Best TWAS P=1.05e-08 · Best GWAS P=3.02e-10 conditioned to 3.75e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | PDE8B | 0.09 | 0.03 | enet | 17 | 0.05 | 2.9e-08 | 5.9 | 5.7 | 1.0e-08 | -0.05 | 0.02 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | AP3B1 | 0.02 | 0.00 | blup | 126 | 0.01 | 1.8e-02 | 5.7 | 5.3 | 9.2e-08 | -0.03 | 0.02 | 0.87 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LOC728723 | 0.12 | 0.04 | enet | 19 | 0.04 | 1.3e-05 | 6.0 | 5.5 | 3.1e-08 | 0.09 | 0.00 | 0.99 | TRUE |