[Hub]/) : Traits : Blood White Count :

chr5:147,012,186-148,894,875

Best TWAS P=2.01e-14 · Best GWAS P=8.98e-20 conditioned to 1.02e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FBXO38 0.05 0.01 blup 489 0.02 1.5e-03 -7.2 6.5 9.5e-11 0.04 0.79 0.01 FALSE
2 CommonMind Brain Pre-frontal Cortex HTR4 0.06 0.03 lasso 4 0.03 4.3e-05 -5.6 -6.9 4.1e-12 -0.02 0.66 0.01 FALSE
3 ROSMAP Brain Pre-frontal Cortex SPINK9 0.08 0.07 enet 21 0.07 1.4e-09 -6.2 -6.0 2.3e-09 -0.03 1.00 0.00 FALSE
4 YFS Blood ADRB2 0.09 0.05 bslmm 455 0.05 2.4e-15 8.7 6.4 1.4e-10 0.83 0.03 0.97 FALSE
5 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FBXO38 0.04 0.04 blup 52 0.04 4.8e-03 -6.8 7.0 1.8e-12 0.05 0.02 0.68 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma ADRB2 0.08 0.00 blup 55 0.01 7.7e-02 -4.2 -7.2 7.2e-13 -0.59 0.01 0.48 TRUE
7 The Cancer Genome Atlas Colon Adenocarcinoma FBXO38 0.05 0.02 lasso 2 0.02 4.3e-02 -6.1 6.3 2.3e-10 0.03 0.04 0.31 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FBXO38 0.02 0.03 enet 2 0.03 1.9e-04 4.2 5.6 2.2e-08 0.04 0.04 0.56 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma FBXO38 0.11 0.02 blup 52 0.04 8.2e-06 -7.1 5.9 2.8e-09 0.06 0.02 0.98 FALSE
10 The Cancer Genome Atlas Lung Adenocarcinoma FBXO38 0.03 0.02 blup 51 0.02 7.7e-04 -6.2 7.0 2.2e-12 0.03 0.10 0.82 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma FBXO38 0.05 0.01 blup 51 0.02 7.9e-03 3.3 7.7 2.0e-14 0.03 0.03 0.48 TRUE
12 The Cancer Genome Atlas Rectum Adenocarcinoma FBXO38 0.13 0.17 enet 16 0.15 2.3e-04 -7.2 7.2 4.5e-13 0.05 0.02 0.91 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma FBXO38 0.06 0.01 enet 7 0.01 3.2e-02 1.4 6.0 1.7e-09 0.04 0.03 0.43 FALSE