[Hub]/) : Traits : Ulcerative Colitis :

chr2:218,382,236-219,846,749

Best TWAS P=1.05e-08 · Best GWAS P=2.03e-07 conditioned to 0.208

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous TMBIM1 0.12 0.08 lasso 5 0.10 2.9e-08 5.2 -5.1 3.0e-07 -0.94 0.02 0.98 FALSE
2 GTEx Adipose Visceral Omentum RP11-378A13.1 0.30 0.28 enet 30 0.32 2.9e-17 4.5 -5.1 3.0e-07 -0.90 0.07 0.93 FALSE
3 GTEx Artery Aorta TMBIM1 0.17 0.20 enet 29 0.19 1.2e-10 5.0 -5.1 2.7e-07 -0.93 0.05 0.95 FALSE
4 GTEx Breast Mammary Tissue (Female) ARPC2 0.12 -0.01 lasso 5 -0.01 7.1e-01 5.1 -5.2 1.7e-07 -0.87 0.06 0.37 FALSE
5 GTEx Breast Mammary Tissue (Female) RP11-378A13.1 0.30 0.11 lasso 10 0.22 3.0e-07 5.2 -5.2 2.3e-07 -0.98 0.03 0.97 FALSE
6 GTEx Cells EBV-transformed lymphocytes TMBIM1 0.35 0.24 lasso 10 0.24 2.3e-08 5.1 -5.3 1.1e-07 -0.98 0.02 0.98 FALSE
7 GTEx Cells EBV-transformed lymphocytes RP11-378A13.1 0.18 0.14 lasso 6 0.13 4.6e-05 5.1 -5.1 2.8e-07 -0.97 0.03 0.93 FALSE
8 GTEx Cells Transformed fibroblasts TMBIM1 0.15 0.25 lasso 3 0.27 2.2e-20 5.0 -5.2 1.7e-07 -0.97 0.03 0.97 FALSE
9 GTEx Testis RP11-378A13.1 0.37 0.18 enet 22 0.22 2.7e-10 5.1 -5.2 1.9e-07 -0.96 0.02 0.98 FALSE
10 GTEx Thyroid ARPC2 0.10 0.03 enet 8 0.04 3.0e-04 5.0 -5.4 6.4e-08 -0.87 0.03 0.95 FALSE
11 METSIM Adipose AAMP 0.03 0.00 bslmm 433 0.01 7.1e-03 5.1 -5.7 1.0e-08 -0.77 0.05 0.87 TRUE
12 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma TMBIM1 0.10 0.04 blup 49 0.06 3.0e-03 5.0 -5.2 1.5e-07 -0.97 0.02 0.81 FALSE
13 The Cancer Genome Atlas Soft Tissue Sarcoma TMBIM1 0.07 0.04 blup 49 0.03 4.8e-03 4.1 -5.1 3.0e-07 -0.93 0.03 0.63 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma TMBIM1 0.02 0.02 blup 49 0.02 9.3e-03 5.0 -5.1 2.9e-07 -0.98 0.01 0.78 FALSE