[Hub]/) : Traits : Blood White Count : ← →

chr8:22,181,363-23,781,453

Best TWAS P=5.53e-25 · Best GWAS P=1.02e-29 conditioned to 3.22e-08

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Whole Blood	TNFRSF10B	0.12	0.07	lasso	6	0.07	8.7e-07	10.0	10.3	5.5e-25	0.65	0.03	0.96	TRUE
1	GTEx	Adipose Subcutaneous	TNFRSF10A	0.27	0.09	lasso	7	0.08	2.8e-07	4.9	5.4	6.2e-08	0.09	0.96	0.00	TRUE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	TNFRSF10C	0.13	0.09	blup	53	0.09	6.6e-10	10.0	-10.0	1.5e-23	-0.71	0.25	0.75	FALSE
7	NTR	Blood	TNFRSF10B	0.15	0.11	enet	36	0.12	1.1e-35	10.0	9.7	3.3e-22	0.67	1.00	0.00	FALSE
3	GTEx	Artery Aorta	TNFRSF10B	0.26	0.23	lasso	2	0.22	2.1e-12	6.7	-6.4	1.2e-10	-0.47	1.00	0.00	FALSE
2	GTEx	Adrenal Gland	TNFRSF10C	0.37	0.37	lasso	4	0.36	7.8e-14	-5.5	-6.4	1.7e-10	-0.26	0.99	0.01	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	TNFRSF10C	0.26	0.23	lasso	9	0.21	5.8e-27	-5.5	-6.2	5.6e-10	-0.25	1.00	0.00	FALSE
4	GTEx	Cells Transformed fibroblasts	TNFRSF10A	0.41	0.22	lasso	7	0.33	3.4e-25	4.9	5.6	2.0e-08	0.12	1.00	0.00	FALSE
5	GTEx	Cells Transformed fibroblasts	RP11-1149O23.3	0.19	0.10	lasso	4	0.14	1.7e-10	4.9	5.6	2.2e-08	0.10	1.00	0.00	FALSE