Best TWAS P=2.37e-10 · Best GWAS P=1.07e-10 conditioned to 2.53e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | TPCN2 | 0.19 | 0.10 | lasso | 4 | 0.10 | 3.0e-06 | 4.6 | 5.5 | 3.3e-08 | 0.06 | 0.80 | 0.12 | TRUE |
| 2 | GTEx | Vagina | RP11-554A11.9 | 0.49 | 0.11 | lasso | 6 | 0.12 | 9.5e-04 | 5.5 | 5.2 | 1.7e-07 | -0.07 | 0.08 | 0.11 | TRUE |
| 3 | NTR | Blood | ORAOV1 | 0.04 | 0.02 | lasso | 2 | 0.02 | 2.3e-07 | 6.3 | -6.3 | 2.4e-10 | 0.22 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | CCND1 | 0.05 | 0.03 | lasso | 2 | 0.02 | 8.8e-03 | 5.7 | -5.6 | 1.7e-08 | 0.14 | 0.01 | 0.68 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | ORAOV1 | 0.04 | 0.00 | blup | 49 | 0.03 | 1.2e-03 | 5.2 | -5.5 | 4.2e-08 | 0.18 | 0.01 | 0.71 | FALSE |