[Hub]/) : Traits : Blood White Count :

chr13:113,378,882-115,106,996

Best TWAS P=1.29e-18 · Best GWAS P=3.34e-19 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DCUN1D2 0.04 0.02 lasso 6 0.03 4.0e-04 8.0 -7.5 6.5e-14 -0.84 0.18 0.69 FALSE
2 GTEx Brain Caudate basal ganglia DCUN1D2 0.18 -0.01 enet 11 0.00 4.7e-01 3.6 -5.3 8.9e-08 -0.74 0.05 0.26 FALSE
3 GTEx Brain Cerebellar Hemisphere TMCO3 0.17 0.07 lasso 11 0.11 8.9e-04 8.1 8.5 2.6e-17 0.82 0.05 0.69 TRUE
4 GTEx Brain Hippocampus TMEM255B 0.23 0.04 enet 24 0.05 2.6e-02 -1.1 6.0 2.6e-09 0.26 0.04 0.47 FALSE
5 GTEx Muscle Skeletal TMCO3 0.25 0.18 lasso 6 0.23 2.7e-22 8.3 8.2 1.8e-16 0.91 0.01 0.99 FALSE
6 GTEx Nerve Tibial TMCO3 0.09 0.06 lasso 3 0.04 4.5e-04 9.0 -8.8 1.3e-18 -1.00 0.00 0.99 TRUE
7 GTEx Thyroid TMCO3 0.22 0.12 lasso 2 0.13 4.0e-10 7.0 -6.3 3.1e-10 -0.75 0.42 0.57 FALSE
8 METSIM Adipose ADPRHL1 0.07 0.00 bslmm 392 0.02 4.6e-04 -6.9 5.7 1.4e-08 0.26 0.04 0.47 TRUE
9 The Cancer Genome Atlas Brain Lower Grade Glioma DCUN1D2 0.03 0.02 blup 79 0.04 2.2e-05 8.4 -6.9 5.6e-12 -0.82 0.04 0.95 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma RASA3 0.04 0.01 blup 90 0.01 7.2e-03 4.4 6.4 1.2e-10 0.02 0.09 0.13 TRUE
11 The Cancer Genome Atlas Brain Lower Grade Glioma TMCO3 0.05 0.04 blup 78 0.04 5.6e-05 8.2 -6.7 2.6e-11 -0.85 0.03 0.97 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma GRK1 0.04 0.02 blup 36 0.02 7.7e-04 7.1 7.3 2.6e-13 0.71 0.00 0.98 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma GRK1 0.23 0.19 enet 9 0.24 1.1e-22 4.7 6.3 3.3e-10 0.60 1.00 0.00 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma TMCO3 0.27 0.04 enet 14 0.13 9.1e-13 7.0 -6.9 4.1e-12 -0.74 0.00 1.00 FALSE