[Hub]/) : Traits : Verbal and Numeric Reasoning (VNR) :

chr3:23,234,618-24,686,628

Best TWAS P=5.79e-11 · Best GWAS P=2.49e-15 conditioned to 0.513

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 ROSMAP Brain Pre-frontal Cortex NKIRAS1 0.10 0.07 enet 16 0.07 2.5e-09 -4.6 -6.1 1.1e-09 0.66 0.97 0.03 FALSE
2 YFS Blood NKIRAS1 0.02 0.02 lasso 2 0.02 1.4e-06 4.8 -5.2 1.6e-07 0.53 0.31 0.67 TRUE
3 The Cancer Genome Atlas Breast Invasive Carcinoma NKIRAS1 0.02 0.01 blup 60 0.01 6.9e-04 3.1 -5.7 1.0e-08 0.66 0.10 0.12 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma RPL15 0.04 0.02 blup 44 0.02 2.1e-04 -6.5 -5.7 1.2e-08 0.68 0.25 0.56 FALSE
5 The Cancer Genome Atlas Brain Lower Grade Glioma NKIRAS1 0.14 0.05 blup 60 0.06 7.0e-07 -5.5 -6.3 4.1e-10 0.74 0.40 0.59 FALSE
6 The Cancer Genome Atlas Lung Squamous Cell Carcinoma NR1D2 0.03 0.02 enet 4 0.04 5.5e-05 -7.3 -6.5 5.8e-11 0.74 0.01 0.93 TRUE
7 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma NR1D2 0.08 0.01 enet 6 0.02 1.2e-02 -5.9 -6.5 9.7e-11 0.80 0.01 0.91 FALSE
8 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RPL15 0.14 0.06 lasso 4 0.05 1.8e-04 -5.8 -6.4 1.6e-10 0.72 0.05 0.82 FALSE
9 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma UBE2E1 0.08 0.03 lasso 2 0.03 2.3e-03 -6.2 -6.3 3.2e-10 0.73 0.03 0.77 FALSE