TWAS
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Usage
Models
Genes
Traits
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Traits
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Blood White Count
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chr11:68,118,563-70,179,848
Best TWAS P=2.37e-10 · Best GWAS P=1.07e-10 conditioned to 2.53e-07
68M
68.5M
69M
69.5M
70M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
NTR
Blood
ORAOV1
0.04
0.02
lasso
2
0.02
2.3e-07
6.3
-6.3
2.4e-10
0.22
0.01
0.99
TRUE
1
GTEx
Skin Not Sun Exposed Suprapubic
TPCN2
0.19
0.10
lasso
4
0.10
3.0e-06
4.6
5.5
3.3e-08
0.06
0.80
0.12
TRUE
2
GTEx
Vagina
RP11-554A11.9
0.49
0.11
lasso
6
0.12
9.5e-04
5.5
5.2
1.7e-07
-0.07
0.08
0.11
TRUE
4
The Cancer Genome Atlas
Thyroid Carcinoma
CCND1
0.05
0.03
lasso
2
0.02
8.8e-03
5.7
-5.6
1.7e-08
0.14
0.01
0.68
FALSE
5
The Cancer Genome Atlas
Thyroid Carcinoma
ORAOV1
0.04
0.00
blup
49
0.03
1.2e-03
5.2
-5.5
4.2e-08
0.18
0.01
0.71
FALSE