Best TWAS P=4.4e-10 · Best GWAS P=9.4e-09 conditioned to 0.431
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | WBP1L | 0.05 | 0.00 | enet | 8 | 0.00 | 5.3e-01 | -4.9 | 5.3 | 9.0e-08 | 0.38 | 0.08 | 0.32 | FALSE |
| 2 | GTEx | Artery Aorta | TMEM180 | 0.25 | 0.23 | enet | 37 | 0.25 | 7.4e-14 | -4.4 | -5.3 | 1.2e-07 | -0.54 | 0.76 | 0.22 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | TRIM8 | 0.09 | 0.03 | enet | 25 | 0.06 | 3.7e-08 | 5.3 | 6.2 | 4.4e-10 | 0.85 | 0.01 | 0.99 | TRUE |