TWAS hub - DNAJC12

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Muscle Skeletal	0.0528	0.0228	4.3e-04	0.036	NA	0.022	NA	0.018	1.6e-04	NA	0.0027	NA	6.5e-03
2	GTEx	Testis	0.2170	0.0690	7.6e-05	0.151	NA	0.080	NA	0.121	3.1e-07	NA	0.0002	NA	5.2e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Seen doctor (GP) for nerves, anxiety, tension or depression	10.2	15.7	15.8	3.9	4.0
Systolic blood pressure, automated reading	9.0	26.2	34.1	5.8	4.3
Systolic Blood Pressure	7.9	39.3	44.9	6.7	5.8
Fractured/broken bones in last 5 years	7.8	10.1	12.7	-2.7	-3.6
Mineral and other dietary supplements	7.2	9.7	10.2	-3.2	-3.0
Wears glasses or contact lenses	6.7	7.8	8.0	2.7	2.8
Pain type(s) experienced in last month: Hip pain	6.7	8.4	8.7	3.0	2.8
Supplements: Fish oil (including cod liver oil)	6.3	8.2	9.9	3.1	2.6
Average weekly red wine intake	5.6	8.3	11.9	-3.5	-2.2
Blood White Count	5.2	38.7	47.7	-6.9	-5.5
Diastolic blood pressure, automated reading	5.2	16.2	18.1	4.3	3.8
Major Depression (MDD)	4.9	6.0	8.1	1.9	2.9
Chronic bronchitis/emphysema (father)	4.9	5.7	5.9	2.4	2.4
Had menopause	4.8	6.0	8.1	2.8	2.0
Pain all over the body in last month	4.2	4.5	4.5	2.1	2.1
Mouth/teeth dental problems: Loose teeth	4.0	4.8	6.7	2.6	1.7
Long-standing illness, disability or infirmity	3.9	6.0	7.2	2.2	2.7
Diabetes diagnosed by doctor	3.8	6.2	7.2	2.3	2.7
Average weekly champagne plus white wine intake	3.7	5.1	7.5	-2.7	-1.6
Birth weight of first child	3.6	6.5	6.6	-2.5	-2.6
Mouth/teeth dental problems: Bleeding gums	3.6	4.7	4.8	-2.1	-2.2
Illnesses of father: High blood pressure	3.6	4.5	5.3	2.3	1.9
Chronotype (morning person)	3.4	7.8	9.5	-3.1	-2.5
Guilty feelings	3.4	5.2	7.0	-2.7	-1.8
Happiness	3.3	4.0	4.1	2.0	2.0
Irritability	3.3	5.5	9.8	-3.1	-1.1
Eye problems/disorders: Glaucoma	3.1	3.7	5.6	1.3	2.4
Age started oral contraceptive pill	3.1	3.9	6.2	1.2	2.5
Medication: Omeprazole (e.g. Zanprol)	3.1	3.8	6.4	2.5	1.1
Body Mass Index (BMI) (2010)	3.0	4.1	6.4	-2.5	-1.3
Type 2 Diabetes (T2D) (2018)	3.0	5.6	6.7	2.6	2.1
Medication: Metformin	2.9	4.1	5.6	2.4	1.6
Qualifications: College or University degree	2.8	8.8	16.2	-4.0	-1.2
Eye problems/disorders: Cataract	2.8	3.2	4.8	-2.2	-1.2
Ever had hysterectomy (womb removed)	2.7	3.0	3.4	1.6	1.8
Alzheimer’s Disease (including proxy)	2.6	3.8	5.3	-1.5	-2.3
Illnesses of siblings: Diabetes	2.5	3.0	3.1	1.7	1.8
Vitamin and mineral supplements	2.4	3.3	3.7	-1.7	-1.9
Breast Cancer	2.3	5.5	8.1	1.7	2.8
Frequency of unenthusiasm / disinterest in last 2 weeks	2.3	3.1	3.8	1.9	1.5
Medication: Paracetamol	2.3	3.8	6.2	2.5	1.2
Diabetes (self-reported)	2.2	3.4	4.8	1.4	2.2
Medication: Allopurinol	2.2	3.0	3.8	2.0	1.5
Cholesterol lowering medication	2.2	3.3	4.1	2.0	1.6
Medication: Omeprazole	2.1	2.5	4.5	2.1	0.7
Mean Putamen Volume	2.0	2.3	3.2	1.2	1.8
Mouth/teeth dental problems: Dentures	2.0	3.4	3.4	1.9	1.8
Number of treatments/medications taken	1.9	3.5	4.3	2.1	1.6
Diabetes (mother)	1.9	2.4	3.3	1.8	1.2
Illness, injury, bereavement, stress in last 2 years	1.9	2.3	3.2	-1.8	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.2	4.3	2.1	0.2
Loneliness, isolation	1.9	2.7	2.7	1.6	1.6
Supplements: Calcium	1.9	2.1	2.4	1.5	1.4
Alzheimer’s Disease (in mother)	1.8	2.1	3.3	-0.9	-1.8
Number of self-reported non-cancer illnesses	1.8	3.2	4.3	1.4	2.1
Medication: Ibuprofen	1.7	2.0	2.3	-1.3	-1.5
Medication: Gliclazide	1.7	1.9	3.2	0.8	1.8
Hearing difficulty/problems: Yes	1.6	2.4	3.2	1.8	1.3
Taking other prescription medications	1.6	2.5	3.4	1.3	1.9
Qualifications: None of the above	1.6	3.4	5.0	2.2	1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.1	3.6	0.8	1.9
Fed-up feelings	1.5	2.7	3.8	1.3	1.9
Multivitamins +/- minerals	1.5	1.9	2.8	1.7	1.0
Ever taken oral contraceptive pill	1.5	1.7	3.4	0.0	-1.8
Medication: Blood pressure	1.5	2.8	3.4	1.8	1.5
Medication: Paracetamol	1.5	2.3	3.8	2.0	0.8
Blood Platelet Count	1.4	16.6	20.4	-4.5	-3.6
Worry too long after embarrassment	1.4	2.3	4.4	-2.1	-0.4
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	2.0	1.0	1.4
Medication: Simvastatin	1.3	1.9	2.6	1.6	1.1
Pulse rate	1.3	2.1	3.0	-1.7	-1.1
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	2.4	-0.9	-1.6
Medication for pain relief, constipation, heartburn	1.3	2.2	4.2	-2.1	-0.4
Migraine (self-reported)	1.3	1.7	2.3	-1.5	-1.0
Medication: Seretide 50 evohaler	1.3	1.5	2.9	-1.7	-0.4
Hypertension (Self-reported)	1.3	3.6	4.3	2.1	1.7
Medication for cholesterol	1.3	2.0	2.5	-1.6	-1.3
Frequency of depressed mood in last 2 weeks	1.2	1.6	2.7	0.7	1.6
High blood pressure	1.2	3.3	4.2	2.0	1.6
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.8	2.6	1.1	1.6
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.4	4.7	0.4	2.2
Alzheimer’s Disease (in father)	1.1	1.1	1.2	-1.1	-1.0
Rheumatoid Arthritis	1.1	1.5	1.8	1.1	1.3
Allergy or Eczema	1.1	2.9	5.7	0.4	2.4
Cardiovascular Disease	1.1	3.8	4.4	1.8	2.1
Hypothyroidism (self reported)	1.1	2.5	3.6	1.9	1.1
Qualifications: CSEs or equivalent	1.1	1.4	2.6	1.6	0.5
Supplements: Glucosamine	1.1	1.5	1.8	1.1	1.3
Financial difficulties in last 2 years	1.1	1.5	2.7	1.6	0.6
Hypothyroidism/myxoedema (self-reported)	1.1	2.1	2.3	1.5	1.3
Qualifications: nursing, teaching	1.1	1.7	1.7	-1.3	-1.3
Unable to work because of sickness or disability	1.1	1.5	1.7	1.3	1.1
Prostate Cancer	1.0	1.4	1.4	1.2	1.2
Coronary Artery Disease (CAD)	1.0	1.2	2.5	-0.1	-1.6
Hip circumference	1.0	4.2	4.9	2.2	1.9
Pulse rate, automated reading	1.0	3.1	5.3	-2.3	-0.9
Comparative height size at age 10	1.0	5.5	10.8	0.4	3.3
Smoking status: Previous	1.0	1.5	2.7	1.6	-0.5
Asthma (self-reported)	1.0	1.9	2.5	-1.6	-1.1
Mother’s age at death	1.0	1.2	2.4	0.0	1.6
Tinnitus: Yes, now most or all of the time	1.0	1.2	2.1	1.5	0.5
Vascular/heart problems diagnosed by doctor	1.0	2.9	3.7	-1.9	-1.4
Bipolar Disorder (2018)	0.9	1.4	2.4	-1.5	0.6
Waist Hip Ratio (WHR)	0.9	3.9	4.5	-1.8	-2.1
Past tobacco smoking	0.9	1.6	2.3	-1.5	0.9
Fluid intelligence score	0.9	1.8	3.3	-1.8	-0.6
Pulse wave reflection index	0.9	1.1	2.0	1.4	0.5
Glaucoma (self-reported)	0.9	1.1	2.1	0.3	1.4
Neck or shoulder pain in last month	0.9	1.3	2.1	-0.7	-1.4
Handedness (chirality/laterality): Left-handed	0.9	1.1	1.3	-1.1	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	1.8	0.6	1.3
Ever smoked	0.9	1.5	2.6	1.6	-0.6
Average weekly beer plus cider intake	0.9	1.3	2.0	1.4	-0.8
Schizophrenia vs Biploar Disorder	0.8	1.0	1.8	1.4	-0.4
HbA1C	0.8	0.8	1.4	1.2	-0.6
Neuroticism (2016)	0.8	1.2	1.8	-1.4	-0.7
Medication: Co-codamol	0.8	0.9	1.7	1.3	0.3
Nervous feelings	0.8	1.5	2.8	0.5	1.7
Asthma	0.8	1.6	1.8	-1.3	-1.2
Medication: Lansoprazole	0.8	0.9	1.7	1.3	0.2
Angina (self-reported)	0.8	1.0	1.8	1.3	0.5
Overall health rating	0.8	1.6	2.5	1.6	0.9
Osteoporosis (self-reported)	0.8	1.0	1.8	0.3	1.4
High cholesterol (Self-reported)	0.8	1.3	1.9	1.4	0.9
Leg fat percentage (left)	0.8	2.9	5.8	2.4	-0.1
Bipolar Disorder (2011)	0.7	0.6	1.1	-1.0	-0.4
Townsend deprivation index at recruitment	0.7	0.9	1.3	1.1	0.8
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	1.5	-1.2	-0.3
Worrier / anxious feelings	0.7	1.3	2.7	0.1	1.6
Health satisfaction	0.7	1.0	1.1	0.9	1.0
Heart disease (mother)	0.7	0.9	1.4	1.2	0.6
Supplements: Vitamin C	0.7	0.8	1.2	0.6	1.1
Financial situation satisfaction	0.7	0.9	1.2	1.1	0.8
Type 2 Diabetes (T2D) (2012)	0.6	0.6	0.8	0.7	0.9
Blood Red Count	0.6	5.9	6.5	-2.3	-2.5
Relative age of first facial hair	0.6	1.2	1.2	1.1	1.1
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.5	-0.2	1.2
Maternal smoking around birth	0.6	0.9	1.5	1.2	-0.5
Hayfever, allergic rhinitis or eczema	0.6	1.4	2.0	-0.8	1.4
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.3	1.1	0.4
Number of incorrect matches in round	0.6	1.0	1.4	-1.2	-0.8
Alcohol usually taken with meals	0.6	0.9	1.6	-1.3	-0.5
Trunk fat-free mass	0.6	3.3	6.5	0.2	2.5
Number of live births	0.6	0.8	1.6	1.2	0.1
Qualifications: A levels/AS levels or equivalent	0.6	1.3	2.4	-1.5	0.4
Depression (self-reported)	0.6	0.7	1.2	0.5	1.1
Trunk predicted mass	0.6	3.2	6.3	0.2	2.5
Length of working week for main job	0.6	0.7	0.7	-0.8	-0.8
Exposure to tobacco smoke at home	0.6	0.6	0.8	0.7	0.9
Tense / ‘highly strung’	0.6	0.9	1.2	-1.1	0.8
Leg fat percentage (right)	0.6	2.3	4.7	2.2	-0.2
Exposure to tobacco smoke outside home	0.6	0.8	1.5	-1.2	-0.2
Commuting to job workplace: Walk	0.6	0.6	1.0	-1.0	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	2.4	1.6	0.2
Arm fat-free mass (left)	0.6	3.0	5.4	0.7	2.3
Arm predicted mass (left)	0.6	3.1	5.8	0.6	2.4
Depression (Nagel 2018)	0.5	0.8	0.8	0.9	0.8
Neuroticism (Nagel 2018)	0.5	1.3	2.5	-1.6	-0.3
HDL Cholesterol	0.5	0.8	1.2	-1.1	-0.6
Schizophrenia (2014)	0.5	1.2	1.8	-0.7	-1.3
Lung FVC	0.5	2.5	3.7	1.9	-1.1
Average weekly spirits intake	0.5	0.6	1.1	-0.1	-1.1
Sensitivity / hurt feelings	0.5	0.8	1.5	-1.2	0.4
Relative age voice broke	0.5	0.8	1.1	1.1	0.7
Hair/balding pattern: Pattern 2	0.5	0.6	0.6	0.7	0.8
Medication: Ramipril	0.5	0.6	0.8	0.7	0.9
Illnesses of siblings	0.5	0.6	1.2	-1.1	-0.2
Neuroticism score	0.5	1.0	1.3	-0.8	1.2
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.4	0.5	1.2
Eye problems/disorders: None of the above	0.5	0.6	1.1	1.1	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.1	1.1	0.3
Medication: Aspirin	0.5	0.6	1.0	1.0	0.5
Whole body fat-free mass	0.5	2.7	5.3	0.0	2.3
Mood swings	0.5	0.9	1.6	-0.4	1.3
Alcohol drinker status: Never	0.5	0.6	0.8	0.6	0.9
Alcohol drinker status: Previous	0.5	0.6	0.9	1.0	0.6
Pack years of smoking	0.5	0.7	1.3	-1.1	-0.2
Impedance of whole body	0.5	2.4	4.3	-0.7	-2.1
Angina	0.4	0.6	1.1	1.0	0.3
Pack years adult smoking proportion	0.4	0.7	1.3	-1.1	-0.1
Impedance of leg (right)	0.4	1.8	3.6	0.2	-1.9
Age when periods started (menarche)	0.4	0.9	1.8	0.1	-1.4
Medication: Levothyroxine sodium	0.4	0.6	0.7	0.8	0.8
Sitting height	0.4	2.9	5.7	0.4	2.4
Impedance of leg (left)	0.4	2.0	3.8	0.4	-1.9
Heart attack	0.4	0.5	0.7	-0.8	-0.6
Allergy	0.4	0.8	1.4	0.5	-1.2
Noisy workplace	0.4	0.5	0.9	1.0	0.0
Impedance of arm (left)	0.4	1.7	2.6	-0.9	-1.6
Birth weight	0.4	0.9	1.8	-1.3	-0.1
Leg fat mass (right)	0.4	1.4	2.7	1.6	0.4
Knee pain experienced in last month	0.4	0.6	1.1	1.0	-0.3
Illnesses of father: Heart disease	0.4	0.5	1.0	-0.3	-1.0
Breast cancer (self-reported)	0.4	0.4	0.7	0.8	0.4
Smoking status: Current	0.4	0.6	0.8	-0.6	-0.9
Whole body water mass	0.4	2.5	5.0	-0.1	2.2
Leg predicted mass (right)	0.4	1.9	3.7	-0.4	1.9
Commuting to job workplace: Public transport	0.4	0.5	0.9	-1.0	0.1
Basal metabolic rate	0.4	2.4	4.7	0.3	2.2
Number of operations (self-reported)	0.4	0.6	1.1	1.1	0.4
Pain experienced in last month	0.4	0.6	1.2	-0.2	1.1
Heart disease (siblings)	0.4	0.4	0.8	0.9	-0.1
Leg fat mass (left)	0.4	1.7	3.2	1.8	0.5
Bipolar Disorder or Schizophrenia	0.3	0.8	1.6	-1.3	-0.1
Depressed Affect (Nagel 2018)	0.3	0.6	1.0	0.4	1.0
Intelligence (Savage-Jansen 2018)	0.3	0.8	1.1	-1.1	0.7
Reaction Time	0.3	0.6	0.7	-0.8	-0.7
LDL Cholesterol	0.3	0.4	0.9	-0.9	-0.1
Lupus	0.3	0.4	0.8	-0.3	-0.9
Height	0.3	4.9	9.7	0.4	3.1
Leg fat-free mass (left)	0.3	1.6	3.0	-0.4	1.7
Medication: Atenolol	0.3	0.4	0.8	-0.2	0.9
Leg predicted mass (left)	0.3	1.5	2.8	-0.4	1.7
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.8	-0.9	-0.2
Weight	0.3	1.7	2.4	1.0	1.6
Prospective memory result	0.3	0.4	0.5	0.6	0.7
Standing height	0.3	3.3	6.4	-0.5	2.5
Peak expiratory flow (PEF)	0.3	0.6	1.1	1.1	-0.2
Gout (self-reported)	0.3	0.4	0.7	0.8	0.2
High blood pressure (siblings)	0.3	0.4	0.8	0.9	-0.0
Body fat percentage	0.3	1.3	2.6	1.6	-0.1
Arm fat-free mass (right)	0.3	1.4	2.7	-0.0	1.7
Comparative body size at age 10	0.3	0.7	1.0	-1.0	-0.7
Age at first live birth	0.3	0.5	1.0	-1.0	-0.2
Whole body fat mass	0.3	1.1	2.0	1.4	0.5
Arm predicted mass (right)	0.3	1.6	3.1	0.2	1.8
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.6	0.8	-0.2
Leg fat-free mass (right)	0.3	1.8	3.5	-0.4	1.9
Friendships satisfaction	0.3	0.3	0.7	-0.8	0.2
Arm fat mass (left)	0.3	1.0	1.6	1.3	0.7
Miserableness	0.3	0.5	1.0	-0.1	1.0
Ever depressed for a whole week	0.3	0.4	0.6	0.7	0.5
Myopia	0.3	0.4	0.8	-0.9	-0.1
Basal cell carcinoma (self-reported)	0.3	0.3	0.6	0.8	0.3
Heart attack/myocardial infarction (self-reported)	0.3	0.3	0.5	-0.7	-0.5
Worry (Nagel 2018)	0.2	0.4	0.7	-0.3	0.8
Ovarian Cancer	0.2	0.3	0.3	-0.5	0.5
Triglycerides	0.2	0.4	0.7	0.2	-0.9
Smoking Status	0.2	0.4	0.5	0.7	-0.6
Neuroticism	0.2	0.4	0.5	-0.7	0.5
Hair Pigment	0.2	6.5	9.4	-1.9	-3.1
Supplements: Zinc	0.2	0.2	0.2	0.5	0.4
Severe depression (siblings)	0.2	0.2	0.5	-0.1	0.7
Trunk fat percentage	0.2	0.8	1.6	1.3	-0.2
Current tobacco smoking	0.2	0.3	0.3	-0.6	-0.5
Serious illness, injury or assault to yourself	0.2	0.3	0.3	0.5	0.5
High blood pressure (mother)	0.2	0.3	0.5	0.3	0.7
Body mass index (BMI)	0.2	1.0	1.8	1.4	0.5
Trunk fat mass	0.2	0.7	1.3	1.1	0.4
Forced vital capacity (FVC)	0.2	0.9	1.5	1.2	0.5
Impedance of arm (right)	0.2	0.9	1.4	-0.7	-1.2
Arm fat percentage (right)	0.2	0.8	1.5	1.2	0.1
Alcohol intake versus 10 years previously	0.2	0.2	0.4	0.7	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	0.6	-0.2
Medication: Cholesterol lowering	0.2	0.3	0.6	0.7	0.0
Arm fat mass (right)	0.2	0.9	1.4	1.2	0.7
Breastfed as a baby	0.2	0.3	0.4	-0.6	-0.5
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.4	-0.1	-0.6
Number of full brothers	0.2	0.2	0.4	-0.2	-0.7
Wheeze or whistling in the chest in last year	0.2	0.3	0.6	0.2	0.8
Pulse wave peak to peak time	0.2	0.2	0.4	0.2	0.6
Shortness of breath walking on level ground	0.2	0.2	0.3	-0.5	-0.4
Alcohol intake frequency.	0.2	0.6	1.1	0.1	1.1
Chest pain or discomfort	0.2	0.3	0.6	0.8	0.3
Age at last live birth	0.2	0.3	0.4	-0.7	-0.4
Family relationship satisfaction	0.2	0.2	0.3	0.4	0.5
Arm fat percentage (left)	0.2	0.7	1.4	1.2	-0.1
Osteoarthritis (self-reported)	0.2	0.2	0.5	0.7	0.2
Medication: Aspirin	0.2	0.3	0.4	0.6	0.4
Commuting to job workplace: Cycle	0.2	0.3	0.4	-0.4	0.6
Schizophrenia (2018)	0.1	0.3	0.5	-0.4	-0.7
Crohns Disease (2017)	0.1	0.3	0.3	0.5	0.6
Irritable Bowel Disease (IBD)	0.1	0.2	0.4	0.6	0.1
Ulcerative Colitis (UC)	0.1	0.2	0.3	0.5	-0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.4	0.7	-0.0	0.8
Fasting Glucose	0.1	0.1	0.2	-0.2	-0.5
Primary Biliary Cirrhosis	0.1	0.2	0.2	0.4	-0.4
Ulcerative Colitis	0.1	0.1	0.2	0.0	-0.4
Blood Eosinophil Count	0.1	0.4	0.5	-0.7	-0.6
BMI	0.1	0.5	0.9	-0.3	-0.9
Lung FEV1/FVC ratio	0.1	0.6	0.8	-0.9	-0.6
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.1	-0.3	0.3
Diabetes (father)	0.1	0.1	0.2	0.4	-0.0
Average weekly fortified wine intake	0.1	0.1	0.2	-0.5	0.2
Stomach or abdominal pain in last month	0.1	0.1	0.1	0.2	-0.3
Waist circumference	0.1	0.2	0.5	0.7	0.1
Hearing difficulty/problems with background noise	0.1	0.2	0.3	-0.3	-0.6
Time employed in main current job	0.1	0.1	0.2	0.2	0.5
Father’s age at death	0.1	0.1	0.2	-0.5	0.1
Falls in the last year	0.1	0.1	0.2	0.2	-0.4
Hair/balding pattern: Pattern 3	0.1	0.1	0.2	-0.4	0.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.6	0.7	0.1
Lung cancer (father)	0.1	0.1	0.1	0.4	0.1
Illnesses of mother	0.1	0.1	0.1	-0.3	0.3
Pulse wave Arterial Stiffness index	0.1	0.2	0.2	-0.3	-0.5
Hair/balding pattern: Pattern 4	0.1	0.3	0.3	-0.6	-0.5
Loud music exposure frequency	0.1	0.2	0.2	-0.4	-0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.2	0.3	0.5
Blood clot in the leg (DVT)	0.1	0.1	0.2	0.4	0.1
Headache pain in last month	0.1	0.3	0.3	-0.4	-0.6
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.2	-0.0	-0.5
Medication: Amlodipine	0.1	0.1	0.3	0.2	-0.5
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.2	-0.3	-0.4
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.1	0.3	0.1
Number of children fathered	0.1	0.1	0.1	0.4	-0.1
Medication: Blood pressure	0.1	0.2	0.2	-0.4	0.5
Mean time to correctly identify matches	0.1	0.1	0.2	-0.2	-0.5
Number of full sisters	0.1	0.1	0.2	0.5	-0.2
Suffer from ‘nerves’	0.1	0.1	0.2	0.1	0.5
Leg pain on walking	0.1	0.1	0.2	0.4	0.2
Ever had bowel cancer screening	0.1	0.1	0.2	-0.2	0.4
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.2	-0.4	-0.3
Hearing aid user	0.1	0.1	0.1	0.3	-0.1
Medication: Bendroflumethiazide	0.1	0.2	0.3	-0.2	0.6
Risk taking	0.1	0.2	0.4	-0.0	-0.6
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.1	0.2	0.3
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.1	0.3	-0.3
Age at First Birth	0.0	0.0	0.1	0.0	0.3
Crohns Disease (2012)	0.0	0.1	0.1	-0.3	0.2
Heel T-Score	0.0	0.3	0.5	0.7	0.3
Respiratory disease	0.0	0.1	0.1	-0.3	0.3
Tanning	0.0	0.1	0.2	0.5	-0.2
Hand grip strength (left)	0.0	0.1	0.2	0.2	0.5
Ever used hormone-replacement therapy (HRT)	0.0	0.1	0.1	-0.2	-0.3
Medication for hormone replacement therapy	0.0	0.0	0.1	0.2	0.0
Hand grip strength (right)	0.0	0.1	0.2	-0.4	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.0	0.0	0.1	0.0
Had other major operations	0.0	0.0	0.0	-0.0	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.1	-0.0	0.3
Ever unenthusiastic/disinterested for a whole week	0.0	0.1	0.1	0.3	0.0
Mouth/teeth dental problems	0.0	0.0	0.0	-0.2	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.3	0.2	-0.5
Forced vital capacity (FVC), Best measure	0.0	0.0	0.1	0.3	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.0	0.0	-0.1	0.2
Emphysema/chronic bronchitis	0.0	0.0	0.0	-0.1	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.0	-0.2	-0.1
Had major operations	0.0	0.0	0.1	0.1	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.0	-0.1	-0.2
Back pain experienced in last month	0.0	0.0	0.0	-0.1	-0.1
Illnesses of father: None of the above (group 1)	0.0	0.0	0.0	-0.2	-0.1
Medication: Lisinopril	0.0	0.0	0.1	-0.2	0.0
Medication: Atorvastatin	0.0	0.0	0.1	0.3	0.1

Hub : Genes

DNAJC12

Models

Trait associations