TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Waist Hip Ratio (WHR)
:
←
→
chr10:103,527,782-105,275,242
Best TWAS P=4.4e-10 · Best GWAS P=9.4e-09 conditioned to 0.431
103.6M
103.8M
104M
104.2M
104.4M
104.6M
104.8M
105M
105.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
ROSMAP
Brain Pre-frontal Cortex
TRIM8
0.09
0.03
enet
25
0.06
3.7e-08
5.3
6.2
4.4e-10
0.85
0.01
0.99
TRUE
1
GTEx
Adipose Subcutaneous
WBP1L
0.05
0.00
enet
8
0.00
5.3e-01
-4.9
5.3
9.0e-08
0.38
0.08
0.32
FALSE
2
GTEx
Artery Aorta
TMEM180
0.25
0.23
enet
37
0.25
7.4e-14
-4.4
-5.3
1.2e-07
-0.54
0.76
0.22
FALSE