TWAS hub - SLC45A4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.2071	0.0615	4.9e-04	0.002	NA	0.031	NA	0.009	2.0e-01	NA	1.7e-03	NA	5.6e-02
2	GTEx	Breast Mammary Tissue	0.1930	0.0690	6.3e-03	0.014	NA	0.029	NA	0.032	5.8e-02	NA	1.2e-02	NA	9.1e-03
3	GTEx	Breast Mammary Tissue (Male)	0.2872	0.1191	2.8e-02	0.059	NA	-0.009	NA	0.024	1.8e-02	NA	5.7e-01	NA	9.3e-02
4	GTEx	Colon Sigmoid	0.2160	0.0710	2.1e-03	0.159	NA	0.101	NA	0.145	2.9e-06	NA	2.0e-04	NA	8.2e-06
5	GTEx	Esophagus Mucosa	0.3610	0.0540	4.7e-13	0.130	NA	0.257	NA	0.295	5.2e-09	NA	2.6e-17	NA	4.7e-20
6	GTEx	Nerve Tibial	0.1019	0.0400	8.7e-03	0.009	NA	0.002	NA	0.012	6.8e-02	NA	2.0e-01	NA	4.8e-02
7	GTEx	Spleen	0.5880	0.1200	1.4e-03	0.117	NA	0.105	NA	0.304	6.4e-04	NA	1.2e-03	NA	1.5e-08
8	GTEx	Vagina	0.6740	0.1500	3.6e-03	-0.005	NA	0.019	NA	0.015	4.3e-01	NA	1.2e-01	NA	1.5e-01
9	GTEx	Whole Blood	0.2000	0.0460	5.8e-06	0.171	NA	0.148	NA	0.163	1.3e-15	NA	1.6e-13	NA	7.6e-15
10	NTR	Blood	0.0523	0.0142	5.4e-06	0.044	0.026	0.042	0.046	0.045	5.1e-14	5.0e-09	2.0e-13	1.1e-14	2.2e-14
11	ROSMAP	Brain Pre-frontal Cortex	0.1005	0.0268	3.5e-06	0.072	0.051	0.047	0.056	0.047	1.3e-09	3.1e-07	9.7e-07	1.1e-07	1.1e-06
12	TCGA	Head and Neck Squamous Cell Carcinoma	0.0448	0.0219	2.0e-03	0.010	0.041	0.032	NA	0.017	2.1e-02	2.1e-05	1.5e-04	NA	4.6e-03
13	TCGA	Prostate Adenocarcinoma	0.0353	0.0173	6.4e-04	0.045	0.021	0.023	NA	0.035	1.5e-05	2.3e-03	1.7e-03	NA	1.3e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	9	10	11	12	13
Blood White Count	7.1	52.4	174.2	-0.5	5.4	5.2	8.1	-7.3	1.1	9.5	13.2	12.2	5.1	2.1	7.8
Birth weight	5.4	11.8	21.8	1.9	-3.7	-4.2	-4.7	4.7	-1.4	-3.3	-4.4	-3.8	-3.4	-0.2	-4.1
Health satisfaction	3.4	4.4	11.6	1.3	-2.1	-1.9	-0.9	3.4	1.3	-2.1	-2.8	-2.8	-2.1	2.2	-1.9
Mouth/teeth dental problems: Bleeding gums	3.3	4.3	12.7	1.1	-2.3	-1.5	-1.3	3.6	1.1	-2.2	-2.4	-2.8	-2.7	0.9	-2.2
Age at first live birth	3.3	5.8	18.2	2.4	3.3	1.8	3.2	-1.0	1.8	0.4	-1.3	-1.5	3.9	1.9	4.3
Average weekly spirits intake	3.2	4.0	15.8	-1.9	-1.7	-0.8	-2.2	-1.5	-2.5	1.1	1.3	2.0	-1.9	-4.0	-2.1
Medication for pain relief, constipation, heartburn	3.1	5.3	17.1	0.7	3.4	1.7	3.1	-1.7	2.4	1.4	1.6	1.1	4.1	0.8	3.6
Back pain experienced in last month	3.1	4.5	10.5	1.7	-2.7	-0.6	-2.3	3.0	-1.4	-1.8	-2.3	-1.9	-3.2	0.2	-3.0
Medication: Paracetamol	3.0	4.9	19.6	-0.4	-3.4	-2.7	-2.4	1.4	-2.2	-0.8	-1.1	-0.5	-4.4	-0.7	-3.2
Hearing aid user	2.8	3.1	9.3	-0.8	-2.2	-1.4	-2.7	-0.2	-1.3	-0.6	-1.2	-0.9	-3.1	-2.1	-2.8
Age at First Birth	2.7	3.9	14.4	-0.1	3.8	2.0	2.9	-0.8	1.5	0.6	0.3	0.1	3.3	0.8	3.0
Mouth/teeth dental problems: Loose teeth	2.6	3.1	8.3	0.7	-1.7	-1.1	-1.6	1.9	-0.6	-2.0	-2.9	-2.7	-2.3	-0.8	-1.9
Osteoarthritis (self-reported)	2.6	3.3	7.5	-1.6	-1.5	0.3	-2.5	-0.4	-2.7	0.8	1.4	1.9	-2.3	-2.6	-2.4
Age at last live birth	2.5	3.6	9.3	2.0	1.3	-0.1	1.9	1.3	3.0	-1.2	-2.4	-2.6	1.9	2.0	2.2
Knee pain experienced in last month	2.5	3.8	13.3	-1.4	-2.2	-1.8	-2.4	2.7	-0.8	0.9	-0.0	-0.3	-3.6	-0.9	-3.4
Medication: Paracetamol	2.5	3.8	13.4	-0.5	-3.0	-2.1	-1.9	0.3	-2.8	-1.3	-0.9	-0.4	-3.7	-1.2	-2.6
Hair/balding pattern: Pattern 2	2.3	3.0	10.1	-0.0	1.4	2.4	3.2	-1.1	1.8	0.8	1.4	1.0	2.3	1.1	2.5
Birth weight of first child	2.3	4.1	8.9	0.9	-2.6	-1.3	-2.9	3.0	-0.7	-1.3	-2.2	-1.8	-2.8	-0.2	-2.9
Pulse rate, automated reading	2.3	7.5	20.1	0.1	-3.3	-4.5	-3.7	1.4	-1.7	-2.5	-1.5	-0.7	-4.4	-1.2	-4.3
Alzheimer’s Disease (in father)	2.2	2.4	8.9	-0.6	0.1	1.0	-0.3	-2.3	-0.7	1.1	2.8	3.0	-0.2	-2.5	-0.2
Qualifications: CSEs or equivalent	2.2	2.9	12.0	-1.1	-2.8	-2.5	-0.6	1.6	1.0	-0.1	0.9	0.4	-3.5	0.3	-2.2
Mouth/teeth dental problems	2.2	3.3	12.9	0.4	2.9	1.5	1.9	-1.9	0.6	1.4	0.7	1.0	3.6	-0.2	2.9
Hayfever/allergic rhinitis (self-reported)	2.2	2.9	6.4	-2.0	-2.4	-1.7	-1.8	-1.1	-1.7	1.7	0.9	1.3	-1.7	-2.5	-1.7
Number of full sisters	2.2	2.7	6.2	-1.3	-1.6	-2.4	-1.4	0.3	-1.7	0.3	1.4	1.8	-1.6	-2.5	-2.4
Mother’s age at death	2.2	2.7	6.7	1.1	2.6	-0.2	2.3	-1.6	1.0	2.0	1.7	1.3	1.8	1.0	2.4
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.5	6.7	1.2	2.6	0.3	1.8	-0.7	0.2	-1.1	-1.6	-1.6	2.6	1.4	2.3
Leg pain on walking	2.1	2.7	7.1	-0.7	-2.5	-2.6	-0.2	2.4	0.2	-0.6	-0.9	-1.4	-2.7	-0.4	-2.2
Eye problems/disorders: Glaucoma	2.0	2.4	9.5	2.3	-0.2	0.3	-0.3	1.3	0.9	-0.6	-3.1	-3.1	0.2	1.8	-0.0
Age started oral contraceptive pill	2.0	2.6	5.9	1.2	2.3	1.8	1.3	-2.0	-1.2	1.3	1.5	1.5	2.4	-0.5	1.9
Ovarian Cancer	1.9	2.5	5.4	0.9	-2.2	-1.5	-1.3	2.3	-0.2	-0.1	-1.7	-1.6	-2.3	0.5	-2.3
Multivitamins +/- minerals	1.9	2.4	7.7	0.8	2.0	2.5	2.2	-0.5	0.2	0.5	-0.1	-0.3	2.8	1.3	2.2
High blood pressure (siblings)	1.9	2.7	6.0	-1.2	2.5	0.3	2.1	-1.4	0.2	1.5	2.1	2.2	2.3	-1.3	1.8
Illnesses of siblings: Diabetes	1.9	2.3	4.8	-1.4	-1.6	-1.1	-0.6	-1.5	-1.3	2.0	2.0	2.2	-1.2	-1.8	-1.3
Pain experienced in last month	1.9	3.2	12.6	-0.2	2.8	1.0	1.1	-2.8	0.0	0.6	1.2	1.2	3.5	-0.1	2.7
Primary Biliary Cirrhosis	1.8	2.6	6.5	-0.2	1.8	1.9	2.5	-1.3	1.4	1.4	1.9	1.5	2.0	-0.2	2.2
Migraine (self-reported)	1.8	2.2	9.0	1.2	-0.1	0.1	0.5	3.0	2.0	-1.5	-1.5	-2.0	-0.6	2.2	-0.2
Lupus	1.7	2.5	6.6	2.5	1.8	1.2	1.9	0.6	1.9	-1.0	-0.2	-0.2	1.3	2.2	2.6
Hypothyroidism (self reported)	1.7	3.9	11.8	2.1	1.8	0.5	3.1	0.2	1.9	-1.9	-1.4	-2.0	3.4	1.7	2.5
Chronic bronchitis/emphysema (father)	1.7	2.0	7.5	1.1	-1.5	-1.5	-1.2	2.7	0.6	-1.5	-0.4	-0.1	-2.3	0.9	-1.4
Number of incorrect matches in round	1.7	2.8	10.5	-0.1	1.1	2.5	0.8	-3.2	-0.2	1.2	1.6	2.1	1.6	-2.1	1.6
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.2	6.3	-0.4	-1.8	-0.2	-2.5	0.4	-1.2	-1.5	-0.5	0.0	-2.4	-1.5	-2.5
Depression (self-reported)	1.7	2.0	7.2	0.9	0.0	0.7	0.5	2.7	0.9	-2.6	-2.0	-2.1	-0.0	1.4	0.0
Glaucoma (self-reported)	1.7	2.0	7.8	1.7	0.6	0.3	0.5	0.9	0.7	0.0	-2.8	-2.8	1.2	1.9	0.8
Chest pain or discomfort	1.7	2.5	5.9	0.4	-2.4	-0.8	-1.3	2.4	-0.3	-0.6	-2.1	-2.3	-1.9	-0.3	-2.1
Systolic Blood Pressure	1.6	8.1	37.7	0.5	-2.9	-2.8	-6.1	2.7	-0.5	-0.0	-0.1	0.8	-3.2	-0.4	-5.8
Fed-up feelings	1.6	2.9	10.9	-0.4	-2.3	-1.1	-1.5	-0.2	-1.9	0.1	1.5	1.7	-3.3	-1.9	-2.2
Impedance of leg (left)	1.6	7.6	20.6	0.2	-3.9	-0.0	-4.0	1.8	-2.4	-3.4	-2.8	-1.9	-4.5	-0.5	-3.8
Hypothyroidism/myxoedema (self-reported)	1.6	3.2	9.7	2.5	1.6	0.4	2.3	-0.1	2.4	-1.8	-1.3	-1.7	3.1	1.2	1.7
Number of full brothers	1.6	2.1	5.7	-0.2	-1.7	-1.6	-2.0	1.4	-0.5	-0.3	-1.6	-1.3	-2.1	-0.8	-2.4
Medication: Ibuprofen	1.6	1.9	5.6	-0.5	-1.7	0.1	-2.1	0.1	-1.1	-1.3	-0.1	0.4	-2.4	-1.8	-2.3
Illness, injury, bereavement, stress in last 2 years	1.6	1.9	5.9	-0.6	2.4	1.1	1.0	-2.1	-0.4	1.5	0.4	0.5	2.1	0.1	2.0
Long-standing illness, disability or infirmity	1.6	2.5	6.6	-1.4	-2.6	-1.8	-1.5	1.7	-0.5	0.1	-0.7	-0.6	-2.3	-2.0	-2.4
High cholesterol (Self-reported)	1.6	2.8	9.6	3.1	0.8	1.6	0.6	2.0	1.8	-1.0	-1.7	-1.6	-0.0	3.0	0.5
Schizophrenia (2018)	1.5	3.0	9.6	-1.5	-2.0	-0.6	-2.1	-1.2	-3.1	-0.1	0.7	1.5	-1.3	-3.1	-1.8
Supplements: Zinc	1.5	1.6	4.2	1.4	1.4	1.6	1.3	-0.6	1.6	1.1	0.3	0.2	2.1	0.9	2.0
Impedance of leg (right)	1.5	7.1	20.0	0.6	-4.0	0.2	-3.7	2.0	-1.9	-3.6	-2.5	-1.9	-4.5	0.0	-3.5
Mouth/teeth dental problems: Dentures	1.5	2.6	9.0	-1.3	-2.2	-1.2	-2.4	0.8	-1.7	-0.3	0.2	0.1	-3.0	-0.2	-2.7
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	3.9	-1.8	-2.0	-1.8	-1.9	0.1	-0.6	-1.3	0.2	0.5	-1.7	-0.7	-1.9
Mood swings	1.5	2.7	8.9	-1.6	-2.1	-1.4	-2.0	-0.7	-2.1	-0.4	0.4	0.8	-3.0	-2.1	-1.9
Medication: Bendroflumethiazide	1.5	2.4	7.2	1.2	0.8	1.6	0.6	-0.7	1.8	1.4	2.7	2.5	1.7	1.6	1.2
Fractured/broken bones in last 5 years	1.5	1.9	4.5	-0.3	-0.9	-0.8	-1.5	2.1	-0.3	-1.2	-2.1	-2.1	-1.6	0.7	-1.8
Myopia	1.5	2.2	6.1	0.4	2.5	1.1	1.8	-1.8	-0.3	1.5	1.2	1.0	2.1	0.1	2.2
Cholesterol lowering medication	1.5	2.1	6.4	1.5	-2.1	0.2	-0.9	2.3	0.1	-1.5	-1.0	-1.2	-2.5	0.8	-1.8
Alcohol drinker status: Previous	1.5	1.7	4.5	-1.9	-1.2	-1.1	-0.8	2.1	-0.8	-1.2	-0.5	-0.9	-2.0	-0.6	-1.7
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	4.6	0.9	-1.8	-1.4	-1.7	1.5	-1.1	0.5	0.7	0.8	-1.6	0.1	-2.1
Shortness of breath walking on level ground	1.4	1.6	5.1	0.3	-2.1	-1.0	-1.4	1.2	-1.0	-0.1	0.2	0.4	-2.3	-0.9	-2.2
Bipolar Disorder (2011)	1.3	1.2	7.2	-2.7	0.3	0.6	1.2	-1.6	0.3	-0.3	1.5	1.3	-0.1	-0.9	0.1
Coronary Artery Disease (CAD)	1.3	1.5	7.7	1.7	1.1	1.2	0.4	0.8	2.8	-0.4	-0.6	-0.6	0.4	2.0	0.7
Vitamin and mineral supplements	1.3	1.8	6.7	-0.5	-1.8	-2.6	-1.5	1.2	-0.2	-0.4	-0.5	-0.4	-2.3	-0.8	-1.8
Townsend deprivation index at recruitment	1.3	1.8	5.7	-1.8	-2.2	-1.2	-1.2	-0.0	-1.4	0.3	0.2	0.0	-2.4	-1.4	-1.9
Loud music exposure frequency	1.3	1.4	4.8	-0.5	-1.6	-1.3	-1.4	-0.0	-1.4	-0.9	0.2	0.6	-2.2	-1.3	-1.6
Emphysema/chronic bronchitis	1.3	1.4	5.9	0.8	-1.9	-1.5	-0.5	2.4	0.2	-1.2	-0.7	-0.8	-1.3	0.7	-1.1
Number of operations (self-reported)	1.3	2.0	8.2	-0.2	-1.7	-1.9	-0.8	2.9	1.4	-0.6	-1.0	-1.0	-1.9	1.0	-1.0
Intelligence (Savage-Jansen 2018)	1.2	3.6	15.5	2.2	2.7	0.9	1.2	-1.5	1.2	2.1	1.1	0.8	3.9	1.5	2.1
Crohns Disease (2017)	1.2	2.7	9.2	1.1	-0.8	-0.5	-0.7	3.0	0.3	-2.9	-2.2	-2.2	-1.7	0.7	-1.0
HDL Cholesterol	1.2	2.0	6.7	-2.3	-0.3	-1.6	-0.3	-1.4	-1.7	1.2	1.4	1.5	-0.5	-2.6	-0.7
Hearing difficulty/problems: Yes	1.2	1.9	5.7	1.0	-1.4	-0.9	-1.4	0.3	-1.4	-2.0	-1.5	-1.1	-2.4	-0.2	-1.7
Pack years adult smoking proportion	1.2	1.8	4.9	-0.3	-2.2	-1.4	-1.3	2.0	-0.8	0.1	-0.5	-0.4	-2.0	-1.0	-2.1
Serious illness, injury or assault to yourself	1.2	1.4	3.7	-1.0	-1.3	-1.1	-1.1	0.9	-0.2	-1.9	-1.1	-1.0	-1.7	-1.2	-1.5
Alcohol usually taken with meals	1.2	1.9	4.4	1.9	1.8	1.8	1.2	-0.9	0.4	0.1	-1.1	-1.2	2.1	0.7	2.1
Illnesses of siblings	1.2	1.7	3.2	1.6	-1.6	-0.1	-1.8	1.5	0.6	-0.9	-1.7	-1.7	-1.0	1.4	-1.1
Noisy workplace	1.2	1.5	3.8	0.0	-1.0	-0.5	-0.6	1.9	0.6	-1.7	-1.9	-1.7	-1.7	-0.4	-1.4
Length of working week for main job	1.2	1.3	2.9	-1.6	-1.7	0.1	-1.3	-1.0	-1.2	0.9	0.8	1.0	-1.6	-1.1	-1.3
Commuting to job workplace: Car/motor vehicle	1.2	1.4	4.7	1.1	-0.9	-0.9	-0.9	2.2	1.1	-1.0	-1.0	-1.0	-0.6	2.0	-0.9
Mineral and other dietary supplements	1.2	1.6	4.8	0.6	-1.6	-2.2	0.2	1.6	1.1	-1.5	-0.7	-0.8	-2.1	0.5	-1.2
Ever taken oral contraceptive pill	1.2	1.3	3.6	0.3	-1.8	-1.7	-1.3	1.4	1.0	-0.6	-0.0	0.1	-1.6	0.1	-1.9
Financial situation satisfaction	1.2	1.5	5.2	-0.2	-1.9	-1.5	-1.2	-0.0	-1.2	-1.0	-0.3	-0.2	-2.3	-0.4	-1.9
Unable to work because of sickness or disability	1.2	1.6	5.4	0.9	-1.1	-0.8	-1.7	1.3	0.2	-2.3	-1.0	-0.8	-1.4	1.4	-1.4
Bipolar Disorder (2018)	1.1	1.7	7.2	-1.6	1.0	-0.4	2.7	-1.1	0.1	0.3	1.7	1.4	1.6	-0.6	1.7
LDL Cholesterol	1.1	1.8	4.9	1.4	1.1	1.4	0.5	-1.8	0.4	2.2	1.6	2.1	1.3	0.5	1.2
Financial difficulties in last 2 years	1.1	1.5	5.1	0.6	-2.3	-1.1	-1.3	0.8	-0.3	-1.4	-1.0	-0.9	-1.9	-0.4	-1.9
Pain all over the body in last month	1.1	1.2	4.5	-0.9	-1.6	-2.1	-0.7	1.0	-0.6	-1.5	0.1	0.1	-1.4	-0.3	-1.2
Lung cancer (father)	1.1	1.3	4.8	1.1	-0.8	-0.9	0.5	2.2	1.6	-0.6	-0.5	-1.0	-1.4	1.2	-1.0
Exposure to tobacco smoke at home	1.1	1.3	3.5	-0.5	-1.6	-1.1	-1.0	1.9	0.6	-0.8	-0.3	-0.5	-1.7	0.4	-1.9
Headache pain in last month	1.1	1.9	7.5	1.3	-2.2	-1.2	-1.0	1.1	-0.9	-0.9	-0.9	-0.8	-2.7	0.2	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.3	8.6	0.5	-0.5	-1.2	-0.1	1.5	1.0	-2.6	-2.9	-2.8	0.3	1.1	-1.0
Medication: Atorvastatin	1.1	1.4	3.1	0.2	-1.2	-1.4	-1.6	1.4	-0.5	0.4	-1.4	-1.3	-1.8	0.8	-1.6
Pack years of smoking	1.1	1.7	4.3	-0.7	-2.1	-1.2	-1.3	1.6	-0.9	0.6	-0.0	-0.1	-2.0	-1.3	-2.0
Triglycerides	1.0	1.7	5.5	2.2	0.8	1.2	1.2	0.5	1.5	0.4	-0.4	-0.7	1.7	2.3	1.5
Allergy or Eczema	1.0	2.5	10.4	-2.2	-1.3	-1.1	0.1	-1.3	-2.0	3.2	1.9	1.4	-0.7	-1.8	-0.4
Hayfever, allergic rhinitis or eczema	1.0	2.1	5.3	-1.6	-1.7	-1.6	-0.5	-1.4	-0.8	2.3	1.8	1.6	-1.3	-1.9	-0.9
Sitting height	1.0	7.2	20.6	3.4	2.9	2.1	2.1	0.5	2.9	-0.4	-3.0	-3.0	4.5	3.0	3.0
Qualifications: None of the above	1.0	2.2	7.7	-1.1	-1.1	-0.0	-1.5	1.8	0.2	-2.2	-1.5	-1.4	-2.8	-0.4	-2.0
Ever highly irritable/argumentative for 2 days	1.0	1.2	4.6	1.7	-0.2	0.7	0.3	1.4	1.0	-2.2	-0.6	-0.5	-0.2	1.9	-0.2
Medication: Amlodipine	1.0	1.4	5.3	-0.5	0.1	-1.2	-2.3	-1.0	-0.9	1.8	1.0	1.4	-1.2	-0.9	-1.3
Neck or shoulder pain in last month	1.0	1.5	7.2	0.1	-1.7	-0.6	-0.9	1.9	-0.2	-0.2	-0.2	-0.2	-2.7	-0.1	-2.0
Medication: Allopurinol	1.0	1.3	3.2	-1.0	1.8	1.3	0.4	-1.2	1.0	0.6	1.5	1.6	1.2	-0.8	1.1
Mean time to correctly identify matches	1.0	1.8	7.1	-0.2	2.7	1.9	1.4	-1.1	0.8	0.2	1.2	1.2	1.6	1.2	1.7
Illnesses of father: Heart disease	1.0	1.4	4.3	-1.4	0.1	-0.2	-1.6	-0.7	-0.7	1.5	1.8	2.1	-0.6	-1.0	-1.4
Smoking status: Current	1.0	1.5	5.5	-1.7	-0.9	-0.4	-0.7	0.2	-1.1	0.9	1.4	1.5	-2.4	-0.7	-1.8
Bipolar Disorder or Schizophrenia	0.9	2.2	7.6	-2.2	-0.9	-0.8	0.1	-1.6	-2.3	0.1	1.6	2.1	0.0	-2.8	-0.4
Depressed Affect (Nagel 2018)	0.9	2.0	6.9	-0.1	-1.6	-0.4	-1.6	-0.7	-2.1	-1.1	0.8	0.9	-2.6	-1.5	-1.9
Depression (Nagel 2018)	0.9	1.3	3.0	-0.6	-1.5	-0.2	-1.0	-0.8	-1.0	0.1	1.6	1.6	-1.7	-1.4	-1.3
Reaction Time	0.9	1.8	4.0	-1.0	2.0	1.8	1.7	-1.0	0.9	0.6	1.8	1.6	0.9	1.3	1.2
Schizophrenia (2014)	0.9	2.1	8.1	-1.4	-1.6	-0.7	-1.5	-0.9	-2.5	-0.8	0.1	0.8	-1.0	-2.9	-1.4
Systolic blood pressure, automated reading	0.9	2.7	11.2	0.2	-0.9	-1.5	-3.4	1.9	-2.3	0.1	0.0	0.4	-1.3	-0.6	-3.0
Leg fat-free mass (left)	0.9	4.9	16.8	0.3	3.0	1.1	3.7	-0.4	2.8	1.7	0.5	0.1	4.1	0.9	3.3
Current tobacco smoking	0.9	1.4	4.8	-1.9	-0.8	-0.4	-0.9	0.3	-1.2	0.6	1.1	1.2	-2.2	-0.8	-1.9
High blood pressure (mother)	0.9	1.3	3.5	1.1	1.4	0.5	1.3	-0.2	1.3	1.9	1.2	1.5	1.1	0.4	1.1
Leg predicted mass (left)	0.9	5.0	16.6	0.3	3.1	1.2	3.7	-0.4	2.8	1.7	0.5	0.1	4.1	0.8	3.4
Allergy	0.9	2.2	5.3	2.2	2.1	1.9	0.0	0.6	-0.0	-2.3	-1.6	-1.0	1.6	1.7	0.8
Number of live births	0.9	1.3	3.9	-0.1	-1.4	-0.7	-1.9	1.0	-0.4	-0.7	-0.9	-0.6	-1.4	-1.2	-2.0
Pulse rate	0.9	1.5	4.0	0.7	-1.4	-1.5	-1.3	0.5	-1.3	-1.9	-1.1	-0.6	-2.0	0.5	-1.5
Chronic bronchitis/emphysema (mother)	0.9	1.1	3.2	0.1	-1.1	-1.5	-1.1	0.2	-1.1	-0.4	-0.7	-0.3	-1.8	-1.7	-1.1
Number of children fathered	0.9	1.0	2.3	-1.5	-1.3	-1.5	-1.0	0.5	-1.1	-0.0	-0.1	-0.1	-1.5	-1.0	-1.0
Leg fat-free mass (right)	0.9	5.0	18.4	0.3	3.2	0.9	3.6	-0.4	2.7	1.9	0.4	0.1	4.3	0.8	3.3
Leg predicted mass (right)	0.9	5.0	18.3	0.3	3.2	0.9	3.6	-0.4	2.7	1.9	0.4	0.2	4.3	0.8	3.3
Tinnitus: Yes, now most or all of the time	0.9	1.1	4.1	0.4	-0.5	1.5	-1.5	-0.6	-1.4	-0.3	-1.2	-0.5	-0.8	-2.0	-0.8
Crohns Disease (2012)	0.8	1.2	3.4	0.6	0.1	-0.3	-0.5	1.7	1.0	-1.7	-1.8	-1.6	-1.1	0.8	-0.7
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	3.3	-0.2	0.2	1.0	0.9	0.9	1.8	0.4	1.2	0.5	-0.5	1.6	0.5
Medication: Levothyroxine sodium	0.8	1.3	3.3	1.8	-0.1	-0.9	1.0	1.2	1.4	-1.5	-0.5	-1.0	1.5	1.8	0.3
Had other major operations	0.8	0.9	2.9	-0.8	-1.7	-1.0	0.1	1.7	-0.2	-1.2	-0.3	-0.5	-1.4	-0.5	-0.7
Breastfed as a baby	0.8	1.1	3.5	0.1	1.6	-0.4	0.7	-1.1	0.3	1.1	1.1	1.2	1.9	0.3	1.2
Arm fat-free mass (right)	0.8	4.3	14.8	1.0	2.7	1.7	3.2	0.4	2.8	0.4	-1.0	-1.3	3.8	1.0	2.9
Wheeze or whistling in the chest in last year	0.8	1.5	5.5	-0.2	-0.9	-2.4	-0.3	1.8	0.6	0.1	0.8	0.6	-2.3	-0.5	-1.5
Angina (self-reported)	0.8	1.1	2.2	-0.0	-1.4	-0.5	-1.3	1.5	0.5	-0.3	-1.4	-1.4	-1.3	-0.6	-1.2
Arm predicted mass (right)	0.8	4.2	15.4	1.0	2.7	1.6	3.2	0.2	2.6	0.7	-0.8	-1.0	3.9	0.9	2.9
Arm fat percentage (left)	0.8	3.0	9.1	-2.8	1.2	0.5	2.1	-0.7	1.0	1.9	3.0	2.7	0.6	-1.1	1.3
Medication: Aspirin	0.8	1.0	2.4	-1.2	-1.4	-0.6	-0.9	-0.6	-1.0	0.9	1.0	1.0	-0.8	-1.2	-1.5
Whole body water mass	0.8	4.3	15.2	1.3	2.7	1.0	3.4	0.2	2.8	0.9	-0.6	-0.9	3.9	1.2	2.9
Pain type(s) experienced in last month: Hip pain	0.8	1.0	2.8	1.6	-0.9	0.5	0.1	1.5	1.7	1.3	-0.0	-0.5	-0.7	1.3	-0.3
Ever smoked	0.8	1.4	3.9	-1.2	1.2	1.3	0.0	-0.9	-1.0	1.8	2.0	1.9	-0.3	-0.5	-0.0
Neuroticism (Nagel 2018)	0.7	1.7	5.7	-0.1	-1.0	0.7	-0.4	-1.9	-1.6	0.3	2.4	2.3	-0.9	-1.4	-0.3
Verbal and Numeric Reasoning (VNR)	0.7	1.6	7.9	1.5	1.8	0.1	0.6	-0.7	0.7	1.1	-0.1	-0.0	2.8	1.7	1.3
Blood Eosinophil Count	0.7	5.4	13.9	-2.2	-3.7	-2.5	-1.3	1.6	-1.5	1.2	2.5	2.1	-3.7	-1.6	-3.2
Height	0.7	13.2	41.3	4.3	4.6	3.0	3.1	-0.8	2.4	-0.6	-3.8	-3.6	6.4	4.2	4.5
Frequency of depressed mood in last 2 weeks	0.7	1.0	3.7	-1.2	-1.1	0.5	-0.3	-1.1	-0.5	0.2	0.8	0.8	-1.6	-1.9	-0.5
Angina	0.7	1.0	2.1	-0.0	-1.4	-0.2	-1.2	1.3	0.6	-0.3	-1.4	-1.4	-1.1	-0.9	-1.1
Medication for hormone replacement therapy	0.7	0.8	2.4	0.8	-0.9	0.3	-1.5	1.5	0.2	0.5	-0.3	-0.1	-1.3	0.5	-1.5
High blood pressure	0.7	2.0	9.8	0.9	1.7	1.1	0.2	-1.1	-0.1	2.0	1.1	1.6	3.1	0.5	1.3
Arm fat percentage (right)	0.7	2.6	8.4	-2.6	0.9	0.2	2.1	-0.5	1.0	1.7	2.9	2.6	0.1	-1.2	1.1
Trunk fat-free mass	0.7	3.8	12.5	1.9	2.2	0.7	2.9	0.5	2.7	0.5	-1.2	-1.5	3.5	1.4	2.5
Hair/balding pattern: Pattern 3	0.7	1.0	3.0	0.1	-1.6	-0.8	-1.5	-0.2	-1.7	-0.2	-0.6	-0.3	-0.9	-0.9	-1.4
Trunk predicted mass	0.7	3.9	12.6	1.9	2.2	0.7	2.8	0.5	2.7	0.5	-1.4	-1.6	3.6	1.4	2.5
Standing height	0.7	7.4	17.8	4.0	2.1	1.6	1.5	1.2	2.1	-1.1	-4.2	-4.1	3.7	3.1	2.3
Tense / ‘highly strung’	0.7	1.1	3.3	-1.1	0.1	0.8	0.9	-1.6	-1.0	1.0	1.1	1.0	1.8	-0.8	1.3
Medication: Ventolin 100micrograms inhaler	0.7	0.9	3.3	-1.0	-1.5	-1.8	0.1	0.7	1.0	-0.2	1.1	0.5	-1.1	0.6	-0.9
Comparative body size at age 10	0.7	1.8	3.7	-1.9	0.6	1.2	0.8	-0.8	0.2	1.7	1.9	1.5	1.4	-1.8	1.5
Qualifications: College or University degree	0.7	2.1	9.7	2.1	0.9	0.0	0.9	-2.0	-0.5	1.2	-0.4	-0.0	3.1	-0.7	2.2
Medication: Seretide 50 evohaler	0.7	0.9	2.4	-0.5	-0.8	-1.1	1.0	1.6	1.4	0.9	0.7	-0.2	-0.2	1.4	-0.0
Supplements: Vitamin C	0.7	0.9	5.7	0.0	0.9	0.9	-0.0	-2.4	-1.0	0.3	0.9	1.1	0.7	-0.3	0.3
Hypertension (Self-reported)	0.7	1.9	9.0	0.4	1.7	1.2	0.4	-1.0	-0.1	2.0	1.2	1.7	3.0	0.2	1.2
Whole body fat-free mass	0.7	4.2	14.8	1.2	2.7	1.0	3.3	0.2	2.8	0.8	-0.6	-0.9	3.9	1.2	2.9
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.6	0.3	0.4	-0.6	1.6	-0.9	-0.2	1.6	1.1	0.7	0.8	0.8	1.0
Wears glasses or contact lenses	0.7	0.9	3.1	0.1	1.8	0.8	1.0	-0.2	1.6	0.5	-0.2	-0.6	0.9	0.4	1.5
Basal metabolic rate	0.7	4.1	13.0	0.8	2.6	1.1	3.4	0.3	3.0	0.9	-0.3	-0.6	3.6	1.0	2.9
Arm fat-free mass (left)	0.7	3.6	11.1	1.0	2.4	1.4	3.3	0.5	2.7	0.2	-0.6	-0.9	3.3	0.8	2.6
Irritability	0.7	1.2	4.1	-0.6	-0.4	1.1	0.2	-1.1	-0.7	0.9	2.0	2.0	1.0	-1.1	0.9
Ever had prostate specific antigen (PSA) test	0.7	0.8	3.5	-0.6	0.4	1.0	-1.0	-1.1	-1.9	0.6	-0.0	-0.0	-0.1	-1.6	-0.6
Basal cell carcinoma (self-reported)	0.7	0.8	4.6	2.1	-1.6	-0.4	-1.1	1.1	0.2	-0.2	-0.3	-0.3	-0.6	0.5	-0.8
Impedance of whole body	0.7	3.6	9.7	0.0	-2.6	0.2	-3.1	0.8	-2.3	-2.2	-1.8	-1.2	-3.0	0.2	-2.4
Arm predicted mass (left)	0.7	3.6	11.0	1.1	2.4	1.4	3.3	0.6	2.6	0.2	-0.7	-1.0	3.3	0.8	2.7
Worry (Nagel 2018)	0.6	1.4	4.8	0.2	0.3	1.7	0.9	-2.2	-0.3	1.3	1.7	1.5	0.9	-0.5	1.2
Type 2 Diabetes (T2D) (2012)	0.6	0.6	2.5	-0.0	-0.6	-1.6	-1.3	1.4	0.3	0.1	-0.6	-0.4	-0.9	0.1	-0.8
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.6	-0.1	0.6	-0.9	0.0	-1.6	-0.2	0.8	1.1	1.3	0.3	-1.0	0.1
Severe depression (siblings)	0.6	0.7	1.5	-0.8	0.2	-0.6	-0.9	-0.8	-1.2	1.1	0.7	0.9	0.6	-1.1	-0.6
Average weekly fortified wine intake	0.6	0.6	2.9	0.2	-0.3	-0.4	-0.4	1.0	0.9	-0.6	-1.5	-1.7	-0.8	0.4	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.2	-1.3	-1.5	-0.9	-0.4	0.0	0.2	0.6	0.7	0.9	-1.3	-1.3	-1.0
Relative age voice broke	0.6	0.9	2.6	-0.7	0.7	-1.4	-0.1	1.1	0.4	-1.3	-1.6	-1.5	0.4	-0.1	-0.2
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.6	-0.2	0.3	-1.2	0.7	-0.6	-1.2	0.8	0.6	0.8	1.0	-1.6	0.7
Body mass index (BMI)	0.6	2.7	6.6	-2.1	1.6	0.8	2.6	-0.6	1.5	1.7	2.4	2.1	1.3	-1.0	1.6
Had menopause	0.6	0.7	2.9	1.1	1.7	1.3	-0.2	0.1	-0.1	-0.0	0.1	0.1	0.6	1.6	1.0
Medication: Simvastatin	0.6	0.9	3.7	1.9	-0.5	0.6	-0.6	1.9	0.6	-0.9	-0.7	-0.6	-0.9	0.5	-1.1
Weight	0.6	3.0	9.4	-0.3	2.5	1.5	3.1	-0.1	2.3	1.2	0.5	0.3	2.8	0.2	2.5
Prospective memory result	0.6	0.7	2.4	-0.8	0.7	0.7	1.0	0.8	-0.1	-1.0	-1.5	-1.2	0.4	-0.4	0.8
Arm fat mass (right)	0.6	2.5	8.2	-1.6	1.7	0.9	2.9	-0.0	2.1	1.5	1.9	1.6	1.3	-0.2	1.9
Pulse wave reflection index	0.6	0.7	2.2	1.2	1.1	1.4	0.4	0.2	0.2	1.0	-0.1	0.2	1.5	-0.4	1.2
Gout (self-reported)	0.6	0.8	3.6	-0.8	1.9	0.6	0.4	-1.0	0.5	-0.1	0.8	0.9	1.1	-0.3	1.2
Medication: Aspirin	0.6	0.8	2.8	-0.3	-1.7	-0.7	-1.1	-0.0	-1.1	0.8	0.3	0.3	-0.8	-0.9	-1.6
Average weekly red wine intake	0.6	0.8	2.8	1.7	1.0	0.6	0.6	0.6	0.2	0.0	-1.0	-1.5	0.9	0.7	1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	4.0	2.0	-0.3	0.4	-0.5	1.0	0.8	-0.9	-0.4	-0.2	-0.3	1.3	0.4
Commuting to job workplace: Walk	0.6	0.7	2.2	0.1	1.4	1.5	1.0	-1.1	-0.9	-0.5	0.1	0.1	0.4	-0.9	0.8
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	2.9	-0.5	-1.1	-1.3	-0.6	-0.6	-1.7	-0.2	0.6	0.7	-1.2	-1.6	-0.8
Osteoporosis (self-reported)	0.6	0.7	2.5	-0.9	0.2	-1.0	-0.7	1.0	0.6	-1.0	-0.1	-0.6	-1.3	-0.2	-1.6
Illnesses of father: None of the above (group 1)	0.6	0.8	4.0	0.3	-0.2	-0.9	-0.2	-0.8	-2.0	-0.2	-1.3	-1.5	0.7	-0.1	0.5
Arm fat mass (left)	0.6	2.6	8.7	-1.7	1.9	1.0	3.0	-0.2	2.1	1.4	1.8	1.5	1.5	-0.4	1.9
Supplements: Fish oil (including cod liver oil)	0.6	0.7	2.4	-0.4	0.6	1.6	-0.9	-1.3	-1.5	-0.4	-0.7	-0.5	0.9	-0.7	0.0
Average weekly beer plus cider intake	0.6	0.9	3.1	-1.7	-0.8	-1.3	-1.2	-1.2	-1.0	0.6	0.4	0.7	-0.6	-0.2	-1.0
Schizophrenia vs Biploar Disorder	0.5	0.7	2.1	0.5	-0.6	1.5	-1.1	0.4	-0.2	-0.8	-1.4	-1.0	-0.7	0.2	-0.9
Alzheimer’s Disease (including proxy)	0.5	0.7	3.3	0.5	0.7	1.0	-0.1	-0.4	-0.3	0.2	1.8	1.8	-0.4	-0.9	-0.3
Ulcerative Colitis (UC)	0.5	1.0	4.0	0.5	1.0	1.4	-0.2	-0.8	-0.8	0.5	1.8	2.0	-0.1	-1.0	0.2
Prostate Cancer	0.5	0.7	1.8	1.1	-0.5	0.8	-0.0	1.3	1.3	-0.9	-0.6	-0.7	-0.8	1.0	-0.4
Fasting Glucose	0.5	0.6	2.0	-1.2	-1.4	-0.5	-0.8	0.8	-0.5	0.1	-0.1	-0.3	-1.1	0.1	-0.8
HbA1C	0.5	0.6	1.4	-0.3	-1.2	-0.8	-0.8	-0.1	-0.4	1.2	1.1	1.1	-0.1	-0.7	-0.5
Smoking Status	0.5	1.1	3.4	-0.2	-0.2	1.8	-0.8	-0.1	-1.4	0.9	1.0	1.2	-1.8	-0.2	-1.3
Lung FEV1/FVC ratio	0.5	2.5	9.2	-0.8	0.3	-2.5	-2.4	-2.3	-3.0	0.9	0.1	0.7	0.9	-1.5	-1.4
Ever used hormone-replacement therapy (HRT)	0.5	0.7	3.6	0.5	0.8	1.9	-0.3	-0.6	-0.6	1.2	0.9	0.9	-0.1	-0.6	0.1
Ever had hysterectomy (womb removed)	0.5	0.6	3.2	-1.8	0.1	0.3	-1.1	-0.4	-1.1	0.9	-0.2	0.3	0.3	-0.9	-0.5
Medication: Co-codamol	0.5	0.5	1.9	-1.1	-1.4	0.0	-0.4	0.5	0.2	0.2	1.2	1.0	-0.7	-0.3	-0.6
Maternal smoking around birth	0.5	0.7	2.3	0.9	-1.2	-0.5	-0.8	1.2	0.4	-0.6	0.2	0.1	-1.5	0.7	-1.1
Taking other prescription medications	0.5	0.8	2.3	0.0	-0.6	-1.1	-0.3	1.2	-0.4	-0.3	-1.5	-1.5	-0.7	-0.7	-1.1
Bilateral oophorectomy (both ovaries removed)	0.5	0.5	1.6	-0.3	-0.2	1.2	-0.4	-1.2	-1.0	1.3	0.1	0.2	-0.6	-0.8	-0.1
Supplements: Glucosamine	0.5	0.7	2.1	-0.3	0.8	1.3	-0.7	-0.6	-1.5	1.0	0.5	0.9	0.7	-0.9	0.1
Waist circumference	0.5	1.7	6.6	-0.5	1.3	1.0	2.6	0.2	2.1	1.5	1.2	0.8	1.0	0.4	1.6
Hearing difficulty/problems with background noise	0.5	0.8	3.0	0.9	-0.0	0.1	0.0	0.2	-1.1	-1.2	-1.7	-1.7	-0.6	0.4	0.2
Medication: Ramipril	0.5	0.6	1.8	-0.9	0.9	1.0	-1.1	-0.6	-0.6	1.3	0.6	0.8	0.4	-0.2	-0.3
Fluid intelligence score	0.5	1.1	3.8	1.1	0.9	-0.4	-0.1	-1.9	0.1	1.0	0.6	0.7	1.9	1.3	0.9
Neuroticism score	0.5	1.0	3.2	-0.3	-0.8	1.1	-0.3	-1.5	-0.9	0.4	1.8	1.8	-0.1	-1.1	0.2
Falls in the last year	0.5	0.6	3.0	-0.5	-0.7	0.7	0.3	1.7	0.4	-0.5	-0.4	-0.9	-1.4	0.8	-0.0
Asthma	0.5	0.9	6.3	-0.4	-0.9	-0.6	1.3	1.0	2.5	0.3	0.7	0.1	-0.5	0.5	-0.0
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	2.8	0.6	0.9	-0.1	1.5	-0.8	-0.1	1.0	0.5	0.2	1.7	0.1	1.1
Pulse wave peak to peak time	0.5	0.6	2.0	-0.5	0.6	-0.7	1.4	-0.8	-0.1	-0.4	-0.7	-0.8	1.2	0.6	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.8	-0.6	0.8	-0.3	0.6	0.5	0.2	0.7	1.7	1.4	-0.5	-0.1	0.2
Suffer from ‘nerves’	0.5	0.7	2.7	-0.5	0.2	1.5	1.3	-1.6	1.0	-0.3	-0.1	-0.2	0.7	-0.4	1.0
Overall health rating	0.5	1.0	4.5	0.3	-0.4	-0.3	-0.3	1.4	0.7	-1.6	-1.2	-1.1	-2.1	0.3	-1.0
Friendships satisfaction	0.5	0.6	2.4	-0.9	0.9	-0.1	0.2	-1.5	-0.1	0.3	0.7	0.6	1.3	-0.6	0.4
Qualifications: nursing, teaching	0.5	0.7	1.9	0.1	1.2	-1.4	0.4	-1.0	-0.1	0.5	0.5	0.7	1.2	-1.2	0.8
Medication for cholesterol	0.5	0.8	2.2	-1.3	1.0	0.1	1.2	-1.4	-0.3	-0.2	-0.6	-0.7	0.5	-1.5	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	3.2	-0.3	-0.9	-1.6	-0.9	0.2	-1.8	-1.0	-0.8	-0.6	-0.7	-1.0	-1.2
Medication: Blood pressure	0.5	0.9	3.2	1.1	0.3	0.6	-0.8	-0.5	-0.8	0.9	1.4	1.8	1.5	0.6	0.0
Illnesses of father: High blood pressure	0.5	0.6	3.1	-1.1	0.1	1.5	0.7	0.2	1.8	0.4	0.9	0.6	0.3	-0.1	0.2
Alcohol drinker status: Never	0.5	0.6	2.5	0.9	1.3	0.4	1.6	0.4	-0.2	0.8	0.2	0.1	0.9	0.2	1.0
Risk taking	0.5	0.8	2.3	0.7	-0.9	0.2	-1.3	1.0	0.2	-1.2	0.2	0.3	-1.4	-0.1	-1.5
Vascular/heart problems diagnosed by doctor	0.5	1.3	8.1	-0.8	-1.4	-0.8	-0.1	0.7	0.0	-1.5	-0.7	-1.2	-2.8	-0.0	-1.0
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.0	0.4	0.1	-0.9	-0.8	0.9	0.3	0.4	-1.4	-1.2	-0.4	-0.6	-1.0
Breast Cancer	0.4	1.1	3.9	-0.5	-1.2	-1.2	-1.4	2.0	0.6	0.5	-1.3	-1.1	0.1	0.5	-0.9
Neuroticism (2016)	0.4	0.5	2.1	-0.0	-0.3	-0.1	-0.3	-1.4	-1.0	0.4	1.1	1.3	0.6	-0.3	0.0
Rheumatoid Arthritis	0.4	0.5	1.9	-0.7	-0.7	-0.3	-0.2	-0.7	-1.3	-0.0	0.3	0.6	-0.7	-1.4	-0.7
Heel T-Score	0.4	3.1	8.2	0.5	0.4	1.6	1.2	2.6	1.3	-1.4	-2.3	-2.9	2.4	2.3	1.1
BMI	0.4	2.3	8.1	-1.3	0.5	0.5	2.3	-0.1	0.9	2.2	2.9	2.2	1.2	-0.5	1.4
Waist Hip Ratio (WHR)	0.4	1.8	9.2	2.6	-0.4	0.9	0.8	1.0	1.6	0.1	0.0	-0.1	-1.3	3.0	0.2
Number of treatments/medications taken	0.4	0.7	2.2	-0.1	-1.2	-0.8	-1.2	0.6	-0.8	0.2	0.3	0.4	-1.1	-0.6	-1.5
Sensitivity / hurt feelings	0.4	0.7	3.3	0.5	-0.3	0.9	0.1	-0.6	-0.3	0.2	1.8	1.4	-0.5	1.2	0.4
Relative age of first facial hair	0.4	0.8	3.5	-0.4	1.3	-0.6	1.0	-0.6	0.4	0.9	0.3	0.2	1.9	1.0	0.8
Diabetes (mother)	0.4	0.5	2.0	1.1	-0.3	-0.1	0.4	1.1	0.2	-0.2	-1.2	-1.4	-0.6	0.5	-0.3
Trunk fat percentage	0.4	1.6	5.9	-2.4	1.0	1.0	1.7	-0.3	0.4	1.0	1.7	1.7	0.4	-1.1	1.0
Hand grip strength (right)	0.4	1.1	4.6	0.4	-0.7	0.5	-1.5	0.1	0.3	-1.4	-2.1	-1.6	-0.5	-0.8	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	2.5	-1.0	-1.6	-1.5	-0.6	1.5	0.3	-0.5	-0.5	-0.7	0.5	0.1	-0.9
Trunk fat mass	0.4	1.8	5.5	-1.9	1.6	1.1	2.3	-0.2	1.1	1.2	1.2	1.1	1.3	-0.7	1.6
Nervous feelings	0.4	0.8	3.8	-0.5	-0.4	1.7	0.1	-1.9	0.4	0.8	1.0	0.9	0.3	-0.6	0.7
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.4	-1.1	0.7	-0.1	0.6	1.2	0.7	0.2	0.3	0.2	0.8	0.7	1.0
Heart attack	0.4	0.6	2.0	0.6	0.4	-0.8	-0.3	1.1	0.4	0.4	-1.4	-1.3	-0.0	-0.5	-0.6
Impedance of arm (right)	0.4	1.8	6.7	-0.1	-2.1	-0.6	-2.2	0.5	-1.6	-0.9	-0.7	-0.4	-2.6	0.5	-1.7
Hip circumference	0.4	1.7	6.2	-0.4	1.4	0.7	2.2	0.1	2.5	1.4	0.7	0.4	1.8	-0.0	1.6
Time employed in main current job	0.4	0.4	1.6	-0.4	0.2	0.8	1.3	0.6	1.0	0.3	0.4	-0.2	-0.5	0.4	1.1
Qualifications: A levels/AS levels or equivalent	0.4	0.8	3.0	-0.1	-0.5	-0.0	0.3	-1.7	-0.8	0.0	0.9	0.9	1.7	-1.6	0.2
Medication: Lansoprazole	0.4	0.4	1.5	0.5	-0.2	-1.2	-0.5	1.2	0.1	-0.3	-0.5	-0.4	-0.7	0.9	-0.5
Illnesses of mother	0.4	0.5	2.0	-1.4	-0.8	0.2	-0.1	0.5	0.3	-0.8	-0.8	-1.0	0.2	0.7	-0.2
Pulse wave Arterial Stiffness index	0.4	0.4	1.2	0.8	-0.5	1.0	-1.1	0.8	0.4	0.3	0.5	0.6	-0.7	-0.4	-0.6
Body fat percentage	0.4	1.7	6.9	-2.6	0.7	0.8	1.6	-0.2	0.4	0.9	2.1	2.0	0.1	-1.3	0.8
Leg fat percentage (right)	0.4	1.3	5.1	-2.2	0.0	0.8	1.2	0.0	0.3	0.4	1.7	1.6	-0.7	-1.8	0.3
Worry too long after embarrassment	0.4	0.7	1.5	0.1	-0.9	-0.9	-1.0	-0.4	-0.9	1.1	0.7	0.7	-1.0	-1.2	-0.8
Medication: Blood pressure	0.4	0.6	3.3	0.4	0.8	-0.3	-0.7	-0.6	-0.2	1.8	0.5	0.9	1.1	-0.7	0.1
Heart disease (mother)	0.4	0.5	2.3	0.2	0.1	-0.6	-0.9	0.7	-1.1	-0.1	0.0	0.1	-0.5	-1.5	-0.4
Whole body fat mass	0.4	1.8	5.6	-1.8	1.5	1.1	2.4	-0.1	1.4	1.0	1.4	1.2	1.3	-0.5	1.7
Smoking status: Previous	0.4	0.6	5.1	-0.5	1.3	2.3	-0.4	-0.1	-0.0	0.1	0.0	0.0	0.4	-0.1	0.4
Ever had bowel cancer screening	0.4	0.5	1.9	0.3	-0.3	-0.3	-1.3	1.4	-0.8	0.9	-0.2	-0.2	-0.4	-0.5	-0.8
Breast cancer (self-reported)	0.4	0.5	2.0	-0.0	0.1	-0.4	-0.6	-0.2	0.8	-1.3	-0.5	-0.4	-1.4	0.5	-0.8
Asthma (self-reported)	0.4	0.9	6.5	-0.5	-0.6	-0.5	1.6	0.8	2.5	0.1	0.8	0.1	-0.2	0.5	0.3
Average weekly champagne plus white wine intake	0.4	0.5	2.1	0.1	-1.4	-1.0	-0.9	-0.5	0.0	0.4	0.0	0.1	-0.9	-0.7	-1.1
Guilty feelings	0.4	0.7	2.4	-0.4	-0.5	-0.5	0.1	-0.9	-1.0	0.6	1.6	1.5	0.2	-0.6	0.6
Commuting to job workplace: Public transport	0.4	0.4	1.3	0.8	0.7	0.9	1.1	-0.6	0.6	0.5	0.4	0.1	0.2	-0.5	1.0
Leg fat percentage (left)	0.4	1.5	6.4	-2.5	0.1	0.8	1.1	-0.1	-0.1	0.6	1.7	1.7	-0.6	-2.1	0.2
Ever depressed for a whole week	0.4	0.5	1.9	-0.3	-0.1	-1.0	0.9	1.4	0.9	0.5	0.1	-0.3	-0.2	0.9	0.8
Supplements: Calcium	0.4	0.5	2.5	-1.6	0.1	1.2	-0.4	0.1	-0.1	-0.4	-0.3	-0.4	0.6	-1.1	-0.0
Leg fat mass (left)	0.4	1.5	4.2	-2.0	1.0	1.0	1.9	0.0	1.2	1.0	1.5	1.3	0.7	-1.2	1.1
Alzheimer’s Disease (in mother)	0.3	0.4	1.1	0.0	0.0	0.6	-0.9	1.0	-1.1	-0.5	0.2	0.3	-0.9	-0.1	-0.8
Irritable Bowel Disease (IBD)	0.3	0.6	2.3	1.2	0.2	0.6	-0.6	1.5	-0.2	-1.4	-0.1	0.0	-1.1	-0.0	-0.4
Ulcerative Colitis	0.3	0.4	0.8	-0.4	0.7	0.8	-0.9	-0.8	-0.4	0.5	0.7	0.9	-0.3	-0.8	0.0
Cardiovascular Disease	0.3	0.8	2.4	1.6	0.5	1.0	-1.1	0.5	0.6	0.8	0.1	0.7	1.5	1.4	-0.3
Neuroticism	0.3	0.7	1.9	0.5	-0.9	1.4	-0.8	-0.6	-1.1	0.1	1.2	1.1	-0.6	-0.8	-0.6
Chronotype (morning person)	0.3	0.7	4.8	-0.3	0.5	2.2	-0.0	-0.7	-1.2	-0.2	0.6	0.9	0.6	-0.7	0.4
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.3	0.5	-0.6	-0.9	-0.7	0.8	-1.1	0.7	-0.4	-0.4	0.2	0.8	-0.6
Stomach or abdominal pain in last month	0.3	0.3	1.2	0.9	-1.1	-0.1	-0.4	0.8	-0.4	-0.4	-0.7	-0.6	-0.2	-0.3	-0.8
Medication: Atenolol	0.3	0.4	1.6	-0.1	0.9	1.2	-0.1	-0.4	-0.4	0.9	0.0	0.2	1.3	-0.5	0.1
Past tobacco smoking	0.3	0.5	2.1	1.0	-0.5	-1.5	0.7	-0.1	0.6	-0.8	-0.8	-0.7	0.9	0.2	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.9	0.1	-1.1	-0.2	-0.4	-0.2	-0.7	-0.7	-0.2	-0.3	-1.4	-0.7	-0.9
Alcohol intake versus 10 years previously	0.3	0.4	1.4	-0.2	-1.0	-1.2	-1.1	0.4	-0.8	-0.1	-0.6	-0.2	-0.4	-0.1	-0.7
Father’s age at death	0.3	0.4	0.9	0.3	0.8	0.8	0.5	-0.9	0.0	-0.6	-0.6	-0.5	0.9	-0.4	0.6
Impedance of arm (left)	0.3	1.3	5.6	0.0	-1.6	-0.1	-2.4	0.0	-1.8	-0.6	-0.5	-0.1	-1.7	0.6	-1.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	2.4	-0.6	-1.6	0.5	0.5	0.5	-0.4	-0.9	-0.0	-0.3	-1.5	-0.0	-0.3
Forced vital capacity (FVC), Best measure	0.3	1.1	2.3	1.0	0.0	0.6	1.5	0.4	0.9	-0.9	-1.4	-1.5	1.4	1.2	0.9
Exposure to tobacco smoke outside home	0.3	0.4	1.8	-0.5	-0.4	-0.3	0.3	0.5	0.9	-0.5	0.4	-0.1	-1.1	1.4	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	1.6	-0.2	-0.5	-0.0	0.1	0.3	-0.2	1.0	1.3	1.0	-0.1	-0.7	0.0
Eye problems/disorders: None of the above	0.3	0.4	1.5	-0.8	-0.1	-0.4	-0.2	0.4	-0.5	0.8	1.0	1.2	-0.2	-0.3	-0.2
Leg fat mass (right)	0.3	1.3	3.9	-2.0	0.8	0.8	1.9	0.1	1.2	0.9	1.5	1.3	0.4	-1.1	1.0
Alcohol intake frequency.	0.3	0.8	5.7	0.7	-0.2	-0.3	1.0	2.4	0.3	-0.4	-0.9	-1.2	-0.3	0.7	-0.1
Comparative height size at age 10	0.3	1.5	5.4	2.3	0.7	2.3	0.9	0.1	0.5	-0.2	-0.8	-0.8	1.5	1.3	1.2
Had major operations	0.3	0.3	1.4	0.9	-0.1	-1.0	-0.2	0.6	0.4	-0.5	-0.2	-0.4	0.1	1.2	0.2
Eye problems/disorders: Cataract	0.3	0.4	1.9	-0.2	0.4	-0.0	0.5	1.0	1.4	-0.4	-0.6	-1.1	-0.0	0.2	0.0
Number of self-reported non-cancer illnesses	0.3	0.6	2.5	0.6	0.4	0.4	0.3	1.6	0.5	-0.6	-1.1	-1.1	0.8	0.9	0.3
Miserableness	0.3	0.5	1.3	0.4	-0.2	1.2	0.8	0.1	0.7	-1.1	0.9	0.6	-0.8	0.6	0.1
Commuting to job workplace: Cycle	0.3	0.4	2.2	-1.3	1.5	0.0	0.2	-0.3	-0.5	-0.6	-0.1	0.1	-0.1	-0.8	0.4
Body Mass Index (BMI) (2010)	0.2	0.3	1.1	0.1	-0.2	0.3	-0.6	0.8	-0.1	0.7	1.0	0.9	0.3	0.2	-0.1
Blood Platelet Count	0.2	2.8	16.2	1.8	-0.5	-0.5	1.4	-2.6	-1.8	0.7	1.2	1.3	-4.0	-0.9	0.1
Respiratory disease	0.2	0.6	1.8	-0.4	-0.9	-0.6	1.2	1.4	0.7	0.4	1.0	0.3	-0.8	0.3	-0.2
Lung FVC	0.2	0.9	2.7	-0.3	-0.1	1.1	1.3	-1.6	-1.0	-0.1	1.0	0.9	0.3	-1.5	1.1
Hand grip strength (left)	0.2	0.6	1.7	-0.2	-0.8	0.2	-1.0	0.2	-0.6	-0.6	-1.2	-1.0	-0.3	-1.3	-0.7
Medication: Metformin	0.2	0.3	1.5	0.0	-0.7	-0.9	-0.7	0.0	-0.5	0.4	-0.1	0.0	-0.5	-1.2	-0.7
Forced vital capacity (FVC)	0.2	0.6	1.3	1.1	-0.1	0.8	0.6	0.5	0.9	-1.0	-1.1	-1.0	1.0	0.6	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.4	-0.5	-1.1	-1.6	-0.5	0.9	0.2	-0.3	-0.6	-0.6	0.4	0.1	-1.0
Worrier / anxious feelings	0.2	0.3	1.7	1.3	-0.1	0.9	0.8	-0.1	0.1	0.3	-0.5	-0.6	-0.0	0.3	0.7
Happiness	0.2	0.3	1.1	-0.1	-0.3	0.2	0.3	-0.1	0.8	-0.6	0.6	0.6	0.3	1.0	0.3
Medication: Cholesterol lowering	0.2	0.3	1.2	0.5	0.8	-0.6	-0.2	-0.2	0.2	0.7	-0.4	-0.2	1.1	-0.0	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	2.9	0.7	0.5	0.4	1.2	-0.2	0.2	-0.5	-0.9	-1.0	1.7	0.9	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.1	0.2	0.2	0.9	0.7	-0.7	-1.0	0.7	0.2	0.1	0.4	-0.6	0.4
Hair/balding pattern: Pattern 4	0.2	0.4	3.7	0.2	0.3	-1.9	-0.9	0.3	-0.3	-0.4	-0.5	-0.4	0.2	0.3	-0.4
Peak expiratory flow (PEF)	0.2	0.4	2.3	-0.7	-0.3	-1.5	-0.3	0.1	0.1	0.6	0.2	0.1	-0.1	-1.0	-0.7
Blood clot in the leg (DVT)	0.2	0.3	1.5	-0.3	0.0	-0.9	0.8	0.6	-0.5	1.2	0.3	-0.1	0.5	0.4	0.4
Family relationship satisfaction	0.2	0.3	0.9	-0.5	0.1	-0.9	0.6	-0.2	0.6	-0.4	0.2	-0.0	0.7	0.7	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.8	-0.6	-0.0	-0.9	0.2	0.7	0.3	-0.3	-0.4	-0.4	-0.1	0.8	-0.2
Loneliness, isolation	0.2	0.3	1.1	-0.5	0.3	0.8	0.3	-1.1	-0.1	-0.2	0.7	0.4	0.2	-0.3	0.6
Diabetes diagnosed by doctor	0.2	0.4	2.1	-0.6	-0.1	-0.9	-0.4	0.3	0.1	-0.2	0.1	0.1	-0.8	-1.5	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	1.3	-0.2	-1.0	-1.1	-0.1	0.7	-0.2	0.3	-0.0	-0.3	-0.2	0.1	-0.3
Medication: Gliclazide	0.2	0.2	1.3	-0.1	-0.1	0.1	-0.8	0.1	-0.7	0.1	0.0	0.3	0.1	-1.1	-0.6
Medication: Lisinopril	0.2	0.3	1.4	1.0	0.2	-0.1	-1.2	0.1	0.1	0.6	0.4	0.8	0.4	0.3	-0.4
Diastolic blood pressure, automated reading	0.2	0.5	2.0	0.9	0.2	-0.5	-0.1	1.4	0.6	0.0	0.5	0.4	0.7	1.3	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.0	0.4	-0.1	-0.3	-0.3	1.0	-0.5	0.7	-0.5	-0.5	0.2	0.9	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	1.2	-0.2	-0.3	-1.1	0.4	0.6	-0.8	1.1	0.1	-0.2	-0.0	0.2	-0.1
Heart disease (siblings)	0.2	0.2	1.5	1.2	-0.3	0.0	-0.3	-0.3	-0.7	-0.3	-0.1	-0.2	-0.1	-0.7	-0.3
Mean Putamen Volume	0.1	0.2	0.4	-0.1	-0.7	-0.6	-0.2	0.3	-0.6	-0.1	0.4	0.6	-0.5	-0.0	-0.4
Blood Red Count	0.1	1.0	5.7	0.4	-0.4	2.4	0.4	-1.3	-0.7	-1.3	-1.3	-0.9	-0.1	0.5	0.4
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.6	0.3	0.0	-0.8	-0.4	0.4	-0.5	-0.5	-0.6	-0.5	-0.5	-0.2	-0.8
Hair Pigment	0.1	2.2	8.6	1.3	2.5	0.4	2.2	-0.8	0.3	0.2	0.3	0.2	2.9	0.7	2.5
Tanning	0.1	1.1	3.8	0.7	-0.3	-0.7	-0.2	1.4	1.2	-1.1	-1.9	-1.8	-0.6	1.1	0.2
Diabetes (father)	0.1	0.2	0.9	0.7	-0.3	0.4	0.9	-0.2	0.5	-0.2	-0.2	-0.2	-0.1	0.7	-0.0
Age when periods started (menarche)	0.1	0.4	2.2	0.1	-0.5	-0.3	-0.5	-0.5	-1.5	-0.5	-0.3	0.1	0.3	-0.6	-0.8
Diabetes (self-reported)	0.1	0.1	0.5	-0.5	0.3	-0.5	0.2	-0.1	0.3	0.0	0.3	0.3	0.3	-0.7	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.8	0.0	-0.5	0.6	0.9	0.0	0.4	-0.1	0.6	0.4	-0.6	-0.2	0.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	1.5	0.5	0.2	0.2	0.1	-0.3	0.0	-0.4	-0.8	-0.6	1.2	0.2	0.3
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Medication: Omeprazole	0.0	0.0	0.1	0.1	-0.2	0.2	-0.1	0.2	-0.2	0.3	0.3	0.1	0.4	0.2	-0.1

Hub : Genes

SLC45A4

Models

Trait associations