Hub : Genes

TMCO3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.3090 0.0510 1.6e-15 0.134 0.144 0.232 0.240 0.190 4.7e-16 4.1e-17 6.9e-28 7.8e-29 1.4e-22
2 GTEx Adipose Subcutaneous 0.1200 0.0480 2.8e-03 0.105 NA 0.084 NA 0.115 6.2e-09 NA 2.2e-07 NA 1.3e-09
3 GTEx Artery Aorta 0.1270 0.0460 2.4e-03 0.012 NA 0.056 NA 0.056 7.1e-02 NA 5.1e-04 NA 4.9e-04
4 GTEx Artery Tibial 0.1030 0.0470 6.0e-03 0.051 NA 0.025 NA 0.039 6.8e-05 NA 4.6e-03 NA 4.6e-04
5 GTEx Brain Cerebellar Hemisphere 0.1750 0.0740 4.5e-03 0.072 NA 0.092 NA 0.111 6.6e-03 NA 2.4e-03 NA 8.9e-04
6 GTEx Brain Cortex 0.2380 0.0970 7.3e-03 0.165 NA 0.044 NA 0.100 2.6e-05 NA 2.3e-02 NA 1.0e-03
7 GTEx Esophagus Muscularis 0.1210 0.0460 1.7e-03 0.045 NA 0.162 NA 0.146 9.7e-04 NA 4.5e-10 NA 3.6e-09
8 GTEx Muscle Skeletal 0.2472 0.0511 5.6e-17 0.179 NA 0.193 NA 0.230 2.8e-17 NA 1.3e-18 NA 2.7e-22
9 GTEx Nerve Tibial 0.0865 0.0343 3.9e-04 0.057 NA 0.031 NA 0.044 6.8e-05 NA 2.7e-03 NA 4.5e-04
10 GTEx Thyroid 0.2160 0.0650 5.9e-06 0.120 NA 0.121 NA 0.130 2.0e-09 NA 1.7e-09 NA 4.0e-10
11 YFS Blood 0.2765 0.0360 0.0e+00 0.015 0.091 0.131 0.138 0.130 7.7e-06 2.4e-28 1.3e-40 7.2e-43 3.7e-40
12 TCGA Kidney Renal Clear Cell Carcinoma 0.1211 0.0593 8.0e-03 0.038 0.006 0.024 NA 0.025 3.7e-05 5.7e-02 8.8e-04 NA 7.0e-04
13 TCGA Brain Lower Grade Glioma 0.0479 0.0278 5.2e-06 0.037 0.036 0.017 NA 0.034 4.2e-05 5.6e-05 3.9e-03 NA 8.6e-05
14 TCGA Prostate Adenocarcinoma 0.0679 0.0371 1.7e-03 0.009 0.021 0.008 NA 0.014 3.2e-02 2.4e-03 4.5e-02 NA 1.1e-02
15 TCGA Thyroid Carcinoma 0.2710 0.0760 8.5e-12 0.041 0.115 0.132 NA 0.101 6.4e-05 2.9e-11 9.1e-13 NA 5.0e-10

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bipolar Disorder (2018) 0.8 1.3 5.4 2.3 0.0 1.3 -1.2 -0.1 1.1 0.9 0.6 -1.1 -1.4 -0.6 -1.2 -0.4 0.8 -1.5
Bipolar Disorder or Schizophrenia 0.5 1.3 4.4 0.1 -1.6 0.6 -0.9 -0.9 1.8 0.1 -0.3 0.2 0.9 2.1 -1.8 0.7 1.0 1.5
Depressed Affect (Nagel 2018) 0.4 0.9 2.6 0.8 1.4 1.4 1.3 -0.3 1.4 1.1 -0.2 -0.0 0.5 -0.4 0.8 0.8 1.6 0.0
Depression (Nagel 2018) 0.8 1.3 3.0 0.5 0.5 1.0 1.0 1.7 -0.4 1.3 1.7 -1.7 -1.1 -0.5 -0.0 -1.3 -0.1 -1.6
Intelligence (Savage-Jansen 2018) 1.1 3.4 8.3 -0.9 0.7 -1.0 -0.4 -2.9 1.4 -1.3 -2.5 2.5 2.8 0.7 1.0 2.6 1.3 2.4
Neuroticism (Nagel 2018) 1.3 3.2 7.7 2.2 2.8 2.7 2.4 -0.0 1.3 2.3 -0.1 0.0 -0.5 -2.1 2.1 0.8 1.8 -1.4
Schizophrenia (2018) 1.1 2.3 9.6 -1.8 -0.5 -0.1 0.1 -1.1 1.4 -0.4 -0.8 1.2 2.5 3.1 -0.3 1.2 0.7 2.9
Schizophrenia vs Biploar Disorder 0.8 1.1 3.2 -1.4 1.2 0.5 1.8 -0.1 0.7 0.4 -0.4 0.4 1.3 1.3 1.4 0.7 1.4 0.9
Worry (Nagel 2018) 1.9 4.1 11.4 2.6 3.4 2.5 2.8 -0.7 0.9 2.1 -0.1 0.0 -0.9 -2.9 2.7 0.9 1.5 -1.8
Alzheimer’s Disease (in mother) 1.0 1.2 5.1 -1.1 -1.2 -0.7 -1.1 -0.7 1.3 -0.7 -0.3 0.5 1.0 2.3 -1.3 0.6 0.9 1.1
Alzheimer’s Disease (in father) 0.8 0.8 1.8 -0.3 -0.4 -0.9 -0.9 0.5 -1.3 -1.0 0.9 -0.5 -1.3 0.1 -0.9 -1.1 -1.0 -1.2
Alzheimer’s Disease (including proxy) 0.5 0.7 3.1 -1.1 -1.0 -0.6 -1.0 -0.2 0.5 -0.8 0.4 -0.3 -0.2 1.8 -1.5 -0.3 0.3 0.1
Crohns Disease (2017) 0.5 1.1 4.4 -1.1 -0.8 0.2 -0.3 0.9 -0.2 -0.1 1.3 -1.4 -0.7 2.1 -1.4 -1.3 0.3 -1.3
Irritable Bowel Disease (IBD) 0.1 0.2 1.8 0.0 -0.3 -0.4 -0.5 0.0 -0.0 -0.2 0.0 0.1 0.0 0.1 -0.3 0.0 0.3 -1.4
Ulcerative Colitis (UC) 0.4 0.7 2.5 -0.2 0.1 -0.9 -0.5 -1.2 0.1 -0.7 -1.3 1.6 1.1 -0.3 0.5 1.3 0.3 0.3
Major Depression (MDD) 0.1 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 -1.0 -0.4 0.6 -1.1
Reaction Time 1.2 2.2 4.9 0.1 1.7 0.4 1.1 -1.2 1.9 0.6 -1.9 1.7 1.4 -0.5 1.7 2.2 2.2 1.6
Verbal and Numeric Reasoning (VNR) 1.6 3.8 7.8 -1.8 1.2 -0.8 0.0 -2.8 1.6 -0.7 -2.7 2.6 2.8 1.4 1.2 2.6 1.9 2.2
Breast Cancer 0.1 0.3 1.3 -0.4 -0.2 -0.7 0.0 0.8 -0.7 -0.1 0.5 0.1 0.7 -0.1 0.3 -0.5 -1.1 -0.5
Ovarian Cancer 0.2 0.2 0.9 0.5 -0.1 0.5 0.3 -0.1 0.8 0.6 -0.1 -0.2 -0.5 -0.3 0.0 0.1 0.9 -0.5
Prostate Cancer 0.2 0.2 0.6 0.3 0.2 0.3 -0.6 -0.5 0.4 0.0 -0.5 0.7 0.7 -0.0 -0.3 0.8 0.4 0.5
Age at First Birth 0.3 0.4 2.1 0.2 -0.3 0.1 -0.8 -0.6 -0.4 -1.4 0.1 0.4 0.4 0.0 -0.5 -0.1 -1.1 0.8
Bipolar Disorder (2011) 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 -0.2 -0.0 0.0
Body Mass Index (BMI) (2010) 0.5 0.7 2.9 -0.7 1.2 -0.4 1.0 -1.0 -0.5 -0.4 -0.8 0.9 0.8 -0.1 1.7 0.6 0.1 -0.0
Coronary Artery Disease (CAD) 0.5 0.6 4.1 1.0 0.0 -0.1 -0.9 0.7 -0.3 -0.9 -0.6 0.5 0.0 -2.0 0.0 0.3 -0.6 0.0
Crohns Disease (2012) 0.8 1.3 4.0 -0.1 0.0 1.0 0.5 1.5 0.4 0.9 1.4 -1.9 -1.4 1.0 -0.6 -1.2 1.1 -2.0
Mean Putamen Volume 0.3 0.3 1.4 1.2 0.5 0.5 -0.1 -0.3 -0.2 -0.4 0.3 -0.2 -0.5 -1.2 -0.0 -0.2 -0.2 -0.9
Fasting Glucose 0.7 0.9 3.0 0.6 -0.1 -0.3 -0.2 1.0 -1.7 -0.8 0.3 0.3 -1.7 -0.9 0.3 -1.1 -1.3 -0.9
HbA1C 1.2 1.3 5.1 2.3 -0.7 1.5 -0.2 1.5 0.2 0.9 0.8 -0.9 -1.6 -1.7 -0.9 -1.0 -0.3 0.4
HDL Cholesterol 0.4 0.7 2.1 0.4 -0.3 -0.0 -0.6 1.0 -0.7 -0.4 1.1 -1.0 -1.4 -0.4 -1.0 -1.1 -0.6 -1.3
LDL Cholesterol 0.6 0.9 3.7 -1.3 -0.1 -0.6 0.4 1.9 -1.2 0.1 1.2 -1.2 -0.8 0.7 -0.3 -1.2 -0.8 -0.5
Lupus 0.6 0.9 3.8 -0.1 -1.3 -1.1 -1.9 0.1 -0.5 -1.2 0.2 -0.5 -0.3 0.2 -1.8 -0.3 -0.2 -0.8
Neuroticism (2016) 0.2 0.3 1.2 -0.2 0.7 -0.2 0.1 -0.3 0.1 -1.1 -0.7 0.8 -0.1 0.1 0.5 0.7 0.3 0.0
Primary Biliary Cirrhosis 0.4 0.6 1.6 -0.7 0.4 1.3 1.0 0.3 0.5 0.4 0.3 -0.6 -0.5 1.2 1.1 -0.1 1.0 -0.9
Rheumatoid Arthritis 1.4 2.0 5.0 -1.6 1.3 0.4 1.2 -1.6 1.3 0.8 -1.4 0.8 1.9 1.4 1.9 1.4 2.2 0.5
Schizophrenia (2014) 0.8 1.7 7.0 -1.3 0.1 0.6 0.8 -1.1 1.4 0.2 -0.5 0.7 2.0 2.7 0.1 0.9 1.2 2.3
Triglycerides 0.1 0.2 0.9 0.1 -0.1 0.9 0.0 0.6 0.5 0.9 0.3 -0.4 0.0 0.1 -0.5 -0.0 -0.0 0.4
Type 2 Diabetes (T2D) (2012) 0.9 1.0 3.1 -0.8 0.0 -0.7 -0.8 1.1 -0.7 -0.7 1.8 -1.7 -0.4 1.3 0.0 -1.7 -0.5 0.0
Ulcerative Colitis 0.3 0.5 2.5 0.6 0.0 0.1 -0.8 1.6 -0.5 -0.0 0.6 -0.4 -0.6 -0.4 0.6 -0.3 -0.3 -1.5
Blood Eosinophil Count 0.2 1.6 5.1 -0.2 2.3 1.0 1.8 -1.1 0.8 0.9 -0.9 1.3 1.2 0.1 2.2 1.3 0.3 1.4
Blood Platelet Count 0.3 3.0 9.6 2.2 1.9 3.1 1.7 -2.3 1.9 -1.7 -1.1 0.4 -0.4 -1.7 1.4 1.1 2.3 -0.4
Blood Red Count 1.9 18.0 45.4 2.0 -1.8 2.4 1.3 6.7 -3.4 2.6 5.6 -6.2 -6.2 -1.7 -1.7 -6.0 -2.5 -6.0
Blood White Count 3.8 28.5 77.5 3.3 -2.5 4.6 2.0 8.5 -2.0 4.1 8.2 -8.8 -6.3 -1.6 -3.3 -6.7 -1.7 -6.9
Heel T-Score 0.1 0.9 3.6 1.6 -0.4 1.6 0.2 -1.0 1.9 0.5 0.3 -0.4 -0.1 -0.3 -0.8 0.5 1.6 0.3
BMI 0.1 0.9 2.5 -0.4 1.1 0.6 1.6 -1.0 0.6 0.2 -0.8 0.4 1.5 0.2 1.6 0.7 1.1 0.0
Height 0.2 4.1 11.4 2.4 0.7 2.8 0.6 1.8 -1.5 1.5 2.7 -2.8 -1.5 -1.8 -0.7 -2.2 -1.4 -3.4
Waist Hip Ratio (WHR) 1.4 6.3 23.9 0.1 1.0 3.2 2.7 3.7 -0.7 4.9 3.1 -3.3 -2.2 -0.0 0.5 -2.7 -0.4 -2.2
Systolic Blood Pressure 0.5 2.3 9.7 -0.0 -0.3 1.7 1.9 3.1 1.3 2.5 0.7 -1.7 -1.2 -0.2 0.4 -0.6 1.8 -1.5
Smoking Status 0.4 1.0 3.1 0.5 1.4 1.1 1.8 -0.7 -0.5 1.1 0.0 -0.1 -0.9 -1.0 1.7 -0.3 0.1 -1.5
Allergy or Eczema 0.7 1.8 6.8 0.7 1.1 1.2 0.3 -1.8 2.5 0.5 -2.0 1.0 0.7 -0.0 0.2 1.6 2.6 0.2
Cardiovascular Disease 0.9 2.8 10.6 -0.9 1.0 -0.0 2.3 3.3 -0.9 2.0 1.7 -1.9 -0.6 -0.2 1.2 -1.7 -0.1 -3.0
Hypothyroidism (self reported) 0.1 0.3 1.0 0.0 0.4 -0.6 0.4 -0.8 0.0 -0.8 -0.1 -0.2 -1.0 -0.4 0.3 0.2 0.9 -0.6
Respiratory disease 0.5 1.1 2.8 -0.2 -0.6 -0.5 -0.7 -1.0 1.0 -0.6 -1.4 1.4 1.2 0.8 -0.1 1.4 1.3 1.7
Type 2 Diabetes (T2D) (2018) 0.8 1.6 7.4 1.2 -0.3 0.1 -0.1 0.8 -1.1 0.6 1.3 -1.1 -2.7 -1.4 -0.4 -1.4 -1.0 -2.0
Lung FEV1/FVC ratio 0.2 1.1 5.3 1.8 -0.3 -0.8 -0.3 -0.2 0.9 -0.6 -1.4 0.8 -0.2 -2.3 0.5 1.2 0.9 -0.9
Lung FVC 0.8 4.1 12.1 -0.1 -1.2 -1.1 -1.4 1.9 -3.5 -1.3 2.6 -1.8 -2.2 -0.7 -1.4 -2.9 -3.3 -1.7
Neuroticism 1.0 2.3 4.6 1.2 2.2 1.6 1.9 -1.2 1.7 1.1 -1.5 1.2 0.6 -1.1 2.1 1.8 1.9 0.4
Chronotype (morning person) 0.1 0.3 0.9 0.4 -0.6 1.0 -0.4 -0.3 0.7 -0.7 -0.3 0.3 -0.8 0.1 -0.5 0.3 1.0 0.2
Hair Pigment 0.0 0.9 3.4 -0.1 -1.8 0.0 -1.4 0.1 0.3 -0.4 0.4 -0.4 0.8 1.0 -1.8 -0.1 -0.2 1.4
Tanning 0.2 2.6 6.5 0.3 0.7 1.0 0.2 1.5 -2.4 1.4 2.2 -1.6 -2.6 -0.7 -0.1 -2.4 -2.2 -1.7
Hand grip strength (left) 0.8 2.2 4.7 -0.3 -2.2 -0.7 -1.5 1.6 -1.7 -1.4 1.7 -1.3 -1.1 0.3 -1.8 -1.9 -1.9 -1.0
Number of treatments/medications taken 1.3 2.3 6.9 -1.4 0.7 1.1 2.5 2.6 0.0 2.6 1.7 -1.8 -0.2 1.3 0.9 -1.0 0.6 -0.8
Average weekly spirits intake 0.6 0.8 1.9 -0.8 -0.7 -0.0 -0.0 1.4 -0.7 -0.8 1.1 -1.4 -0.7 0.9 -0.8 -1.4 -0.4 -0.6
Sensitivity / hurt feelings 0.9 1.6 4.8 0.2 0.5 0.4 0.3 -1.7 1.6 -0.1 -2.2 1.7 1.2 0.0 0.9 1.9 1.5 1.4
Frequency of depressed mood in last 2 weeks 0.2 0.3 1.0 0.2 1.0 0.3 0.9 -0.2 0.6 0.6 -0.1 -0.3 -0.1 -0.2 0.5 0.2 0.9 -0.3
Hearing difficulty/problems: Yes 0.3 0.5 1.6 0.3 0.2 0.5 0.8 -0.9 0.4 0.5 -0.8 1.3 0.2 0.0 1.1 0.7 0.2 1.0
Relative age of first facial hair 0.4 0.8 3.7 1.9 -0.8 1.0 -0.6 0.1 1.2 0.3 0.1 -0.5 -0.4 -0.8 -1.2 0.3 1.0 -1.0
Other serious medical condition/disability diagnosed by doctor 1.2 1.5 6.5 -2.5 0.6 0.3 1.5 0.3 0.1 0.5 -0.4 0.5 1.6 2.3 1.4 0.3 0.0 1.9
Ever used hormone-replacement therapy (HRT) 0.8 1.0 3.8 -0.8 1.6 0.6 2.0 -0.4 -0.1 0.7 0.2 0.2 1.6 0.4 1.7 0.1 -0.7 0.7
Ever had hysterectomy (womb removed) 0.1 0.2 1.0 -0.0 0.2 -0.1 -0.1 -0.2 -0.4 0.4 -0.1 -0.1 -0.7 -0.5 0.2 -0.3 -0.0 -1.0
Systolic blood pressure, automated reading 0.8 2.4 6.7 0.3 0.8 1.2 2.6 2.6 -0.3 2.1 1.4 -1.8 -1.2 -1.3 1.4 -1.2 0.1 -2.2
Eye problems/disorders: Diabetes related eye disease 1.0 1.1 4.1 -0.4 -1.3 -1.5 -1.8 -0.0 0.1 -2.0 -0.4 0.7 0.2 0.9 -1.5 0.1 -0.4 0.9
Angina 0.2 0.3 0.9 0.8 -0.2 0.0 0.4 0.7 0.1 0.5 0.6 -0.4 -0.5 -0.8 0.1 -0.2 -0.2 -1.0
Medication for hormone replacement therapy 0.8 0.9 3.2 -1.6 -0.6 -0.2 0.3 0.7 -0.2 0.8 0.5 -0.5 1.5 1.8 -0.4 -0.6 -0.7 1.5
Vitamin and mineral supplements 1.7 2.3 6.4 1.0 -1.0 0.9 0.0 2.2 -1.3 0.8 1.4 -1.8 -2.5 -1.0 -0.7 -2.1 -1.2 -2.3
Supplements: Zinc 3.0 3.3 7.8 1.1 2.8 1.1 1.8 -1.8 1.7 1.4 -1.8 1.7 1.4 -1.5 2.6 2.4 2.0 0.8
Medication: Co-codamol 0.9 1.0 2.3 -0.6 0.1 0.6 0.6 -1.1 1.4 0.3 -0.6 0.5 1.5 1.4 0.2 1.1 1.4 1.5
Medication: Metformin 1.3 1.8 5.1 -0.2 -0.1 0.2 0.3 2.0 -1.4 1.1 1.5 -1.5 -2.3 -0.4 -0.4 -2.0 -1.3 -2.1
Diabetes (father) 0.5 0.6 1.9 0.3 -1.4 0.8 -0.5 0.6 1.2 0.0 0.1 -0.5 -0.3 0.8 -1.3 0.2 1.1 0.0
Diabetes (mother) 0.9 1.2 3.6 -0.1 -0.1 0.6 0.3 1.0 -0.5 0.6 1.3 -1.9 -1.6 0.5 -0.9 -1.7 -0.1 -1.9
Severe depression (siblings) 0.6 0.6 1.7 -1.2 1.3 -0.3 0.5 -1.2 -0.4 -0.6 -0.5 0.9 0.3 0.9 1.1 0.0 -0.6 0.8
Pack years adult smoking proportion 1.1 1.7 7.8 1.4 0.8 2.8 1.7 -0.1 1.3 2.3 0.2 -0.1 0.9 -0.7 1.0 0.9 1.3 0.2
Impedance of leg (right) 0.6 2.8 5.9 1.6 0.0 0.9 -0.2 2.0 -1.2 1.5 2.3 -2.4 -2.4 -1.8 -1.0 -2.0 -1.3 -2.0
Leg fat-free mass (left) 0.1 0.4 2.3 -1.2 -0.1 0.4 0.6 -0.3 0.2 -0.2 -0.4 0.1 0.9 1.5 0.2 0.2 0.8 0.1
Trunk fat percentage 0.5 1.9 7.2 -0.2 2.3 1.4 2.7 0.4 0.7 1.7 -0.7 0.1 1.2 -0.5 2.5 0.6 1.0 -0.8
Hand grip strength (right) 0.6 1.7 4.3 -0.2 -1.8 -1.4 -2.1 0.8 -1.4 -2.1 0.9 -0.2 0.0 0.1 -1.6 -0.9 -2.0 -0.1
Townsend deprivation index at recruitment 1.3 1.8 5.2 -0.6 1.2 -0.4 0.5 -1.9 0.2 0.4 -1.7 2.3 1.5 0.1 1.8 1.8 0.6 1.9
Current tobacco smoking 0.2 0.4 1.2 0.7 0.0 0.7 0.4 0.5 -0.1 0.6 0.5 -0.8 -1.0 -0.6 -0.0 -0.5 0.0 -1.1
Average weekly fortified wine intake 0.8 0.9 2.7 -0.2 -0.2 -1.1 -0.7 -0.4 0.4 -1.3 -1.6 1.6 0.7 -0.4 0.5 1.2 0.8 1.2
Maternal smoking around birth 0.1 0.2 0.5 0.0 -0.2 0.4 0.6 0.7 0.6 0.7 -0.1 -0.0 0.2 -0.1 0.3 0.3 0.7 0.2
Fed-up feelings 0.2 0.3 0.9 -0.5 0.4 0.7 1.0 0.2 0.4 0.6 0.2 -0.2 -0.4 0.9 0.3 -0.2 0.7 0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 0.8 0.8 -0.1 0.5 0.2 0.6 0.1 0.7 0.5 -0.7 -0.4 -0.5 -0.3 -0.3 0.1 -0.9
Relative age voice broke 0.8 1.2 3.8 1.4 0.3 1.2 0.5 1.0 0.0 1.7 0.9 -1.6 -1.0 -1.2 -0.3 -0.7 0.1 -2.0
Taking other prescription medications 1.1 1.7 5.7 -1.0 0.8 0.6 1.7 2.4 -1.0 1.2 1.7 -1.6 -1.0 0.6 0.7 -1.6 -0.7 -1.5
Age when periods started (menarche) 0.6 1.4 4.3 -1.1 -1.8 -0.1 -0.9 1.4 0.6 -1.0 0.8 -1.5 0.3 2.0 -2.1 -0.7 0.7 -0.3
Bilateral oophorectomy (both ovaries removed) 2.5 2.9 9.2 0.2 1.0 -1.5 0.4 -1.9 0.4 -0.6 -2.7 3.0 2.1 -1.4 2.6 2.5 0.2 0.9
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.5 1.3 1.1 -0.8 -0.1 -0.8 -0.9 0.6 -1.1 -0.2 0.0 0.1 -0.5 -1.0 0.3 0.4 0.9
Tinnitus: Yes, but not now, but have in the past 0.5 0.6 1.3 0.2 0.5 0.7 0.6 -1.1 0.9 1.1 -0.9 0.8 0.8 0.0 0.9 0.7 0.6 0.4
Qualifications: CSEs or equivalent 1.0 1.4 3.7 1.3 -1.7 -0.7 -1.9 0.7 -0.9 -0.6 0.9 -0.7 -1.1 -1.3 -1.6 -0.8 -1.2 -0.9
Serious illness, injury or assault to yourself 1.8 2.1 6.5 -2.4 -1.5 -2.6 -1.7 -0.6 -0.4 -1.1 -1.3 1.4 0.7 2.3 -0.7 0.4 -0.6 1.5
High blood pressure 0.6 1.7 6.2 0.6 0.6 0.8 1.7 2.1 0.4 1.5 1.5 -1.9 -0.9 -0.5 0.3 -0.9 1.0 -2.5
Hayfever, allergic rhinitis or eczema 0.4 1.0 3.7 0.1 0.2 0.4 -0.1 -1.4 1.8 0.2 -1.6 0.8 0.5 0.7 -0.2 1.2 1.9 0.5
Multivitamins +/- minerals 3.1 4.0 10.8 -1.2 1.5 -0.1 0.4 -2.9 2.1 -0.5 -1.8 2.3 3.3 1.6 0.9 2.7 1.7 3.1
Stomach or abdominal pain in last month 0.6 0.7 2.0 -0.3 -1.0 -1.1 -1.2 -0.6 -0.6 -1.4 0.2 0.1 -0.7 0.6 -1.2 -0.5 -1.1 0.3
Supplements: Glucosamine 1.1 1.5 6.0 -1.4 1.7 0.3 2.4 1.1 -1.3 0.5 0.8 -0.3 0.5 0.4 2.3 -0.7 -1.0 -0.1
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 3.6 -0.1 0.5 1.4 1.5 -0.7 1.1 1.9 -0.3 -0.3 0.5 0.6 0.7 0.3 1.2 0.2
Medication: Atenolol 1.6 2.0 4.7 -0.7 -1.8 -0.0 -0.6 2.2 -1.0 0.3 2.1 -1.8 -1.8 1.2 -1.7 -1.8 -0.4 -1.5
Medication: Levothyroxine sodium 0.4 0.7 2.4 -0.9 -1.4 -1.5 -0.8 0.2 0.1 -1.6 -0.8 0.3 -0.4 0.8 -0.6 0.2 0.9 -0.2
Sitting height 0.5 3.5 7.8 -0.4 -1.3 -0.1 -1.0 2.8 -2.2 0.1 2.6 -2.7 -1.8 0.4 -2.0 -2.6 -1.6 -2.3
Chronic bronchitis/emphysema (father) 0.1 0.2 0.7 0.8 0.4 0.4 0.2 -0.4 0.3 0.3 -0.0 0.4 0.4 -0.5 0.4 0.4 0.0 -0.0
High blood pressure (mother) 1.1 1.5 4.6 0.4 0.8 1.8 2.2 1.4 0.5 1.4 1.3 -1.5 -1.0 -0.4 0.7 -0.8 1.0 -1.4
Body mass index (BMI) 0.2 0.7 2.0 -0.8 0.3 0.6 1.2 -0.2 0.6 0.0 -1.0 0.8 1.4 0.7 1.2 0.7 0.9 0.6
Impedance of leg (left) 0.5 2.3 4.5 1.6 0.6 1.2 0.4 1.7 -0.7 1.9 1.9 -2.1 -2.1 -1.9 -0.4 -1.5 -0.9 -1.9
Leg predicted mass (left) 0.1 0.4 2.2 -1.2 0.0 0.4 0.7 -0.3 0.2 -0.1 -0.4 0.2 0.9 1.5 0.3 0.2 0.8 0.1
Trunk fat mass 0.3 1.3 5.7 -0.3 1.6 1.6 2.4 0.9 0.3 1.5 -0.1 -0.5 0.8 -0.2 1.8 -0.1 0.7 -1.1
Waist circumference 0.3 1.1 3.9 -0.6 0.5 1.8 2.0 1.3 0.1 1.7 0.5 -0.9 0.2 0.7 1.0 -0.6 0.4 -0.6
Number of incorrect matches in round 0.8 1.4 4.6 1.0 -0.5 0.4 -0.5 1.4 -1.2 -0.7 1.1 -1.2 -2.1 -1.1 -0.8 -1.4 -0.8 -2.0
Past tobacco smoking 0.1 0.2 0.7 -0.4 -0.2 -0.7 -0.8 0.3 0.1 -0.4 -0.2 0.1 0.1 0.3 -0.7 0.4 0.5 0.5
Alcohol usually taken with meals 0.4 0.6 3.0 -0.4 -1.0 -1.2 -0.7 0.7 0.3 -1.7 0.3 -0.1 0.6 0.6 -1.0 0.1 -0.1 0.7
Nervous feelings 1.8 3.3 9.2 2.2 3.0 2.3 2.6 0.5 0.5 1.6 0.4 -0.7 -1.5 -2.7 2.1 0.3 1.4 -2.1
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 4.8 2.2 -0.5 0.6 -1.0 -0.6 1.1 -0.5 0.1 -0.3 -0.2 -1.4 -1.1 0.5 0.6 -0.6
Hearing difficulty/problems with background noise 2.4 3.8 11.5 -0.2 1.3 -1.3 0.5 -3.4 1.4 -0.8 -3.0 3.4 1.5 -0.4 2.3 2.7 1.4 1.6
Hair/balding pattern: Pattern 2 2.6 3.3 7.8 -1.0 -2.0 -1.3 -1.4 1.8 -2.7 0.0 2.5 -2.0 -1.1 0.7 -2.0 -2.6 -2.8 -0.5
Had menopause 0.8 1.1 3.1 0.7 0.5 1.6 1.1 0.8 0.1 0.8 1.2 -1.6 -1.0 -0.2 -0.1 -1.1 0.5 -1.8
Had other major operations 0.2 0.2 0.8 0.3 -0.1 0.4 0.9 0.9 -0.0 0.0 0.1 -0.2 -0.3 -0.5 0.6 -0.3 0.2 -0.5
Forced vital capacity (FVC) 0.4 1.7 3.7 -0.1 -1.1 -1.1 -1.5 0.5 -1.9 -1.1 1.7 -1.2 -1.3 -0.1 -1.6 -1.6 -1.5 -1.5
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 2.1 1.5 -0.7 0.9 -0.3 -0.7 0.5 -0.2 0.4 -0.6 -0.5 -0.4 -1.1 -0.1 0.5 0.2
Ever unenthusiastic/disinterested for a whole week 0.3 0.3 1.5 -0.1 0.3 0.8 1.2 -0.1 0.5 0.9 0.2 0.1 -0.2 0.3 0.8 0.1 0.7 0.3
Qualifications: None of the above 0.2 0.5 1.7 0.3 0.3 0.8 1.3 0.1 1.0 0.5 0.0 0.2 0.8 0.3 0.8 0.9 1.0 0.2
Financial difficulties in last 2 years 0.9 1.3 3.2 0.0 0.9 -0.9 -0.1 -1.7 0.6 -0.5 -1.8 1.5 1.5 -0.2 0.8 1.8 1.1 0.7
Mouth/teeth dental problems 0.1 0.2 0.6 -0.7 -0.2 -0.7 -0.1 0.7 -0.5 -0.1 -0.1 0.2 -0.5 -0.2 0.4 -0.0 -0.3 0.0
Heart attack 1.7 2.2 5.3 1.1 1.5 1.4 1.7 0.9 -1.3 1.7 1.4 -1.0 -1.5 -2.1 1.5 -1.0 -0.5 -2.3
Allergy 0.4 1.0 4.6 -0.7 0.2 -1.1 -0.2 0.7 -1.9 -0.7 1.3 -0.3 -0.1 -0.3 0.2 -1.0 -2.1 -0.8
Pain all over the body in last month 0.3 0.4 1.4 0.1 0.0 1.1 -0.0 -0.7 1.2 0.2 -0.3 -0.0 0.9 0.6 -0.3 0.5 0.2 0.8
Diabetes (self-reported) 1.3 2.0 7.4 0.8 -1.2 -0.3 -1.2 1.1 -1.1 -0.4 1.6 -1.5 -2.7 -0.4 -1.8 -1.9 -1.1 -1.8
Hayfever/allergic rhinitis (self-reported) 1.4 1.9 3.4 0.2 -1.4 -1.0 -1.8 -1.6 1.4 -0.9 -1.6 1.7 1.4 1.0 -1.1 1.7 0.8 1.8
Medication: Ramipril 0.9 1.2 4.0 -1.5 0.2 -0.4 0.7 1.5 -2.0 0.4 1.2 -0.6 -0.8 0.8 0.4 -1.6 -1.5 -0.4
Medication: Simvastatin 0.9 1.3 4.2 -1.3 -0.6 -0.2 0.6 2.0 -1.1 0.4 1.3 -1.8 -1.0 0.8 -0.4 -1.6 -0.3 -1.6
Fluid intelligence score 1.7 3.6 7.1 -2.1 2.7 0.5 1.9 -2.3 1.5 0.3 -2.1 1.9 2.1 1.4 2.4 1.9 2.1 1.5
Illnesses of siblings 0.4 0.5 1.9 0.5 -0.2 -0.5 -0.8 -0.5 0.2 -1.0 -0.6 0.9 1.1 -0.5 -0.1 0.8 -0.7 1.4
Neuroticism score 0.6 1.4 3.8 0.9 1.3 1.3 1.3 -1.2 1.8 0.6 -1.0 0.8 0.0 -0.4 1.1 1.5 2.0 0.5
Weight 0.1 0.4 1.8 -0.2 0.3 1.3 1.2 0.6 0.2 0.6 0.0 -0.5 0.5 0.5 0.6 -0.2 0.7 -0.8
Impedance of arm (right) 0.2 1.0 7.3 -0.1 2.7 0.1 1.1 -0.3 0.4 1.6 -0.4 0.1 0.3 -0.8 1.4 0.5 0.2 -0.3
Arm fat percentage (right) 0.4 1.6 5.8 -1.0 1.9 0.9 2.4 0.3 0.7 1.4 -1.0 0.5 1.6 0.2 2.4 0.7 1.0 0.0
Trunk fat-free mass 0.2 1.4 2.9 -0.1 -1.7 1.0 -0.5 1.4 -1.0 -0.4 1.7 -1.6 -0.8 1.0 -1.6 -1.7 -0.7 -1.0
Hip circumference 0.1 0.5 1.7 -0.9 0.3 0.4 0.4 -0.8 0.5 -0.7 -0.7 0.3 1.3 1.2 0.2 0.5 0.8 0.2
Time employed in main current job 0.2 0.2 0.9 1.0 0.0 -0.1 -0.7 -0.3 0.0 -0.5 -0.3 0.3 -0.2 -0.7 -0.4 0.4 -0.0 0.3
Alcohol intake versus 10 years previously 1.6 2.4 6.4 1.6 2.5 2.5 2.3 -0.6 1.5 1.7 -0.3 0.1 0.5 -1.8 1.9 1.0 1.3 0.0
Father’s age at death 0.8 1.0 3.8 0.9 -0.6 -0.2 -1.4 -0.0 -0.9 -1.3 1.0 -0.8 -2.0 -0.3 -1.7 -0.9 -0.8 -0.2
Worrier / anxious feelings 1.5 2.8 8.1 1.2 2.9 1.3 2.2 -1.2 1.4 1.2 -1.6 1.2 -0.1 -1.8 2.7 1.8 1.7 -0.2
Frequency of tiredness / lethargy in last 2 weeks 0.9 1.5 6.0 1.4 -1.5 0.4 -1.5 0.6 0.5 0.0 1.3 -1.6 -1.3 -0.1 -2.5 -0.8 0.3 -1.6
Falls in the last year 0.6 0.9 2.6 0.5 1.2 0.9 1.4 -0.7 0.3 1.6 -0.4 0.6 0.0 -0.6 1.5 0.8 1.1 -0.1
Hair/balding pattern: Pattern 3 1.6 2.3 11.0 2.3 -0.1 2.2 -0.0 -0.4 3.3 0.7 -0.7 -0.2 0.7 -0.5 -0.9 1.5 3.0 0.3
Number of live births 1.7 2.5 8.2 0.1 1.4 1.6 2.9 1.3 -1.3 2.4 1.3 -1.6 -0.8 -0.7 1.9 -1.6 -0.4 -1.9
Forced expiratory volume in 1-second (FEV1) 0.5 1.7 4.1 -0.4 -1.7 -1.7 -2.0 0.4 -1.5 -1.6 1.1 -0.8 -1.0 0.1 -2.0 -1.2 -1.1 -1.2
Pulse rate 1.5 2.6 8.9 1.3 -2.6 0.3 -2.0 2.0 -0.6 -0.3 1.9 -2.1 -1.0 -0.2 -3.0 -1.5 -0.7 -1.2
Happiness 0.1 0.2 0.9 -0.8 -0.4 0.2 0.0 -0.2 0.4 0.1 -0.2 -0.2 0.8 0.9 -0.2 -0.0 0.2 0.1
Noisy workplace 0.4 0.5 1.2 -0.6 0.7 0.4 0.9 -1.1 0.5 0.5 -0.6 0.7 0.3 0.8 1.0 0.5 0.3 0.8
Qualifications: A levels/AS levels or equivalent 0.9 2.0 8.6 -2.5 -1.0 -1.1 -1.5 -0.5 -1.2 -0.5 0.8 -0.7 0.3 2.9 -1.9 -1.1 -1.1 1.4
Serious illness, injury or assault of a close relative in last 2 years 0.9 1.0 3.9 -0.9 -0.8 -0.9 -0.9 2.0 -1.3 -0.2 1.3 -1.0 -0.5 0.6 -1.1 -1.0 -1.0 -0.0
Mouth/teeth dental problems: Dentures 0.4 0.6 1.6 1.2 0.3 0.7 0.8 0.9 -0.4 0.3 1.2 -1.1 0.2 -1.1 0.2 -0.6 -0.4 -1.0
Asthma 0.4 0.8 2.2 0.6 -0.4 -0.2 -0.5 -0.9 1.1 -0.3 -1.3 1.2 0.5 -0.1 -0.1 1.4 1.3 1.5
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.8 2.6 -0.2 -1.5 -0.3 -0.7 1.6 0.8 0.1 0.6 -0.8 -0.9 1.1 -1.5 -0.5 0.4 -0.0
Medication: Cholesterol lowering 2.7 4.2 18.5 -0.9 -2.2 -0.3 -0.0 4.3 -1.5 -0.0 2.7 -2.9 -1.9 0.8 -1.5 -2.8 -1.4 -2.0
Depression (self-reported) 0.4 0.4 1.4 1.1 -0.9 0.5 -0.5 0.3 0.3 0.7 0.3 -0.2 -1.2 -0.7 -0.7 -0.2 -0.0 -0.7
Medication: Lansoprazole 0.7 0.8 4.7 -0.5 0.7 1.4 2.2 0.8 1.0 0.8 -0.0 -0.3 0.1 0.7 1.2 0.1 0.8 0.6
Prospective memory result 0.3 0.3 0.9 0.9 -0.2 0.4 0.4 0.8 -0.3 0.6 0.3 -0.5 -0.9 -0.8 0.1 -0.1 -0.1 -0.7
Lung cancer (father) 1.0 1.2 3.4 -1.6 1.1 -0.9 1.0 -0.8 0.3 -0.2 -1.1 1.2 1.8 1.0 1.5 0.8 0.3 1.4
Illnesses of mother 0.6 0.7 2.3 0.8 -0.1 -0.8 -1.1 0.0 -1.2 -1.3 0.0 -0.1 -0.6 -1.5 -0.3 -0.3 -1.4 -0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 1.8 3.2 0.6 -1.6 -1.4 -1.8 1.3 -1.4 -1.4 1.4 -1.1 -1.4 -1.1 -1.7 -1.1 -0.9 -1.6
Pulse wave Arterial Stiffness index 0.1 0.1 0.7 0.3 0.0 -0.3 -0.0 -0.2 0.4 -0.1 -0.2 -0.0 0.8 -0.2 -0.1 0.2 -0.1 0.3
Impedance of arm (left) 0.3 1.2 8.3 0.1 2.9 -0.1 1.0 -0.8 0.4 1.4 -0.8 0.6 0.7 -1.2 1.6 0.9 0.1 0.0
Arm fat mass (right) 0.2 1.0 4.1 -1.0 1.2 1.0 2.0 0.4 0.3 0.9 -0.6 0.2 1.2 0.5 1.8 0.3 0.7 -0.2
Trunk predicted mass 0.2 1.4 2.9 -0.1 -1.7 0.9 -0.5 1.4 -1.1 -0.5 1.7 -1.6 -0.8 1.0 -1.6 -1.7 -0.7 -0.9
Standing height 0.2 2.2 7.1 1.0 -0.2 1.6 -0.2 1.5 -0.7 1.0 2.0 -2.5 -1.6 -0.3 -1.5 -1.8 -0.4 -2.7
Length of working week for main job 0.2 0.2 0.9 -0.3 1.0 0.7 0.4 -0.7 -0.3 0.9 0.0 0.0 0.2 0.3 0.4 0.0 -0.2 0.1
Exposure to tobacco smoke at home 1.4 1.5 5.0 -1.0 -0.2 -1.3 -0.8 -1.8 0.1 -1.0 -1.2 2.1 1.0 0.7 0.2 1.7 0.4 2.2
Breastfed as a baby 0.3 0.3 1.3 -0.6 0.0 0.3 -0.3 0.1 -1.1 -0.1 1.0 -0.5 -0.3 0.5 -0.3 -0.8 -0.8 -0.4
Tense / ‘highly strung’ 2.1 3.5 7.8 2.4 2.7 2.6 2.8 -0.6 0.8 2.0 0.3 -0.5 -1.5 -2.4 2.1 0.4 1.5 -2.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 1.7 -0.8 0.4 -0.4 -0.6 -1.3 -0.1 -0.2 -0.5 0.7 0.4 1.0 -0.4 0.4 0.2 1.1
Hair/balding pattern: Pattern 4 0.5 1.2 3.7 -0.2 0.1 -0.9 -0.2 -1.0 0.7 -1.9 -1.9 1.9 0.9 -0.1 0.9 1.4 0.4 1.1
Birth weight of first child 0.8 1.5 5.5 -0.4 0.3 0.0 -0.1 -0.8 2.3 -0.4 -1.3 0.8 2.0 1.3 -0.3 1.7 1.6 1.7
Peak expiratory flow (PEF) 0.6 1.3 5.4 0.4 -2.2 -0.8 -2.3 -0.3 0.1 -1.6 0.4 -0.4 0.1 0.3 -2.3 -0.1 -0.1 -0.3
Pulse wave reflection index 0.4 0.5 2.2 -0.5 1.5 0.7 1.2 -0.9 0.5 0.6 -0.2 -0.2 0.0 0.8 0.6 -0.2 0.5 -0.2
Ever highly irritable/argumentative for 2 days 1.2 1.4 4.9 -0.1 -0.0 1.7 0.7 -1.2 2.2 0.6 -0.4 0.0 1.3 1.8 -0.4 0.8 1.3 1.9
Loud music exposure frequency 0.4 0.4 1.2 -0.6 -0.6 -0.6 0.1 -0.2 1.0 0.0 -0.9 0.7 0.4 0.4 0.3 1.0 1.1 0.6
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 1.4 -0.6 -0.1 0.4 -1.0 -0.3 -0.0 -0.1 0.1 -0.5 -0.3 0.9 -1.2 -0.6 -0.3 0.1
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 2.6 0.4 0.8 1.6 1.1 0.1 0.3 0.9 0.1 0.3 0.5 0.1 0.6 0.1 -0.0 0.6
Blood clot in the leg (DVT) 0.2 0.2 1.2 -1.1 0.2 0.0 0.6 0.4 -0.4 -0.2 -0.4 0.3 -0.1 0.3 1.0 -0.0 0.3 -0.3
Medication: Paracetamol 2.3 3.8 12.3 -0.4 1.7 1.9 2.5 0.1 3.4 1.7 -2.0 0.9 1.7 0.9 1.9 2.0 3.5 1.1
Headache pain in last month 0.1 0.2 0.8 0.7 -0.6 -0.1 0.1 0.6 0.9 -0.3 -0.2 -0.1 0.3 -0.3 -0.0 0.5 0.5 -0.5
Medication for cholesterol, blood pressure or diabetes 1.7 2.8 16.9 0.7 1.3 -0.6 -1.0 -4.1 0.4 -1.2 -2.3 2.6 0.9 -0.8 0.7 2.0 0.6 1.2
Glaucoma (self-reported) 0.6 0.7 1.9 1.2 1.2 1.4 1.0 -0.5 0.3 0.2 -0.1 -0.1 -0.4 -1.4 1.1 0.1 0.6 -1.0
Gout (self-reported) 0.6 0.8 2.7 -0.8 -0.6 -0.7 0.1 0.7 -1.6 -0.3 1.0 -0.8 -0.3 0.7 -0.3 -1.4 -1.6 -0.2
Hypothyroidism/myxoedema (self-reported) 0.2 0.4 1.5 -0.1 -0.8 -0.9 -0.3 0.8 -0.3 -1.2 0.3 -0.4 -0.9 -0.1 -0.4 -0.4 0.4 -0.9
Medication: Amlodipine 0.6 0.8 2.3 0.1 1.4 0.2 1.4 -0.3 0.5 1.2 -0.3 0.3 -0.3 -0.7 1.3 0.7 1.5 -0.9
Medication: Ventolin 100micrograms inhaler 0.2 0.2 0.7 -0.7 0.5 -0.8 0.4 0.2 -0.5 0.4 -0.2 0.3 -0.0 0.4 0.7 0.1 -0.4 0.5
Birth weight 1.5 3.2 8.2 -0.4 0.3 -1.1 -0.7 -2.4 2.3 -1.0 -2.5 2.4 2.7 0.5 0.3 2.9 2.0 1.8
Chronic bronchitis/emphysema (mother) 0.6 0.7 2.1 0.4 0.6 -0.6 0.2 -1.3 0.7 -0.6 -1.0 0.9 1.2 -0.7 0.9 1.4 0.9 0.3
High blood pressure (siblings) 1.0 1.4 5.8 0.8 0.7 1.4 1.7 0.6 0.4 1.6 0.7 -1.1 -1.3 -0.7 0.7 -0.5 1.3 -2.4
Forced vital capacity (FVC), Best measure 0.5 1.8 3.6 0.5 -1.2 -0.7 -1.3 1.5 -1.5 -0.9 1.9 -1.5 -1.4 -0.8 -1.6 -1.5 -1.1 -1.7
Body fat percentage 0.4 1.5 6.6 -0.4 1.9 1.4 2.6 0.7 0.4 1.6 -0.4 -0.2 0.9 -0.3 2.2 0.1 0.8 -0.7
Leg fat percentage (right) 0.3 1.1 3.0 0.1 0.6 1.3 1.7 1.7 -0.7 1.3 1.0 -1.3 -0.3 -0.6 1.1 -1.1 -0.2 -1.2
Arm fat-free mass (right) 0.2 0.9 2.0 -0.1 -1.4 0.9 -0.0 1.2 -0.6 -0.6 1.2 -1.4 -0.5 0.8 -1.1 -1.2 -0.1 -1.2
Exposure to tobacco smoke outside home 0.9 1.2 4.0 -0.9 -1.2 -1.3 -1.3 -0.5 -0.4 -1.9 -0.3 1.3 0.8 0.9 -0.6 0.9 -0.5 2.0
Comparative body size at age 10 0.5 1.3 3.5 -1.2 -1.9 -0.8 -0.8 0.3 -1.1 -1.4 1.1 -0.3 -0.8 1.5 -1.2 -1.0 -1.4 1.0
Number of full brothers 0.9 1.1 3.6 1.7 -0.1 1.8 -0.1 -0.6 1.5 1.9 -0.3 -0.1 -0.1 -1.0 -0.4 0.7 1.5 -0.6
Worry too long after embarrassment 1.0 1.6 4.0 0.8 2.0 1.5 1.8 -0.6 1.1 1.2 -1.0 0.7 0.5 -1.1 1.9 1.2 1.5 -0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.4 -0.2 -0.9 0.3 -0.5 -0.1 0.4 -0.0 0.2 -0.2 -0.8 1.1 -1.2 -0.1 0.2 0.8
Wheeze or whistling in the chest in last year 1.3 2.3 6.8 0.5 1.9 1.8 2.6 0.1 1.4 2.6 -1.1 0.6 -0.0 -0.7 2.4 1.1 1.7 0.2
Number of children fathered 1.7 1.9 5.7 1.2 1.7 2.2 1.8 0.2 2.4 1.4 -0.7 -0.2 -0.1 -0.5 0.8 0.8 2.4 -0.6
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.2 4.3 -1.5 -0.9 -2.1 -1.2 -0.4 0.1 -1.8 -1.1 1.4 0.4 1.0 -0.3 0.9 0.2 0.5
Age at first live birth 0.5 0.8 2.7 -0.4 -0.8 0.5 -0.2 0.6 -0.1 -0.5 1.1 -0.7 1.2 1.3 -1.1 -0.5 -1.1 1.6
Pulse wave peak to peak time 0.1 0.1 0.9 -0.2 0.0 0.4 0.1 0.3 -0.4 0.1 0.4 -0.1 -0.9 0.1 0.1 -0.4 0.0 -0.4
Health satisfaction 0.8 1.1 5.2 -0.7 -2.3 -0.5 -1.1 1.0 0.5 -0.3 0.8 -0.9 0.2 1.7 -1.8 -0.4 -0.1 0.0
Shortness of breath walking on level ground 0.9 1.1 2.6 -1.4 0.6 -1.2 0.7 -1.5 -0.2 0.0 -0.9 1.5 1.0 0.7 1.6 1.1 0.3 1.1
Qualifications: College or University degree 0.2 0.6 2.0 -1.3 0.3 -0.7 0.3 -1.2 -0.4 0.0 -0.2 0.5 0.7 1.1 0.5 0.1 -0.6 1.4
Eye problems/disorders: None of the above 1.3 1.5 2.4 1.6 -0.6 1.1 -1.0 1.4 -1.1 0.6 1.4 -1.5 -1.3 -1.3 -1.3 -1.3 -1.3 -1.3
Mouth/teeth dental problems: Loose teeth 1.3 1.6 4.8 1.9 1.7 1.3 1.4 -0.3 1.0 1.5 -0.6 0.2 -0.0 -2.2 1.4 1.0 1.5 -0.5
Emphysema/chronic bronchitis 0.5 0.5 1.8 0.2 -0.2 -0.2 -0.3 -1.3 1.0 -0.4 -0.6 0.3 0.7 0.5 -0.5 0.9 1.3 1.0
Medication for pain relief, constipation, heartburn 0.7 1.2 4.3 -0.1 -0.4 -1.1 -1.7 -2.1 -1.2 -1.7 -0.5 1.0 0.5 -0.1 -0.6 0.1 -1.5 1.1
Neck or shoulder pain in last month 0.3 0.4 2.1 -0.4 -0.8 -0.5 -0.2 -0.0 0.4 -0.4 -0.4 0.6 1.2 0.8 -0.1 0.8 0.1 1.4
Medication: Blood pressure 0.6 1.1 7.3 0.1 -0.7 0.4 1.0 2.7 0.0 1.0 1.3 -1.5 -0.6 -0.3 -0.0 -0.9 0.2 -1.3
Angina (self-reported) 0.1 0.2 0.7 0.7 -0.1 0.1 0.4 0.6 0.2 0.4 0.4 -0.4 -0.3 -0.7 0.2 -0.1 -0.0 -0.8
Migraine (self-reported) 0.6 0.7 2.0 -0.4 -1.1 0.9 0.1 1.0 -0.2 0.7 1.4 -1.1 -0.5 1.3 -0.8 -0.9 -0.4 -0.1
Medication: Ibuprofen 0.9 1.1 3.8 0.2 -1.4 0.2 -0.6 2.0 0.4 0.2 1.3 -1.5 -1.1 0.7 -1.8 -0.9 -0.0 -0.3
Medication: Allopurinol 0.6 0.8 3.1 -0.0 0.2 -0.0 0.3 0.8 -1.7 0.3 1.2 -1.1 -0.8 -0.1 -0.2 -1.4 -1.4 -0.9
Medication: Omeprazole 0.3 0.3 2.1 0.8 0.3 0.4 -0.1 0.5 0.8 0.1 0.1 -0.7 -0.2 -0.7 -0.5 -0.2 0.4 -1.5
Medication: Seretide 50 evohaler 1.5 1.7 3.8 -0.7 1.1 -0.4 1.0 -1.5 1.7 -0.6 -1.5 1.2 1.7 0.9 1.2 2.0 1.9 1.4
Mean time to correctly identify matches 0.4 0.9 1.9 0.1 1.4 0.8 1.2 -0.4 1.0 0.5 -0.7 0.8 0.8 -0.3 1.3 1.0 1.2 1.2
Heart disease (mother) 0.2 0.2 1.2 0.2 -0.3 -0.2 -0.7 -1.1 0.5 0.8 -0.1 0.1 0.1 0.1 -0.7 0.2 0.5 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 2.1 1.0 -1.3 0.1 -0.2 -0.2 1.5 0.2 -0.6 0.1 0.6 -0.7 -0.3 0.8 1.2 -0.2
Whole body fat mass 0.3 1.2 5.2 -0.4 1.3 1.6 2.3 0.8 0.2 1.4 -0.1 -0.5 0.7 -0.1 1.7 -0.2 0.8 -1.0
Leg fat mass (right) 0.2 0.7 2.8 -0.5 0.4 1.3 1.7 1.3 -0.3 0.9 0.6 -0.9 0.2 0.3 0.9 -0.7 0.3 -0.8
Arm predicted mass (right) 0.2 0.9 2.3 -0.2 -1.5 0.8 -0.0 1.2 -0.7 -0.5 1.2 -1.4 -0.4 0.9 -1.1 -1.3 -0.1 -1.1
Pulse rate, automated reading 2.0 6.4 16.0 1.9 -1.3 1.0 -0.1 4.0 -2.3 1.2 3.4 -3.5 -3.2 -2.0 -1.4 -3.1 -1.8 -3.9
Alcohol intake frequency. 0.9 2.1 5.2 0.4 0.6 -0.6 -0.3 -2.2 1.6 -1.4 -2.0 2.0 1.5 -0.3 0.5 2.3 1.5 1.8
Comparative height size at age 10 0.2 0.9 2.2 -0.2 1.4 1.1 1.5 0.8 -1.1 0.9 1.1 -0.8 0.4 0.0 1.1 -0.9 -0.9 -0.6
Number of full sisters 0.4 0.5 3.4 -1.7 -0.3 -0.0 0.6 0.2 -0.4 -0.1 0.3 -0.1 0.4 1.8 0.1 -0.6 -0.3 0.7
Suffer from ‘nerves’ 1.5 2.4 9.1 1.2 3.0 0.9 2.3 -0.1 -0.7 1.3 -0.4 0.7 -0.7 -2.4 2.9 0.6 0.2 -1.3
Overall health rating 0.3 0.6 3.5 0.4 -0.0 0.3 0.3 0.8 0.0 0.8 0.9 -1.1 -1.0 -0.3 -0.3 -0.6 0.4 -1.9
Chest pain or discomfort 0.3 0.4 1.5 -1.2 0.5 -0.5 1.0 0.7 -0.6 0.2 0.5 -0.4 -0.5 0.4 0.8 -0.4 0.3 -0.7
Had major operations 1.1 1.3 4.4 -1.8 1.4 0.6 2.1 -0.2 -0.1 0.6 -0.2 0.6 1.3 1.4 2.0 0.1 -0.1 1.2
Age at last live birth 0.5 0.8 2.3 -0.2 1.5 0.6 0.8 -1.5 -0.4 0.5 -0.3 0.7 1.2 0.1 1.1 0.3 -0.8 1.2
Family relationship satisfaction 0.7 0.9 3.2 -1.6 0.0 -1.5 -0.5 -0.3 -1.5 -0.6 -0.4 0.6 0.3 1.0 0.4 -0.7 -1.8 0.3
Leg pain on walking 0.4 0.5 1.8 -1.0 0.7 -0.0 0.8 -1.3 -0.1 0.1 -0.1 0.5 0.3 1.2 0.8 0.2 0.4 0.5
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 1.7 0.1 -0.9 0.3 -0.2 1.3 -0.3 0.6 0.8 -0.9 -1.3 0.1 -0.6 -1.0 -0.3 -0.8
Commuting to job workplace: Car/motor vehicle 0.6 0.7 1.8 -0.8 -0.6 0.4 0.7 1.3 -0.2 0.7 0.7 -1.3 -1.0 0.7 -0.2 -1.0 0.3 -1.3
Illness, injury, bereavement, stress in last 2 years 1.2 1.4 4.5 1.6 0.9 2.1 1.7 0.0 0.1 1.0 0.5 -0.7 -1.6 -1.6 1.1 -0.7 0.5 -1.6
Medication: Aspirin 2.5 3.3 7.4 0.5 0.8 1.6 2.3 2.7 -0.8 2.6 2.2 -2.7 -1.9 -0.7 0.5 -1.9 0.1 -2.4
Supplements: Vitamin C 0.9 1.1 1.8 -1.2 1.1 -1.2 0.3 -1.3 0.7 -0.8 -1.3 1.4 0.5 0.5 1.1 1.2 1.2 1.1
Knee pain experienced in last month 2.0 3.2 8.0 0.3 2.7 1.6 2.7 -1.6 1.9 1.7 -1.3 1.1 0.3 -0.1 2.5 1.9 2.8 0.4
Hypertension (Self-reported) 0.7 2.0 7.4 0.5 0.7 0.8 1.9 2.3 0.1 1.8 1.6 -1.9 -0.8 -0.7 0.6 -1.1 0.7 -2.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.6 0.4 -0.2 -0.3 -0.4 -0.1 -0.1 0.0 -0.2 0.7 -0.2 -0.7 0.2 0.5 -0.3 -0.2
Illnesses of father: Heart disease 1.3 1.8 4.3 -1.3 0.4 0.0 0.8 2.1 -1.4 1.6 2.0 -1.6 -1.2 0.9 -0.1 -1.9 -0.7 -1.7
Illnesses of siblings: Diabetes 0.8 1.0 6.5 -0.3 0.2 0.6 1.0 0.7 -0.8 0.4 0.4 -1.0 -2.6 -0.2 0.4 -1.2 0.4 -1.6
Smoking status: Previous 0.4 0.6 1.8 0.5 1.0 0.7 1.0 -1.2 0.4 0.5 -0.6 0.7 1.0 -0.3 1.3 0.5 0.0 0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.5 2.2 -0.3 -0.4 -1.2 -1.5 -0.8 -0.3 -0.2 -0.4 0.8 0.5 0.5 -0.8 0.3 -0.7 1.0
Whole body fat-free mass 0.1 0.5 1.5 -0.5 -1.1 0.8 0.0 0.6 -0.5 -0.3 0.8 -0.9 -0.1 1.2 -0.8 -0.9 -0.0 -0.6
Leg fat-free mass (right) 0.1 0.6 2.5 -1.2 0.1 0.5 0.8 -0.5 0.6 -0.1 -0.6 0.3 1.0 1.6 0.4 0.4 1.1 0.2
Arm fat percentage (left) 0.4 1.5 5.2 -1.0 1.7 0.7 2.2 0.1 0.6 1.1 -1.0 0.5 1.7 0.2 2.3 0.7 0.8 0.2
Average weekly red wine intake 1.0 1.5 4.0 0.6 1.0 0.5 1.5 1.5 -1.0 0.2 1.3 -1.4 -1.8 -1.4 0.8 -1.2 -0.4 -2.0
Handedness (chirality/laterality): Left-handed 0.9 1.1 3.1 1.8 -0.2 1.8 0.4 0.3 1.3 0.3 -0.0 -0.6 -1.7 -1.2 -0.2 -0.1 1.2 -1.1
Mood swings 0.5 0.8 2.7 0.3 -0.0 1.6 0.8 0.4 0.6 1.7 0.7 -1.0 -1.3 0.5 -0.3 -0.6 1.1 -0.8
Loneliness, isolation 0.8 1.2 2.7 -1.4 -1.1 -1.6 -1.3 -0.3 -1.1 -1.6 0.3 0.1 -0.4 1.6 -1.3 -0.6 -0.9 0.6
Long-standing illness, disability or infirmity 0.9 1.3 6.1 -2.1 -0.6 -0.9 0.5 0.4 -0.3 -0.4 0.1 0.3 1.7 2.5 0.2 0.0 -0.3 2.0
Ever had bowel cancer screening 0.4 0.5 1.9 0.2 -0.6 0.6 -0.0 0.7 0.0 0.1 0.9 -1.4 -0.9 0.5 -1.1 -1.0 0.1 0.0
Diabetes diagnosed by doctor 0.6 1.0 3.9 0.4 -0.0 -0.1 0.1 0.9 -1.2 0.1 1.2 -1.0 -2.0 -0.5 -0.4 -1.4 -1.1 -1.7
Ever had stillbirth, spontaneous miscarriage or termination 3.4 3.6 9.6 2.5 0.5 1.7 0.5 -3.1 2.8 1.5 -1.8 1.7 1.0 -1.5 0.8 2.6 2.6 1.0
Friendships satisfaction 0.3 0.4 1.1 0.7 -0.8 0.8 -0.9 -0.1 0.1 0.4 0.1 -0.6 -1.0 -0.1 -1.0 -0.5 -0.2 -0.4
Qualifications: nursing, teaching 1.9 3.0 7.0 -1.3 -2.0 -0.8 -2.0 0.7 -1.9 -0.2 1.6 -1.8 -1.8 1.9 -2.6 -2.5 -2.0 -1.0
Commuting to job workplace: Walk 0.5 0.5 3.5 -1.0 -0.8 0.4 -0.4 0.3 0.4 -0.3 0.6 -0.3 -0.3 1.9 -1.3 -0.5 0.3 0.2
Eye problems/disorders: Cataract 0.6 0.7 5.0 -1.5 -0.7 -2.2 -0.2 0.2 -1.0 -0.6 -0.0 0.3 0.3 0.6 0.2 -0.4 -1.0 0.2
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 2.1 -0.4 -0.1 0.1 -0.7 -1.4 0.6 -0.3 -0.7 0.5 0.2 1.0 -0.6 0.2 0.2 0.8
Medication for cholesterol 0.2 0.3 2.0 0.5 -0.2 0.1 -0.6 -0.9 0.1 -0.5 -0.2 0.6 0.2 -0.4 -0.0 0.4 -0.8 1.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.2 1.4 5.5 0.6 -1.9 -1.6 -2.4 0.5 -0.4 -1.8 0.2 0.2 -0.3 -0.5 -1.9 -0.1 -0.5 -0.7
Back pain experienced in last month 0.5 0.8 2.3 -0.9 0.1 -0.7 0.2 -1.3 0.1 -1.0 -0.9 1.2 1.5 1.0 0.7 1.0 0.5 0.8
Mineral and other dietary supplements 0.7 0.9 3.7 0.0 -1.3 -1.4 -1.9 -0.8 -0.2 -1.1 -1.1 1.2 0.4 -0.2 -0.8 0.3 -0.5 0.0
Breast cancer (self-reported) 0.5 0.6 2.2 -0.6 1.5 0.6 1.5 -0.1 0.2 0.4 0.0 -0.0 -1.0 0.1 1.2 -0.0 0.8 -0.2
Asthma (self-reported) 0.5 1.0 3.4 0.5 -0.4 -0.2 -0.5 -0.9 1.1 -0.2 -1.5 1.5 0.7 0.0 0.1 1.6 1.2 1.8
Osteoporosis (self-reported) 2.0 2.4 7.2 -1.1 -0.2 -2.1 -1.5 -1.3 -1.2 -2.4 -1.3 2.7 0.8 0.3 0.7 0.9 -2.1 2.1
Osteoarthritis (self-reported) 1.8 2.3 8.9 -1.0 2.5 0.9 3.0 -1.5 0.9 0.6 -0.8 0.8 0.8 0.8 2.6 0.8 1.9 -0.4
Medication: Aspirin 2.8 3.6 8.1 0.6 0.7 1.7 2.1 2.7 -0.9 2.6 2.3 -2.8 -2.4 -0.8 0.3 -2.1 0.2 -2.6
Medication: Gliclazide 1.2 1.4 4.1 -0.7 -2.0 -0.9 -1.6 0.9 -0.8 -1.4 0.7 -0.5 -0.5 1.4 -1.8 -1.2 -1.4 0.0
Illnesses of father: None of the above (group 1) 2.9 3.5 11.2 0.9 0.1 -2.0 -1.8 -3.3 0.5 -2.4 -2.6 2.5 2.0 -1.4 0.3 2.3 0.1 1.9
Smoking status: Current 0.2 0.4 1.5 0.4 -0.1 0.5 0.4 0.4 -0.4 0.5 0.6 -0.7 -1.2 -0.5 0.0 -0.7 -0.2 -1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.5 3.2 11.1 1.0 -2.3 -2.2 -3.3 0.3 -1.6 -1.5 1.5 -0.9 -2.0 -1.0 -2.9 -1.0 -1.2 -1.2
Whole body water mass 0.1 0.4 1.5 -0.6 -0.9 0.8 0.2 0.6 -0.4 -0.3 0.7 -0.8 0.0 1.2 -0.7 -0.8 0.1 -0.6
Leg predicted mass (right) 0.1 0.5 2.5 -1.2 0.0 0.5 0.7 -0.4 0.5 -0.1 -0.5 0.2 0.9 1.6 0.3 0.3 1.0 0.2
Arm fat mass (left) 0.2 1.0 3.4 -0.7 1.3 0.9 1.8 0.1 0.5 0.6 -0.9 0.4 1.4 0.3 1.8 0.6 0.9 -0.2
Number of self-reported non-cancer illnesses 0.4 0.7 3.2 -0.1 0.6 0.5 1.8 1.1 -0.3 1.4 0.5 -0.2 -0.1 -0.3 1.5 -0.2 -0.1 -0.7
Average weekly champagne plus white wine intake 1.3 1.8 6.9 -0.5 -2.6 -1.3 -2.2 0.2 -0.5 -1.9 0.7 -0.5 -0.9 1.4 -2.3 -0.7 -0.4 0.2
Miserableness 0.5 0.9 3.5 0.8 0.6 1.9 0.7 -0.3 1.6 1.4 0.2 -0.3 -0.2 0.3 -0.2 0.6 1.4 0.7
Guilty feelings 0.5 0.7 2.2 -0.8 1.5 0.4 0.9 -1.3 0.6 0.2 -0.7 1.0 0.8 0.7 1.1 1.0 0.3 0.4
Wears glasses or contact lenses 0.2 0.2 1.5 0.4 1.2 0.4 0.8 -0.2 0.0 -0.3 0.0 0.2 -0.3 -0.5 0.7 0.3 0.3 0.2
Ever taken oral contraceptive pill 0.7 0.7 3.9 0.8 0.8 1.3 1.5 0.0 0.4 2.0 0.3 -0.3 -0.2 -0.5 1.0 -0.2 0.3 -0.0
Hearing aid user 0.8 0.9 3.1 1.0 0.3 -0.2 0.6 1.5 -1.3 1.2 0.7 -0.3 -0.4 -1.8 0.9 -0.3 -1.2 -0.5
Mother’s age at death 0.4 0.5 1.0 0.9 -0.8 0.6 -0.5 0.3 0.0 -0.5 0.8 -1.0 -0.8 -0.4 -1.0 -0.7 0.1 -0.9
Financial situation satisfaction 1.6 1.9 6.0 2.4 -0.7 1.1 -1.2 0.6 0.2 0.8 0.8 -1.5 -2.2 -1.7 -1.6 -0.8 0.3 -2.2
Tinnitus: Yes, now most or all of the time 0.6 0.7 2.5 -1.4 0.2 -0.8 0.6 0.1 -1.2 0.6 0.1 -0.2 -1.6 0.8 0.6 -1.0 -0.6 0.3
Commuting to job workplace: Public transport 1.6 2.0 5.2 -0.3 2.1 0.7 1.1 -2.0 -0.1 0.7 -1.1 2.3 1.6 -0.1 2.1 1.3 -0.5 1.9
Eye problems/disorders: Glaucoma 0.8 0.9 3.2 0.6 1.8 1.2 1.3 -1.1 -0.0 0.3 -0.2 0.7 0.2 -1.1 1.7 0.4 0.3 -0.8
Medication: Blood pressure 0.5 0.9 5.1 0.0 1.1 0.5 1.4 -0.2 1.1 0.8 -0.3 -0.2 -0.2 -0.0 0.7 0.6 2.3 -1.6
Pain type(s) experienced in last month: Hip pain 1.1 1.4 7.0 -2.6 -0.1 -1.7 0.0 -1.2 -0.6 -0.7 -0.1 0.8 1.0 2.6 0.2 0.2 0.0 0.8
Supplements: Fish oil (including cod liver oil) 1.3 1.7 7.2 -0.3 1.3 2.1 2.7 1.0 1.1 1.9 0.7 -1.1 0.4 0.6 1.3 -0.0 1.4 0.3
High cholesterol (Self-reported) 1.7 3.1 15.6 -1.0 -1.1 -0.5 0.3 4.0 -2.4 -0.4 1.8 -1.9 -1.5 0.2 -0.3 -2.5 -1.8 -1.9
Medication: Bendroflumethiazide 1.3 1.9 6.9 0.5 -0.1 1.1 0.9 2.6 -0.8 1.4 2.2 -1.9 -0.7 -0.5 -0.3 -1.4 -0.5 -2.2
Medication: Paracetamol 1.8 2.7 9.7 -0.7 1.4 1.5 2.2 0.3 2.9 1.2 -1.6 0.7 1.4 1.1 1.5 1.6 3.1 1.1
Medication: Lisinopril 1.1 1.4 4.4 2.1 -1.3 -0.6 -1.2 0.6 1.5 -0.7 -1.1 0.4 0.5 -1.9 -0.6 1.3 1.3 -0.3
Medication: Atorvastatin 3.7 4.6 11.9 0.8 -1.7 0.2 -0.6 3.4 -2.4 0.3 2.8 -2.5 -3.5 -1.0 -1.4 -2.9 -1.9 -2.7
Illnesses of father: High blood pressure 0.5 0.6 2.3 0.2 0.0 0.7 0.7 1.3 0.8 0.7 1.2 -1.5 -0.6 0.1 -0.6 -0.6 0.4 -0.5
Alcohol drinker status: Never 0.5 0.5 1.9 0.2 -0.1 -0.7 -1.1 -1.4 0.4 -1.2 -0.4 0.7 0.5 -0.2 -0.6 1.0 0.5 0.3
Ever smoked 0.2 0.4 1.4 0.2 -0.4 0.4 0.3 0.6 -0.8 0.2 0.6 -0.6 -0.4 -0.4 0.2 -1.0 -1.2 -0.7
Basal metabolic rate 0.1 0.4 1.4 -0.7 -0.7 0.9 0.4 0.6 -0.3 -0.1 0.6 -0.8 0.1 1.2 -0.5 -0.7 0.3 -0.6
Leg fat percentage (left) 0.3 1.1 4.2 0.1 1.0 1.3 2.0 1.4 -0.5 1.3 0.6 -0.9 -0.0 -0.7 1.5 -0.7 -0.0 -1.1
Arm fat-free mass (left) 0.2 0.8 1.6 -0.6 -1.3 0.5 -0.0 1.1 -0.9 -0.7 1.1 -1.1 -0.4 1.1 -0.9 -1.2 -0.3 -1.0
Number of operations (self-reported) 0.6 1.0 3.6 -0.1 1.0 1.1 1.9 0.0 1.0 0.9 -0.7 0.8 0.9 -0.2 1.8 0.8 0.7 0.6
Average weekly beer plus cider intake 1.0 1.4 5.2 -1.0 1.2 1.8 1.6 0.4 1.3 2.3 0.4 -0.8 0.5 1.2 0.7 0.0 1.6 0.1
Irritability 0.7 1.2 4.4 2.1 -0.2 2.0 0.7 0.4 1.5 1.3 -0.1 -0.4 -1.0 -1.2 0.1 0.5 1.3 -0.6
Risk taking 3.3 4.9 17.3 -1.0 0.8 -1.5 -0.7 -4.2 1.6 -1.4 -3.2 3.2 2.6 0.9 0.9 3.1 1.8 2.3
Ever had prostate specific antigen (PSA) test 0.3 0.4 2.9 -0.4 -0.3 -0.5 -0.7 -0.2 0.0 -1.7 -0.4 0.6 -0.2 0.7 -0.5 0.3 0.1 0.3
Fractured/broken bones in last 5 years 1.1 1.4 5.7 -1.1 -1.3 -1.5 -1.6 -0.2 -1.1 -2.4 -0.3 0.9 0.5 0.8 -0.8 -0.1 -1.5 1.2
Age started oral contraceptive pill 0.4 0.4 2.5 -0.6 1.6 -0.7 0.8 -0.7 -0.5 -0.6 -0.3 0.0 0.5 -0.3 1.0 0.0 -0.2 0.0
Diastolic blood pressure, automated reading 0.4 1.3 7.3 -0.1 -1.5 -1.2 0.2 2.7 -0.4 0.1 1.4 -1.7 -0.4 -0.2 -0.8 -1.1 -0.3 -1.4
Ever depressed for a whole week 0.3 0.4 1.2 -0.6 0.1 0.9 0.7 0.3 0.8 0.5 0.5 -0.4 0.4 1.1 -0.1 0.1 0.9 0.4
Unable to work because of sickness or disability 0.6 0.7 2.8 0.0 0.4 1.1 0.9 0.8 0.5 1.7 0.3 -1.0 -1.4 0.0 0.1 -0.7 0.8 -1.0
Commuting to job workplace: Cycle 0.9 1.1 3.8 -0.4 -0.9 -1.0 -1.2 -0.4 0.5 -1.8 -0.3 0.9 1.4 1.0 -1.0 0.9 -0.2 1.9
Myopia 0.5 0.7 3.3 1.3 -0.0 -0.3 -0.4 -0.1 -1.3 -0.4 0.5 0.3 -0.7 -1.6 0.2 -0.6 -1.8 0.6
Vascular/heart problems diagnosed by doctor 0.8 2.3 7.4 -0.1 -1.0 -0.5 -2.1 -2.4 0.6 -1.9 -1.8 1.9 1.1 0.6 -0.8 1.4 -0.3 2.7
Cholesterol lowering medication 0.6 0.9 4.8 0.7 0.2 -0.0 0.4 0.8 -1.3 0.5 0.9 -0.8 -1.4 -0.9 0.1 -1.0 -0.4 -2.2
Medication: Omeprazole (e.g. Zanprol) 0.8 0.9 3.6 0.4 0.6 0.9 0.7 1.5 0.4 1.1 0.9 -1.5 -0.8 -0.4 -0.3 -0.9 0.2 -1.9
Pain experienced in last month 0.2 0.4 1.0 -0.5 -0.5 -1.0 -0.7 0.5 -1.0 -0.9 -0.1 0.2 -0.1 -0.3 -0.2 -0.5 -0.9 0.4
Supplements: Calcium 2.1 2.4 7.8 1.5 2.6 0.9 1.6 -1.5 0.1 0.7 -1.4 1.5 0.5 -2.4 2.8 1.3 -0.1 0.5
Basal cell carcinoma (self-reported) 1.0 1.2 4.3 1.0 -0.0 1.2 -0.2 0.1 -1.4 1.0 0.9 -1.0 -2.1 -0.7 -0.3 -1.1 -0.7 -1.9
Heart attack/myocardial infarction (self-reported) 1.9 2.4 5.2 0.8 1.7 1.6 2.0 0.8 -1.5 2.0 1.5 -1.1 -1.4 -1.9 1.8 -1.1 -0.6 -2.3
Deep venous thrombosis (DVT) (self-reported) 0.1 0.2 0.6 -0.7 0.0 0.1 0.4 0.2 -0.2 -0.4 -0.4 0.3 -0.2 0.0 0.8 0.1 0.6 -0.4
Heart disease (siblings) 0.2 0.3 1.6 0.2 0.2 0.6 0.5 0.4 0.4 0.8 -0.0 0.4 1.2 -0.1 0.7 0.3 0.1 0.5
Alcohol drinker status: Previous 0.3 0.4 2.5 1.6 -0.6 0.3 -0.3 0.2 1.0 -0.1 -0.4 0.2 -0.3 -0.8 -0.3 0.4 0.5 0.3
Pack years of smoking 1.6 2.3 10.3 2.1 1.1 3.2 2.0 -0.0 1.4 2.6 0.3 -0.2 0.7 -1.4 1.2 0.9 1.3 -0.2
Impedance of whole body 0.2 1.0 3.5 0.8 1.9 0.4 0.6 0.6 -0.3 1.6 0.7 -1.0 -0.9 -1.6 0.5 -0.5 -0.4 -1.3
Leg fat mass (left) 0.2 0.8 3.7 -0.6 0.7 1.3 1.9 1.1 -0.3 0.9 0.4 -0.7 0.3 0.3 1.2 -0.6 0.3 -0.8
Arm predicted mass (left) 0.1 0.6 1.3 -0.4 -1.0 0.9 0.3 1.0 -0.7 -0.3 1.0 -1.1 -0.4 0.9 -0.6 -1.1 -0.1 -1.1