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chr3:23,234,618-24,686,628

Best TWAS P=5.79e-11 · Best GWAS P=2.49e-15 conditioned to 0.513

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	NR1D2	0.03	0.02	enet	4	0.04	5.5e-05	-7.3	-6.5	5.8e-11	0.74	0.01	0.93	TRUE
2	YFS	Blood	NKIRAS1	0.02	0.02	lasso	2	0.02	1.4e-06	4.8	-5.2	1.6e-07	0.53	0.31	0.67	TRUE
7	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	NR1D2	0.08	0.01	enet	6	0.02	1.2e-02	-5.9	-6.5	9.7e-11	0.80	0.01	0.91	FALSE
8	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RPL15	0.14	0.06	lasso	4	0.05	1.8e-04	-5.8	-6.4	1.6e-10	0.72	0.05	0.82	FALSE
9	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	UBE2E1	0.08	0.03	lasso	2	0.03	2.3e-03	-6.2	-6.3	3.2e-10	0.73	0.03	0.77	FALSE
5	The Cancer Genome Atlas	Brain Lower Grade Glioma	NKIRAS1	0.14	0.05	blup	60	0.06	7.0e-07	-5.5	-6.3	4.1e-10	0.74	0.40	0.59	FALSE
1	ROSMAP	Brain Pre-frontal Cortex	NKIRAS1	0.10	0.07	enet	16	0.07	2.5e-09	-4.6	-6.1	1.1e-09	0.66	0.97	0.03	FALSE
3	The Cancer Genome Atlas	Breast Invasive Carcinoma	NKIRAS1	0.02	0.01	blup	60	0.01	6.9e-04	3.1	-5.7	1.0e-08	0.66	0.10	0.12	FALSE
4	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPL15	0.04	0.02	blup	44	0.02	2.1e-04	-6.5	-5.7	1.2e-08	0.68	0.25	0.56	FALSE