Best TWAS P=2.06e-11 · Best GWAS P=3.18e-14 conditioned to 9.67e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ARHGAP42 | 0.08 | 0.03 | enet | 14 | 0.05 | 2.8e-06 | -4.7 | -6.7 | 2.1e-11 | -0.47 | 0.64 | 0.35 | TRUE |
| 2 | GTEx | Artery Aorta | ARHGAP42 | 0.22 | 0.15 | enet | 18 | 0.19 | 1.7e-10 | -5.0 | -5.4 | 7.5e-08 | -0.35 | 0.83 | 0.16 | FALSE |
| 3 | GTEx | Nerve Tibial | YAP1 | 0.09 | 0.07 | lasso | 4 | 0.05 | 1.5e-04 | -5.4 | -5.5 | 4.0e-08 | -0.05 | 0.04 | 0.95 | FALSE |
| 4 | GTEx | Testis | RP11-864G5.3 | 0.15 | 0.18 | lasso | 1 | 0.15 | 2.5e-07 | -5.6 | -5.6 | 1.8e-08 | -0.02 | 0.02 | 0.98 | TRUE |