TWAS
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About
Usage
Models
Genes
Traits
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Traits
:
Blood White Count
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chr11:99,859,184-102,802,722
Best TWAS P=2.06e-11 · Best GWAS P=3.18e-14 conditioned to 9.67e-07
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
ARHGAP42
0.08
0.03
enet
14
0.05
2.8e-06
-4.7
-6.7
2.1e-11
-0.47
0.64
0.35
TRUE
4
GTEx
Testis
RP11-864G5.3
0.15
0.18
lasso
1
0.15
2.5e-07
-5.6
-5.6
1.8e-08
-0.02
0.02
0.98
TRUE
3
GTEx
Nerve Tibial
YAP1
0.09
0.07
lasso
4
0.05
1.5e-04
-5.4
-5.5
4.0e-08
-0.05
0.04
0.95
FALSE
2
GTEx
Artery Aorta
ARHGAP42
0.22
0.15
enet
18
0.19
1.7e-10
-5.0
-5.4
7.5e-08
-0.35
0.83
0.16
FALSE