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chr6:87,167,376-88,919,551

Best TWAS P=1.18e-21 · Best GWAS P=2.74e-20 conditioned to 0.103

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C6orf164	0.06	0.01	blup	430	0.03	4.2e-05	-5.51	-5.3	9.5e-08	0.33	0.76	0.12	FALSE
2	CommonMind	Brain Pre-frontal Cortex	ZNF292	0.04	0.05	lasso	12	0.03	4.1e-05	-9.11	9.3	2.0e-20	-1.00	0.03	0.97	FALSE
3	GTEx	Adipose Subcutaneous	SMIM8	0.10	0.02	lasso	5	0.02	1.7e-02	-8.18	7.4	1.9e-13	-0.61	0.38	0.07	FALSE
4	GTEx	Adipose Visceral Omentum	C6orf163	0.17	0.14	lasso	9	0.17	2.8e-09	-8.16	-6.7	2.6e-11	0.53	0.85	0.14	FALSE
5	GTEx	Artery Aorta	RP11-393I2.4	0.10	0.03	lasso	5	0.02	2.4e-02	-8.85	9.0	1.8e-19	-0.84	0.10	0.82	FALSE
6	GTEx	Artery Coronary	C6orf163	0.27	0.05	lasso	4	0.02	5.9e-02	-8.16	-6.2	4.8e-10	0.65	0.11	0.12	FALSE
7	GTEx	Artery Tibial	C6orf163	0.12	0.08	lasso	2	0.07	7.5e-06	-8.79	-8.5	1.5e-17	0.77	0.20	0.78	FALSE
8	GTEx	Brain Cortex	SMIM8	0.43	0.24	enet	44	0.34	4.6e-10	-4.67	-5.3	1.4e-07	0.71	0.11	0.88	FALSE
9	GTEx	Breast Mammary Tissue	C6orf163	0.13	0.10	lasso	12	0.09	1.5e-05	-8.76	-8.1	3.7e-16	0.71	0.53	0.46	FALSE
10	GTEx	Breast Mammary Tissue (Male)	C6orf163	0.09	0.00	enet	4	0.01	2.2e-01	-8.41	-7.0	2.1e-12	0.61	0.07	0.19	FALSE
11	GTEx	Breast Mammary Tissue (Female)	C6orf163	0.21	0.00	lasso	4	0.03	5.3e-02	-4.07	-7.2	6.4e-13	0.59	0.06	0.17	FALSE
12	GTEx	Cells EBV-transformed lymphocytes	C6orf163	0.18	0.14	lasso	4	0.15	1.5e-05	-8.19	-8.5	1.6e-17	0.78	0.29	0.58	FALSE
13	GTEx	Cells Transformed fibroblasts	SMIM8	0.18	0.14	lasso	5	0.12	1.4e-09	-8.19	8.2	2.3e-16	-0.74	0.98	0.02	FALSE
14	GTEx	Cells Transformed fibroblasts	C6orf163	0.16	0.14	lasso	3	0.18	2.7e-13	-8.16	-8.5	1.8e-17	0.74	0.60	0.40	FALSE
15	GTEx	Colon Sigmoid	RP11-393I2.4	0.14	0.02	enet	27	0.07	2.0e-03	-8.85	5.8	8.8e-09	-0.60	0.04	0.79	FALSE
16	GTEx	Esophagus Muscularis	C6orf163	0.08	0.07	lasso	4	0.07	6.4e-05	-8.23	-6.9	4.7e-12	0.57	0.58	0.19	FALSE
17	GTEx	Lung	C6orf163	0.07	0.08	enet	7	0.09	2.8e-07	-8.16	-6.8	8.0e-12	0.55	0.65	0.23	FALSE
18	GTEx	Lung	RP11-393I2.4	0.09	0.06	lasso	2	0.04	8.4e-04	-8.85	8.9	7.5e-19	-0.82	0.30	0.64	FALSE
19	GTEx	Muscle Skeletal	C6orf163	0.07	0.02	enet	32	0.04	5.5e-05	-8.47	-7.0	1.9e-12	0.53	0.12	0.87	FALSE
20	GTEx	Nerve Tibial	SMIM8	0.22	0.10	lasso	8	0.16	3.8e-11	-8.23	5.5	3.7e-08	-0.41	0.98	0.02	FALSE
21	GTEx	Nerve Tibial	ZNF292	0.09	0.07	enet	16	0.10	1.5e-07	8.60	9.6	1.2e-21	-0.89	0.09	0.91	TRUE
22	GTEx	Nerve Tibial	C6orf163	0.12	0.06	enet	10	0.11	2.5e-08	-8.23	-5.6	1.7e-08	0.38	0.91	0.07	FALSE
23	GTEx	Nerve Tibial	RP11-393I2.4	0.08	0.09	enet	18	0.09	6.8e-07	-8.41	9.2	4.5e-20	-0.84	0.22	0.78	FALSE
24	GTEx	Pituitary	RP11-393I2.4	0.39	0.10	lasso	12	0.10	1.6e-03	-5.40	8.0	9.6e-16	-0.70	0.09	0.37	FALSE
25	GTEx	Stomach	C6orf163	0.10	0.06	lasso	1	0.05	2.3e-03	-8.18	-8.2	2.8e-16	0.74	0.30	0.18	FALSE
26	GTEx	Thyroid	C6orf163	0.21	0.08	enet	32	0.14	6.6e-11	-8.23	-5.5	2.9e-08	0.37	0.85	0.15	FALSE
27	GTEx	Vagina	C6orf163	0.28	0.13	enet	28	0.18	5.7e-05	-8.23	-5.8	8.0e-09	0.59	0.19	0.36	FALSE
28	GTEx	Whole Blood	C6orf163	0.09	0.04	enet	14	0.02	6.4e-03	-0.68	-5.6	2.5e-08	0.16	0.12	0.14	FALSE
29	METSIM	Adipose	C6orf164	0.05	0.06	lasso	8	0.06	9.3e-10	-8.12	-8.4	5.6e-17	0.79	0.87	0.13	FALSE
30	METSIM	Adipose	C6ORF165	0.03	0.04	lasso	4	0.03	7.7e-06	-5.25	-5.6	2.3e-08	0.54	0.95	0.04	FALSE
31	NTR	Blood	C6orf162	0.02	0.02	blup	411	0.02	1.7e-08	8.62	-8.0	1.3e-15	0.86	0.09	0.91	FALSE
32	NTR	Blood	SLC35A1	0.02	0.00	bslmm	474	0.01	1.4e-03	-8.49	6.7	1.5e-11	-0.45	0.29	0.27	FALSE
33	ROSMAP	Brain Pre-frontal Cortex	SMIM8	0.21	0.33	enet	34	0.38	3.9e-52	8.51	-7.2	6.6e-13	0.81	0.32	0.68	FALSE
34	ROSMAP	Brain Pre-frontal Cortex	SLC35A1	0.30	0.48	enet	25	0.50	5.7e-73	6.81	6.9	6.7e-12	-0.64	1.00	0.00	FALSE
35	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C6orf162	0.09	0.01	enet	12	0.03	2.5e-03	-8.22	5.3	1.0e-07	-0.31	0.26	0.13	FALSE
36	The Cancer Genome Atlas	Breast Invasive Carcinoma	C6orf164	0.06	0.05	blup	94	0.06	1.0e-11	8.99	-8.1	5.9e-16	0.84	0.03	0.97	FALSE
37	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C6orf164	0.07	0.06	blup	95	0.05	2.0e-03	8.50	-8.7	4.1e-18	0.83	0.05	0.90	FALSE
38	The Cancer Genome Atlas	Colon Adenocarcinoma	C6orf164	0.05	0.02	enet	8	0.02	1.9e-02	8.60	-8.9	4.5e-19	0.89	0.02	0.72	FALSE
39	The Cancer Genome Atlas	Esophageal Carcinoma	C6orf164	0.15	0.07	enet	10	0.04	1.7e-02	-8.47	-7.5	8.7e-14	0.65	0.04	0.66	FALSE
40	The Cancer Genome Atlas	Glioblastoma Multiforme	C6orf162	0.16	0.08	enet	14	0.06	6.7e-03	-8.16	6.5	1.0e-10	-0.62	0.09	0.39	FALSE
41	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C6orf163	0.06	0.04	enet	8	0.04	1.4e-05	-8.62	-6.2	5.4e-10	0.53	0.01	0.97	FALSE
42	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C6orf164	0.06	0.08	blup	94	0.08	8.3e-09	8.60	-8.1	4.6e-16	0.80	0.13	0.87	FALSE
43	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC35A1	0.02	0.01	blup	72	0.00	8.7e-02	6.69	-6.1	9.8e-10	0.60	0.02	0.84	FALSE
44	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C6orf164	0.11	0.12	blup	95	0.14	5.0e-15	8.60	-7.4	1.7e-13	0.78	0.24	0.76	FALSE
45	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C6orf163	0.09	0.04	enet	6	0.09	1.4e-05	-5.40	-6.2	4.3e-10	0.45	0.04	0.71	FALSE
46	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C6orf164	0.11	0.14	enet	8	0.12	1.6e-07	8.51	-8.8	1.0e-18	0.88	0.08	0.92	FALSE
47	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf162	0.05	0.03	blup	72	0.04	2.2e-05	-8.15	6.6	4.2e-11	-0.58	0.35	0.58	FALSE
48	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf164	0.04	0.02	blup	95	0.04	5.4e-05	-8.23	-9.1	8.8e-20	0.84	0.23	0.77	FALSE
49	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF292	0.03	0.02	lasso	3	0.02	7.2e-04	-4.38	7.5	5.9e-14	-0.83	0.04	0.84	FALSE
50	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf164	0.09	0.12	blup	95	0.11	4.1e-13	8.51	-8.5	2.1e-17	0.86	0.08	0.92	FALSE
51	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C6orf164	0.06	0.06	lasso	4	0.07	4.6e-08	8.50	-8.1	3.9e-16	0.84	0.05	0.95	FALSE
52	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf163	0.06	0.02	blup	66	0.02	1.1e-02	-8.22	-8.9	6.9e-19	0.78	0.05	0.74	FALSE
53	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf164	0.12	0.12	blup	95	0.14	7.4e-10	7.83	-8.4	6.2e-17	0.77	0.07	0.93	FALSE
54	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC35A1	0.04	0.03	lasso	5	0.02	1.3e-02	6.81	-7.1	1.6e-12	0.64	0.03	0.73	FALSE
55	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C6orf164	0.07	0.11	enet	8	0.10	8.4e-05	8.55	-8.8	1.3e-18	0.90	0.03	0.93	FALSE
56	The Cancer Genome Atlas	Prostate Adenocarcinoma	C6orf164	0.13	0.10	blup	95	0.11	1.5e-11	8.60	-6.5	7.8e-11	0.59	0.28	0.72	FALSE
57	The Cancer Genome Atlas	Stomach Adenocarcinoma	C6orf164	0.17	0.13	lasso	4	0.10	6.2e-08	8.55	-8.0	9.3e-16	0.80	0.18	0.82	FALSE
58	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C6orf164	0.12	0.08	enet	9	0.09	5.6e-04	-3.32	-6.8	8.5e-12	0.71	0.05	0.85	FALSE
59	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SLC35A1	0.14	0.04	blup	72	0.07	1.4e-03	5.52	-5.8	6.8e-09	0.52	0.01	0.83	FALSE
60	The Cancer Genome Atlas	Thyroid Carcinoma	C6orf164	0.18	0.24	lasso	4	0.25	1.4e-24	8.51	-8.6	6.3e-18	0.88	0.09	0.91	FALSE
61	The Cancer Genome Atlas	Thyroid Carcinoma	SLC35A1	0.08	0.07	enet	17	0.07	5.0e-07	6.69	6.7	2.0e-11	-0.59	0.01	0.99	FALSE
62	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	ORC3L	0.20	0.00	lasso	8	0.00	2.6e-01	-5.07	6.1	9.7e-10	-0.53	0.01	0.25	FALSE