.8	1.5	2.0
Qualifications: A levels/AS levels or equivalent	2.1	4.6	9.4	1.1	0.3	0.3	-3.1	-2.1	-2.7	-2.4	-2.9	-2.5	-2.9	-2.8	-2.4	-2.6	-1.4	-0.8	-2.5	-2.5	-0.6
Loud music exposure frequency	2.1	2.3	4.2	-1.2	-0.7	-0.7	2.0	1.9	1.6	1.6	2.0	1.8	1.8	1.6	1.8	1.6	1.1	1.8	1.7	1.6	-0.1
Impedance of leg (right)	2.0	9.7	32.3	-1.6	-1.0	-0.9	4.0	5.7	3.0	3.3	3.5	3.5	3.8	4.4	3.4	3.5	2.5	0.5	3.6	3.4	0.4
Supplements: Glucosamine	2.0	2.6	7.4	-1.3	-1.4	-1.4	-1.9	-1.4	-2.5	-1.5	-1.5	-1.3	-1.7	-1.2	-1.3	-1.4	-1.7	-1.4	-2.7	-1.3	-2.1
Past tobacco smoking	2.0	3.6	7.8	1.4	-0.0	0.0	-2.8	0.3	-2.0	-2.1	-2.5	-2.4	-2.7	-1.6	-2.2	-2.5	-1.4	-1.4	-2.5	-2.3	-1.1
Alcohol intake versus 10 years previously	2.0	3.0	6.7	-1.9	-1.4	-1.4	1.7	-1.2	1.1	2.2	2.0	2.2	2.0	2.6	2.1	2.2	1.7	-0.4	1.2	2.2	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.1	5.8	2.4	1.5	1.5	-2.2	-0.8	-1.4	-2.1	-2.2	-2.4	-2.2	-1.5	-2.2	-2.2	-1.4	0.1	-1.6	-2.3	0.6
Number of full brothers	2.0	2.5	6.0	0.0	1.1	1.1	1.9	1.4	2.0	1.6	2.3	1.4	2.1	2.0	1.5	1.8	0.9	0.7	2.4	1.6	1.7
Smoking status: Previous	2.0	3.0	6.6	-1.6	-0.5	-0.5	2.6	-0.2	1.4	1.9	2.2	2.2	2.4	1.5	2.1	2.3	1.4	1.4	2.0	2.2	0.5
Respiratory disease	1.9	4.2	9.6	1.8	2.0	2.0	-2.0	-0.2	-2.1	-2.6	-1.9	-2.5	-2.2	-3.1	-2.5	-2.6	-2.1	-0.0	-1.7	-2.6	1.0
Medication: Ventolin 100micrograms inhaler	1.9	2.4	5.3	2.3	2.0	1.9	-1.5	-0.2	-0.9	-2.0	-1.4	-2.0	-1.6	-1.6	-1.9	-1.8	-1.3	0.7	-0.9	-1.9	1.3
Irritability	1.9	3.2	8.3	-0.5	-0.2	-0.1	2.7	1.1	2.1	1.9	2.0	2.1	2.2	1.8	1.9	2.0	2.9	0.4	2.5	2.0	0.7
Alcohol drinker status: Previous	1.9	2.1	15.4	-1.4	-0.8	-0.8	1.9	0.1	0.4	1.1	1.5	1.2	1.2	1.4	1.3	1.1	1.7	3.9	1.1	1.3	-0.5
Impedance of whole body	1.9	9.6	19.1	-2.5	-1.5	-1.4	4.4	4.4	2.8	3.2	3.7	3.5	3.8	4.1	3.4	3.5	3.1	1.0	3.3	3.5	-0.2
Systolic Blood Pressure	1.8	8.9	15.9	2.6	1.9	1.9	-3.2	-1.9	-2.8	-4.0	-3.1	-3.7	-3.6	-3.4	-4.0	-3.7	-3.8	-1.1	-3.1	-3.7	0.5
Systolic blood pressure, automated reading	1.8	5.3	8.4	2.0	1.0	1.0	-2.9	-2.0	-2.8	-2.6	-2.4	-2.7	-2.8	-2.6	-2.9	-2.7	-2.7	-1.6	-2.6	-2.8	-0.0
Current tobacco smoking	1.8	2.9	5.0	-0.7	-0.7	-0.7	2.0	1.2	2.0	2.2	1.8	2.0	2.0	2.2	2.1	2.0	2.0	1.7	2.1	2.0	0.1
Mouth/teeth dental problems: Dentures	1.8	3.0	7.5	-2.7	-1.8	-1.8	1.9	-0.4	1.0	1.9	2.2	2.2	1.9	1.9	2.1	2.0	0.4	1.4	1.0	2.2	-1.2
Shortness of breath walking on level ground	1.8	2.1	5.2	2.3	1.3	1.3	-1.7	-0.8	-0.7	-1.7	-1.7	-1.6	-1.7	-1.7	-1.6	-1.7	-1.6	-1.1	-0.9	-1.8	0.7
Leg fat percentage (left)	1.8	6.7	14.4	-1.1	-0.7	-0.7	2.6	1.8	2.1	3.8	2.8	3.5	3.4	3.3	3.5	3.5	2.4	-0.1	3.7	3.2	0.7
Pain experienced in last month	1.8	2.9	6.5	2.3	2.2	2.1	-1.3	-0.4	-1.1	-2.1	-1.2	-2.0	-1.6	-1.9	-2.1	-2.0	-2.5	-0.1	-0.8	-2.0	1.5
Serious illness, injury or assault to yourself	1.7	2.0	4.7	1.4	1.2	1.1	-2.2	-1.3	-0.5	-1.7	-2.0	-1.4	-1.6	-1.7	-1.5	-1.4	-1.8	-0.3	-1.6	-1.6	0.5
Impedance of leg (left)	1.7	8.2	26.4	-1.2	-0.6	-0.6	3.7	5.1	2.9	3.0	3.3	3.2	3.5	4.0	3.0	3.2	2.3	0.8	3.4	3.0	0.6
Qualifications: None of the above	1.7	3.6	7.0	-1.1	-0.5	-0.4	2.4	0.5	1.6	2.5	2.2	2.5	2.6	2.3	2.5	2.6	1.4	0.8	2.2	2.6	0.4
Diabetes (self-reported)	1.7	2.7	9.4	-0.6	0.4	0.4	2.2	1.9	2.0	1.5	1.4	1.6	1.7	1.7	1.6	1.6	1.4	3.1	2.5	1.5	1.0
Pulse rate	1.7	2.9	7.5	-0.9	0.6	0.6	2.5	0.4	2.6	1.7	1.7	1.8	2.1	1.4	1.9	1.9	1.3	1.5	2.7	1.9	1.5
Trunk predicted mass	1.7	9.8	24.7	0.3	-1.4	-1.4	-4.9	-3.7	-3.4	-3.2	-3.1	-3.2	-4.0	-2.6	-3.2	-3.5	-3.4	-2.0	-5.0	-3.1	-3.0
Age at first live birth	1.7	3.0	7.4	1.1	0.5	0.5	-2.3	-0.7	-1.3	-1.9	-2.2	-1.8	-2.1	-1.8	-1.9	-1.9	-2.7	-2.3	-2.1	-2.0	-0.2
Illnesses of siblings: Diabetes	1.7	2.0	5.2	-0.9	-1.1	-1.1	1.7	0.2	0.7	1.7	2.2	1.9	1.8	2.3	1.8	1.8	1.2	0.3	1.3	1.8	-0.5
Bilateral oophorectomy (both ovaries removed)	1.6	1.8	3.3	-1.0	-0.7	-0.7	1.5	0.4	1.3	1.7	1.8	1.5	1.6	1.7	1.6	1.5	1.8	1.4	1.5	1.6	-0.1
Arm fat percentage (right)	1.6	6.4	13.5	-2.0	-1.3	-1.4	2.7	0.6	1.6	3.7	2.6	3.5	3.1	2.8	3.4	3.3	2.9	0.8	3.2	3.3	-0.1
Trunk fat-free mass	1.6	9.4	23.8	0.2	-1.4	-1.4	-4.8	-3.7	-3.3	-3.1	-3.0	-3.1	-3.8	-2.5	-3.1	-3.4	-3.3	-2.2	-4.9	-3.0	-3.0
Ever had bowel cancer screening	1.6	1.9	3.9	0.9	0.5	0.5	-1.7	-1.9	-1.7	-1.7	-1.4	-1.5	-1.6	-2.0	-1.5	-1.6	-0.9	-0.3	-1.9	-1.5	-0.1
Fractured/broken bones in last 5 years	1.6	2.0	7.2	0.6	1.0	1.0	1.2	2.7	2.4	1.5	0.8	1.2	1.6	0.8	1.4	1.5	0.4	0.0	2.0	1.4	1.7
Alzheimer’s Disease (in mother)	1.5	1.8	3.3	1.4	1.0	1.0	-1.5	-0.4	-1.2	-1.4	-1.7	-1.7	-1.8	-1.3	-1.6	-1.7	-1.4	-1.0	-1.0	-1.8	0.5
Chronotype (morning person)	1.5	3.5	7.7	0.9	0.5	0.5	-1.8	-2.0	-2.1	-2.4	-2.8	-2.3	-2.5	-2.5	-2.3	-2.4	-0.7	-0.1	-2.1	-2.4	-0.6
Impedance of arm (left)	1.5	6.9	14.4	-2.9	-1.9	-1.9	3.8	2.8	1.9	2.8	3.0	3.0	3.1	3.3	3.0	2.9	3.0	0.7	2.4	3.0	-0.9
Forced vital capacity (FVC), Best measure	1.5	5.4	20.9	-2.9	-3.8	-3.8	-2.0	-0.6	-1.7	-0.9	-0.2	-0.5	-1.2	0.5	-0.7	-0.8	-2.1	-3.6	-3.9	-0.3	-4.6
Number of children fathered	1.5	1.7	3.8	-1.6	-1.3	-1.3	1.2	-0.3	0.7	1.9	1.2	1.6	1.4	1.7	1.7	1.5	1.0	-0.5	1.0	1.6	-0.7
Comparative height size at age 10	1.5	8.0	31.5	-3.2	-4.5	-4.5	-2.3	-3.6	-3.5	-1.3	-1.5	-1.1	-2.2	-0.9	-1.0	-1.5	-0.6	-1.6	-4.6	-0.9	-5.6
Suffer from ‘nerves’	1.5	2.3	5.8	0.6	1.2	1.2	1.6	2.2	2.2	1.4	1.4	1.4	1.8	1.6	1.4	1.5	1.3	0.6	2.4	1.4	1.9
Knee pain experienced in last month	1.5	2.3	6.9	-2.0	-2.0	-2.1	1.6	-0.8	0.8	1.6	1.0	1.7	1.3	0.9	1.7	1.6	2.6	1.0	0.6	1.6	-1.5
Medication: Atorvastatin	1.5	1.8	5.4	0.8	0.2	0.2	2.0	1.8	1.4	1.4	1.6	1.3	1.6	1.3	1.3	1.3	1.8	0.9	2.3	1.3	0.8
Tinnitus: Yes, but not now, but have in the past	1.4	1.4	3.5	0.8	0.4	0.4	0.9	1.9	0.7	1.7	1.0	1.2	1.4	1.6	1.5	1.5	0.8	-1.4	1.3	1.3	1.1
Sitting height	1.4	9.7	26.0	-0.0	-1.9	-1.9	-4.5	-3.4	-2.6	-3.2	-2.6	-3.1	-3.7	-2.1	-3.1	-3.4	-3.7	-3.3	-5.1	-3.0	-3.5
Allergy	1.4	3.1	8.0	-2.3	-2.8	-2.8	1.3	-0.4	0.5	2.0	1.1	2.1	1.3	2.2	1.9	1.8	2.0	0.9	0.4	1.8	-2.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.4	18.5	-3.1	-3.7	-3.7	-1.5	-0.6	-1.3	-0.4	0.2	-0.1	-0.8	0.8	-0.2	-0.5	-1.7	-3.0	-3.3	0.0	-4.3
Gout (self-reported)	1.4	2.0	3.7	-1.6	-1.3	-1.3	1.9	1.7	0.6	1.4	1.9	1.6	1.6	1.6	1.5	1.5	1.1	1.0	1.2	1.7	-0.8
Medication: Omeprazole	1.4	1.7	3.3	-1.0	-0.4	-0.4	1.8	0.6	1.2	1.6	1.3	1.8	1.6	1.0	1.6	1.8	1.6	1.0	1.8	1.5	0.2
Leg pain on walking	1.4	1.7	4.5	-0.7	-0.3	-0.4	1.4	0.2	2.1	1.6	1.3	1.7	1.8	1.4	1.6	1.8	1.7	-0.3	1.3	1.6	0.3
Arm fat percentage (left)	1.4	5.7	12.2	-2.1	-1.6	-1.6	2.5	0.2	1.3	3.5	2.4	3.3	2.9	2.6	3.2	3.1	3.0	0.6	2.8	3.0	-0.5
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	5.6	-0.4	-1.1	-1.1	1.3	0.5	0.5	2.2	0.9	2.1	1.7	1.8	2.0	2.0	2.4	-1.1	1.5	1.8	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.7	4.8	-0.7	0.1	0.1	1.8	1.6	1.6	1.3	1.1	1.4	1.5	0.8	1.4	1.5	1.1	2.2	1.6	1.3	0.7
Triglycerides	1.3	2.2	14.4	1.4	1.2	1.2	1.3	3.8	1.7	0.9	1.0	0.9	1.2	1.0	0.8	1.0	0.8	1.2	2.0	0.7	1.9
Ever had hysterectomy (womb removed)	1.3	1.5	3.1	-0.1	-0.0	-0.0	1.2	1.0	1.7	1.4	1.5	1.4	1.5	1.5	1.4	1.5	1.2	1.1	1.8	1.5	0.7
Waist circumference	1.3	4.7	8.2	-2.4	-2.3	-2.3	2.0	-0.2	0.9	2.9	2.1	2.8	2.2	2.5	2.7	2.6	2.6	1.7	2.0	2.6	-1.5
Forced vital capacity (FVC)	1.3	5.1	23.1	-2.9	-3.9	-3.9	-1.7	-0.5	-1.6	-1.1	-0.1	-0.5	-1.2	0.4	-0.7	-0.8	-1.4	-2.9	-3.8	-0.3	-4.8
Forced expiratory volume in 1-second (FEV1)	1.3	4.3	18.7	-2.9	-3.6	-3.6	-1.7	-0.8	-1.4	-0.7	0.0	-0.4	-1.0	0.5	-0.4	-0.7	-1.2	-2.7	-3.3	-0.2	-4.3
Ever highly irritable/argumentative for 2 days	1.3	1.6	3.0	-0.3	0.1	0.1	1.6	1.5	1.5	1.5	1.4	1.4	1.6	1.7	1.5	1.5	1.1	0.6	1.7	1.4	0.7
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	13.8	0.2	0.2	0.2	1.8	3.7	1.7	0.4	2.0	0.8	1.3	1.2	0.7	1.0	0.4	1.1	1.1	0.9	0.5
Arm fat-free mass (right)	1.3	6.8	17.8	0.3	-1.5	-1.5	-4.2	-3.8	-2.9	-2.4	-2.5	-2.5	-3.2	-2.0	-2.5	-2.8	-2.3	-1.7	-4.1	-2.4	-2.8
Arm predicted mass (right)	1.3	6.9	17.8	0.5	-1.4	-1.4	-4.2	-3.8	-2.8	-2.5	-2.4	-2.6	-3.2	-2.1	-2.6	-2.8	-2.3	-1.7	-4.0	-2.5	-2.7
Eye problems/disorders: Cataract	1.3	1.5	4.8	-1.5	-1.2	-1.2	1.2	1.9	0.8	1.1	0.9	1.1	1.0	1.1	1.1	1.1	1.7	2.2	0.8	1.1	-0.9
Cholesterol lowering medication	1.3	2.0	8.3	0.9	1.7	1.6	1.2	2.9	1.9	0.5	1.1	0.6	1.0	1.2	0.7	0.7	0.2	1.7	2.1	0.8	2.0
Heart disease (siblings)	1.3	1.7	3.2	1.4	1.2	1.2	-1.7	-1.0	-1.2	-1.3	-1.8	-1.3	-1.2	-1.7	-1.2	-1.2	-1.3	-1.2	-1.3	-1.4	0.8
LDL Cholesterol	1.2	1.9	28.6	1.0	0.7	0.8	0.8	5.3	0.8	0.1	0.2	0.2	0.3	1.0	0.0	0.2	0.6	0.4	1.2	0.0	0.8
Relative age of first facial hair	1.2	2.5	5.2	2.3	1.7	1.7	-1.9	-1.2	-0.8	-1.6	-1.8	-1.8	-1.8	-1.8	-1.8	-1.9	-1.1	-0.2	-0.6	-2.1	1.2
Diabetes (father)	1.2	1.5	4.8	0.2	0.6	0.6	1.8	0.8	1.6	1.4	1.6	1.3	1.5	1.1	1.1	1.1	1.1	-0.3	2.2	1.2	1.1
Trunk fat mass	1.2	5.3	10.2	-2.4	-2.5	-2.5	1.7	-0.2	1.0	3.2	2.5	3.0	2.5	3.0	3.0	2.8	2.5	-0.3	1.8	2.9	-1.6
Happiness	1.2	1.5	6.2	2.5	1.8	1.8	-1.2	-0.4	-0.3	-1.0	-1.2	-1.2	-0.9	-1.3	-1.2	-1.0	-0.7	-0.9	-0.3	-1.2	1.4
Mouth/teeth dental problems: Loose teeth	1.2	1.4	3.4	-1.2	-0.5	-0.6	1.0	-0.9	1.0	1.6	1.2	1.8	1.6	1.1	1.7	1.7	0.9	0.2	1.0	1.8	0.1
Whole body fat-free mass	1.2	7.0	17.4	0.1	-1.5	-1.5	-4.1	-3.9	-2.9	-2.4	-2.5	-2.5	-3.2	-2.1	-2.5	-2.8	-2.5	-2.0	-4.2	-2.4	-2.8
Whole body water mass	1.2	7.0	17.5	0.1	-1.5	-1.5	-4.1	-3.9	-2.9	-2.4	-2.5	-2.5	-3.2	-2.1	-2.5	-2.8	-2.5	-2.0	-4.2	-2.4	-2.8
Schizophrenia vs Biploar Disorder	1.1	1.5	3.4	0.7	0.8	0.7	-1.8	-1.5	-1.0	-1.0	-1.6	-1.6	-1.4	-1.8	-1.2	-1.3	-0.7	-1.4	-1.2	-1.3	0.4
Fasting Glucose	1.1	1.3	2.9	-0.6	-0.5	-0.5	0.9	-0.3	1.2	1.7	1.6	1.5	1.5	1.5	1.7	1.6	0.6	0.1	1.4	1.4	0.2
Primary Biliary Cirrhosis	1.1	1.5	4.3	-0.3	0.6	0.5	1.7	-0.2	1.8	1.5	1.5	1.2	1.6	1.0	1.3	1.4	1.1	0.6	2.1	1.2	1.2
Frequency of depressed mood in last 2 weeks	1.1	1.6	3.1	-0.3	0.1	0.1	1.7	1.5	1.6	1.2	1.6	1.4	1.4	1.0	1.2	1.2	1.7	1.8	1.7	1.2	0.6
Maternal smoking around birth	1.1	1.6	4.5	1.4	2.1	2.1	1.2	1.8	1.7	-0.1	0.1	-0.0	0.2	-0.4	-0.1	0.0	-0.3	2.1	1.7	-0.3	2.0
Had menopause	1.1	1.3	5.4	1.4	2.1	2.1	-0.1	1.9	1.3	-0.1	-0.2	-0.2	0.1	0.0	-0.1	-0.0	-0.8	1.1	1.2	-0.3	2.3
Whole body fat mass	1.1	4.6	9.3	-2.0	-2.2	-2.2	1.7	-0.2	0.9	3.0	2.3	2.9	2.4	2.8	2.8	2.7	2.4	-0.1	1.9	2.7	-1.3
Qualifications: nursing, teaching	1.1	1.7	4.9	-0.3	-0.8	-0.8	-2.2	-1.3	-1.8	-1.2	-1.8	-1.1	-1.8	-1.1	-1.1	-1.4	-0.7	0.1	-1.9	-1.4	-1.3
Medication: Gliclazide	1.1	1.2	4.5	-0.9	-0.1	-0.0	1.3	1.8	1.2	0.9	0.8	1.1	1.0	1.1	1.1	1.1	0.5	2.1	1.6	1.0	0.3
Smoking status: Current	1.1	1.8	3.8	-0.5	-0.2	-0.3	1.6	0.8	2.0	1.7	1.4	1.5	1.6	1.7	1.6	1.6	1.4	1.3	1.7	1.5	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	9.1	-0.9	-1.6	-1.6	-2.1	-1.0	-1.7	-0.9	-0.7	-0.8	-1.1	-0.4	-0.8	-1.0	-1.7	-3.0	-2.7	-0.7	-2.3
Ever smoked	1.1	1.9	4.1	-0.9	-0.4	-0.5	1.8	-0.9	1.3	1.6	2.0	1.8	2.0	1.4	1.7	1.8	1.4	0.6	1.6	1.7	0.3
Arm fat-free mass (left)	1.1	5.8	15.5	0.5	-1.3	-1.3	-3.9	-3.2	-2.6	-2.3	-2.2	-2.3	-3.0	-1.8	-2.3	-2.6	-2.6	-1.7	-3.7	-2.3	-2.5
Alzheimer’s Disease (including proxy)	1.0	1.5	2.8	1.2	0.7	0.7	-1.0	0.2	-1.3	-1.4	-1.5	-1.5	-1.7	-1.5	-1.4	-1.6	-1.4	-0.4	-1.1	-1.7	0.2
Rheumatoid Arthritis	1.0	1.4	2.8	1.0	1.2	1.3	-0.7	-1.3	-0.6	-1.7	-1.1	-1.4	-1.4	-1.5	-1.6	-1.6	-1.0	0.4	-0.5	-1.6	0.6
Ever used hormone-replacement therapy (HRT)	1.0	1.2	4.0	-0.1	0.1	0.1	1.3	1.2	0.9	1.0	1.4	1.1	1.2	1.4	1.1	1.0	1.6	2.0	1.4	0.9	0.5
Supplements: Zinc	1.0	1.1	4.4	1.9	2.1	2.1	-0.5	-0.5	0.3	-0.7	-0.2	-1.0	-0.3	-0.3	-0.8	-0.7	-0.9	-0.7	0.3	-0.8	2.0
Medication: Ramipril	1.0	1.3	5.9	0.9	1.0	1.0	-0.5	0.6	-0.4	-1.4	-1.5	-1.2	-1.4	-1.3	-1.3	-1.4	-0.3	2.4	-0.6	-1.3	0.5
Birth weight	1.0	2.1	8.9	-1.0	-1.4	-1.4	-1.5	-3.0	-1.6	-0.8	-0.7	-0.8	-1.1	-0.7	-0.8	-1.0	-2.3	-1.5	-2.1	-0.7	-1.8
Pulse wave peak to peak time	1.0	1.2	3.3	0.3	-1.2	-1.2	-1.3	0.4	-1.7	-0.9	-1.2	-0.7	-1.2	-0.2	-0.8	-0.9	-1.4	-1.0	-1.8	-1.0	-1.5
Number of full sisters	1.0	1.3	5.1	0.1	0.7	0.7	1.1	-1.6	1.8	0.8	1.2	0.8	1.0	0.7	0.8	0.9	1.1	2.3	1.6	0.9	1.0
Commuting to job workplace: Walk	1.0	1.1	8.6	-0.7	-1.3	-1.4	-0.3	-2.9	-1.2	0.1	0.1	0.2	-0.2	0.4	0.2	0.2	-0.2	-1.6	-1.1	0.2	-1.5
Osteoarthritis (self-reported)	1.0	1.3	5.7	-2.4	-2.1	-2.1	0.5	0.8	-0.3	0.8	0.1	0.8	0.3	0.5	0.8	0.6	1.4	1.1	-0.4	0.7	-2.0
Tinnitus: Yes, now most or all of the time	1.0	1.1	6.2	0.4	0.3	0.3	-1.5	-2.5	-0.9	-0.9	-0.8	-1.1	-1.0	-1.4	-1.0	-1.0	-0.9	-1.1	-1.1	-0.9	-0.2
Commuting to job workplace: Cycle	1.0	1.2	2.6	1.1	1.6	1.6	-1.0	-0.6	-0.0	-1.3	-0.7	-1.2	-0.9	-1.6	-1.2	-1.0	-1.4	0.1	-0.5	-1.1	1.1
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	2.4	-0.7	-0.3	-0.3	1.4	0.1	1.2	1.5	1.1	1.5	1.4	0.8	1.4	1.5	1.3	0.0	1.6	1.3	0.4
Age at First Birth	0.9	1.3	2.9	1.5	1.3	1.3	-1.3	1.4	-0.8	-1.2	-0.9	-1.1	-0.8	-1.0	-1.2	-1.0	-1.3	-1.7	-0.8	-1.1	0.9
Sensitivity / hurt feelings	0.9	1.6	4.2	0.8	0.7	0.7	2.0	1.1	1.4	0.9	2.1	1.1	1.7	1.4	1.0	1.3	1.5	0.2	1.8	1.1	1.1
Pain all over the body in last month	0.9	0.9	2.9	-1.3	-1.7	-1.7	0.9	0.9	0.2	0.6	0.9	0.8	0.7	0.8	0.8	0.9	0.7	0.0	-0.2	0.9	-1.6
Breastfed as a baby	0.9	1.1	14.4	-0.4	-0.2	-0.2	-0.7	-3.8	-0.5	-0.5	-0.7	-0.6	-0.7	-1.2	-0.6	-0.7	-0.5	0.2	-0.9	-0.6	-0.5
Exposure to tobacco smoke outside home	0.9	1.2	3.3	-0.0	0.7	0.7	1.5	0.2	1.5	1.4	1.5	1.0	1.5	1.1	1.2	1.3	-0.3	0.1	1.8	1.3	1.3
Leg fat mass (right)	0.9	3.6	8.7	-1.1	-1.2	-1.2	1.5	0.6	1.2	3.0	2.1	2.7	2.4	2.6	2.6	2.5	1.8	-0.6	2.3	2.5	-0.3
Chest pain or discomfort	0.9	1.3	5.3	0.7	0.6	0.6	1.2	2.3	1.4	1.0	1.0	1.2	1.2	0.8	1.1	1.1	0.8	0.9	1.9	1.0	1.2
Leg fat-free mass (right)	0.9	4.7	18.1	-0.1	-1.4	-1.4	-3.2	-4.2	-2.5	-1.7	-1.8	-1.8	-2.4	-1.8	-1.8	-2.0	-1.5	-1.7	-3.3	-1.7	-2.5
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	6.0	-0.3	-0.2	-0.3	1.1	1.2	1.5	0.7	0.8	0.8	0.8	0.8	0.9	0.8	0.7	2.4	0.7	0.9	0.1
Leg predicted mass (right)	0.9	4.7	17.4	-0.0	-1.4	-1.4	-3.3	-4.2	-2.5	-1.8	-1.9	-1.8	-2.5	-1.8	-1.8	-2.1	-1.5	-1.6	-3.3	-1.8	-2.4
Basal metabolic rate	0.9	4.7	11.8	-0.1	-1.6	-1.7	-3.4	-3.4	-2.5	-1.7	-1.8	-1.8	-2.5	-1.5	-1.8	-2.1	-1.8	-1.9	-3.4	-1.8	-2.7
Arm predicted mass (left)	0.9	4.3	12.5	0.5	-1.1	-1.1	-3.5	-2.7	-2.1	-2.0	-1.9	-2.0	-2.6	-1.6	-2.0	-2.2	-2.2	-1.5	-3.2	-2.0	-2.1
Depression (Nagel 2018)	0.8	1.1	3.0	-1.1	-0.7	-0.8	1.4	0.8	1.2	1.0	1.7	1.2	1.2	1.0	1.1	1.1	1.3	1.1	1.0	1.0	-0.4
Bipolar Disorder (2011)	0.8	0.7	1.9	-0.5	-0.3	-0.3	1.4	0.8	1.1	0.8	0.9	1.1	1.0	1.0	0.9	1.1	0.3	0.8	1.2	1.0	-0.0
Lung FVC	0.8	3.9	15.8	-2.1	-3.2	-3.2	-1.7	-0.1	-2.1	-0.8	-0.4	-0.7	-1.2	0.3	-0.7	-0.9	-1.8	-2.7	-3.2	-0.4	-4.0
Medication for hormone replacement therapy	0.8	0.9	1.8	-0.6	-0.4	-0.4	1.1	0.6	1.3	1.0	0.8	1.1	1.1	1.2	1.1	1.0	1.3	1.3	1.2	1.0	0.1
Hearing difficulty/problems with background noise	0.8	1.3	4.7	0.5	1.8	1.8	0.9	-0.7	1.6	0.7	0.7	0.6	1.0	0.3	0.7	0.7	0.8	1.1	2.0	0.6	2.2
Medication: Simvastatin	0.8	1.2	6.5	-0.9	0.6	0.5	1.1	1.6	1.9	0.5	1.0	0.7	0.9	0.9	0.7	0.7	-0.0	2.5	1.2	0.9	0.7
Hair/balding pattern: Pattern 3	0.8	1.2	4.3	-1.6	-2.1	-2.1	0.6	-0.2	0.1	0.6	0.6	1.2	0.6	1.1	0.7	0.9	-0.3	-0.6	-0.8	0.9	-1.9
Noisy workplace	0.8	1.0	2.3	-0.8	0.0	-0.0	1.4	-0.2	1.0	1.2	1.5	0.9	1.2	1.5	0.9	1.0	0.6	1.1	1.2	1.2	0.4
Medication: Cholesterol lowering	0.8	1.3	3.8	-0.4	0.5	0.5	1.2	1.7	1.9	1.2	0.9	1.1	1.3	1.1	1.1	1.1	0.3	1.4	1.7	1.1	1.1
Illnesses of mother	0.8	0.9	4.5	-0.1	-0.9	-0.9	-1.3	-0.7	-2.1	-0.8	-1.1	-0.5	-1.0	-0.5	-0.7	-0.7	-0.4	-0.7	-1.6	-0.8	-1.2
Hair/balding pattern: Pattern 4	0.8	1.9	6.9	-2.6	-2.1	-2.0	1.1	-1.2	-1.2	0.6	0.0	0.7	0.2	-0.1	0.7	0.5	2.1	2.5	-0.3	0.8	-2.0
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.7	0.2	-0.1	-0.1	-1.2	0.1	-1.6	-1.0	-1.3	-0.9	-1.1	-0.8	-1.0	-1.0	-1.1	-1.6	-1.3	-0.8	-0.5
Medication: Seretide 50 evohaler	0.8	0.9	1.6	0.7	0.9	0.9	-1.1	0.0	-1.3	-1.3	-1.2	-1.0	-0.9	-1.1	-1.0	-1.1	-1.1	0.3	-1.1	-1.0	0.5
Basal cell carcinoma (self-reported)	0.8	0.9	4.8	0.9	1.4	1.3	-0.1	-0.2	0.1	-0.7	-1.1	-0.6	-0.6	-1.1	-0.7	-0.8	-1.1	2.2	0.1	-0.7	1.4
Leg fat mass (left)	0.8	3.2	7.9	-0.9	-1.1	-1.1	1.4	0.4	1.1	2.8	1.9	2.5	2.2	2.4	2.5	2.4	1.7	-0.4	2.2	2.3	-0.2
Bipolar Disorder (2018)	0.7	1.1	3.7	-0.1	0.4	0.4	1.7	1.9	1.2	0.9	0.6	1.0	0.9	1.2	0.7	0.8	0.4	1.7	1.7	0.8	0.7
Bipolar Disorder or Schizophrenia	0.7	1.7	3.7	-1.6	-0.4	-0.4	1.9	1.2	1.1	1.6	1.3	1.7	1.5	1.5	1.5	1.5	0.7	1.4	1.8	1.5	0.3
Lupus	0.7	1.1	3.4	1.0	1.3	1.4	0.7	0.4	1.7	1.1	0.4	0.5	1.0	0.9	0.7	0.9	0.4	-0.7	1.6	0.7	1.8
Blood Eosinophil Count	0.7	5.1	20.1	3.1	4.3	4.2	0.7	2.8	2.9	-0.4	0.8	-0.6	0.5	0.1	-0.6	-0.2	-1.1	1.4	3.1	-0.6	4.5
Height	0.7	14.1	67.7	-4.3	-6.9	-6.8	-2.7	-2.6	-2.9	-1.6	-0.4	-0.9	-2.2	0.8	-1.1	-1.7	-1.1	-3.2	-6.2	-0.6	-8.2
Smoking Status	0.7	1.6	4.4	0.1	0.8	0.7	1.6	-0.5	1.9	1.2	1.3	1.2	1.6	1.0	1.2	1.4	0.7	2.1	1.8	1.2	1.4
Leg fat-free mass (left)	0.7	3.6	13.5	-0.4	-1.8	-1.8	-2.8	-3.7	-2.2	-1.2	-1.4	-1.3	-2.0	-1.2	-1.3	-1.6	-1.1	-1.8	-2.9	-1.2	-2.6
Hand grip strength (right)	0.7	2.0	8.6	-2.1	-2.9	-2.9	-0.0	-0.7	-0.0	0.6	1.0	1.1	0.4	1.4	0.9	0.8	0.3	-0.9	-1.0	1.0	-2.8
Townsend deprivation index at recruitment	0.7	1.0	4.5	-0.2	0.5	0.5	1.7	0.0	0.9	0.9	1.2	0.7	1.1	0.3	0.8	0.9	1.2	2.1	1.2	0.9	0.7
Leg predicted mass (left)	0.7	3.8	13.4	-0.3	-1.7	-1.7	-2.9	-3.7	-2.2	-1.4	-1.5	-1.4	-2.1	-1.3	-1.4	-1.7	-1.3	-1.8	-3.0	-1.4	-2.6
Prospective memory result	0.7	0.9	3.1	1.1	0.6	0.6	-1.4	-0.2	-0.3	-0.8	-1.4	-0.9	-1.0	-1.0	-0.9	-0.8	-1.8	-1.2	-0.8	-0.9	0.3
Pulse wave Arterial Stiffness index	0.7	0.8	2.2	-0.4	0.9	0.9	1.0	-0.6	1.5	0.7	1.0	0.5	1.0	0.2	0.6	0.7	1.1	0.9	1.4	0.8	1.1
Standing height	0.7	7.0	28.8	-2.5	-4.2	-4.1	-2.6	-1.9	-2.1	-1.7	-0.8	-1.3	-2.2	0.1	-1.4	-1.8	-1.8	-2.7	-4.7	-1.1	-5.4
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	3.3	0.8	0.3	0.3	-1.6	-1.2	-1.0	-1.1	-1.5	-1.0	-1.4	-1.8	-1.0	-1.2	-0.4	0.3	-0.9	-1.2	0.0
Mood swings	0.7	1.2	3.5	1.2	1.3	1.3	1.2	0.0	1.5	0.9	1.2	0.8	1.3	0.9	0.7	1.0	1.1	-0.4	1.6	0.8	1.9
Osteoporosis (self-reported)	0.7	0.8	2.5	0.5	1.6	1.6	-0.3	0.3	0.1	-1.1	-0.6	-1.1	-0.6	-1.2	-1.1	-0.9	-1.0	-0.9	-0.3	-0.9	1.1
Average weekly champagne plus white wine intake	0.7	0.9	3.5	-1.1	-1.5	-1.5	0.4	-1.7	-1.1	-0.3	-0.1	0.3	-0.3	-0.2	-0.1	-0.0	1.0	1.1	-0.9	0.0	-1.9
Type 2 Diabetes (T2D) (2012)	0.6	0.7	6.9	-0.5	-0.3	-0.2	0.8	-0.4	0.2	0.6	0.4	0.4	0.4	0.6	0.4	0.4	1.5	2.6	0.6	0.3	-0.3
Blood Platelet Count	0.6	6.4	50.3	-1.2	-3.3	-3.4	1.2	-7.1	-1.6	2.0	1.2	1.8	1.1	3.5	1.5	1.4	1.6	1.0	1.4	1.7	-3.0
Heel T-Score	0.6	4.7	37.6	-3.2	-2.6	-2.6	-0.1	-6.1	-2.6	-0.1	-0.8	0.0	-0.9	-1.5	0.1	-0.4	1.4	1.3	-2.0	-0.1	-3.1
Allergy or Eczema	0.6	1.6	4.4	1.7	2.1	2.0	-1.1	0.5	0.1	-1.3	-1.1	-1.7	-1.1	-1.4	-1.2	-1.4	-1.4	-0.5	-0.3	-1.3	1.4
Hypothyroidism (self reported)	0.6	1.3	3.1	-0.6	-0.0	0.1	1.0	1.8	1.6	1.4	1.2	1.2	1.3	1.4	1.2	1.1	1.2	0.8	1.6	1.3	0.5
Hand grip strength (left)	0.6	1.5	7.6	-1.4	-2.1	-2.1	-0.6	-1.0	0.1	0.5	0.4	0.8	0.2	0.8	0.6	0.6	-0.1	-2.8	-0.9	0.7	-2.0
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	7.0	0.1	-0.4	-0.4	-1.2	-2.6	-0.9	-0.4	-0.7	-0.5	-0.6	-0.6	-0.4	-0.5	0.3	-0.9	-1.1	-0.6	-0.6
Qualifications: CSEs or equivalent	0.6	0.8	1.4	0.9	1.0	1.0	-1.1	-0.0	-0.5	-1.1	-0.8	-1.1	-1.0	-0.8	-1.2	-1.0	-1.2	-0.4	-0.4	-1.2	0.5
Hayfever, allergic rhinitis or eczema	0.6	1.3	4.7	1.7	2.2	2.1	-0.6	1.1	0.5	-1.0	-0.6	-1.2	-0.6	-1.1	-0.9	-0.9	-1.0	-0.5	0.4	-0.9	1.8
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.5	11.3	-1.5	-1.6	-1.7	-0.2	-3.4	-1.4	-0.3	0.0	-0.1	-0.5	-0.9	-0.2	-0.4	0.2	0.0	-1.4	-0.0	-1.8
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	3.2	-1.3	-1.3	-1.3	-0.0	-0.1	-0.3	0.3	-0.4	0.4	-0.1	0.2	0.4	0.2	1.8	1.5	-0.6	0.4	-1.4
Tense / ‘highly strung’	0.6	1.0	5.9	2.0	1.3	1.3	-0.5	2.4	0.4	-0.8	-0.9	-0.6	-0.6	-0.1	-0.7	-0.7	-0.5	0.6	0.1	-0.8	1.3
Worry too long after embarrassment	0.6	1.0	3.9	0.8	-0.0	-0.0	-1.3	-0.2	-1.2	-1.2	-0.8	-0.8	-0.9	-0.8	-0.9	-0.8	-1.7	-2.0	-1.4	-1.0	-0.4
Medication: Allopurinol	0.6	0.8	2.9	-0.3	0.4	0.4	1.3	1.7	0.7	0.6	1.4	0.7	1.0	1.0	0.6	0.7	0.3	1.1	1.1	0.8	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.5	-0.3	-0.2	-0.3	1.0	-0.4	0.4	1.1	1.1	0.9	1.2	0.8	1.0	1.1	1.0	-1.1	0.8	1.1	0.2
Alcohol intake frequency.	0.6	1.3	4.2	-1.7	-2.0	-2.0	0.0	-1.7	-1.3	0.4	0.5	0.4	-0.0	0.8	0.5	0.3	0.9	1.4	-0.8	0.5	-2.1
Illnesses of father: Heart disease	0.6	0.9	1.9	1.4	1.1	1.1	-0.6	0.5	-0.8	-0.9	-1.2	-1.1	-0.9	-0.6	-1.1	-1.2	-0.2	-1.2	-0.3	-1.1	0.8
Friendships satisfaction	0.6	0.8	2.4	1.5	1.0	1.0	-0.7	-1.1	-0.5	-0.9	-0.6	-1.1	-0.7	-1.5	-0.9	-0.8	-0.8	-0.3	-0.5	-0.9	0.8
Back pain experienced in last month	0.6	0.9	1.8	-0.9	0.1	0.1	0.9	0.6	1.3	1.0	0.5	1.2	1.2	0.8	1.2	1.2	1.0	1.1	1.0	1.2	0.7
Guilty feelings	0.6	0.8	2.8	-1.2	-0.3	-0.4	1.3	0.8	1.0	0.7	1.7	1.0	1.3	1.0	0.8	1.0	0.6	-0.8	0.6	1.0	0.0
Schizophrenia (2018)	0.5	1.1	3.9	-2.0	-0.8	-0.9	1.1	-0.1	0.5	1.2	1.1	1.3	1.2	1.0	1.3	1.2	0.6	0.4	0.8	1.3	-0.2
Reaction Time	0.5	1.0	2.6	0.7	0.4	0.4	-1.1	-0.5	-1.6	-1.3	-1.4	-1.1	-1.1	-0.7	-1.1	-1.1	-0.9	0.8	-1.5	-1.3	0.0
Body Mass Index (BMI) (2010)	0.5	0.6	2.0	-0.0	-0.2	-0.1	-1.3	-0.5	-1.4	-0.6	-0.7	-0.8	-0.9	-1.1	-0.6	-0.8	-0.7	-1.1	-1.3	-0.7	-0.4
BMI	0.5	2.9	6.8	-1.4	-1.3	-1.3	1.2	-1.4	0.8	2.6	1.7	2.3	2.1	1.8	2.4	2.3	1.9	0.6	1.8	2.3	-0.4
Medication: Co-codamol	0.5	0.6	3.5	-0.5	-0.5	-0.5	-0.9	-1.9	-0.8	-0.4	-0.5	-0.2	-0.4	-0.6	-0.3	-0.3	-0.3	-1.4	-1.1	-0.3	-0.5
Severe depression (siblings)	0.5	0.6	1.8	0.3	0.0	0.0	-0.6	0.0	-1.4	-1.0	-0.5	-0.9	-0.9	-0.4	-1.1	-1.1	0.2	1.2	-0.9	-1.0	-0.6
Relative age voice broke	0.5	0.8	2.8	1.5	1.6	1.7	-0.4	-0.6	0.4	-0.5	-0.7	-0.9	-0.6	-0.6	-0.8	-0.8	-0.3	0.4	0.5	-0.9	1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	8.6	-1.1	-1.3	-1.3	-0.0	-2.9	-1.3	-0.2	-0.2	-0.0	-0.4	-1.0	-0.2	-0.4	0.8	0.1	-1.0	-0.1	-1.5
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.8	1.3	0.5	0.5	-1.0	-0.8	-0.7	-0.4	-0.8	-1.0	-0.9	-1.0	-0.8	-0.9	0.6	-0.6	-0.0	-0.8	0.2
Medication: Atenolol	0.5	0.6	3.2	-0.4	0.0	0.1	1.2	0.6	1.1	0.6	0.6	0.6	0.8	0.5	0.7	0.8	0.8	1.8	1.0	0.7	0.2
Number of incorrect matches in round	0.5	0.8	3.3	-0.4	-0.9	-0.9	-1.0	0.7	-1.5	-0.9	-0.9	-0.8	-1.0	-0.3	-0.9	-0.9	-0.6	-0.2	-1.8	-0.7	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	3.9	1.4	1.2	1.2	0.4	0.9	1.1	0.2	0.2	0.2	0.4	-0.3	0.2	0.3	0.8	2.0	1.0	0.0	1.5
Fluid intelligence score	0.5	1.0	3.6	-1.5	-1.7	-1.7	0.8	1.1	-0.8	0.0	0.7	0.4	0.1	0.5	0.2	0.2	0.9	1.6	-0.5	0.2	-1.9
Father’s age at death	0.5	0.6	2.9	-0.5	-0.8	-0.8	-0.8	-1.7	-0.4	-0.7	-0.5	-0.6	-0.7	-0.9	-0.5	-0.6	-0.1	-0.0	-1.3	-0.4	-1.4
Arm fat mass (right)	0.5	2.3	5.4	-1.4	-1.4	-1.4	0.9	-0.9	0.6	2.3	1.5	2.1	1.6	1.8	2.1	1.9	1.7	-0.1	1.5	1.9	-0.8
Birth weight of first child	0.5	0.9	3.6	-1.9	-1.9	-1.8	-0.4	-0.9	-0.5	0.1	0.2	0.3	0.0	0.6	0.3	0.2	0.7	0.7	-1.1	0.5	-1.8
Health satisfaction	0.5	0.7	1.7	-0.6	-1.1	-1.1	0.5	-0.5	0.6	0.9	0.7	1.1	0.9	0.8	1.0	1.0	0.3	-1.3	0.3	0.9	-0.8
Emphysema/chronic bronchitis	0.5	0.6	2.7	0.9	1.6	1.6	0.4	0.7	0.7	-0.4	0.1	-0.3	0.2	-0.6	-0.3	-0.2	-0.2	-0.3	0.9	-0.1	1.6
Medication for pain relief, constipation, heartburn	0.5	0.9	2.2	1.2	0.5	0.5	-0.9	0.3	-0.4	-1.4	-0.8	-1.5	-1.2	-1.2	-1.4	-1.4	-0.6	-0.3	-1.0	-1.2	-0.1
Hypertension (Self-reported)	0.5	1.4	2.7	0.2	-0.3	-0.4	-1.5	-1.4	-1.2	-1.5	-1.5	-1.1	-1.6	-1.0	-1.4	-1.5	-1.3	0.7	-1.6	-1.4	-1.0
Handedness (chirality/laterality): Left-handed	0.5	0.5	2.9	-0.2	0.3	0.3	-0.0	0.8	1.0	0.8	0.2	0.6	0.6	1.1	0.7	0.8	-0.5	-1.7	0.8	0.5	0.8
Long-standing illness, disability or infirmity	0.5	0.7	2.4	1.2	1.5	1.5	-0.3	0.2	-0.4	-0.5	-1.0	-0.7	-0.4	-1.1	-0.6	-0.7	0.4	0.7	0.3	-0.7	1.5
Arm fat mass (left)	0.5	2.2	4.9	-1.6	-1.7	-1.7	0.9	-0.9	0.4	2.2	1.4	2.0	1.5	1.7	2.0	1.8	1.7	-0.0	1.2	1.9	-1.1
Eye problems/disorders: Glaucoma	0.5	0.6	2.3	0.8	1.3	1.3	0.3	-0.3	1.3	0.6	-0.1	0.4	0.5	0.1	0.4	0.4	0.0	-0.4	1.5	0.4	1.5
Pain type(s) experienced in last month: Hip pain	0.5	0.7	2.9	-1.6	-1.2	-1.3	0.4	-0.8	0.0	0.3	0.3	0.5	0.3	0.3	0.5	0.4	1.7	0.7	-0.4	0.5	-1.1
Age started oral contraceptive pill	0.5	0.7	1.7	1.2	1.0	1.0	-1.3	0.0	0.3	-0.8	-0.8	-1.2	-0.9	-0.8	-0.9	-0.9	-0.3	0.7	-0.4	-0.7	0.7
Crohns Disease (2017)	0.4	0.9	4.6	1.9	0.9	0.9	-1.2	-0.2	1.3	-0.4	-0.0	-0.6	-0.2	0.3	-0.3	-0.2	-1.8	-2.1	-0.0	-0.5	0.9
Breast Cancer	0.4	0.9	4.5	-0.3	-0.2	-0.3	0.9	1.1	1.0	0.8	0.6	1.0	0.9	0.8	0.9	0.8	1.5	2.1	1.0	0.9	0.2
Ovarian Cancer	0.4	0.6	1.5	1.2	0.6	0.6	-0.3	1.1	-0.5	-0.9	-0.7	-0.8	-0.8	-0.5	-0.8	-0.9	-0.7	1.2	-0.3	-0.8	0.5
Neuroticism (2016)	0.4	0.6	1.5	-0.8	-1.1	-1.1	0.8	-0.3	0.1	0.6	0.7	0.8	0.7	0.8	0.7	0.7	0.8	1.2	0.1	0.9	-0.8
Ulcerative Colitis	0.4	0.6	1.9	0.4	1.1	1.2	1.0	0.3	1.4	-0.2	1.3	-0.0	0.6	0.2	-0.2	-0.0	0.3	0.7	0.8	0.1	1.2
Average weekly spirits intake	0.4	0.6	2.0	-0.6	-1.0	-1.0	-0.2	-0.7	-1.4	-0.6	-0.2	-0.3	-0.6	-0.7	-0.4	-0.5	0.1	-0.5	-1.2	-0.5	-1.4
High blood pressure	0.4	1.1	2.1	0.0	-0.4	-0.4	-1.3	-1.3	-1.0	-1.4	-1.2	-1.0	-1.4	-0.8	-1.2	-1.3	-1.2	0.8	-1.4	-1.2	-1.0
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	1.5	1.2	1.2	1.2	-0.4	0.1	-0.1	-0.7	-0.6	-0.8	-0.6	-0.7	-0.8	-0.7	-1.0	-0.7	-0.2	-0.8	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.0	-0.6	-1.0	-1.0	0.1	-0.6	-0.3	0.9	0.7	0.7	0.6	0.8	0.8	0.8	0.6	-0.9	-0.1	0.7	-0.9
Peak expiratory flow (PEF)	0.4	1.0	3.6	-1.0	-1.1	-1.1	-1.2	-1.3	-0.8	-0.8	0.0	-0.6	-0.8	-0.4	-0.6	-0.8	-1.0	-1.1	-1.9	-0.5	-1.6
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.2	1.1	0.3	0.4	-0.8	-0.1	-1.0	-1.1	-0.4	-1.0	-0.9	-0.7	-1.0	-0.9	-0.5	-1.5	-0.7	-0.9	-0.1
Comparative body size at age 10	0.4	1.1	8.8	-1.0	-1.2	-1.2	-0.6	-3.0	0.2	0.9	-0.1	0.9	0.4	-0.1	0.9	0.8	-0.1	-1.7	-0.1	0.9	-0.8
Family relationship satisfaction	0.4	0.5	2.4	1.6	1.1	1.1	-0.4	-0.1	0.6	-0.4	-0.5	-0.6	-0.4	-0.6	-0.5	-0.4	-0.6	-0.1	0.3	-0.5	1.1
Commuting to job workplace: Car/motor vehicle	0.4	0.5	2.3	0.8	1.3	1.3	0.0	0.8	0.9	0.0	0.0	-0.2	0.2	-0.1	-0.2	-0.1	0.0	-0.3	0.9	-0.1	1.5
Hearing aid user	0.4	0.4	1.7	0.2	1.1	1.1	0.0	-0.0	0.7	-0.4	-0.6	-0.4	-0.4	-0.4	-0.5	-0.5	-0.3	1.3	0.4	-0.5	1.3
Financial situation satisfaction	0.4	0.5	2.7	1.3	1.0	1.0	0.0	1.6	1.0	-0.3	0.0	-0.3	-0.1	0.0	-0.4	-0.3	0.1	1.1	0.4	-0.3	1.0
Medication: Lisinopril	0.4	0.5	2.7	0.5	1.0	0.9	-0.7	-0.9	0.1	-0.2	-0.6	-0.4	-0.5	-0.9	-0.4	-0.4	-1.6	-0.3	0.0	-0.6	0.9
Illnesses of father: High blood pressure	0.4	0.4	2.1	1.5	1.0	1.0	-0.1	1.3	0.0	-0.2	-0.1	-0.3	-0.1	-0.0	-0.3	-0.3	-0.6	0.3	0.6	-0.5	1.0
Myopia	0.4	0.5	2.4	0.7	0.6	0.6	-0.8	-1.3	-0.9	-0.6	-0.4	-0.8	-0.5	-0.6	-0.6	-0.7	-0.1	-1.6	-0.6	-0.7	0.3
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.4	0.1	0.8	0.8	-0.6	-1.0	-1.2	-0.8	-0.7	-0.7	-0.6	-1.0	-0.8	-0.9	-0.7	-0.6	-0.8	-0.6	0.6
Depressed Affect (Nagel 2018)	0.3	0.6	1.5	0.5	0.6	0.6	1.2	0.2	1.0	0.5	1.0	0.6	0.9	0.7	0.5	0.7	1.2	0.7	1.2	0.6	1.0
Intelligence (Savage-Jansen 2018)	0.3	0.9	4.7	-1.5	-1.1	-1.1	1.1	2.2	0.1	0.2	0.7	0.5	0.3	0.5	0.4	0.3	0.3	1.7	0.1	0.4	-1.2
Irritable Bowel Disease (IBD)	0.3	0.8	2.2	1.4	1.4	1.5	-0.7	0.0	1.4	-0.7	0.3	-0.9	-0.2	-0.2	-0.7	-0.7	-1.2	-1.0	0.1	-0.6	1.2
Mean Putamen Volume	0.3	0.3	2.1	-0.6	-0.6	-0.7	-0.2	-1.3	0.2	0.4	0.4	0.1	0.2	0.0	0.4	0.3	0.0	-1.5	-0.1	0.3	-0.6
HDL Cholesterol	0.3	0.5	1.8	-1.1	-0.7	-0.6	-0.5	-1.1	-1.2	-0.6	-0.4	-0.6	-0.6	-0.4	-0.5	-0.6	0.2	-0.3	-1.3	-0.5	-1.1
Cardiovascular Disease	0.3	1.1	2.5	1.1	1.1	1.1	-0.9	0.1	-0.1	-1.4	-1.0	-1.2	-1.1	-0.5	-1.4	-1.4	-1.4	1.6	-0.5	-1.3	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.5	0.9	0.9	0.9	0.6	1.0	0.6	0.2	0.7	0.2	0.6	0.3	0.2	0.3	0.6	0.6	0.8	0.1	1.2
Medication: Levothyroxine sodium	0.3	0.6	1.2	-0.5	-0.1	-0.0	0.7	0.4	1.0	1.0	0.8	1.0	1.0	0.9	1.0	0.9	1.1	0.2	0.9	0.9	0.1
Financial difficulties in last 2 years	0.3	0.4	1.4	-0.0	-0.4	-0.4	0.8	0.9	1.0	0.4	0.4	0.7	0.6	0.7	0.6	0.5	0.4	1.2	0.3	0.6	-0.3
Heart attack	0.3	0.3	1.2	0.5	0.3	0.4	1.1	0.5	0.8	0.5	0.3	0.5	0.7	0.4	0.4	0.6	0.4	0.6	0.7	0.6	0.6
Illnesses of siblings	0.3	0.5	4.2	0.2	0.3	0.4	0.7	2.0	0.4	0.2	-0.5	0.3	0.1	0.1	0.1	0.1	0.3	1.7	0.8	0.1	0.6
Time employed in main current job	0.3	0.3	1.8	-0.2	-0.7	-0.8	0.7	-0.1	0.1	0.8	0.2	0.5	0.4	0.6	0.6	0.6	1.3	0.6	0.5	0.6	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.6	0.6	0.7	0.7	0.6	1.3	0.1	0.4	0.5	0.1	0.4	0.6	0.3	0.2	0.4	-0.4	1.1	0.1	0.9
Depression (self-reported)	0.3	0.3	1.1	1.0	0.8	0.8	0.2	0.2	0.6	0.3	0.5	0.2	0.5	0.9	0.2	0.3	0.5	-0.1	0.7	0.0	0.9
Length of working week for main job	0.3	0.3	1.5	0.2	-0.2	-0.2	0.4	-1.2	-0.1	0.5	0.5	0.6	0.5	0.4	0.6	0.5	-0.2	-1.1	0.5	0.5	-0.0
Glaucoma (self-reported)	0.3	0.4	1.5	0.8	1.2	1.2	0.1	0.0	0.7	0.1	-0.2	0.1	0.1	-0.1	0.0	0.0	0.0	-0.8	1.0	0.0	1.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	1.8	-0.0	0.6	0.6	0.4	1.0	1.4	1.0	0.5	0.8	0.9	0.7	0.9	0.7	1.1	0.8	1.2	0.9	0.9
High blood pressure (siblings)	0.3	0.5	1.6	-1.0	-1.1	-1.1	-0.1	-0.4	-0.0	-0.0	0.9	0.0	0.1	0.4	0.2	0.2	-0.5	-1.3	-0.8	0.2	-1.2
Eye problems/disorders: None of the above	0.3	0.4	2.4	0.4	-0.3	-0.3	-0.6	-0.7	-0.7	-0.3	-0.3	-0.4	-0.4	-0.2	-0.3	-0.4	-0.9	-1.5	-0.8	-0.3	-0.3
Medication: Ibuprofen	0.3	0.4	0.9	0.2	-0.5	-0.5	0.1	-0.5	0.4	1.0	0.7	0.7	0.7	0.8	0.9	0.9	0.9	-0.5	0.5	0.7	-0.3
Mean time to correctly identify matches	0.3	0.5	1.7	0.2	0.1	0.1	-0.8	-0.4	-1.3	-0.8	-1.0	-0.7	-0.8	-0.5	-0.7	-0.7	-0.4	0.9	-1.1	-1.0	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	3.4	-0.3	-0.7	-0.7	-0.4	1.5	0.6	-0.2	0.1	0.1	0.0	0.7	0.1	-0.0	-1.1	-1.9	-0.8	0.2	-0.7
Average weekly red wine intake	0.3	0.5	1.0	0.8	0.3	0.3	-1.0	-0.3	-0.4	-0.8	-0.8	-1.0	-0.9	-1.0	-0.8	-0.9	-0.2	0.2	-0.7	-0.9	0.2
Breast cancer (self-reported)	0.3	0.3	2.5	-0.9	0.0	0.1	0.0	-1.6	-1.1	-0.3	-0.6	-0.4	-0.4	-0.6	-0.3	-0.4	0.3	0.3	-0.7	-0.4	-0.1
Miserableness	0.3	0.5	1.8	0.9	0.9	0.9	1.1	-0.5	0.5	-0.0	0.8	0.2	0.7	0.2	0.2	0.4	1.0	1.4	0.7	0.3	1.0
Wears glasses or contact lenses	0.3	0.3	1.3	1.0	0.9	0.9	-0.4	-1.1	0.1	0.2	0.2	0.0	0.3	-0.0	0.1	0.2	-0.1	-1.1	0.2	-0.0	1.0
Ever depressed for a whole week	0.3	0.4	1.7	-0.3	-0.8	-0.8	0.3	1.0	-0.2	0.4	0.1	0.4	0.2	0.8	0.5	0.4	1.1	1.3	-0.2	0.4	-0.8
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.1	0.7	0.6	0.6	1.0	0.4	0.9	0.5	0.2	0.4	0.7	0.4	0.4	0.6	0.2	0.6	0.8	0.5	0.9
Pack years of smoking	0.3	0.4	0.9	0.4	0.4	0.3	0.8	-0.7	0.9	0.8	0.2	0.7	0.7	0.6	0.7	0.7	0.4	0.0	1.0	0.6	0.6
Ulcerative Colitis (UC)	0.2	0.3	1.4	0.4	1.1	1.2	0.3	0.0	1.1	-0.3	0.7	-0.4	0.2	-0.2	-0.4	-0.4	0.1	0.2	0.4	-0.2	0.9
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.8	-0.9	-0.9	-0.9	-0.4	0.8	-0.9	-0.6	-0.4	-0.6	-0.8	-0.3	-0.6	-0.6	-0.5	-0.3	-1.0	-0.6	-1.3
Prostate Cancer	0.2	0.3	1.7	0.1	1.0	1.0	0.1	1.3	0.4	-0.3	-0.1	-0.6	0.0	-0.2	-0.3	-0.2	0.4	-0.2	0.2	-0.3	1.0
Lung FEV1/FVC ratio	0.2	0.8	3.0	0.3	0.7	0.7	-1.3	-1.7	-0.3	-0.4	-0.8	-0.9	-0.8	-0.8	-0.5	-0.8	-1.3	-1.4	-0.8	-0.8	0.5
Angina	0.2	0.3	1.1	0.6	0.9	0.9	0.3	-0.3	0.3	-0.3	-0.6	-0.2	-0.2	-0.5	-0.4	-0.2	0.5	0.8	0.4	-0.2	1.0
Pack years adult smoking proportion	0.2	0.4	1.0	0.4	0.2	0.2	0.8	-0.5	0.9	0.8	0.2	0.7	0.7	0.7	0.7	0.8	0.6	0.4	1.0	0.6	0.5
Taking other prescription medications	0.2	0.3	0.8	0.8	0.9	0.9	-0.7	0.2	-0.2	-0.4	-0.8	-0.5	-0.4	-0.4	-0.5	-0.5	0.1	0.3	0.0	-0.5	0.8
High blood pressure (mother)	0.2	0.3	1.1	0.8	0.7	0.7	-0.7	-1.1	0.5	-0.3	-0.4	-0.6	-0.4	-0.8	-0.5	-0.5	-0.3	-0.4	-0.1	-0.5	0.7
Body mass index (BMI)	0.2	1.0	2.9	-0.2	-0.2	-0.2	0.5	-1.1	0.4	1.7	0.8	1.4	1.1	0.9	1.4	1.3	1.1	0.1	1.5	1.2	0.4
Nervous feelings	0.2	0.3	2.0	1.0	0.4	0.4	-0.7	-0.1	-0.2	-0.5	-0.7	-0.5	-0.5	-0.1	-0.6	-0.4	-0.2	-1.4	-0.4	-0.4	0.1
Neuroticism score	0.2	0.5	1.5	1.1	0.9	0.9	0.9	0.9	0.6	-0.0	0.6	0.3	0.6	0.6	0.1	0.4	1.2	0.3	0.8	0.1	1.0
Weight	0.2	1.1	3.7	-1.1	-1.9	-1.9	-0.8	-1.9	-0.6	0.8	0.3	0.6	0.1	0.7	0.6	0.4	0.3	-1.2	-0.6	0.6	-1.9
Medication: Lansoprazole	0.2	0.3	0.9	-0.7	-0.3	-0.4	0.8	-0.5	0.2	0.3	0.9	0.4	0.5	0.5	0.5	0.4	0.7	1.0	0.4	0.5	-0.0
Pulse wave reflection index	0.2	0.2	1.6	0.4	0.4	0.4	0.2	1.3	-0.2	-0.1	0.0	-0.1	0.1	-0.3	-0.1	-0.1	0.7	0.8	0.3	0.1	0.3
Blood clot in the leg (DVT)	0.2	0.3	1.3	-0.1	0.6	0.6	-0.5	-1.1	-0.7	-0.4	-0.3	-0.4	-0.2	-0.6	-0.5	-0.5	-0.5	-0.8	-0.6	-0.3	0.5
Medication: Paracetamol	0.2	0.3	2.0	-1.4	-0.1	-0.1	-0.2	-0.0	0.0	0.6	-0.3	0.8	0.4	0.6	0.7	0.7	-0.2	-0.4	0.2	0.6	0.3
Headache pain in last month	0.2	0.4	1.2	-0.8	-0.5	-0.4	0.3	-0.4	-0.1	0.8	0.1	0.8	0.5	0.7	0.7	0.6	0.9	1.1	0.5	0.5	-0.1
Medication: Amlodipine	0.2	0.3	1.8	0.9	0.1	0.1	-0.6	-1.4	0.5	-0.2	-0.7	0.0	-0.2	-0.1	-0.1	-0.1	0.1	0.9	-0.3	-0.2	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.4	1.2	1.0	1.0	-0.1	0.5	0.6	0.1	0.0	-0.1	0.1	0.5	-0.0	-0.1	0.5	0.1	0.6	0.0	1.0
Medication: Blood pressure	0.2	0.4	3.0	-0.3	-0.3	-0.3	-0.2	-1.2	-0.6	-0.3	-0.8	-0.2	-0.5	-0.6	-0.3	-0.4	-0.3	1.7	-0.5	-0.4	-0.5
Overall health rating	0.2	0.4	1.8	0.4	1.3	1.2	0.3	0.2	0.8	0.1	0.6	0.1	0.6	0.3	0.0	0.2	0.4	0.4	0.7	-0.0	1.3
Age at last live birth	0.2	0.3	4.7	-0.3	-0.3	-0.4	-0.3	0.5	0.6	0.0	-0.3	0.3	0.0	-0.0	0.2	0.2	-0.4	-2.2	-0.3	0.4	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.0	0.8	0.5	0.5	-0.5	-0.2	0.1	-0.8	-0.1	-0.7	-0.5	-0.2	-0.6	-0.7	-1.0	0.1	-0.4	-0.7	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	1.1	-0.7	-1.0	-1.0	0.2	0.5	0.0	0.4	0.2	0.5	0.2	0.1	0.6	0.4	0.5	-0.3	-0.2	0.5	-0.9
Loneliness, isolation	0.2	0.3	1.3	1.1	0.9	0.9	0.1	-0.7	-0.0	-0.2	-0.4	-0.3	-0.2	-0.5	-0.4	-0.3	0.7	0.6	0.3	-0.4	0.7
Illnesses of father: None of the above (group 1)	0.2	0.3	1.1	-0.9	-0.4	-0.4	-0.8	-1.1	0.0	-0.5	-0.5	-0.2	-0.3	-0.4	-0.2	-0.1	-0.7	0.4	-1.0	-0.1	-0.5
Number of self-reported non-cancer illnesses	0.2	0.4	1.5	0.4	0.9	0.9	-0.5	-0.7	-0.4	-0.7	-0.6	-0.6	-0.5	-0.6	-0.7	-0.7	-0.1	1.2	-0.2	-0.6	0.7
Commuting to job workplace: Public transport	0.2	0.3	1.3	0.5	-0.3	-0.2	-0.4	-1.0	-1.0	0.0	-0.5	-0.0	-0.4	-0.6	-0.1	-0.2	1.1	-0.1	-0.3	-0.1	-0.2
Medication: Blood pressure	0.2	0.5	1.5	-0.5	-0.8	-0.9	-1.1	-0.9	-0.5	-0.6	-0.6	-0.2	-0.8	-0.0	-0.4	-0.3	-1.0	-0.0	-1.0	-0.4	-1.2
Medication: Bendroflumethiazide	0.2	0.3	1.8	-0.2	0.2	0.2	0.1	0.3	0.7	-0.1	0.4	0.1	0.1	0.7	0.1	0.2	-1.3	1.3	0.2	0.1	0.1
Medication: Paracetamol	0.2	0.3	1.4	-1.2	0.1	0.1	-0.3	0.7	0.3	0.7	-0.3	0.7	0.5	0.5	0.8	0.7	0.0	-0.2	0.4	0.6	0.4
Number of operations (self-reported)	0.2	0.2	0.8	-0.2	-0.7	-0.7	-0.1	0.4	-0.9	-0.3	-0.4	-0.1	-0.4	-0.1	-0.3	-0.3	-0.1	-0.6	-0.9	-0.2	-0.9
Diastolic blood pressure, automated reading	0.2	0.5	1.3	0.8	0.3	0.3	-0.5	-0.2	-1.2	-0.7	-1.0	-0.7	-0.9	-0.9	-0.9	-0.8	-0.8	-0.5	-0.6	-1.0	-0.0
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.8	0.2	0.3	0.3	0.9	1.4	0.6	0.9	1.1	0.6	1.0	0.6	0.8	0.8	0.7	-1.4	0.9	0.8	0.6
Neuroticism (Nagel 2018)	0.1	0.2	0.8	0.2	-0.2	-0.3	0.6	0.4	0.4	0.2	0.8	0.4	0.5	0.7	0.3	0.4	0.7	-0.9	0.4	0.4	-0.1
Worry (Nagel 2018)	0.1	0.2	1.2	0.6	0.1	0.1	-0.5	1.0	0.1	-0.4	-0.6	-0.3	-0.4	0.5	-0.3	-0.2	-0.4	-1.1	-0.2	-0.4	-0.1
Alzheimer’s Disease (in father)	0.1	0.1	0.8	0.0	-0.6	-0.6	0.1	0.1	-0.0	0.3	0.4	0.1	0.1	-0.1	0.2	0.1	-0.3	-0.9	-0.1	0.1	-0.8
Crohns Disease (2012)	0.1	0.2	1.7	0.9	-0.3	-0.3	-0.5	0.1	0.4	-0.4	0.1	-0.3	-0.3	0.1	-0.2	-0.3	-1.3	-0.5	-0.4	-0.4	-0.3
Schizophrenia (2014)	0.1	0.1	1.0	-0.8	-0.4	-0.5	0.2	-1.0	-0.4	0.3	-0.2	0.3	0.1	-0.1	0.2	0.2	-0.1	-0.2	-0.1	0.1	-0.1
Blood White Count	0.1	0.4	1.6	0.0	0.4	0.4	-0.3	-1.3	0.6	0.7	0.7	0.2	0.7	0.6	0.4	0.5	0.9	-0.6	0.6	0.6	0.6
Hair Pigment	0.1	3.9	12.7	-0.1	0.8	0.8	2.0	1.9	3.6	2.0	1.5	2.3	2.1	1.3	2.1	2.1	1.5	2.5	3.3	1.9	1.8
Number of treatments/medications taken	0.1	0.2	2.0	-0.4	0.1	0.1	-0.3	-1.4	0.3	0.3	-0.0	0.3	0.2	0.3	0.3	0.3	0.4	0.6	0.2	0.3	0.1
Average weekly fortified wine intake	0.1	0.2	0.7	-0.6	-0.4	-0.4	-0.5	0.4	-0.3	-0.0	0.2	-0.3	-0.2	-0.2	-0.2	-0.2	-0.5	-0.8	-0.6	-0.1	-0.4
Age when periods started (menarche)	0.1	0.2	1.9	-0.3	-0.2	-0.1	-0.7	0.1	0.6	-0.2	0.4	-0.1	0.0	0.7	-0.0	0.0	-1.4	-0.7	-0.5	0.1	-0.3
Stomach or abdominal pain in last month	0.1	0.1	0.3	-0.4	0.0	-0.0	-0.5	-0.5	0.1	0.5	0.1	0.2	0.3	-0.0	0.6	0.4	0.1	0.3	0.3	0.4	0.3
Chronic bronchitis/emphysema (father)	0.1	0.1	0.5	0.4	0.5	0.5	0.4	0.6	-0.1	-0.0	0.3	-0.0	0.1	0.0	0.0	0.0	0.4	0.1	0.5	0.1	0.7
Had other major operations	0.1	0.2	0.7	0.8	0.5	0.6	0.6	0.6	0.4	0.1	-0.1	0.2	0.3	-0.2	0.0	0.2	0.6	0.1	0.3	0.1	0.7
Hip circumference	0.1	0.6	2.4	-0.3	-1.2	-1.3	-1.0	-1.5	-0.8	0.5	-0.3	0.2	-0.3	0.4	0.2	0.0	0.2	-1.0	-0.4	0.2	-1.4
Lung cancer (father)	0.1	0.1	0.3	-0.5	-0.3	-0.4	-0.1	-0.2	0.0	-0.2	-0.3	-0.3	-0.3	-0.1	-0.2	-0.2	-0.4	0.3	-0.3	-0.0	-0.4
Wheeze or whistling in the chest in last year	0.1	0.1	1.9	0.1	-0.1	-0.0	0.1	-0.3	-0.5	-0.2	-0.0	0.0	-0.0	-0.3	-0.0	0.0	0.4	1.4	-0.1	-0.0	-0.1
Angina (self-reported)	0.1	0.2	0.6	0.3	0.7	0.7	0.4	0.0	0.4	-0.3	-0.5	-0.1	-0.1	-0.4	-0.3	-0.1	0.5	0.7	0.4	-0.1	0.8
Migraine (self-reported)	0.1	0.2	0.7	0.0	0.4	0.4	0.5	0.4	0.3	0.2	0.5	0.3	0.5	0.3	0.2	0.4	0.8	0.1	0.7	0.1	0.7
Had major operations	0.1	0.1	0.4	-0.5	-0.2	-0.2	-0.3	0.2	-0.1	-0.1	-0.4	-0.1	-0.4	0.0	-0.0	-0.2	-0.2	0.7	-0.3	-0.2	-0.2
Medication for cholesterol	0.1	0.1	0.3	-0.3	-0.2	-0.2	0.5	-0.4	-0.3	0.5	0.3	0.3	0.4	-0.2	0.4	0.4	0.4	-0.4	0.1	0.4	0.0
Medication: Aspirin	0.1	0.2	0.6	-0.2	-0.0	-0.0	0.6	0.3	0.4	0.4	0.4	0.5	0.4	0.5	0.4	0.5	-0.2	0.0	0.7	0.4	0.2
Alcohol drinker status: Never	0.1	0.2	0.6	-0.1	-0.7	-0.7	0.0	-0.5	-0.6	0.2	0.0	0.2	0.0	0.2	0.3	0.2	0.6	0.8	-0.1	0.2	-0.6
Supplements: Calcium	0.1	0.2	0.8	-0.5	0.1	0.1	0.8	0.6	0.6	-0.1	0.9	0.1	0.5	-0.0	0.2	0.2	-0.3	0.2	-0.0	0.0	0.1
Neuroticism	0.0	0.1	0.3	0.5	0.1	0.1	-0.2	0.1	-0.3	-0.5	-0.2	-0.3	-0.2	0.3	-0.4	-0.3	0.1	-0.2	-0.3	-0.4	0.0
Tanning	0.0	0.6	2.8	-0.6	-1.1	-1.1	1.1	0.4	0.1	0.1	0.1	0.6	0.2	-0.0	0.3	0.2	1.6	1.7	-0.1	0.5	-0.9
Medication: Aspirin	0.0	0.1	0.4	0.0	0.2	0.2	0.2	0.3	0.2	0.2	-0.1	0.2	0.1	0.1	0.2	0.1	-0.3	-0.0	0.6	0.1	0.3
Risk taking	0.0	0.1	0.3	-0.6	-0.1	-0.0	-0.4	0.1	0.1	0.1	-0.5	0.1	-0.2	-0.3	0.1	-0.1	0.3	0.2	-0.0	-0.1	0.1

Hub : Genes

MTFR1L

Models

Trait associations